KEGG   Homo sapiens (human): 10092
Entry
10092             CDS       T01001                                 

Gene name
ARPC5, ARC16, dJ127C7.3, p16-Arc
Definition
(RefSeq) actin related protein 2/3 complex subunit 5
  KO
K05754  actin related protein 2/3 complex, subunit 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10092 (ARPC5)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10092 (ARPC5)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    10092 (ARPC5)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    10092 (ARPC5)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10092 (ARPC5)
   05132 Salmonella infection
    10092 (ARPC5)
   05131 Shigellosis
    10092 (ARPC5)
   05135 Yersinia infection
    10092 (ARPC5)
   05100 Bacterial invasion of epithelial cells
    10092 (ARPC5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10092 (ARPC5)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10092 (ARPC5)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    10092 (ARPC5)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     10092 (ARPC5)
SSDB
Motif
Pfam: P16-Arc UTP15_C Utp12
Other DBs
NCBI-GeneID: 10092
NCBI-ProteinID: NP_005708
OMIM: 604227
HGNC: 708
Ensembl: ENSG00000162704
Vega: OTTHUMG00000035326
Pharos: O15511(Tbio)
UniProt: O15511
LinkDB
Position
1q25.3
AA seq 151 aa
MSKNTVSSARFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALK
NPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDN
SSAMLLQWHEKALAAGGVGSIVRVLTARKTV
NT seq 456 nt   +upstreamnt  +downstreamnt
atgtcgaagaacacagtgtcgtcggcccgcttccggaaggtggacgtggatgaatatgac
gagaacaagttcgtggacgaagaagatgggggcgacggccaggccgggcccgacgagggc
gaggtggactcctgcctgcggcaaggaaacatgacagctgccctacaggcagctctgaag
aacccccctatcaacaccaagagtcaggcagtgaaggaccgggcaggcagcattgtcttg
aaggtgctcatctcttttaaagctaatgatatagaaaaggcagttcaatctctggacaag
aatggtgtggatctcctaatgaagtatatttataaaggatttgagagcccgtctgacaat
agcagtgctatgttactgcaatggcatgaaaaggcacttgctgctggaggagtagggtcc
attgttcgtgtcttgactgcaagaaaaactgtgtag

KEGG   Homo sapiens (human): 10093
Entry
10093             CDS       T01001                                 

Gene name
ARPC4, ARC20, P20-ARC
Definition
(RefSeq) actin related protein 2/3 complex subunit 4
  KO
K05755  actin related protein 2/3 complex, subunit 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10093 (ARPC4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10093 (ARPC4)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    10093 (ARPC4)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    10093 (ARPC4)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10093 (ARPC4)
   05132 Salmonella infection
    10093 (ARPC4)
   05131 Shigellosis
    10093 (ARPC4)
   05135 Yersinia infection
    10093 (ARPC4)
   05100 Bacterial invasion of epithelial cells
    10093 (ARPC4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10093 (ARPC4)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10093 (ARPC4)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    10093 (ARPC4)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     10093 (ARPC4)
SSDB
Motif
Pfam: ARPC4 Sm_like DUF5747
Other DBs
NCBI-GeneID: 10093
NCBI-ProteinID: NP_005709
OMIM: 604226
HGNC: 707
Ensembl: ENSG00000241553
Vega: OTTHUMG00000133768
Pharos: P59998(Tbio)
UniProt: P59998
LinkDB
Position
3p25.3
AA seq 168 aa
MTATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEK
VLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITN
FHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF
NT seq 507 nt   +upstreamnt  +downstreamnt
atgactgccactctccgcccctacctgagtgccgtgcgggccacattgcaggctgccctc
tgcctggagaacttctcctcccaggttgtggaacgacacaacaagccggaagtggaagtc
aggagtagcaaagagctcctgttacaacctgtgaccatcagcaggaatgagaaggaaaag
gttctgattgagggctccatcaactctgtccgggtcagcattgctgtgaaacaggctgat
gagatcgagaagattttgtgccacaagttcatgcgcttcatgatgatgcgagcagagaac
ttctttatccttcgaaggaagcctgtggaggggtatgatatcagctttctgatcaccaac
ttccacacagagcagatgtacaaacacaagttggtggactttgtgatccacttcatggag
gagattgacaaggagatcagtgagatgaagctgtcagtcaatgcccgtgcccgcattgtg
gctgaagagttccttaagaatttttaa

