KEGG   Homo sapiens (human): 10096
Entry
10096             CDS       T01001                                 

Gene name
ACTR3, ARP3
Definition
(RefSeq) actin related protein 3
  KO
K18584  actin-related protein 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06135  Cytoskeletal regulation (viruses)
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10096 (ACTR3)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10096 (ACTR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    10096 (ACTR3)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    10096 (ACTR3)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10096 (ACTR3)
   05132 Salmonella infection
    10096 (ACTR3)
   05131 Shigellosis
    10096 (ACTR3)
   05135 Yersinia infection
    10096 (ACTR3)
   05100 Bacterial invasion of epithelial cells
    10096 (ACTR3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10096 (ACTR3)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10096 (ACTR3)
   04147 Exosome [BR:hsa04147]
    10096 (ACTR3)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    10096 (ACTR3)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     10096 (ACTR3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   10096 (ACTR3)
  Exosomal proteins of other body fluids (saliva and urine)
   10096 (ACTR3)
  Exosomal proteins of bladder cancer cells
   10096 (ACTR3)
SSDB
Motif
Pfam: Actin MreB_Mbl ALP_N FtsA Robl_LC7
Other DBs
NCBI-GeneID: 10096
NCBI-ProteinID: NP_005712
OMIM: 604222
HGNC: 170
Ensembl: ENSG00000115091
Vega: OTTHUMG00000153497
Pharos: P61158(Tbio)
UniProt: P61158 A0A024RAI1
LinkDB
Position
2q14.1
AA seq 418 aa
MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDF
FIGDEAIEKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTP
ENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPV
AEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVK
EFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVV
DEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKP
KPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS
NT seq 1257 nt   +upstreamnt  +downstreamnt
atggcgggacggctgccggcctgtgtggtggactgtggcacggggtatacaaaactagga
tatgctggaaatacagaaccacagtttatcatcccttcctgtattgctattaaggagtca
gcaaaagtgggtgatcaagctcaaaggagggtgatgaaaggtgttgatgacctagacttc
ttcattggtgatgaagcaatagaaaaacctacatatgcaacaaagtggccaatccgccat
ggtatagttgaagattgggacttaatggaaaggtttatggagcaagtgatctttaaatat
ttaagggcagaacctgaagaccattattttcttttgactgaacctccattgaatactcca
gaaaacagggaatatactgctgaaataatgtttgagtccttcaatgttccaggcttgtac
attgctgtgcaggctgttcttgccttagctgcatcttggacctcaagacaagtaggagaa
cggacgttgaccggtacggtaatagacagtggagatggtgtcactcatgtcattcctgtg
gctgaagggtatgtgattggcagctgtattaaacacattccaatcgcaggacgagatata
acatattttattcagcaactgctgagagaccgagaagtaggaatccctccagaacaatcc
ttggaaactgctaaggcagtaaaggagcgctatagttatgtctgcccagatttagtaaaa
gaatttaacaagtatgatacagatgggtcaaaatggattaaacagtatactggaatcaat
gctatctcaaagaaagagttttctatcgatgttggttatgagagatttttgggacctgaa
atcttttttcatccagagtttgctaatccagactttacacaacctatctcagaagttgta
gatgaagtaattcagaattgtcctattgatgtcagacgtcctctctacaagaatattgtc
ctctctggaggttcaaccatgttcagggactttggacgtcgcttgcaaagagatttgaaa
agaactgtagatgcccggctgaaattaagtgaggaattgagtggtggtagattgaagcca
aaacctattgatgtacaagtcattacacaccacatgcagcgatatgcagtttggtttgga
ggatcaatgctggcttccacgcctgagttctaccaagtatgccacaccaaaaaggattat
gaagaaattggacctagcatttgtcgtcacaatccagtgtttggagtcatgtcgtaa

