KEGG   Homo sapiens (human): 10319Help
Entry
10319             CDS       T01001                                 

Gene name
LAMC3, OCCM
Definition
(RefSeq) laminin subunit gamma 3
  KO
K06247  laminin, gamma 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    10319 (LAMC3)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    10319 (LAMC3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    10319 (LAMC3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    10319 (LAMC3)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    10319 (LAMC3)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    10319 (LAMC3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    10319 (LAMC3)
   05145 Toxoplasmosis
    10319 (LAMC3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Laminin_EGF Laminin_N Laminin_B
Motif
Other DBs
NCBI-GeneID: 10319
NCBI-ProteinID: NP_006050
OMIM: 604349
HGNC: 6494
Ensembl: ENSG00000050555
Vega: OTTHUMG00000020819
Pharos: Q9Y6N6(Tbio)
UniProt: Q9Y6N6 Q8N2D6
LinkDB All DBs
Position
9q34.12
AA seq 1575 aa AA seqDB search
MAAAALLLGLALLAPRAAGAGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGSPPED
FCPHVGAAGAGAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNI
TLRLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLR
PGEDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDR
LNTFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTD
CERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTA
GPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFH
SLSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSC
FCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEEEL
TAPEKFLGDQRFSYGQPLILTFRVPPGDSPLPVQLRLEGTGLALSLRHSSLSGPQDAGHP
REVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSAR
PGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTG
ICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPG
QRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTG
DHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSR
CYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIK
GCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYALV
KEEAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLLPGAREAFLEQM
MSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEEILHAAAILASLE
IPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSYALLWNLLEGRVA
LETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQQVGADTAPYLALLASPGALP
QKSRAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQ
ASSSVQAATVTVMGARTLLADLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQA
ERMLGNAAPLSSSAKKKGREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQA
SQQVLASEARRQELEEAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTHQA
PAQALNETQWALERLRLQLGSPGSLQRKLSLLEQESQQQELQIQGFESDLAEIRADKQNL
EAILHSLPENCASWQ
NT seq 4728 nt NT seq  +upstreamnt  +downstreamnt
atggcggcggctgcgcttctgctggggctggcgctgctggcaccgcgggcggccggcgcg
ggcatgggcgcgtgctatgacggcgcagggcgcccgcagcgctgcctgccggtgttcgag
aacgcggcgtttgggcggctcgcccaggcctcgcacacgtgcggcagcccgcccgaggac
ttctgtccccacgtgggcgccgcgggcgcgggggctcattgccagcgctgcgacgccgcc
gacccccagcgccaccacaacgcctcctacctcaccgacttccacagccaggacgagagc
acctggtggcagagcccgtccatggccttcggcgtgcagtaccccacctcggtcaacatc
accctccgcctagggaaggcttatgagatcacgtatgtgaggctgaagttccacaccagt
cgccctgagagctttgccatctacaagcgcagccgcgccgacggcccatgggagccctac
cagttctacagcgcctcctgccagaagacctacggccggcccgagggccagtacctgcgc
cccggcgaggacgagcgcgtggccttctgcacctctgagttcagcgacatctccccgctg
agtggcggcaacgtggccttctccaccctggagggccggcccagcgcctacaacttcgag
gagagccctgggctgcaggagtgggtcaccagcaccgaactcctcatctctctagaccgg
ctcaacacgtttggggacgacatcttcaaggaccccaaggtgctccagtcctactattat
gccgtgtccgacttctctgtgggcggcaggtgcaagtgcaacgggcatgccagcgagtgc
ggccccgacgtggcaggccagttggcctgccggtgccagcacaacaccaccggcacagac
tgtgagcgctgcctgcccttcttccaggaccgcccgtgggcccggggcaccgccgaggct
gcccacgagtgtctgccctgcaactgcagtggccgctccgaggaatgcacgtttgatcgg
gagctcttccgcagcacaggccacggcgggcgctgtcaccactgccgtgaccacacagct
gggccacactgtgagcgctgtcaggagaatttctatcactgggacccgcggatgccatgc
cagccctgtgactgccagtcggcaggctccctacacctccagtgcgatgacacaggcacc
tgcgcctgcaagcccacggtgactggctggaagtgtgaccgctgtctgcccgggttccac
tcgctcagtgagggaggctgcagaccctgcacttgcaatcccgctggcagcctggacacc
tgtgacccccgcagtgggcgctgcccctgcaaagagaatgtggaaggcaacctatgtgac
agatgtcgcccggggacctttaacctgcagccccacaatccagctggctgcagcagctgt
ttctgctatggccactccaaggtgtgcgcgtccactgcccagttccaggtgcatcacatc
ctcagcgatttccaccagggagccgaaggctggtgggccagaagtgtggggggctctgag
caccccccacaatggagcccaaatggggtcctcctgagcccagaagacgaggaggagctc
acagcaccagagaagttcctgggagaccagcggttcagctatgggcagcccctcatactg
accttccgggtgccccccggggactccccactccctgtacagctgaggctggaagggaca
ggcttggccctgtccctgaggcactctagcctgtctggcccccaggatgccgggcatccc
agggaggtagagctcaggttccacctgcaggagacctccgaggacgtggcccctccactg
ccccccttccacttccagcggctcctcgccaacctgaccagcctccgcctccgcgtcagt
cccggccccagccctgccggtccagtgttcctgactgaggtccggctcacatccgcccgg
ccagggctttccccgccagcctcctgggtggagatttgttcatgtcccactggctacacg
ggccagttctgtgaatcctgtgctccgggatacaagagggagatgccacaggggggtccc
tatgccagctgtgtcccctgcacctgtaaccagcatggcacctgtgaccccaacacaggg
atctgtgtctgcagccaccataccgagggcccatcctgtgaacgctgtttgccaggtttc
tatggcaaccctttcgcgggccaagccgacgactgccagccctgtccctgccctggccag
tcggcctgtacgaccatcccagagagccgggaggtggtgtgtacccactgccccccgggc
cagagagggcggcgctgtgaggtctgtgatgatggcttttttggggacccgctggggctc
tttgggcacccccagccctgccaccagtgccagtgtagcgggaacgtggaccccaatgcc
gtgggcaactgtgaccccctgtctggccactgcctgcgctgcctgcacaacaccacgggt
gaccactgtgagcactgtcaggaaggcttctacgggagcgccctggcccctcgacccgca
gacaaatgcatgccttgcagctgtcacccacagggctcggtcagtgagcagatgccctgc
gacccagtgacaggccaatgctcctgcctgcctcatgtgactgcacgggactgcagccgc
tgctaccctggcttcttcgacctccagcctgggaggggctgccggagctgcaagtgtcac
ccactgggctcccaggaggaccagtgccatcccaagactggacagtgcacctgccgccca
ggtgtcacaggccaggcctgtgacaggtgccagctgggtttcttcggcttctccatcaag
ggctgccgggcctgcaggtgctccccactgggcgctgcctcggcccagtgccacgagaac
ggcacatgcgtgtgcaggcctggcttcgagggctacaaatgtgaccgctgccacgacaac
ttcttcctcacggcagacggcacacactgccagcaatgtccgtcctgctacgccctggtg
aaggaggaggcagccaagctgaaggccagactgactttgacggaggggtggctccaaggg
tccgactgtggcagtccctggggaccactagacattctgctgggagaggccccaaggggg
gacgtctaccagggccatcacctgcttccaggggctcgggaagccttcctggagcagatg
atgagcctcgagggtgctgtcaaggccgcccgggagcagctgcagaggctgaacaagggt
gcccgctgtgcccaggccggatcccagaagacctgcacccagctggcagacctggaggca
gtgctggagtcctcggaagaggagattctgcatgcagctgccattctcgcgtctctggag
attcctcaggaaggtcccagtcagccgaccaaatggagccacctggccacagaggcccgt
gccctcgccaggagccacagagacaccgccaccaagatcgcagccactgcttggagggcc
ctgctcgcctccaacaccagctacgcgcttctctggaatctgctggagggaagggtggcc
ctagagacccagcgggacctggaggacaggtaccaggaggtccaggcggcccagaaagca
ctgaggacggctgtggcagaggtgctgcctgaagcggaaagcgtgttggccaccgtgcag
caagttggcgcagatacagccccgtacctggccttgctggcttccccgggagctctgcct
cagaagtcccgggctgaagacctgggcctgaaggcgaaggccctggagaagacagttgca
tcatggcagcacatggccactgaggctgcccgaaccctccagactgctgcccaggcgacg
ctacggcaaacagaacccctcacaaagctgcaccaggaggccagagccgccctgacccag
gcttcctcatctgtccaggctgcgacagtgactgtcatgggagccaggactctgctggct
gatctggaaggaatgaagctgcagtttccccggcccaaggaccaggcggcattgcagagg
aaggcagactccgtcagtgacagactccttgcagacacgagaaagaagaccaagcaggcg
gagaggatgctgggaaacgcggcccctctttcctccagtgccaagaagaagggcagagaa
gcagaggtgttggccaaggacagtgccaagcttgccaaggccttgctgagggagcggaaa
caggcgcaccgccgtgccagcaggctcaccagccagacgcaagccacgctccaacaggcg
tcccagcaggtgctggcgtctgaagcacgcagacaggagctggaggaagctgagcgggtg
ggtgctgggctgagcgagatggagcagcagatccgggaatcgcgtatctcactggagaag
gacatcgagaccttgtcagagctgcttgccaggctggggtcgctggacacccatcaagcc
ccagcccaggccctgaacgagactcagtgggcactagaacgcctgaggctgcagctgggc
tccccggggtccttgcagaggaaactcagtctgctggagcaggaatcccagcagcaggag
ctgcagatccagggcttcgagagtgacctcgccgagatccgcgccgacaaacagaacctg
gaggccattctgcacagcctgcccgagaactgtgccagctggcagtga

KEGG   Homo sapiens (human): 1101Help
Entry
1101              CDS       T01001                                 

Gene name
CHAD, SLRR4A
Definition
(RefSeq) chondroadherin
  KO
K06248  chondroadherin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05165  Human papillomavirus infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1101 (CHAD)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1101 (CHAD)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1101 (CHAD)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1101 (CHAD)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00535 Proteoglycans [BR:hsa00535]
    1101 (CHAD)
Proteoglycans [BR:hsa00535]
 Extracellular matrix (ECM) proteoglycans
  Small leucine-rich proteoglycan (SLRP) family
   class IV
    1101 (CHAD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: LRR_8 LRR_4 LRR_5 LRR_1 LRRNT LRR_9 LRRCT
Motif
Other DBs
NCBI-GeneID: 1101
NCBI-ProteinID: NP_001258
OMIM: 602178
HGNC: 1909
Ensembl: ENSG00000136457
Vega: OTTHUMG00000162129
Pharos: O15335(Tdark)
UniProt: O15335
LinkDB All DBs
Structure
PDB: 

Position
17q21.33
AA seq 359 aa AA seqDB search
MVRPMLLLSLGLLAGLLPALAACPQNCHCHSDLQHVICDKVGLQKIPKVSEKTKLLNLQR
NNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFD
DLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSE
NALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQ
SFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDSLETLALTNN
PWKCTCQLRGLRRWLEAKASRPDATCASPAKFKGQHIRDTDAFRSCKFPTKRSKKAGRH
NT seq 1080 nt NT seq  +upstreamnt  +downstreamnt
atggtccgcccaatgctcttgctcagcctcggcctcctggctggtctgctgccggcgctg
gccgcctgcccccagaactgccactgccacagcgacctgcagcacgtcatctgcgacaag
gtggggctgcagaagatccccaaggtgtcagagaagaccaagctgctcaacctacagcgc
aacaacttcccggtgctggctgccaattcgttccgggccatgccgaacctcgtgtcattg
cacctgcagcactgccagatccgcgaggtggccgccggtgccttccgcggcctcaagcaa
cttatctacttgtacctgtcccataacgacatccgcgtgctgcgcgcaggtgccttcgac
gacctgaccgagctgacctacctctacctggaccacaacaaggtcactgagctgccccgg
gggttgctctccccgctggtcaacctcttcatcttgcagctcaacaacaacaagatccgt
gagctgcgcgcaggcgccttccagggagccaaggacctgcgctggctctacctgtcggaa
aacgcgttgagctccctgcagcccggggccctggacgacgtggagaacctcgccaaattc
cacgtggacaggaaccagctgtccagctacccctcagctgccctgagcaagctacgggtg
gtggaggagctgaagctgtcccacaaccccctgaaaagcatcccggacaatgccttccag
tcctttggcagatacctggagaccctctggctggacaacaccaacctggagaagttctca
gatggtgccttcctgggtgtaaccacgctgaaacacgtccatttggagaacaaccgcttg
aaccagctaccctccaacttccccttcgacagcctggagaccctcgcccttaccaataac
ccctggaagtgtacctgccagctccggggccttcggcggtggctggaagccaaggcctcc
cgcccagatgccacctgtgcctcacctgccaagttcaagggccagcacatccgtgacacg
gacgccttccgcagctgcaagttccccaccaagaggtccaagaaagctggccgccattaa

KEGG   Homo sapiens (human): 1277Help
Entry
1277              CDS       T01001                                 

Gene name
COL1A1, EDSARTH1, EDSC, OI1, OI2, OI3, OI4
Definition
(RefSeq) collagen type I alpha 1 chain
  KO
K06236  collagen, type I, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04611  Platelet activation
hsa04926  Relaxin signaling pathway
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa04974  Protein digestion and absorption
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
Disease
H00506  Osteogenesis imperfecta
H00613  Infantile cortical hyperostosis
H01593  Osteoporosis
H02243  Ehlers-Danlos syndrome arthrochalasia type
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1277 (COL1A1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1277 (COL1A1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1277 (COL1A1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    1277 (COL1A1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    1277 (COL1A1)
  09154 Digestive system
   04974 Protein digestion and absorption
    1277 (COL1A1)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    1277 (COL1A1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1277 (COL1A1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    1277 (COL1A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1277 (COL1A1)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1277 (COL1A1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Collagen COLFI VWC
Motif
Other DBs
NCBI-GeneID: 1277
NCBI-ProteinID: NP_000079
OMIM: 120150
HGNC: 2197
Ensembl: ENSG00000108821
Vega: OTTHUMG00000148674
Pharos: P02452(Tbio)
UniProt: P02452
LinkDB All DBs
Structure
PDB: 

Position
17q21.33
AA seq 1464 aa AA seqDB search
MFSFVDLRLLLLLAATALLTHGQEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPEPCRI
CVCDNGKVLCDDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPR
GPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGP
MGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGR
PGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQ
MGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGP
RGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGP
QGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGL
PGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL
TGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGV
PGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGE
QGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGS
QGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGD
KGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGP
PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGP
AGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGV
VGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGA
EGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGP
VGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGP
RGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSF
LPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCR
DLKMCHSDWKSGEYWIDPNQGCNLDAIKVFCNMETGETCVYPTQPSVAQKNWYISKNPKD
KRHVWFGESMTDGFQFEYGGQGSDPADVAIQLTFLRLMSTEASQNITYHCKNSVAYMDQQ
TGNLKKALLLQGSNEIEIRAEGNSRFTYSVTVDGCTSHTGAWGKTVIEYKTTKTSRLPII
DVAPLDVGAPDQEFGFDVGPVCFL
NT seq 4395 nt NT seq  +upstreamnt  +downstreamnt
atgttcagctttgtggacctccggctcctgctcctcttagcggccaccgccctcctgacg
cacggccaagaggaaggccaagtcgagggccaagacgaagacatcccaccaatcacctgc
gtacagaacggcctcaggtaccatgaccgagacgtgtggaaacccgagccctgccggatc
tgcgtctgcgacaacggcaaggtgttgtgcgatgacgtgatctgtgacgagaccaagaac
tgccccggcgccgaagtccccgagggcgagtgctgtcccgtctgccccgacggctcagag
tcacccaccgaccaagaaaccaccggcgtcgagggacccaagggagacactggcccccga
ggcccaaggggacccgcaggcccccctggccgagatggcatccctggacagcctggactt
cccggaccccccggaccccccggacctcccggaccccctggcctcggaggaaactttgct
ccccagctgtcttatggctatgatgagaaatcaaccggaggaatttccgtgcctggcccc
atgggtccctctggtcctcgtggtctccctggcccccctggtgcacctggtccccaaggc
ttccaaggtccccctggtgagcctggcgagcctggagcttcaggtcccatgggtccccga
ggtcccccaggtccccctggaaagaatggagatgatggggaagctggaaaacctggtcgt
cctggtgagcgtgggcctcctgggcctcagggtgctcgaggattgcccggaacagctggc
ctccctggaatgaagggacacagaggtttcagtggtttggatggtgccaagggagatgct
ggtcctgctggtcctaagggtgagcctggcagccctggtgaaaatggagctcctggtcag
atgggcccccgtggcctgcctggtgagagaggtcgccctggagcccctggccctgctggt
gctcgtggaaatgatggtgctactggtgctgccgggccccctggtcccaccggccccgct
ggtcctcctggcttccctggtgctgttggtgctaagggtgaagctggtccccaagggccc
cgaggctctgaaggtccccagggtgtgcgtggtgagcctggcccccctggccctgctggt
gctgctggccctgctggaaaccctggtgctgatggacagcctggtgctaaaggtgccaat
ggtgctcctggtattgctggtgctcctggcttccctggtgcccgaggcccctctggaccc
cagggccccggcggccctcctggtcccaagggtaacagcggtgaacctggtgctcctggc
agcaaaggagacactggtgctaagggagagcctggccctgttggtgttcaaggaccccct
ggccctgctggagaggaaggaaagcgaggagctcgaggtgaacccggacccactggcctg
cccggaccccctggcgagcgtggtggacctggtagccgtggtttccctggcgcagatggt
gttgctggtcccaagggtcccgctggtgaacgtggttctcctggccctgctggccccaaa
ggatctcctggtgaagctggtcgtcccggtgaagctggtctgcctggtgccaagggtctg
actggaagccctggcagccctggtcctgatggcaaaactggcccccctggtcccgccggt
caagatggtcgccccggacccccaggcccacctggtgcccgtggtcaggctggtgtgatg
ggattccctggacctaaaggtgctgctggagagcccggcaaggctggagagcgaggtgtt
cccggaccccctggcgctgtcggtcctgctggcaaagatggagaggctggagctcaggga
ccccctggccctgctggtcccgctggcgagagaggtgaacaaggccctgctggctccccc
ggattccagggtctccctggtcctgctggtcctccaggtgaagcaggcaaacctggtgaa
cagggtgttcctggagaccttggcgcccctggcccctctggagcaagaggcgagagaggt
ttccctggcgagcgtggtgtgcaaggtccccctggtcctgctggtccccgaggggccaac
ggtgctcccggcaacgatggtgctaagggtgatgctggtgcccctggagctcccggtagc
cagggcgcccctggccttcagggaatgcctggtgaacgtggtgcagctggtcttccaggg
cctaagggtgacagaggtgatgctggtcccaaaggtgctgatggctctcctggcaaagat
ggcgtccgtggtctgactggccccattggtcctcctggccctgctggtgcccctggtgac
aagggtgaaagtggtcccagcggccctgctggtcccactggagctcgtggtgcccccgga
gaccgtggtgagcctggtccccccggccctgctggctttgctggcccccctggtgctgac
ggccaacctggtgctaaaggcgaacctggtgatgctggtgctaaaggcgatgctggtccc
cctggccctgccggacccgctggaccccctggccccattggtaatgttggtgctcctgga
gccaaaggtgctcgcggcagcgctggtccccctggtgctactggtttccctggtgctgct
ggccgagtcggtcctcctggcccctctggaaatgctggaccccctggccctcctggtcct
gctggcaaagaaggcggcaaaggtccccgtggtgagactggccctgctggacgtcctggt
gaagttggtccccctggtccccctggccctgctggcgagaaaggatcccctggtgctgat
ggtcctgctggtgctcctggtactcccgggcctcaaggtattgctggacagcgtggtgtg
gtcggcctgcctggtcagagaggagagagaggcttccctggtcttcctggcccctctggt
gaacctggcaaacaaggtccctctggagcaagtggtgaacgtggtccccctggtcccatg
ggcccccctggattggctggaccccctggtgaatctggacgtgagggggctcctggtgcc
gaaggttcccctggacgagacggttctcctggcgccaagggtgaccgtggtgagaccggc
cccgctggaccccctggtgctcctggtgctcctggtgcccctggccccgttggccctgct
ggcaagagtggtgatcgtggtgagactggtcctgctggtcccgccggtcctgtcggccct
gttggcgcccgtggccccgccggaccccaaggcccccgtggtgacaagggtgagacaggc
gaacagggcgacagaggcataaagggtcaccgtggcttctctggcctccagggtccccct
ggccctcctggctctcctggtgaacaaggtccctctggagcctctggtcctgctggtccc
cgaggtccccctggctctgctggtgctcctggcaaagatggactcaacggtctccctggc
cccattgggccccctggtcctcgcggtcgcactggtgatgctggtcctgttggtcccccc
ggccctcctggacctcctggtccccctggtcctcccagcgctggtttcgacttcagcttc
ctgccccagccacctcaagagaaggctcacgatggtggccgctactaccgggctgatgat
gccaatgtggttcgtgaccgtgacctcgaggtggacaccaccctcaagagcctgagccag
cagatcgagaacatccggagcccagagggcagccgcaagaaccccgcccgcacctgccgt
gacctcaagatgtgccactctgactggaagagtggagagtactggattgaccccaaccaa
ggctgcaacctggatgccatcaaagtcttctgcaacatggagactggtgagacctgcgtg
taccccactcagcccagtgtggcccagaagaactggtacatcagcaagaaccccaaggac
aagaggcatgtctggttcggcgagagcatgaccgatggattccagttcgagtatggcggc
cagggctccgaccctgccgatgtggccatccagctgaccttcctgcgcctgatgtccacc
gaggcctcccagaacatcacctaccactgcaagaacagcgtggcctacatggaccagcag
actggcaacctcaagaaggccctgctcctccagggctccaacgagatcgagatccgcgcc
gagggcaacagccgcttcacctacagcgtcactgtcgatggctgcacgagtcacaccgga
gcctggggcaagacagtgattgaatacaaaaccaccaagacctcccgcctgcccatcatc
gatgtggcccccttggacgttggtgccccagaccaggaattcggcttcgacgttggccct
gtctgcttcctgtaa

KEGG   Homo sapiens (human): 1278Help
Entry
1278              CDS       T01001                                 

Gene name
COL1A2, EDSARTH2, EDSCV, OI4
Definition
(RefSeq) collagen type I alpha 2 chain
  KO
K06236  collagen, type I, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04611  Platelet activation
hsa04926  Relaxin signaling pathway
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa04974  Protein digestion and absorption
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
Disease
H00506  Osteogenesis imperfecta
H01593  Osteoporosis
H02241  Ehlers-Danlos syndrome cardiac valvular type
H02243  Ehlers-Danlos syndrome arthrochalasia type
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1278 (COL1A2)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1278 (COL1A2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1278 (COL1A2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    1278 (COL1A2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    1278 (COL1A2)
  09154 Digestive system
   04974 Protein digestion and absorption
    1278 (COL1A2)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    1278 (COL1A2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1278 (COL1A2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    1278 (COL1A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1278 (COL1A2)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1278 (COL1A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Collagen COLFI
Motif
Other DBs
NCBI-GeneID: 1278
NCBI-ProteinID: NP_000080
OMIM: 120160
HGNC: 2198
Ensembl: ENSG00000164692
Vega: OTTHUMG00000148675
Pharos: P08123(Tbio)
UniProt: P08123 A0A0S2Z3H5
LinkDB All DBs
Position
7q21.3
AA seq 1366 aa AA seqDB search
MLSFVDTRTLLLLAVTLCLATCQSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTG
PPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEP
GEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIR
GHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSV
GPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNP
GANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNK
GEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPP
GSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPI
GPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQ
GGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAA
GPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEP
GLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPA
GPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDG
GPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPP
GFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIA
GPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAA
GAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLP
GLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIR
GPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRPKDYEVDATLK
SLNNQIETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAIKVYCDFSTG
ETCIRAQPENIPAKNWYRSSKDKKHVWLGETINAGSQFEYNVEGVTSKEMATQLAFMRLL
ANYASQNITYHCKNSIAYMDEETGNLKKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKK
TNEWGKTIIEYKTNKPSRLPFLDIAPLDIGGADQEFFVDIGPVCFK
NT seq 4101 nt NT seq  +upstreamnt  +downstreamnt
atgctcagctttgtggatacgcggactttgttgctgcttgcagtaaccttatgcctagca
acatgccaatctttacaagaggaaactgtaagaaagggcccagccggagatagaggacca
cgtggagaaaggggtccaccaggccccccaggcagagatggtgaagatggtcccacaggc
cctcctggtccacctggtcctcctggcccccctggtctcggtgggaactttgctgctcag
tatgatggaaaaggagttggacttggccctggaccaatgggcttaatgggacctagaggc
ccacctggtgcagctggagccccaggccctcaaggtttccaaggacctgctggtgagcct
ggtgaacctggtcaaactggtcctgcaggtgctcgtggtccagctggccctcctggcaag
gctggtgaagatggtcaccctggaaaacccggacgacctggtgagagaggagttgttgga
ccacagggtgctcgtggtttccctggaactcctggacttcctggcttcaaaggcattagg
ggacacaatggtctggatggattgaagggacagcccggtgctcctggtgtgaagggtgaa
cctggtgcccctggtgaaaatggaactccaggtcaaacaggagcccgtgggcttcctggt
gagagaggacgtgttggtgcccctggcccagctggtgcccgtggcagtgatggaagtgtg
ggtcccgtgggtcctgctggtcccattgggtctgctggccctccaggcttcccaggtgcc
cctggccccaagggtgaaattggagctgttggtaacgctggtcctgctggtcccgccggt
ccccgtggtgaagtgggtcttccaggcctctccggccccgttggacctcctggtaatcct
ggagcaaacggccttactggtgccaagggtgctgctggccttcccggcgttgctggggct
cccggcctccctggaccccgcggtattcctggccctgttggtgctgccggtgctactggt
gccagaggacttgttggtgagcctggtccagctggctccaaaggagagagcggtaacaag
ggtgagcccggctctgctgggccccaaggtcctcctggtcccagtggtgaagaaggaaag
agaggccctaatggggaagctggatctgccggccctccaggacctcctgggctgagaggt
agtcctggttctcgtggtcttcctggagctgatggcagagctggcgtcatgggccctcct
ggtagtcgtggtgcaagtggccctgctggagtccgaggacctaatggagatgctggtcgc
cctggggagcctggtctcatgggacccagaggtcttcctggttcccctggaaatatcggc
cccgctggaaaagaaggtcctgtcggcctccctggcatcgacggcaggcctggcccaatt
ggcccagctggagcaagaggagagcctggcaacattggattccctggacccaaaggcccc
actggtgatcctggcaaaaacggtgataaaggtcatgctggtcttgctggtgctcggggt
gctccaggtcctgatggaaacaatggtgctcagggacctcctggaccacagggtgttcaa
ggtggaaaaggtgaacagggtccccctggtcctccaggcttccagggtctgcctggcccc
tcaggtcccgctggtgaagttggcaaaccaggagaaaggggtctccatggtgagtttggt
ctccctggtcctgctggtccaagaggggaacgcggtcccccaggtgagagtggtgctgcc
ggtcctactggtcctattggaagccgaggtccttctggacccccagggcctgatggaaac
aagggtgaacctggtgtggttggtgctgtgggcactgctggtccatctggtcctagtgga
ctcccaggagagaggggtgctgctggcatacctggaggcaagggagaaaagggtgaacct
ggtctcagaggtgaaattggtaaccctggcagagatggtgctcgtggtgctcctggtgct
gtaggtgcccctggtcctgctggagccacaggtgaccggggcgaagctggggctgctggt
cctgctggtcctgctggtcctcggggaagccctggtgaacgtggtgaggtcggtcctgct
ggccccaatggatttgctggtcctgctggtgctgctggtcaacctggtgctaaaggagaa
agaggagccaaagggcctaagggtgaaaacggtgttgttggtcccacaggccccgttgga
gctgctggcccagctggtccaaatggtccccccggtcctgctggaagtcgtggtgatgga
ggcccccctggtatgactggtttccctggtgctgctggacggactggtcccccaggaccc
tctggtatttctggccctcctggtccccctggtcctgctgggaaagaagggcttcgtggt
cctcgtggtgaccaaggtccagttggccgaactggagaagtaggtgcagttggtccccct
ggcttcgctggtgagaagggtccctctggagaggctggtactgctggacctcctggcact
ccaggtcctcagggtcttcttggtgctcctggtattctgggtctccctggctcgagaggt
gaacgtggtctaccaggtgttgctggtgctgtgggtgaacctggtcctcttggcattgcc
ggccctcctggggcccgtggtcctcctggtgctgtgggtagtcctggagtcaacggtgct
cctggtgaagctggtcgtgatggcaaccctgggaacgatggtcccccaggtcgcgatggt
caacccggacacaagggagagcgcggttaccctggcaatattggtcccgttggtgctgca
ggtgcacctggtcctcatggccccgtgggtcctgctggcaaacatggaaaccgtggtgaa
actggtccttctggtcctgttggtcctgctggtgctgttggcccaagaggtcctagtggc
ccacaaggcattcgtggcgataagggagagcccggtgaaaaggggcccagaggtcttcct
ggcttaaagggacacaatggattgcaaggtctgcctggtatcgctggtcaccatggtgat
caaggtgctcctggctccgtgggtcctgctggtcctaggggccctgctggtccttctggc
cctgctggaaaagatggtcgcactggacatcctggtacagttggacctgctggcattcga
ggccctcagggtcaccaaggccctgctggcccccctggtccccctggccctcctggacct
ccaggtgtaagcggtggtggttatgactttggttacgatggagacttctacagggctgac
cagcctcgctcagcaccttctctcagacccaaggactatgaagttgatgctactctgaag
tctctcaacaaccagattgagacccttcttactcctgaaggctctagaaagaacccagct
cgcacatgccgtgacttgagactcagccacccagagtggagcagtggttactactggatt
gaccctaaccaaggatgcactatggatgctatcaaagtatactgtgatttctctactggc
gaaacctgtatccgggcccaacctgaaaacatcccagccaagaactggtataggagctcc
aaggacaagaaacacgtctggctaggagaaactatcaatgctggcagccagtttgaatat
aatgtagaaggagtgacttccaaggaaatggctacccaacttgccttcatgcgcctgctg
gccaactatgcctctcagaacatcacctaccactgcaagaacagcattgcatacatggat
gaggagactggcaacctgaaaaaggctgtcattctacagggctctaatgatgttgaactt
gttgctgagggcaacagcaggttcacttacactgttcttgtagatggctgctctaaaaag
acaaatgaatggggaaagacaatcattgaatacaaaacaaataagccatcacgcctgccc
ttccttgatattgcacctttggacatcggtggtgctgaccaggaattctttgtggacatt
ggcccagtctgtttcaaataa

KEGG   Homo sapiens (human): 1280Help
Entry
1280              CDS       T01001                                 

Gene name
COL2A1, ANFH, AOM, COL11A3, SEDC, STL1
Definition
(RefSeq) collagen type II alpha 1 chain
  KO
K19719  collagen, type II, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04974  Protein digestion and absorption
hsa05165  Human papillomavirus infection
Disease
H00445  Osteoarthritis with mild chondrodysplasia
H00476  Multiple epiphyseal dysplasia
H00519  Spondyloepiphyseal dysplasia congenita
H00520  Type II collagenopathies
H00805  Vitreoretinal degeneration
H01526  Legg-Calve-Perthes Disease
H01529  Avascular necrosis of femoral head
H01709  Glucocorticoid-induced osteonecrosis
H02066  Achondrogenesis type II
H02070  Kniest dysplasia
H02071  Czech dysplasia
H02072  Stickler syndrome
H02187  Spondyloepimetaphyseal dysplasia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1280 (COL2A1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1280 (COL2A1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1280 (COL2A1)
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    1280 (COL2A1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1280 (COL2A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1280 (COL2A1)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1280 (COL2A1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Collagen COLFI VWC
Motif
Other DBs
NCBI-GeneID: 1280
NCBI-ProteinID: NP_001835
OMIM: 120140
HGNC: 2200
Ensembl: ENSG00000139219
Vega: OTTHUMG00000149896
Pharos: P02458(Tbio)
UniProt: P02458
LinkDB All DBs
Structure
PDB: 

Position
12q13.11
AA seq 1487 aa AA seqDB search
MIRLGAPQTLVLLTLLVAAVLRCQGQDVQEAGSCVQDGQRYNDKDVWKPEPCRICVCDTG
TVLCDDIICEDVKDCLSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKG
PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFA
AQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMG
PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKG
EAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG
PAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKG
SAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQG
APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAG
PKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPG
VMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPG
PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG
LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG
KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG
ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG
AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPG
DDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPG
PVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAG
PTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQG
LPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAG
PPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDATLK
SLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMETG
ETCVYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRL
LSTEGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTK
HTGKWGKTVIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVCFL
NT seq 4464 nt NT seq  +upstreamnt  +downstreamnt
atgattcgcctcggggctccccagacgctggtgctgctgacgctgctcgtcgccgctgtc
cttcggtgtcagggccaggatgtccaggaggctggcagctgtgtgcaggatgggcagagg
tataatgataaggatgtgtggaagccggagccctgccggatctgtgtctgtgacactggg
actgtcctctgcgacgacataatctgtgaagacgtgaaagactgcctcagccctgagatc
cccttcggagagtgctgccccatctgcccaactgacctcgccactgccagtgggcaacca
ggaccaaagggacagaaaggagaacctggagacatcaaggatattgtaggacccaaagga
cctcctgggcctcagggacctgcaggggaacaaggacccagaggggatcgtggtgacaaa
ggtgaaaaaggtgcccctggacctcgtggcagagatggagaacctgggacccctggaaat
cctggcccccctggtcctcccggcccccctggtccccctggtcttggtggaaactttgct
gcccagatggctggaggatttgatgaaaaggctggtggcgcccagttgggagtaatgcaa
ggaccaatgggccccatgggacctcgaggacctccaggccctgcaggtgctcctgggcct
caaggatttcaaggcaatcctggtgaacctggtgaacctggtgtctctggtcccatgggt
ccccgtggtcctcctggtccccctggaaagcctggtgatgatggtgaagctggaaaacct
ggaaaagctggtgaaaggggtccgcctggtcctcagggtgctcgtggtttcccaggaacc
ccaggccttcctggtgtcaaaggtcacagaggttatccaggcctggacggtgctaaggga
gaggcgggtgctcctggtgtgaagggtgagagtggttccccgggtgagaacggatctccg
ggcccaatgggtcctcgtggcctgcctggtgaaagaggacggactggccctgctggcgct
gcgggtgcccgaggcaacgatggtcagccaggccccgcagggcctccgggtcctgtcggt
cctgctggtggtcctggcttccctggtgctcctggagccaagggtgaagccggccccact
ggtgcccgtggtcctgaaggtgctcaaggtcctcgcggtgaacctggtactcctgggtcc
cctgggcctgctggtgcctccggtaaccctggaacagatggaattcctggagccaaagga
tctgctggtgctcctggcattgctggtgctcctggcttccctgggccacggggccctcct
ggccctcaaggtgcaactggtcctctgggcccgaaaggtcagacgggtgaacctggtatt
gctggcttcaaaggtgaacaaggccccaagggagaacctggccctgctggcccccaggga
gcccctggacccgctggtgaagaaggcaagagaggtgcccgtggagagcctggtggcgtt
gggcccatcggtccccctggagaaagaggtgctcccggcaaccgcggtttcccaggtcaa
gatggtctggcaggtcccaagggagcccctggagagcgagggcccagtggtcttgctggc
cccaagggagccaacggtgaccctggccgtcctggagaacctggccttcctggagcccgg
ggtctcactggccgccctggtgatgctggtcctcaaggcaaagttggcccttctggagcc
cctggtgaagatggtcgtcctggacctccaggtcctcagggggctcgtgggcagcctggt
gtcatgggtttccctggccccaaaggtgccaacggtgagcctggcaaagctggtgagaag
ggactgcctggtgctcctggtctgaggggtcttcctggcaaagatggtgagacaggtgct
gcaggaccccctggccctgctggacctgctggtgaacgaggcgagcagggtgctcctggg
ccatctgggttccagggacttcctggccctcctggtcccccaggtgaaggtggaaaacca
ggtgaccagggtgttcccggtgaagctggagcccctggcctcgtgggtcccaggggtgaa
cgaggtttcccaggtgaacgtggctctcccggtgcccagggcctccagggtccccgtggc
ctccccggcactcctggcactgatggtcccaaaggtgcatctggcccagcaggcccccct
ggggctcagggccctccaggtcttcagggaatgcctggcgagaggggagcagctggtatc
gctgggcccaaaggcgacaggggtgacgttggtgagaaaggccctgagggagcccctgga
aaggatggtggacgaggcctgacaggtcccattggcccccctggcccagctggtgctaat
ggcgagaagggagaagttggacctcctggtcctgcaggaagtgctggtgctcgtggcgct
ccgggtgaacgtggagagactgggccccccggaccagcgggatttgctgggcctcctggt
gctgatggccagcctggggccaagggtgagcaaggagaggccggccagaaaggcgatgct
ggtgcccctggtcctcagggcccctctggagcacctgggcctcagggtcctactggagtg
actggtcctaaaggagcccgaggtgcccaaggccccccgggagccactggattccctgga
gctgctggccgcgttggacccccaggctccaatggcaaccctggaccccctggtccccct
ggtccttctggaaaagatggtcccaaaggtgctcgaggagacagcggcccccctggccga
gctggtgaacccggcctccaaggtcctgctggaccccctggcgagaagggagagcctgga
gatgacggtccctctggtgccgaaggtccaccaggtccccagggtctggctggtcagaga
ggcatcgtcggtctgcctgggcaacgtggtgagagaggattccctggcttgcctggcccg
tcgggtgagcccggcaagcagggtgctcctggagcatctggagacagaggtcctcctggc
cccgtgggtcctcctggcctgacgggtcctgcaggtgaacctggacgagagggaagcccc
ggtgctgatggcccccctggcagagatggcgctgctggagtcaagggtgatcgtggtgag
actggtgctgtgggagctcctggagcccctgggccccctggctcccctggccccgctggt
ccaactggcaagcaaggagacagaggagaagctggtgcacaaggccccatgggaccctca
ggaccagctggagcccggggaatccagggtcctcaaggccccagaggtgacaaaggagag
gctggagagcctggcgagagaggcctgaagggacaccgtggcttcactggtctgcagggt
ctgcccggccctcctggtccttctggagaccaaggtgcttctggtcctgctggtccttct
ggccctagaggtcctcctggccccgtcggtccctctggcaaagatggtgctaatggaatc
cctggccccattgggcctcctggtccccgtggacgatcaggcgaaaccggccctgctggt
cctcctggaaatcctggaccccctggtcctccaggtccccctggccctggcatcgacatg
tccgcctttgctggcttaggcccgagagagaagggccccgaccccctgcagtacatgcgg
gccgaccaggcagccggtggcctgagacagcatgacgccgaggtggatgccacactcaag
tccctcaacaaccagattgagagcatccgcagccccgagggctcccgcaagaaccctgct
cgcacctgcagagacctgaaactctgccaccctgagtggaagagtggagactactggatt
gaccccaaccaaggctgcaccttggacgccatgaaggttttctgcaacatggagactggc
gagacttgcgtctaccccaatccagcaaacgttcccaagaagaactggtggagcagcaag
agcaaggagaagaaacacatctggtttggagaaaccatcaatggtggcttccatttcagc
tatggagatgacaatctggctcccaacactgccaacgtccagatgaccttcctacgcctg
ctgtccacggaaggctcccagaacatcacctaccactgcaagaacagcattgcctatctg
gacgaagcagctggcaacctcaagaaggccctgctcatccagggctccaatgacgtggag
atccgggcagagggcaatagcaggttcacgtacactgccctgaaggatggctgcacgaaa
cataccggtaagtggggcaagactgttatcgagtaccggtcacagaagacctcacgcctc
cccatcattgacattgcacccatggacataggagggcccgagcaggaattcggtgtggac
atagggccggtctgcttcttgtaa

KEGG   Homo sapiens (human): 1282Help
Entry
1282              CDS       T01001                                 

Gene name
COL4A1, BSVD, BSVD1, RATOR
Definition
(RefSeq) collagen type IV alpha 1 chain
  KO
K06237  collagen, type IV, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04926  Relaxin signaling pathway
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa04974  Protein digestion and absorption
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Disease
H00579  Hereditary angiopathy with nephropathy, aneurysms, and muscle cramps (HANAC)
H00839  Porencephaly
H00877  Brain small vessel disease with hemorrhage
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1282 (COL4A1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1282 (COL4A1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1282 (COL4A1)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    1282 (COL4A1)
  09154 Digestive system
   04974 Protein digestion and absorption
    1282 (COL4A1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1282 (COL4A1)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    1282 (COL4A1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    1282 (COL4A1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1282 (COL4A1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    1282 (COL4A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1282 (COL4A1)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1282 (COL4A1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   1282 (COL4A1)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1282 (COL4A1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Collagen C4
Motif
Other DBs
NCBI-GeneID: 1282
NCBI-ProteinID: NP_001836
OMIM: 120130
HGNC: 2202
Ensembl: ENSG00000187498
Vega: OTTHUMG00000017342
Pharos: P02462(Tbio)
UniProt: P02462
LinkDB All DBs
Structure
PDB: 

Position
13q34
AA seq 1669 aa AA seqDB search
MGPRLSVWLLLLPAALLLHEEHSRAAAKGGCAGSGCGKCDCHGVKGQKGERGLPGLQGVI
GFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPP
GIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGI
PGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPP
GVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGS
PGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGP
KGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPG
PPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPG
PQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLK
GDKGDPGFPGQPGMPGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDT
GPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFP
GPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNG
LPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGI
RGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPG
PKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPG
LPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIG
PIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPG
TPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGE
KGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGT
PGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSP
GIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPG
IDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKG
LPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPK
GQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTP
SVDHGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTM
PFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAV
HSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRG
TCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT
NT seq 5010 nt NT seq  +upstreamnt  +downstreamnt
atggggccccggctcagcgtctggctgctgctgctgcccgccgcccttctgctccacgag
gagcacagccgggccgctgcgaagggtggctgtgctggctctggctgtggcaaatgtgac
tgccatggagtgaagggacaaaagggtgaaagaggcctcccggggttacaaggtgtcatt
gggtttcctggaatgcaaggacctgaggggccacagggaccaccaggacaaaagggtgat
actggagaaccaggactacctggaacaaaagggacaagaggacctccgggagcatctggc
taccctggaaacccaggacttcccggaattcctggccaagacggcccgccaggcccccca
ggtattccaggatgcaatggcacaaagggggagagagggccgctcgggcctcctggcttg
cctggtttcgctggaaatcccggaccaccaggcttaccagggatgaagggtgatccaggt
gagatacttggccatgtgcccgggatgctgttgaaaggtgaaagaggatttcccggaatc
ccagggactccaggcccaccaggactgccagggcttcaaggtcctgttgggcctccagga
tttaccggaccaccaggtcccccaggccctcccggccctccaggtgaaaagggacaaatg
ggcttaagttttcaaggaccaaaaggtgacaagggtgaccaaggggtcagtgggcctcca
ggagtaccaggacaagctcaagttcaagaaaaaggagacttcgccaccaagggagaaaag
ggccaaaaaggtgaacctggatttcaggggatgccaggggtcggagagaaaggtgaaccc
ggaaaaccaggacccagaggcaaacccggaaaagatggtgacaaaggggaaaaagggagt
cccggttttcctggtgaacccgggtacccaggactcataggccgccagggcccgcaggga
gaaaagggtgaagcaggtcctcctggcccacctggaattgttataggcacaggacctttg
ggagaaaaaggagagaggggctaccctggaactccggggccaagaggagagccaggccca
aaaggtttcccaggactaccaggccaacccggacctccaggcctccctgtacctgggcag
gctggtgcccctggcttccctggtgaaagaggagaaaaaggtgaccgaggatttcctggt
acatctctgccaggaccaagtggaagagatgggctcccgggtcctcctggttcccctggg
ccccctgggcagcctggctacacaaatggaattgtggaatgtcagcccggacctccaggt
gaccagggtcctcctggaattccagggcagccaggatttataggcgaaattggagagaaa
ggtcaaaaaggagagagttgcctcatctgtgatatagacggatatcgggggcctcccggg
ccacagggacccccgggagaaataggtttcccagggcagccaggggccaagggcgacaga
ggtttgcctggcagagatggtgttgcaggagtgccaggccctcaaggtacaccagggctg
ataggccagccaggagccaagggggagcctggtgagttttatttcgacttgcggctcaaa
ggtgacaaaggagacccaggctttccaggacagcccggcatgccagggagagcgggttct
cctggaagagatggccatccgggtcttcctggccccaagggctcgccgggttctgtagga
ttgaaaggagagcgtggcccccctggaggagttggattcccaggcagtcgtggtgacacc
ggcccccctgggcctccaggatatggtcctgctggtcccattggtgacaaaggacaagca
ggctttcctggaggccctggatccccaggcctgccaggtccaaagggtgaaccaggaaaa
attgttcctttaccaggcccccctggagcagaaggactgccggggtccccaggcttccca
ggtccccaaggagaccgaggctttcccggaaccccaggaaggccaggcctgccaggagag
aagggcgctgtgggccagccaggcattggatttccagggccccccggccccaaaggtgtt
gacggcttacctggagacatggggccaccggggactccaggtcgcccgggatttaatggc
ttacctgggaacccaggtgtgcagggccagaagggagagcctggagttggtctaccggga
ctcaaaggtttgccaggtcttcccggcattcctggcacacccggggagaaggggagcatt
ggggtaccaggcgttcctggagaacatggagcgatcggaccccctgggcttcaggggatc
agaggtgaaccgggacctcctggattgccaggctccgtggggtctccaggagttccagga
ataggcccccctggagctaggggtccccctggaggacagggaccaccggggttgtcaggc
cctcctggaataaaaggagagaagggtttccccggattccctggactggacatgccgggc
cctaaaggagataaaggggctcaaggactccctggcataacgggacagtcggggctccct
ggccttcctggacagcagggggctcctgggattcctgggtttccaggttccaagggagaa
atgggcgtcatggggacccccgggcagccgggctcaccaggaccagtgggtgctcctgga
ttaccgggtgaaaaaggggaccatggctttccgggctcctcaggacccaggggagaccct
ggcttgaaaggtgataagggggatgtcggtctccctggcaagcctggctccatggataag
gtggacatgggcagcatgaagggccagaaaggagaccaaggagagaaaggacaaattgga
ccaattggtgagaagggatcccgaggagaccctgggaccccaggagtgcctggaaaggac
gggcaggcaggacagcctgggcagccaggacctaaaggtgatccaggtataagtggaacc
ccaggtgctccaggacttccgggaccaaaaggatctgttggtggaatgggcttgccagga
acacctggagagaaaggtgtgcctggcatccctggcccacaaggttcacctggcttacct
ggagacaaaggtgcaaaaggagagaaagggcaggcaggcccacctggcataggcatccca
gggctgcgaggtgaaaagggagatcaagggatagcgggtttcccaggaagccctggagag
aagggagaaaaaggaagcattgggatcccaggaatgccagggtccccaggccttaaaggg
tctcccgggagtgttggctatccaggaagtcctgggctacctggagaaaaaggtgacaaa
ggcctcccaggattggatggcatccctggtgtcaaaggagaagcaggtcttcctgggact
cctggccccacaggcccagctggccagaaaggggagccaggcagtgatggaatcccgggg
tcagcaggagagaagggtgaaccaggtctaccaggaagaggattcccagggtttccaggg
gccaaaggagacaaaggttcaaagggtgaggtgggtttcccaggattagccgggagccca
ggaattcctggatccaaaggagagcaaggattcatgggtcctccggggccccagggacag
ccggggttaccgggatccccaggccatgccacggaggggcccaaaggagaccgcggacct
cagggccagcctggcctgccaggacttccgggacccatggggcctccagggcttcctggg
attgatggagttaaaggtgacaaaggaaatccaggctggccaggagcacccggtgtccca
gggcccaagggagaccctggattccagggcatgcctggtattggtggctctccaggaatc
acaggctctaagggtgatatggggcctccaggagttccaggatttcaaggtccaaaaggt
cttcctggcctccagggaattaaaggtgatcaaggcgatcaaggcgtcccgggagctaaa
ggtctcccgggtcctcctggccccccaggtccttacgacatcatcaaaggggagcccggg
ctccctggtcctgagggccccccagggctgaaagggcttcagggactgccaggcccgaaa
ggccagcaaggtgttacaggattggtgggtatacctggacctccaggtattcctgggttt
gacggtgcccctggccagaaaggagagatgggacctgccgggcctactggtccaagagga
tttccaggtccaccaggccccgatgggttgccaggatccatggggcccccaggcacccca
tctgttgatcacggcttccttgtgaccaggcatagtcaaacaatagatgacccacagtgt
ccttctgggaccaaaattctttaccacgggtactctttgctctacgtgcaaggcaatgaa
cgggcccatggccaggacttgggcacggccggcagctgcctgcgcaagttcagcacaatg
cccttcctgttctgcaatattaacaacgtgtgcaactttgcatcacgaaatgactactcg
tactggctgtccacccctgagcccatgcccatgtcaatggcacccatcacgggggaaaac
ataagaccatttattagtaggtgtgctgtgtgtgaggcgcctgccatggtgatggccgtg
cacagccagaccattcagatcccaccgtgccccagcgggtggtcctcgctgtggatcggc
tactcttttgtgatgcacaccagcgctggtgcagaaggctctggccaagccctggcgtcc
cccggctcctgcctggaggagtttagaagtgcgccattcatcgagtgtcacggccgtggg
acctgcaattactacgcaaacgcttacagcttttggctcgccaccatagagaggagcgag
atgttcaagaagcctacgccgtccaccttgaaggcaggggagctgcgcacgcacgtcagc
cgctgccaagtctgtatgagaagaacataa