KEGG   Homo sapiens (human): 10094
Entry
10094             CDS       T01001                                 

Gene name
ARPC3, ARC21, p21-Arc
Definition
(RefSeq) actin related protein 2/3 complex subunit 3
  KO
K05756  actin related protein 2/3 complex, subunit 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10094 (ARPC3)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10094 (ARPC3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    10094 (ARPC3)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    10094 (ARPC3)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10094 (ARPC3)
   05132 Salmonella infection
    10094 (ARPC3)
   05131 Shigellosis
    10094 (ARPC3)
   05135 Yersinia infection
    10094 (ARPC3)
   05100 Bacterial invasion of epithelial cells
    10094 (ARPC3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10094 (ARPC3)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10094 (ARPC3)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    10094 (ARPC3)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     10094 (ARPC3)
SSDB
Motif
Pfam: P21-Arc
Other DBs
NCBI-GeneID: 10094
NCBI-ProteinID: NP_001265485
OMIM: 604225
HGNC: 706
Ensembl: ENSG00000111229
Vega: OTTHUMG00000134333
Pharos: O15145(Tbio)
UniProt: O15145
LinkDB
Position
12q24.11
AA seq 178 aa
MPAYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDTDIVDEAIYYFKANVFFKNYEI
KNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFPLNAIYAKP
ANKQEDEVMRAYLQQLRQETGLRLCEKVFDPQNDKPSKWWTCFVKRQFMNKSLSGPGQ
NT seq 537 nt   +upstreamnt  +downstreamnt
atgccggcttaccactcttctctcatggatcctgataccaaactcatcggaaacatggca
ctgttgcctatcagaagtcaattcaaaggacctgcccccagagagacaaaagatacagat
attgtggatgaagccatctattacttcaaggccaatgtcttcttcaaaaactatgaaatt
aagaatgaagctgataggaccttgatatatataactctctacatttctgaatgtctgaag
aaactgcaaaagtgcaattccaaaagccaaggtgagaaagaaatgtatacgctgggaatc
actaattttcccattcctggagagcctggttttccacttaacgcaatttatgccaaacct
gcaaacaaacaggaagatgaagtgatgagagcctatttacaacagctaaggcaagagact
ggactgagactttgtgagaaagttttcgaccctcagaatgataaacccagcaagtggtgg
acttgctttgtgaagagacagttcatgaacaagagtctttcaggacctggacagtga