KEGG   Homo sapiens (human): 10097
Entry
10097             CDS       T01001                                 

Gene name
ACTR2, ARP2
Definition
(RefSeq) actin related protein 2
  KO
K17260  actin-related protein 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06135  Cytoskeletal regulation (viruses)
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10097 (ACTR2)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10097 (ACTR2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    10097 (ACTR2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    10097 (ACTR2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10097 (ACTR2)
   05132 Salmonella infection
    10097 (ACTR2)
   05131 Shigellosis
    10097 (ACTR2)
   05135 Yersinia infection
    10097 (ACTR2)
   05100 Bacterial invasion of epithelial cells
    10097 (ACTR2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10097 (ACTR2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10097 (ACTR2)
   04147 Exosome [BR:hsa04147]
    10097 (ACTR2)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    10097 (ACTR2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     10097 (ACTR2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   10097 (ACTR2)
  Exosomal proteins of other body fluids (saliva and urine)
   10097 (ACTR2)
  Exosomal proteins of bladder cancer cells
   10097 (ACTR2)
SSDB
Motif
Pfam: Actin
Other DBs
NCBI-GeneID: 10097
NCBI-ProteinID: NP_005713
OMIM: 604221
HGNC: 169
Ensembl: ENSG00000138071
Vega: OTTHUMG00000129540
Pharos: P61160(Tbio)
UniProt: P61160
LinkDB
Position
2p14
AA seq 394 aa
MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDE
ASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNR
EKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTR
RLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVL
VESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKH
IVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAV
LADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR
NT seq 1185 nt   +upstreamnt  +downstreamnt
atggacagccagggcaggaaggtggtggtgtgcgacaacggcaccgggtttgtgaagtgt
ggatatgcaggctctaactttccagaacacatcttcccagctttggttggaagacctatt
atcagatcaaccaccaaagtgggaaacattgaaatcaaggatcttatggttggtgatgag
gcaagtgaattacgatcaatgttagaagttaactaccctatggaaaatggcatagtacga
aattgggatgacatgaaacacctgtgggactacacatttggaccagagaaacttaatata
gataccagaaattgtaaaatcttactcacagaacctcctatgaacccaaccaaaaacaga
gagaagattgtagaggtaatgtttgaaacttaccagttttccggtgtatatgtagccatc
caggcagttctgactttgtacgctcaaggtttattgactggtgtagtggtagactctgga
gatggtgtgactcacatttgcccagtatatgaaggcttttctctccctcatcttaccagg
agactggatattgctgggagggatataactagatatcttatcaagctacttctgttgcga
ggatacgccttcaaccactctgctgattttgaaacggttcgcatgattaaagaaaaactg
tgttacgtgggatataatattgagcaagagcagaaactggccttagaaaccacagtatta
gttgaatcttatacactcccagatggacgtatcatcaaagttgggggagagagatttgaa
gcaccagaagctttatttcagcctcacttgatcaatgttgaaggagttggtgttgctgaa
ttgctttttaacacaattcaggcagctgacattgataccagatctgaattctacaaacac
attgtgctttctggagggtctactatgtatcctggcctgccatcacggttggaacgagaa
cttaaacagctttacttagaacgagttttgaagggtgatgtggaaaaactttctaaattt
aagatccgcattgaagacccaccccgcagaaagcacatggtattcctgggtggtgcagtt
ctagcggatatcatgaaagacaaagacaacttttggatgacccgacaagagtaccaagaa
aagggtgtccgtgtgctagagaaacttggtgtgactgttcgataa

KEGG   Homo sapiens (human): 57180
Entry
57180             CDS       T01001                                 

Gene name
ACTR3B, ARP11, ARP3BETA
Definition
(RefSeq) actin related protein 3B
  KO
K18584  actin-related protein 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    57180 (ACTR3B)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    57180 (ACTR3B)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    57180 (ACTR3B)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    57180 (ACTR3B)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    57180 (ACTR3B)
   05132 Salmonella infection
    57180 (ACTR3B)
   05131 Shigellosis
    57180 (ACTR3B)
   05135 Yersinia infection
    57180 (ACTR3B)
   05100 Bacterial invasion of epithelial cells
    57180 (ACTR3B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    57180 (ACTR3B)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    57180 (ACTR3B)
   04147 Exosome [BR:hsa04147]
    57180 (ACTR3B)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    57180 (ACTR3B)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     57180 (ACTR3B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   57180 (ACTR3B)
  Exosomal proteins of other body fluids (saliva and urine)
   57180 (ACTR3B)
  Exosomal proteins of bladder cancer cells
   57180 (ACTR3B)
SSDB
Motif
Pfam: Actin MreB_Mbl FtsA KilA-N Robl_LC7 ALP_N
Other DBs
NCBI-GeneID: 57180
NCBI-ProteinID: NP_065178
HGNC: 17256
Ensembl: ENSG00000133627
Vega: OTTHUMG00000151463
Pharos: Q9P1U1(Tbio)
UniProt: Q9P1U1 Q59GD5
LinkDB
Position
7q36.1-q36.2
AA seq 418 aa
MAGSLPPCVVDCGTGYTKLGYAGNTEPQFIIPSCIAIRESAKVVDQAQRRVLRGVDDLDF
FIGDEAIDKPTYATKWPIRHGIIEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTP
ENREYLAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPV
AEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVK
EFAKYDVDPRKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVV
DEVIQNCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRVVDARLRLSEELSGGRIKP
KPVEVQVVTHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVFGVMS
NT seq 1257 nt   +upstreamnt  +downstreamnt
atggcaggctccctgcctccctgcgtggtggactgtggcaccgggtataccaagcttggc
tacgcaggcaacactgagccccagttcattattccttcatgtattgccatcagagagtca
gcaaaggtagttgaccaagctcaaaggagagtgttgaggggagttgatgaccttgacttt
ttcataggagatgaagccatcgataaacctacatatgctacaaagtggccgatacgacat
ggaatcattgaagactgggatcttatggaaaggttcatggagcaagtggtttttaaatat
cttcgagctgaacctgaggaccattattttttaatgacagaacctccactcaatacacca
gaaaacagagagtatcttgcagaaattatgtttgaatcatttaacgtaccaggactctac
attgcagttcaggcagtgctggccttggcggcatcttggacatctcgacaagtgggtgaa
cgtacgttaacggggatagtcattgacagcggagatggagtcacccatgttatcccagtg
gcagaaggttatgtaattggaagctgcatcaaacacatcccgattgcaggtagagatatt
acgtatttcattcaacagctgctaagggagagggaggtgggaatccctcctgagcagtca
ctggagaccgcaaaagccattaaggagaaatactgttacatttgccccgatatagtcaag
gaatttgccaagtatgatgtggatccccggaagtggatcaaacagtacacgggtatcaat
gcgatcaaccagaagaagtttgttatagacgttggttacgaaagattcctgggacctgaa
atattctttcacccggagtttgccaacccagactttatggagtccatctcagatgttgtt
gatgaagtaatacagaactgccccatcgatgtgcggcgcccgctgtataagaatgtcgta
ctctcaggaggctccaccatgttcagggatttcggacgccgactgcagagggatttgaag
agagtggtggatgctaggctgaggctcagcgaggagctcagcggcgggaggatcaagccg
aagcctgtggaggtccaggtggtcacgcatcacatgcagcgctacgccgtgtggttcgga
ggctccatgctggcctcgactcccgagttctttcaggtctgccacaccaagaaggactat
gaagagtacgggcccagcatctgccgccacaaccccgtctttggagtcatgtcctag