KEGG   Homo sapiens (human): 1284Help
Entry
1284              CDS       T01001                                 

Gene name
COL4A2, BSVD2, ICH, POREN2
Definition
(RefSeq) collagen type IV alpha 2 chain
  KO
K06237  collagen, type IV, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04926  Relaxin signaling pathway
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa04974  Protein digestion and absorption
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Disease
H00839  Porencephaly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1284 (COL4A2)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1284 (COL4A2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1284 (COL4A2)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    1284 (COL4A2)
  09154 Digestive system
   04974 Protein digestion and absorption
    1284 (COL4A2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1284 (COL4A2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    1284 (COL4A2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    1284 (COL4A2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1284 (COL4A2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    1284 (COL4A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1284 (COL4A2)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1284 (COL4A2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   1284 (COL4A2)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1284 (COL4A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Collagen C4
Motif
Other DBs
NCBI-GeneID: 1284
NCBI-ProteinID: NP_001837
OMIM: 120090
HGNC: 2203
Ensembl: ENSG00000134871
Vega: OTTHUMG00000017344
Pharos: P08572(Tbio)
UniProt: P08572 A0A024RDW8
LinkDB All DBs
Structure
PDB: 

Position
13q34
AA seq 1712 aa AA seqDB search
MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGR
GQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIP
GHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERD
RYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKG
EKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGF
PGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKG
ARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPAL
YGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDA
GECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGA
PGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPP
GDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQID
CDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRG
LPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQ
PGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGL
HGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGH
PGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGL
AGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLS
GIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGL
YGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTG
VQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHG
LPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPG
SPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPG
TPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPG
APGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQ
GRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQ
EPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASR
NDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLW
IGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIP
EQSFQGSPSADTLKAGLIRTHISRCQVCMKNL
NT seq 5139 nt NT seq  +upstreamnt  +downstreamnt
atggggagagaccagcgcgcggtggccggccctgccctacggcggtggctgctgctgggg
acagtgaccgtggggttcctcgcccagagcgtcttggcgggtgtgaagaagtttgatgtg
ccgtgtggaggaagagattgcagtgggggctgccagtgctaccctgagaaaggtggacgt
ggtcagcctgggccagtgggcccccaggggtacaatgggccaccaggattacaaggattc
ccgggactgcagggacgtaaaggagacaagggtgaaaggggagcccccggagtaacggga
cccaagggcgacgtgggagcaagaggcgtttctggattccctggtgccgatggaattcct
ggacacccggggcaaggtgggcccaggggaaggccgggctacgatggctgcaacggaacc
cagggagactcaggtccacaggggccccccggctctgaggggttcaccgggcctcccggg
ccccaaggaccaaaagggcagaaaggtgagccttatgcactgcctaaagaggagcgcgac
agatatcggggtgaacctggagagcctggattggtcggtttccagggacctcccggccgc
cctgggcatgtgggacagatgggtccagttggagctccagggagaccaggaccacctgga
ccccctggaccaaaaggacagcaaggcaacagaggacttggtttctacggagttaagggt
gaaaagggtgacgtagggcagccgggacccaacgggattccatcagacaccctccacccc
atcatcgcgcccacaggagtcaccttccacccagatcagtacaagggtgaaaaaggcagt
gagggggaaccaggaataagaggcatttccttgaagggagaagaaggaatcatgggcttt
cctggactgaggggttaccctggcttgagtggtgaaaaaggatcaccaggacagaaggga
agccgaggcctggatggctatcaagggcctgatggaccccggggacccaagggagaagcc
ggagacccagggccccctggactacctgcctactcccctcacccttccctagcaaaaggt
gccagaggtgacccgggattcccaggggcccaaggggagccaggaagccagggtgagcca
ggagacccgggcctcccaggtccccctggcctctccatcggagatggagatcagaggaga
ggcctgccgggtgagatgggacccaagggcttcatcggagaccccggcatccctgcgctc
tacgggggcccacctggacctgatggaaagcgagggcctccaggaccccccgggctccct
ggaccacctggacctgatggcttcctgtttgggctgaaaggagcaaaaggaagagcaggc
ttccctgggcttcccggctcccctggagcccgcggaccaaaggggtggaaaggtgacgct
ggggaatgcagatgtacagaaggcgacgaagctatcaaaggtcttccgggactgccagga
cccaagggcttcgcaggcatcaacggggagccggggaggaaaggggacagaggagacccc
ggccaacacggcctccctgggttcccagggctcaagggagtgcctggcaacattggtgct
cccggacccaaaggagcaaaaggagattccagaacaatcacaaccaaaggtgagcgggga
cagcccggcgtcccaggtgtgcccgggatgaaaggtgacgatggcagcccaggccgcgat
gggctcgatggattccccggcctcccaggccctcccggtgatggcatcaagggccctcca
ggggacccaggctatccaggaatacctggaacgaagggtactccaggagaaatgggcccc
ccaggactgggccttcccggcctcaaaggccaacgtggtttccctggagacgccggctta
cctggaccaccaggcttcctgggccctcctggccccgcagggaccccaggacaaatagat
tgtgacacagatgtgaaaagggccgttggaggtgacagacaggaggccatccagccaggt
tgcataggagggcccaagggattgccaggcctgccaggacccccaggccccacaggtgcc
aaaggcctccgaggaatcccaggcttcgcaggagctgatggaggaccagggcccaggggc
ttgccaggagacgcaggtcgtgaagggttcccaggacccccagggttcataggaccccga
ggatccaaaggtgcagtgggcctccctggcccagatggatccccaggtcccatcggcctg
ccagggccagatgggccccctggggaaaggggcctccctggagaagtcctgggagctcag
cccgggccacggggagatgctggtgtgcctggacagcctgggcttaaaggccttcccgga
gacagaggcccccctggattcagaggaagccaagggatgcctgggatgccagggctgaag
ggccagccaggcctcccaggaccttccggccagccaggcctgtatgggcctccaggactg
catggattcccaggagctcctggccaagaggggcccttggggctgccaggaatcccaggc
cgtgaaggtctgcctggtgatagaggggaccctggggacacaggcgctcctggccctgtg
ggcatgaaaggtctctctggtgacagaggagatgctggcttcacaggggagcaaggccat
ccaggaagccctggatttaaaggaattgatggaatgcctgggacccccgggctaaaagga
gatagaggctcacctgggatggatggtttccaaggcatgcctggactcaaagggagaccc
gggtttccagggagcaaaggcgaggctggatttttcggaatacccggtctgaagggtctg
gctggtgagccaggttttaaaggcagccgaggggaccctgggcccccaggaccacctcct
gtcatcctgccaggaatgaaagacattaaaggagagaaaggagatgaagggcctatgggg
ctgaaaggatacctgggcgcaaaaggtatccaaggaatgccaggcatcccagggctgtca
ggaatccctgggctgcctgggaggcccggccacatcaaaggagtcaagggagacatcgga
gtccccggcatccccggtttgccaggattccctggggtggctggcccccctggaattacg
ggattcccaggattcataggaagccggggtgacaaaggtgccccagggagagcaggcctg
tatggcgagattggcgcgactggtgatttcggtgacatcggggacactataaatttacca
ggaagaccaggcctgaagggggagcggggcaccactggaataccaggtctgaagggattc
tttggagagaagggaacagaaggtgacatcggcttccctgggataacaggcgtgactgga
gtccaaggccctcctggacttaaaggacaaacaggctttccagggctgactgggcctcca
gggtcgcagggagagctggggcggattggactgcctggtggcaaaggagatgatggctgg
ccgggagctccgggcttaccaggttttccgggactccgtgggatccgcggcttacacggc
ttgccaggcaccaagggctttccaggatccccaggttctgacatccacggagacccaggc
ttcccaggccctcctggggaaagaggtgacccaggagaggccaacacccttccaggccct
gtgggagtcccaggacagaaaggagaccaaggagctccaggggaacgaggcccacctggg
agcccaggacttcaggggttcccaggcatcacacccccttccaacatctctggggcacct
ggtgacaaaggggcgccagggatatttggcctgaaaggttatcggggcccaccagggcca
ccaggttctgctgctcttcctggaagcaaaggtgacacagggaacccaggagctccagga
accccagggaccaaaggatgggccggggactccgggccccagggcaggcctggtgtgttt
ggtctcccaggagaaaaagggcccaggggtgaacaaggcttcatggggaacactggaccc
accggggcggtgggcgacagaggccccaagggacccaagggagacccaggattccctggt
gcccccgggactgtgggagcccccgggattgcaggaatcccccagaagattgccgtccaa
ccagggacagtgggtccccaggggaggcgaggcccccctggggcaccgggggagatgggg
ccccagggcccccccggagaaccaggttttcgtggggctccagggaaagctgggccccaa
ggaagaggtggtgtgtctgctgttcccggcttccggggagatgaaggacccataggccac
caggggccgattggccaagaaggtgcaccaggccgtccagggagcccgggcctgccgggt
atgccaggccgcagcgtcagcatcggctacctcctggtgaagcacagccagacggaccag
gagcccatgtgcccagtgggcatgaacaaactctggagtggatacagcctgctgtacttc
gagggccaggagaaggcgcacaaccaggacctggggctggcgggctcctgcctggcgcgg
ttcagcaccatgcccttcctgtactgcaaccctggtgatgtctgctactatgccagccgg
aacgacaagtcctactggctctctaccactgcgccgctgcccatgatgcccgtggccgag
gacgagatcaagccctacatcagccgctgttctgtgtgtgaggccccggccatcgccatc
gcggtccacagtcaggatgtctccatcccacactgcccagctgggtggcggagtttgtgg
atcggatattccttcctcatgcacacggcggcgggagacgaaggcggtggccaatcactg
gtgtcaccgggcagctgtctagaggacttccgcgccacaccattcatcgaatgcaatgga
ggccgcggcacctgccactactacgccaacaagtacagcttctggctgaccaccattccc
gagcagagcttccagggctcgccctccgccgacacgctcaaggccggcctcatccgcaca
cacatcagccgctgccaggtgtgcatgaagaacctgtga

KEGG   Homo sapiens (human): 1285Help
Entry
1285              CDS       T01001                                 

Gene name
COL4A3, ATS2, ATS3
Definition
(RefSeq) collagen type IV alpha 3 chain
  KO
K06237  collagen, type IV, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04926  Relaxin signaling pathway
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa04974  Protein digestion and absorption
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Disease
H00581  Alport syndrome
H00582  Benign familial hematuria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1285 (COL4A3)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1285 (COL4A3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1285 (COL4A3)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    1285 (COL4A3)
  09154 Digestive system
   04974 Protein digestion and absorption
    1285 (COL4A3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1285 (COL4A3)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    1285 (COL4A3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    1285 (COL4A3)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1285 (COL4A3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    1285 (COL4A3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1285 (COL4A3)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1285 (COL4A3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   1285 (COL4A3)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1285 (COL4A3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Collagen C4
Motif
Other DBs
NCBI-GeneID: 1285
NCBI-ProteinID: NP_000082
OMIM: 120070
HGNC: 2204
Ensembl: ENSG00000169031
Vega: OTTHUMG00000149891
Pharos: Q01955(Tbio)
UniProt: Q01955
LinkDB All DBs
Structure
PDB: 

Position
2q36.3
AA seq 1670 aa AA seqDB search
MSARTAPRPQVLLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSP
GQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLV
GVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPG
PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP
PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPG
KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPG
PPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP
GCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCP
YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEK
GETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGD
PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGP
PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSL
GCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPG
TPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD
PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI
GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK
GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM
GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG
KKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPG
LPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP
GLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPG
SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGE
KGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP
PGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPAT
WTTRGFVFTRHSQTTAIPSCPEGTVPLYSGFSFLFVQGNQRAHGQDLGTLGSCLQRFTTM
PFLFCNVNDVCNFASRNDYSYWLSTPALMPMNMAPITGRALEPYISRCTVCEGPAIAIAV
HSQTTDIPPCPHGWISLWKGFSFIMFTSAGSEGTGQALASPGSCLEEFRASPFLECHGRG
TCNYYSNSYSFWLASLNPERMFRKPIPSTVKAGELEKIISRCQVCMKKRH
NT seq 5013 nt NT seq  +upstreamnt  +downstreamnt
atgagcgcccggaccgcccccaggccgcaggtgctcctgctgccgctcctgctggtgctc
ctggcggcggcgcccgcagccagcaagggttgtgtctgtaaagacaaaggccagtgcttc
tgtgacggggccaaaggggagaagggggagaagggctttcctggaccccccggttctcct
ggccagaaaggattcacaggtcctgaaggcttgcctggaccgcagggacccaagggcttt
ccaggacttccaggactcacgggttccaaaggtgtaaggggaataagtggattgccagga
ttttctggttctcctggacttccaggcaccccaggcaataccgggccttacggacttgtc
ggtgtaccaggatgcagtggttctaagggtgagcaggggtttccaggactcccagggaca
ctgggctacccagggatcccgggtgctgctggtttgaaaggacaaaagggtgctcctgct
aaagaagaagatatagaacttgatgcaaaaggcgaccccgggttgccaggggctccagga
ccccagggtttgccaggccctccaggttttcctgggcctgttggcccacctggtcctccg
ggattctttggctttccaggagccatgggacctagaggacctaagggtcacatgggtgaa
agagtgataggacataaaggagagcggggtgtgaaagggttaacaggacccccgggacca
ccaggaacagttattgtgaccctaactggcccagataacagaacggacctcaagggggaa
aagggagacaagggagcaatgggcgagcctggacctcctggaccctcaggactgcctgga
gaatcatatggatctgaaaagggtgctcctggagaccctggcctgcagggaaaacccgga
aaagatggtgttcctggcttccctggaagtgagggagtcaagggcaacaggggtttccct
gggttaatgggtgaagatggcattaagggacagaaaggggacattggccctccaggattt
cgtggtccaacagaatattatgacacataccaggaaaagggagatgaaggcactccaggc
ccaccagggcccagaggagctcgtggcccacaaggtcccagtggtccccccggagttcct
ggaagtcctggatcatcaaggcctggcctcagaggagcccctggatggccaggcctgaaa
ggaagtaaaggggaacgaggccgcccaggaaaggatgccatggggactcctgggtcccca
ggttgtgctggttcaccaggtcttccaggatcaccgggacctccaggaccgccaggtgac
atcgtttttcgcaagggtccacctggagatcacggactgccaggctatctagggtctcca
ggaatcccaggagttgatgggcccaaaggagaaccaggcctcctgtgtacacagtgccct
tatatcccagggcctcccggtctcccaggattgccagggttacatggtgtaaaaggaatc
ccaggaagacaaggcgcagctggcttgaaaggaagcccagggtccccaggaaatacaggt
cttccaggatttccaggtttcccaggtgcccagggtgacccaggacttaaaggagaaaaa
ggtgaaacacttcagcctgaggggcaagtgggtgtcccaggtgacccggggctcagaggc
caacctgggagaaagggcttggatggaattcctggaactccgggagtgaaaggattacca
ggacctaaaggcgaactggctctgagtggtgagaaaggggaccaaggtcctccaggggat
cctggctcccctgggtccccaggacctgcaggaccagctggaccacctggctacggaccc
caaggagaacctggtctccagggcacgcaaggagttcctggagcccccggaccacccgga
gaagccggccctaggggagagctcagtgtttcaacaccagttccaggcccaccaggacct
ccagggccccctggccatcctggcccccaaggtccacctggtatccctggatccctgggg
aaatgtggagatcctggtcttccagggcctgatggtgaaccaggaattccaggaattgga
tttcctgggcctcctggacctaagggagaccaaggttttccaggtacaaaaggatcactg
ggttgtcctggaaaaatgggagagcctgggttacctggaaagccaggcctcccaggagcc
aagggagaaccagcagtagccatgcctggaggaccaggaacaccaggttttccaggagaa
agaggcaattctggggaacatggagaaattggactccctggacttccaggtctccctgga
actccaggaaatgaagggcttgatggaccacgaggagatccagggcagcctggaccacct
ggagaacaaggacccccaggaaggtgcatagagggtcccaggggagcccaaggacttcca
ggcttaaatggattgaaagggcaacaaggcagaagaggtaaaacggggccaaagggagac
ccaggaattccaggcttggatagatcaggatttcctggagaaactggatcaccaggaatt
ccaggtcatcaaggtgaaatgggaccactgggtcaaagaggatatccaggaaatccggga
attttagggccaccaggtgaagatggagtgattgggatgatgggctttcctggagccatt
ggccctccagggccccctgggaacccaggcacaccagggcagagggggagccctggaatt
ccaggagtaaagggccagagaggaaccccaggagccaagggggaacaaggagataaagga
aatcccgggccttcagagatatcccacgtaataggggacaaaggagaaccaggtctcaaa
ggattcgcaggaaatccaggtgagaaaggaaacagaggcgttccagggatgccaggttta
aagggcctcaaaggactacccggaccagcaggaccaccaggccccagaggagatttgggc
agcactgggaatcctggagaaccaggactgcgtggtataccaggaagcatggggaacatg
ggcatgccaggttctaaaggaaaaaggggaactttgggattcccaggtcgagcaggaaga
ccaggcctcccaggtattcatggtctccagggagataagggagagccaggttattcagaa
ggtacaaggccaggaccaccgggaccaacgggggatccaggactgccgggtgatatggga
aagaaaggagaaatggggcaacctggcccacctggacatttggggcctgctggacctgag
ggagcccctggaagtcctggaagtcctggcctcccaggaaagccaggtcctcatggtgat
ttgggttttaaaggaatcaaaggcctcctgggccctccaggaatcagaggccctccaggt
cttccaggatttccaggatctcctggaccaatgggtataagaggtgaccaaggacgtgat
ggaattcctggtccagccggagaaaagggagaaacgggtttattgagggcccctccaggc
ccaagagggaaccctggtgctcaaggagccaaaggagacaggggagccccaggttttcct
ggcctcccgggcagaaaaggggccatgggagatgctggacctcgaggacccacaggcata
gaaggattcccagggccaccaggtctgcccggtgcaattatccctggccagacaggaaat
cgtggtccaccaggctcaagaggaagcccaggtgcgcctggtccccctggacctccaggg
agtcatgtaataggcataaaaggagacaaagggtctatgggccaccctggcccaaaaggt
ccacctggaactgcaggagacatgggaccaccaggtcgtctgggagcaccaggtactcca
ggtcttccaggacccagaggtgatcctggattccaggggtttccaggcgtgaaaggagaa
aagggtaatcctggatttctaggatccattggacctccaggaccaattgggccaaaagga
ccacctggtgtacgtggagaccctggcacacttaagattatctcccttccaggaagccca
gggccacctggcacacctggagaaccagggatgcagggagaacctgggccaccagggcca
cctggaaacctaggaccctgtgggccaagaggtaagccaggcaaggatggaaaaccagga
actcctggaccagctggagaaaaaggcaacaaaggttctaaaggagagccaggaccagct
ggatcagatggattgccaggtttgaaaggaaaacgtggagacagtggatcacctgcaacc
tggacaacgagaggctttgtcttcacccgacacagtcaaaccacagcaattccttcatgt
ccagaggggacagtgccactctacagtgggttttcttttctttttgtacaaggaaatcaa
cgagcccacggacaagaccttggaactcttggcagctgcctgcagcgatttaccacaatg
ccattcttattctgcaatgtcaatgatgtatgtaattttgcatctcgaaatgattattca
tactggctgtcaacaccagctctgatgccaatgaacatggctcccattactggcagagcc
cttgagccttatataagcagatgcactgtttgtgaaggtcctgcgatcgccatagccgtt
cacagccaaaccactgacattcctccatgtcctcacggctggatttctctctggaaagga
ttttcattcatcatgttcacaagtgcaggttctgagggcaccgggcaagcactggcctcc
cctggctcctgcctggaagaattccgagccagcccatttctagaatgtcatggaagagga
acgtgcaactactattcaaattcctacagtttctggctggcttcattaaacccagaaaga
atgttcagaaagcctattccatcaactgtgaaagctggggaattagaaaaaataataagt
cgctgtcaggtgtgcatgaagaaaagacactga

KEGG   Homo sapiens (human): 1286Help
Entry
1286              CDS       T01001                                 

Gene name
COL4A4, ATS2, BFH, CA44
Definition
(RefSeq) collagen type IV alpha 4 chain
  KO
K06237  collagen, type IV, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04926  Relaxin signaling pathway
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa04974  Protein digestion and absorption
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Disease
H00581  Alport syndrome
H00582  Benign familial hematuria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1286 (COL4A4)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1286 (COL4A4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1286 (COL4A4)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    1286 (COL4A4)
  09154 Digestive system
   04974 Protein digestion and absorption
    1286 (COL4A4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1286 (COL4A4)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    1286 (COL4A4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    1286 (COL4A4)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1286 (COL4A4)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    1286 (COL4A4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1286 (COL4A4)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1286 (COL4A4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   1286 (COL4A4)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1286 (COL4A4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Collagen C4
Motif
Other DBs
NCBI-GeneID: 1286
NCBI-ProteinID: NP_000083
OMIM: 120131
HGNC: 2206
Ensembl: ENSG00000081052
Vega: OTTHUMG00000149892
Pharos: P53420(Tbio)
UniProt: P53420
LinkDB All DBs
Structure
PDB: 

Position
2q36.3
AA seq 1690 aa AA seqDB search
MWSLHIVLMRCSFRLTKSLATGPWSLILILFSVQYVYGSGKKYIGPCGGRDCSVCHCVPE
KGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGL
DGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILG
AVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKG
QMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGE
KGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVT
PPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPG
EAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGR
GPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGL
PGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGP
PGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKG
QKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGP
PGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPG
IKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPG
LPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPG
PPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPG
DEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEK
GQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASH
FGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGL
RGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPP
GPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPP
GDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGK
DGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPG
LPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGY
PGGPGPPGPIGDPGPKGFGPGYLGGFLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQE
KAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQRNDRSYWLASAAPLPMMPLSEEAIR
PYVSRCAVCEAPAQAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTGAGDQGGGQALMSPG
SCLEDFRAAPFLECQGRQGTCHFFANKYSFWLTTVKADLQFSSAPAPDTLKESQAQRQKI
SRCQVCVKYS
NT seq 5073 nt NT seq  +upstreamnt  +downstreamnt
atgtggtctctgcacatagtactaatgaggtgctccttcagattgaccaagtccttggcc
acaggtccctggtcacttatactcattctcttttctgtacaatatgtatatgggagtgga
aagaaatacattggtccttgtggaggaagagattgctctgtttgccactgtgttcctgaa
aaggggtctcggggtccaccaggaccaccagggccacagggtccaattggacccctggga
gccccaggacccattgggctttcaggagagaaaggaatgagaggggaccgcggccctcct
ggagcagcaggggacaaaggagataagggtccaactggtgttcctggatttccaggttta
gatggcatacctgggcacccagggcctcctggacccagaggcaaacctggtatgagtggc
cacaatggctcaagaggtgacccagggtttccaggaggaagaggagctcttggcccagga
ggccccctaggccatcctggggaaaagggagaaaaaggaaattcagtgttcattttaggt
gccgttaaaggtattcagggagacagaggggacccaggactgcctggcttaccaggatct
tggggtgcaggaggaccggcaggtcccacaggatatcctggagagccagggttagtggga
cctccgggccaaccagggcgtccaggtttgaagggaaatcccggtgtgggagtaaagggg
caaatgggagacccgggtgaggttggtcagcaaggttctcctggacccaccctgttggta
gagccacctgacttttgtctctataaaggagaaaagggtataaaaggaattcctggaatg
gttggactgccaggaccaccaggacgcaagggagaatctggtattggggcaaaaggagaa
aaaggtattcctggatttccagggcctcggggggatcctggttcctatggatctccaggt
tttccaggattaaagggagaactaggactggttggagatcctgggctatttggattaatt
ggcccaaagggggatcctggaaatcgagggcacccaggaccaccaggtgttttggtgact
ccacctcttccactcaaaggcccaccaggggacccagggttccctggccgctatggagaa
acaggggatgttggaccacctggtcccccaggtctcttgggcagaccaggggaagcctgt
gcaggcatgataggaccccctgggccacaaggatttcctggtcttcctgggcttccagga
gaagctggtattcctgggagacctgattctgctccaggaaaaccagggaagccaggatca
cctggcttgcctggagcaccaggcctgcagggcctcccaggatcaagtgtgatatactgt
agtgttgggaaccccggaccacaaggaataaaaggcaaagttggtcccccaggaggaaga
ggcccaaaaggagaaaaaggaaatgaaggactctgtgcctgtgagcctggacccatgggc
ccccctggccctccaggacttcctgggaggcaggggagtaagggagacttggggctccct
ggctggcttggaacaaaaggtgacccaggacctcctggtgctgaaggacctccagggcta
ccaggaaagcatggtgcctctggaccacctggcaacaaaggggcgaagggtgacatggtt
gtatcaagagttaaagggcacaaaggagaaagaggtcctgatgggcccccaggatttcca
gggcagccaggatcacatggtcgggatggacatgctggagaaaaaggggatccaggacct
ccaggggatcatgaagatgcgaccccaggtggtaaaggatttcctggacctctgggcccc
ccaggcaaagcaggacctgtggggcccccaggactgggatttcctggtccaccaggagag
cgaggccacccaggagttccaggccacccaggtgtgaggggccctgatggcttgaagggt
cagaaaggtgacacaatttcttgcaacgtaacctaccctgggaggcatggccctccaggt
tttgatggacctccaggtccgaagggatttccaggtccccaaggtgcccctgggctgagt
ggttcagatgggcataaaggcagacctggcacaccaggaacagcggaaataccaggtcca
cctggttttcgtggtgacatgggagatccgggttttggaggtgaaaaggggtcctcccct
gttgggcccccaggccctcccggctcaccaggagtgaatggtcagaaaggaatcccggga
gaccctgcatttggtcacctgggacccccgggaaagaggggtctttcaggagtgccaggg
ataaaaggacccagaggtgatccgggatgtccaggggctgaagggccagctggcattcct
ggattcctaggtctcaaaggtcccaaaggcagagagggacatgctgggtttccaggtgtc
ccaggtccacctggccattcctgtgaaagaggtgctccagggataccagggcaaccggga
ctccctgggtatccaggtagcccaggtgctccaggtgggaaaggacagccgggagatgtg
gggcctcccgggccagctggaatgaaaggcctccccggactcccaggacggcctggggca
catggtcccccaggcctcccaggaatcccaggtccctttggagatgatgggctacctggt
cctccaggtccaaagggaccccgggggctgcctggtttcccaggttttcccggagaaaga
ggaaagcctggtgcagagggatgtcctggcgcaaagggagaacctggagagaagggcatg
tctggccttcctggagaccggggactgagaggggccaaaggagccataggacctcccgga
gatgaaggagaaatggctatcatttcacaaaagggaacacctggggaacctggacctcct
ggagatgatggattcccaggagaaagaggtgataaaggaactcccgggatgcaagggaga
agaggagagccgggaagatacggaccacctggatttcacagaggggaacctggtgagaaa
ggtcagccagggcctcctggacccccaggccctccaggctcaactggtctaagagggttc
attggttttccaggacttccaggtgaccagggtgagccaggttctccaggtccccctgga
ttttcaggaattgatggagcaagaggacctaaaggaaacaaaggtgaccctgccagtcac
tttggtccacctggtccaaagggtgagccaggtagccctggatgtccagggcattttgga
gcatccggagagcagggcttgcctggtattcaagggcccagaggatcacctggaaggcca
gggccacctggctcctctggaccaccagggtgcccaggtgatcacgggatgcctgggctg
aggggacagccaggagaaatgggagaccctgggccaagaggcctccagggggatccaggg
ataccaggtcctccgggaataaaaggtccctccggatcacctggcctgaacggcttgcat
ggattgaaaggtcagaaaggaactaaaggtgcttcaggtttgcatgatgtggggccacct
ggtccagtgggaatacctgggctaaaaggggagagaggagaccctgggagcccaggaatc
tctcctccaggtcctcgtggaaagaaaggtcccccaggacccccagggagttcaggacca
cctggtcctgcaggtgccacaggaagagctcctaaggacattcctgacccgggtccacct
ggagatcagggacctcctggtcctgatggcccaagaggagcacctgggcctccaggcctc
cctgggagtgttgaccttctgagaggggagccaggtgactgtggtctaccagggccacca
ggtccccctggcccaccaggccctccaggatacaaaggctttccaggatgtgatggaaaa
gatggccagaaaggaccagtgggattcccgggaccgcagggaccacatggatttcctggg
ccacctggagagaagggtttacctggacctccagggagaaaagggcccactggtcttccg
ggtcccagaggtgaaccggggccacctgcagatgtggatgactgtccccgaatcccaggc
cttcctggggcgccaggcatgagaggaccagaaggagccatggggctccctggaatgaga
ggcccctcaggaccagggtgcaaaggagagcctgggctggatggcaggaggggtgtggat
ggcgtccctgggtctcctgggcctcccggacgtaaaggtgacacaggagaagacggctac
cctggaggaccagggcctcctggtcccattggggatcctgggcccaaagggtttggccct
ggatacctcggtggcttcctcctggttctccacagtcagacggaccaggagcccacctgc
cccctgggcatgcccaggctctggactgggtatagtctgttatacctggaagggcaagag
aaagctcacaatcaagaccttggtctggcagggtcttgccttcccgtatttagcacgctg
ccctttgcctactgcaacatccaccaggtgtgccactatgcccagagaaacgacagatcc
tactggctggccagcgctgcgcccctccccatgatgccactctctgaagaggcgatccgc
ccctatgtcagccgctgtgcggtatgcgaggccccggcccaggcggtggcggtgcacagc
caggaccagtccatccccccatgtccgcagacctggaggagcctctggatcgggtattca
ttcctgatgcacacaggagctggggaccaaggaggagggcaggcccttatgtcacctggc
agctgcctggaagatttcagagcagcaccattccttgaatgccagggccggcagggaact
tgccactttttcgcaaataagtatagcttctggctcacaacggtgaaagcagacttgcag
ttttcctctgctccagcaccagacaccttaaaagaaagccaggcccaacgccagaaaatc
agccggtgccaggtctgcgtgaagtatagctag

KEGG   Homo sapiens (human): 1287Help
Entry
1287              CDS       T01001                                 

Gene name
COL4A5, ASLN, ATS, ATS1, CA54
Definition
(RefSeq) collagen type IV alpha 5 chain
  KO
K06237  collagen, type IV, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04926  Relaxin signaling pathway
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa04974  Protein digestion and absorption
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Disease
H00581  Alport syndrome
H01640  Uterine leiomyoma
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1287 (COL4A5)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1287 (COL4A5)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1287 (COL4A5)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    1287 (COL4A5)
  09154 Digestive system
   04974 Protein digestion and absorption
    1287 (COL4A5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1287 (COL4A5)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    1287 (COL4A5)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    1287 (COL4A5)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1287 (COL4A5)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    1287 (COL4A5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1287 (COL4A5)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1287 (COL4A5)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   1287 (COL4A5)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1287 (COL4A5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Collagen C4
Motif
Other DBs
NCBI-GeneID: 1287
NCBI-ProteinID: NP_000486
OMIM: 303630
HGNC: 2207
Ensembl: ENSG00000188153
Vega: OTTHUMG00000022182
Pharos: P29400(Tbio)
UniProt: P29400 Q49AM6 A7MBN3
LinkDB All DBs
Structure
PDB: 

Position
Xq22.3
AA seq 1685 aa AA seqDB search
MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPG
LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQG
IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG
IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP
PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP
GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN
IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG
PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT
CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF
PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKG
ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT
QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI
PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP
GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHG
IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM
MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL
GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI
GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG
PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG
NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL
SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP
GRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK
GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI
PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP
PGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHG
QDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSIQPF
ISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASPGSC
LEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTRISRCQV
CMKRT
NT seq 5058 nt NT seq  +upstreamnt  +downstreamnt
atgaaactgcgtggagtcagcctggctgccggcttgttcttactggccctgagtctttgg
gggcagcctgcagaggctgcggcttgctatgggtgttctccaggatcaaagtgtgactgc
agtggcataaaaggggaaaagggagagagagggtttccaggtttggaaggacacccagga
ttgcctggatttccaggtccagaagggcctccggggcctcggggacaaaagggtgatgat
ggaattccagggccaccaggaccaaaaggaatcagaggtcctcctggacttcctggattt
ccagggacaccaggtcttcctggaatgccaggccacgatggggccccaggacctcaaggt
attcccggatgcaatggaaccaagggagaacgtggatttccaggcagtcccggttttcct
ggtttacagggtcctccaggaccccctgggatcccaggtatgaagggtgaaccaggtagt
ataattatgtcatcactgccaggaccaaagggtaatccaggatatccaggtcctcctgga
atacaaggcctacctggtcccactggtataccagggccaattggtcccccaggaccacca
ggtttgatgggccctcctggtccaccaggacttccaggacctaaggggaatatgggctta
aatttccagggacccaaaggtgaaaaaggtgagcaaggtcttcagggcccacctgggcca
cctgggcagatcagtgaacagaaaagaccaattgatgtagagtttcagaaaggagatcag
ggacttcctggtgaccgagggcctcctggacctccagggatacgtggtcctccaggtccc
ccaggtggtgagaaaggtgagaagggtgagcaaggagagccaggcaaaagaggtaaacca
ggcaaagatggagaaaatggccaaccaggaattcctggtttgcctggtgatcctggttac
cctggtgaacccggaagggatggtgaaaagggccaaaaaggtgacactggcccacctgga
cctcctggacttgtaattcctagacctgggactggtataactataggagaaaaaggaaac
attgggttgcctgggttgcctggagaaaaaggagagcgaggatttcctggaatacagggt
ccacctggccttcctggacctccaggggctgcagttatgggtcctcctggccctcctgga
tttcctggagaaaggggtcagaaaggtgatgaaggaccacctggaatttccattcctgga
cctcctggacttgacggacagcctggggctcctgggcttccagggcctcctggccctgct
ggccctcacattcctcctagtgatgagatatgtgaaccaggccctccaggccccccagga
tctccaggtgataaaggactccaaggagaacaaggagtgaaaggtgacaaaggtgacact
tgcttcaactgcattggaactggtatttcagggcctccaggtcaacctggtttgccaggt
ctcccaggtcctccaggatctcttggtttccctggacagaaaggggaaaaaggacaagct
ggtgcaactggtcccaaaggattaccaggcattccaggagctccaggtgctccaggcttt
cctggatctaaaggtgaacctggtgatatcctcacttttccaggaatgaagggtgacaaa
ggagagttgggttcccctggagctccagggcttcctggtttacctggcactcctggacag
gatggattgccagggcttcctggcccgaaaggagagcctggtggaattacttttaagggt
gaaagaggtccccctgggaacccaggtttaccaggcctcccagggaatatagggcctatg
ggtccccctggtttcggccctccaggcccagtaggtgaaaaaggcatacaaggtgtggca
ggaaatccaggccagccaggaataccaggtcctaaaggggatccaggtcagactataacc
cagccggggaagcctggcttgcctggtaacccaggcagagatggtgatgtaggtcttcca
ggtgaccctggacttccagggcaaccaggcttgccagggatacctggtagcaaaggagaa
ccaggtatccctggaattgggcttcctggaccacctggtcccaaaggctttcctggaatt
ccaggacctccaggagcacctgggacacctggaagaattggtctagaaggccctcctggg
ccacccggctttccaggaccaaagggtgaaccaggatttgcattacctgggccacctggg
ccaccaggacttccaggtttcaaaggagcacttggtccaaaaggtgatcgtggtttccca
ggacctccgggtcctccaggacgcactggcttagatgggctccctggaccaaaaggtgat
gttggaccaaatggacaacctggaccaatgggacctcctgggctgccaggaataggtgtt
cagggaccaccaggaccaccagggattcctgggccaataggtcaacctggtttacatgga
ataccaggagagaagggggatccaggacctcctggacttgatgttccaggacccccaggt
gaaagaggcagtccagggatccccggagcacctggtcctataggacctccaggatcacca
gggcttccaggaaaagcaggtgcctctggatttccaggtaccaaaggtgaaatgggtatg
atgggacctccaggcccaccaggacctttgggaattcctggcaggagtggtgtacctggt
cttaaaggtgatgatggcttgcagggtcagccaggacttcctggccctacaggagaaaaa
ggtagtaaaggagagcctggccttccaggccctcctggaccaatggatccaaatcttctg
ggctcaaaaggagagaagggggaacctggcttaccaggtatacctggagtttcagggcca
aaaggttatcagggtttgcctggagacccagggcaacctggactgagtggacaacctgga
ttaccaggaccaccaggtcccaaaggtaaccctggtctccctggacagccaggtcttata
ggacctcctggacttaaaggaaccatcggtgatatgggttttccagggcctcagggtgtg
gaagggcctcctggaccttctggagttcctggacaacctggctccccaggattacctgga
cagaaaggcgacaaaggtgatcctggtatttcaagcattggtcttccaggtcttcctggt
ccaaagggtgagcctggtctgcctggatacccagggaaccctggtatcaaaggttctgtg
ggagatcctggtttgcccggattaccaggaacccctggagcaaaaggacaaccaggcctt
cctggattcccaggaaccccaggccctcctggaccaaaaggtattagtggccctcctggg
aaccccggccttccaggagaacctggtcctgtaggtggtggaggtcatcctgggcaacca
gggcctccaggcgaaaaaggcaaacccggtcaagatggtattcctggaccagctggacag
aagggtgaaccaggtcaaccaggctttggaaacccaggaccccctggacttccaggactt
tctggccaaaagggtgatggaggattacctgggattccaggaaatcctggccttccaggt
ccaaagggcgaaccaggctttcacggtttccctggtgtgcagggtcccccaggccctcct
ggttctccgggtccagctctggaaggacctaaaggcaaccctgggccccaaggtcctcct
gggagaccaggtctaccaggtccagaaggtcctccaggtctccctggaaatggaggtatt
aaaggagagaagggaaatccaggccaacctgggctacctggcttgcctggtttgaaagga
gatcaaggaccaccaggactccagggtaatcctggccggccgggtctcaatggaatgaaa
ggagatcctggtctccctggtgttccaggattcccaggcatgaaaggacccagtggagta
cctggatcagctggccctgagggggaaccgggacttattggtcctccaggtcctcctgga
ttacctggtccttcaggacagagtatcataattaaaggagatgctggtcctccaggaatc
cctggccagcctgggctaaagggtctaccaggaccccaaggacctcaaggcttaccaggt
ccaactggccctccaggagatcctggacgcaatggactccctggctttgatggtgcagga
gggcgcaaaggagacccaggtctgccaggacagccaggtacccgtggtttggatggtccc
cctggtccagatggattgcaaggtcccccaggtccccctggaacctcctctgttgcacat
ggatttcttattacacgccacagccagacaacggatgcaccacaatgcccacagggaaca
cttcaggtctatgaaggcttttctctcctgtatgtacaaggaaataaaagagcccacggt
caagacttggggacggctggcagctgccttcgtcgctttagtaccatgcctttcatgttc
tgcaacatcaataatgtttgcaactttgcttcaagaaatgactattcttactggctctct
accccagagcccatgccaatgagcatgcaacccctaaagggccagagcatccagccattc
attagtcgatgtgcagtatgtgaagctccagctgtggtgatcgcagttcacagtcagacg
atccagattccccattgtcctcagggatgggattctctgtggattggttattccttcatg
atgcatacaagtgcaggggcagaaggctcaggtcaagccctagcctcccctggttcctgc
ttggaagagtttcgttcagctcccttcatcgaatgtcatgggaggggtacctgtaactac
tatgccaactcctacagcttttggctggcaactgtagatgtgtcagacatgttcagtaaa
cctcagtcagaaacgctgaaagcaggagacttgaggacacgaattagccgatgtcaagtg
tgcatgaagaggacataa

KEGG   Homo sapiens (human): 1288Help
Entry
1288              CDS       T01001                                 

Gene name
COL4A6, CXDELq22.3, DELXq22.3, DFNX6
Definition
(RefSeq) collagen type IV alpha 6 chain
  KO
K06237  collagen, type IV, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04926  Relaxin signaling pathway
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa04974  Protein digestion and absorption
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Disease
H01209  Deafness, X-linked
H01640  Uterine leiomyoma
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1288 (COL4A6)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1288 (COL4A6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1288 (COL4A6)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    1288 (COL4A6)
  09154 Digestive system
   04974 Protein digestion and absorption
    1288 (COL4A6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1288 (COL4A6)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    1288 (COL4A6)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    1288 (COL4A6)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1288 (COL4A6)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    1288 (COL4A6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1288 (COL4A6)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1288 (COL4A6)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   1288 (COL4A6)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1288 (COL4A6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Collagen C4
Motif
Other DBs
NCBI-GeneID: 1288
NCBI-ProteinID: NP_001838
OMIM: 303631
HGNC: 2208
Ensembl: ENSG00000197565
Vega: OTTHUMG00000022179
Pharos: Q14031(Tbio)
UniProt: Q14031
LinkDB All DBs
Position
Xq22.3
AA seq 1691 aa AA seqDB search
MLINKLWLLLVTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGP
TGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGP
PGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLD
GITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAG
PPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPG
PRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGN
PGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTI
GAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSG
FCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSG
PKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGE
KGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIP
GSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEK
GLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSG
LPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISG
HPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKG
SVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRR
PMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPP
GFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGS
PGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGE
PGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPA
GLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGD
PGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGE
LGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPG
PLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQG
PPGFEGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGMSQLWVGYSLLFVEG
QEKAHNQDLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIPMMPVSQTQ
IPQYISRCSVCEAPSQAIAVHSQDITIPQCPLGWRSLWIGYSFLMHTAAGAEGGGQSLVS
PGSCLEDFRATPFIECSGARGTCHYFANKYSFWLTTVEERQQFGELPVSETLKAGQLHTR
VSRCQVCMKSL
NT seq 5076 nt NT seq  +upstreamnt  +downstreamnt
atgcttataaacaagttgtggctgctcctggttacgttgtgcctgaccgaggaactggca
gcagcgggagagaagtcttatggaaagccatgtgggggccaggactgcagtgggagctgt
cagtgttttcctgagaaaggagcgagaggacgacctggaccaattggaattcaaggccca
acaggtcctcaaggattcactggctctactggtttatcgggattgaaaggagaaaggggt
ttcccaggccttctgggaccttatggaccaaaaggagataagggtcccatgggagttcct
ggctttcttggcatcaatgggattccgggccaccctggacaaccaggccccagaggccca
cctggtctggatggctgtaatggaactcaaggagctgttggatttccaggccctgatggc
tatcctgggcttctcggaccacccgggcttcctggtcagaaaggatcaaaaggtgaccct
gtccttgctccaggtagtttcaaaggaatgaagggggatcctgggctgcctggactggat
ggaatcactggcccacaaggagcacccggatttcctggagctgtaggacctgcaggacca
ccaggattacaaggtcctccagggcctcctggtcctcttggtcctgatgggaatatgggg
ctaggttttcaaggagagaaaggagtcaagggggatgttggcctccctggcccagcagga
cctccaccatctactggagagctggaattcatgggattccccaaagggaagaaaggatcc
aagggtgaaccagggcctaagggttttccaggcataagtggccctccaggcttcccgggc
cttggaactactggagaaaagggagaaaagggagaaaagggaatccctggtttgccagga
cctaggggtcccatgggttcagaaggagtccaaggccctccagggcaacagggcaagaaa
gggaccctgggatttcctgggcttaatggattccaaggaattgagggtcaaaagggtgac
attggcctgccaggcccagatgttttcatcgatatagatggtgctgtgatctcaggtaat
cctggagatcctggtgtacctggcctcccaggccttaaaggagatgaaggcatccaaggc
ctacgtggcccttctggtgtccctggattgccagcattatcaggtgtcccaggagcccta
gggcctcagggatttccagggctgaagggggaccaaggaaacccaggccgtaccacaatt
ggagcagctggcctccctggcagagatggtttgccaggcccaccaggtccaccaggccca
cctagtccagaatttgagactgaaactctacacaacaaagagtcagggttccctggtctc
cgaggagaacaaggtccaaaaggaaacctaggcctcaaaggaataaaaggagactcaggt
ttctgtgcttgtgacggtggtgttcccaacactggaccacccggggaaccaggcccacct
ggtccatggggtctcataggccttccaggccttaaaggagccagaggagatcgaggctct
gggggtgcacagggcccagcaggggctccaggcttagttgggcctctgggtccttcagga
cccaaaggaaagaagggggaaccaattctcagtacaatccaaggaatgccaggagatcgg
ggtgattctggctcccagggcttccgtggtgtaataggagaaccaggcaaggacggagta
ccaggtttaccaggtctgccaggccttccgggtgatggtggacagggcttcccaggtgaa
aaggggttacctggacttcctggtgaaaaaggccatcctggtccacctggcctcccagga
aatgggttaccaggacttcctggaccccgtgggcttcctggagataaaggcaaggatgga
ttaccgggacaacaaggccttcccggatctaagggaatcaccctgccctgtattattcct
gggtcatacggtccatcaggatttccaggcactcccggattcccaggccctaaagggtct
cgaggcctccctgggaccccaggccagcctgggtcaagtggaagtaaaggagagccaggg
agtccaggattggttcatcttcctgaattaccaggatttcctggacctcgtggggagaag
ggcttgcctgggtttcctgggctccctggaaaagatggcttgcctgggatgattggcagt
ccaggcttacctggttccaagggagccactggtgacatctttggtgctgaaaatggtgct
ccgggggaacaaggcctacaaggattaacagggcacaaaggatttcttggagactctggc
cttccaggactcaagggtgtgcacgggaagcctggcttactaggccccaaaggtgagcgg
ggcagccctgggacaccaggacaggtgggacagccaggcaccccaggatctagtggtcca
tatggcatcaagggcaaatctgggctcccaggagcaccaggcttcccaggcatctcagga
catcctggaaagaaaggaacaagaggcaagaaaggtcctcctggatcaattgtaaagaaa
gggctgccagggctaaaaggccttcctggaaatccaggcctagtaggactgaaaggaagc
ccaggctctccaggggtcgctgggttgccagccctctctggacccaagggagagaagggg
tctgttggattcgtaggttttccaggaataccaggtctgcctggtattcctggaacaaga
ggattaaaaggaattccaggatcaactggaaaaatgggaccatctggacgtgctggtact
cctggtgaaaagggagacagaggcaatccggggccagtcggaatacctagtccaagacgt
ccaatgtcaaacctttggctcaaaggagacaaaggctctcaaggctcagccggatccaat
ggatttcctgggccaagaggtgacaaaggagaggctggtcgacctggaccaccaggccta
cctggagctcctggcctcccaggcattatcaaaggagttagtggaaagccagggccccct
ggcttcatgggaatccggggcttacctggcctgaaggggtcctctgggatcacaggtttc
ccaggaatgccaggagaaagtggttcacaaggtatcagagggtcgcctggactcccagga
gcatctggtctcccaggcctgaaaggagacaacggccagacagttgaaatttccggtagc
ccaggacccaagggacagcctggcgaatctggttttaaaggcacaaaaggaagagatgga
ctaataggcaatataggcttccctggaaacaaaggtgaagatggaaaagttggtgtttct
ggagatgttggccttcctggagctccaggatttccaggagttgccggcatgagaggagaa
ccaggacttccaggttcttctggtcaccaaggggcaattgggcctctaggatcccccgga
ttaataggacccaaaggcttccctggatttcctggtttacatggactgaatgggcttccg
ggcaccaagggtacccatggcactccaggacctagtatcaccggtgtgcctgggcctgct
ggtctccctggacccaaaggagaaaaaggatatccaggaattggcatcggagctccaggg
aagccgggcctgagagggcaaaaaggtgatcgaggtttcccaggtctccagggccctgct
ggtctccccggtgccccaggcatctccttgccctcactcatagcaggacagcctggtgac
cccgggcgaccaggcctagatggagaacgaggccgcccaggccccgctggacccccaggt
ccccctgggccatcctcgaatcaaggcgacaccggagaccctggcttccctggaattcct
ggacctaaagggcctaagggagaccaaggaattccaggtttttctggcctccctggagag
ctaggactgaaaggcatgagaggtgagcctggcttcatggggactccaggcaaggttggg
ccacctggagacccaggatttcccggaatgaaggggaaggcagggccaagaggctcttct
ggcctccaaggtgatcctggacaaacaccaactgcagaagctgtccaggttcctcctgga
cccttgggtctaccagggatcgatggcatccctggcctcactggggaccctggggctcaa
ggccctgtaggcctacaaggctccaaaggtttacctggcatccccggtaaagatggcccc
agtgggctcccaggcccacctggggctcttggtgatcctggtctgcctggactgcaaggc
cctccaggatttgaaggagctccagggcagcaaggccccttcgggatgcctggaatgcct
ggccagagcatgagagtgggctacacgttggtaaagcacagccagtcggaacaggtgccc
ccgtgtcccatcgggatgagccagctgtgggtggggtacagcttactgtttgtggagggg
caagagaaagcccacaaccaggacctgggctttgctggctcctgtctgccccgcttcagc
accatgcccttcatctactgcaacatcaacgaggtgtgccactatgccaggcgcaatgat
aaatcttactggctctccactaccgcccctatccccatgatgcccgtcagccagacccag
attccccagtacatcagccgctgctctgtgtgtgaggcaccctcgcaagccattgctgtg
cacagccaggacatcaccatcccgcagtgccccctgggctggcgcagcctctggattggg
tactctttcctcatgcacactgccgctggtgccgagggtggaggccagtccctggtctca
cctggctcctgcctagaggactttcgggccactcctttcatcgaatgcagtggtgcccga
ggcacctgccactactttgcaaacaagtacagtttctggttgaccacagtggaggagagg
cagcagtttggggagttgcctgtgtctgaaacgctgaaagctgggcagctccacactcga
gtcagtcgctgccaggtgtgtatgaaaagcctgtag