KEGG   Homo sapiens (human): 10095
Entry
10095             CDS       T01001                                 

Gene name
ARPC1B, ARC41, IMD71, PLTEID, p40-ARC, p41-ARC
Definition
(RefSeq) actin related protein 2/3 complex subunit 1B
  KO
K05757  actin related protein 2/3 complex, subunit 1A/1B
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10095 (ARPC1B)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10095 (ARPC1B)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    10095 (ARPC1B)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    10095 (ARPC1B)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10095 (ARPC1B)
   05132 Salmonella infection
    10095 (ARPC1B)
   05131 Shigellosis
    10095 (ARPC1B)
   05135 Yersinia infection
    10095 (ARPC1B)
   05100 Bacterial invasion of epithelial cells
    10095 (ARPC1B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10095 (ARPC1B)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10095 (ARPC1B)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    10095 (ARPC1B)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     10095 (ARPC1B)
SSDB
Motif
Pfam: WD40 ANAPC4_WD40 eIF2A
Other DBs
NCBI-GeneID: 10095
NCBI-ProteinID: NP_005711
OMIM: 604223
HGNC: 704
Ensembl: ENSG00000130429
Vega: OTTHUMG00000154552
Pharos: O15143(Tbio)
UniProt: O15143 A4D275
LinkDB
Position
7q22.1
AA seq 372 aa
MAYHSFLVEPISCHAWNKDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDW
APESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVI
SICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERP
APTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATL
ASETLPLLALTFITDNSLVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQSSQRGLTARE
RFQNLDKKASSEGGTAAGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVK
SLESALKDLKIK
NT seq 1119 nt   +upstreamnt  +downstreamnt
atggcctaccacagcttcctggtggagcccatcagctgccacgcctggaacaaggaccgc
acccagattgccatctgccccaacaaccatgaggtgcatatctatgaaaagagcggtgcc
aaatggaccaaggtgcacgagctcaaggagcacaacgggcaggtgacaggcatcgactgg
gcccccgagagtaaccgtattgtgacctgcggcacagaccgcaacgcctacgtgtggacg
ctgaagggccgcacatggaagcccacgctggtcatcctgcggatcaaccgggctgcccgc
tgcgtgcgctgggcccccaacgagaacaagtttgctgtgggcagcggctctcgtgtgatc
tccatctgttatttcgagcaggagaatgactggtgggtttgcaagcacatcaagaagccc
atccgctccaccgtcctcagcctggactggcaccccaacaatgtgctgctggctgccggc
tcctgtgacttcaagtgtcggatcttttcagcctacatcaaggaggtggaggaacggccg
gcacccaccccgtggggctccaagatgccctttggggaactgatgttcgaatccagcagt
agctgcggctgggtacatggcgtctgtttctcagccagcgggagccgcgtggcctgggta
agccacgacagcaccgtctgcctggctgatgccgacaagaagatggccgtcgcgactctg
gcctctgaaacactaccactgctggcgctgaccttcatcacagacaacagcctggtggca
gcgggccacgactgcttcccggtgctgttcacctatgacgccgccgcggggatgctgagc
ttcggcgggcggctggacgttcctaagcagagctcgcagcgtggcttgacggcccgcgag
cgcttccagaacctggacaagaaggcgagctccgagggtggcacggctgcgggcgcgggc
ctagactcgctgcacaagaacagcgtcagccagatctcggtgctcagcggcggcaaggcc
aagtgctcgcagttctgcaccactggcatggatggcggcatgagtatctgggatgtgaag
agcttggagtcagccttgaaggacctcaagatcaaatga

KEGG   Homo sapiens (human): 10096
Entry
10096             CDS       T01001                                 

Gene name
ACTR3, ARP3
Definition
(RefSeq) actin related protein 3
  KO
K18584  actin-related protein 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10096 (ACTR3)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10096 (ACTR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    10096 (ACTR3)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    10096 (ACTR3)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10096 (ACTR3)
   05132 Salmonella infection
    10096 (ACTR3)
   05131 Shigellosis
    10096 (ACTR3)
   05135 Yersinia infection
    10096 (ACTR3)
   05100 Bacterial invasion of epithelial cells
    10096 (ACTR3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10096 (ACTR3)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10096 (ACTR3)
   04147 Exosome [BR:hsa04147]
    10096 (ACTR3)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    10096 (ACTR3)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     10096 (ACTR3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   10096 (ACTR3)
  Exosomal proteins of other body fluids (saliva and urine)
   10096 (ACTR3)
  Exosomal proteins of bladder cancer cells
   10096 (ACTR3)
SSDB
Motif
Pfam: Actin MreB_Mbl ALP_N FtsA Robl_LC7
Other DBs
NCBI-GeneID: 10096
NCBI-ProteinID: NP_005712
OMIM: 604222
HGNC: 170
Ensembl: ENSG00000115091
Vega: OTTHUMG00000153497
Pharos: P61158(Tbio)
UniProt: P61158 A0A024RAI1
LinkDB
Position
2q14.1
AA seq 418 aa
MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDF
FIGDEAIEKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTP
ENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPV
AEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVK
EFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVV
DEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKP
KPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS
NT seq 1257 nt   +upstreamnt  +downstreamnt
atggcgggacggctgccggcctgtgtggtggactgtggcacggggtatacaaaactagga
tatgctggaaatacagaaccacagtttatcatcccttcctgtattgctattaaggagtca
gcaaaagtgggtgatcaagctcaaaggagggtgatgaaaggtgttgatgacctagacttc
ttcattggtgatgaagcaatagaaaaacctacatatgcaacaaagtggccaatccgccat
ggtatagttgaagattgggacttaatggaaaggtttatggagcaagtgatctttaaatat
ttaagggcagaacctgaagaccattattttcttttgactgaacctccattgaatactcca
gaaaacagggaatatactgctgaaataatgtttgagtccttcaatgttccaggcttgtac
attgctgtgcaggctgttcttgccttagctgcatcttggacctcaagacaagtaggagaa
cggacgttgaccggtacggtaatagacagtggagatggtgtcactcatgtcattcctgtg
gctgaagggtatgtgattggcagctgtattaaacacattccaatcgcaggacgagatata
acatattttattcagcaactgctgagagaccgagaagtaggaatccctccagaacaatcc
ttggaaactgctaaggcagtaaaggagcgctatagttatgtctgcccagatttagtaaaa
gaatttaacaagtatgatacagatgggtcaaaatggattaaacagtatactggaatcaat
gctatctcaaagaaagagttttctatcgatgttggttatgagagatttttgggacctgaa
atcttttttcatccagagtttgctaatccagactttacacaacctatctcagaagttgta
gatgaagtaattcagaattgtcctattgatgtcagacgtcctctctacaagaatattgtc
ctctctggaggttcaaccatgttcagggactttggacgtcgcttgcaaagagatttgaaa
agaactgtagatgcccggctgaaattaagtgaggaattgagtggtggtagattgaagcca
aaacctattgatgtacaagtcattacacaccacatgcagcgatatgcagtttggtttgga
ggatcaatgctggcttccacgcctgagttctaccaagtatgccacaccaaaaaggattat
gaagaaattggacctagcatttgtcgtcacaatccagtgtttggagtcatgtcgtaa