KEGG   Homo sapiens (human): 653857
Entry
653857            CDS       T01001                                 

Gene name
ACTR3C, ARP11
Definition
(RefSeq) actin related protein 3C
  KO
K18584  actin-related protein 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    653857 (ACTR3C)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    653857 (ACTR3C)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    653857 (ACTR3C)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    653857 (ACTR3C)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    653857 (ACTR3C)
   05132 Salmonella infection
    653857 (ACTR3C)
   05131 Shigellosis
    653857 (ACTR3C)
   05135 Yersinia infection
    653857 (ACTR3C)
   05100 Bacterial invasion of epithelial cells
    653857 (ACTR3C)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    653857 (ACTR3C)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    653857 (ACTR3C)
   04147 Exosome [BR:hsa04147]
    653857 (ACTR3C)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    653857 (ACTR3C)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     653857 (ACTR3C)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   653857 (ACTR3C)
  Exosomal proteins of other body fluids (saliva and urine)
   653857 (ACTR3C)
  Exosomal proteins of bladder cancer cells
   653857 (ACTR3C)
SSDB
Motif
Pfam: Actin FtsA KilA-N Robl_LC7
Other DBs
NCBI-GeneID: 653857
NCBI-ProteinID: NP_001157930
HGNC: 37282
Ensembl: ENSG00000106526
Vega: OTTHUMG00000158323
Pharos: Q9C0K3(Tdark)
UniProt: Q9C0K3
LinkDB
Position
7q36.1
AA seq 210 aa
MFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSC
IKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKEFAKYDVDP
QKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPDSMESISDVVDEVIQNCPI
DVRRPLYKMEQIPLSYPQGHGFHPLSPPFH
NT seq 633 nt   +upstreamnt  +downstreamnt
atgttcgaatcatttaacgttccaggactctacattgcagttcaggcagtgctggccttg
gcggcatcttggacatctcgacaagtgggtgaacgtacattaacggggatagtcattgac
agcggagatggagtcacccatgttatcccagtggcagaaggttatgtaattggaagctgc
atcaaacacatcccgattgcaggtagagatattacgtatttcattcaacagctgctaagg
gagagggaggtgggaatccctcctgagcagtcactggagaccgcaaaagccattaaggag
aaatactgttacatttgccccgatatagtcaaggaatttgccaagtatgatgtggatccc
cagaagtggatcaaacagtacacgggtatcaatgcgatcaaccagaagaagtttgttata
gacgttggttacgaaagattcctgggacctgaaatattctttcacccggagtttgccaac
ccagactctatggagtccatctcagatgttgttgatgaagtaatacagaactgccccatc
gatgtgcggcgtccgctgtataagatggaacaaattccactgagctatcctcaaggtcac
ggattccatcctctgtcacctccatttcattga

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