KEGG   Homo sapiens (human): 1291Help
Entry
1291              CDS       T01001                                 

Gene name
COL6A1, BTHLM1, OPLL, UCHMD1
Definition
(RefSeq) collagen type VI alpha 1 chain
  KO
K06238  collagen, type VI, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04974  Protein digestion and absorption
hsa05165  Human papillomavirus infection
Disease
H00431  Ossification of the posterior longitudinal ligament of spine
H01340  Bethlem myopathy
H01341  Collagen VI myopathy
H01778  Ullrich disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1291 (COL6A1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1291 (COL6A1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1291 (COL6A1)
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    1291 (COL6A1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1291 (COL6A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1291 (COL6A1)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1291 (COL6A1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   1291 (COL6A1)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1291 (COL6A1)
 Hyaluronan
  Extracellular matrix or blood plasma proteins
   1291 (COL6A1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: VWA Collagen VWA_2 VWA_3 YcaO
Motif
Other DBs
NCBI-GeneID: 1291
NCBI-ProteinID: NP_001839
OMIM: 120220
HGNC: 2211
Ensembl: ENSG00000142156
Vega: OTTHUMG00000090440
Pharos: P12109(Tbio)
UniProt: P12109 A0A384P5H7
LinkDB All DBs
Position
21q22.3
AA seq 1028 aa AA seqDB search
MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVD
KVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAV
KYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAK
HLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIK
NNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM
KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP
KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA
PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD
EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTK
GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDII
MKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYA
GVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPN
NRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPS
QGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASV
GSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL
ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ
EAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQT
VSRKVALG
NT seq 3087 nt NT seq  +upstreamnt  +downstreamnt
atgagggcggcccgtgctctgctgcccctgctgctgcaggcctgctggacagccgcgcag
gatgagccggagaccccgagggccgtggccttccaggactgccccgtggacctgttcttt
gtgctggacacctctgagagcgtggccctgaggctgaagccctacggggccctcgtggac
aaagtcaagtccttcaccaagcgcttcatcgacaacctgagggacaggtactaccgctgt
gaccgaaacctggtgtggaacgcaggcgcgctgcactacagtgacgaggtggagatcatc
caaggcctcacgcgcatgcctggcggccgcgacgcactcaaaagcagcgtggacgcggtc
aagtactttgggaagggcacctacaccgactgcgctatcaagaaggggctggagcagctc
ctcgtggggggctcccacctgaaggagaataagtacctgattgtggtgaccgacgggcac
cccctggagggctacaaggaaccctgtggggggctggaggatgctgtgaacgaggccaag
cacctgggcgtcaaagtcttctcggtggccatcacacccgaccacctggagccgcgtctg
agcatcatcgccacggaccacacgtaccggcgcaacttcacggcggctgactggggccag
agccgcgacgcagaggaggccatcagccagaccatcgacaccatcgtggacatgatcaaa
aataacgtggagcaagtgtgctgctccttcgaatgccagcctgcaagaggacctccgggg
ctccggggcgaccccggctttgagggagaacgaggcaagccggggctcccaggagagaag
ggagaagccggagatcctggaagacccggggacctcggacctgttgggtaccagggaatg
aagggagaaaaagggagccgtggggagaagggctccaggggacccaagggctacaaggga
gagaagggcaagcgtggcatcgacggggtggacggcgtgaagggggagatggggtaccca
ggcctgccaggctgcaagggctcgcccgggtttgacggcattcaaggaccccctggcccc
aagggagaccccggtgcctttggactgaaaggagaaaagggcgagcctggagctgacggg
gaggcggggagaccagggagctcgggaccatctggagacgagggccagccgggagagcct
gggccccccggagagaaaggagaggcgggcgacgaggggaacccaggacctgacggtgcc
cccggggagcggggtggccctggagagagaggaccacgggggaccccaggcacgcgggga
ccaagaggagaccctggtgaagctggcccgcagggtgatcagggaagagaaggccccgtt
ggtgtccctggagacccgggcgaggctggccctatcggacctaaaggctaccgaggcgat
gagggtcccccagggtccgagggtgccagaggagccccaggacctgccggaccccctgga
gacccggggctgatgggtgaaaggggagaagacggccccgctggaaatggcaccgagggc
ttccccggcttccccgggtatccgggcaacaggggcgctcccgggataaacggcacgaag
ggctaccccggcctcaagggggacgagggagaagccggggaccccggagacgataacaac
gacattgcaccccgaggagtcaaaggagcaaaggggtaccggggtcccgagggcccccag
ggacccccaggacaccaaggaccgcctgggccggacgaatgcgagattttggacatcatc
atgaaaatgtgctcttgctgtgaatgcaagtgcggccccatcgacctcctgttcgtgctg
gacagctcagagagcattggcctgcagaacttcgagattgccaaggacttcgtcgtcaag
gtcatcgaccggctgagccgggacgagctggtcaagttcgagccagggcagtcgtacgcg
ggtgtggtgcagtacagccacagccagatgcaggagcacgtgagcctgcgcagccccagc
atccggaacgtgcaggagctcaaggaagccatcaagagcctgcagtggatggcgggcggc
accttcacgggggaggccctgcagtacacgcgggaccagctgctgccgcccagcccgaac
aaccgcatcgccctggtcatcactgacgggcgctcagacactcagagggacaccacaccg
ctcaacgtgctctgcagccccggcatccaggtggtctccgtgggcatcaaagacgtgttt
gacttcatcccaggctcagaccagctcaatgtcatttcttgccaaggcctggcaccatcc
cagggccggcccggcctctcgctggtcaaggagaactatgcagagctgctggaggatgcc
ttcctgaagaatgtcaccgcccagatctgcatagacaagaagtgtccagattacacctgc
cccatcacgttctcctccccggctgacatcaccatcctgctggacggctccgccagcgtg
ggcagccacaactttgacaccaccaagcgcttcgccaagcgcctggccgagcgcttcctc
acagcgggcaggacggaccccgcccacgacgtgcgggtggcggtggtgcagtacagcggc
acgggccagcagcgcccagagcgggcgtcgctgcagttcctgcagaactacacggccctg
gccagtgccgtcgatgccatggactttatcaacgacgccaccgacgtcaacgatgccctg
ggctatgtgacccgcttctaccgcgaggcctcgtccggcgctgccaagaagaggctgctg
ctcttctcagatggcaactcgcagggcgccacgcccgctgccatcgagaaggccgtgcag
gaagcccagcgggcaggcatcgagatcttcgtggtggtcgtgggccgccaggtgaatgag
ccccacatccgcgtcctggtcaccggcaagacggccgagtacgacgtggcctacggcgag
agccacctgttccgtgtccccagctaccaggccctgctccgcggtgtcttccaccagaca
gtctccaggaaggtggcgctgggctag

KEGG   Homo sapiens (human): 1292Help
Entry
1292              CDS       T01001                                 

Gene name
COL6A2, BTHLM1, PP3610, UCMD1
Definition
(RefSeq) collagen type VI alpha 2 chain
  KO
K06238  collagen, type VI, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04974  Protein digestion and absorption
hsa05165  Human papillomavirus infection
Disease
H01338  Myosclerosis
H01340  Bethlem myopathy
H01341  Collagen VI myopathy
H01778  Ullrich disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1292 (COL6A2)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1292 (COL6A2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1292 (COL6A2)
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    1292 (COL6A2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1292 (COL6A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1292 (COL6A2)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1292 (COL6A2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   1292 (COL6A2)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1292 (COL6A2)
 Hyaluronan
  Extracellular matrix or blood plasma proteins
   1292 (COL6A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: VWA Collagen VWA_2 VWA_3 Ins134_P3_kin_N ParE-like_toxin
Motif
Other DBs
NCBI-GeneID: 1292
NCBI-ProteinID: NP_001840
OMIM: 120240
HGNC: 2212
Ensembl: ENSG00000142173
Vega: OTTHUMG00000090489
Pharos: P12110(Tbio)
UniProt: P12110 A0A384MDP3
LinkDB All DBs
Position
21q22.3
AA seq 1019 aa AA seqDB search
MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQ
SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIK
NLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERA
REEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKH
EAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK
GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA
GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK
GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL
GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG
DFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRE
TCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRV
GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRR
QKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKP
QQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDG
SERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTA
IHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHES
AHSMRKQNVVPTVLALGSDVDMDVLTTLSLGDRAAVFHEKDYDSLAQPGFFDRFIRWIC
NT seq 3060 nt NT seq  +upstreamnt  +downstreamnt
atgctccagggcacctgctccgtgctcctgctctggggaatcctgggggccatccaggcc
cagcagcaggaggtcatctcgccggacactaccgagagaaacaacaactgcccagagaag
accgactgccccatccacgtgtacttcgtgctggacacctcggagagcgtcaccatgcag
tcccccacggacatcctgctcttccacatgaagcagttcgtgccgcagttcatcagccag
ctgcagaacgagttctacctggaccaggtggcgctgagctggcgctacggcggcctgcac
ttctctgaccaggtggaggtgttcagcccaccgggcagcgaccgggcctccttcatcaag
aacctgcagggcatcagctccttccgccgcggcaccttcaccgactgcgcgctggccaac
atgacggagcagatccggcaggaccgcagcaagggcaccgtccacttcgccgtggtcatc
accgacggccacgtcaccggcagcccctgcgggggcatcaagctgcaggccgagcgggcc
cgcgaggagggcatccggctcttcgccgtggcccccaaccagaacctgaaggagcagggc
ctgcgggacatcgccagcacgccgcacgagctctaccgcaacgactacgccaccatgctg
cccgactccaccgagatcgaccaggacaccatcaaccgcatcatcaaggtcatgaaacac
gaagcctacggagagtgctacaaggtgagctgcctggaaatccctgggccctctggcccc
aagggctaccgtggacagaagggtgccaagggcaacatgggtgagccgggagagcctggc
cagaagggaagacagggagacccgggcatcgaaggccccattggattcccaggacccaag
ggcgttcctggcttcaaaggagagaagggtgaatttggagccgacggtcgcaagggggcc
cctggcctggctggcaagaacgggaccgatggacagaagggcaagctggggcgcatcgga
cctcctggctgcaagggagaccctggaaaccggggccccgacggttacccgggggaagca
gggagtccaggggagcgaggagaccaaggcggcaagggggaccctggccgcccaggacgc
agagggcccccgggagaaatcggggccaagggaagcaaggggtatcaaggcaacagtgga
gccccaggaagtcctggtgtgaaaggagccaagggcgggcctgggccccgcggacccaaa
ggcgagccggggcgcaggggagaccccggcaccaagggcagcccaggcagcgatggcccc
aagggggagaagggggaccctggccctgaggggccccgcggcctggctggagaggttggc
aacaaaggagccaagggagaccgaggcttgcctggacccagaggcccccagggagctctt
ggggagcccggaaagcagggatctcggggagaccccggtgatgcaggaccccgtggagac
tcaggacagccaggccccaagggagaccccggcaggcctggattcagctacccaggaccc
cgaggagcacccggagaaaaaggcgagcccggcccacgcggccccgagggaggccgaggc
gactttggcttgaaaggagaacctgggaggaaaggagagaaaggagagcctgcggatcct
ggtccccctggtgagccaggccctcgggggccaagaggagtcccaggacccgagggtgag
cccggcccccctggagaccccggtctcacggagtgtgacgtcatgacctacgtgagggag
acctgcgggtgctgcgactgtgagaagcgctgtggcgccctggacgtggtcttcgtcatc
gacagctccgagagcattgggtacaccaacttcacactggagaagaacttcgtcatcaac
gtggtcaacaggctgggtgccatcgctaaggaccccaagtccgagacagggacgcgtgtg
ggcgtggtgcagtacagccacgagggcacctttgaggccatccagctggacgacgaacgt
atcgactccctgtcgagcttcaaggaggctgtcaagaacctcgagtggattgcgggcggc
acctggacaccctcagccctcaagtttgcctacgaccgcctcatcaaggagagccggcgc
cagaagacacgtgtgtttgcggtggtcatcacggacgggcgccacgaccctcgggacgat
gacctcaacttgcgggcgctgtgcgaccgcgacgtcacagtgacggccatcggcatcggg
gacatgttccacgagaagcacgagagtgaaaacctctactccatcgcctgcgacaagcca
cagcaggtgcgcaacatgacgctgttctccgacctggtcgctgagaagttcatcgatgac
atggaggacgtcctctgcccggaccctcagatcgtgtgcccagaccttccctgccaaaca
gagctgtccgtggcacagtgcacgcagcggcccgtggacatcgtcttcctgctggacggc
tccgagcggctgggtgagcagaacttccacaaggcccggcgcttcgtggagcaggtggcg
cggcggctgacgctggcccggagggacgacgaccctctcaacgcacgcgtggcgctgctg
cagtttggtggccccggcgagcagcaggtggccttcccgctgagccacaacctcacggcc
atccacgaggcgctggagaccacacaatacctgaactccttctcgcacgtgggcgcaggc
gtggtgcacgccatcaatgccatcgtgcgcagcccgcgtggcggggcccggaggcacgca
gagctgtccttcgtgttcctcacggacggcgtcacgggcaacgacagtctgcacgagtcg
gcgcactccatgcgcaagcagaacgtggtacccaccgtgctggccttgggcagcgacgtg
gacatggacgtgctcaccacgctcagcctgggtgaccgcgccgccgtgttccacgagaag
gactatgacagcctggcgcaacccggcttcttcgaccgcttcatccgctggatctgctag

KEGG   Homo sapiens (human): 1293Help
Entry
1293              CDS       T01001                                 

Gene name
COL6A3, BTHLM1, DYT27, UCMD1
Definition
(RefSeq) collagen type VI alpha 3 chain
  KO
K06238  collagen, type VI, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04974  Protein digestion and absorption
hsa05165  Human papillomavirus infection
Disease
H00831  Primary dystonia
H01340  Bethlem myopathy
H01341  Collagen VI myopathy
H01778  Ullrich disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1293 (COL6A3)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1293 (COL6A3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1293 (COL6A3)
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    1293 (COL6A3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1293 (COL6A3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1293 (COL6A3)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1293 (COL6A3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   1293 (COL6A3)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1293 (COL6A3)
 Hyaluronan
  Extracellular matrix or blood plasma proteins
   1293 (COL6A3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: VWA VWA_2 Collagen VWA_3 Kunitz_BPTI
Motif
Other DBs
NCBI-GeneID: 1293
NCBI-ProteinID: NP_004360
OMIM: 120250
HGNC: 2213
Ensembl: ENSG00000163359
Vega: OTTHUMG00000150020
Pharos: P12111(Tbio)
UniProt: P12111 D9ZGF2 Q8N4Z1 Q63HQ4
LinkDB All DBs
Structure
PDB: 

Position
2q37.3
AA seq 3177 aa AA seqDB search
MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE
FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK
GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA
DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS
ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS
TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD
EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV
GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD
LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS
AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS
LVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD
FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTG
SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ
ANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILF
LFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL
NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPA
SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA
PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF
YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT
ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV
ISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVD
YLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVS
RNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVK
ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL
IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL
DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA
QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATP
APPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGL
VQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLD
QRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVG
NVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFES
KVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQ
HPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILV
GLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQR
GDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFP
GEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP
GQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGF
EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP
KGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR
GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFP
TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF
ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT
RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN
VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK
YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD
FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL
QAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFV
SSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTT
KPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPAT
AAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEI
TENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVC
YLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGT
CRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT
NT seq 9534 nt NT seq  +upstreamnt  +downstreamnt
atgaggaaacatcggcacttgcccttagtggccgtcttttgcctctttctctcaggcttt
cctacaactcatgcccagcagcagcaagcagatgtcaaaaatggtgcggctgctgatata
atatttctagtggattcctcttggaccattggagaggaacatttccaacttgttcgagag
tttctatatgatgttgtaaaatccttagctgtgggagaaaatgatttccattttgctctg
gtccagttcaacggaaacccacataccgagttcctgttaaatacgtatcgtactaaacaa
gaagtcctttctcatatttccaacatgtcttatattgggggaaccaatcagactggaaaa
ggattagaatacataatgcaaagccacctcaccaaggctgctggaagccgggccggtgac
ggagtccctcaggttatcgtagtgttaactgatggacactcgaaggatggccttgctctg
ccctcagcggaacttaagtctgctgatgttaacgtgtttgcaattggagttgaggatgca
gatgaaggagcgttaaaagaaatagcaagtgaaccgctcaatatgcatatgttcaaccta
gagaattttacctcacttcatgacatagtaggaaacttagtgtcctgtgtgcattcatcc
gtgagtccagaaagggctggggacacggaaacccttaaagacatcacagcacaagactct
gctgacattattttccttattgatggatcaaacaacaccggaagtgtcaatttcgcagtc
attctcgacttccttgtaaatctccttgagaaactcccaattggaactcagcagatccga
gtgggggtggtccagtttagcgatgagcccagaaccatgttctccttggacacctactcc
accaaggcccaggttctgggtgcagtgaaagccctcgggtttgctggtggggagttggcc
aatatcggcctcgcccttgatttcgtggtggagaaccacttcacccgggcagggggcagc
cgcgtggaggaaggggttccccaggtgctggtcctcataagtgccgggccttctagtgac
gagattcgctacggggtggtagcactgaagcaggctagcgtgttctcattcggccttgga
gcccaggccgcctccagggcagagcttcagcacatagctaccgatgacaacttggtgttt
actgtcccggaattccgtagctttggggacctccaggagaaattactgccgtacattgtt
ggcgtggcccaaaggcacattgtcttgaaaccgccaaccattgtcacacaagtcattgaa
gtcaacaagagagacatagtcttcctggtggatggctcatctgcactgggactggccaac
ttcaatgccatccgagacttcattgctaaagtcatccagaggctggaaatcggacaggat
cttatccaggtggcagtggcccagtatgcagacactgtgaggcctgaattttatttcaat
acccatccaacaaaaagggaagtcataaccgctgtgcggaaaatgaagcccctggacggc
tcggccctgtacacgggctctgctctagactttgttcgtaacaacctattcacgagttca
gccggctaccgggctgccgaggggattcctaagcttttggtgctgatcacaggtggtaag
tccctagatgaaatcagccagcctgcccaggagctgaagagaagcagcataatggccttt
gccattgggaacaagggtgccgatcaggctgagctggaagagatcgctttcgactcctcc
ctggtgttcatcccagctgagttccgagccgccccattgcaaggcatgctgcctggcttg
ctggcacctctcaggaccctctctggaacccctgaagttcactcaaacaaaagggatatc
atctttcttttggatggatcagccaacgttggaaaaaccaatttcccttatgtgcgcgac
tttgtaatgaacctagttaacagccttgatattggaaatgacaatattcgtgttggttta
gtgcaatttagtgacactcctgtaacggagttctctttaaacacataccagaccaagtca
gatatccttggtcatctgaggcagctgcagctccagggaggttcgggcctgaacacaggc
tcagccctaagctatgtctatgccaaccacttcacggaagctggcggcagcaggatccgt
gaacacgtgccgcagctcctgcttctgctcacagctgggcagtctgaggactcctatttg
caagctgccaacgccttgacacgcgcgggcatcctgactttttgtgtgggagctagccag
gcgaataaggcagagcttgagcagattgcttttaacccaagcctggtgtatctcatggat
gatttcagctccctgccagctttgcctcagcagctgattcagcccctaaccacatatgtt
agtggaggtgtggaggaagtaccactcgctcagccagagagcaagcgagacattctgttc
ctctttgacggctcagccaatcttgtgggccagttccctgttgtccgtgactttctctac
aagattatcgatgagctcaatgtgaagccagaggggacccgaattgcggtggctcagtac
agcgatgatgtcaaggtggagtcccgttttgatgagcaccagagtaagcctgagatcctg
aatcttgtgaagagaatgaagatcaagacgggcaaagccctcaacctgggctacgcgctg
gactatgcacagaggtacatttttgtgaagtctgctggcagccggatcgaggatggagtg
cttcagttcctggtgctgctggtcgcaggaaggtcatctgaccgtgtggatgggccagca
agtaacctgaagcagagtggggttgtgcctttcatcttccaagccaagaacgcagaccct
gctgagttagagcagatcgtgctgtctccagcgtttatcctggctgcagagtcgcttccc
aagattggagatcttcatccacagatagtgaatctcttaaaatcagtgcacaacggagca
ccagcaccagtttcaggtgaaaaggacgtggtgtttctgcttgatggctctgagggcgtc
aggagcggcttccctctgttgaaagagtttgtccagagagtggtggaaagcctggatgtg
ggccaggaccgggtccgcgtggccgtggtgcagtacagcgaccggaccaggcccgagttc
tacctgaattcatacatgaacaagcaggacgtcgtcaacgctgtccgccagctgaccctg
ctgggagggccgacccccaacaccggggccgccctggagtttgtcctgaggaacatcctg
gtcagctctgcgggaagcaggataacagaaggtgtgccccagctgctgatcgtcctcacg
gccgacaggtctggggatgatgtgcggaacccctccgtggtcgtgaagaggggtggggct
gtgcccattggcattggcatcgggaacgctgacatcacagagatgcagaccatctccttc
atcccggactttgccgtggccattcccacctttcgccagctggggaccgtccaacaggtc
atctctgagagggtgacccagctcacccgcgaggagctgagcaggctgcagccggtgttg
cagcctctaccgagcccaggtgttggtggcaagagggacgtggtctttctcatcgatggg
tcccaaagtgccgggcctgagttccagtacgttcgcaccctcatagagaggctggttgac
tacctggacgtgggctttgacaccacccgggtggctgtcatccagttcagcgatgacccc
aaggtggagttcctgctgaacgcccattccagcaaggatgaagtgcagaacgcggtgcag
cggctgaggcccaagggagggcggcagatcaacgtgggcaatgccctggagtacgtgtcc
aggaacatcttcaagaggcccctggggagccgcattgaagagggcgtcccgcagttcctg
gtcctcatctcgtctggaaagtctgacgatgaggtggacgacccggcggtggagctcaag
cagtttggcgtggcccctttcacgatcgccaggaacgcagaccaggaggagctggtgaag
atctcgctgagccccgaatatgtgttctcggtgagcaccttccgggagctgcccagcctg
gagcagaaactgctgacgcccatcacgaccctgacctcagagcagatccagaagctctta
gccagcactcgctatccacctccagcagttgagagtgatgctgcagacattgtctttctg
atcgacagctctgagggagttaggccagatggctttgcacatattcgagattttgttagc
aggattgttcgaagactcaacatcggccccagtaaagtgagagttggggtcgtgcagttc
agcaatgatgtcttcccagaattctatctgaaaacctacagatcccaggccccggtgctg
gacgccatacggcgcctgaggctcagaggggggtccccactgaacactggcaaggctctc
gaatttgtggcaagaaacctctttgttaagtctgcggggagtcgcatagaagacggggtg
ccccaacacctggtcctggtcctgggtggaaaatcccaggacgatgtgtccaggttcgcc
caggtgatccgttcctcgggcattgtgagtttaggggtaggagaccggaacatcgacaga
acagagctgcagaccatcaccaatgaccccagactggtcttcacagtgcgagagttcaga
gagcttcccaacatagaagaaagaatcatgaactcgtttggaccctccgcagccactcct
gcacctccaggggtggacacccctcctccttcacggccagagaagaagaaagcagacatt
gtgttcctgttggatggttccatcaacttcaggagggacagtttccaggaagtgcttcgt
tttgtgtctgaaatagtggacacagtttatgaagatggcgactccatccaagtggggctt
gtccagtacaactctgaccccactgacgaattcttcctgaaggacttctctaccaagagg
cagattattgacgccatcaacaaagtggtctacaaagggggaagacacgccaacactaag
gtgggccttgagcacctgcgggtaaaccactttgtgcctgaggcaggcagccgcctggac
cagcgggtccctcagattgcctttgtgatcacgggaggaaagtcggtggaagatgcacag
gatgtgagcctggccctcacccagaggggggtcaaagtgtttgctgttggagtgaggaat
atcgactcggaggaggttggaaagatagcgtccaacagcgccacagcgttccgcgtgggc
aacgtccaggagctgtccgaactgagcgagcaagttttggaaactttgcatgatgcgatg
catgaaaccctttgccctggtgtaactgatgctgccaaagcttgtaatctggatgtgatt
ctggggtttgatggttctagagaccagaatgtttttgtggcccagaagggcttcgagtcc
aaggtggacgccatcttgaacagaatcagccagatgcacagggtcagctgcagcggtggc
cgctcgcccaccgtgcgtgtgtcagtggtggccaacacgccctcgggcccggtggaggcc
tttgactttgacgagtaccagccagagatgctcgagaagttccggaacatgcgcagccag
cacccctacgtcctcacggaggacaccctgaaggtctacctgaacaagttcagacagtcc
tcgccggacagcgtgaaggtggtcattcattttactgatggagcagacggagatctggct
gatttacacagagcatctgagaacctccgccaagaaggagtccgtgccttgatcctggtg
ggccttgaacgagtggtcaacttggagcggctaatgcatctggagtttgggcgagggttt
atgtatgacaggcccctgaggcttaacttgctggacttggattatgaactagcggagcag
cttgacaacattgccgagaaagcttgctgtggggttccctgcaagtgctctgggcagagg
ggagaccgcgggcccatcggcagcatcgggccaaagggtattcctggagaagacggctac
cgaggctatcctggtgatgagggtggacccggtgagcgtggtccgcctggtgtgaacggc
actcaaggtttccagggctgcccgggccagagaggagtaaagggctctcggggattccca
ggagagaagggcgaagtaggagaaattggactggatggtctggatggtgaagatggagac
aaaggattgcctggttcttctggagagaaagggaatcctggaagaaggggtgataaagga
cctcgaggagagaaaggagaaagaggagatgttgggattcgaggggacccgggtaaccca
ggacaagacagccaggagagaggacccaaaggagaaaccggtgacctcggccccatgggt
gtcccagggagagatggagtacctggaggacctggagaaactgggaagaatggtggcttt
ggccgaaggggaccccccggagctaagggcaacaagggcggtcctggccagccgggcttt
gagggagagcaggggaccagaggtgcacagggcccagctggtcctgctggtcctccaggg
ctgataggagaacaaggcatttctggacctcggggaagcggaggtgccgctggtgctcct
ggagaacgaggcagaaccggtccactgggaagaaagggtgagcccggagagccaggacca
aaaggaggaatcgggaaccggggccctcgtggggagacgggagatgacgggagagacgga
gttggcagtgaaggacgcagaggcaaaaaaggagaaagaggattccctggatacccagga
ccaaagggtaacccaggtgaacctgggctaaatggaacaacaggacccaaaggcatcaga
ggccgaaggggaaattcgggacctccagggatagttggacagaagggagaccctggctac
ccaggaccagctggtcccaagggcaacaggggcgactccatcgatcaatgtgccctcatc
caaagcatcaaagataaatgcccttgctgttacgggcccctggagtgccccgtcttccca
acagaactagcctttgctttagacacctctgagggagtcaaccaagacactttcggccgg
atgcgagatgtggtcttgagtattgtgaatgacctgaccattgctgagagcaactgccca
cggggggcccgggtggctgtggtcacctacaacaacgaggtgaccacggagatccggttt
gctgactccaagaggaagtcggtcctcctggacaagattaagaaccttcaggtggctctg
acatccaaacagcagagtctggagactgccatgtcgtttgtggccaggaacacatttaag
cgtgtgaggaacggattcctaatgaggaaagtggctgttttcttcagcaacacacccaca
agagcatccccacagctcagagaggctgtgctcaagctctcagatgcggggatcaccccc
ttgttccttacaaggcaggaagaccggcagctcatcaacgctttgcagatcaataacaca
gcagtggggcatgcgcttgtcctgcctgcagggagagacctcacagacttcctggagaat
gtcctcacgtgtcatgtttgcttggacatctgcaacatcgacccatcctgtggatttggc
agttggaggccttccttcagggacaggagagcggcagggagcgatgtggacatcgacatg
gctttcatcttagacagcgctgagaccaccaccctgttccagttcaatgagatgaagaag
tacatagcgtacctggtcagacaactggacatgagcccagatcccaaggcctcccagcac
ttcgccagagtggcagttgtgcagcacgcgccctctgagtccgtggacaatgccagcatg
ccacctgtgaaggtggaattctccctgactgactatggctccaaggagaagctggtggac
ttcctcagcaggggaatgacacagttgcagggaaccagggccttaggcagtgccattgaa
tacaccatagagaatgtctttgaaagtgccccaaacccacgggacctgaaaattgtggtc
ctgatgctgacgggcgaggtgccggagcagcagctggaggaggcccagagagtcatcctg
caggccaaatgcaagggctacttcttcgtggtcctgggcattggcaggaaggtgaacatc
aaggaggtatacaccttcgccagtgagccaaacgacgtcttcttcaaattagtggacaag
tccaccgagctcaacgaggagcctttgatgcgcttcgggaggctgttgccatccttcgtc
agcagtgaaaatgctttttacttgtccccagatatcaggaaacagtgtgattggttccaa
ggggaccaacccacaaagaaccttgtgaagtttggtcacaaacaagtaaatgttccgaat
aacgttacttcaagtcctacatccaacccagtgacgacaacgaagccggtgactacgacg
aagccggtgaccaccacaacaaagcctgtaaccaccacaacaaagcctgtgactattata
aatcagccatctgtgaagccagccgctgcaaagccggcccctgcgaaacctgtggctgcc
aagcctgtggccacaaagatggccactgttagacccccagtggcggtgaagccagcaacg
gcagcgaagcctgtagcagcaaagccagcagctgtaagaccccccgctgctgctgctgca
aaaccagtggcgaccaagcctgaggtccctaggccacaggcagccaaaccagctgccacc
aagccagccaccactaagcccatggttaagatgtcccgtgaagtccaggtgtttgagata
acagagaacagcgccaaactccactgggagagggctgagccccccggtccttatttttat
gacctcaccgtcacctcagcccatgatcagtccctggttctgaagcagaacctcacggtc
acggaccgcgtcattggaggcctgctcgctgggcagacataccatgtggctgtggtctgc
tacctgaggtctcaggtcagagccacctaccacggaagtttcagtacaaagaaatctcag
cccccacctccacagccagcaaggtcagcttctagttcaaccatcaatctaatggtgagc
acagaaccattggctctcactgaaacagatatatgcaagttgccgaaagacgaaggaact
tgcagggatttcatattaaaatggtactatgatccaaacaccaaaagctgtgcaagattc
tggtatggaggttgtggtggaaacgaaaacaaatttggatcacagaaagaatgtgaaaag
gtttgcgctcctgtgctcgccaaacccggagtcatcagtgtgatgggaacctaa

KEGG   Homo sapiens (human): 1297Help
Entry
1297              CDS       T01001                                 

Gene name
COL9A1, DJ149L1.1.2, EDM6, MED, STL4
Definition
(RefSeq) collagen type IX alpha 1 chain
  KO
K08131  collagen, type IX, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04974  Protein digestion and absorption
hsa05165  Human papillomavirus infection
Disease
H00476  Multiple epiphyseal dysplasia
H02072  Stickler syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1297 (COL9A1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1297 (COL9A1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1297 (COL9A1)
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    1297 (COL9A1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1297 (COL9A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00535 Proteoglycans [BR:hsa00535]
    1297 (COL9A1)
Proteoglycans [BR:hsa00535]
 Extracellular matrix (ECM) proteoglycans
  Collagen family
   1297 (COL9A1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Collagen Laminin_G_2 Laminin_G_3 Toxin_R_bind_N
Motif
Other DBs
NCBI-GeneID: 1297
NCBI-ProteinID: NP_001842
OMIM: 120210
HGNC: 2217
Ensembl: ENSG00000112280
Vega: OTTHUMG00000014988
Pharos: P20849(Tbio)
UniProt: P20849
LinkDB All DBs
Structure
PDB: 

Position
6q13
AA seq 921 aa AA seqDB search
MKTCWKIPVFFFVCSFLEPWASAAVKRRPRFPVNSNSNGGNELCPKIRIGQDDLPGFDLI
SQFQVDKAASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMT
GSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQW
HKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAVLGKLADNPQVSVPFELQWMLI
HCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP
PGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIP
GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRS
GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDK
GEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP
GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM
GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP
GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR
GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS
LKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEK
GERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGF
CEPASCTMQAGQRAFNKGPDP
NT seq 2766 nt NT seq  +upstreamnt  +downstreamnt
atgaagacctgctggaaaattccagttttcttctttgtgtgcagtttcctggaaccctgg
gcatctgcagctgtcaagcgtcgccccagattccctgtcaattccaattctaatggtgga
aatgaactctgtccaaagatcaggattggccaagatgacttaccagggtttgatctgatc
tctcagttccaggtagataaagcagcatctagaagagctatccagagagtagtgggatca
gctacattgcaggtggcttacaagttgggaaataatgtagacttcaggattccaactagg
aatttatatcccagtggactgcctgaagaatactccttcttgacgacgtttcgaatgact
ggaagcactctcaaaaagaactggaacatttggcagattcaggattcctctgggaaggag
caagttggcataaagattaatggccaaacacaatctgttgtattttcatacaagggactg
gatggaagtctccaaacagcagccttttcgaatttgtcctccttgtttgattcccagtgg
cataagatcatgattggcgtggagaggagtagtgctactctttttgttgactgcaacagg
attgaatctttacctataaagccaagaggcccaattgacattgatggctttgctgtgctg
ggaaaacttgcagataatcctcaagtttctgttccatttgaacttcaatggatgctgatc
cattgtgaccccctgcggcccaggagagaaacttgccatgagctgccagccagaataacg
cccagccagaccaccgacgagagaggtcccccgggtgagcagggtcctcccgggcctccg
ggcccccctggagttccaggcatcgatggcatcgacggtgaccgaggtcctaagggcccc
ccgggccccccgggtcctgcaggtgaaccgggaaagccaggagctccaggcaagcctggc
acacctggcgctgatggattaacaggacctgatggatcccctggctccattgggtcaaag
ggacaaaaaggagaacctggtgtgcctggatcgcgtggatttccaggccgtggtattcct
ggaccccctggtcctcctgggacagcaggactccctggagagcttggccgtgtaggacct
gttggtgaccctgggagaagaggaccacctggcccccctggccccccaggacccagagga
acaattggctttcatgatggagatccattgtgtcccaatgcctgtccaccaggtcgctca
ggatatccaggcctaccaggcatgaggggtcataaaggggctaaaggagaaattggtgaa
ccaggaagacaaggacacaagggtgaagaaggtgaccagggagaactcggagaagttgga
gctcaaggacctccaggagcccagggtttgcgaggcatcaccggcatagttggggacaaa
ggggaaaaaggtgctcggggcttagatggtgaacctgggcctcagggtcttcctggtgca
cctggtgatcaaggacagcgaggacctccaggagaagcaggtcccaaaggagatagaggg
gctgaaggtgctagaggaattcctggtctccctgggcccaaaggagacacgggtttgcca
ggtgtggatggccgtgatgggatccctggaatgcctggaacaaagggtgaaccaggaaaa
cctgggcctcctggtgatgcaggattgcaggggttaccaggtgtacctggaattcctggt
gcaaagggtgttgctggtgaaaagggtagcacaggtgctccagggaagcctggtcagatg
ggaaattcaggcaaaccgggccaacaggggcctccaggagaggtgggaccccgaggaccc
caggggcttcctggcagtagaggagaattaggaccagtgggatccccaggcctaccaggt
aaactgggttctctgggtagccctggcctccctggcttgcctgggccccctggacttcct
ggaatgaaaggtgacaggggtgtagtcggtgaaccgggtccaaagggtgaacagggtgcc
tctggtgaagaaggtgaagcaggagaaaggggggaacttggagatataggattacctggc
ccaaagggatctgcaggtaatcctggggaacctggcttgagagggcctgagggaagtcgg
gggcttcctggagtggaaggaccaagaggaccacctggaccccggggtgtgcagggagaa
cagggtgccaccggcctgcctggtgtccagggccctccgggtagagcaccgacagatcag
cacattaagcaggtttgcatgagagtcatacaagaacattttgctgagatggctgccagt
cttaagcgtccagactcaggtgccactgggcttcctggaaggcctggccctcctggtccc
cccggccctcctggagagaatggtttcccaggccagatgggaattcgtggccttccgggc
attaaggggccccctggtgctcttggtttgaggggacctaaaggtgacttgggagaaaag
ggggagcgtggccctccaggaagaggtcccaacggtttgcctggagctataggtctccca
ggtgacccaggccctgccagctatggcagaaatggccgagacggtgagcgaggcccccca
ggggtggcaggaattcctggagtgcctggacccccgggacctcctgggcttcccggtttc
tgtgagccagcctcctgcaccatgcaggctggtcagcgagcatttaacaaagggcctgac
ccttga

KEGG   Homo sapiens (human): 1298Help
Entry
1298              CDS       T01001                                 

Gene name
COL9A2, DJ39G22.4, EDM2, MED, STL5
Definition
(RefSeq) collagen type IX alpha 2 chain
  KO
K08131  collagen, type IX, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04974  Protein digestion and absorption
hsa05165  Human papillomavirus infection
Disease
H00476  Multiple epiphyseal dysplasia
H02072  Stickler syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1298 (COL9A2)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1298 (COL9A2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1298 (COL9A2)
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    1298 (COL9A2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1298 (COL9A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00535 Proteoglycans [BR:hsa00535]
    1298 (COL9A2)
Proteoglycans [BR:hsa00535]
 Extracellular matrix (ECM) proteoglycans
  Collagen family
   1298 (COL9A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Collagen
Motif
Other DBs
NCBI-GeneID: 1298
NCBI-ProteinID: NP_001843
OMIM: 120260
HGNC: 2218
Ensembl: ENSG00000049089
Vega: OTTHUMG00000005761
Pharos: Q14055(Tbio)
UniProt: Q14055
LinkDB All DBs
Position
1p34.2
AA seq 689 aa AA seqDB search
MAAATASPRSLLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAG
PPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGP
PGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPP
GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMA
GPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGAT
GPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLP
GFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQ
GLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPS
GDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEV
AVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKR
GEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGL
PGFCEPAACLGASAYASARLTEPGSIKGP
NT seq 2070 nt NT seq  +upstreamnt  +downstreamnt
atggccgccgctacggcctccccccgcagcctccttgttctcctccaggtggtagtgctc
gctctggcgcagattagaggtccaccgggagagcggggccccccgggtcccccgggaccg
ccgggagtgcctggatccgacggcatcgacggtgacaatgggccccctggaaaagctggc
cctccgggacccaagggcgagcctggcaaagctgggccagatgggccagacgggaagccc
gggattgatggtttaactggagccaagggggagcctggccccatggggatccctggagtc
aagggccagcccgggcttcctggtcctcctggccttccgggccctggttttgctggacct
cctgggcctcctggacctgttggcctccctggtgagattggaatccgaggccccaagggg
gaccctggaccagatggaccatcggggcccccaggaccccctgggaaacctggtcgcccg
ggaaccatccagggtctggaaggcagtgcggatttcctgtgtccaaccaactgtccaccc
ggaatgaaaggtcccccagggctgcagggagtgaaggggcatgcgggcaaacgcgggatt
ctgggtgatcctggccaccaggggaagccgggtcccaagggagatgtgggtgcctctgga
gagcaaggcatccctggaccaccgggtccccagggcatcaggggctacccaggcatggca
gggcccaagggagagacgggccctcatggatataaaggcatggtgggcgctatcggtgcc
actgggccaccgggtgaggaaggtcctaggggaccgccaggccgagctggggagaagggt
gacgagggcagcccaggtattcgtggaccccaggggatcacaggcccgaaaggagcaacg
ggccccccaggcatcaacggcaaggatgggaccccaggcacgcctggcatgaagggcagt
gcaggacaggcgggacagcccggaagtccaggccaccagggcctagcgggtgtgccaggc
cagcctgggacaaaaggaggccctggagaccagggtgagccgggcccgcagggccttcct
ggattctctggtccccctgggaaagagggagagccagggcctcgaggagaaattggtccc
cagggcatcatgggacagaagggtgaccaaggcgagaggggtccagtggggcaaccaggc
cctcagggaaggcagggccctaagggggagcagggcccccccggaattccagggccccaa
ggcttgccaggcgtcaaaggagacaagggctccccagggaagaccgggccccgcggcaaa
gtgggtgacccaggggtggccggcctccccggagagaaaggcgagaagggcgagtccggc
gagccggggcccaagggacagcaaggagtacgtggagaacccggctaccctggccccagc
ggggatgcgggcgccccaggggttcagggctaccctggtccccccggccctcgaggactg
gccgggaaccgaggcgtgccaggacagcccgggagacagggcgtggagggccgggatgcc
actgaccagcacatcgtggatgtggcgctgaagatgctgcaagagcaactggcagaggtc
gccgtgagtgccaagcgggaagccctgggtgcggtgggcatgatgggtcctccaggacct
cctgggccccctgggtacccaggcaagcagggcccccatgggcaccctggccctcggggc
gttcctggcatcgtgggagccgtgggtcagatcggcaacacggggcccaagggaaaacgt
ggagagaagggtgatccaggagaagtgggacgggggcaccccgggatgcctgggccccca
gggatcccaggactccctggccggcctggccaggcaatcaacggcaaggatggagatcga
gggtccccaggggctccaggagaggcaggtcgacctggcctgccaggccccgtggggctg
ccgggcttctgtgaacctgccgcctgccttggagcttcggcctatgcctctgcccgcctt
acagagcctggatccatcaaggggccttga

KEGG   Homo sapiens (human): 1299Help
Entry
1299              CDS       T01001                                 

Gene name
COL9A3, DJ885L7.4.1, EDM3, IDD, MED
Definition
(RefSeq) collagen type IX alpha 3 chain
  KO
K08131  collagen, type IX, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04974  Protein digestion and absorption
hsa05165  Human papillomavirus infection
Disease
H00476  Multiple epiphyseal dysplasia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1299 (COL9A3)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1299 (COL9A3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1299 (COL9A3)
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    1299 (COL9A3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1299 (COL9A3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00535 Proteoglycans [BR:hsa00535]
    1299 (COL9A3)
Proteoglycans [BR:hsa00535]
 Extracellular matrix (ECM) proteoglycans
  Collagen family
   1299 (COL9A3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Collagen
Motif
Other DBs
NCBI-GeneID: 1299
NCBI-ProteinID: NP_001844
OMIM: 120270
HGNC: 2219
Ensembl: ENSG00000092758
Vega: OTTHUMG00000032938
Pharos: Q14050(Tbio)
UniProt: Q14050
LinkDB All DBs
Position
20q13.33
AA seq 684 aa AA seqDB search
MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP
PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLP
GPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPP
GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL
GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP
GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEA
GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ
GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ
GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQL
AAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGD
RGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG
ICDTSACQGAVLGGVGEKSGSRSS
NT seq 2055 nt NT seq  +upstreamnt  +downstreamnt
atggccgggccgcgcgcgtgcgccccgctcctgctcctgctcctgctcggggagcttctg
gcggccgccggggcgcagagagtgggactccccggcccccccggccccccagggccgccc
gggaagcccggccaggacggcattgacggagaagctggtcctccaggtctgcctgggccc
ccgggaccaaagggggccccaggaaagccggggaaaccaggagaggctgggctgccggga
ctgccgggtgtggatggtctgactggacgagatggaccccctggacccaagggtgcccct
ggggaacggggaagtctgggacccccggggccgcccgggctggggggcaaaggcctccct
ggaccccccggagaggcaggagtgagcggccccccaggtgggatcggcctccgcggcccc
ccgggaccttctggactccccggcctccctggtcccccaggacctcccggaccccctgga
cacccaggagtcctccctgaaggcgctactgaccttcagtgcccaagtatctgcccgcca
ggtcccccagggccccctggaatgccagggttcaagggacccactggctacaaaggcgag
cagggggaagtcggcaaggacggcgagaagggtgaccctggcccccctgggcccgccggc
ctcccgggcagcgtggggctgcagggcccccggggattacgaggactgccagggccactc
gggccccctggggaccggggtcccattgggttccgagggccgcctgggatcccaggagcg
cctgggaaagcgggtgaccgaggcgagaggggcccagaagggttccgcggccccaagggt
gacctcggcagacctggtcccaagggaacccccggagtggccgggccaagcggagagccg
ggcatgccgggcaaggacggccagaatggcgtgccaggactcgatggccagaagggagag
gctggtcgcaacggtgctccgggagagaagggccccaacgggctgccgggcctccctgga
cgagcggggtccaaaggcgagaagggagaacggggcagagctggggagctgggtgaggcc
ggcccctctggagagccaggcgtccctggagatgctggcatgcctggggagcgcggtgag
gctggccaccggggctcagcgggggccctcggcccacaaggccctcccggagcccctggt
gtccgaggcttccagggccagaagggcagcatgggagaccccggccttccaggcccccag
ggcctccgaggtgacgtgggcgaccggggtccgggaggtgccgcaggccctaagggagac
cagggtattgcaggttccgacggtcttcctggggataaaggagaactgggtcccagcggc
ctggtcggacccaaaggagagtctggcagtcgaggggagctgggccccaaaggcacccag
ggtcccaacggcaccagcggtgttcagggtgtccccgggccccccggtcctctgggcctg
cagggcgtcccgggtgttcctggcatcacggggaagccgggagttccggggaaggaggcc
agcgagcagcgcatcagggagctgtgtggggggatgatcagcgaacaaattgcacagtta
gccgcgcacctaaggaagcctttggcacccgggtccattggtcggcccggtccagctggc
ccccctgggcccccaggacccccaggctccattggtcaccctggcgctcgaggaccccct
ggataccgcggtcccactggggagctgggagaccccgggcccagaggaaaccagggtgac
agaggagacaaaggcgcggcaggagcagggctggacgggcctgaaggagaccaggggccc
caaggaccccaaggcgtgcccggcaccagcaaggacggccaggacggtgctcccggcgag
cctgggcctcccggagatcctgggcttccaggtgccattggggcccaggggacaccgggg
atctgcgacacctcagcctgccaaggagccgtgttaggaggggtcggggagaaatcaggc
tctcgaagctcataa

KEGG   Homo sapiens (human): 1311Help
Entry
1311              CDS       T01001                                 

Gene name
COMP, EDM1, EPD1, MED, PSACH, THBS5, TSP5
Definition
(RefSeq) cartilage oligomeric matrix protein
  KO
K04659  thrombospondin 2/3/4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05144  Malaria
hsa05165  Human papillomavirus infection
Disease
H00476  Multiple epiphyseal dysplasia
H00477  Pseudoachondroplasia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    1311 (COMP)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    1311 (COMP)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    1311 (COMP)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    1311 (COMP)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1311 (COMP)
  09174 Infectious disease: parasitic
   05144 Malaria
    1311 (COMP)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    1311 (COMP)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1311 (COMP)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1311 (COMP)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Phagocytosis
   Opsonins
    1311 (COMP)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   1311 (COMP)
  Exosomal proteins of colorectal cancer cells
   1311 (COMP)
  Exosomal proteins of bladder cancer cells
   1311 (COMP)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   1311 (COMP)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: TSP_C TSP_3 COMP EGF_CA cEGF EGF_3 EGF_MSP1_1 EGF hEGF
Motif
Other DBs
NCBI-GeneID: 1311
NCBI-ProteinID: NP_000086
OMIM: 600310
HGNC: 2227
Ensembl: ENSG00000105664
Vega: OTTHUMG00000169318
Pharos: P49747(Tbio)
UniProt: P49747
LinkDB All DBs
Structure
PDB: 

