KEGG T01001: 10018

Homo sapiens (human): 10018

Entry

10018 CDS T01001

Gene name

BCL2L11, BAM, BIM, BOD

Definition

(RefSeq) BCL2 like 11

K16341

Bcl-2-like protein 11

Organism

hsa Homo sapiens (human)

Pathway

hsa01521

EGFR tyrosine kinase inhibitor resistance

hsa04068

FoxO signaling pathway

hsa04151

PI3K-Akt signaling pathway

hsa04210

Apoptosis

hsa04215

Apoptosis - multiple species

hsa04932

Non-alcoholic fatty liver disease (NAFLD)

hsa05169

Epstein-Barr virus infection

hsa05200

Pathways in cancer

hsa05206

MicroRNAs in cancer

hsa05210

Colorectal cancer

Network

nt06131  Apoptosis (viruses and bacteria)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06165  Epstein-Barr virus (EBV)
nt06166  Human papillomavirus (HPV)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06170  Influenza A virus (IAV)
nt06231  Apoptosis
nt06260  Colorectal cancer
nt06267  Small cell lung cancer
nt06414  Apoptosis
nt06463  Parkinson disease

Element

N00098

Intrinsic apoptotic pathway

N00262

EBV EBNA3C to intrinsic apoptotic pathway

N00474

EBV BHRF1 to intrinsic apoptotic pathway

N00585

HSV US3 to intrinsic apoptotic pathway

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    10018 (BCL2L11)
   04151 PI3K-Akt signaling pathway
    10018 (BCL2L11)
09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    10018 (BCL2L11)
   04215 Apoptosis - multiple species
    10018 (BCL2L11)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    10018 (BCL2L11)
   05206 MicroRNAs in cancer
    10018 (BCL2L11)
  09162 Cancer: specific types
   05210 Colorectal cancer
    10018 (BCL2L11)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease (NAFLD)
    10018 (BCL2L11)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    10018 (BCL2L11)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    10018 (BCL2L11)

SSDB

Motif

Pfam:

Bim_N Bclx_interact

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

O43521(Tbio)

UniProt:

O43521

LinkDB

Structure

PDB:

2WH6 4QVF 2NL9 5VWZ 3KJ0 4ZIE 4B4S 3KJ1 4D2M 2VM6 3IO8 3KJ2 6QFI 4ZIF 3IO9 5WOS 4ZIH 4UF3 2V6Q

Position

2q13

AA seq 198 aa
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSP
QGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPP
CQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPR
MVILRLLRYIVRLVWRMH

NT seq 597 nt +upstreamnt +downstreamnt
atggcaaagcaaccttctgatgtaagttctgagtgtgaccgagaaggtagacaattgcag
cctgcggagaggcctccccagctcagacctggggcccctacctccctacagacagagcca
caaggtaatcctgaaggcaatcacggaggtgaaggggacagctgcccccacggcagccct
cagggcccgctggccccacctgccagccctggcccttttgctaccagatccccgcttttc
atctttatgagaagatcctccctgctgtctcgatcctccagtgggtatttctcttttgac
acagacaggagcccagcacccatgagttgtgacaaatcaacacaaaccccaagtcctcct
tgccaggccttcaaccactatctcagtgcaatggcttccatgaggcaggctgaacctgca
gatatgcgcccagagatatggatcgcccaagagttgcggcgtattggagacgagtttaac
gcttactatgcaaggagggtatttttgaataattaccaagcagccgaagaccacccacga
atggttatcttacgactgttacgttacattgtccgcctggtgtggagaatgcattga

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