KEGG   Homo sapiens (human): 10097
Entry
10097             CDS       T01001                                 

Gene name
ACTR2, ARP2
Definition
(RefSeq) actin related protein 2
  KO
K17260  actin-related protein 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10097 (ACTR2)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10097 (ACTR2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    10097 (ACTR2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    10097 (ACTR2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10097 (ACTR2)
   05132 Salmonella infection
    10097 (ACTR2)
   05131 Shigellosis
    10097 (ACTR2)
   05135 Yersinia infection
    10097 (ACTR2)
   05100 Bacterial invasion of epithelial cells
    10097 (ACTR2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10097 (ACTR2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10097 (ACTR2)
   04147 Exosome [BR:hsa04147]
    10097 (ACTR2)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    10097 (ACTR2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     10097 (ACTR2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   10097 (ACTR2)
  Exosomal proteins of other body fluids (saliva and urine)
   10097 (ACTR2)
  Exosomal proteins of bladder cancer cells
   10097 (ACTR2)
SSDB
Motif
Pfam: Actin
Other DBs
NCBI-GeneID: 10097
NCBI-ProteinID: NP_005713
OMIM: 604221
HGNC: 169
Ensembl: ENSG00000138071
Vega: OTTHUMG00000129540
Pharos: P61160(Tbio)
UniProt: P61160
LinkDB
Position
2p14
AA seq 394 aa
MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDE
ASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNR
EKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTR
RLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVL
VESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKH
IVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAV
LADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR
NT seq 1185 nt   +upstreamnt  +downstreamnt
atggacagccagggcaggaaggtggtggtgtgcgacaacggcaccgggtttgtgaagtgt
ggatatgcaggctctaactttccagaacacatcttcccagctttggttggaagacctatt
atcagatcaaccaccaaagtgggaaacattgaaatcaaggatcttatggttggtgatgag
gcaagtgaattacgatcaatgttagaagttaactaccctatggaaaatggcatagtacga
aattgggatgacatgaaacacctgtgggactacacatttggaccagagaaacttaatata
gataccagaaattgtaaaatcttactcacagaacctcctatgaacccaaccaaaaacaga
gagaagattgtagaggtaatgtttgaaacttaccagttttccggtgtatatgtagccatc
caggcagttctgactttgtacgctcaaggtttattgactggtgtagtggtagactctgga
gatggtgtgactcacatttgcccagtatatgaaggcttttctctccctcatcttaccagg
agactggatattgctgggagggatataactagatatcttatcaagctacttctgttgcga
ggatacgccttcaaccactctgctgattttgaaacggttcgcatgattaaagaaaaactg
tgttacgtgggatataatattgagcaagagcagaaactggccttagaaaccacagtatta
gttgaatcttatacactcccagatggacgtatcatcaaagttgggggagagagatttgaa
gcaccagaagctttatttcagcctcacttgatcaatgttgaaggagttggtgttgctgaa
ttgctttttaacacaattcaggcagctgacattgataccagatctgaattctacaaacac
attgtgctttctggagggtctactatgtatcctggcctgccatcacggttggaacgagaa
cttaaacagctttacttagaacgagttttgaagggtgatgtggaaaaactttctaaattt
aagatccgcattgaagacccaccccgcagaaagcacatggtattcctgggtggtgcagtt
ctagcggatatcatgaaagacaaagacaacttttggatgacccgacaagagtaccaagaa
aagggtgtccgtgtgctagagaaacttggtgtgactgttcgataa