Position
19p13.11
AA seq 757 aa AA seqDB search
MVPDTACVLLLTLAALGASGQGQSPLGSDLGPQMLRELQETNAALQDVRELLRQQVREIT
FLKNTVMECDACGMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTG
NGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTD
INECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEH
ADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQ
EDVDRDGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQK
DTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQAD
VDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDS
RDNCRLVPNPGQEDADRDGVGDVCQDDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLD
PEGDAQIDPNWVVLNQGREIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFI
FGYQDSSSFYVVMWKQMEQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDT
ESQVRLLWKDPRNVGWKDKKSYRWFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGG
RLGVFCFSQENIIWANLRYRCNDTIPEDYETHQLRQA
NT seq 2274 nt NT seq  +upstreamnt  +downstreamnt
atggtccccgacaccgcctgcgttcttctgctcaccctggctgccctcggcgcgtccgga
cagggccagagcccgttgggctcagacctgggcccgcagatgcttcgggaactgcaggaa
accaacgcggcgctgcaggacgtgcgggagctgctgcggcagcaggtcagggagatcacg
ttcctgaaaaacacggtgatggagtgtgacgcgtgcgggatgcagcagtcagtacgcacc
ggcctacccagcgtgcggcccctgctccactgcgcgcccggcttctgcttccccggcgtg
gcctgcatccagacggagagcggcgcgcgctgcggcccctgccccgcgggcttcacgggc
aacggctcgcactgcaccgacgtcaacgagtgcaacgcccacccctgcttcccccgagtc
cgctgtatcaacaccagcccggggttccgctgcgaggcttgcccgccggggtacagcggc
cccacccaccagggcgtggggctggctttcgccaaggccaacaagcaggtttgcacggac
atcaacgagtgtgagaccgggcaacataactgcgtccccaactccgtgtgcatcaacacc
cggggctccttccagtgcggcccgtgccagcccggcttcgtgggcgaccaggcgtccggc
tgccagcggcgcgcacagcgcttctgccccgacggctcgcccagcgagtgccacgagcat
gcagactgcgtcctagagcgcgatggctcgcggtcgtgcgtgtgtgccgttggctgggcc
ggcaacgggatcctctgtggtcgcgacactgacctagacggcttcccggacgagaagctg
cgctgcccggagcgccagtgccgtaaggacaactgcgtgactgtgcccaactcagggcag
gaggatgtggaccgcgatggcatcggagacgcctgcgatccggatgccgacggggacggg
gtccccaatgaaaaggacaactgcccgctggtgcggaacccagaccagcgcaacacggac
gaggacaagtggggcgatgcgtgcgacaactgccggtcccagaagaacgacgaccaaaag
gacacagaccaggacggccggggcgatgcgtgcgacgacgacatcgacggcgaccggatc
cgcaaccaggccgacaactgccctagggtacccaactcagaccagaaggacagtgatggc
gatggtataggggatgcctgtgacaactgtccccagaagagcaacccggatcaggcggat
gtggaccacgactttgtgggagatgcttgtgacagcgatcaagaccaggatggagacgga
catcaggactctcgggacaactgtcccacggtgcctaacagtgcccaggaggactcagac
cacgatggccagggtgatgcctgcgacgacgacgacgacaatgacggagtccctgacagt
cgggacaactgccgcctggtgcctaaccccggccaggaggacgcggacagggacggcgtg
ggcgacgtgtgccaggacgactttgatgcagacaaggtggtagacaagatcgacgtgtgt
ccggagaacgctgaagtcacgctcaccgacttcagggccttccagacagtcgtgctggac
ccggagggtgacgcgcagattgaccccaactgggtggtgctcaaccagggaagggagatc
gtgcagacaatgaacagcgacccaggcctggctgtgggttacactgccttcaatggcgtg
gacttcgagggcacgttccatgtgaacacggtcacggatgacgactatgcgggcttcatc
tttggctaccaggacagctccagcttctacgtggtcatgtggaagcagatggagcaaacg
tattggcaggcgaaccccttccgtgctgtggccgagcctggcatccaactcaaggctgtg
aagtcttccacaggccccggggaacagctgcggaacgctctgtggcatacaggagacaca
gagtcccaggtgcggctgctgtggaaggacccgcgaaacgtgggttggaaggacaagaag
tcctatcgttggttcctgcagcaccggccccaagtgggctacatcagggtgcgattctat
gagggccctgagctggtggccgacagcaacgtggtcttggacacaaccatgcggggtggc
cgcctgggggtcttctgcttctcccaggagaacatcatctgggccaacctgcgttaccgc
tgcaatgacaccatcccagaggactatgagacccatcagctgcggcaagcctag

KEGG   Homo sapiens (human): 131873Help
Entry
131873            CDS       T01001                                 

Gene name
COL6A6
Definition
(RefSeq) collagen type VI alpha 6 chain
  KO
K06238  collagen, type VI, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04974  Protein digestion and absorption
hsa05165  Human papillomavirus infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    131873 (COL6A6)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    131873 (COL6A6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    131873 (COL6A6)
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    131873 (COL6A6)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    131873 (COL6A6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    131873 (COL6A6)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    131873 (COL6A6)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   131873 (COL6A6)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   131873 (COL6A6)
 Hyaluronan
  Extracellular matrix or blood plasma proteins
   131873 (COL6A6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: VWA VWA_2 Collagen VWA_CoxE Radical_SAM Integrin_beta DUF5035
Motif
Other DBs
NCBI-GeneID: 131873
NCBI-ProteinID: NP_001096078
OMIM: 616613
HGNC: 27023
Ensembl: ENSG00000206384
Vega: OTTHUMG00000159653
Pharos: A6NMZ7(Tdark)
UniProt: A6NMZ7
LinkDB All DBs
Position
3q22.1
AA seq 2263 aa AA seqDB search
MMLLILFLVIICSHISVNQDSGPEYADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIE
ADKYRVALAQYSDKLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFS
APANGRDKKQFPPILVVLASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMATS
QFHFNLRTVRDLSMFSQNMTHIIKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSING
SEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLS
PRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGV
TIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSE
RTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQY
ADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCH
LVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALK
DIRNQVVQEICTEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQ
IGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQYFSPTKGARP
NIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVEN
FDILQRIEDDLVFGICSPREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKAD
VGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFSDHMFT
EARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMA
GSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQPNDFKKMK
EFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNTHIG
AALREVEHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDV
DDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTAGESNCFVDVVVGFDVSTQEKG
QTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPKFEIYSEN
ILNSLKDITVKGPSLLNANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDEL
RKEGLNALITVALDGPADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAE
RTCCCLFCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKG
CYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPG
DRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHT
GPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRL
GSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIG
DPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRD
RSPGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHI
AILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPG
AHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQV
IVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDASRNMGSAE
FEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRS
KRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEI
LKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHPLDHHLVQLGRIHKPDHSYGVKFVK
SFINSIRRAINKYPPINLKIKCNRLNSIDPKQPPRPFRSFVPGPLKATLKEDVLQKAKFF
QDKKYLSRVARSGRDDAIQNFMRSTSHTFKNGRMIESAPKQHD
NT seq 6792 nt NT seq  +upstreamnt  +downstreamnt
atgatgttgctaattttgttcctcgtgataatttgttcccatatttctgtgaaccaagat
tccggccctgagtatgcagatgttgtgtttttggtggacagctctgatcgcctgggatcc
aagtccttcccatttgtgaaaatgttcatcaccaaaatgatcagcagtctccccatagag
gccgacaaataccgtgtggccctggcccagtacagtgataaacttcacagtgaattccac
ctgagcaccttcaaaggcaggagccccatgctgaaccacctaaggaagaactttggattc
attggcgggtccctgcagataggaaaggctcttcaggaggctcacaggacttatttctct
gcacccgcaaatgggagagacaagaaacagtttcccccaattctagtggtcctggcttca
tctgagtctgaggataatgtggaagaggcatcaaaggccctgcggaaagacggagtgaaa
atcatctctgtaggggtgcagaaagcttctgaggaaaacctgaaggccatggccacgtct
cagtttcatttcaaccttcggacagtcagagacctcagcatgttttcccaaaacatgaca
cacatcatcaaggatgtaataaagtacaaggagggagcagttgatgacatctttgtagaa
gcttgccaaggcccttctatggccgatgttgtgttcctattggatatgtcaatcaatgga
agtgaggagaactttgactatcttaaaggattcttggaagaaagtgtatctgcccttgac
ataaaggaaaattgcatgagggttggccttgtggcctatagcaatgagacaaaagtgata
aattcactgagcatgggcataaataagtcagaggttctccagcatatacagaacctttct
ccccgaactgggaaggcctatactggagctgccatcaaaaagctcaggaaggaagttttt
agtgcacggaatggcagtcggaagaatcagggggtgccccagattgccgtgctggtgacc
caccgagattcagaagacaacgtgacaaaagcagctgttaacctccgacgggagggtgtg
accatcttcaccctgggcatagagggcgccagcgacacccagttggaaaagatagcatcc
caccctgctgagcagtatgtctccaaactgaagaccttcgctgacctggctgctcacaac
cagacatttctgaagaagctgcggaaccaaataacacacacagtctctgtcttttcagag
aggactgaaacgctcaaatctggttgtgtggacactgaggaagcagacatctatctgctt
atcgatggctcagggagcacccaggccacagatttccatgaaatgaagacgttcctgtca
gaggtggtagggatgttcaacattgctccccataaggtgcgggttggggccgttcagtat
gctgacagctgggacttggaatttgagatcaataaatactccaacaagcaggatttggga
aaggccattgagaatatcaggcagatgggtgggaatacaaacacaggcgcagcactgaat
ttcacactgagtctgttgcaaaaagcaaagaagcagcgaggaaacaaagttccatgccac
cttgttgtcctgacaaatggcatgtccaaggatagcatcttggagcctgcaaacagactg
agagaagagcacatccgagtttatgctatcgggatcaaggaggccaaccaaacacagctg
agagaaattgcaggagaggaaaagagagtgtattacgtgcatgactttgatgcattgaaa
gacataagaaaccaagttgttcaagaaatctgtactgaagaagcttgcaaagagatgaaa
gctgacatcatgtttctggtggacagttctggaagtataggacctgaaaacttcagcaaa
atgaaaacatttatgaaaaacctggtgagcaagtctcagattggaccagatcgggtgcaa
attggtgtagtccagttcagcgacatcaataaggaagagtttcagctcaacagattcatg
tcccaaagcgacatttcaaatgcaatagaccaaatggctcacattggacaaaccaccctg
actggtagtgccctgagctttgtgtctcagtacttcagccccaccaagggcgcccggccc
aacatcagaaagtttctcatcctcatcacggatggtgaagctcaggacatagtaaaggaa
ccagcagtagtgcttcggcaagaaggtgtaatcatctattctgtgggagtgtttggctcc
aatgtcacccagcttgaggagatcagtgggaggcccgagatggttttttatgttgagaat
tttgacattctgcagcgcattgaagatgatcttgtttttggaatatgcagcccccgtgaa
gaatgcaagcggattgaagttttagacgttgtgtttgtcattgatagctctggcagtatt
gactatgatgagtataatatcatgaaggattttatgattggcttagtgaaaaaagctgat
gtgggcaagaatcaggtccggtttggggctctgaagtatgctgatgacccagaggtgctg
ttttatctggatgactttggcacaaaactggaggtaatttcagtgctccagaatgaccaa
gccatgggtggcagtacttatactgctgaggcactgggcttctcagaccacatgttcact
gaagcccggggcagccgcctgaacaagggggtcccccaagtcctcattgtgatcaccgat
ggggaatcccatgatgctgataaactcaatgccacggcaaaggccttgcgggacaaaggc
attcttgtcctggctgtggggattgatggtgccaatcccgtggagctgttagccatggca
ggatcaagcgacaagtacttcttcgtggagacttttggaggtctgaagggaatattttca
gatgtgacagccagtgtctgcaactcttcaaaagtagattgtgaaattgacaaagtagat
cttgttttccttatggatggttcaactagcattcagccaaatgacttcaagaaaatgaag
gaatttctggcatctgttgttcaagactttgatgtcagcctcaacagagtgcgaatagga
gcggcccagtttagcgatacctatcacccggagtttccactgggaactttcataggtgaa
aaagagatatcatttcagattgaaaacatcaagcagatctttggaaacacacacatcggt
gctgcactcagggaggtggaacattacttcaggccagacatgggcagcaggataaataca
ggtaccccacaggtgctgctggtccttacagatggccagtcccaagacgaggtggcccag
gccgcggaagccctgagacacagaggtatcgacatctactccgtgggcattggggatgtg
gatgaccagcagctcattcagatcaccgggactgcagagaaaaaactgacagtgcacaac
ttcgatgaactgaagaaggtcaataaaaggatcgttcgcaacatctgtaccacagcgggt
gaaagcaactgtttcgtggatgttgtggtgggatttgatgtctcaactcaggagaaaggg
cagactttgcttgaaggtcagccttggatggaaacctaccttcaagacatcttacgtgcc
atcagctccctcaatggagtaagctgtgaggtgggcacagagactcaggtcagtgtggct
tttcaagtgaccaatgccatggaaaaatattctcccaagtttgagatctacagtgaaaac
atactgaatagcttgaaggatataacagttaaaggaccatctcttctcaatgcaaacctc
ttggattctctatgggatacatttcagaataaatcagctgctcgaggaaaggtggtcctt
ttattttcagatggattggatgatgatgttgagaaacttgaacaaaaatctgatgaactt
agaaaagaaggcctgaatgccctcataactgttgctctggatggacctgctgattcaagt
gacttggctgatcttccctatattgaatttgggaaaggatttgagtacaggacacagctc
tctattggcatgagagaacttggaagccggctgtcaaagcagctggtcaatgttgctgaa
aggacatgctgctgtttgttctgcaagtgcattggaggagatggcacaatgggagatcct
ggaccaccagggaaaaggggacctccaggttttaaaggcagtgaaggctacctgggagag
gagggaatcgctggagaaagaggagcccctggaccagtgggagagcaaggtactaaggga
tgctatggcaccaaaggtcctaagggaaacagaggactaaatggacaggagggagaagtt
ggggaaaatggaattgacggattaaacggagaacagggtgataatggtcttcctggaaga
aaaggagaaaagggagatgagggatctcagggaagcccagggaagagagggactcctggt
gaccgtggagcaaagggcctgcgaggggatcccggagctcctggagttgacagtagcata
gaaggacccacaggcttgaaaggagaacgtggaagacaaggcagaagaggctggccaggc
ccccccgggacaccaggctccagaagaaagacagcagctcatggcagaaggggacataca
ggcccacagggaacagcaggcatcccaggaccagatggacttgaaggctccctgggactt
aagggccctcagggcccaagaggagaggctggtgtgaaaggagaaaaaggaggtgtggga
agtaaaggtccccaggggcctccaggacccggaggagaggcagggaatcaaggccgtttg
ggaagccaaggaaataaaggagaacctggagatctgggagaaaaaggagctgttggcttt
cctggtcctcgtggcttgcagggcaatgatggcagtccaggttatggtagtgtcggacgc
aagggagcaaagggacaagaaggattccctggagaaagtggacctaagggtgagattggg
gaccctggtggtccaggagagactgggctgaagggagctagaggcaaaatgatatctgct
gggcttccaggagagatgggatcccctggggaaccaggacctcctggacgtaagggtgtg
aaaggagccaaaggcttggcttcattttctacatgtgagctcattcagtatgtgcgagac
cgcagtcctggcaggcatggaaaaccggaatgcccagtgcacccaaccgagttggtgttt
gccctggaccactcccgggatgtcactgagcaggaatttgagcggatgaaggagatgatg
gctttcctggtgagagacattaaggtccgggagaacagctgccccgtgggagcgcacatc
gccatcctctcctataactcccacgccaggcaccttgtgcgcttctcagacgcctacaag
aagagtcaacttctcagagaaattgaaactattccttatgagagatcctctgccagcagg
gagattggcagagcaatgcggtttatttccaggaatgtcttcaagcggacgcttccgggg
gcacacacgagaaaaatcgccacatttttcagcagcggtcagtccgcggatgcccactcc
atcaccacggctgccatggagttcggcgcgcttgaaatcattcccgtggtgatcactttc
agcaacgtgccctcggtcaggcgcgcatttgcgattgacgacactggcacatttcaagta
atagtggttccctccggggccgactacataccagcattagagagactccagcggtgcact
ttctgctatgatgtgtgcaagccagatgcttcttgtgaccaagccagaccaccccctgtg
cagtcttacatggatgctgctttccttctggatgcctcccggaacatgggaagtgctgaa
tttgaagacataagagccttccttggagcactattagatcactttgaaatcaccccagag
ccggagacttctgtcactggagaccgggtggccctattgagccatgctccccccgacttc
ctacccaacactcagaagagtccagttagagctgagttcaatcttaccacctacagaagt
aagcgcctcatgaagaggcatgtgcacgagtcagttaaacaactaaatggagatgctttt
attggtcatgccttacagtggactctggacaatgtatttttaagtacacccaatctgaga
agaaacaaagtcatatttgtgatatctgctggggaaaccagccacttagatggggaaatc
ttaaagaaggaatccttgcgagccaaatgtcagggatatgccttatttgtgttttccctt
ggccctatttgggatgacaaggaactggaggatctcgccagccaccctttggatcaccac
ctggtccagcttggccgaattcataaacctgaccacagttatggtgtgaagtttgtgaag
tcctttataaactcaatcaggcgtgcaatcaacaaatatccaccaataaacttaaaaata
aagtgcaacagacttaactctatagatccaaagcagcccccacgaccattccgaagcttt
gttcctggaccacttaaagctaccctcaaagaagatgtattacagaaggcaaaattcttt
caagataaaaaatatctttcaagagtagcaagaagtggcagagatgatgctattcaaaat
tttatgagaagcacctcccatacctttaagaatggaaggatgatagaaagtgctcccaaa
caacatgattaa

KEGG   Homo sapiens (human): 22798Help
Entry
22798             CDS       T01001                                 

Gene name
LAMB4
Definition
(RefSeq) laminin subunit beta 4
  KO
K06245  laminin, beta 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    22798 (LAMB4)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    22798 (LAMB4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    22798 (LAMB4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    22798 (LAMB4)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    22798 (LAMB4)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    22798 (LAMB4)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    22798 (LAMB4)
   05145 Toxoplasmosis
    22798 (LAMB4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Laminin_EGF Laminin_N
Motif
Other DBs
NCBI-GeneID: 22798
NCBI-ProteinID: NP_001304975
OMIM: 616380
HGNC: 6491
Ensembl: ENSG00000091128
Vega: OTTHUMG00000154874
Pharos: A4D0S4(Tdark)
UniProt: A4D0S4 B7ZMJ6 B4DTV7
LinkDB All DBs
Position
7q31.1
AA seq 1761 aa AA seqDB search
MQFQLTLFLHLGWLSYSKAQDDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCIL
SYLEGEQKCFICDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDL
EALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGD
IVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDAL
LGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHN
TDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCE
DCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVA
GQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSY
VTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPA
PGYFFAPLNFYLYEAEEATTLQGLAPLGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFAR
VLPGAGLRFAVNNIPFPVDFTIAIHYETQSAADWTVQIVVNPPGGSEHCIPKTLQSKPQS
FALPAATRIMLLPTPICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSLGLIPQINSLEN
FCSKQDLDEYQLHNCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSS
CSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHG
EVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYG
NPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNP
RISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCR
RCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSC
DCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPIC
DPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLA
ANMEDKRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLKVKDYHDSVRRQIMQLNE
QLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSS
AEKKINETSSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPG
NVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLK
NQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIE
KVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAE
KAANILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELEL
AKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKT
STTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERKIQDLNLSRQAKADQLRILED
QVVAIKNEIVEQEKKYARCYS
NT seq 5286 nt NT seq  +upstreamnt  +downstreamnt
atgcaatttcaactgaccctttttttgcaccttgggtggctcagttactcaaaagctcaa
gatgactgcaacaggggtgcctgtcatcccaccactggtgatctcctggtgggcaggaac
acgcagcttatggcttcttctacctgtgggctgagcagagcccagaaatactgcatcctc
agttacctggagggggaacaaaaatgcttcatctgtgactctagatttccatatgatccg
tatgaccaacccaacagccacaccattgagaatgtcattgtaagttttgaaccagacaga
gaaaagaaatggtggcaatctgaaaatggtcttgatcatgtcagcatcagactggactta
gaggcattatttcggttcagccaccttatcctgacctttaagacttttcggcctgctgca
atgttagttgaacgttccacagactatggacacaactggaaagtgttcaaatattttgca
aaagactgtgccacttcctttcctaacatcacatctggccaggcccagggagtgggagac
attgtttgtgactccaaatactcggatattgaaccctcaacaggtggagaggttgtttta
aaagttttggatcccagttttgaaattgaaaacccttatagcccctacatccaagacctt
gtgacattgacaaacctgaggataaactttaccaagctccacacccttggggatgctttg
cttggaaggaggcaaaatgattcccttgataaatactactatgctctgtacgagatgatt
gttcggggaagctgcttttgcaatggccatgctagcgaatgtcgccctatgcagaagatg
cggggagatgttttcagccctcctggaatggttcacggtcagtgtgtgtgtcagcacaat
acagatggtccgaactgtgagagatgcaaggacttcttccaggatgctccttggaggcca
gctgcagacctccaggacaacgcttgcagatcgtgcagctgtaatagccactccagccgc
tgtcactttgacatgactacgtacctggcaagcggtggcctcagcgggggcgtgtgtgaa
gactgccagcacaacactgaggggcagcactgcgaccgctgcagacccctcttctacagg
gacccgctcaagaccatctcagatccctacgcgtgcattccttgtgaatgtgaccccgat
gggaccatatctggtggcatttgtgtgagccactctgatcctgccttagggtctgtggcc
ggccagtgcctttgtaaagagaacgtggaaggagccaaatgcgaccagtgcaaacccaac
cactacggactaagcgccaccgaccccctgggctgccagccctgcgactgtaaccccctt
gggagtctgccattcttgacctgtgatgtggatacaggccaatgcttgtgcctgtcatat
gtcaccggagcacactgcgaagaatgcactgttggatactggggcctgggaaatcatctc
catgggtgttctccctgtgactgtgatattggaggtgcttattctaacgtgtgctcaccc
aagaatgggcagtgtgaatgccgcccacatgtcactggccgtagctgctctgaaccagcc
cctggctacttctttgctcctttgaatttctatctctacgaggcagaggaagccacaaca
ctccaaggactggcgcctttgggctcggagacgtttggccagagtcctgctgttcacgtt
gttttaggagagccagttcctgggaaccctgttacatggactggacctggatttgccagg
gttctccctggggctggcttgagatttgctgtcaacaacattccctttcctgtggacttc
accattgccattcactatgaaacccagtctgcagctgactggactgtccagattgtggtg
aacccccctggagggagtgagcactgcatacccaagactctacagtcaaagcctcagtct
tttgccttaccagcggctacgagaatcatgctgcttcccacacccatctgtttagaacca
gatgtacaatattccatagatgtctatttttctcagcctttgcaaggagagtcccacgct
cattcacatgtcctggtggactctcttggccttattccccaaatcaattcattggagaat
ttctgcagcaagcaggacttagatgagtatcagcttcacaactgtgttgaaattgcctca
gcaatgggacctcaagtgctcccgggtgcctgtgaaaggctgatcatcagcatgtctgcc
aagctgcatgatggggctgtggcctgcaagtgtcacccccagggctcagtcggatccagc
tgcagccgacttggaggccagtgccagtgtaaacctcttgtggtcgggcgctgctgtgac
aggtgctcaactggaagctatgatttggggcatcacggctgtcacccatgtcactgccat
cctcaaggatcaaaggacactgtatgtgaccaagtaacaggacagtgcccctgccatgga
gaggtgtctggccgccgctgtgatcgctgcctggcaggctactttggatttcccagctgc
cacccttgcccttgtaataggtttgctgaactttgtgatcctgagacagggtcatgcttc
aattgtggaggctttacaactggcagaaactgtgaaaggtgtattgatggttactatgga
aatccttcttcaggacagccctgtcgtccttgcctgtgtccagatgatccctcaagcaat
cagtattttgcccattcctgttatcagaatctgtggagctcagatgtaatctgcaattgt
cttcaaggttatacgggtactcagtgtggagaatgctctactggtttctatggaaatcca
agaatttcaggagcaccttgccaaccatgtgcctgcaacaacaacatagatgtaaccgat
ccagagtcctgcagccgggtaacaggggagtgccttcgatgtttgcacaacactcagggc
gcaaactgccagctctgcaaaccaggtcactatggatcagccctcaatcagacctgcaga
agatgctcctgccatgcttccggcgtgagtcccatggagtgtccccctggtgggggagct
tgcctctgtgaccctgtcactggtgcatgtccttgtctgccgaatgtcacaggcctggcc
tgtgaccgttgtgctgatggatactggaatctggtccctggcagaggatgtcagtcatgt
gactgtgaccctaggacctctcaaagtagccactgtgaccagcttacaggccagtgtccg
tgtaaattaggttacggcgggaaacgttgcagtgagtgccaggaaaattattatggtgat
ccacctgggcgatgcattccatgtgattgtaacagggcaggtacccagaagcccatctgt
gatccagacacaggcatgtgccgctgccgggagggtgtcagcggccagagatgtgatcgc
tgtgcccggggacacagccaggaattccctacttgtcttcaatgtcacttgtgctttgat
cagtgggaccacaccatttcttccctctccaaagcggtgcaagggttaatgagactggct
gctaacatggaagataaaagagagaccctgcctgtctgtgaggcagacttcaaagacctc
agagggaacgtgtctgaaatagaaaggattttgaaacatcctgttttcccatctgggaaa
ttcttaaaagtcaaggattatcatgactctgttagaagacaaatcatgcagctaaatgaa
caactgaaagcagtgtatgaatttcaagatctgaaagatacaatagaaagagcaaagaat
gaagcagacctcttacttgaagaccttcaggaagaaattgatttgcaatccagtgtcctt
aatgcaagcattgcggactcctcagaaaacatcaagaaatattatcacatatcatcatct
gctgaaaagaaaattaatgaaactagttccaccattaatacctctgcaaatacaaggaat
gacttacttaccatcttagatacactaacctcaaaaggaaacttgtcattggaaagatta
aagcagattaagataccagatatccaaatattgaatgaaaaggtgtgcggagatccagga
aatgtgccatgtgtgcccttgccctgtggcggtgctctctgcacgggccggaaggggcac
aggaagtgtaggggtcccggctgtcacggctccctgaccctctcaacgaatgccctccaa
aaagcccaggaagcaaaatccattattcgtaatttggacaaacaggttcgtgggttgaaa
aatcagatcgaaagtataagtgaacaggcagaagtctccaaaaacaatgccttacagctg
agggaaaaactgggaaatataagaaaccaaagtgactctgaagaagaaaacatcaatctt
ttcatcaaaaaagtgaaaaactttttgttagaggaaaacgtgcctccagaagacatcgag
aaggttgcgaatggtgtgcttgacattcacctaccaattccatcccaaaatctaaccgat
gaacttgtcaaaatacagaaacatatgcaactctgtgaggattacaggacagatgaaaac
aggttaaatgaagaagcagatggagcccaaaagcttttggtgaaggccaaagcagctgag
aaagcagcaaatattctattaaatcttgacaaaacattgaaccagttacaacaagctcaa
atcactcaaggacgggcaaactctaccattacacagctgactgccaatataacaaaaata
aaaaagaatgtgctgcaggctgaaaatcaaaccagggaaatgaagagtgagctggagtta
gcaaagcagcgatcagggctggaggatggactttccctgctgcagaccaagttgcaaagg
catcaagaccacgctgtcaatgcgaaagttcaggctgaatctgcccaacaccaggctggg
agtcttgagaaggaatttgttgagctgaaaaaacaatatgctattctccaacgtaagaca
agcactacaggactaacaaaggagacattaggaaaagttaaacagctaaaagatgcggca
gaaaaattggctggagatacagaggccaagataagaagaataacagatttagaaaggaaa
atccaagatttgaatctaagtagacaagcaaaagctgatcaactgagaatattggaagat
caagttgttgccattaaaaatgaaattgttgaacaagaaaaaaaatatgctaggtgctat
agctag

KEGG   Homo sapiens (human): 2335Help
Entry
2335              CDS       T01001                                 

Gene name
FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF, SMDCF
Definition
(RefSeq) fibronectin 1
  KO
K05717  fibronectin 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04810  Regulation of actin cytoskeleton
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa05100  Bacterial invasion of epithelial cells
hsa05135  Yersinia infection
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05205  Proteoglycans in cancer
hsa05222  Small cell lung cancer
Network
nt06135  Cytoskeletal regulation (virus)
nt06167  Human cytomegalovirus (HCMV)
  Element
N00393  ITGA/B-RhoA signaling pathway
Disease
H01260  Glomerulopathy with fibronectin deposits
H02185  Spondylometaphyseal dysplasia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    2335 (FN1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    2335 (FN1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    2335 (FN1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    2335 (FN1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2335 (FN1)
   05205 Proteoglycans in cancer
    2335 (FN1)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    2335 (FN1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    2335 (FN1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    2335 (FN1)
   05100 Bacterial invasion of epithelial cells
    2335 (FN1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    2335 (FN1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    2335 (FN1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    2335 (FN1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2335 (FN1)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    2335 (FN1)
Membrane trafficking [BR:hsa04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   ER-Golgi intermediate compartment (ERGIC) proteins
    2335 (FN1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   2335 (FN1)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   2335 (FN1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: fn3 fn1 Pur_ac_phosph_N fn2 DUF2369 MG4
Motif
Other DBs
NCBI-GeneID: 2335
NCBI-ProteinID: NP_002017
OMIM: 135600
HGNC: 3778
Ensembl: ENSG00000115414
Vega: OTTHUMG00000133054
Pharos: P02751(Tchem)
UniProt: P02751 Q6MZF4 Q6N084
LinkDB All DBs
Structure
PDB: 

Position
2q35
AA seq 2355 aa AA seqDB search
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP
DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA
QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT
SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT
IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL
VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ
KSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTS
GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE
YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG
NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC
HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE
YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC
FMPLDVQADREDSRE
NT seq 7068 nt NT seq  +upstreamnt  +downstreamnt
atgcttaggggtccggggcccgggctgctgctgctggccgtccagtgcctggggacagcg
gtgccctccacgggagcctcgaagagcaagaggcaggctcagcaaatggttcagccccag
tccccggtggctgtcagtcaaagcaagcccggttgttatgacaatggaaaacactatcag
ataaatcaacagtgggagcggacctacctaggcaatgcgttggtttgtacttgttatgga
ggaagccgaggttttaactgcgagagtaaacctgaagctgaagagacttgctttgacaag
tacactgggaacacttaccgagtgggtgacacttatgagcgtcctaaagactccatgatc
tgggactgtacctgcatcggggctgggcgagggagaataagctgtaccatcgcaaaccgc
tgccatgaagggggtcagtcctacaagattggtgacacctggaggagaccacatgagact
ggtggttacatgttagagtgtgtgtgtcttggtaatggaaaaggagaatggacctgcaag
cccatagctgagaagtgttttgatcatgctgctgggacttcctatgtggtcggagaaacg
tgggagaagccctaccaaggctggatgatggtagattgtacttgcctgggagaaggcagc
ggacgcatcacttgcacttctagaaatagatgcaacgatcaggacacaaggacatcctat
agaattggagacacctggagcaagaaggataatcgaggaaacctgctccagtgcatctgc
acaggcaacggccgaggagagtggaagtgtgagaggcacacctctgtgcagaccacatcg
agcggatctggccccttcaccgatgttcgtgcagctgtttaccaaccgcagcctcacccc
cagcctcctccctatggccactgtgtcacagacagtggtgtggtctactctgtggggatg
cagtggctgaagacacaaggaaataagcaaatgctttgcacgtgcctgggcaacggagtc
agctgccaagagacagctgtaacccagacttacggtggcaactcaaatggagagccatgt
gtcttaccattcacctacaatggcaggacgttctactcctgcaccacagaagggcgacag
gacggacatctttggtgcagcacaacttcgaattatgagcaggaccagaaatactctttc
tgcacagaccacactgttttggttcagactcgaggaggaaattccaatggtgccttgtgc
cacttccccttcctatacaacaaccacaattacactgattgcacttctgagggcagaaga
gacaacatgaagtggtgtgggaccacacagaactatgatgccgaccagaagtttgggttc
tgccccatggctgcccacgaggaaatctgcacaaccaatgaaggggtcatgtaccgcatt
ggagatcagtgggataagcagcatgacatgggtcacatgatgaggtgcacgtgtgttggg
aatggtcgtggggaatggacatgcattgcctactcgcagcttcgagatcagtgcattgtt
gatgacatcacttacaatgtgaacgacacattccacaagcgtcatgaagaggggcacatg
ctgaactgtacatgcttcggtcagggtcggggcaggtggaagtgtgatcccgtcgaccaa
tgccaggattcagagactgggacgttttatcaaattggagattcatgggagaagtatgtg
catggtgtcagataccagtgctactgctatggccgtggcattggggagtggcattgccaa
cctttacagacctatccaagctcaagtggtcctgtcgaagtatttatcactgagactccg
agtcagcccaactcccaccccatccagtggaatgcaccacagccatctcacatttccaag
tacattctcaggtggagacctaaaaattctgtaggccgttggaaggaagctaccatacca
ggccacttaaactcctacaccatcaaaggcctgaagcctggtgtggtatacgagggccag
ctcatcagcatccagcagtacggccaccaagaagtgactcgctttgacttcaccaccacc
agcaccagcacacctgtgaccagcaacaccgtgacaggagagacgactcccttttctcct
cttgtggccacttctgaatctgtgaccgaaatcacagccagtagctttgtggtctcctgg
gtctcagcttccgacaccgtgtcgggattccgggtggaatatgagctgagtgaggaggga
gatgagccacagtacctggatcttccaagcacagccacttctgtgaacatccctgacctg
cttcctggccgaaaatacattgtaaatgtctatcagatatctgaggatggggagcagagt
ttgatcctgtctacttcacaaacaacagcgcctgatgcccctcctgacccgactgtggac
caagttgatgacacctcaattgttgttcgctggagcagaccccaggctcccatcacaggg
tacagaatagtctattcgccatcagtagaaggtagcagcacagaactcaaccttcctgaa
actgcaaactccgtcaccctcagtgacttgcaacctggtgttcagtataacatcactatc
tatgctgtggaagaaaatcaagaaagtacacctgttgtcattcaacaagaaaccactggc
accccacgctcagatacagtgccctctcccagggacctgcagtttgtggaagtgacagac
gtgaaggtcaccatcatgtggacaccgcctgagagtgcagtgaccggctaccgtgtggat
gtgatccccgtcaacctgcctggcgagcacgggcagaggctgcccatcagcaggaacacc
tttgcagaagtcaccgggctgtcccctggggtcacctattacttcaaagtctttgcagtg
agccatgggagggagagcaagcctctgactgctcaacagacaaccaaactggatgctccc
actaacctccagtttgtcaatgaaactgattctactgtcctggtgagatggactccacct
cgggcccagataacaggataccgactgaccgtgggccttacccgaagaggacagcccagg
cagtacaatgtgggtccctctgtctccaagtacccactgaggaatctgcagcctgcatct
gagtacaccgtatccctcgtggccataaagggcaaccaagagagccccaaagccactgga
gtctttaccacactgcagcctgggagctctattccaccttacaacaccgaggtgactgag
accaccattgtgatcacatggacgcctgctccaagaattggttttaagctgggtgtacga
ccaagccagggaggagaggcaccacgagaagtgacttcagactcaggaagcatcgttgtg
tccggcttgactccaggagtagaatacgtctacaccatccaagtcctgagagatggacag
gaaagagatgcgccaattgtaaacaaagtggtgacaccattgtctccaccaacaaacttg
catctggaggcaaaccctgacactggagtgctcacagtctcctgggagaggagcaccacc
ccagacattactggttatagaattaccacaacccctacaaacggccagcagggaaattct
ttggaagaagtggtccatgctgatcagagctcctgcacttttgataacctgagtcccggc
ctggagtacaatgtcagtgtttacactgtcaaggatgacaaggaaagtgtccctatctct
gataccatcatcccagctgttcctcctcccactgacctgcgattcaccaacattggtcca
gacaccatgcgtgtcacctgggctccacccccatccattgatttaaccaacttcctggtg
cgttactcacctgtgaaaaatgaggaagatgttgcagagttgtcaatttctccttcagac
aatgcagtggtcttaacaaatctcctgcctggtacagaatatgtagtgagtgtctccagt
gtctacgaacaacatgagagcacacctcttagaggaagacagaaaacaggtcttgattcc
ccaactggcattgacttttctgatattactgccaactcttttactgtgcactggattgct
cctcgagccaccatcactggctacaggatccgccatcatcccgagcacttcagtgggaga
cctcgagaagatcgggtgccccactctcggaattccatcaccctcaccaacctcactcca
ggcacagagtatgtggtcagcatcgttgctcttaatggcagagaggaaagtcccttattg
attggccaacaatcaacagtttctgatgttccgagggacctggaagttgttgctgcgacc
cccaccagcctactgatcagctgggatgctcctgctgtcacagtgagatattacaggatc
acttacggagagacaggaggaaatagccctgtccaggagttcactgtgcctgggagcaag
tctacagctaccatcagcggccttaaacctggagttgattataccatcactgtgtatgct
gtcactggccgtggagacagccccgcaagcagcaagccaatttccattaattaccgaaca
gaaattgacaaaccatcccagatgcaagtgaccgatgttcaggacaacagcattagtgtc
aagtggctgccttcaagttcccctgttactggttacagagtaaccaccactcccaaaaat
ggaccaggaccaacaaaaactaaaactgcaggtccagatcaaacagaaatgactattgaa
ggcttgcagcccacagtggagtatgtggttagtgtctatgctcagaatccaagcggagag
agtcagcctctggttcagactgcagtaaccaacattgatcgccctaaaggactggcattc
actgatgtggatgtcgattccatcaaaattgcttgggaaagcccacaggggcaagtttcc
aggtacagggtgacctactcgagccctgaggatggaatccatgagctattccctgcacct
gatggtgaagaagacactgcagagctgcaaggcctcagaccgggttctgagtacacagtc
agtgtggttgccttgcacgatgatatggagagccagcccctgattggaacccagtccaca
gctattcctgcaccaactgacctgaagttcactcaggtcacacccacaagcctgagcgcc
cagtggacaccacccaatgttcagctcactggatatcgagtgcgggtgacccccaaggag
aagaccggaccaatgaaagaaatcaaccttgctcctgacagctcatccgtggttgtatca
ggacttatggtggccaccaaatatgaagtgagtgtctatgctcttaaggacactttgaca
agcagaccagctcagggagttgtcaccactctggagaatgtcagcccaccaagaagggct
cgtgtgacagatgctactgagaccaccatcaccattagctggagaaccaagactgagacg
atcactggcttccaagttgatgccgttccagccaatggccagactccaatccagagaacc
atcaagccagatgtcagaagctacaccatcacaggtttacaaccaggcactgactacaag
atctacctgtacaccttgaatgacaatgctcggagctcccctgtggtcatcgacgcctcc
actgccattgatgcaccatccaacctgcgtttcctggccaccacacccaattccttgctg
gtatcatggcagccgccacgtgccaggattaccggctacatcatcaagtatgagaagcct
gggtctcctcccagagaagtggtccctcggccccgccctggtgtcacagaggctactatt
actggcctggaaccgggaaccgaatatacaatttatgtcattgccctgaagaataatcag
aagagcgagcccctgattggaaggaaaaagacagacgagcttccccaactggtaaccctt
ccacaccccaatcttcatggaccagagatcttggatgttccttccacagttcaaaagacc
cctttcgtcacccaccctgggtatgacactggaaatggtattcagcttcctggcacttct
ggtcagcaacccagtgttgggcaacaaatgatctttgaggaacatggttttaggcggacc
acaccgcccacaacggccacccccataaggcataggccaagaccatacccgccgaatgta
ggacaagaagctctctctcagacaaccatctcatgggccccattccaggacacttctgag
tacatcatttcatgtcatcctgttggcactgatgaagaacccttacagttcagggttcct
ggaacttctaccagtgccactctgacaggcctcaccagaggtgccacctacaacatcata
gtggaggcactgaaagaccagcagaggcataaggttcgggaagaggttgttaccgtgggc
aactctgtcaacgaaggcttgaaccaacctacggatgactcgtgctttgacccctacaca
gtttcccattatgccgttggagatgagtgggaacgaatgtctgaatcaggctttaaactg
ttgtgccagtgcttaggctttggaagtggtcatttcagatgtgattcatctagatggtgc
catgacaatggtgtgaactacaagattggagagaagtgggaccgtcagggagaaaatggc
cagatgatgagctgcacatgtcttgggaacggaaaaggagaattcaagtgtgaccctcat
gaggcaacgtgttatgatgatgggaagacataccacgtaggagaacagtggcagaaggaa
tatctcggtgccatttgctcctgcacatgctttggaggccagcggggctggcgctgtgac
aactgccgcagacctgggggtgaacccagtcccgaaggcactactggccagtcctacaac
cagtattctcagagataccatcagagaacaaacactaatgttaattgcccaattgagtgc
ttcatgcctttagatgtacaggctgacagagaagattcccgagagtaa

KEGG   Homo sapiens (human): 256076Help
Entry
256076            CDS       T01001                                 

Gene name
COL6A5, COL29A1, VWA4
Definition
(RefSeq) collagen type VI alpha 5 chain
  KO
K06238  collagen, type VI, alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04974  Protein digestion and absorption
hsa05165  Human papillomavirus infection
Disease
H01358  Atopic dermatitis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    256076 (COL6A5)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    256076 (COL6A5)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    256076 (COL6A5)
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    256076 (COL6A5)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    256076 (COL6A5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    256076 (COL6A5)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    256076 (COL6A5)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   256076 (COL6A5)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   256076 (COL6A5)
 Hyaluronan
  Extracellular matrix or blood plasma proteins
   256076 (COL6A5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: VWA VWA_2 Collagen VWA_3 VWA_CoxE Copine vWA-TerF-like
Motif
Other DBs
NCBI-GeneID: 256076
NCBI-ProteinID: NP_001265227
OMIM: 611916
HGNC: 26674
Ensembl: ENSG00000172752
Vega: OTTHUMG00000159712
Pharos: A8TX70(Tbio)
UniProt: A8TX70
LinkDB All DBs
Position
3q22.1
AA seq 2614 aa AA seqDB search
MKILLIIFVLIIWTETLADQSPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSL
PIEANKYRVALAQYSDEFHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRT
YFSAPINGRDRKQFPPILVVLASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAM
ATSHFHFNLRTIRDLSTFSQNMTQIIKDVTKYKEGAVDADMQVHFPISCQKDSLADLVFL
VDESLGTGGNLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQ
QIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALN
LRLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQ
ISTYAEQRNLDKTGCVDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVR
VGVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRM
SKVPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQ
NFDALKSIKNEVVREICAEKGCEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQI
GADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTH
SKGARLGAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSL
VFHVENFDHLKALERKLIFRVCALHDCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHL
VKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHA
NALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKANQKE
LEGMAGNKNNTIYVDNFDKLKDVFTLVQERMCTEAPEVCHLQEADVIFLCDGSDRVSNSD
FVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGG
FPRIDFALKKVSNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVL
GIGDVYKEHLLPITGNSEKIITFQDFDKLKNVDVKKRIIREICQSCGKTNCFMDIVVGFD
ISTHVQGQPLFQGHPQLESYLPGILEDISSIKGVSCGAGTEAQVSLAFKVNSDQGFPAKF
QIYQKAVFDSLLQVNVSGPTHLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNIML
ENQSDRLREAGLDALLVVSLNTTAHHEFSSFEFGKRFDYRTHLTIGMRELGKKLSQYLGN
IAERTCCCTFCKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKG
IAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRG
APGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQR
GLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGST
GRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKG
DIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRF
LREHSPCWKEKCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGAR
VAMVSYNSGTSYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYA
GANVRRVAVFFSNGQTASRSSIITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQV
IPVPPNGENQTLERLRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFK
AVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLL
MKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGENYERKEFVKMM
ALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHLIQLGRIHKPDLNYIAKFLKPFLYS
VRRGFNQYPPPMLEDACRLINLGGENIQNDGFQFVTELQEDFLGGNGFIGQELNSGRESP
FVKTEDNGSDYLVYLPSQMFEPQKLMINYEKDQKSAEIASLTSGHENYGRKEEPDHTYEP
GDVSLQEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLS
YSPPGYMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVG
TPNLRKNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASH
PLDHHLVQLGRTHKPDWNYIIKFVKPFVHLIRRAINKYPTEDMKATCVNMTSPNPENGGT
ENTVLLLPGIYEIKTENGDLFDEFDSQAQHLLVLGNNHSSGSETATDLMQKLYLLFSTEK
LAMKDKEKAHLEEISALVVDKQQEKEDGEDTRSS
NT seq 7845 nt NT seq  +upstreamnt  +downstreamnt
atgaagatcttgctaattatatttgtcctaatcatttggactgaaacattggcagaccag
agcccagggccaggccctgtgtatgcagatgtcgtgtttctggtggacagctccgatcac
ctgggacctaagtcattcccattcgtgaaaacgttcatcaacaaaatgatcaacagtctc
cccatagaggccaacaaataccgtgtagccctggcccagtacagcgacgagtttcacagt
gaattccatctgagcaccttcaaaggcagaagccccatgctgaaccacctcaagaagaac
tttcagttcattggcgggtccctgcagataggaaaggctcttcaggaggctcataggacc
tacttctctgcacccataaatgggagagacaggaaacagtttcccccaattttggtggtc
ctggcttcggctgagtctgaggatgaagtggaagaggcttcgaaagccctgcagaaagac
ggggtgaaaattatctccgtgggggtgcagaaagcttctgaggaaaatctgaaggccatg
gccacatcccatttccatttcaaccttcggacaatcagagacctcagcacattttcccaa
aacatgacacagatcatcaaggatgtaaccaagtataaggagggagccgtcgatgctgat
atgcaagttcacttccccatatcctgtcagaaagattcactcgctgacctcgtgttcctg
gtggatgagtcacttgggaccggaggaaatttaaggcatcttcagaccttccttgagaac
attaccagctccatggatgtgaaggaaaattgcatgcgacttggactgatgagttacagc
aatagtgccaagactatttcttttcttaaatcaagcacaacccaatctgaatttcagcag
caaatcaagaatctttctatccaagttgggaaatccaatacaggggctgccattgatcag
atgagaagagacggcttctcagagtcatatggcagcagaagagcacaaggagtgcctcag
attgcagttctggtcacccacagaccatcagatgatgaggtgcatgatgctgcgctgaac
cttcgactggaggatgtaaacgtgtttgccttgagcatccaaggggctaacaatacccag
ttagaagaaatagtgtcttatcctccagaacagacaatttccacgctgaagtcctatgca
gacttagaaacttacagtacaaagttcctgaaaaagctccagaatgaaatatggtcccaa
atttctacttatgctgaacaaaggaatcttgataaaactggctgtgtggatacaaaagag
gctgatatccacttcctcattgatggctcaagcagcatccaggagaaacagtttgagcaa
atcaagagatttatgttggaagtgacagaaatgtttagcattggcccagacaaagtccga
gttggagttgtgcagtattcagatgacacagaagtggaattttatatcactgactattct
aatgatattgacttaagaaaggctatttttaacattaagcaactaactggtggaacttat
actgggaaagctctggattacatactgcaaataataaaaaatggaatgaaggatagaatg
agcaaggttccctgttacctcattgtgttgactgatgggatgtccacagacagagtcgtg
gaacctgctaagagactaagggctgagcaaatcactgttcatgcagttggcattggggca
gctaataaaatagaactgcaagaaattgctgggaaagaagaaagggttagctttgggcag
aactttgatgctttgaaaagcataaaaaatgaagtcgttcgtgaaatctgcgctgaaaaa
ggatgtgaagacatgaaggccgacatcatgtttctggtggacagttcttggagtatagga
aatgaaaattttaggaaaatgaaaatcttcatgaaaaacctgttaactaaaattcaaatt
ggtgcagacaaaacccagattggtgttgttcagttcagtgataaaactaaggaagagttc
cagcttaatagatattttacacagcaagaaatttctgatgcaatagatagaatgtctctc
atcaatgaaggcactttaactggaaaggcactaaattttgtaggtcaatacttcacccac
tccaagggggcccgtttgggggccaaaaaatttctcatcctcatcacagatggagtagcg
caggatgatgtgagagatcctgctagaattcttcggggcaaagatgtgaccatcttctct
gtaggagtatacaatgccaatagatctcagctagaagagatcagtggggatagcagccta
gtttttcatgttgagaacttcgatcatctaaaggcactagaaaggaaacttatctttcgt
gtgtgtgctctccatgattgtaaaaggattacactactagacgttgtgtttgtgctggat
cattcaggtagcataaaaaaacaatatcaagatcacatgattaacctaactatccatttg
gtgaagaaagcagatgttggcagggaccgagttcagtttggagccctcaaatactctgac
caacctaacatccttttctaccttaatacatactcgaacagatcagcaataattgagaat
ctgcggaagcgcagggacactggagggaacacctacactgccaaggctctcaagcacgca
aatgccctgtttacagaggaacatggcagccgcatcaagcaaaatgtgaagcagatgctg
attgtcatcaccgatggggaatcccatgaccatgatcagctcaatgacacagcattggaa
ctgagaaacaaaggcatcaccatctttgcagtgggtgtaggaaaggccaaccaaaaggaa
cttgagggtatggcagggaataaaaacaatactatctatgtagataattttgacaaactg
aaagatgttttcacacttgttcaagaacgtatgtgtactgaagcaccagaggtctgtcat
cttcaggaagctgacgtgattttcctttgcgatggctctgacagggtatctaattcagat
tttgtaaccatgacaactttcttgtcagacttaatcgataattttgacattcagtctcaa
agaatgaaaattggtatggctcaatttggaagcaactaccagagtattattgagttgaaa
aactctctgactaaaacccagtggaagactcaaattcagaatgtctccaagagcggtgga
tttccaagaattgactttgcccttaaaaaagtgagcaatatgtttaatctacatgctggt
gggagaagaaatgctggtgtcccccaaactttggttgttatcacatctggagatcctcgc
tatgatgtggcagatgcagtaaaaaccctgaaggaccttggaatttgtgtcctggttttg
ggcataggagatgtttataaggaacatctcctgccaataacaggcaattctgaaaaaata
atcacttttcaagactttgataaattaaagaatgtggatgtgaaaaaaagaatcatccgt
gaaatctgccagagctgtgggaaaaccaattgctttatggacatagtggttgggtttgac
atctccactcatgtgcaggggcagcctttgttccagggccacccccagctggaatcctac
ctcccaggcatcttagaagacatcagctctatcaagggggtgagctgtggggctggcaca
gaggcacaggtgagcttggcgtttaaggtgaacagtgaccaaggattccctgccaagttc
caaatctatcagaaagcagtgtttgacagcttgctgcaagtcaacgtcagtgggccaact
catctgaacgcacagttcttgcggtctctttgggacacatttaaggataaatctgcatcc
cggggccaggtgctgcttattttttcagacggtctccagagtgaaagcaacataatgctt
gaaaatcaatcagacaggctcagagaagcaggacttgatgctctgctggtagtgtccctt
aacacaactgctcatcatgagttttctagctttgaatttggaaaaagattcgattacagg
actcatctgactattggaatgagagaactgggcaaaaaactatcacagtacctgggaaat
attgcagagaggacttgctgctgtacattctgcaaatgtccaggaattccaggacctcat
gggacccgaggactacaagccatgaagggttctcaaggtctgaaaggcagcagaggacac
aggggagaggatggaaaccctggagtacgaggagacacaggaccccaaggagacaaaggg
attgcaggatgtccaggggcgtggggtcagaagggactcaaaggattttctggacctaag
ggaggtcatggagacgatgggattgatggacttgatggggaagagggctgtcatggattt
cctggaataaaaggagaaaaaggtgatccaggatctcagggcagcccaggttccagaggt
gcccctgggcagtatggagagaagggcttcccaggggatccgggtaatccaggacaaaac
aataacatcaaaggacaaaagggctccaaaggagaacaaggaagacaaggtagaagtgga
cagaaaggggtgcaaggcagtcctagttccagaggcagcaggggaagagaaggtcaaagg
ggactccgaggtgtctcaggagaaccaggaaatcctggacctacaggcacattgggagct
gaaggattacaaggcccacaggggtcacagggaaatcctggcagaaaaggagaaaaagga
agccaggggcagaaaggacctcagggttctcctgggctaatgggagctaaagggagcact
ggaagacctggacttttggggaaaaaaggagagcctggacttcctggagatctagggcca
gtggggcaaactgggcagcgaggaagacagggagattctggcatcccaggctacggtcag
atgggacgaaaaggagtaaagggcccaagaggattccctggagatgcggggcagaagggt
gatattggtaatcctggaattcctgggggacctggacccaaaggatttaggggactagca
ctcactgtaggcttgaaaggtgaagagggatctcgaggactcccaggccctcctggacag
agaggcattaaaggcatggcagggcagcctgtatattctcaatgtgatctgatccggttt
ttgcgggaacatagtccttgctggaaagaaaaatgtccagcatatccaacagagctagta
tttgctctggacaattcctacgatgtcacagaagagagctttaataaaacacgggacatc
atcacttccattgtcaatgaccttaacatcagggaaaataactgtcctgtgggagcaaga
gttgccatggtttcctataactcaggcaccagctatctcatccgctggtctgactacaat
aggaagaagcagctcctccagcagctttcccaaataaaatatcaagacaccacagagccc
cgagatgttggtaatgcaatgaggtttgtgacccgcaacgtgttcaagcggacgtatgca
ggagccaacgtgaggagagttgctgtgttttttagcaatggtcaaacagccagtaggtca
tccatcatcacggccaccatggagtttagtgccctggatatcagtccaacagtctttgct
tttgatgagagagttttccttgaagcttttgggtttgacaacactggaacatttcaggtg
attccagttcctccaaatggggaaaatcaaacattagaaagacttcggcgctgtgcactt
tgctatgataaatgttttccaaatgcttgcattcgagaggctttcttacctgaagattca
tacatggatgtagtcttcctcatagacaattctcggaatatagcaaaggatgagtttaag
gctgtgaaagccttggtgagctcagtgattgacaacttcaacattgcttcagacccttta
atctcagactctggtgataggattgctttgttgagctattctccttgggaaagttccagg
agaaagatgggtacagtaaaaacagagtttgatttcatcacttatgacaaccaactccta
atgaagaatcacatccagacttccttccaacagctaaatggagaagcaacaattggtcgt
gccctactgtggaccactgaaaatctttttccagaaacaccctatctaagaaaacacaag
gtcatctttgtggtctcagctggagaaaattatgagagaaaagaatttgtaaaaatgatg
gctttgagggctaagtgtcaaggctacgtcatatttgtgatttctctgggctctacacgt
aaggatgacatggaggagttagccagctacccacttgatcaacacctgatacagcttggg
agaatacataaaccagatctgaattatattgcgaagttcttaaagccatttttatactcg
gtcaggcggggattcaatcagtacccaccaccgatgcttgaggatgcctgtagactcatc
aatttaggaggagagaatattcaaaatgatggtttccaatttgttactgagctacaagag
gattttttgggaggtaatggcttcattggccaagaattaaattctgggagagaatcacct
tttgtaaagacggaagacaatggaagtgactatttggtttaccttccaagccaaatgttt
gagccacaaaaattaatgatcaattatgaaaaagatcaaaaatctgcagaaattgcaagt
ctcacttctggacatgaaaattatggcagaaaagaagaaccagatcatacttatgaacct
ggagatgtctctcttcaagaatattacatggatgtggctttcctcatagatgcttcccaa
agagtaggaagtgatgagtttaaggaagtaaaagcttttataacctcagtgcttgattac
tttcacattgcccccactccactgacctccaccttaggagacagggttgctgtcctgagc
tactctcctccaggctatatgcctaacactgaagaatgccctgtctacctggaatttgat
ttggttacttataacagtatacaccaaatgaaacatcatctccaagactctcaacagctc
aatggagatgtttttattggccatgccttgcagtggacaattgacaatgtctttgtagga
acccccaatctgaggaaaaacaaagttatctttgtaatatctgctggcgaaaccaactct
ttagacaaagacgtcttaaggaatgtgtctctgagagccaagtgtcaaggctactccata
tttgtgttttcctttggccctaaacacaatgacaaagaattagaagaattagccagccac
cctctggatcatcacttggtccaacttggccgaacccacaagccagattggaactatatc
atcaagtttgtcaagccatttgtccatttaatcagacgtgccatcaacaaatatcccacc
gaagatatgaaagccacatgtgttaacatgacctctcccaacccagagaacggtggcaca
gaaaacactgtattacttcttcctgggatatatgaaataaagacagaaaatggtgatctg
tttgatgaatttgattcccaggcacaacatctccttgtattagggaacaatcatagtagt
ggttctgagacagctactgatttgatgcagaagttatatctgctcttttcaactgagaaa
ctggcaatgaaagacaaggaaaaagcacatttagaagaaatttcagctctagtggttgat
aaacagcaagaaaaagaagatggtgaagatacaaggtcatcatag

KEGG   Homo sapiens (human): 284217Help
Entry
284217            CDS       T01001                                 

Gene name
LAMA1, LAMA, PTBHS, S-LAM-alpha
Definition
(RefSeq) laminin subunit alpha 1
  KO
K05637  laminin, alpha 1/2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    284217 (LAMA1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    284217 (LAMA1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    284217 (LAMA1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    284217 (LAMA1)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    284217 (LAMA1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    284217 (LAMA1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    284217 (LAMA1)
   05145 Toxoplasmosis
    284217 (LAMA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Laminin_G_1 Laminin_EGF Laminin_G_2 Laminin_I Laminin_N Laminin_B Laminin_II Laminin_G_3 DUF1080
Motif
Other DBs
NCBI-GeneID: 284217
NCBI-ProteinID: NP_005550
OMIM: 150320
HGNC: 6481
Ensembl: ENSG00000101680
Vega: OTTHUMG00000133478
Pharos: P25391(Tbio)
UniProt: P25391
LinkDB All DBs
Position
18p11.31
AA seq 3075 aa AA seqDB search
MRGGVLLVLLLCVAAQCRQRGLFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGRP
VRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREYHWVTITLDLRQVFQVA
YVIIKAANAPRPGNWILERSLDGTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEV
ICTSYYSRLVPLEHGEIHTSLINGRPSADDLSPKLLEFTSARYIRLRLQRIRTLNADLMT
LSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGES
CNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGV
CINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHN
GKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGK
ACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMSGWLVTDLISPRKIP
SQQDALGGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETV
DSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPENFQDFHSKRQIDRDQLM
TVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGTSC
ESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEP
SRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPT
VPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCR
ACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVS
DGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHT
QGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLG
YRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALR
ADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPD
FLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLI
KGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYI
LIKASYGQGLQQSRISDISMEVGRKAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGY
HRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYG
KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQ
TPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDCVSCDDEC
VGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIKLE
GVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQT
LDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPL
EELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQ
EEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMS
QRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEESEELA
RDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALELSELRNKTNRFQ
ENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTS
ASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLS
EIKLLISQARKQAASIKVAVSADRDCIRAYQPQISSTNYNTLTLNVKTQEPDNLLFYLGS
STASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEM
SSNQKSPTKTSKSPGTANVLDVNNSTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGK
SIGLWNYIEREGKCRGCFGSSQNEDPSFHFDGSGYSVVEKSLPATVTQIIMLFNTFSPNG
LLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGV
LAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKN
LEISRSTFDLLRNSYGVRKGCLLEPIRSVSFLKGGYIELPPKSLSPESEWLVTFATTNSS
GIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSD
GQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMR
RSFHGCIKNLIFNLELLDFNSAVGHEQVDLDTCWLSERPKLAPDAEDSKLLPEPRAFPEQ
CVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIYYMAHQNQ
ADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPM
VTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDKDSPVSAF
TVNRCYAVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKVDAI
GLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNAVGA
ESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIKSPQVQSFDFSRAF
ELHGVFLHSCPGTES
NT seq 9228 nt NT seq  +upstreamnt  +downstreamnt
atgcgcgggggcgtgctcctggtcttgctgctgtgtgtcgccgcgcagtgccggcagaga
ggcctgtttcctgccattctcaatcttgccagcaatgctcacatcagcaccaatgccacc
tgtggcgagaaggggccggagatgttctgcaaacttgtggagcatgtgccaggtcggccc
gtccgaaacccacagtgccggatctgtgatggcaacagcgcaaaccccagagaacgccat
ccaatatcacatgccatagatggcaccaataactggtggcaaagtcccagcattcagaat
gggagagaatatcactgggtcacaatcactctggacttaagacaggtctttcaagttgca
tatgtcatcattaaagctgccaatgcccctcgacctggaaactggattttggagcgttct
ctggatggcaccacgttcagcccctggcagtattatgcagtcagcgactcagagtgtttg
tctcgttacaatataactccaagacgagggccacccacctacagggctgatgatgaagtg
atctgcacctcctattattccagattggtgccacttgagcatggagagattcatacatca
ctcatcaatggcagaccaagcgctgacgatctttcacccaagttgttggaattcacttct
gcacgatatattcgccttcgcttgcaacgcattagaacgctcaatgcagatctcatgacc
cttagccaccgggaacctaaagaactggatcctattgttaccagacgctattattattca
ataaaggacatttctgttggaggcatgtgtatctgctatggccatgctagtagctgccca
tgggatgaaactacaaagaaactgcagtgtcaatgtgagcataatacttgcggggagagc
tgtaacaggtgctgtcctgggtaccatcagcagccctggaggccgggaaccgtgtcctcc
ggcaatacatgtgaagcatgtaattgtcacaataaagccaaagactgttactatgatgaa
agtgttgcaaagcagaagaaaagtttgaatactgctggacagttcagaggaggaggggtt
tgcataaattgcttgcagaacaccatgggaatcaactgtgaaacctgtattgatggatat
tatagaccacacaaagtgtctccttatgaggatgagccttgccgcccctgtaattgtgac
cctgtggggtccctcagttctgtctgtattaaggatgacctccattctgacttacacaat
gggaagcagccaggtcagtgcccatgtaaggaaggttatacaggagaaaaatgtgatcgc
tgccaacttggctataaggattacccgacctgtgtctcctgtgggtgcaacccagtgggc
agtgccagtgatgagccctgcacagggccctgtgtttgtaaggaaaacgttgaggggaag
gcctgtgatcgctgcaagccaggattctataacttgaaggaaaaaaacccccggggctgc
tccgagtgcttctgctttggcgtttctgatgtctgcagcagcctctcttggcctgttggt
caggtaaacagtatgtccgggtggctggtcaccgacttgatcagtcccaggaagatcccg
tctcagcaagatgcactaggcgggcgccatcaggtcagcatcaacaacaccgcggtcatg
cagagactggctcccaagtactactgggcagcccccgaggcctaccttggaaataagctg
actgcgtttggcggattcctgaaatacacggtgtcctacgatattccggtagagacggta
gacagtaacctcatgtcgcatgctgacgtcatcattaagggaaacggactcactttaagc
acacaggctgagggtctgtcattgcagccttatgaagagtacctaaacgtggttagactt
gtgcctgaaaacttccaagattttcacagcaaaaggcagattgatcgtgaccagctgatg
actgtccttgccaatgtgacacatcttttgatcagagccaactacaattctgcaaaaatg
gctctttacaggttggagtccgtctctctggacatagccagctctaatgccatcgacctg
gtggtggccgctgatgtggagcactgtgaatgtccgcaaggctacacagggacctcctgt
gagtcgtgcctctctggctattaccgcgtggatggaatactctttggaggaatttgtcaa
ccctgtgaatgccacggccatgcagctgagtgtaatgttcacggcgtttgcattgcgtgt
gcgcacaacaccaccggcgtccactgtgagcagtgcttgcccggcttctacggggagcct
tcccgagggacacctggggactgccagccctgcgcctgccctctcaccatagcctccaac
aatttcagccccacctgccacctcaatgatggagatgaagtggtctgtgactggtgtgcc
ccgggctactcaggagcttggtgtgagagatgtgcagatggttactatggaaacccaaca
gtgcctggcgaatcttgtgttccctgtgactgcagcggcaacgtggacccctcggaggct
ggtcactgtgactcagtcaccggggagtgcctgaagtgcctggggaacacagatggcgcc
cactgtgaaaggtgtgctgacgggttctatggggacgctgtgacagccaagaactgccgc
gcctgtgaatgccatgtgaaaggctcccattctgccgtgtgccatcttgagaccgggctc
tgtgactgcaaaccaaacgtgactggacagcagtgtgaccagtgcttgcatggctattat
gggctggactcaggccatggctgccggccctgcaactgcagcgtggcaggctccgtgtca
gatggctgcacggatgaaggccagtgtcactgtgtcccaggtgtggcagggaaaaggtgt
gacaggtgtgcccatggcttctacgcctaccaggatggtagctgtacaccctgtgactgc
ccacacactcagaatacctgcgacccagaaactggagagtgtgtctgcccccctcacaca
cagggtgtgaagtgtgaagaatgtgaggatgggcactggggctacgatgcggaggtgggg
tgccaggcctgcaattgcagtctcgtggggtcgactcatcatcggtgcgatgtggtcacc
ggccattgccagtgcaagtcaaaatttggtggccgggcctgcgatcagtgttccttgggt
tacagagactttcccgactgtgttccctgtgactgtgacctgagggggacgtcgggggac
gcctgcaacctggagcagggtctctgcggctgtgtggaggaaaccggggcctgcccttgc
aaggaaaatgtctttggtcctcagtgcaacgaatgtcgagagggcaccttcgctctccgc
gcagacaaccccctgggctgcagcccgtgcttctgctccgggctgtcccacctctgctca
gagctggaggactacgtgaggaccccagtaacgctgggctccgatcagcctcttctgcgt
gtggtttctcagagtaacttgaggggcacgaccgagggggtttactaccaggcccccgac
ttcctgctggatgccgccaccgtccggcagcacatccgtgcagagccgttttactggcgg
ctgccgcagcagttccaaggagaccagctcatggcctatggtggcaaactgaagtacagc
gtggccttctattctttggatggcgtcggcacctccaattttgagcctcaagttctcatc
aaaggtggtcggatcagaaagcaagtcatttacatggatgcaccagccccagagaatgga
gtgagacaggaacaagaagtagcaatgagagagaatttttggaaatattttaactctgtt
tctgaaaaacctgtcacgcgagaggattttatgtctgtcctcagcgatattgagtacatc
ctcatcaaggcatcgtatggtcaaggattacagcagagcagaatctcagacatttcaatg
gaggttggcagaaaggctgaaaagctgcacccagaagaagaggttgcatctcttttagag
aattgtgtctgtcctcctggcactgtgggattctcatgtcaggactgcgcccctgggtac
cacagagggaagctcccagcagggagtgacaggggaccacgccctctggttgctccttgt
gttccctgcagttgcaacaaccacagtgacacctgtgaccccaacaccgggaagtgtctg
aactgtggcgataacacagcaggtgaccattgtgatgtgtgtacttctggctactacggg
aaggtgactggctcagcaagtgactgtgctctgtgtgcctgtcctcacagccctcctgcc
agttttagtcccacttgtgtcttggaaggggaccacgatttccgttgtgacgcctgtctc
ctgggctatgaaggaaaacactgtgaaaggtgctcctcaagctattatgggaaccctcaa
acaccaggtggcagttgccagaagtgtgactgcaacccgcacggctctgtccacggtgac
tgtgaccgcacatctgggcagtgcgtttgcaggctgggggcctcggggctccggtgcgat
gagtgtgaaccgaggcacattctgatggaaacagattgtgtttcctgtgatgatgagtgt
gtaggtgtgctgctgaatgacttggatgagattggtgatgccgttctttctctgaacctc
actggcattatccctgtcccatatggaattttgtcaaacctggaaaatacaactaaatat
ctccaggaatctttattaaaagaaaatatgcaaaaggacctgggaaaaattaagcttgaa
ggtgttgcagaagaaacggacaacctgcaaaagaagctcactaggatgttagcgagtacc
caaaaggtgaatagggcaactgagagaatcttcaaggagagtcaagacctggccatagcc
attgagaggctgcagatgagcatcacagaaattatggaaaagacaactttaaatcagact
ttggatgaagatttcctactacccaattctactcttcagaacatgcaacagaatggtaca
tctttgctagaaatcatgcagataagagacttcacacagttgcaccaaaatgccaccctt
gaactcaaggctgctgaagatttattgtcacaaattcaggaaaattaccagaagccgctg
gaagaattggaggtattgaaagaagcagcaagccacgtcctttcaaagcacaacaatgaa
ctaaaggcggctgaggcgctcgtgagggaagctgaggcaaagatgcaggaaagcaaccac
ctgctgctcatggtcaatgctaatctgagagaattcagtgataaaaagctgcatgttcaa
gaagaacaaaatctgacctcagagctcattgtccaaggaagaggattgatagatgctgct
gctgcacaaacagatgctgtacaagatgctctagagcacttagaggatcaccaggataag
ctacttttatggtctgccaaaatcaggcaccacatagatgacctggtcatgcacatgtcc
caaaggaacgcagtcgacctggtctacagagctgaggaccatgccgctgagttccagaga
ctagcagatgttctgtacagtggccttgaaaacatcagaaatgtgtccctgaatgccacc
agtgcagcctatgtccattacaacatccagagcctgattgaagaatcggaggaactggcc
agagatgctcacaggactgtgactgagacgagcctgctctcagaatcccttgtttctaac
gggaaagcggccgtgcagcgcagctccagatttctaaaagaaggcaacaacctcagcagg
aagcttccaggtattgcattggaactgagtgaattgagaaataagacaaacagatttcaa
gagaatgctgttgaaattaccaggcaaaccaatgaatcactcttgatacttagagcaatt
cctaaaggtataagagacaagggagccaaaaccaaagagctggccacgtctgcaagccag
agcgcggtgagcacgctgagggacgtggcggggctgagccaggagctgctgaacacatct
gccagcctgtccagggtcaacaccacattacgagagacacaccagcttctgcaggactcc
accatggccactctgttggctggaagaaaagtcaaagacgtggaaattcaagccaacctt
ttgtttgatcggttgaagcctttgaagatgttagaggagaatctgagcagaaacctatca
gaaattaaactgttgatcagccaggcccgcaaacaagcagcttctattaaagtcgccgtg
tctgcagacagagattgcatccgggcctaccagcctcagatttcctctaccaactacaat
accttaacactaaatgttaagacacaggaacccgataatcttctcttctacctcggtagc
agcaccgcttctgatttccttgcagtggagatgcggcgagggagagtggccttcctgtgg
gacctgggctccgggtccacacgcttggagtttccagactttcccattgatgacaacaga
tggcacagtatccatgtagccagatttggaaacattggttcactgagtgtaaaggaaatg
agctcaaatcaaaagtcaccaacaaaaacaagtaaatcccctgggacagctaatgttctg
gatgtaaacaattcaacactcatgtttgttggaggtcttggaggacaaatcaagaaatct
cctgctgtgaaggttactcattttaaaggctgcttgggggaggccttcctgaatggaaaa
tccataggcctatggaactatattgaaagggaaggcaagtgccgtgggtgcttcggaagc
tcccagaatgaagacccttccttccattttgacgggagtgggtactctgtcgtggagaag
tcacttccggctaccgtgacccagataatcatgctttttaataccttttcacctaatgga
cttcttctctacctgggttcatacggcacaaaagactttttatccatcgagctgtttcgt
ggcagagtgaaggttatgactgacctgggttcaggacccattacccttttgacagacaga
cgttataacaatggaacctggtacaaaattgccttccagcgaaaccggaagcaaggagtg
ctagcagttatcgatgcctataacaccagtaataaagaaaccaagcagggcgagactccg
ggagcatcttctgacctcaaccgcctagacaaggacccgatttatgtgggtggattacca
aggtcaagagttgtaaggagaggtgtcaccaccaaaagctttgtgggctgcatcaagaac
ctggaaatatccagatcaacctttgacttactcagaaattcctatggagtgagaaaaggc
tgtttactggagcccatccggagtgttagcttcctgaaaggcggctacattgaattgcca
cccaaatctttgtcaccagaatcagaatggctggtaacatttgccaccacgaacagcagt
ggcatcatcctggctgccctcggcggggatgtggagaagcggggtgatcgtgaggaagca
cacgtgcccttcttttccgtcatgctgatcggaggcaacattgaggtacatgtcaatcct
ggggatgggacaggcctgagaaaagctctcctgcacgctcccacgggtacctgcagtgat
ggacaagcgcattccatctccttggtcaggaatcggagaattatcactgtccaattggat
gagaacaatcctgtggaaatgaagttgggcacattagtagaaagcaggacgataaatgtg
tccaatctgtacgtcgggggaattccagagggagaggggacgtcactgctcacaatgaga
agatcgttccatggctgtatcaaaaacctgatcttcaatttggaacttttggatttcaac
agtgcagttggccatgagcaagtcgacctggacacctgctggctgtcagaaaggcctaag
ctggctcccgatgcagaggacagcaagctcttgccagagccccgggcttttccagaacag
tgtgtggtggatgcagctctggagtacgttcccggcgctcaccagtttggtctcacacaa
aacagccatttcatcttgccttttaatcagtcggctgtcagaaagaagctctcggttgag
ctaagcatccgcacgttcgcctccagcggcctgatttactacatggctcatcagaaccaa
gcagactacgctgtgctccagctgcacgggggccgcctccacttcatgtttgaccttggc
aaaggcagaacaaaggtctctcaccctgcactgctcagtgatggcaagtggcacacggtc
aagacagactatgttaaaagaaaaggcttcataactgtcgacggccgagagtctcccatg
gtgactgtggtgggagatggaaccatgctggatgtggagggtttgttctacctaggaggc
ctgccctcccagtaccaggccaggaaaattggaaatatcacccacagcatccctgcctgc
attggggatgtgacggttaacagcaaacagctggacaaggacagcccggtgtctgccttc
acggtgaacaggtgctacgcagtggcccaggaaggaacatactttgacggaagcggatat
gcagctcttgtcaaagagggctacaaagtccagtcagatgtgaacatcacactggagttt
cgaacctcctcgcagaatggcgtcctcctggggatcagcactgccaaagtggatgccatt
ggactagagcttgtggacggcaaggtcttgttccatgtcaacaatggtgctggcaggata
acagctgcatatgagcccaaaaccgccactgtgctctgtgatggaaaatggcacactctt
caagctaacaaaagcaaacaccgtatcactctgattgttgacgggaacgcagttggcgct
gaaagtccacacacccagtctacctcagtggacaccaacaatcccatttatgttggtggc
tatcctgctggtgtgaagcaaaaatgcctgcgcagccagacctcgttccgcgggtgtttg
aggaagctagctctgattaagagcccgcaggtgcagtcctttgacttcagcagagcgttc
gaactgcacggagttttccttcattcctgtcctgggaccgagtcctga

KEGG   Homo sapiens (human): 3371Help
Entry
3371              CDS       T01001                                 

Gene name
TNC, 150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C
Definition
(RefSeq) tenascin C
  KO
K06252  tenascin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05165  Human papillomavirus infection
hsa05206  MicroRNAs in cancer
Disease
H00604  Deafness, autosomal dominant
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3371 (TNC)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3371 (TNC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3371 (TNC)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    3371 (TNC)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3371 (TNC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    3371 (TNC)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   3371 (TNC)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: fn3 Fibrinogen_C EGF_Tenascin EGF_2 EGF Pur_ac_phosph_N hEGF DUF2369 DUF4998 fn3_2 Polyketide_cyc2
Motif
Other DBs
NCBI-GeneID: 3371
NCBI-ProteinID: NP_002151
OMIM: 187380
HGNC: 5318
Ensembl: ENSG00000041982
Vega: OTTHUMG00000021010
Pharos: P24821(Tbio)
UniProt: P24821 Q4LE33 B4E1W8
LinkDB All DBs
Structure
PDB: 

Position
9q33.1
AA seq 2201 aa AA seqDB search
MGAMTQLLAGVFLAFLALATEGGVLKKVIRHKRQSGVNATLPEENQPVVFNHVYNIKLPV
GSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRINIPRRACGCAAAPDVK
ELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGW
KGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFE
GYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECV
CDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQ
CVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVN
GQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRC
VNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQG
RCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNN
LGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTH
EGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKF
KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE
ISLHIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIK
DVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLR
RVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTE
YGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS
LPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENL
TVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPY
TVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQ
EADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMG
NLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGT
PYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQ
VQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPE
IGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPP
STDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFL
VTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAE
PEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGL
REATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESF
RITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALD
GPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPA
TEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLV
YESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPF
PKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNW
KAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYK
LKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGD
NNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA
NT seq 6606 nt NT seq  +upstreamnt  +downstreamnt
atgggggccatgactcagctgttggcaggtgtctttcttgctttccttgccctcgctacc
gaaggtggggtcctcaagaaagtcatccggcacaagcgacagagtggggtgaacgccacc
ctgccagaagagaaccagccagtggtgtttaaccacgtttacaacatcaagctgccagtg
ggatcccagtgttcggtggatctggagtcagccagtggggagaaagacctggcaccgcct
tcagagcccagcgaaagctttcaggagcacacagtggatggggaaaaccagattgtcttc
acacatcgcatcaacatcccccgccgggcctgtggctgtgccgcagcccctgatgttaag
gagctgctgagcagactggaggagctggagaacctggtgtcttccctgagggagcaatgt
actgcaggagcaggctgctgtctccagcctgccacaggccgcttggacaccaggcccttc
tgtagcggtcggggcaacttcagcactgaaggatgtggctgtgtctgcgaacctggctgg
aaaggccccaactgctctgagcccgaatgtccaggcaactgtcaccttcgaggccggtgc
attgatgggcagtgcatctgtgacgacggcttcacgggcgaggactgcagccagctggct
tgccccagcgactgcaatgaccagggcaagtgcgtaaatggagtctgcatctgtttcgaa
ggctacgccggggctgactgcagccgtgaaatctgcccagtgccctgcagtgaggagcac
ggcacatgtgtagatggcttgtgtgtgtgccacgatggctttgcaggcgatgactgcaac
aagcctctgtgtctcaacaattgctacaaccgtggacgatgcgtggagaatgagtgcgtg
tgtgatgagggtttcacgggcgaagactgcagtgagctcatctgccccaatgactgcttc
gaccggggccgctgcatcaatggcacctgctactgcgaagaaggcttcacaggtgaagac
tgcgggaaacccacctgcccacatgcctgccacacccagggccggtgtgaggaggggcag
tgtgtatgtgatgagggctttgccggtgtggactgcagcgagaagaggtgtcctgctgac
tgtcacaatcgtggccgctgtgtagacgggcggtgtgagtgtgatgatggtttcactgga
gctgactgtggggagctcaagtgtcccaatggctgcagtggccatggccgctgtgtcaat
gggcagtgtgtgtgtgatgagggctatactggggaggactgcagccagctacggtgcccc
aatgactgtcacagtcggggccgctgtgtcgagggcaaatgtgtatgtgagcaaggcttc
aagggctatgactgcagtgacatgagctgccctaatgactgtcaccagcacggccgctgt
gtgaatggcatgtgtgtttgtgatgacggctacacaggggaagactgccgggatcgccaa
tgccccagggactgcagcaacaggggcctctgtgtggacggacagtgcgtctgtgaggac
ggcttcaccggccctgactgtgcagaactctcctgtccaaatgactgccatggccagggt
cgctgtgtgaatgggcagtgcgtgtgccatgaaggatttatgggcaaagactgcaaggag
caaagatgtcccagtgactgtcatggccagggccgctgcgtggacggccagtgcatctgc
cacgagggcttcacaggcctggactgtggccagcactcctgccccagtgactgcaacaac
ttaggacaatgcgtctcgggccgctgcatctgcaacgagggctacagcggagaagactgc
tcagaggtgtctcctcccaaagacctcgttgtgacagaagtgacggaagagacggtcaac
ctggcctgggacaatgagatgcgggtcacagagtaccttgtcgtgtacacgcccacccac
gagggtggtctggaaatgcagttccgtgtgcctggggaccagacgtccaccatcatccag
gagctggagcctggtgtggagtactttatccgtgtatttgccatcctggagaacaagaag
agcattcctgtcagcgccagggtggccacgtacttacctgcacctgaaggcctgaaattc
aagtccatcaaggagacatctgtggaagtggagtgggatcctctagacattgcttttgaa
acctgggagatcatcttccggaatatgaataaagaagatgagggagagatcaccaaaagc
ctgaggaggccagagacctcttaccggcaaactggtctagctcctgggcaagagtatgag
atatctctgcacatagtgaaaaacaatacccggggccctggcctgaagagggtgaccacc
acacgcttggatgcccccagccagatcgaggtgaaagatgtcacagacaccactgccttg
atcacctggttcaagcccctggctgagatcgatggcattgagctgacctacggcatcaaa
gacgtgccaggagaccgtaccaccatcgatctcacagaggacgagaaccagtactccatc
gggaacctgaagcctgacactgagtacgaggtgtccctcatctcccgcagaggtgacatg
tcaagcaacccagccaaagagaccttcacaacaggcctcgatgctcccaggaatcttcga
cgtgtttcccagacagataacagcatcaccctggaatggaggaatggcaaggcagctatt
gacagttacagaattaagtatgcccccatctctggaggggaccacgctgaggttgatgtt
ccaaagagccaacaagccacaaccaaaaccacactcacaggtctgaggccgggaactgaa
tatgggattggagtttctgctgtgaaggaagacaaggagagcaatccagcgaccatcaac
gcagccacagagttggacacgcccaaggaccttcaggtttctgaaactgcagagaccagc
ctgaccctgctctggaagacaccgttggccaaatttgaccgctaccgcctcaattacagt
ctccccacaggccagtgggtgggagtgcagcttccaagaaacaccacttcctatgtcctg
agaggcctggaaccaggacaggagtacaatgtcctcctgacagccgagaaaggcagacac
aagagcaagcccgcacgtgtgaaggcatccactgaacaagcccctgagctggaaaacctc
accgtgactgaggttggctgggatggcctcagactcaactggaccgcagctgaccaggcc
tatgagcactttatcattcaggtgcaggaggccaacaaggtggaggcagctcggaacctc
accgtgcctggcagccttcgggctgtggacataccgggcctcaaggctgctacgccttat
acagtctccatctatggggtgatccagggctatagaacaccagtgctctctgctgaggcc
tccacaggggaaactcccaatttgggagaggtcgtggtggccgaggtgggctgggatgcc
ctcaaactcaactggactgctccagaaggggcctatgagtactttttcattcaggtgcag
gaggctgacacagtagaggcagcccagaacctcaccgtcccaggaggactgaggtccaca
gacctgcctgggctcaaagcagccactcattataccatcaccatccgcggggtcactcag
gacttcagcacaacccctctctctgttgaagtcttgacagaggaggttccagatatggga
aacctcacagtgaccgaggttagctgggatgctctcagactgaactggaccacgccagat
ggaacctatgaccagtttactattcaggtccaggaggctgaccaggtggaagaggctcac
aatctcacggttcctggcagcctgcgttccatggaaatcccaggcctcagggctggcact
ccttacacagtcaccctgcacggcgaggtcaggggccacagcactcgaccccttgctgta
gaggtcgtcacagaggatctcccacagctgggagatttagccgtgtctgaggttggctgg
gatggcctcagactcaactggaccgcagctgacaatgcctatgagcactttgtcattcag
gtgcaggaggtcaacaaagtggaggcagcccagaacctcacgttgcctggcagcctcagg
gctgtggacatcccgggcctcgaggctgccacgccttatagagtctccatctatggggtg
atccggggctatagaacaccagtactctctgctgaggcctccacagccaaagaacctgaa
attggaaacttaaatgtttctgacataactcccgagagcttcaatctctcctggatggct
accgatgggatcttcgagacctttaccattgaaattattgattccaataggttgctggag
actgtggaatataatatctctggtgctgaacgaactgcccatatctcagggctaccccct
agtactgattttattgtctacctctctggacttgctcccagcatccggaccaaaaccatc
agtgccacagccacgacagaggccctgccccttctggaaaacctaaccatttccgacatt
aatccctacgggttcacagtttcctggatggcatcggagaatgcctttgacagctttcta
gtaacggtggtggattctgggaagctgctggacccccaggaattcacactttcaggaacc
cagaggaagctggagcttagaggcctcataactggcattggctatgaggttatggtctct
ggcttcacccaagggcatcaaaccaagcccttgagggctgagattgttacagaagccgaa
ccggaagttgacaaccttctggtttcagatgccaccccagacggtttccgtctgtcctgg
acagctgatgaaggggtcttcgacaattttgttctcaaaatcagagataccaaaaagcag
tctgagccactggaaataaccctacttgcccccgaacgtaccagggacataacaggtctc
agagaggctactgaatacgaaattgaactctatggaataagcaaaggaaggcgatcccag
acagtcagtgctatagcaacaacagccatgggctccccaaaggaagtcattttctcagac
atcactgaaaattcggctactgtcagctggagggcacccacagcccaagtggagagcttc
cggattacctatgtgcccattacaggaggtacaccctccatggtaactgtggacggaacc
aagactcagaccaggctggtgaaactcatacctggcgtggagtaccttgtcagcatcatc
gccatgaagggctttgaggaaagtgaacctgtctcagggtcattcaccacagctctggat
ggcccatctggcctggtgacagccaacatcactgactcagaagccttggccaggtggcag
ccagccattgccactgtggacagttatgtcatctcctacacaggcgagaaagtgccagaa
attacacgcacggtgtccgggaacacagtggagtatgctctgaccgacctcgagcctgcc
acggaatacacactgagaatctttgcagagaaagggccccagaagagctcaaccatcact
gccaagttcacaacagacctcgattctccaagagacttgactgctactgaggttcagtcg
gaaactgccctccttacctggcgacccccccgggcatcagtcaccggttacctgctggtc
tatgaatcagtggatggcacagtcaaggaagtcattgtgggtccagataccacctcctac
agcctggcagacctgagcccatccacccactacacagccaagatccaggcactcaatggg
cccctgaggagcaatatgatccagaccatcttcaccacaattggactcctgtaccccttc
cccaaggactgctcccaagcaatgctgaatggagacacgacctctggcctctacaccatt
tatctgaatggtgataaggctgaggcgctggaagtcttctgtgacatgacctctgatggg
ggtggatggattgtgttcctgagacgcaaaaacggacgcgagaacttctaccaaaactgg
aaggcatatgctgctggatttggggaccgcagagaagaattctggcttgggctggacaac
ctgaacaaaatcacagcccaggggcagtacgagctccgggtggacctgcgggaccatggg
gagacagcctttgctgtctatgacaagttcagcgtgggagatgccaagactcgctacaag
ctgaaggtggaggggtacagtgggacagcaggtgactccatggcctaccacaatggcaga
tccttctccacctttgacaaggacacagattcagccatcaccaactgtgctctgtcctac
aaaggggctttctggtacaggaactgtcaccgtgtcaacctgatggggagatatggggac
aataaccacagtcagggcgttaactggttccactggaagggccacgaacactcaatccag
tttgctgagatgaagctgagaccaagcaacttcagaaatcttgaaggcaggcgcaaacgg
gcataa

KEGG   Homo sapiens (human): 3381Help
Entry
3381              CDS       T01001                                 

Gene name
IBSP, BNSP, BSP, BSP-II, SP-II
Definition
(RefSeq) integrin binding sialoprotein
  KO
K06253  integrin binding sialoprotein
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05165  Human papillomavirus infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3381 (IBSP)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3381 (IBSP)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3381 (IBSP)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3381 (IBSP)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: BSP_II Utp14 Mpp10
Motif
Other DBs
NCBI-GeneID: 3381
NCBI-ProteinID: NP_004958
OMIM: 147563
HGNC: 5341
Ensembl: ENSG00000029559
Vega: OTTHUMG00000130600
Pharos: P21815(Tbio)
UniProt: P21815
LinkDB All DBs
Position
4q22.1
AA seq 317 aa AA seqDB search
MKTALILLSILGMACAFSMKNLHRRVKIEDSEENGVFKYRPRYYLYKHAYFYPHLKRFPV
QGSSDSSEENGDDSSEEEEEEEETSNEGENNEESNEDEDSEAENTTLSATTLGYGEDATP
GTGYTGLAAIQLPKKAGDITNKATKEKESDEEEEEEEEGNENEESEAEVDENEQGINGTS
TNSTEAENGNGSSGGDNGEEGEEESVTGANAEDTTETGRQGKGTSKTTTSPNGGFEPTTP
PQVYRTTSPPFGKTTTVEYEGEYEYTGANEYDNGYEIYESENGEPRGDNYRAYEDEYSYF
KGQGYDGYDGQNYYHHQ
NT seq 954 nt NT seq  +upstreamnt  +downstreamnt
atgaagactgctttaattttgctcagcattttgggaatggcctgtgctttctcaatgaaa
aatttgcatcgaagagtcaaaatagaggattctgaagaaaatggggtctttaagtacagg
ccacgatattatctttacaagcatgcctacttttatcctcatttaaaacgatttccagtt
cagggcagtagtgactcatccgaagaaaatggagatgacagttcagaagaggaggaggaa
gaagaggagacttcaaatgaaggagaaaacaatgaagaatcgaatgaagatgaagactct
gaggctgagaataccacactttctgctacaacactgggctatggagaggacgccacgcct
ggcacagggtatacagggttagctgcaatccagcttcccaagaaggctggggatataaca
aataaagctacaaaagagaaggaaagtgatgaagaagaagaggaggaagaggaaggaaat
gaaaacgaagaaagcgaagcagaagtggatgaaaacgaacaaggcataaacggcaccagt
accaacagcacagaggcagaaaacggcaacggcagcagcggaggagacaatggagaagaa
ggggaagaagaaagtgtcactggagccaatgcagaagacaccacagagaccggaaggcag
ggcaagggcacctcgaagacaacaacctctccaaatggtgggtttgaacctacaacccca
ccacaagtctatagaaccacttccccaccttttgggaaaaccaccaccgttgaatacgag
ggggagtacgaatacacgggcgccaatgaatacgacaatggatatgaaatctatgaaagt
gagaacggggaacctcgtggggacaattaccgagcctatgaagatgagtacagctacttt
aaaggacaaggctacgatggctatgatggtcagaattactaccaccaccagtga

KEGG   Homo sapiens (human): 3908Help
Entry
3908              CDS       T01001                                 

Gene name
LAMA2, LAMM, MDC1A
Definition
(RefSeq) laminin subunit alpha 2
  KO
K05637  laminin, alpha 1/2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
hsa05410  Hypertrophic cardiomyopathy (HCM)
hsa05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
hsa05414  Dilated cardiomyopathy (DCM)
hsa05416  Viral myocarditis
Disease
H01958  Merosin-deficient congenital muscular dystrophy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3908 (LAMA2)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3908 (LAMA2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3908 (LAMA2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3908 (LAMA2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    3908 (LAMA2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy (HCM)
    3908 (LAMA2)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    3908 (LAMA2)
   05414 Dilated cardiomyopathy (DCM)
    3908 (LAMA2)
   05416 Viral myocarditis
    3908 (LAMA2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3908 (LAMA2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    3908 (LAMA2)
   05145 Toxoplasmosis
    3908 (LAMA2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Laminin_G_1 Laminin_EGF Laminin_G_2 Laminin_I Laminin_N Laminin_B Laminin_II Laminin_G_3 DUF948
Motif
Other DBs
NCBI-GeneID: 3908
NCBI-ProteinID: NP_000417
OMIM: 156225
HGNC: 6482
Ensembl: ENSG00000196569
Vega: OTTHUMG00000015545
Pharos: P24043(Tbio)
UniProt: P24043 Q59H37
LinkDB All DBs
Structure
PDB: 