KEGG   Homo sapiens (human): 10109
Entry
10109             CDS       T01001                                 

Gene name
ARPC2, ARC34, PNAS-139, PRO2446, p34-Arc
Definition
(RefSeq) actin related protein 2/3 complex subunit 2
  KO
K05758  actin related protein 2/3 complex, subunit 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10109 (ARPC2)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10109 (ARPC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    10109 (ARPC2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    10109 (ARPC2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10109 (ARPC2)
   05132 Salmonella infection
    10109 (ARPC2)
   05131 Shigellosis
    10109 (ARPC2)
   05135 Yersinia infection
    10109 (ARPC2)
   05100 Bacterial invasion of epithelial cells
    10109 (ARPC2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10109 (ARPC2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10109 (ARPC2)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    10109 (ARPC2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     10109 (ARPC2)
SSDB
Motif
Pfam: P34-Arc ARPC4
Other DBs
NCBI-GeneID: 10109
NCBI-ProteinID: NP_005722
OMIM: 604224
HGNC: 705
Ensembl: ENSG00000163466
Vega: OTTHUMG00000133618
Pharos: O15144(Tbio)
UniProt: O15144 Q53R19
LinkDB
Position
2q35
AA seq 300 aa
MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSIS
LKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNC
FASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKV
FMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNT
INLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR
NT seq 903 nt   +upstreamnt  +downstreamnt
atgatcctgctggaggtgaacaaccgcatcatcgaggagacgctcgcgctcaagttcgag
aacgcggccgccggaaacaaaccggaagcagtagaagtaacatttgcagatttcgatggg
gtcctctatcatatttcaaatcctaatggagacaaaacaaaagtgatggtcagtatttct
ttgaaattctacaaggaacttcaggcacatggtgctgatgagttattaaagagggtgtac
gggagtttcttggtaaatccagaatcaggatacaatgtctctttgctatatgaccttgaa
aatcttccggcatccaaggattccattgtgcatcaagctggcatgttgaagcgaaattgt
tttgcctctgtctttgaaaaatacttccaattccaagaagagggcaaggaaggagagaac
agggcagttatccattatagggatgatgagaccatgtatgttgagtctaaaaaggacaga
gtcacagtagtcttcagcacagtgtttaaggatgacgacgatgtggtcattggaaaggtg
ttcatgcaggagttcaaagaaggacgcagagccagccacacagccccacaggtcctcttt
agccacagggaacctcctctggagctgaaagacacagacgccgctgtgggtgacaacatt
ggctacattacctttgtgctgttccctcgtcacaccaatgccagtgctcgagacaacacc
atcaacctgatccacacgttccgggactacctgcactaccacatcaagtgctctaaggcc
tatattcacacacgtatgcgggcgaaaacgtctgacttcctcaaggtgctgaaccgcgca
cgcccagatgccgagaaaaaagaaatgaaaacaatcacggggaagacgttttcatcccgc
taa