Position
6q22.33
AA seq 3122 aa AA seqDB search
MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS
ARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG
NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN
CHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNV
EGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDE
ALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFE
AREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRV
HRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKC
DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ
HHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRG
YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC
KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK
HLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGE
FIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIA
EDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA
NRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQ
TKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFN
ATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNE
AKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDK
ARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVK
NLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTYKP
EIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYP
DLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAMLF
VGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGT
IQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKV
SYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGL
DLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKG
CSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQ
TGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVD
ENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPV
SFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALL
IGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRN
GLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILD
VVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQR
GTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFH
VDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADT
NDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCP
AN
NT seq 9369 nt NT seq  +upstreamnt  +downstreamnt
atgccgggagccgccggggtcctcctccttctgctgctctccggaggcctcgggggcgta
caggcgcagcggccgcagcagcagcggcagtcacaggcacatcagcaaagaggtttattc
cctgctgtcctgaatcttgcttctaatgctcttatcacgaccaatgcaacatgtggagaa
aaaggacctgaaatgtactgcaaattggtagaacatgtccctgggcagcctgtgaggaac
ccgcagtgtcgaatctgcaatcaaaacagcagcaatccaaaccagagacacccgattaca
aatgctattgatggaaagaacacttggtggcagagtcccagtattaagaatggaatcgaa
taccattatgtgacaattaccctggatttacagcaggtgttccagatcgcgtatgtgatt
gtgaaggcagctaactccccccggcctggaaactggattttggaacgctctcttgatgat
gttgaatacaagccctggcagtatcatgctgtgacagacacggagtgcctaacgctttac
aatatttatccccgcactgggccaccgtcatatgccaaagatgatgaggtcatctgcact
tcattttactccaagatacaccccttagaaaatggagagattcacatctctttaatcaat
gggagaccaagtgccgatgatccttctccagaactgctagaatttacctccgctcgctat
attcgcctgagatttcagaggatccgcacactgaatgctgacttgatgatgtttgctcac
aaagacccaagagaaattgaccccattgtcaccagaagatattactactcggtcaaggat
atttcagttggagggatgtgcatctgctatggtcatgccagggcttgtccacttgatcca
gcgacaaataaatctcgctgtgagtgtgagcataacacatgtggcgatagctgtgatcag
tgctgtccaggattccatcagaaaccctggagagctggaacttttctaactaaaactgaa
tgtgaagcatgcaattgtcatggaaaagctgaagaatgctattatgatgaaaatgttgcc
agaagaaatctgagtttgaatatacgtggaaagtacattggagggggtgtctgcattaat
tgtacccaaaacactgctggtataaactgcgagacatgtactgatggcttcttcagaccc
aaaggggtatctccaaattatccaaggccatgccagccatgtcattgcgatccaattggt
tccttaaatgaagtctgtgtcaaggatgagaaacatgctcgacgaggtttggcacctgga
tcctgtcattgcaaaactggttttggaggtgtgagctgtgatcggtgtgccaggggctac
actggctacccggactgcaaagcctgtaactgcagtgggttagggagcaaaaatgaggat
ccttgttttggcccctgtatctgcaaggaaaatgttgaaggaggagactgtagtcgttgc
aaatccggcttcttcaatttgcaagaggataattggaaaggctgcgatgagtgtttctgt
tcaggggtttcaaacagatgtcagagttcctactggacctatggcaaaatacaagatatg
agtggctggtatctgactgaccttcctggccgcattcgagtggctccccagcaggacgac
ttggactcacctcagcagatcagcatcagtaacgcggaggcccggcaagccctgccgcac
agctactactggagcgcgccggctccctatctgggaaacaaactcccagcagtaggagga
cagttgacatttaccatatcatatgaccttgaagaagaggaagaagatacagaacgtgtt
ctccagcttatgattatcttagagggtaatgacttgagcatcagcacagcccaagatgag
gtgtacctgcacccatctgaagaacatactaatgtattgttacttaaagaagaatcattt
accatacatggcacacattttccagtccgtagaaaggaatttatgacagtgcttgcgaat
ttgaagagagtcctcctacaaatcacatacagctttgggatggatgccatcttcaggttg
agctctgttaaccttgaatccgctgtctcctatcctactgatggaagcattgcagcagct
gtagaagtgtgtcagtgcccaccagggtatactggctcctcttgtgaatcttgttggcct
aggcacaggcgagttaacggcactatttttggtggcatctgtgagccatgtcagtgcttt
ggtcatgcggagtcctgtgatgacgtcactggagaatgcctgaactgtaaggatcacaca
ggtggcccatattgtgataaatgtcttcctggtttctatggcgagcctactaaaggaacc
tctgaagactgtcaaccctgtgcctgtccactcaatatcccatccaataactttagccca
acgtgccatttagaccggagtcttggattgatctgtgatggatgccctgtcgggtacaca
ggaccacgctgtgagaggtgtgcagaaggctattttggacaaccctctgtacctggagga
tcatgtcagccatgccaatgcaatgacaaccttgacttctccatccctggcagctgtgac
agcttgtctggctcctgtctgatatgtaaaccaggtacaacaggccggtactgtgagctc
tgtgctgatggatattttggagatgcagttgatgcgaagaactgtcagccctgtcgctgt
aatgccggtggctctttctctgaggtttgccacagtcaaactggacagtgtgagtgcaga
gccaacgttcagggtcagagatgtgacaaatgcaaggctgggacctttggcctacaatca
gcaaggggctgtgttccctgcaactgcaattcttttgggtctaagtcattcgactgtgaa
gagagtggacaatgttggtgccaacctggagtcacagggaagaaatgtgaccgctgtgcc
cacggctatttcaacttccaagaaggaggctgcacagcttgtgaatgttctcatctgggt
aataattgtgacccaaagactgggcgatgcatttgccctcccaataccattggagagaaa
tgttctaaatgtgcacccaatacctggggccacagcattaccactggttgtaaggcttgt
aactgcagcacagtgggatccttggatttccaatgcaatgtaaatacaggccaatgcaac
tgtcatccaaaattctctggtgcaaaatgtacagagtgcagtcgaggtcactggaactac
cctcgctgcaatctctgtgactgcttcctccctgggacagatgccacaacctgtgattca
gagactaaaaaatgctcctgtagtgatcaaactgggcagtgcacttgtaaggtgaatgtg
gaaggcatccactgtgacagatgccggcctggcaaattcggactcgatgccaagaatcca
cttggctgcagcagctgctattgcttcggcactactacccagtgctctgaagcaaaagga
ctgatccggacgtgggtgactctgaaggctgagcagaccattctacccctggtagatgag
gctctgcagcacacgaccaccaagggcattgtttttcaacatccagagattgttgcccac
atggacctgatgagagaagatctccatttggaacctttttattggaaacttccagaacaa
tttgaaggaaagaagttgatggcctatgggggcaaactcaagtatgcaatctatttcgag
gctcgggaagaaacaggtttctctacatataatcctcaagtgatcattcgaggtgggaca
cctactcatgctagaattatcgtcaggcatatggctgctcctctgattggccaattgaca
aggcatgaaattgaaatgacagagaaagaatggaaatattatggggatgatcctcgagtc
catagaactgtgacccgagaagacttcttggatatactatatgatattcattacattctt
atcaaagctacttatggaaatttcatgcgacaaagcaggatttctgaaatctcaatggag
gtagctgaacaaggacgtggaacaacaatgactcctccagctgacttgattgaaaaatgt
gattgtcccctgggctattctggcctgtcctgtgaggcatgcttgccgggattttatcga
ctgcgttctcaaccaggtggccgcacccctggaccaaccctgggcacctgtgttccatgt
caatgtaatggacacagcagcctgtgtgaccctgaaacatcgatatgccagaattgtcaa
catcacactgctggtgacttctgtgaacgatgtgctcttggatactatggaattgtcaag
ggattgccaaatgactgtcagcaatgtgcctgccctctgatttcttccagtaacaatttc
agcccctcttgtgtcgcagaaggacttgacgactaccgctgcacggcttgtccacgggga
tatgaaggccagtactgtgaaaggtgtgcccctggctatactggcagtccaggcaaccct
ggaggctcctgccaagaatgtgagtgtgatccctatggctcactgcctgtgccctgtgac
cctgtcacaggattctgcacgtgccgacctggagccacgggaaggaagtgtgacggctgc
aagcactggcatgcacgcgagggctgggagtgtgttttttgtggagatgagtgcactggc
cttcttctcggtgacttggctcgcctggagcagatggtcatgagcatcaacctcactggt
ccgctgcctgcgccatataaaatgctgtatggtcttgaaaatatgactcaggagctaaag
cacttgctgtcacctcagcgggccccagagaggcttattcagctggcagagggcaatctg
aatacactcgtgaccgaaatgaacgagctgctgaccagggctaccaaagtgacagcagat
ggcgagcagaccggacaggatgctgagaggaccaacacaagagcaaagtccctgggagaa
ttcattaaggagcttgcccgggatgcagaagctgtaaatgaaaaagctataaaactaaat
gaaactctaggaactcgagacgaggcctttgagagaaatttggaagggcttcagaaagag
attgaccagatgattaaagaactgaggaggaaaaatctagagacacaaaaggaaattgct
gaagatgagttggtagctgcagaagcccttctgaaaaaagtgaagaagctgtttggagag
tcccggggggaaaatgaagaaatggagaaggatctccgggaaaaactggctgactacaaa
aacaaagttgatgatgcttgggaccttttgagagaagccacagataaaatcagagaagct
aatcgcctatttgcagtaaatcagaaaaacatgactgcattggagaaaaagaaggaggct
gttgaaagcggcaaacgacaaattgagaacactttaaaagagggcaatgacatactcgat
gaagccaaccgtcttgcagatgaaatcaactccatcatagactatgttgaagacatccaa
actaaattgccacctatgtctgaggagcttaatgataaaatagatgacctctcccaagaa
ataaaggacaggaagcttgctgagaaggtgtcccaggctgagagccacgcagctcagttg
aatgactcatctgctgtccttgatggaatccttgatgaggctaaaaacatctccttcaat
gccactgcagccttcaaagcttacagcaatattaaggactatattgatgaagctgagaaa
gttgccaaagaagccaaagatcttgcacatgaagctacaaaactggcaacaggtcctcgg
ggtttattaaaggaagatgccaaaggctgtcttcagaaaagcttcaggattcttaacgaa
gccaagaagttagcaaatgatgtaaaagaaaatgaagaccatctaaatggcttaaaaacc
aggatagaaaatgctgatgctagaaatggggatctcttgagaactttgaatgacactttg
ggaaagttatcagctattccaaatgatacagctgctaaactgcaagctgttaaggacaaa
gccagacaagccaacgacacagctaaagatgtactggcacagattacagagctccaccag
aacctcgatggcctgaagaagaattacaataaactagcagacagcgtcgccaaaacgaat
gctgtggttaaagatccttccaagaacaaaatcattgccgatgcagatgccactgtcaaa
aatttagaacaggaagctgaccggctaatagataaactcaaacccatcaaggaacttgag
gataacctaaagaaaaacatctctgagataaaggaattgataaaccaagctcggaaacaa
gccaattctatcaaagtatctgtgtcttcaggaggtgactgcattcgaacatacaaacca
gaaatcaagaaaggaagttacaataatattgttgtcaacgtaaagacagctgttgctgat
aacctcctcttttatcttggaagtgccaaatttattgactttctggctatagaaatgcgt
aaaggcaaagtcagcttcctctgggatgttggatctggagttggacgtgtagagtaccca
gatttgactattgatgactcatattggtaccgtatcgtagcatcaagaactgggagaaat
ggaactatttctgtgagagccctggatggacccaaagccagcattgtgcccagcacacac
cattcgacgtctcctccagggtacacgattctagatgtggatgcaaatgcaatgctgttt
gttggtggcctgactgggaaattaaagaaggctgatgctgtacgtgtgattacattcact
ggctgcatgggagaaacatactttgacaacaaacctataggtttgtggaatttccgagaa
aaagaaggtgactgcaaaggatgcactgtcagtcctcaggtggaagatagtgaggggact
attcaatttgatggagaaggttatgcattggtcagccgtcccattcgctggtaccccaac
atctccactgtcatgttcaagttcagaacattttcttcgagtgctcttctgatgtatctt
gccacacgagacctgagagatttcatgagtgtggagctcactgatgggcacataaaagtc
agttacgatctgggctcaggaatggcttccgttgtcagcaatcaaaaccataatgatggg
aaatggaaatcattcactctgtcaagaattcaaaaacaagccaatatatcaattgtagat
atagatactaatcaggaggagaatatagcaacttcgtcttctggaaacaactttggtctt
gacttgaaagcagatgacaaaatatattttggtggcctgccaacgctgagaaacttgagt
atgaaagcaaggccagaagtaaatctgaagaaatattccggctgcctcaaagatattgaa
atttcaagaactccgtacaatatactcagtagtcccgattatgttggtgttaccaaagga
tgttccctggagaatgtttacacagttagctttcctaagcctggttttgtggagctctcc
cctgtgccaattgatgtaggaacagaaatcaacctgtcattcagcaccaagaatgagtcc
ggcatcattcttttgggaagtggagggacaccagcaccacctaggagaaaacgaaggcag
actggacaggcctattatgtaatactcctcaacaggggccgtctggaagtgcatctctcc
acaggggcacgaacaatgaggaaaattgtgatcagaccagagccgaatctgtttcatgat
ggaagagaacattccgttcatgtagagcgaactagaggcatctttacagttcaagtggat
gaaaacagaagatacatgcaaaacctgacagttgaacagcctatcgaagttaaaaagctt
ttcgttgggggtgctccacctgaatttcaaccttccccactcagaaatattcctcctttt
gaaggctgcatatggaatcttgttattaactctgtccccatggactttgcaaggcctgtg
tccttcaaaaatgctgacattggtcgctgtgcccatcagaaactccgtgaagatgaagat
ggagcagctccagctgaaatagttatccagcctgagccagttcccaccccagcctttcct
acgcccaccccagttctgacacatggtccttgtgctgcagaatcagaaccagctcttttg
atagggagcaagcagttcgggctttcaagaaacagtcacattgcaattgcatttgatgac
accaaagttaaaaaccgtctcacaattgagttggaagtaagaaccgaagctgaatccggc
ttgcttttttacatggctcgcatcaatcatgctgattttgcaacagttcagctgagaaat
ggattgccctacttcagctatgacttggggagtggggacacccacaccatgatccccacc
aaaatcaatgatggccagtggcacaagattaagataatgagaagtaagcaagaaggaatt
ctttatgtagatggggcttccaacagaaccatcagtcccaaaaaagccgacatcctggat
gtcgtgggaatgctgtatgttggtgggttacccatcaactacactacccgaagaattggt
ccagtgacctatagcattgatggctgcgtcaggaatctccacatggcagaggcccctgcc
gatctggaacaacccacctccagcttccatgttgggacatgttttgcaaatgctcagagg
ggaacatattttgacggaaccggttttgccaaagcagttggtggattcaaagtgggattg
gaccttcttgtagaatttgaattccgcacaactacaacgactggagttcttctggggatc
agtagtcaaaaaatggatggaatgggtattgaaatgattgatgaaaagttgatgtttcat
gtggacaatggtgcgggcagattcactgctgtctatgatgctggggttccagggcatttg
tgtgatggacaatggcataaagtcactgccaacaagatcaaacaccgcattgagctcaca
gtcgatgggaaccaggtggaagcccaaagcccaaacccagcatctacatcagctgacaca
aatgaccctgtgtttgttggaggcttcccagatgacctcaagcagtttggcctaacaacc
agtattccgttccgaggttgcatcagatccctgaagctcaccaaaggcacaggcaagcca
ctggaggttaattttgccaaggccctggaactgaggggcgttcaacctgtatcatgccca
gccaactaa

KEGG   Homo sapiens (human): 3909Help
Entry
3909              CDS       T01001                                 

Gene name
LAMA3, BM600, E170, LAMNA, LOCS
Definition
(RefSeq) laminin subunit alpha 3
  KO
K06240  laminin, alpha 3/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Disease
H00586  Epidermolysis bullosa, junctional
H00813  Laryngo onycho cutaneous syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3909 (LAMA3)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3909 (LAMA3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3909 (LAMA3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3909 (LAMA3)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    3909 (LAMA3)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3909 (LAMA3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    3909 (LAMA3)
   05145 Toxoplasmosis
    3909 (LAMA3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Laminin_EGF Laminin_I Laminin_G_2 Laminin_N Laminin_G_1 Laminin_II Laminin_B Laminin_G_3 Spc7
Motif
Other DBs
NCBI-GeneID: 3909
NCBI-ProteinID: NP_937762
OMIM: 600805
HGNC: 6483
Ensembl: ENSG00000053747
Vega: OTTHUMG00000131874
Pharos: Q16787(Tbio)
UniProt: Q16787
LinkDB All DBs
Position
18q11.2
AA seq 3333 aa AA seqDB search
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARI
WATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAI
DGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST
YSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGA
KNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCV
CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHG
HASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAP
DGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSS
EDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSA
LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ
CKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG
DSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENN
YYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKS
SGSLFRVILRYVNPGTEAVSGHITIYPSWGAAQSKEIIFLPSKEPAFVTVPGNGFADPFS
ITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLPVT
RFPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVV
EYSTEAAQLFVVDVNVKSSGSVLAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADI
QLKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALI
LDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGRVPHLGRYVFVIHFYQAAHPT
FPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLV
LVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYH
KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCE
EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRC
KPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE
GSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSN
SMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQL
TGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQG
LYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLY
TGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTN
SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHP
LTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQM
RHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN
NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMREL
RNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRA
RLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQL
MEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIK
RNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLS
SNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGD
IDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVN
KLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVE
VRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTC
VYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDM
DGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKT
FNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAEN
GDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQ
NTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGVTKKC
SEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTL
EDGYIELSTSDSGGPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISS
SRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKG
STRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFK
LPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALGTDGKKLRIKSK
EKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLP
TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEF
KLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQ
WHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFF
GCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ
NT seq 10002 nt NT seq  +upstreamnt  +downstreamnt
atggcggcggccgcgcggcctcggggtcgggcactggggccagtactgccgccgacgccg
ctgctcctgctggtactgcgggtgctgccagcctgcggggcgaccgctcgggatcccggg
gccgcggccgggctcagccttcacccgacttacttcaacctggccgaggcggcgaggatt
tgggccaccgccacctgcggggagaggggacccggcgaggggaggccccagcccgagctc
tactgcaagttggtcgggggccccaccgccccaggcagcggccacaccatccagggccag
ttctgtgactattgcaattctgaagaccccaggaaagcacatcctgtcaccaatgccatc
gatggatctgaacgttggtggcaaagccctcccctgtcctcaggcacacagtacaacaga
gtcaacctcaccttggatctggggcagctcttccatgtggcctatattttaatcaaattt
gcaaattctcctcgccctgatctttgggtcttggaaagatctgtagactttggaagcacc
tactcaccatggcaatattttgctcattctaaagtagactgtttaaaagaatttgggcgg
gaggcaaatatggctgtcacccgggatgatgatgtactttgtgttactgaatattcccgt
attgtacctttggaaaatggtgaggttgtggtgtccttgataaacggtcgtccaggtgca
aaaaattttactttctctcacaccctgagggagtttaccaaggcaacaaacatccgcttg
cgttttcttagaaccaatacgcttcttggacacctcatctccaaagcccagcgagatcca
actgtcactcggcggtattattacagcataaaggacatcagcattggtgggcagtgtgtt
tgcaatggccatgctgaagtgtgcaatataaacaatcctgaaaaactgtttcggtgtgaa
tgccagcaccacacctgtggggagacgtgtgatcgctgctgcacagggtacaatcagagg
cgctggcggcccgccgcttgggagcagagccacgagtgtgaagcatgcaactgccacggc
catgccagcaactgttactatgatccagatgttgagcggcagcaggcaagcttgaatacc
cagggcatctatgctggtggaggggtctgcattaactgtcagcacaacacagctggagta
aactgtgaacagtgtgctaagggctattaccgcccttatggggttccagtggatgcccct
gatggctgcatcccctgcagctgtgaccctgagcatgcggatggctgtgaacagggttca
ggccgctgtcactgcaagccaaatttccacggagacaactgtgagaagtgtgcaattgga
tactacaatttcccattttgcttgagaattcccatttttcctgtttctacaccaagttca
gaagatccagtagctggagatataaaagggtgtgactgtaatctggaaggtgttctccct
gaaatatgtgatgcccacggacggtgcctgtgccgccctggggttgagggccctcgatgt
gatacctgccgctctggtttctactcattccctatttgccaagcctgctggtgttcagcc
cttggatcctaccagatgccctgcagctcagtgactggacagtgtgaatgtcggccagga
gttacaggacagcggtgtgacaggtgtctctcaggagcttatgatttcccccactgccaa
ggttccagcagtgcttgtgacccagctggtaccatcaactccaatttggggtattgccaa
tgcaagcttcatgttgaaggtcctacttgtagccgctgcaaactgttatattggaatctg
gacaaagaaaaccccagtggatgttcagaatgcaagtgccataaggcgggaacagtgagt
ggaactggagagtgtaggcagggagatggtgactgtcactgcaagtcccatgtgggtggc
gattcctgcgacacctgtgaagatggatattttgctttggaaaagagcaattactttggg
tgtcaagggtgtcagtgtgacattggtggggcattgtcctccatgtgcagtgggccctcg
ggagtgtgccagtgccgagagcatgtcgtgggaaaggtgtgccagcggcctgaaaacaac
tactatttcccagatttgcatcatatgaagtatgagattgaagacggcagcacacctaat
gggagagaccttcgatttggatttgatccgctggcatttcctgagtttagctggagagga
tatgcccaaatgacctcagtacagaatgatgtaagaataacattgaatgtagggaagtca
agtggctccttgtttcgtgttattctgagatacgttaaccctggaactgaagcagtatct
ggccatataactatttatccatcctggggtgctgctcaaagcaaagagatcatcttcctg
ccgagtaaggagccagcctttgtcactgtccctggaaatggttttgcagacccattttca
atcacaccaggaatatgggttgcttgtattaaggcagaaggagtccttctggattacctg
gtgctgctccccagggactactatgaagcctctgtactgcagctgccagtcacagaacca
tgtgcctacgcaggacctccccaagaaaattgcttactctaccagcatttgccagtgacc
agattcccctgtaccctggcttgtgaggccagacacttcctgcttgatggggagccaaga
cccgtggcagtgaggcagcccacacctgcacaccctgtcatggtggacctcagcgggaga
gaggtggaattgcatctgcggctgcgcatcccacaggttggccactacgtggttgtggtc
gagtattccacggaggcagctcagctgtttgtggttgatgtgaatgtgaagagctccggg
tctgttctggcaggccaggtgaacatttacagctgcaactacagtgttctctgccggagt
gctgtgattgatcacatgagccgcatcgccatgtatgagctattggcagatgcagacatt
cagctcaagggacacatggcccgattccttctgcatcaagtttgtatcatacctattgaa
gaattctcagctgagtatgtgagaccacaagtccactgcattgccagttatgggcgattt
gtcaatcaaagtgccacctgtgtctccttggcccatgaaactcctccaacagcattaatt
ttggatgttctaagtggcaggcctttccctcacctgccccagcagtcgtcaccttctgtt
gatgttcttcctggggtcaccttgaaggcaccgcagaatcaagtgaccctgagaggacgt
gtaccacacctgggccgatacgtctttgtcatccatttttaccaagcagcgcacccgacg
tttcccgcgcaggtgtcggtggatggcgggtggccacgggcaggctccttccatgcctct
ttttgcccccatgtgcttggctgccgggatcaagtgattgccgaaggccagattgagttt
gacatctcagagcctgaagtggccgcaactgtgaaggttccagaaggaaagtccttggtt
ttggtccgtgttctagtggtgcctgcagaaaactatgactaccaaatacttcacaaaaaa
tccatggacaagtcactcgagtttatcaccaattgtggaaaaaacagcttttaccttgac
ccccagacagcctccagattctgtaagaattccgccaggtccctggtggccttttaccac
aagggcgccctgccttgtgagtgccaccccactggggccaccggccctcactgcagccct
gagggtgggcagtgcccatgccagcccaacgtcatcgggcggcagtgcacccgctgtgca
acaggccactacggattcccacgctgcaagccgtgcagctgtggtcggcgcctttgtgaa
gagatgacggggcagtgccgctgccctccccgcacggtcaggccccagtgtgaggtgtgt
gagacacactcattcagcttccaccccatggccggctgcgaaggctgcaactgttccagg
aggggcaccatcgaggctgccatgccggagtgtgaccgggacagcgggcagtgcagatgc
aagcccagaatcacagggcggcagtgtgaccgatgtgcttccgggttttaccgctttcct
gagtgtgttccctgcaattgcaacagagatgggactgagccaggagtgtgtgacccaggg
accggggcttgcctctgcaaggaaaatgtagaaggcacagagtgtaatgtgtgtcgagaa
ggctcattccatttggacccagccaatctcaagggttgtaccagctgtttctgttttgga
gtaaataatcaatgtcacagctcacataagcgaaggactaagtttgtggatatgctgggc
tggcacctggagacagcagacagagtggacatccctgtctctttcaacccaggcagcaac
agtatggtggcggatctccaggagctgcccgcaaccatccacagcgcgtcctgggtcgca
cccacctcctacctgggggacaaggtttcttcatatggtggttacctcacttaccaagcc
aagtcctttggcttgcctggcgacatggttcttctggaaaagaagccggatgtacagctc
actggtcagcacatgtccatcatctatgaggagacaaacaccccacggccagaccggctg
catcatggacgagtgcacgtggtcgagggaaacttcagacatgccagcagccgtgcccca
gtgtctagggaggagctgatgacagtgctgtctagactggcagatgtgcgcatccaaggc
ctctacttcacagagactcaaaggctcaccctgagcgaggtggggctagaggaagcctct
gacacaggaagtgggcgcatagcacttgctgtggaaatctgtgcctgcccccctgcctac
gctggtgactcttgtcagggttgtagccctggatactatcgggatcataaaggcttgtat
accggacggtgtgttccctgcaattgcaacggacattcaaatcaatgccaggatggctca
ggcatatgtgttaactgtcagcacaacaccgcgggagagcactgtgaacgctgccaggag
ggctactatggcaacgccgtccacggatcctgcagggcctgcccatgtcctcacactaac
agctttgccactggctgtgtggtgaatgggggagacgtgcggtgctcctgcaaagctggg
tacacaggaacacagtgtgaaaggtgtgcaccgggatatttcgggaatccccagaaattc
ggaggtagctgccaaccatgcagttgtaacagcaatggccagctgggcagctgtcatccc
ctgactggagactgcataaaccaagaacccaaagatagcagccctgcagaagaatgtgat
gattgcgacagctgtgtgatgaccctcctgaacgacctggccaccatgggcgagcagctc
cgcctggtcaagtctcagctgcagggcctgagtgccagcgcagggcttctggagcagatg
aggcacatggagacccaggccaaggacctgaggaatcagttgctcaactaccgttctgcc
atttcaaatcatggatcaaaaatagaaggcctggaaagagaactgactgatttgaatcaa
gaatttgagactttgcaagaaaaggctcaagtaaattccagaaaagcacaaacattaaac
aacaatgttaatcgggcaacacaaagcgcaaaagaactggatgtgaagattaaaaatgtc
atccggaatgtgcacattcttttaaagcagatctctgggacagatggagagggaaacaac
gtgccttcaggtgacttttccagagagtgggctgaagcccagcgcatgatgagggaactg
cggaacaggaactttggaaagcacctcagagaagcagaagctgataaaagggagtcgcag
ctcttgctgaaccggataaggacctggcagaaaacccaccagggggagaacaatgggctt
gctaacagtatccgggattctttaaatgaatacgaagccaaactcagtgaccttcgtgct
cggctgcaggaggcagctgcccaagccaagcaggcaaatggcttgaaccaagaaaacgag
agagctttgggagccattcagagacaagtgaaagaaataaattccctgcagagtgatttc
accaagtatctaaccactgcagactcatctttgttgcaaaccaacattgcgctgcagctg
atggagaaaagccagaaggaatatgaaaaattagctgccagtttaaatgaagcaagacaa
gaactaagtgacaaagtaagagaactttccagatctgctggcaaaacatcccttgtggag
gaggcagaaaagcacgcgcggtccttacaagagctggcaaagcagctggaagagatcaag
agaaacgccagcggggatgagctggtgcgctgtgctgtggatgccgccaccgcctacgag
aacatcctcaatgccatcaaagcggccgaggacgcagccaacagggctgccagtgcatct
gaatctgccctccagacagtgataaaggaagatctgccaagaaaagctaaaaccctgagt
tccaacagtgataaactgttaaatgaagccaagatgacacaaaagaagctaaagcaagaa
gtcagtccagctctcaacaacctacagcaaaccctgaatattgtgacagttcagaaagaa
gtgatagacaccaatctcacaactctccgagatggtcttcatgggatacagagaggtgat
attgatgctatgatcagtagtgcaaagagcatggtcagaaaggccaacgacatcacagat
gaggttctggatgggctcaaccccatccagacagatgtggaaagaattaaggacacctat
gggaggacacagaacgaagacttcaaaaaggctctgactgatgcagataactcggtgaat
aagttaaccaacaaactacctgatctttggcgcaagattgaaagtatcaaccaacagctg
ttgcccttgggaaacatctctgacaacatggacagaatacgagaactaattcagcaggcc
agagatgctgccagtaaggttgctgtccccatgaggttcaatggtaaatctggagtcgaa
gtccgactgccaaatgacctggaagatttgaaaggatatacatctctgtccttgtttctc
caaaggcccaactcaagagaaaatgggggtactgagaatatgtttgtgatgtaccttgga
aataaagatgcctcccgggactacatcggcatggcagttgtggatggccagctcacctgt
gtctacaacctgggggaccgtgaggctgaactccaagtggaccagatcttgaccaagagt
gagactaaggaggcagttatggatcgggtgaaatttcagagaatttatcagtttgcaagg
cttaattacaccaaaggagccacatccagtaaaccagaaacacccggagtctatgacatg
gatggtagaaatagcaatacactccttaatttggatcctgaaaatgttgtattttatgtt
ggaggttacccacctgattttaaacttcccagtcgactaagtttccctccatacaaaggt
tgtattgaattagatgacctcaatgaaaatgttctgagcttgtacaacttcaaaaaaaca
ttcaatctcaacacaactgaagtggagccttgtagaaggaggaaggaagagtcagacaaa
aattattttgaaggtacgggctatgctcgagttccaactcaaccacatgctcccatccca
acctttggacagacaattcagaccaccgtggatagaggcttgctgttctttgcagaaaac
ggggatcgcttcatatctctaaatatagaagatggcaagctcatggtgagatacaaactg
aattcagagctaccaaaagagagaggagttggagacgccataaacaacggcagagaccat
tcgattcagatcaaaattggaaaactccaaaagcgtatgtggataaatgtggacgttcaa
aacactataattgatggtgaagtatttgatttcagcacatattatctgggaggaattcca
attgcaatcagggaaagatttaacatttctacgcctgctttccgaggctgcatgaaaaat
ttgaagaaaaccagtggtgtcgttagattgaatgatactgtgggagtaaccaaaaagtgc
tcggaagactggaagcttgtgcgatctgcctcattctccagaggaggacaattgagtttc
actgatttgggcttaccacctactgaccacctccaggcctcatttggatttcagaccttt
caacccagtggcatattattagatcatcagacatggacaaggaacctgcaggtcactctg
gaagatggttacattgaattgagcaccagcgatagcggcggcccaatttttaaatctcca
cagacgtatatggatggtttactgcattatgtatctgtaataagcgacaactctggacta
cggcttctcatcgatgaccagcttctgagaaatagcaaaaggctaaaacacatttcaagt
tcccggcagtctctgcgtctgggcgggagcaattttgagggttgtattagcaatgttttt
gtccagaggttatcactgagtcctgaagtcctagatttgaccagtaactctctcaagaga
gatgtgtccctgggaggctgcagtttaaacaaaccaccttttctaatgttgcttaaaggt
tctaccaggtttaacaagaccaagacttttcgtatcaaccagctgttgcaggacacacca
gtggcctccccaaggagcgtgaaggtgtggcaagatgcttgctcaccacttcccaagacc
caggccaatcatggagccctccagtttggggacattcccaccagccacttgctattcaag
cttcctcaggagctgctgaaacccaggtcacagtttgctgtggacatgcagacaacatcc
tccagaggactggtgtttcacacgggcactaagaactcctttatggctctttatctttca
aaaggacgtctggtctttgcactggggacagatgggaaaaaattgaggatcaaaagcaag
gagaaatgcaatgatgggaaatggcacacggtggtgtttggccatgatggggaaaagggg
cgcttggttgtggatggactgagggcccgggagggaagtttgcctggaaactccaccatc
agcatcagagcgccagtttacctgggatcacctccatcagggaaaccaaagagcctcccc
acaaacagctttgtgggatgcctgaagaactttcagctggattcaaaacccttgtatacc
ccttcttcaagcttcggggtgtcttcctgcttgggtggtcctttggagaaaggcatttat
ttctctgaagaaggaggtcatgtcgtcttggctcactctgtattgttggggccagaattt
aagcttgttttcagcatccgcccaagaagtctcactgggatcctaatacacatcggaagt
cagcccgggaagcacttatgtgtttacctggaggcaggaaaggtcacggcctctatggac
agtggggcaggtgggacctcaacgtcggtcacaccaaagcagtctctgtgtgatggacag
tggcactcggtggcagtcaccataaaacaacacatcctgcacctggaactggacacagac
agtagctacacagctggacagatccccttcccacctgccagcactcaagagccactacac
cttggaggtgctccagccaatttgacgacactgaggatccctgtgtggaaatcattcttt
ggctgtctgaggaatattcatgtcaatcacatccctgtccctgtcactgaagccttggaa
gtccaggggcctgtcagtctgaatggttgtcctgaccagtaa

KEGG   Homo sapiens (human): 3910Help
Entry
3910              CDS       T01001                                 

Gene name
LAMA4, CMD1JJ, LAMA3, LAMA4*-1
Definition
(RefSeq) laminin subunit alpha 4
  KO
K06241  laminin, alpha 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05143  African trypanosomiasis
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3910 (LAMA4)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3910 (LAMA4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3910 (LAMA4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3910 (LAMA4)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    3910 (LAMA4)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3910 (LAMA4)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    3910 (LAMA4)
   05145 Toxoplasmosis
    3910 (LAMA4)
   05143 African trypanosomiasis
    3910 (LAMA4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Laminin_G_2 Laminin_I Laminin_G_1 Laminin_II Laminin_EGF Laminin_G_3 Focal_AT
Motif
Other DBs
NCBI-GeneID: 3910
NCBI-ProteinID: NP_001098676
OMIM: 600133
HGNC: 6484
Ensembl: ENSG00000112769
Vega: OTTHUMG00000015386
Pharos: Q16363(Tbio)
UniProt: Q16363 A0A0A0MQS9
LinkDB All DBs
Position
6q21
AA seq 1823 aa AA seqDB search
MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGKSGVLS
VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
HPVSFSKAALVSGAVSINSCPAA
NT seq 5472 nt NT seq  +upstreamnt  +downstreamnt
atggctttgagctcagcctggcgctcggttctgcctctgtggctcctctggagcgctgcc
tgctcccgcgccgcgtccggggacgacaacgcttttccttttgacattgaagggagctca
gcggttggcaggcaagacccgcctgagacgagcgaaccccgcgtggctctgggacgcctg
ccgcctgcggccgagaaatgcaatgctggattctttcacaccctgtcgggagaatgtgtg
ccctgcgactgtaatggcaattccaacgagtgtttggacggctcaggatactgtgtgcac
tgccagcggaacacaacaggagagcactgtgaaaagtgtctggatggttatatcggagat
tccatcaggggagcaccccaattctgccagccgtgcccctgtcccctgccccacttggcc
aattttgcagaatcctgctataggaaaaatggagctgttcggtgcatttgtaacgaaaat
tatgctggacctaactgtgaaagatgtgctcccggttactatggaaaccccttactcatt
ggaagcacctgtaagaaatgtgactgcagtggaaattcagatcccaacctgatctttgaa
gattgtgatgaagtcactggccagtgtaggaattgcttacgcaacaccaccggattcaag
tgtgaacgttgcgctcctggctactatggggacgccaggatagccaagaactgtgcagtg
tgcaactgcgggggaggcccatgtgacagtgtaaccggagaatgcttggaagaaggtttt
gaaccccctacaggcatggactgcccaaccataagctgtgataagtgcgtctgggacctg
actgatgacctgcggttagcagcgctctccatcgaggaaggcaaatccggggtgctgagc
gtatcctctggggccgccgctcataggcacgtgaatgaaatcaacgccaccatctacctc
ctcaaaacaaaattgtcagaaagagaaaaccaatacgccctaagaaagatacaaatcaac
aatgctgagaacacgatgaaaagccttctgtctgacgtagaggaattagttgaaaaggaa
aatcaagcctccagaaaaggacaacttgttcagaaggaaagcatggacaccattaaccac
gcaagtcagctggtagagcaagcccatgatatgagggataaaatccaagagatcaacaac
aagatgctctattatggggaagagcatgaacttagccccaaggaaatctctgagaagctg
gtgttggcccagaagatgcttgaagagattagaagccgtcaaccatttttcacccaacgg
gagctcgtggatgaggaggcagatgaggcttacgaactactgagccaggctgagagctgg
cagcggctgcacaatgagacccgcactctgtttcctgtcgtcctggagcagctggatgac
tacaatgctaagttgtcagatctccaggaagcacttgaccaggcccttaactatgtcagg
gatgccgaagacatgaacagggccacagcagccaggcagcgggaccatgagaaacaacag
gaaagagtgagggaacaaatggaagtggtgaacatgtctctgagcacatctgcggactct
ctgacaacacctcgtctaactctttcagaacttgatgatataataaagaatgcgtcaggg
atttatgcagaaatagatggagccaaaagtgaactacaagtaaaactatctaacctaagt
aacctcagccatgatttagtccaagaagctattgaccatgcacaggaccttcaacaagaa
gctaatgaattgagcaggaagttgcacagttcagatatgaacgggctggtacagaaggct
ttggatgcatcaaatgtctatgaaaatattgttaattatgttagtgaagccaatgaaaca
gcagaatttgctttgaacaccactgaccgaatttatgatgcggtgagtgggattgatact
caaatcatttaccataaagatgaaagtgagaacctcctcaatcaagccagagaactgcaa
gcaaaggcagagtctagcagtgatgaagcagtggctgacactagcaggcgtgtgggtgga
gccctagcaaggaaaagtgcccttaaaaccagactcagtgatgccgttaagcaactacaa
gcagcagagagaggggatgcccagcagcgcctggggcagtctagactgatcaccgaggaa
gccaacaggacgacgatggaggtgcagcaggccactgcccccatggccaacaatctaacc
aactggtcacagaatcttcaacattttgactcttctgcttacaacactgcagtgaactct
gctagggatgcagtaagaaatctgaccgaggttgtccctcagctcctggatcagcttcgt
acggttgagcagaagcgacctgcaagcaacgtttctgccagcatccagaggatccgagag
ctcattgctcagaccagaagtgttgccagcaagatccaagtctccatgatgtttgatggc
cagtcagctgtggaagtgcactcgagaaccagtatggatgacttaaaggccttcacgtct
ctgagcctgtacatgaaaccccctgtgaagcggccggaactgaccgagactgcagatcag
tttatcctgtacctcggaagcaaaaacgccaaaaaagagtatatgggtcttgcaatcaaa
aatgataatctggtatacgtctataatttgggaactaaagatgtggagattcccctggac
tccaagcccgtcagttcctggcctgcttacttcagcattgtcaagattgaaagggtggga
aaacatggaaaggtgtttttaacagtcccgagtctaagtagcacagcagaggaaaagttc
attaaaaagggggaattttcgggagatgactctctgctggacctggaccctgaggacaca
gtgttttatgttggtggagtgccttccaacttcaagctccctaccagcttaaacctgcct
ggctttgttggctgcctggaactggccactttgaataatgatgtgatcagcttgtacaac
tttaagcacatctataatatggacccctccacatcagtgccatgtgcccgagataagctg
gccttcactcagagtcgggctgccagttacttcttcgatggctccggttatgccgtggtg
agagacatcacaaggagagggaaatttggtcaggtgactcgctttgacatagaagttcga
acaccagctgacaacggccttattctcctgatggtcaatggaagtatgtttttcagactg
gaaatgcgcaatggttacctacatgtgttctatgattttggattcagcggtggccctgtg
catcttgaagatacgttaaagaaagctcaaattaatgatgcaaaataccatgagatctca
atcatttaccacaatgataagaaaatgatcttggtagttgacagaaggcatgtcaagagc
atggataatgaaaagatgaaaataccttttacagatatatacattggaggagctcctcca
gaaatcttacaatccagggccctcagagcacaccttcccctagatatcaacttcagagga
tgcatgaagggcttccagttccaaaagaaggacttcaatttactggagcagacagaaacc
ctgggagttggttatggatgcccagaagactcacttatatctcgcagagcatatttcaat
ggacagagcttcattgcttcaattcagaaaatatctttctttgatggctttgaaggaggt
tttaatttccgaacattacaaccaaatgggttactattctattatgcttcagggtcagac
gtgttctccatctcactggataatggtactgtcatcatggatgtaaagggaatcaaagtt
cagtcagtagataagcagtacaatgatgggctgtcccacttcgtcattagctctgtctca
cccacaagatatgaactgatagtagataaaagcagagttgggagtaagaatcctaccaaa
gggaaaatagaacagacacaagcaagtgaaaagaagttttacttcggtggctcaccaatc
agtgctcagtatgctaatttcactggctgcataagtaatgcctactttaccagggtggat
agagatgtggaggttgaagatttccaacggtatactgaaaaggtccacacttctctttat
gagtgtcccattgagtcttcaccattgtttctcctccataaaaaaggaaaaaatttatcc
aagcctaaagcaagtcagaataaaaagggagggaaaagtaaagatgcaccttcatgggat
cctgttgctctgaaactcccagagcggaatactccaagaaactctcattgccacctttcc
aacagccctagagcaatagagcacgcctatcaatatggaggaacagccaacagccgccaa
gagtttgaacacttaaaaggagattttggtgccaaatctcagttttccattcgtctgaga
actcgttcctcccatggcatgatcttctatgtctcagatcaagaagagaatgacttcatg
actctatttttggcccatggccgcttggtttacatgtttaatgttggtcacaaaaaactg
aagattagaagccaggagaaatacaatgatggcctgtggcatgatgtgatatttattcga
gaaaggagcagtggccgactggtaattgatggtctccgagtcctagaagaaagtcttcct
cctactgaagctacctggaaaatcaagggtcccatttatttgggaggtgtggctcctgga
aaggctgtgaaaaatgttcagattaactccatctacagttttagtggctgtctcagcaat
ctccagctcaatggggcctccatcacctctgcttctcagacattcagtgtgaccccttgc
tttgaaggccccatggaaacaggaacttacttttcaacagaaggaggatacgtggttcta
gatgaatctttcaatattggattgaagtttgaaattgcatttgaagtccgtcccagaagc
agttccggaaccctggtccacggccacagtgtcaatggggagtacctaaatgttcacatg
aaaaatggacaggtcatagtgaaagtcaataatggcatcagagatttttccacctcagtt
acacccaagcagagtctctgtgatggcagatggcacagaattacagttattagagattct
aatgtggttcagttggatgtggactctgaagtgaaccatgtggttggacccctgaatcca
aaaccaattgatcacagggagcctgtgtttgttggaggtgttccagaatctctactgaca
ccacgcttggcccccagcaaacccttcacaggctgcatacgccactttgtgattgatgga
cacccagtgagcttcagtaaagcagccctggtcagcggcgccgtaagcatcaactcctgt
ccagcagcctga

KEGG   Homo sapiens (human): 3911Help
Entry
3911              CDS       T01001                                 

Gene name
LAMA5
Definition
(RefSeq) laminin subunit alpha 5
  KO
K06240  laminin, alpha 3/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3911 (LAMA5)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3911 (LAMA5)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3911 (LAMA5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3911 (LAMA5)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    3911 (LAMA5)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3911 (LAMA5)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    3911 (LAMA5)
   05145 Toxoplasmosis
    3911 (LAMA5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Laminin_EGF Laminin_I Laminin_N Laminin_G_2 Laminin_G_1 Laminin_II Laminin_B Laminin_G_3
Motif
Other DBs
NCBI-GeneID: 3911
NCBI-ProteinID: NP_005551
OMIM: 601033
HGNC: 6485
Ensembl: ENSG00000130702
Vega: OTTHUMG00000032908
Pharos: O15230(Tbio)
UniProt: O15230
LinkDB All DBs
Structure
PDB: 

Position
20q13.33
AA seq 3695 aa AA seqDB search
MAKRLCAGSALCVRGPRGPAPLLLVGLALLGAARAREEAGGGFSLHPPYFNLAEGARIAA
SATCGEEAPARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASNA
IDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGR
TYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPG
AMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRC
VCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCN
CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPL
DSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSND
TREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQP
CQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCD
EAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTA
CQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYC
EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDL
RGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQS
CEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRLELEEAATPEGHAVRFGFNPLEFEN
FSWRGYAQMAPVQPRIVARLNLTSPDLFWLVFRYVNRGAMSVSGRVSVREEGRSATCANC
TAQSQPVAFPPSTEPAFITVPQRGFGEPFVLNPGTWALRVEAEGVLLDYVVLLPSAYYEA
ALLQLRVTEACTYRPSAQQSGDNCLLYTHLPLDGFPSAAGLEALCRQDNSLPRPCPTEQL
SPSHPPLITCTGSDVDVQLQVAVPQPGRYALVVEYANEDARQEVGVAVHTPQRAPQQGLL
SLHPCLYSTLCRGTARDTQDHLAVFHLDSEASVRLTAEQARFFLHGVTLVPIEEFSPEFV
EPRVSCISSHGAFGPNSAACLPSRFPKPPQPIILRDCQVIPLPPGLPLTHAQDLTPAMSP
AGPRPRPPTAVDPDAEPTLLREPQATVVFTTHVPTLGRYAFLLHGYQPAHPTFPVEVLIN
AGRVWQGHANASFCPHGYGCRTLVVCEGQALLDVTHSELTVTVRVPKGRWLWLDYVLVVP
ENVYSFGYLREEPLDKSYDFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGC
HEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCIC
PPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRR
CDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAA
NPKGCTRCFCFGATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQPGTEMLRADLRH
VPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQGN
QMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLEQLQIRALFS
QISSAVFLRRVALEVASPAGQGALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGR
CVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVP
SNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLL
FSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHC
LCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCR
ECAPGYWGLPEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGH
SIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLR
SPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLA
AIRAVDRTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEA
ELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQE
LNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAAS
LDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIE
ASNAYSRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAMLQEQ
QRLGLVWAALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQ
DTATRVQSQLQAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSIL
ENRGVHNASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYT
ALKFYLQGPEPEPGQGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSI
DEDIGEQFAAVSLDRTLQFGHMSVTVERQMIQETKGDTVAPGAEGLLNLRPDDFVFYVGG
YPSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWL
TDGSYLDGTGFARISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVL
LYDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLELA
DAYYLGGVPPDQLPPSLRRLFPTGGSVRGCVKGIKALGKYVDLKRLNTTGVSAGCTADLL
VGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSLQQGR
VSLQLLRTEVKTQAGFADGAPHYVAFYSNATGVWLYVDDQLQQMKPHRGPPPELQPQPEG
PPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVSTGCAPALQAQT
PGLGPRGLQATARKASRRSRQPARHPACMLPPHLRTTRDSYQFGGSLSSHLEFVGILARH
RNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFLSNGHFVAQMEGLGTRLRAQSRQRS
RPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHTLFVGGLPASSHSSK
LPVTVGFSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATL
PDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFSTSVTRPSVL
CDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAPAPLYLGGLPEPMAVQPWPPA
YCGCMRRLAVNRSPVAMTRSVEVHGAVGASGCPAA
NT seq 11088 nt NT seq  +upstreamnt  +downstreamnt
atggcgaagcggctctgcgcggggagcgcactgtgtgttcgcggcccccggggccccgcg
ccgctgctgctggtcgggctggcgctgctgggcgcggcgcgggcgcgggaggaggcgggc
ggcggcttcagcctgcacccgccctacttcaacctggccgagggcgcccgcatcgccgcc
tccgcgacctgcggagaggaggccccggcgcgcggctccccgcgccccaccgaggacctt
tactgcaagctggtagggggccccgtggccggcggcgaccccaaccagaccatccggggc
cagtactgtgacatctgcacggctgccaacagcaacaaggcacaccccgcgagcaatgcc
atcgatggcacggagcgctggtggcagagtccaccgctgtcccgcggcctggagtacaac
gaggtcaacgtcaccctggacctgggccaggtcttccacgtggcctacgtcctcatcaag
tttgccaactcaccccggccggacctctgggtgctggagcggtccatggacttcggccgc
acctaccagccctggcagttctttgcctcctccaagagggactgtctggagcggttcggg
ccacagacgctggagcgcatcacacgggacgacgcggccatctgcaccaccgagtactca
cgcatcgtgcccctggagaacggagagatcgtggtgtccctggtgaacggacgtccgggc
gccatgaatttctcctactcgccgctgctacgtgagttcaccaaggccaccaacgtccgc
ctgcgcttcctgcgtaccaacacgctgctgggccatctcatggggaaggcgctgcgggac
cccacggtcacccgccggtattattacagcatcaaggatatcagcatcggaggccgctgt
gtctgccacggccacgcggatgcctgcgatgccaaagaccccacggacccgttcaggctg
cagtgcacctgccagcacaacacctgcgggggcacctgcgaccgctgctgccccggcttc
aatcagcagccgtggaagcctgcgactgccaacagtgccaacgagtgccagtcctgtaac
tgctacggccatgccaccgactgttactacgaccctgaggtggaccggcgccgcgccagc
cagagcctggatggcacctatcagggtgggggtgtctgtatcgactgccagcaccacacc
accggcgtcaactgtgagcgctgcctgcccggcttctaccgctctcccaaccaccctctc
gactcgccccacgtctgccgccgctgcaactgcgagtccgacttcacggatggcacctgc
gaggacctgacgggtcgatgctactgccggcccaacttctctggggagcggtgtgacgtg
tgtgccgagggcttcacgggcttcccaagctgctacccgacgccctcgtcctccaatgac
accagggagcaggtgctgccagccggccagattgtgaattgtgactgcagcgcggcaggg
acccagggcaacgcctgccggaaggacccaagggtgggacgctgtctgtgcaaacccaac
ttccaaggcacccattgtgagctctgcgcgccagggttctacggccccggctgccagccc
tgccagtgttccagccctggagtggccgatgaccgctgtgaccctgacacaggccagtgc
aggtgccgagtgggcttcgagggggccacatgtgatcgctgtgcccccggctactttcac
ttccctctctgccagttgtgtggctgcagccctgcaggaaccttgcccgagggctgcgat
gaggccggccgctgcctatgccagcctgagtttgctggacctcattgtgaccggtgccgc
cctggctaccatggtttccccaactgccaagcatgcacctgcgaccctcggggagccctg
gaccagctctgtggggcgggaggtttgtgccgctgccgccccggctacacaggcactgcc
tgccaggaatgcagccccggctttcacggcttccccagctgtgtcccctgccactgctct
gctgaaggctccctgcacgcagcctgtgacccccggagtgggcagtgcagctgccggccc
cgtgtgacggggctgcggtgtgacacatgtgtgcccggtgcctacaacttcccctactgc
gaagctggctcttgccaccctgccggtctggccccagtggatcctgcccttcctgaggca
caggttccctgtatgtgccgggctcacgtggaggggccgagctgtgaccgctgcaaacct
gggttctggggactgagccccagcaaccccgagggctgtacccgctgcagctgcgacctc
aggggcacactgggtggagttgctgagtgccagccgggcaccggccagtgcttctgcaag
ccccacgtgtgcggccaggcctgcgcgtcctgcaaggatggcttctttggactggatcag
gctgactattttggctgccgcagctgccggtgtgacattggcggtgcactgggccagagc
tgtgaaccgaggacgggcgtctgccggtgccgccccaacacccagggccccacctgcagc
gagcctgcgagggaccactacctcccggacctgcaccacctgcgcctggagctggaggag
gctgccacacctgagggtcacgccgtgcgctttggcttcaaccccctcgagttcgagaac
ttcagctggaggggctacgcgcagatggcacctgtccagcccaggatcgtggccaggctg
aacctgacctcccctgaccttttctggctcgtcttccgatacgtcaaccggggggccatg
agtgtgagcgggcgggtctctgtgcgagaggagggcaggtcggccacctgcgccaactgc
acagcacagagtcagcccgtggccttcccacccagcacggagcctgccttcatcaccgtg
ccccagaggggcttcggagagccctttgtgctgaaccctggcacctgggccctgcgtgtg
gaggccgaaggggtgctcctggactacgtggttctgctgcctagcgcatactacgaggcg
gcgctcctgcagctgcgggtgactgaggcctgcacataccgtccctctgcccagcagtct
ggcgacaactgcctcctctacacacacctccccctggatggcttcccctcggccgccggg
ctggaggccctgtgtcgccaggacaacagcctgccccggccctgccccacggagcagctc
agcccgtcgcacccgccactgatcacctgcacgggcagtgatgtggacgtccagcttcaa
gtggcagtgccacagccaggccgctatgccctagtggtggagtacgccaatgaggatgcc
cgccaggaggtgggcgtggccgtgcacaccccacagcgggccccccagcaggggctgctc
tccctgcacccctgcctgtacagcaccctgtgccggggcactgcccgggatacccaggac
cacctggctgtcttccacctggactcggaggccagcgtgaggctcacagccgaacaggca
cgcttcttcctgcacggggtcactctggtgcccattgaggagttcagcccggagttcgtg
gagccccgggtcagctgcatcagcagccacggcgcctttggccccaacagtgccgcctgt
ctgccctcgcgcttcccaaagccgccccagcccatcatcctcagggactgccaggtgatc
ccgctgccgcccggcctcccgctgacccacgcgcaggatctcactccagccatgtcccca
gctggaccccgacctcggccccccaccgctgtggaccctgatgcagagcccaccctgctg
cgtgagccccaggccaccgtggtcttcaccacccatgtgcccacgctgggccgctatgcc
ttcctgctgcacggctaccagccagcccaccccaccttccccgtggaagtcctcatcaac
gccggccgcgtgtggcagggccacgccaacgccagcttctgtccacatggctacggctgc
cgcaccctggtggtgtgtgagggccaggccctgctggacgtgacccacagcgagctcact
gtgaccgtgcgtgtgcccaagggccggtggctctggctggattatgtactcgtggtccct
gagaacgtctacagctttggctacctccgggaggagcccctggataaatcctatgacttc
atcagccactgcgcagcccagggctaccacatcagccccagcagctcatccctgttctgc
cgaaacgctgctgcttccctctccctcttctataacaacggagcccgtccatgtggctgc
cacgaagtaggtgctacaggccccacgtgtgagcccttcgggggccagtgtccctgccat
gcccatgtcattggccgtgactgctcccgctgtgccaccggatactggggcttccccaac
tgcaggccctgtgactgcggtgcccgcctctgtgacgagctcacgggccagtgcatctgc
ccgccacgcaccatcccgcccgactgcctgctgtgccagccccagacctttggctgccac
cccctggtcggctgtgaggagtgtaactgctcagggcccggcatccaggagctcacagac
cctacctgtgacacagacagcggccagtgcaagtgcagacccaacgtgactgggcgccgc
tgtgatacctgctctccgggcttccatggctacccccgctgccgcccctgtgactgtcac
gaggcgggcactgcgcctggcgtgtgtgaccccctcacagggcagtgctactgtaaggag
aacgtgcagggccccaaatgtgaccagtgcagccttgggaccttctcactggatgctgcc
aaccccaaaggttgcacccgctgcttctgctttggggccacggagcgctgccggagctcg
tcctacacccgccaggagttcgtggatatggagggatgggtgctgctgagcactgaccgg
caggtggtgccccacgagcggcagccagggacggagatgctccgtgcagacctgcggcac
gtgcctgaggctgtgcccgaggctttccccgagctgtactggcaggccccaccctcctac
ctgggggaccgggtgtcatcctacggtgggaccctccgttatgaactgcactcagagacc
cagcggggagatgtctttgtccccatggagagcaggccggatgtggtgctgcagggcaac
cagatgagcatcacattcctggagccggcataccccacgcctggccacgttcaccgtggg
cagctgcagctggtggaggggaacttccggcatacggagacgcgcaacactgtgtcccgc
gaggagctcatgatggtgctggccagcctggagcagctgcagatccgtgccctcttctca
cagatctcctcggctgtcttcctgcgcagggtggcactggaggtggccagcccagcaggc
cagggggccctggccagcaatgtggagctgtgcctgtgccccgccagctaccggggggac
tcatgccaggaatgtgcccccggcttctatcgggacgtcaaaggtctcttcctgggccga
tgtgtcccttgtcagtgccatggacactcagaccgctgcctccctggctctggcgtctgt
gtggactgccagcacaacaccgaaggggcccactgtgagcgctgccaggctggcttcgtg
agcagcagggacgaccccagcgccccctgtgtcagctgcccctgccccctctcagtgcct
tccaacaacttcgccgagggctgtgtcctgcgaggcggccgcacccagtgcctctgcaaa
cctggttatgcaggtgcctcctgcgagcggtgtgcgcccggattctttgggaacccactg
gtgctgggcagctcctgccagccatgcgactgcagcggcaacggtgaccccaacttgctc
ttcagcgactgcgaccccctgacgggcgcctgccgtggctgcctgcgccacaccactggg
ccccgctgcgagatctgtgcccccggcttctacggcaacgccctgctgcccggcaactgc
acccggtgcgactgtaccccatgtgggacagaggcctgcgacccccacagcgggcactgc
ctgtgcaaggcgggcgtgactgggcggcgctgtgaccgctgccaggagggacattttggt
ttcgatggctgcgggggctgccgcccgtgtgcttgtggaccggccgccgagggctccgag
tgccacccccagagcggacagtgccactgccgaccagggaccatgggaccccagtgccgc
gagtgtgcccctggctactgggggctccctgagcagggctgcaggcgctgccagtgccct
gggggccgctgtgaccctcacacgggccgctgcaactgccccccggggctcagcggggag
cgctgcgacacctgcagccagcagcatcaggtgcctgttccaggcgggcctgtgggccac
agcatccactgtgaagtgtgtgaccactgtgtggtcctgctcctggatgacctggaacgg
gccggcgccctcctccccgccattcacgagcaactgcgtggcatcaatgccagctccatg
gcctgggcccgtctgcacaggctgaacgcctccatcgctgacctgcagagccagctccgg
agccccctgggcccccgccatgagacggcacagcagctggaggtgctggagcagcagagc
acaagcctcgggcaggacgcacggcggctaggcggccaggccgtggggacccgagaccag
gcgagccaattgctggccggcaccgaggccacactgggccatgcgaagacgctgttggcg
gccatccgggctgtggaccgcaccctgagcgagctcatgtcccagacgggccacctgggg
ctggccaatgcctcggctccatcaggtgagcagctgctccggacactggccgaggtggag
cggctgctctgggagatgcgggcccgggacctgggggccccgcaggcagcagctgaggct
gagttggctgcagcacagagattgctggcccgggtgcaggagcagctgagcagcctctgg
gaggagaaccaggcactggccacacaaacccgcgaccggctggcccagcacgaggccggc
ctcatggacctgcgagaggctttgaaccgggcagtggacgccacacgggaggcccaggag
ctcaacagccgcaaccaggagcgcctggaggaagccctgcaaaggaagcaggagctgtcc
cgggacaatgccaccctgcaggccactctgcatgcggctagggacaccctggccagcgtc
ttcagattgctgcacagcctggaccaggctaaggaggagctggagcgcctcgccgccagc
ctggacggggctcggaccccactgctgcagaggatgcagaccttctccccggcgggcagc
aagctgcgtctagtggaggccgccgaggcccacgcacagcagctgggccagctggcactc
aatctgtccagcatcatcctggacgtcaaccaggaccgcctcacccagagggccatcgag
gcctccaacgcctacagccgcatcctgcaggccgtgcaggctgccgaggatgctgctggc
caggccctgcagcaggcggaccacacgtgggcgacggtggtgcggcagggcctggtggac
cgagcccagcagctcctggccaacagcactgcactagaagaggccatgctccaggaacag
cagaggctgggccttgtgtgggctgccctccagggtgccaggacccagctccgagatgtc
cgggccaagaaggaccagctggaggcgcacatccaggcggcgcaggccatgcttgccatg
gacacagacgagacaagcaagaagatcgcacatgccaaggctgtggctgctgaagcccag
gacaccgccacccgtgtgcagtcccagctgcaggccatgcaggagaatgtggagcggtgg
cagggccagtacgagggcctgcggggccaggacctgggccaggcagtgcttgacgcaggc
cactcagtgtccaccctggagaagacgctgccccagctgctggccaagctgagcatcctg
gagaaccgtggggtgcacaacgccagcctggccctgtccgccagcattggccgcgtgcga
gagctcattgcccaggcccggggggctgccagtaaggtcaaggtgcccatgaagttcaac
gggcgctcaggggtgcagctgcgcaccccacgggatcttgccgaccttgctgcctacact
gccctcaagttctacctgcagggcccagagcctgagcctgggcagggtaccgaggatcgc
tttgtgatgtacatgggcagccgccaggccactggggactacatgggtgtgtctctgcgt
gacaagaaggtgcactgggtgtatcagctgggtgaggcgggccctgcagtcctaagcatc
gatgaggacattggggagcagttcgcagctgtcagcctggacaggactctccagtttggc
cacatgtccgtcacagtggagagacagatgatccaggaaaccaagggtgacacggtggcc
cctggggcagaggggctgctcaacctgcggccagacgacttcgtcttctacgtcgggggg
taccccagtaccttcacgccccctcccctgcttcgcttccccggctaccggggctgcatc
gagatggacacgctgaatgaggaggtggtcagcctctacaacttcgagaggaccttccag
ctggacacggctgtggacaggccttgtgcccgctccaagtcgaccggggacccgtggctc
acggacggctcctacctggacggcaccggcttcgcccgcatcagcttcgacagtcagatc
agcaccaccaagcgcttcgagcaggagctgcggctcgtgtcctacagcggggtgctcttc
ttcctgaagcagcagagccagttcctgtgcttggccgtgcaagaaggcagcctcgtgctg
ttgtatgactttggggctggcctgaaaaaggccgtcccactgcagcccccaccgcccctg
acctcggccagcaaggcgatccaggtgttcctgctggggggcagccgcaagcgtgtgctg
gtgcgtgtggagcgggccacggtgtacagcgtggagcaggacaatgatctggagctggcc
gacgcctactacctggggggcgtgccgcccgaccagctgcccccgagcctgcgacggctc
ttccccaccggaggctcagtccgtggctgcgtcaaaggcatcaaggccctgggcaagtat
gtggacctcaagcggctgaacacgacaggcgtgagcgccggctgcaccgccgacctgctg
gtggggcgcgccatgactttccatggccacggcttccttcgcctggcgctctcgaacgtg
gcaccgctcactggcaacgtctactccggcttcggcttccacagcgcccaggacagtgcc
ctgctctactaccgggcgtccccggatgggctatgccaggtgtccctgcagcagggccgt
gtgagcctacagctcctgaggactgaagtgaaaactcaagcgggcttcgccgatggtgcc
ccccattacgtcgccttctacagcaatgccacgggagtctggctgtatgtcgatgaccag
ctccagcagatgaagccccaccggggaccaccccccgagctccagccgcagcctgagggg
cccccgaggctcctcctgggaggcctgcctgagtctggcaccatttacaacttcagtggc
tgcatcagcaacgtcttcgtgcagcggctcctgggcccacagcgcgtatttgatctgcag
cagaacctgggcagcgtcaatgtgagcacgggctgtgcacccgccctgcaagcccagacc
ccgggcctggggcctagaggactgcaggccaccgcccggaaggcctcccgccgcagccgt
cagcccgcccggcatcctgcctgcatgctgcccccacacctcaggaccacccgagactcc
taccagtttgggggttccctgtccagtcacctggagtttgtgggcatcctggcccgacat
aggaactggcccagtctctccatgcacgtcctcccgcgaagctcccgaggcctcctcctc
ttcactgcccgtctgaggcccggcagcccctccctggcgctcttcctgagcaatggccac
ttcgttgcacagatggaaggcctcgggactcggctccgcgcccagagccgccagcgctcc
cggcctggccgctggcacaaggtctccgtgcgctgggagaagaaccggatcctgctggtg
acggacggggcccgggcctggagccaggaggggccgcaccggcagcaccagggggcagag
cacccccagccccacaccctctttgtgggcggcctcccggccagcagccacagctccaaa
cttccggtgaccgtcgggttcagcggctgtgtgaagagactgaggctgcacgggaggccc
ctgggggcccccacacggatggcaggggtcacaccctgcatcttgggccccctggaggcg
ggcctgttcttcccaggcagcgggggagttatcactttagacctcccaggagctacactg
cctgatgtgggcctggaactggaggtgcggcccctggcagtcaccggactgatcttccac
ttgggccaggcccggacgcccccctacttgcagttgcaggtgaccgagaagcaagtcctg
ctgcgggcggatgacggagcaggggagttctccacgtcagtgacccgcccctcagtgctg
tgtgatggccagtggcaccggctagcggtgatgaaaagcgggaatgtgctccggctggag
gtggacgcgcagagcaaccacaccgtgggccccttgctggcggctgcagctggtgcccca
gcccctctgtacctcgggggcctgcctgagcccatggccgtgcagccctggccccccgcc
tactgcggctgcatgaggaggctggcggtgaaccggtcccccgtcgccatgactcgctct
gtggaggtccacggggcagtgggggccagtggctgcccagccgcctag

KEGG   Homo sapiens (human): 3912Help
Entry
3912              CDS       T01001                                 

Gene name
LAMB1, CLM, LIS5
Definition
(RefSeq) laminin subunit beta 1
  KO
K05636  laminin, beta 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Disease
H00268  Lissencephaly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3912 (LAMB1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3912 (LAMB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3912 (LAMB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3912 (LAMB1)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    3912 (LAMB1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3912 (LAMB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    3912 (LAMB1)
   05145 Toxoplasmosis
    3912 (LAMB1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Laminin_EGF Laminin_N CorA F5_F8_type_C
Motif
Other DBs
NCBI-GeneID: 3912
NCBI-ProteinID: NP_002282
OMIM: 150240
HGNC: 6486
Ensembl: ENSG00000091136
Vega: OTTHUMG00000149966
Pharos: P07942(Tbio)
UniProt: P07942 Q8TAS6
LinkDB All DBs
Structure
PDB: 

Position
7q31.1
AA seq 1786 aa AA seqDB search
MGLLQLLAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHK
PEPYCIVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVEN
VTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTG
PMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKL
HTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMC
RHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGG
VCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTG
LIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY
CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC
NEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEGAYLEFF
IDNIPYSMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTIPDDDNQVVSLSPG
SRYVVLPRPVCFEKGTNYTVRLELPQYTSSDSDVESPYTLIDSLVLMPYCKSLDIFTVGG
SGDGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGS
LSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQC
HCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLA
GYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCAS
GYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA
LQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTG
CDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIE
TPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRF
LEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDV
TEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDS
ITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDE
LAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNA
WQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEEL
RNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVI
LQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDI
QGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVK
QSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLL
KDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAVYSTCL
NT seq 5361 nt NT seq  +upstreamnt  +downstreamnt
atggggcttctccagttgctagctttcagtttcttagccctgtgcagagcccgagtgcgc
gctcaggaacccgagttcagctacggctgcgcagaaggcagctgctatcccgccacgggc
gaccttctcatcggccgagcacagaagctttcggtgacctcgacgtgcgggctgcacaag
cccgaaccctactgtatcgtcagccacttgcaggaggacaaaaaatgcttcatatgcaat
tcccaagatccttatcatgagaccctgaatcctgacagccatctcattgaaaatgtggtc
actacatttgctccaaaccgccttaagatttggtggcaatctgaaaatggtgtggaaaat
gtaactatccaactggatttggaagcagaattccattttactcatctcataatgactttc
aagacattccgtccagctgctatgctgatagaacgatcgtccgactttgggaaaacctgg
ggtgtgtatagatacttcgcctatgactgtgaggcctcgtttccaggcatttcaactggc
cccatgaaaaaagtcgatgacataatttgtgattctcgatattctgacattgaaccctca
actgaaggagaggtgatatttcgtgctttagatcctgctttcaaaatagaagatccttat
agcccaaggatacagaatttattaaaaattaccaacttgagaatcaagtttgtgaaactg
catactttgggagataaccttctggattccaggatggaaatcagagaaaagtattattat
gcagtttatgatatggtggttcgaggaaattgcttctgctatggtcatgccagcgaatgt
gcccctgtggatggattcaatgaagaagtggaaggaatggttcacggacactgcatgtgc
aggcataacaccaagggcttaaactgtgaactctgcatggatttctaccatgatttacct
tggagacctgctgaaggccgaaacagcaacgcctgtaaaaaatgtaactgcaatgaacat
tccatctcttgtcactttgacatggctgtttacctggccacggggaacgtcagcggaggc
gtgtgtgatgactgtcagcacaacaccatggggcgcaactgtgagcagtgcaagccgttt
tactaccagcacccagagagggacatccgagatcctaatttctgtgaacgatgtacgtgt
gacccagctggctctcaaaatgagggaatttgtgacagctatactgatttttctactggt
ctcattgctggccagtgtcggtgtaaattaaatgtggaaggagaacattgtgatgtttgc
aaagaaggcttctatgatttaagcagtgaagatccatttggttgtaaatcttgtgcttgc
aatcctctgggaacaattcctggagggaatccttgtgattccgagacaggtcactgctac
tgcaagcgtctggtgacaggacagcattgtgaccagtgcctgccagagcactggggctta
agcaatgatttggatggatgtcgaccatgtgactgtgaccttgggggagccttaaacaac
agttgctttgcggagtcaggccagtgctcatgccggcctcacatgattggacgtcagtgc
aacgaagtggaacctggttactactttgccaccctggatcactacctctatgaagcggag
gaagccaacttggggcctggggttagcatagtggagcggcaatatatccaggaccggatt
ccctcctggactggagccggcttcgtccgagtgcctgaaggggcttatttggagtttttc
attgacaacataccatattccatggagtacgacatcctaattcgctacgagccacagcta
cccgaccactgggaaaaagctgtcatcacagtgcagcgacctggaaggattccaaccagc
agccgatgtggtaataccatccccgatgatgacaaccaggtggtgtcattatcaccaggc
tcaagatatgtcgtccttcctcggccggtgtgctttgagaagggaacaaactacacggtg
aggttggagctgcctcagtacacctcctctgatagcgacgtggagagcccctacacgctg
atcgattctcttgttctcatgccatactgtaaatcactggacatcttcaccgtgggaggt
tcaggagatggggtggtcaccaacagtgcctgggaaacctttcagagataccgatgtcta
gagaacagcagaagcgttgtgaaaacaccgatgacagatgtttgcagaaacatcatcttt
agcatttctgccctgttacaccagacaggcctggcttgtgaatgcgaccctcagggttcg
ttaagttccgtgtgtgatcccaacggaggccagtgccagtgccggcccaacgtggttgga
agaacctgcaacagatgtgcacctggaacttttggctttggccccagtggatgcaaacct
tgtgagtgccatctgcaaggatctgtcaatgccttctgcaatcccgtcactggccagtgc
cactgtttccagggagtgtatgctcggcagtgtgatcggtgcttacctgggcactggggc
tttccaagttgccagccctgccagtgcaatggccacgccgatgactgcgacccagtgact
ggggagtgcttgaactgccaggactacaccatgggtcataactgtgaaaggtgcttggct
ggttactatggcgaccccatcattgggtcaggagatcactgccgcccttgcccttgccca
gatggtcccgacagtggacgccagtttgccaggagctgctaccaagatcctgttacttta
cagcttgcctgtgtttgtgatcctggatacattggttccagatgtgacgactgtgcctca
ggatactttggcaatccatcagaagttggggggtcgtgtcagccttgccagtgtcacaac
aacattgacacgacagacccagaagcctgtgacaaggagactgggaggtgtctcaagtgc
ctgtaccacacggaaggggaacactgtcagttctgccggtttggatactatggtgatgcc
ctccagcaggactgtcgaaagtgtgtctgtaattacctgggcaccgtgcaagagcactgt
aacggctctgactgccagtgcgacaaagccactggtcagtgcttgtgtcttcctaatgtg
atcgggcagaactgtgaccgctgtgcgcccaatacctggcagctggccagtggcactggc
tgtgacccatgcaactgcaatgctgctcattccttcgggccatcttgcaatgagttcacg
gggcagtgccagtgcatgcctgggtttggaggccgcacctgcagcgagtgccaggaactc
ttctggggagaccccgacgtggagtgccgagcctgtgactgtgaccccaggggcattgag
acgccacagtgtgaccagtccacgggccagtgtgtctgcgttgagggtgttgagggtcca
cgctgtgacaagtgcacgcgagggtactcgggggtcttccctgactgcacaccctgccac
cagtgctttgctctctgggatgtgatcattgccgagctgaccaacaggacacacagattc
ctggagaaagccaaggccttgaagatcagtggtgtgatcgggccttaccgtgagactgtg
gactcggtggagaggaaagtcagcgagataaaagacatcctggcgcagagccccgcagca
gagccactgaaaaacattgggaatctctttgaggaagcagagaaactgattaaagatgtt
acagaaatgatggctcaagtagaagtgaaattatctgacacaacttcccaaagcaacagc
acagccaaagaactggattctctacagacagaagccgaaagcctagacaacactgtgaaa
gaacttgctgaacaactggaatttatcaaaaactcagatattcggggtgccttggatagc
attaccaagtatttccagatgtctcttgaggcagaggagagggtgaatgcctccaccaca
gaacccaacagcactgtggagcagtcagccctcatgagagacagagtagaagacgtgatg
atggagcgagaatcccagttcaaggaaaaacaagaggagcaggctcgcctccttgatgaa
ctggcaggcaagctacaaagcctagacctttcagccgctgccgaaatgacctgtggaaca
cccccaggggcctcctgttccgagactgaatgtggcgggccaaactgcagaactgacgaa
ggagagaggaagtgtggggggcctggctgtggtggtctggttactgttgcacacaacgcc
tggcagaaagccatggacttggaccaagatgtcctgagtgccctggctgaagtggaacag
ctctccaagatggtctctgaagcaaaactgagggcagatgaggcaaaacaaagtgctgaa
gacattctgttgaagacaaatgctaccaaagaaaaaatggacaagagcaatgaggagctg
agaaatctaatcaagcaaatcagaaactttttgacccaggatagtgctgatttggacagc
attgaagcagttgctaatgaagtattgaaaatggagatgcctagcaccccacagcagtta
cagaacttgacagaagatatacgtgaacgagttgaaagcctttctcaagtagaggttatt
cttcagcatagtgctgctgacattgccagagctgagatgttgttagaagaagctaaaaga
gcaagcaaaagtgcaacagatgttaaagtcactgcagatatggtaaaggaagctctggaa
gaagcagaaaaggcccaggtcgcagcagagaaggcaattaaacaagcagatgaagacatt
caaggaacccagaacctgttaacttcgattgagtctgaaacagcagcttctgaggaaacc
ttgttcaacgcgtcccagcgcatcagcgagttagagaggaatgtggaagaacttaagcgg
aaagctgcccaaaactccggggaggcagaatatattgaaaaagtagtatatactgtgaag
caaagtgcagaagatgttaagaagactttagatggtgaacttgatgaaaagtataaaaaa
gtagaaaatttaattgccaaaaaaactgaagagtcagctgatgccagaaggaaagccgaa
atgctacaaaatgaagcaaaaactcttttagctcaagcaaatagcaagctgcaactgctc
aaagatttagaaagaaaatatgaagacaatcaaagatacttagaagataaagctcaagaa
ttagcaagactggaaggagaagtccgttcactcctaaaggatataagccagaaagttgct
gtgtatagcacatgcttgtaa

KEGG   Homo sapiens (human): 3913Help
Entry
3913              CDS       T01001                                 

Gene name
LAMB2, LAMS, NPHS5
Definition
(RefSeq) laminin subunit beta 2
  KO
K06243  laminin, beta 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Disease
H00576  Pierson syndrome
H01657  Nephrotic syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3913 (LAMB2)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3913 (LAMB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3913 (LAMB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3913 (LAMB2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    3913 (LAMB2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3913 (LAMB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    3913 (LAMB2)
   05145 Toxoplasmosis
    3913 (LAMB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Laminin_EGF Laminin_N Sec5 F5_F8_type_C DUF720
Motif
Other DBs
NCBI-GeneID: 3913
NCBI-ProteinID: NP_002283
OMIM: 150325
HGNC: 6487
Ensembl: ENSG00000172037
Vega: OTTHUMG00000156807
Pharos: P55268(Tbio)
UniProt: P55268 A0A024R319
LinkDB All DBs
Position
3p21.31
AA seq 1798 aa AA seqDB search
MELTSRERGRGQPLPWELRLGLLLSVLAATLAQAPAPDVPGCSRGSCYPATGDLLVGRAD
RLTASSTCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRR
AAWWQSENGIPAVTIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSY
DCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLL
KITNLRVNLTRLHTLGDNLLDPRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPA
HAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDM
AVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDG
GRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPG
STPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQ
CHCRQHMVGRRCEQVQPGYFRPFLDHLIWEAEDTRGQVLDVVERLVTPGETPSWTGSGFV
RLQEGQTLEFLVASVPKAMDYDLLLRLEPQVPEQWAELELIVQRPGPVPAHSLCGHLVPK
DDRIQGTLQPHARYLIFPNPVCLEPGISYKLHLKLVRTGGSAQPETPYSGPGLLIDSLVL
LPRVLVLEMFSGGDAAALERQATFERYQCHEEGLVPSKTSPSEACAPLLISLSTLIYNGA
LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALS
SLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHT
GGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGY
TGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCA
HCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCA
PNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQC
HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDRV
VQDLAARTQRLEQRAQELQQTGVLGAFESSFWHMQEKLGIVQGIVGARNTSAASTAQLVE
ATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQHLDL
LKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKEDFN
SKHMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGL
SCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRRQASEAQQRAQAALDKANA
SRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAIA
ERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGI
AQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLA
ASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARD
LLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRSVLQAINLQVQIYNTCQ
NT seq 5397 nt NT seq  +upstreamnt  +downstreamnt
atggagctgacctcaagggaaagagggaggggacagcctctgccctgggaacttcgactg
ggcctactgctaagcgtgctggctgccacactggcacaggcccctgccccggatgtgcct
ggctgttccaggggaagctgctaccccgccacgggcgacctgctggtgggccgagctgac
agactgactgcctcatccacttgtggcctgaatggcccccagccctactgcatcgtcagt
cacctgcaggacgaaaagaagtgcttcctttgtgactcccggcgccccttctctgctaga
gacaacccacacagccatcgcatccagaatgtagtcaccagctttgcaccacagcggcgg
gcagcctggtggcagtcagagaatggtatccctgcggtcaccatccagctggacctggag
gctgagtttcatttcacacacctcattatgaccttcaagacatttcgccctgctgccatg
ctggtggaacgctcagcagactttggccgcacctggcatgtgtaccgatatttctcctat
gactgtggggctgacttcccaggagtcccactagcacccccacggcactgggatgatgta
gtctgtgagtcccgctactcagagattgagccatccactgaaggcgaggtcatctatcgt
gtgctggaccctgccatccctatcccagacccctacagctcacggattcagaacctgttg
aagatcaccaacctacgggtgaacctgactcgtctacacacgttgggagacaacctactc
gacccacggagggagatccgagagaagtactactatgccctctatgagctggttgtacgt
ggcaactgcttctgctacggacacgcctcagagtgtgcacccgccccaggggcaccagcc
catgctgagggcatggtgcacggagcttgcatctgcaaacacaacacacgtggcctcaac
tgcgagcagtgtcaggatttctatcgtgacctgccctggcgtccggctgaggacggccat
agtcatgcctgtaggaagtgtgagtgccatgggcacacccacagctgccacttcgacatg
gccgtatacctggcatctggcaatgtgagtggaggtgtgtgtgatggatgtcagcataac
acagctgggcgccactgtgagctctgtcggcccttcttctaccgtgacccaaccaaggac
ctgcgggatccggctgtgtgccgctcctgtgattgtgaccccatgggttctcaagacggt
ggtcgctgtgattcccatgatgaccctgcactgggactggtctccggccagtgtcgctgc
aaagaacatgtggtgggcactcgctgccagcaatgccgtgatggcttctttgggctcagc
atcagtgaccgtctgggctgccggcgatgtcaatgtaatgcacggggcacagtgcctggg
agcactccttgtgaccccaacagtggatcctgttactgcaaacgtctagtgactggacgt
ggatgtgaccgctgcctgcctggccactggggcctgagccacgacctgctcggctgccgc
ccctgtgactgcgacgtgggtggtgctttggatccccagtgtgatgagggcacaggtcaa
tgccactgccgccagcacatggttgggcgacgctgtgagcaggtgcaacctggctacttc
cggcccttcctggaccacctaatttgggaggctgaggacacccgagggcaggtgctcgat
gtggtggagcgcctggtgacccccggggaaactccatcctggactggctcaggcttcgtg
cggctacaggaaggtcagaccctggagttcctggtggcctctgtgccgaaggctatggac
tatgacctgctgctgcgcttagagccccaggtccctgagcaatgggcagagttggaactg
attgtgcagcgtccagggcctgtgcctgcccacagcctgtgtgggcatttggtgcccaag
gatgatcgcatccaagggactctgcaaccacatgccaggtacttgatatttcctaatcct
gtctgccttgagcctggtatctcctacaagctgcatctgaagctggtacggacaggggga
agtgcccagcctgagactccctactctggacctggcctgctcattgactcgctggtgctg
ctgccccgtgtcctggtgctagagatgtttagtgggggtgatgctgctgccctggagcgc
caggccacctttgaacgctaccaatgccatgaggagggtctggtgcccagcaagacttct
ccctctgaggcctgcgcacccctcctcatcagcctgtccaccctcatctacaatggtgcc
ctgccatgtcagtgcaaccctcaaggttcactgagttctgagtgcaaccctcatggtggt
cagtgcctgtgcaagcctggagtggttgggcgccgctgtgacctctgtgcccctggctac
tatggctttggccccacaggctgtcaagcctgccagtgcagccacgagggggcactcagc
agtctctgtgaaaagaccagtgggcaatgtctctgtcgaactggtgcctttgggcttcgc
tgtgaccgctgccagcgtggccagtggggattccctagctgccggccatgtgtctgcaat
gggcatgcagatgagtgcaacacccacacaggcgcttgcctgggctgccgtgatcacaca
gggggtgagcactgtgaaaggtgcattgctggtttccacggggacccacggctgccatat
gggggccagtgccggccctgtccctgtcctgaaggccctgggagccaacggcactttgct
acttcttgccaccaggatgaatattcccagcagattgtgtgccactgccgggcaggctat
acggggctgcgatgtgaagcttgtgcccctgggcactttggggacccatcaaggccaggt
ggccggtgccaactgtgtgagtgcagtgggaacattgacccaatggatcctgatgcctgt
gacccccacacggggcaatgcctgcgctgtttacaccacacagagggtccacactgtgcc
cactgcaagcctggcttccatgggcaggctgcccgacagagctgtcaccgctgcacatgc
aacctgctgggcacaaatccgcagcagtgcccatctcctgaccagtgccactgtgatcca
agcagtgggcagtgcccatgcctccccaatgtccagggccctagctgtgaccgctgtgcc
cccaacttctggaacctcaccagtggccatggttgccagccttgtgcctgccacccaagc
cgggccagaggccccacctgcaacgagttcacagggcagtgccactgccgtgccggcttt
ggagggcggacttgttctgagtgccaagagctccactggggagaccctgggttgcagtgc
catgcctgtgattgtgactctcgtggaatagatacacctcagtgtcaccgcttcacaggt
cactgcagctgccgcccaggggtgtctggtgtgcgctgtgaccagtgtgcccgtggcttc
tcaggaatctttcctgcctgccatccctgccatgcatgcttcggggattgggaccgagtg
gtgcaggacttggcagcccgtacacagcgcctagagcagcgggcgcaggagttgcaacag
acgggtgtgctgggtgcctttgagagcagcttctggcacatgcaggagaagctgggcatt
gtgcagggcatcgtaggtgcccgcaacacctcagccgcctccactgcacagcttgtggag
gccacagaggagctgcggcgtgaaattggggaggccactgagcacctgactcagctcgag
gcagacctgacagatgtgcaagatgagaacttcaatgccaaccatgcactaagtggtctg
gagcgagataggcttgcacttaatctcacactgcggcagctcgaccagcatcttgacttg
ctcaaacattcaaacttcctgggtgcctatgacagcatccggcatgcccatagccagtct
gcagaggcagaacgtcgtgccaatacctcagccctggcagtacctagccctgtgagcaac
tcggcaagtgctcggcatcggacagaggcactgatggatgctcagaaggaggacttcaac
agcaaacacatggccaaccagcgggcacttggcaagctctctgcccatacccacaccctg
agcctgacagacataaatgagctggtgtgtggggcaccaggggatgcaccctgtgctaca
agcccttgtgggggtgccggctgtcgagatgaggatgggcagccgcgctgtgggggcctc
agctgcaatggggcagcggctacagcagacctagcactgggccgggcccggcacacacag
gcagagctgcagcgggcactggcagaaggtggtagcatcctcagcagagtggctgagact
cgtcggcaggcaagcgaggcacagcagcgggcccaggcagccctggacaaggctaatgct
tccaggggacaggtggaacaggccaaccaggaacttcaagaacttatccagagtgtgaag
gacttcctcaaccaggagggggctgatcctgatagcattgaaatggtggccacacgggtg
ctagagctctccatcccagcttcagctgagcagatccagcacctggcgggtgcgattgca
gagcgagtccggagcctggcagatgtggatgcgatcctggcacgtactgtaggagatgtg
cgtcgtgccgagcagctactgcaggatgcacggcgggcaaggagctgggctgaggatgag
aaacagaaggcagagacagtacaggcagcactggaggaggcccagcgggcacagggtatt
gcccagggtgccatccggggggcagtggctgacacacgggacacagagcagaccctgtac
caggtacaggagaggatggcaggtgcagagcgggcactgagctctgcaggtgaaagggct
cggcagttggatgctctcctggaggctctgaaattgaaacgggcaggaaatagtctggca
gcctctacagcagaagaaacggcaggcagtgcccagggtcgtgcccaggaggctgagcag
ctgctacgcggtcctctgggtgatcagtaccagacggtgaaggccctagctgagcgcaag
gcccaaggtgtgctggctgcacaggcaagggcagaacaactgcgggatgaggctcgggac
ctgttgcaagccgctcaggacaagctgcagcggctacaggaattggaaggcacctatgag
gaaaatgagcgggcactggagagtaaggcagcccagttggacgggttggaggccaggatg
cgcagcgtgcttcaagccatcaacttgcaggtgcagatctacaacacctgccagtga

KEGG   Homo sapiens (human): 3914Help
Entry
3914              CDS       T01001                                 

Gene name
LAMB3, AI1A, BM600-125KDA, LAM5, LAMNB1
Definition
(RefSeq) laminin subunit beta 3
  KO
K06244  laminin, beta 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Disease
H00586  Epidermolysis bullosa, junctional
H00615  Amelogenesis imperfecta
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3914 (LAMB3)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3914 (LAMB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3914 (LAMB3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3914 (LAMB3)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    3914 (LAMB3)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3914 (LAMB3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    3914 (LAMB3)
   05145 Toxoplasmosis
    3914 (LAMB3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Laminin_N Laminin_EGF Laminin_II F5_F8_type_C DUF745 BNR_6 COMP
Motif
Other DBs
NCBI-GeneID: 3914
NCBI-ProteinID: NP_000219
OMIM: 150310
HGNC: 6490
Ensembl: ENSG00000196878
Vega: OTTHUMG00000036360
Pharos: Q13751(Tbio)
UniProt: Q13751 A0A0S2Z3R6
LinkDB All DBs
Position
1q32.2
AA seq 1172 aa AA seqDB search
MRPFFLLCFALPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYG
EWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNPVSLQLDLDRRFQLQEVM
MEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRP
NARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYA
VSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNR
PWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQL
HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL
TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP
CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG
TEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRFG
RLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRR
TLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLST
AYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEMSSLPDL
TPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR
GFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLT
DPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARAR
RLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQ
VLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFER
IKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAI
MLRSADLTGLEKRVEQIRDHINGRVLYYATCK
NT seq 3519 nt NT seq  +upstreamnt  +downstreamnt
atgagaccattcttcctcttgtgttttgccctgcctggcctcctgcatgcccaacaagcc
tgctcccgtggggcctgctatccacctgttggggacctgcttgttgggaggacccggttt
ctccgagcttcatctacctgtggactgaccaagcctgagacctactgcacccagtatggc
gagtggcagatgaaatgctgcaagtgtgactccaggcagcctcacaactactacagtcac
cgagtagagaatgtggcttcatcctccggccccatgcgctggtggcagtcacagaatgat
gtgaaccctgtctctctgcagctggacctggacaggagattccagcttcaagaagtcatg
atggagttccaggggcccatgcccgccggcatgctgattgagcgctcctcagacttcggt
aagacctggcgagtgtaccagtacctggctgccgactgcacctccaccttccctcgggtc
cgccagggtcggcctcagagctggcaggatgttcggtgccagtccctgcctcagaggcct
aatgcacgcctaaatggggggaaggtccaacttaaccttatggatttagtgtctgggatt
ccagcaactcaaagtcaaaaaattcaagaggtgggggagatcacaaacttgagagtcaat
ttcaccaggctggcccctgtgccccaaaggggctaccaccctcccagcgcctactatgct
gtgtcccagctccgtctgcaggggagctgcttctgtcacggccatgctgatcgctgcgca
cccaagcctggggcctctgcaggcccctccaccgctgtgcaggtccacgatgtctgtgtc
tgccagcacaacactgccggcccaaattgtgagcgctgtgcacccttctacaacaaccgg
ccctggagaccggcggagggccaggacgcccatgaatgccaaaggtgcgactgcaatggg
cactcagagacatgtcactttgaccccgctgtgtttgccgccagccagggggcatatgga
ggtgtgtgtgacaattgccgggaccacaccgaaggcaagaactgtgagcggtgtcagctg
cactatttccggaaccggcgcccgggagcttccattcaggagacctgcatctcctgcgag
tgtgatccggatggggcagtgccaggggctccctgtgacccagtgaccgggcagtgtgtg
tgcaaggagcatgtgcagggagagcgctgtgacctatgcaagccgggcttcactggactc
acctacgccaacccgcagggctgccaccgctgtgactgcaacatcctggggtcccggagg
gacatgccgtgtgacgaggagagtgggcgctgcctttgtctgcccaacgtggtgggtccc
aaatgtgaccagtgtgctccctaccactggaagctggccagtggccagggctgtgaaccg
tgtgcctgcgacccgcacaactccctcagcccacagtgcaaccagttcacagggcagtgc
ccctgtcgggaaggctttggtggcctgatgtgcagcgctgcagccatccgccagtgtcca
gaccggacctatggagacgtggccacaggatgccgagcctgtgactgtgatttccgggga
acagagggcccgggctgcgacaaggcatcaggccgctgcctctgccgccctggcttgacc
gggccccgctgtgaccagtgccagcgaggctactgtaatcgctacccggtgtgcgtggcc
tgccacccttgcttccagacctatgatgcggacctccgggagcaggccctgcgctttggt
agactccgcaatgccaccgccagcctgtggtcagggcctgggctggaggaccgtggcctg
gcctcccggatcctagatgcaaagagtaagattgagcagatccgagcagttctcagcagc
cccgcagtcacagagcaggaggtggctcaggtggccagtgccatcctctccctcaggcga
actctccagggcctgcagctggatctgcccctggaggaggagacgttgtcccttccgaga
gacctggagagtcttgacagaagcttcaatggtctccttactatgtatcagaggaagagg
gagcagtttgaaaaaataagcagtgctgatccttcaggagccttccggatgctgagcaca
gcctacgagcagtcagcccaggctgctcagcaggtctccgacagctcgcgccttttggac
cagctcagggacagccggagagaggcagagaggctggtgcggcaggcgggaggaggagga
ggcaccggcagccccaagcttgtggccctgaggctggagatgtcttcgttgcctgacctg
acacccaccttcaacaagctctgtggcaactccaggcagatggcttgcaccccaatatca
tgccctggtgagctatgtccccaagacaatggcacagcctgtggctcccgctgcaggggt
gtccttcccagggccggtggggccttcttgatggcggggcaggtggctgagcagctgcgg
ggcttcaatgcccagctccagcggaccaggcagatgattagggcagccgaggaatctgcc
tcacagattcaatccagtgcccagcgcttggagacccaggtgagcgccagccgctcccag
atggaggaagatgtcagacgcacacggctcctaatccagcaggtccgggacttcctaaca
gaccccgacactgatgcagccactatccaggaggtcagcgaggccgtgctggccctgtgg
ctgcccacagactcagctactgttctgcagaagatgaatgagatccaggccattgcagcc
aggctccccaacgtggacttggtgctgtcccagaccaagcaggacattgcgcgtgcccgc
cggttgcaggctgaggctgaggaagccaggagccgagcccatgcagtggagggccaggtg
gaagatgtggttgggaacctgcggcaggggacagtggcactgcaggaagctcaggacacc
atgcaaggcaccagccgctcccttcggcttatccaggacagggttgctgaggttcagcag
gtactgcggccagcagaaaagctggtgacaagcatgaccaagcagctgggtgacttctgg
acacggatggaggagctccgccaccaagcccggcagcagggggcagaggcagtccaggcc
cagcagcttgcggaaggtgccagcgagcaggcattgagtgcccaagagggatttgagaga
ataaaacaaaagtatgctgagttgaaggaccggttgggtcagagttccatgctgggtgag
cagggtgcccggatccagagtgtgaagacagaggcagaggagctgtttggggagaccatg
gagatgatggacaggatgaaagacatggagttggagctgctgcggggcagccaggccatc
atgctgcgctcagcggacctgacaggactggagaagcgtgtggagcagatccgtgaccac
atcaatgggcgcgtgctctactatgccacctgcaagtga

KEGG   Homo sapiens (human): 3915Help
Entry
3915              CDS       T01001                                 

Gene name
LAMC1, LAMB2
Definition
(RefSeq) laminin subunit gamma 1
  KO
K05635  laminin, gamma 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05020  Prion diseases
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3915 (LAMC1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3915 (LAMC1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3915 (LAMC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3915 (LAMC1)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    3915 (LAMC1)
  09164 Neurodegenerative disease
   05020 Prion diseases
    3915 (LAMC1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3915 (LAMC1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    3915 (LAMC1)
   05145 Toxoplasmosis
    3915 (LAMC1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Laminin_EGF Laminin_N Laminin_B
Motif
Other DBs
NCBI-GeneID: 3915
NCBI-ProteinID: NP_002284
OMIM: 150290
HGNC: 6492
Ensembl: ENSG00000135862
Vega: OTTHUMG00000035418
Pharos: P11047(Tbio)
UniProt: P11047 Q6NVY8
LinkDB All DBs
Structure
PDB: 

Position
1q25.3
AA seq 1609 aa AA seqDB search
MRGSHRAAPALRPRGRLWPVLAVLAAAAAAGCAQAAMDECTDEGGRPQRCMPEFVNAAFN
VTVVATNTCGTPPEEYCVQTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQS
QTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSG
SCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVL
QEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECMKNEF
DKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRS
TGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKP
GVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPG
FFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISSTFQIDEDGWRAEQRDGSEASLEW
SSERQDIAVISDSYFPRYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGA
GLRVSVPLIAQGNSYPSETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTY
SERSAGYLDDVTLASARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSP
CVLCACNGHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSS
CAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVG
NCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNP
VTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGI
TGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYF
YNRSWPGCQECPACYRLVKDKVADHRVKLQELESLIANLGTGDEMVTDQAFEDRLKEAER
EVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVEN
TERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRV
AKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRA
GDKAVEIYASVAQLSPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELE
VKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDN
KTAAEEALRKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNA
TSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAE
INARKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSD
LENEAKKQEAAIMDYNRDIEEIMKDIRNLEDIRKTLPSGCFNTPSIEKP
NT seq 4830 nt NT seq  +upstreamnt  +downstreamnt
atgagagggagccatcgggccgcgccggccctgcggccccgggggcggctctggcccgtg
ctggccgtgctggcggcggccgccgcggcgggctgtgcccaggcagccatggacgagtgc
acggacgagggcgggcggccgcagcgctgcatgcccgagttcgtcaacgccgccttcaac
gtgactgtggtggccaccaacacgtgtgggactccgcccgaggaatactgtgtgcagacc
ggggtgaccggggtcaccaagtcctgtcacctgtgcgacgccgggcagccccacctgcag
cacggggcagccttcctgaccgactacaacaaccaggccgacaccacctggtggcaaagc
cagaccatgctggccggggtgcagtaccccagctccatcaacctcacgctgcacctggga
aaagcttttgacatcacctatgtgcgtctcaagttccacaccagccgcccggagagcttt
gccatttacaagcgcacacgggaagacgggccctggattccttaccagtactacagtggt
tcctgtgagaacacctactccaaggcaaaccgcggcttcatcaggacaggaggggacgag
cagcaggccttgtgtactgatgaattcagtgacatttctcccctcactgggggcaacgtg
gccttttctaccctggaaggaaggcccagcgcctataactttgacaatagccctgtgctg
caggaatgggtaactgccactgacatcagagtaactcttaatcgcctgaacacttttgga
gatgaagtgtttaacgatcccaaagttctcaagtcctattattatgccatctctgatttt
gctgtaggtggcagatgtaaatgtaatggacacgcaagcgagtgtatgaagaacgaattt
gataagctggtgtgtaattgcaaacataacacatatggagtagactgtgaaaagtgtctt
cctttcttcaatgaccggccgtggaggagggcaactgcggaaagtgccagtgaatgcctg
ccctgtgattgcaatggtcgatcccaggaatgctacttcgaccctgaactctatcgttcc
actggccatgggggccactgtaccaactgccaggataacacagatggcgcccactgtgag
aggtgccgagagaacttcttccgccttggcaacaatgaagcctgctcttcatgccactgt
agtcctgtgggctctctaagcacacagtgtgatagttacggcagatgcagctgtaagcca
ggagtgatgggggacaaatgtgaccgttgccagcctggattccattctctcactgaagca
ggatgcaggccatgctcttgtgatccctctggcagcatagatgaatgtaatattgaaaca
ggaagatgtgtttgcaaagacaatgtcgaaggcttcaattgtgaaagatgcaaacctgga
ttttttaatctggaatcatctaatcctcggggttgcacaccctgcttctgctttgggcat
tcttctgtctgtacaaacgctgttggctacagtgtttattctatctcctctacctttcag
attgatgaggatgggtggcgtgcggaacagagagatggctctgaagcatctctcgagtgg
tcctctgagaggcaagatatcgccgtgatctcagacagctactttcctcggtacttcatt
gctcctgcaaagttcttgggcaagcaggtgttgagttatggtcagaacctctccttctcc
tttcgagtggacaggcgagatactcgcctctctgcagaagaccttgtgcttgagggagct
ggcttaagagtatctgtacccttgatcgctcagggcaattcctatccaagtgagaccact
gtgaagtatgtcttcaggctccatgaagcaacagattacccttggaggcctgctcttacc
ccttttgaatttcagaagctcctaaacaacttgacctctatcaagatacgtgggacatac
agtgagagaagtgctggatatttggatgatgtcaccctggcaagtgctcgtcctgggcct
ggagtccctgcaacttgggtggagtcctgcacctgtcctgtgggatatggagggcagttt
tgtgagatgtgcctctcaggttacagaagagaaactcctaatcttggaccatacagtcca
tgtgtgctttgcgcctgcaatggacacagcgagacctgtgatcctgagacaggtgtttgt
aactgcagagacaatacggctggcccgcactgtgagaagtgcagtgatgggtactatgga
gattcaactgcaggcacctcctccgattgccaaccctgtccgtgtcctggaggttcaagt
tgtgctgttgttcccaagacaaaggaggtggtgtgcaccaactgtcctactggcaccact
ggtaagagatgtgagctctgtgatgatggctactttggagaccccctgggtagaaacggc
cctgtgagactttgccgcctgtgccagtgcagtgacaacatcgatcccaatgcagttgga
aattgcaatcgcttgacgggagaatgcctgaagtgcatctataacactgctggcttctat
tgtgaccggtgcaaagacggattttttggaaatcccctggctcccaatccagcagacaaa
tgcaaagcctgcaattgcaatctgtatgggaccatgaagcagcagagcagctgtaacccc
gtgacggggcagtgtgaatgtttgcctcacgtgactggccaggactgtggtgcttgtgac
cctggattctacaatctgcagagtgggcaaggctgtgagaggtgtgactgccatgccttg
ggctccaccaatgggcagtgtgacatccgcaccggccagtgtgagtgccagcccggcatc
actggtcagcactgtgagcgctgtgaggtcaaccactttgggtttggacctgaaggctgc
aaaccctgtgactgtcatcctgagggatctctttcacttcagtgcaaagatgatggtcgc
tgtgaatgcagagaaggctttgtgggaaatcgctgtgaccagtgtgaagaaaactatttc
tacaatcggtcttggcctggctgccaggaatgtccagcttgttaccggctggtaaaggat
aaggttgctgatcatagagtgaagctccaggaattagagagtctcatagcaaaccttgga
actggggatgagatggtgacagatcaagccttcgaggatagactaaaggaagcagagagg
gaagttatggacctccttcgtgaggcccaggatgtcaaagatgttgaccagaatttgatg
gatcgcctacagagagtgaataacactctgtccagccaaattagccgtttacagaatatc
cggaataccattgaagagactggaaacttggctgaacaagcgcgtgcccatgtagagaac
acagagcggttgattgaaatcgcatccagagaacttgagaaagcaaaagtcgctgctgcc
aatgtgtcagtcactcagccagaatctacaggggacccaaacaacatgactcttttggca
gaagaggctcgaaagcttgctgaacgtcataaacaggaagctgatgacattgttcgagtg
gcaaagacagccaatgatacgtcaactgaggcatacaacctgcttctgaggacactggca
ggagaaaatcaaacagcatttgagattgaagagcttaataggaagtatgaacaagcgaag
aacatctcacaggatctggaaaaacaagctgcccgagtacatgaggaggccaaaagggcc
ggtgacaaagctgtggagatctatgccagcgtggctcagctgagccctttggactctgag
acactggagaatgaagcaaataacataaagatggaagctgagaatctggaacaactgatt
gaccagaaattaaaagattatgaggacctcagagaagatatgagagggaaggaacttgaa
gtcaagaaccttctggagaaaggcaagactgaacagcagaccgcagaccaactcctagcc
cgagctgatgctgccaaggccctcgctgaagaagctgcaaagaagggacgggatacctta
caagaagctaatgacattctcaacaacctgaaagattttgataggcgtgtgaacgataac
aagacggccgcagaggaggcactaaggaagattcctgccatcaaccagaccatcactgaa
gccaatgaaaagaccagagaagcccagcaggccctgggcagtgctgcggcggatgccaca
gaggccaagaacaaggcccatgaggcggagaggatcgcgagcgctgtccaaaagaatgcc
accagcaccaaggcagaagctgaaagaacttttgcagaagttacagatctggataatgag
gtgaacaatatgttgaagcaactgcaggaagcagaaaaagagctaaagagaaaacaagat
gacgctgaccaggacatgatgatggcagggatggcttcacaggctgctcaagaagccgag
atcaatgccagaaaagccaaaaactctgttactagcctcctcagcattattaatgacctc
ttggagcagctggggcagctggatacagtggacctgaataagctaaacgagattgaaggc
accctaaacaaagccaaagatgaaatgaaggtcagcgatcttgataggaaagtgtctgac
ctggagaatgaagccaagaagcaggaggctgccatcatggactataaccgagatatcgag
gagatcatgaaggacattcgcaatctggaggacatcaggaagaccttaccatctggctgc
ttcaacaccccgtccattgaaaagccctag