KEGG   Homo sapiens (human): 10552
Entry
10552             CDS       T01001                                 

Gene name
ARPC1A, Arc40, HEL-68, HEL-S-307, SOP2Hs, SOP2L
Definition
(RefSeq) actin related protein 2/3 complex subunit 1A
  KO
K05757  actin related protein 2/3 complex, subunit 1A/1B
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10552 (ARPC1A)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10552 (ARPC1A)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    10552 (ARPC1A)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    10552 (ARPC1A)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10552 (ARPC1A)
   05132 Salmonella infection
    10552 (ARPC1A)
   05131 Shigellosis
    10552 (ARPC1A)
   05135 Yersinia infection
    10552 (ARPC1A)
   05100 Bacterial invasion of epithelial cells
    10552 (ARPC1A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10552 (ARPC1A)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10552 (ARPC1A)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    10552 (ARPC1A)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     10552 (ARPC1A)
SSDB
Motif
Pfam: WD40 ANAPC4_WD40 LytB_WW
Other DBs
NCBI-GeneID: 10552
NCBI-ProteinID: NP_006400
OMIM: 604220
HGNC: 703
Ensembl: ENSG00000241685
Vega: OTTHUMG00000154553
Pharos: Q92747(Tbio)
UniProt: Q92747 V9HVZ6
LinkDB
Position
7q22.1
AA seq 370 aa
MSLHQFLLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWVKAHELKEHNGHITGIDW
APKSDRIVTCGADRNAYVWSQKDGVWKPTLVILRINRAATFVKWSPLENKFAVGSGARLI
SVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVDEKP
ASTPWGSKMPFGQLMSEFGGSGTGGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVS
TLKTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDIPKQSIQRNMSAM
ERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKTL
ESSIQGLRIM
NT seq 1113 nt   +upstreamnt  +downstreamnt
atgtcactgcatcagtttttactagagccaatcacctgtcatgcctggaacagggatcgt
actcagattgccctcagtcccaataatcacgaagtgcacatctataagaagaacgggagc
cagtgggtgaaagctcatgaactcaaggagcacaacggacacatcacaggtattgactgg
gctcccaagagcgaccgcattgtcacttgtggggcagaccgcaatgcctatgtctggagt
cagaaagatggtgtttggaagccaaccctggtgatcctgagaattaatcgcgcagctact
tttgtgaagtggtcccccctagagaacaaatttgctgtgggaagtggagcacgactcatt
tctgtttgttactttgagtctgaaaatgactggtgggtgagcaagcacattaaaaagccg
attcgctccacagtcctcagcttggattggcatcccaacaacgttttgctggcagcagga
tcatgtgacttcaaatgcagagtgttttctgcctacattaaagaagtggatgaaaagcca
gccagcacgccctggggcagcaagatgccttttgggcagctgatgtcagagtttggtggc
agtggcactggtggctgggtccacggggtaagcttctctgccagtgggagccgcctggcc
tgggtcagccacgacagcaccgtgtctgttgctgatgcctcaaaaagtgtgcaggtctcg
actctgaagacagagttcctgccgctcctaagtgtgtcatttgtctcagagaacagcgtc
gtggctgctggccatgactgctgcccaatgctctttaactacgatgaccgcggctgcctg
accttcgtctccaagttagatattccaaaacagagcatccaacgcaacatgtctgccatg
gaacgcttccgcaacatggacaagagagccacaactgaggaccgcaacacggccttggag
acgctgcaccagaatagcatcactcaagtctctatttatgaggtggacaagcaagattgt
cgcaaattttgcactactggcatcgatggagccatgacaatttgggatttcaagaccctc
gagtcttccatccagggcctccggataatgtga

KEGG   Homo sapiens (human): 57180
Entry
57180             CDS       T01001                                 

Gene name
ACTR3B, ARP11, ARP3BETA
Definition
(RefSeq) actin related protein 3B
  KO
K18584  actin-related protein 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    57180 (ACTR3B)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    57180 (ACTR3B)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    57180 (ACTR3B)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    57180 (ACTR3B)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    57180 (ACTR3B)
   05132 Salmonella infection
    57180 (ACTR3B)
   05131 Shigellosis
    57180 (ACTR3B)
   05135 Yersinia infection
    57180 (ACTR3B)
   05100 Bacterial invasion of epithelial cells
    57180 (ACTR3B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    57180 (ACTR3B)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    57180 (ACTR3B)
   04147 Exosome [BR:hsa04147]
    57180 (ACTR3B)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    57180 (ACTR3B)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     57180 (ACTR3B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   57180 (ACTR3B)
  Exosomal proteins of other body fluids (saliva and urine)
   57180 (ACTR3B)
  Exosomal proteins of bladder cancer cells
   57180 (ACTR3B)
SSDB
Motif
Pfam: Actin MreB_Mbl FtsA KilA-N Robl_LC7 ALP_N
Other DBs
NCBI-GeneID: 57180
NCBI-ProteinID: NP_065178
HGNC: 17256
Ensembl: ENSG00000133627
Vega: OTTHUMG00000151463
Pharos: Q9P1U1(Tbio)
UniProt: Q9P1U1 Q59GD5
LinkDB
Position
7q36.1-q36.2
AA seq 418 aa
MAGSLPPCVVDCGTGYTKLGYAGNTEPQFIIPSCIAIRESAKVVDQAQRRVLRGVDDLDF
FIGDEAIDKPTYATKWPIRHGIIEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTP
ENREYLAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPV
AEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVK
EFAKYDVDPRKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVV
DEVIQNCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRVVDARLRLSEELSGGRIKP
KPVEVQVVTHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVFGVMS
NT seq 1257 nt   +upstreamnt  +downstreamnt
atggcaggctccctgcctccctgcgtggtggactgtggcaccgggtataccaagcttggc
tacgcaggcaacactgagccccagttcattattccttcatgtattgccatcagagagtca
gcaaaggtagttgaccaagctcaaaggagagtgttgaggggagttgatgaccttgacttt
ttcataggagatgaagccatcgataaacctacatatgctacaaagtggccgatacgacat
ggaatcattgaagactgggatcttatggaaaggttcatggagcaagtggtttttaaatat
cttcgagctgaacctgaggaccattattttttaatgacagaacctccactcaatacacca
gaaaacagagagtatcttgcagaaattatgtttgaatcatttaacgtaccaggactctac
attgcagttcaggcagtgctggccttggcggcatcttggacatctcgacaagtgggtgaa
cgtacgttaacggggatagtcattgacagcggagatggagtcacccatgttatcccagtg
gcagaaggttatgtaattggaagctgcatcaaacacatcccgattgcaggtagagatatt
acgtatttcattcaacagctgctaagggagagggaggtgggaatccctcctgagcagtca
ctggagaccgcaaaagccattaaggagaaatactgttacatttgccccgatatagtcaag
gaatttgccaagtatgatgtggatccccggaagtggatcaaacagtacacgggtatcaat
gcgatcaaccagaagaagtttgttatagacgttggttacgaaagattcctgggacctgaa
atattctttcacccggagtttgccaacccagactttatggagtccatctcagatgttgtt
gatgaagtaatacagaactgccccatcgatgtgcggcgcccgctgtataagaatgtcgta
ctctcaggaggctccaccatgttcagggatttcggacgccgactgcagagggatttgaag
agagtggtggatgctaggctgaggctcagcgaggagctcagcggcgggaggatcaagccg
aagcctgtggaggtccaggtggtcacgcatcacatgcagcgctacgccgtgtggttcgga
ggctccatgctggcctcgactcccgagttctttcaggtctgccacaccaagaaggactat
gaagagtacgggcccagcatctgccgccacaaccccgtctttggagtcatgtcctag

KEGG   Homo sapiens (human): 653857
Entry
653857            CDS       T01001                                 

Gene name
ACTR3C, ARP11
Definition
(RefSeq) actin related protein 3C
  KO
K18584  actin-related protein 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    653857 (ACTR3C)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    653857 (ACTR3C)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    653857 (ACTR3C)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    653857 (ACTR3C)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    653857 (ACTR3C)
   05132 Salmonella infection
    653857 (ACTR3C)
   05131 Shigellosis
    653857 (ACTR3C)
   05135 Yersinia infection
    653857 (ACTR3C)
   05100 Bacterial invasion of epithelial cells
    653857 (ACTR3C)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    653857 (ACTR3C)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    653857 (ACTR3C)
   04147 Exosome [BR:hsa04147]
    653857 (ACTR3C)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    653857 (ACTR3C)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     653857 (ACTR3C)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   653857 (ACTR3C)
  Exosomal proteins of other body fluids (saliva and urine)
   653857 (ACTR3C)
  Exosomal proteins of bladder cancer cells
   653857 (ACTR3C)
SSDB
Motif
Pfam: Actin FtsA KilA-N Robl_LC7
Other DBs
NCBI-GeneID: 653857
NCBI-ProteinID: NP_001157930
HGNC: 37282
Ensembl: ENSG00000106526
Vega: OTTHUMG00000158323
Pharos: Q9C0K3(Tdark)
UniProt: Q9C0K3
LinkDB
Position
7q36.1
AA seq 210 aa
MFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSC
IKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKEFAKYDVDP
QKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPDSMESISDVVDEVIQNCPI
DVRRPLYKMEQIPLSYPQGHGFHPLSPPFH
NT seq 633 nt   +upstreamnt  +downstreamnt
atgttcgaatcatttaacgttccaggactctacattgcagttcaggcagtgctggccttg
gcggcatcttggacatctcgacaagtgggtgaacgtacattaacggggatagtcattgac
agcggagatggagtcacccatgttatcccagtggcagaaggttatgtaattggaagctgc
atcaaacacatcccgattgcaggtagagatattacgtatttcattcaacagctgctaagg
gagagggaggtgggaatccctcctgagcagtcactggagaccgcaaaagccattaaggag
aaatactgttacatttgccccgatatagtcaaggaatttgccaagtatgatgtggatccc
cagaagtggatcaaacagtacacgggtatcaatgcgatcaaccagaagaagtttgttata
gacgttggttacgaaagattcctgggacctgaaatattctttcacccggagtttgccaac
ccagactctatggagtccatctcagatgttgttgatgaagtaatacagaactgccccatc
gatgtgcggcgtccgctgtataagatggaacaaattccactgagctatcctcaaggtcac
ggattccatcctctgtcacctccatttcattga

KEGG   Homo sapiens (human): 81873
Entry
81873             CDS       T01001                                 

Gene name
ARPC5L, ARC16-2
Definition
(RefSeq) actin related protein 2/3 complex subunit 5 like
  KO
K05754  actin related protein 2/3 complex, subunit 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    81873 (ARPC5L)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    81873 (ARPC5L)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    81873 (ARPC5L)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    81873 (ARPC5L)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    81873 (ARPC5L)
   05132 Salmonella infection
    81873 (ARPC5L)
   05131 Shigellosis
    81873 (ARPC5L)
   05135 Yersinia infection
    81873 (ARPC5L)
   05100 Bacterial invasion of epithelial cells
    81873 (ARPC5L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    81873 (ARPC5L)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    81873 (ARPC5L)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    81873 (ARPC5L)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     81873 (ARPC5L)
SSDB
Motif
Pfam: P16-Arc Utp12
Other DBs
NCBI-GeneID: 81873
NCBI-ProteinID: NP_112240
HGNC: 23366
Ensembl: ENSG00000136950
Vega: OTTHUMG00000020660
Pharos: Q9BPX5(Tdark)
UniProt: Q9BPX5 A0A024R897 B3KPC7
LinkDB
Position
9q33.3
AA seq 153 aa
MARNTLSSRFRRVDIDEFDENKFVDEQEEAAAAAAEPGPDPSEVDGLLRQGDMLRAFHAA
LRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGVDLLMKYIYKGFEKPT
ENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV
NT seq 462 nt   +upstreamnt  +downstreamnt
atggcccggaacacgctgtcctcgcgcttccgccgggtggacatcgacgaatttgacgag
aacaaatttgtggacgagcaggaggaggcggcggcggcggcggcggagccaggcccggac
ccgagcgaggtggacgggctcctgcggcaaggggacatgcttcgggcattccatgcagcc
ttgcggaactctcccgtcaacaccaagaatcaagctgtgaaggagcgagcccagggcgtg
gtgctgaaagtgctcacaaacttcaagagcagtgagattgagcaggctgtgcagtcactg
gacagaaacggcgttgacttgttaatgaagtacatttataaaggctttgagaagcccaca
gaaaatagcagcgcagtgttactccagtggcacgaaaaggccttagcagtaggaggacta
ggctccattataagagttcttacagcaagaaagactgtttaa

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