KEGG   Homo sapiens (human): 3918Help
Entry
3918              CDS       T01001                                 

Gene name
LAMC2, B2T, BM600, CSF, EBR2, EBR2A, LAMB2T, LAMNB2
Definition
(RefSeq) laminin subunit gamma 2
  KO
K06246  laminin, gamma 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Disease
H00586  Epidermolysis bullosa, junctional
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3918 (LAMC2)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3918 (LAMC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3918 (LAMC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3918 (LAMC2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    3918 (LAMC2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3918 (LAMC2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    3918 (LAMC2)
   05145 Toxoplasmosis
    3918 (LAMC2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Laminin_EGF Laminin_B
Motif
Other DBs
NCBI-GeneID: 3918
NCBI-ProteinID: NP_005553
OMIM: 150292
HGNC: 6493
Ensembl: ENSG00000058085
Vega: OTTHUMG00000035520
Pharos: Q13753(Tbio)
UniProt: Q13753
LinkDB All DBs
Position
1q25.3
AA seq 1193 aa AA seqDB search
MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT
DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF
HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN
PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF
SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL
MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI
DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG
GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV
CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK
CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP
NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL
QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH
RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR
ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE
ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG
NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL
QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE
IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE
AQKVDTRAKNAGVTIQDTLNTLDGLLHLMDQPLSVDEEGLVLLEQKLSRAKTQINSQLRP
MMSELEERARQQRGHLHLLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ
NT seq 3582 nt NT seq  +upstreamnt  +downstreamnt
atgcctgcgctctggctgggctgctgcctctgcttctcgctcctcctgcccgcagcccgg
gccacctccaggagggaagtctgtgattgcaatgggaagtccaggcagtgtatctttgat
cgggaacttcacagacaaactggtaatggattccgctgcctcaactgcaatgacaacact
gatggcattcactgcgagaagtgcaagaatggcttttaccggcacagagaaagggaccgc
tgtttgccctgcaattgtaactccaaaggttctcttagtgctcgatgtgacaactccgga
cggtgcagctgtaaaccaggtgtgacaggagccagatgcgaccgatgtctgccaggcttc
cacatgctcacggatgcggggtgcacccaagaccagagactgctagactccaagtgtgac
tgtgacccagctggcatcgcagggccctgtgacgcgggccgctgtgtctgcaagccagct
gtcactggagaacgctgtgataggtgtcgatcaggttactataatctggatggggggaac
cctgagggctgtacccagtgtttctgctatgggcattcagccagctgccgcagctctgca
gaatacagtgtccataagatcacctctacctttcatcaagatgttgatggctggaaggct
gtccaacgaaatgggtctcctgcaaagctccaatggtcacagcgccatcaagatgtgttt
agctcagcccaacgactagaccctgtctattttgtggctcctgccaaatttcttgggaat
caacaggtgagctatggtcaaagcctgtcctttgactaccgtgtggacagaggaggcaga
cacccatctgcccatgatgtgattctggaaggtgctggtctacggatcacagctcccttg
atgccacttggcaagacactgccttgtgggctcaccaagacttacacattcaggttaaat
gagcatccaagcaataattggagcccccagctgagttactttgagtatcgaaggttactg
cggaatctcacagccctccgcatccgagctacatatggagaatacagtactgggtacatt
gacaatgtgaccctgatttcagcccgccctgtctctggagccccagcaccctgggttgaa
cagtgtatatgtcctgttgggtacaaggggcaattctgccaggattgtgcttctggctac
aagagagattcagcgagactggggccttttggcacctgtattccttgtaactgtcaaggg
ggaggggcctgtgatccagacacaggagattgttattcaggggatgagaatcctgacatt
gagtgtgctgactgcccaattggtttctacaacgatccgcacgacccccgcagctgcaag
ccatgtccctgtcataacgggttcagctgctcagtgatgccggagacggaggaggtggtg
tgcaataactgccctcccggggtcaccggtgcccgctgtgagctctgtgctgatggctac
tttggggacccctttggtgaacatggcccagtgaggccttgtcagccctgtcaatgcaac
aacaatgtggaccccagtgcctctgggaattgtgaccggctgacaggcaggtgtttgaag
tgtatccacaacacagccggcatctactgcgaccagtgcaaagcaggctacttcggggac
ccattggctcccaacccagcagacaagtgtcgagcttgcaactgtaaccccatgggctca
gagcctgtaggatgtcgaagtgatggcacctgtgtttgcaagccaggatttggtggcccc
aactgtgagcatggagcattcagctgtccagcttgctataatcaagtgaagattcagatg
gatcagtttatgcagcagcttcagagaatggaggccctgatttcaaaggctcagggtggt
gatggagtagtacctgatacagagctggaaggcaggatgcagcaggctgagcaggccctt
caggacattctgagagatgcccagatttcagaaggtgctagcagatcccttggtctccag
ttggccaaggtgaggagccaagagaacagctaccagagccgcctggatgacctcaagatg
actgtggaaagagttcgggctctgggaagtcagtaccagaaccgagttcgggatactcac
aggctcatcactcagatgcagctgagcctggcagaaagtgaagcttccttgggaaacact
aacattcctgcctcagaccactacgtggggccaaatggctttaaaagtctggctcaggag
gccacaagattagcagaaagccacgttgagtcagccagtaacatggagcaactgacaagg
gaaactgaggactattccaaacaagccctctcactggtgcgcaaggccctgcatgaagga
gtcggaagcggaagcggtagcccggacggtgctgtggtgcaagggcttgtggaaaaattg
gagaaaaccaagtccctggcccagcagttgacaagggaggccactcaagcggaaattgaa
gcagataggtcttatcagcacagtctccgcctcctggattcagtgtctcggcttcaggga
gtcagtgatcagtcctttcaggtggaagaagcaaagaggatcaaacaaaaagcggattca
ctctcaagcctggtaaccaggcatatggatgagttcaagcgtacacagaagaatctggga
aactggaaagaagaagcacagcagctcttacagaatggaaaaagtgggagagagaaatca
gatcagctgctttcccgtgccaatcttgctaaaagcagagcacaagaagcactgagtatg
ggcaatgccactttttatgaagttgagagcatccttaaaaacctcagagagtttgacctg
caggtggacaacagaaaagcagaagctgaagaagccatgaagagactctcctacatcagc
cagaaggtttcagatgccagtgacaagacccagcaagcagaaagagccctggggagcgct
gctgctgatgcacagagggcaaagaatggggccggggaggccctggaaatctccagtgag
attgaacaggagattgggagtctgaacttggaagccaatgtgacagcagatggagccttg
gccatggaaaagggactggcctctctgaagagtgagatgagggaagtggaaggagagctg
gaaaggaaggagctggagtttgacacgaatatggatgcagtacagatggtgattacagaa
gcccagaaggttgataccagagccaagaacgctggggttacaatccaagacacactcaac
acattagacggcctcctgcatctgatggaccagcctctcagtgtagatgaagaggggctg
gtcttactggagcagaagctttcccgagccaagacccagatcaacagccaactgcggccc
atgatgtcagagctggaagagagggcacgtcagcagaggggccacctccatttgctggag
acaagcatagatgggattctggctgatgtgaagaacttggagaacattagggacaacctg
cccccaggctgctacaatacccaggctcttgagcaacagtga

KEGG   Homo sapiens (human): 5649Help
Entry
5649              CDS       T01001                                 

Gene name
RELN, ETL7, LIS2, PRO1598, RL
Definition
(RefSeq) reelin
  KO
K06249  reelin [EC:3.4.21.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05165  Human papillomavirus infection
Disease
H00268  Lissencephaly
H00809  Familial epilepsy temporal lobe (ETL)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    5649 (RELN)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    5649 (RELN)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    5649 (RELN)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    5649 (RELN)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.-  
     5649 (RELN)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: BNR EGF_2 Reeler EGF_Tenascin EB
Motif
Other DBs
NCBI-GeneID: 5649
NCBI-ProteinID: NP_005036
OMIM: 600514
HGNC: 9957
Ensembl: ENSG00000189056
Vega: OTTHUMG00000157247
Pharos: P78509(Tbio)
UniProt: P78509
LinkDB All DBs
Position
7q22.1
AA seq 3460 aa AA seqDB search
MERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLH
IAGNPTYYVPGQEYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQF
GNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATATHRGQVIFKDALAQQLCEQ
GAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAV
TFCEPYGPRELITTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKI
RAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEACWALDNILIINSAHRQVVL
EDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQW
SEEFESQPTGWDVLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVM
GGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSLVSVVINPELQTPATKFCL
RQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRS
WSLLHTECLPEICAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILG
NMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEMASQTFPMFISESFGSSRL
SSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKS
VLSTCRAPDQPGEGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFR
WWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQSLGFYLGNVQPYCGHDWTL
CFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHMDNQVKLEYSTNHGLTW
HLVQEECLPSMPSCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQD
EWALDSIYIGQQCPNMCSGHGSCDHGICRCDQGYQGTECHPEAALPSTIMSDFENQNGWE
SDWQEVIGGEIVKPEQGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGES
ASCNKPDSREEGVLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWW
QPVFSGEDYDQWAVDDIIILSEKQKQIIPVINPTLPQNFYEKPAFDYPMNQMSVWLMLAN
EGMVKNETFCAATPSAMIFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSTAPVL
LQYSHDAGMSWFLVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLA
SSKTRFRWIQESSSQKNVPPFGLDGVYISEPCPSYCSGHGDCISGVCFCDLGYTAAQGTC
VSNVPNHNEMFDRFEGKLSPLWYKITGAQVGTGCGTLNDGKSLYFNGPGKREARTVPLDT
RNIRLVQFYIQIGSKTSGITCIKPRTRNEGLIVQYSNDNGILWHLLRELDFMSFLEPQII
SIDLPQDAKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSSQTGFQDKFDGSIDLQANW
YRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSNSH
SVQLQYSLNNGKDWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPR
TRFRWIQANYTVGADSWAIDNVVLASGCPWMCSGRGICDAGRCVCDRGFGGPYCVPVVPL
PSILKDDFNGNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTM
YVQFSLRFIAKSTPERSHSILLQFSISGGITWHLMDEFYFPQTTNILFINVPLPYTAQTN
ATRFRLWQPYNNGKKEEIWIVDDFIIDGNNVNNPVMLLDTFDFGPREDNWFFYPGGNIGL
YCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVR
LEFSRDFGATWHLLLPLCYHSSSHVSSLCSTEHHPSSTYYAGTMQGWRREVVHFGKLHLC
GSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCNGQGSCINGTKCICDPGYSGPTCK
ISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDL
SHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEI
PLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFTTLDSRKWLLHPG
GTKMPVCGSTGDALVFIEKASTRYVVSTDVAVNEDSFLQIDFAASCSVTDSCYAIELEYS
VDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPPYTRSQATRFRWHQ
PAPFDKQQTWAIDNVYIGDGCIDMCSGHGRCIQGNCVCDEQWGGLYCDDPETSLPTQLKD
NFNRAPSSQNWLTVNGGKLSTVCGAVASGMALHFSGGCSRLLVTVDLNLTNAEFIQFYFM
YGCLITPNNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRW
WQPRHDGLDQNDWAIDNVLISGSADQRTVMLDTFSSAPVPQHERSPADAGPVGRIAFDMF
MEDKTSVNEHWLFHDDCTVERFCDSPDGVMLCGSHDGREVYAVTHDLTPTEGWIMQFKIS
VGCKVSEKIAQNQIHVQYSTDFGVSWNYLVPQCLPADPKCSGSVSQPSVFFPTKGWKRIT
YPLPESLVGNPVRFRFYQKYSDMQWAIDNFYLGPGCLDNCRGHGDCLREQCICDPGYSGP
NCYLTHTLKTFLKERFDSEEIKPDLWMSLEGGSTCTECGILAEDTALYFGGSTVRQAVTQ
DLDLRGAKFLQYWGRIGSENNMTSCHRPICRKEGVLLDYSTDGGITWTLLHEMDYQKYIS
VRHDYILLPEDALTNTTRLRWWQPFVISNGIVVSGVERAQWALDNILIGGAEINPSQLVD
TFDDEGTSHEENWSFYPNAVRTAGFCGNPSFHLYWPNKKKDKTHNALSSRELIIQPGYMM
QFKIVVGCEATSCGDLHSVMLEYTKDARSDSWQLVQTQCLPSSSNSIGCSPFQFHEATIY
NSVNSSSWKRITIQLPDHVSSSATQFRWIQKGEETEKQSWAIDHVYIGEACPKLCSGHGY
CTTGAICICDESFQGDDCSVFSHDLPSYIKDNFESARVTEANWETIQGGVIGSGCGQLAP
YAHGDSLYFNGCQIRQAATKPLDLTRASKIMFVLQIGSMSQTDSCNSDLSGPHAVDKAVL
LQYSVNNGITWHVIAQHQPKDFTQAQRVSYNVPLEARMKGVLLRWWQPRHNGTGHDQWAL
DHVEVVLVSTRKQNYMMNFSRQHGLRHFYNRRRRSLRRYP
NT seq 10383 nt NT seq  +upstreamnt  +downstreamnt
atggagcgcagtggctgggcccggcagactttcctcctagcgctgttgctgggggcgacg
ctgagggcgcgcgcggcggctggctattacccccgcttttcgcccttctttttcctgtgc
acccaccacggggagctggaaggggatggggagcagggcgaggtgctcatttccctgcat
attgcgggcaaccccacctactacgttccgggacaagaataccatgtgacaatttcaaca
agcaccttttttgacggcttgctggtgacaggactatacacatctacaagtgttcaggca
tcacagagcattggaggttccagtgctttcggatttgggatcatgtctgaccaccagttt
ggtaaccagtttatgtgcagtgtggtagcctctcacgtgagtcacctgcccacaaccaac
ctcagtttcatctggattgctccacctgcgggcacaggctgtgtgaatttcatggctaca
gcaacacaccggggccaggttattttcaaagatgctttagcccagcagttgtgtgaacaa
ggagctccaacagatgtcactgtgcacccacatctagctgaaatacatagtgacagcatt
atcctgagagatgactttgactcctaccaccaactgcaattaaatccaaatatatgggtt
gaatgtaacaactgtgagactggagaacagtgtggcgcgattatgcatggcaatgccgtc
accttctgtgaaccatatggcccacgagaactgattaccacaggccttaatacaacaaca
gcttctgtcctccaattttccattgggtcaggttcatgtcgctttagttattcagacccc
agcatcatcgtgttatatgccaagaataactctgcggactggattcagctagagaaaatt
agagccccttccaatgtcagcacaatcatccatatcctctaccttcctgaggacgccaaa
ggggagaatgtccaatttcagtggaagcaggaaaatcttcgtgtaggtgaagtgtatgaa
gcctgctgggccttagataacatcttgatcatcaattcagctcacagacaagtcgtttta
gaagatagtctcgacccagtggacacaggcaactggcttttcttcccaggagctacagtt
aagcatagctgtcagtcagatgggaactccatttatttccatggaaatgaaggcagcgag
ttcaattttgccaccaccagggatgtagatctttccacagaagatattcaagagcaatgg
tcagaagaatttgagagccagcctacaggatgggatgtcttgggagctgtcattggtaca
gaatgtggaacgatagaatcaggcttatcaatggtcttcctcaaagatggagagaggaaa
ttatgcactccatccatggacactaccggttatgggaacctgaggttttactttgtgatg
ggaggaatttgtgaccctggaaattctcatgaaaatgacataatcctgtatgcaaaaatt
gaaggaagaaaagagcatataacactggataccctttcctattcctcatataaggttccg
tctttggtttctgtggtcatcaatcctgaacttcagactcctgctaccaaattttgtctc
aggcaaaagaaccatcaaggacataataggaatgtctgggctgtagactttttccatgtc
ttgcctgttctcccttctacaatgtctcacatgatacagttttccatcaatctgggatgt
ggaacgcatcagcctggtaacagtgtcagcttggaattttctaccaaccatgggcgctcc
tggtccctccttcacactgaatgcttacctgagatctgtgctggaccccacctcccccac
agcactgtctactcctctgaaaactacagtgggtggaaccgaataacaattccccttcct
aacgcagcactaacccggaacaccaggattcgctggagacaaacaggaccaatccttgga
aacatgtgggcaattgataatgtttatattggcccgtcatgtctcaaattctgttctggc
agaggacagtgcactagacatggttgcaagtgtgaccctggattttctggcccagcttgt
gagatggcatcccagacattcccaatgtttatttctgaaagctttggcagttccaggctc
tcctcttaccataacttttactctatccgtggtgctgaagtcagctttggttgtggtgtc
ttggccagtggtaaggccctggttttcaacaaagatgggcggcgtcagctaattacatct
ttccttgacagctcacaatccaggtttctccagttcacactgagactggggagcaaatct
gttctgagcacgtgcagagcccctgatcagcctggtgaaggagttttgttgcattattct
tatgataatgggataacttggaaactcctggagcattattcatatctcagctatcatgag
cccagaataatctccgtagaactaccaggtgatgcaaagcagtttggaattcagttcaga
tggtggcaaccgtatcattcttcccagagagaagatgtatgggctattgatgagattatc
atgacatctgtgcttttcaacagcattagtcttgactttaccaatcttgtggaggtcact
cagtctctgggattctaccttggaaatgttcagccatactgtggccacgactggaccctt
tgttttacaggagattctaaacttgcctcaagtatgcgctatgtggaaacacaatcaatg
cagataggagcatcctatatgattcagttcagtttggtgatgggatgtggccagaaatac
accccacacatggacaaccaggtgaagctggagtactcaaccaaccacggccttacctgg
cacctcgtccaagaagaatgccttccaagtatgccaagttgtcaggaatttacatcagca
agtatttaccatgccagtgagtttacacagtggaggagagtcatagtgcttcttccccag
aaaacttggtccagtgctacccgtttccgctggagccagagctattacacagctcaagac
gagtgggctttggacagcatttacattgggcagcagtgccccaacatgtgcagtgggcat
ggctcatgcgatcatggcatatgcaggtgtgaccaggggtaccaaggcactgaatgccac
ccagaagctgcccttccgtccacaattatgtcagattttgagaaccagaatggctgggag
tctgactggcaagaagttattgggggagaaattgtaaaaccagaacaagggtgtggtgtc
atctcttctggatcatctctgtacttcagcaaggctgggaaaagacagctggtgagttgg
gacctggatacttcttgggtggactttgtccagttctacatccagataggcggagagagt
gcttcatgcaacaagcctgacagcagagaggagggcgtcctccttcagtacagcaacaat
gggggcatccagtggcacctgctagcagagatgtacttttcagacttcagcaaacccaga
tttgtctatctggagcttccagctgctgccaagaccccttgcaccaggttccgctggtgg
cagcccgtgttctcaggggaggactatgaccagtgggcagtcgatgacatcatcattctg
tccgagaagcagaagcagatcatcccagttatcaatccaactttacctcagaacttttat
gagaagccagcttttgattaccctatgaatcagatgagtgtgtggttgatgttggctaat
gaaggaatggttaaaaatgaaaccttctgtgctgccacaccatcagcaatgatatttgga
aaatcagatggagatcgatttgcagtaactcgagatttgaccctgaaacctggatatgtg
ctacagttcaagctaaacataggttgtgccaatcaattcagcagtactgctccagttctt
cttcagtactctcatgatgctggtatgtcctggtttctggtgaaagaaggctgttacccg
gcttctgcaggcaaaggatgcgaaggaaactccagagaactaagtgagcccaccatgtat
cacacaggggactttgaagaatggacaagaatcaccattgttattccaaggtctcttgca
tccagcaagaccagattccgatggatccaggagagcagctcacagaaaaacgtgcctcca
tttggtttagatggagtgtacatatccgagccttgtcccagttactgcagtggccatggg
gactgcatttcaggagtgtgtttctgtgacctgggatatactgctgcacaaggaacctgt
gtgtcaaatgtccccaatcacaatgagatgttcgataggtttgaggggaagctcagccct
ctgtggtacaagataacaggtgcccaggttggaactggctgtggaacacttaacgatggc
aaatctctctacttcaatggccctgggaaaagggaagcccggacggtccctctggacacc
aggaatatcagacttgttcaattttatatacaaattggaagcaaaacttcaggcattacc
tgcatcaaaccaagaactagaaatgaagggcttattgttcagtattcaaatgacaatggg
atactctggcatttgcttcgagagttggacttcatgtccttcctggaaccacagatcatt
tccattgacctgccacaggacgcgaagacacctgcaacggcatttcgatggtggcaaccg
caacatgggaagcattcagcccagtgggctttggatgatgttcttataggaatgaatgac
agctctcaaactggatttcaagacaaatttgatggctctatagatttgcaagccaactgg
tatcgaatccaaggaggtcaagttgatattgactgtctctctatggatactgctctgata
ttcactgaaaacataggaaaacctcgttatgctgagacctgggattttcatgtgtcagca
tctacctttttgcagtttgaaatgagcatgggctgtagcaagcccttcagcaactcccac
agtgtacagctccagtattctctgaacaatggcaaggactggcatcttgtcaccgaagag
tgtgttcctccaaccattggctgtctgcattacacggaaagttcaatttacacctcggaa
agattccagaattggaagcggatcactgtctaccttccactctccaccatttctcccagg
acccggttcagatggattcaggccaactacactgtgggggctgattcctgggcgattgat
aatgttgtactggcctcagggtgcccttggatgtgctcaggacgagggatttgtgatgct
ggacgctgtgtgtgtgaccggggctttggtggaccctattgtgttcctgttgttcctctg
ccctcgattcttaaagacgatttcaatgggaatttacatcctgacctttggcctgaagtg
tatggtgcagagagggggaatctgaatggtgaaaccatcaaatctggaacatctctaatt
tttaaaggggaaggactaaggatgcttatttcaagagatctagattgtacaaatacaatg
tatgtccagttttcacttagatttatagcaaaaagtaccccagagagatctcactctatt
ctgttacaattctccatcagtggaggaatcacttggcacctgatggatgaattttacttt
cctcaaacaacgaatatacttttcatcaatgttcccttgccatacactgcccaaaccaat
gctacaagattcagactctggcaaccttataataacggtaagaaagaagaaatctggatt
gttgatgacttcattatcgatggaaataatgtaaacaaccctgtgatgctcttggataca
tttgattttgggcccagagaagacaattggtttttctatcctggtggtaacatcggtctt
tattgtccatattcttcaaagggggcacctgaagaagattcagctatggtgtttgtttca
aatgaagttggtgagcattccattaccacccgtgacctaaatgtgaatgagaacaccatc
atacaatttgagatcaacgttggctgttcgactgatagctcatccgcggatccagtgaga
ctggaattttcaagggacttcggggcgacctggcaccttctgctgcccctctgctaccac
agcagcagccacgtcagctctttatgctccaccgagcaccaccccagcagcacctactac
gcaggaaccatgcagggctggaggagggaggtcgtgcactttgggaagctgcacctttgt
ggatctgtccgtttcagatggtaccagggattttaccctgccggctctcagccagtgaca
tgggccattgataatgtctacatcggtccccagtgtgaggagatgtgtaatggacagggg
agctgtatcaatggaaccaaatgtatatgtgaccctggctactcaggtccaacctgtaaa
ataagcaccaaaaatcctgattttctcaaagatgatttcgaaggtcagctagaatctgat
agattcttattaatgagtggtgggaaaccatctcgaaagtgtggaatcctttctagtgga
aacaacctctttttcaatgaagatggcttgcgcatgttgatgacacgagacctggattta
tcacatgctagatttgtgcagttcttcatgagactgggatgtggtaaaggcgttcctgac
cccaggagtcaacccgtgctcctacagtattctctcaacggtggcctctcgtggagtctt
cttcaggagttccttttcagcaattccagcaatgtgggcaggtacattgccctggagata
cccttgaaagcccgttctggttctactcgccttcgctggtggcaaccgtctgagaatggg
cacttctacagcccctgggttatcgatcagattcttattggaggaaatatttctggtaat
acggtcttggaagatgatttcacaacccttgatagtaggaaatggctgcttcacccagga
ggcaccaagatgcccgtgtgtggctctactggtgatgccctggtcttcattgaaaaggcc
agcacccgttacgtggtcagcacagacgttgccgtgaatgaggattccttcctacagata
gacttcgctgcctcctgctcagtcacagactcttgttatgcgattgaattggaatactca
gtagatcttggattgtcatggcacccattggtaagggactgtctgcctaccaatgtggaa
tgcagtcgctatcatctgcaacggatcctggtgtcagacactttcaacaagtggactaga
atcactctgcctctccctccttataccaggtcccaagccactcgtttccgttggcatcaa
ccagctccttttgacaagcagcagacatgggcaatagataatgtctatatcggggatggc
tgcatagacatgtgcagtggccatgggagatgcatccagggaaactgcgtctgtgatgaa
cagtggggtggcctgtactgtgatgaccccgagacctctcttccaacccaactcaaagac
aacttcaatcgagctccatccagtcagaactggctgactgtgaacggagggaaattgagt
acagtgtgtggagccgtggcgtcgggaatggctctccatttcagtgggggttgtagtcga
ttattagtcactgtggatctaaacctcactaatgctgagttcatccaattttacttcatg
tatgggtgcctgattacaccaaacaaccgtaaccaaggtgttctcttggaatattctgtc
aatggaggcattacctggaacctgctcatggagattttctatgaccagtacagtaagccc
ggatttgtgaatatccttctccctcctgatgctaaagagattgccactcgcttccgctgg
tggcagccaagacatgacggcctggatcagaacgactgggccattgacaatgtcctcatc
tcaggctctgctgaccaaaggaccgttatgctggacaccttcagcagcgccccagtaccc
cagcatgagcgctcccctgcagatgccggccctgtcgggaggatcgcctttgacatgttt
atggaagacaaaacttcagtgaatgagcactggctattccatgatgattgtacagtagaa
agattctgtgactcccctgatggtgtgatgctctgtggcagtcatgatggacgggaggtg
tatgcagtgacccatgacctgactcccactgaaggctggattatgcaattcaagatctca
gttggatgtaaggtgtctgaaaaaattgcccagaatcaaattcatgtgcagtattctact
gacttcggtgtgagttggaattatctggtccctcagtgcttgcctgctgacccaaaatgc
tctggaagtgtttctcagccatctgtattctttccaactaaagggtggaaaaggatcacc
tacccacttcctgaaagcttagtgggaaatccggtaaggtttaggttctatcagaagtac
tcagacatgcagtgggcaatcgataatttctacctgggccctggatgcttggacaactgc
aggggccatggagattgcttaagggaacagtgcatctgtgatccgggatactcagggcca
aactgctacttgacccacactctgaagactttcctgaaggaacgctttgacagtgaagaa
atcaaacctgacttatggatgtccttagaaggtggaagtacttgcactgagtgtggaatt
cttgccgaggacactgcactctattttgggggatccactgtgagacaagcggttacacaa
gatttggatcttcgaggtgcaaagttcctgcaatactgggggcgcatcggtagtgagaac
aacatgacctcttgccatcgtcccatctgccggaaggaaggcgtgctgttggactactct
accgatggaggaattacctggactttgctccatgagatggattaccagaaatacatttct
gttagacacgactacatacttcttcctgaagatgccctcaccaacacaactcgacttcgc
tggtggcagccttttgtgatcagcaatggaattgtggtctctggggtggagcgtgctcag
tgggcactggacaacattttgattggtggagcagaaatcaatcccagccaattggtggac
acttttgatgatgaaggcacttcccatgaagaaaactggagtttttaccctaatgctgta
aggacagcaggattttgtggcaatccatcctttcacctctattggccaaataaaaagaag
gacaagactcacaatgctctctcctcccgagaactcattatacagccaggatacatgatg
cagtttaaaattgtggtgggttgtgaagccacttcttgtggtgaccttcattccgtaatg
ctggaatacactaaggatgcaagatcggattcctggcagctcgtacagacccagtgcctt
ccttcctcttctaacagcattggctgctcccctttccagttccatgaagccaccatctac
aactctgtcaacagctcaagctggaaaagaatcaccatccagctgcctgaccatgtctcc
tctagtgcaacacagttccgctggatccagaagggagaagaaactgagaagcaaagctgg
gcaattgaccacgtgtacattggagaggcttgccccaagctctgcagcgggcacggatac
tgcacgaccggtgccatctgcatctgcgacgagagcttccaaggtgatgactgctctgtt
ttcagtcacgaccttcccagttatattaaagataattttgagtccgcaagagtcaccgag
gcaaactgggagaccattcaaggtggagtcataggaagtggctgtgggcagctggccccc
tacgcccatggagactcactgtactttaatggctgtcagatcaggcaagcagctaccaag
cctctggatctcactcgagcaagcaaaatcatgtttgttttgcaaattgggagcatgtcg
cagacggacagctgcaacagtgacctgagtggcccccacgctgtggacaaggcagtgctg
ctgcaatacagcgtcaacaacgggatcacctggcatgtcatcgcccagcaccagccaaag
gacttcacacaagctcagagagtgtcttacaatgtccccctggaggcacggatgaaagga
gtcttactgcgctggtggcaaccacgccacaatggaacaggtcatgatcaatgggctttg
gaccatgtggaggtcgtcctagtaagcactcgcaaacaaaattacatgatgaatttttca
cgacaacatgggctcagacatttctacaacagaagacgaaggtcacttaggcgataccca
tga

KEGG   Homo sapiens (human): 63923Help
Entry
63923             CDS       T01001                                 

Gene name
TNN, TN-W
Definition
(RefSeq) tenascin N
  KO
K06252  tenascin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05165  Human papillomavirus infection
hsa05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    63923 (TNN)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    63923 (TNN)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    63923 (TNN)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    63923 (TNN)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    63923 (TNN)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    63923 (TNN)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   63923 (TNN)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: fn3 Fibrinogen_C DUF4998 Pur_ac_phosph_N EGF_2 DUF4959 EGF_Tenascin
Motif
Other DBs
NCBI-GeneID: 63923
NCBI-ProteinID: NP_071376
OMIM: 617472
HGNC: 22942
Ensembl: ENSG00000120332
Vega: OTTHUMG00000034882
Pharos: Q9UQP3(Tbio)
UniProt: Q9UQP3 B3KXB6
LinkDB All DBs
Position
1q25.1
AA seq 1299 aa AA seqDB search
MSLQEMFRFPMGLLLGSVLLVASAPATLEPPGCSNKEQQVTVSHTYKIDVPKSALVQVDA
DPQPLSDDGASLLALGEAREEQNIIFRHNIRLQTPQKDCELAGSVQDLLARVKKLEEEMV
EMKEQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGR
CVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGH
GFCDTGECYCEEGFTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGK
ELSGKQIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVT
DETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYK
ITVVPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA
DGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTD
RVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHV
WAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGE
TREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVT
ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ
KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE
VPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENM
ATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQ
ESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLG
REDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAA
SGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEF
WLGLDKLHNLTTGTPARYEVRVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGD
ALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPW
KGHEFSIPYVELKIRPHGYSREPVLGRKKRTLRGRLRTF
NT seq 3900 nt NT seq  +upstreamnt  +downstreamnt
atgagtctccaggagatgttccgcttccctatggggctcctgcttggctctgtgctcctg
gtggcttcggccccagccactctggagcctcccggctgcagcaacaaggagcaacaggtc
actgtcagccacacctacaagatcgatgtgcccaagtctgccttggttcaggttgacgct
gaccctcagcccctcagtgacgatggggcttcgctcttggccctgggggaggccagggag
gaacagaacatcatcttcaggcacaacatccgccttcagacgccacagaaggactgcgag
ttggcaggcagtgtccaggacctcctggcccgggtgaagaagctggaggaagagatggtg
gagatgaaggaacagtgtagtgcccagcgctgctgccagggagtcactgatctaagccgc
cactgcagcggccacgggaccttctccctggagacctgcagctgccactgcgaagagggc
agggagggccccgcctgcgagcggctggcctgccccggggcgtgcagcggccacgggcgt
tgcgtggacgggcgctgcctgtgccatgagccctacgtgggtgccgactgcggctacccg
gcctgccctgagaactgcagcggacacggcgagtgcgtgcgcggcgtgtgccagtgccac
gaagacttcatgtcggaggactgcagcgagaagcgctgtcccggcgactgcagcggccac
ggcttctgtgacacgggcgagtgctactgcgaggagggcttcacaggcctggactgtgcc
caggtggtcaccccacagggcctgcagctgctcaagaacacggaggattctctgctggtg
agctgggagccctccagccaggtggatcactacctcctcagctactaccccctggggaag
gagctctctgggaagcagatccaagtgcccaaggagcagcacagctatgagattcttggt
ttgctgcctggaaccaagtacatagtcaccctgcgtaacgtcaagaatgaagtttctagc
agcccacagcatctacttgccaccacagaccttgctgtgcttggcactgcctgggtgaca
gatgagactgagaactcccttgacgtggagtgggaaaacccctcaactgaggtggactac
tacaagctgcgatatggccccatgacaggacaggaggtagctgaggtcactgtgcccaag
agcagtgaccccaagagccgatatgacatcactggtctgcacccggggactgagtataag
atcacggtggtgcccatgagaggagagctggagggcaagccgatcctcctgaatggcagg
acagaaattgacagtccaaccaatgttgtcactgatcgagtgactgaagacacagcaact
gtctcctgggacccagtgcaggctgtcatagacaagtatgtagtgcgctacacttctgct
gatggggacaccaaggaaatggcagtgcacaaggatgagagcagcactgtcctgacgggc
ctgaagccaggagaggcatacaaggtctacgtgtgggctgaaaggggcaaccaggggagc
aagaaagctgacaccaatgccctcacagaaattgacagcccagcaaacctggtgactgac
cgggtgactgagaataccgccaccatctcctgggacccggtacaggccaccattgacaag
tacgtggtgcgctacacctctgctgacgaccaagagaccagagaggttctggtggggaag
gagcagagcagcactgtcctgacaggcctgaggccaggtgtggagtacacagtgcatgtc
tgggcccagaagggggaccgagagagcaagaaggctgacaccaacgccccgacagatatt
gacagccccaaaaacctggtgactgaccgggtgacagagaatatggccacggtctcctgg
gacccggtgcaggccgccattgacaagtacgtggtgcgctacacctctgctggtggagag
accagggaggttccggtggggaaggagcagagcagcacagtcctgacaggcctgagaccg
ggtatggagtacatggtgcacgtgtgggcccagaagggggaccaggagagcaagaaggcc
gacaccaaggcccagacagacattgacagcccccaaaacctggtgaccgaccgggtgaca
gagaatatggccactgtctcctgggacccggtgcgggccaccattgacaggtatgtggtg
cgctacacctctgccaaggacggagagaccagggaggttccggtggggaaggagcagagt
agcactgtcctgacgggcctgaggccgggtgtggagtacacggtgcacgtgtgggcccag
aagggggcccaggagagcaagaaggctgacaccaaggcccagacagacattgacagcccc
caaaacctggtcactgactgggtgacagagaatacagccactgtctcctgggacccggtg
caggccaccattgacaggtatgtggtgcactacacgtctgccaacggagagaccagggag
gttccagtggggaaggagcagagcagcactgtcctgacgggcctgaggccgggcatggag
tacacggtgcacgtgtgggcccagaaggggaaccaggagagcaagaaggctgacaccaag
gcccagacagaaattgacggccccaaaaacctagtgactgactgggtgacggagaatatg
gccactgtctcctgggacccggttcaggccaccattgacaagtacatggtgcgctacacc
tctgctgacggagagaccagggaggttccggtggggaaggagcacagcagcactgtcctg
acgggcctgagaccaggcatggagtacatggtgcacgtgtgggcccagaagggggcccag
gagagcaagaaggctgacaccaaggcccagacagaactcgaccctcccagaaaccttcgt
ccatctgctgtaacgcagtctggtggcatattgacctggacgcccccctctgctcagatc
cacggctacattctgacttaccagttcccagatggcacagttaaggagatgcagctggga
cgggaagaccagaggtttgcgttgcaaggccttgagcaaggcgccacctaccctgtctcc
cttgttgcctttaagggtggtcgccggagcagaaatgtatccaccaccctctccacagtt
ggtgcccgtttcccacacccttcggactgcagtcaggttcagcagaacagcaatgccgcc
agtggtctgtacaccatctacctgcatggcgatgccagccggcccctgcaggtgtactgt
gacatggaaacggacggaggtggctggattgtcttccagaggcggaacactgggcagctg
gatttcttcaagcgatggaggagctatgtggaaggctttggggaccccatgaaggagttc
tggcttggacttgacaagctacacaacctcaccaccggcactccagcgcggtatgaggtg
agagtggatttacagactgccaatgaatctgcctatgctatatatgatttcttccaagtg
gcctccagcaaggagcggtataagctgacagttgggaaatacagaggcacggcaggggat
gctcttacttaccacaatggatggaagtttacaacttttgacagagacaatgatatcgca
ctcagcaactgtgccctgacacatcatggtggctggtggtataagaactgccacttggcc
aaccctaatggcagatatggggagaccaagcacagtgagggggtgaactgggagccttgg
aaaggacatgaattctccattccttacgtggagttgaaaatccgccctcatggctacagc
agggagcctgtcctgggcagaaagaagcggacgctgagaggaaggctgcgaacgttctga

KEGG   Homo sapiens (human): 6696Help
Entry
6696              CDS       T01001                                 

Gene name
SPP1, BNSP, BSPI, ETA-1, OPN
Definition
(RefSeq) secreted phosphoprotein 1
  KO
K06250  secreted phosphoprotein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04620  Toll-like receptor signaling pathway
hsa05165  Human papillomavirus infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    6696 (SPP1)
   04151 PI3K-Akt signaling pathway
    6696 (SPP1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    6696 (SPP1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    6696 (SPP1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    6696 (SPP1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    6696 (SPP1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Osteopontin
Motif
Other DBs
NCBI-GeneID: 6696
NCBI-ProteinID: NP_001035147
OMIM: 166490
HGNC: 11255
Ensembl: ENSG00000118785
Vega: OTTHUMG00000130599
Pharos: P10451(Tbio)
UniProt: P10451 A0A024RDE2
LinkDB All DBs
Position
4q22.1
AA seq 314 aa AA seqDB search
MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
RISHELDSASSEVN
NT seq 945 nt NT seq  +upstreamnt  +downstreamnt
atgagaattgcagtgatttgcttttgcctcctaggcatcacctgtgccataccagttaaa
caggctgattctggaagttctgaggaaaagcagctttacaacaaatacccagatgctgtg
gccacatggctaaaccctgacccatctcagaagcagaatctcctagccccacagaatgct
gtgtcctctgaagaaaccaatgactttaaacaagagacccttccaagtaagtccaacgaa
agccatgaccacatggatgatatggatgatgaagatgatgatgaccatgtggacagccag
gactccattgactcgaacgactctgatgatgtagatgacactgatgattctcaccagtct
gatgagtctcaccattctgatgaatctgatgaactggtcactgattttcccacggacctg
ccagcaaccgaagttttcactccagttgtccccacagtagacacatatgatggccgaggt
gatagtgtggtttatggactgaggtcaaaatctaagaagtttcgcagacctgacatccag
taccctgatgctacagacgaggacatcacctcacacatggaaagcgaggagttgaatggt
gcatacaaggccatccccgttgcccaggacctgaacgcgccttctgattgggacagccgt
gggaaggacagttatgaaacgagtcagctggatgaccagagtgctgaaacccacagccac
aagcagtccagattatataagcggaaagccaatgatgagagcaatgagcattccgatgtg
attgatagtcaggaactttccaaagtcagccgtgaattccacagccatgaatttcacagc
catgaagatatgctggttgtagaccccaaaagtaaggaagaagataaacacctgaaattt
cgtatttctcatgaattagatagtgcatcttctgaggtcaattaa

KEGG   Homo sapiens (human): 7057Help
Entry
7057              CDS       T01001                                 

Gene name
THBS1, THBS, THBS-1, TSP, TSP-1, TSP1
Definition
(RefSeq) thrombospondin 1
  KO
K16857  thrombospondin 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04015  Rap1 signaling pathway
hsa04115  p53 signaling pathway
hsa04145  Phagosome
hsa04151  PI3K-Akt signaling pathway
hsa04350  TGF-beta signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05144  Malaria
hsa05165  Human papillomavirus infection
hsa05205  Proteoglycans in cancer
hsa05206  MicroRNAs in cancer
hsa05219  Bladder cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    7057 (THBS1)
   04350 TGF-beta signaling pathway
    7057 (THBS1)
   04151 PI3K-Akt signaling pathway
    7057 (THBS1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    7057 (THBS1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    7057 (THBS1)
  09143 Cell growth and death
   04115 p53 signaling pathway
    7057 (THBS1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    7057 (THBS1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    7057 (THBS1)
   05205 Proteoglycans in cancer
    7057 (THBS1)
  09162 Cancer: specific types
   05219 Bladder cancer
    7057 (THBS1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    7057 (THBS1)
  09174 Infectious disease: parasitic
   05144 Malaria
    7057 (THBS1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    7057 (THBS1)
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    7057 (THBS1)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Phagocytosis
   Opsonins
    7057 (THBS1)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   7057 (THBS1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: TSP_C TSP_3 TSP_1 VWC EGF_3 EGF_CA Laminin_G_3 cEGF Laminin_G_2 EGF Laminin_G_1
Motif
Other DBs
NCBI-GeneID: 7057
NCBI-ProteinID: NP_003237
OMIM: 188060
HGNC: 11785
Ensembl: ENSG00000137801
Vega: OTTHUMG00000133665
Pharos: P07996(Tbio)
UniProt: P07996
LinkDB All DBs
Structure
PDB: 

Position
15q14
AA seq 1170 aa AA seqDB search
MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR
IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVV
SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD
VPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLL
TLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK
VTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSN
ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQT
RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARE
TKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQI
CNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACF
NHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKN
AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPN
LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN
HNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEH
NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN
DGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRF
QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD
DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL
WHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYD
KTYAGGRLGLFVFSQEMVFFSDLKYECRDP
NT seq 3513 nt NT seq  +upstreamnt  +downstreamnt
atggggctggcctggggactaggcgtcctgttcctgatgcatgtgtgtggcaccaaccgc
attccagagtctggcggagacaacagcgtgtttgacatctttgaactcaccggggccgcc
cgcaaggggtctgggcgccgactggtgaagggccccgacccttccagcccagctttccgc
atcgaggatgccaacctgatcccccctgtgcctgatgacaagttccaagacctggtggat
gctgtgcgggcagaaaagggtttcctccttctggcatccctgaggcagatgaagaagacc
cggggcacgctgctggccctggagcggaaagaccactctggccaggtcttcagcgtggtg
tccaatggcaaggcgggcaccctggacctcagcctgaccgtccaaggaaagcagcacgtg
gtgtctgtggaagaagctctcctggcaaccggccagtggaagagcatcaccctgtttgtg
caggaagacagggcccagctgtacatcgactgtgaaaagatggagaatgctgagttggac
gtccccatccaaagcgtcttcaccagagacctggccagcatcgccagactccgcatcgca
aaggggggcgtcaatgacaatttccagggggtgctgcagaatgtgaggtttgtctttgga
accacaccagaagacatcctcaggaacaaaggctgctccagctctaccagtgtcctcctc
acccttgacaacaacgtggtgaatggttccagccctgccatccgcactaactacattggc
cacaagacaaaggacttgcaagccatctgcggcatctcctgtgatgagctgtccagcatg
gtcctggaactcaggggcctgcgcaccattgtgaccacgctgcaggacagcatccgcaaa
gtgactgaagagaacaaagagttggccaatgagctgaggcggcctcccctatgctatcac
aacggagttcagtacagaaataacgaggaatggactgttgatagctgcactgagtgtcac
tgtcagaactcagttaccatctgcaaaaaggtgtcctgccccatcatgccctgctccaat
gccacagttcctgatggagaatgctgtcctcgctgttggcccagcgactctgcggacgat
ggctggtctccatggtccgagtggacctcctgttctacgagctgtggcaatggaattcag
cagcgcggccgctcctgcgatagcctcaacaaccgatgtgagggctcctcggtccagaca
cggacctgccacattcaggagtgtgacaagagatttaaacaggatggtggctggagccac
tggtccccgtggtcatcttgttctgtgacatgtggtgatggtgtgatcacaaggatccgg
ctctgcaactctcccagcccccagatgaacgggaaaccctgtgaaggcgaagcgcgggag
accaaagcctgcaagaaagacgcctgccccatcaatggaggctggggtccttggtcacca
tgggacatctgttctgtcacctgtggaggaggggtacagaaacgtagtcgtctctgcaac
aaccccacaccccagtttggaggcaaggactgcgttggtgatgtaacagaaaaccagatc
tgcaacaagcaggactgtccaattgatggatgcctgtccaatccctgctttgccggcgtg
aagtgtactagctaccctgatggcagctggaaatgtggtgcttgtccccctggttacagt
ggaaatggcatccagtgcacagatgttgatgagtgcaaagaagtgcctgatgcctgcttc
aaccacaatggagagcaccggtgtgagaacacggaccccggctacaactgcctgccctgc
cccccacgcttcaccggctcacagcccttcggccagggtgtcgaacatgccacggccaac
aaacaggtgtgcaagccccgtaacccctgcacggatgggacccacgactgcaacaagaac
gccaagtgcaactacctgggccactatagcgaccccatgtaccgctgcgagtgcaagcct
ggctacgctggcaatggcatcatctgcggggaggacacagacctggatggctggcccaat
gagaacctggtgtgcgtggccaatgcgacttaccactgcaaaaaggataattgccccaac
cttcccaactcagggcaggaagactatgacaaggatggaattggtgatgcctgtgatgat
gacgatgacaatgataaaattccagatgacagggacaactgtccattccattacaaccca
gctcagtatgactatgacagagatgatgtgggagaccgctgtgacaactgtccctacaac
cacaacccagatcaggcagacacagacaacaatggggaaggagacgcctgtgctgcagac
attgatggagacggtatcctcaatgaacgggacaactgccagtacgtctacaatgtggac
cagagagacactgatatggatggggttggagatcagtgtgacaattgccccttggaacac
aatccggatcagctggactctgactcagaccgcattggagatacctgtgacaacaatcag
gatattgatgaagatggccaccagaacaatctggacaactgtccctatgtgcccaatgcc
aaccaggctgaccatgacaaagatggcaagggagatgcctgtgaccacgatgatgacaac
gatggcattcctgatgacaaggacaactgcagactcgtgcccaatcccgaccagaaggac
tctgacggcgatggtcgaggtgatgcctgcaaagatgattttgaccatgacagtgtgcca
gacatcgatgacatctgtcctgagaatgttgacatcagtgagaccgatttccgccgattc
cagatgattcctctggaccccaaagggacatcccaaaatgaccctaactgggttgtacgc
catcagggtaaagaactcgtccagactgtcaactgtgatcctggactcgctgtaggttat
gatgagtttaatgctgtggacttcagtggcaccttcttcatcaacaccgaaagggacgat
gactatgctggatttgtctttggctaccagtccagcagccgcttttatgttgtgatgtgg
aagcaagtcacccagtcctactgggacaccaaccccacgagggctcagggatactcgggc
ctttctgtgaaagttgtaaactccaccacagggcctggcgagcacctgcggaacgccctg
tggcacacaggaaacacccctggccaggtgcgcaccctgtggcatgaccctcgtcacata
ggctggaaagatttcaccgcctacagatggcgtctcagccacaggccaaagacgggtttc
attagagtggtgatgtatgaagggaagaaaatcatggctgactcaggacccatctatgat
aaaacctatgctggtggtagactagggttgtttgtcttctctcaagaaatggtgttcttc
tctgacctgaaatacgaatgtagagatccctaa

KEGG   Homo sapiens (human): 7058Help
Entry
7058              CDS       T01001                                 

Gene name
THBS2, TSP2
Definition
(RefSeq) thrombospondin 2
  KO
K04659  thrombospondin 2/3/4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05144  Malaria
hsa05165  Human papillomavirus infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    7058 (THBS2)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    7058 (THBS2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    7058 (THBS2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    7058 (THBS2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    7058 (THBS2)
  09174 Infectious disease: parasitic
   05144 Malaria
    7058 (THBS2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    7058 (THBS2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    7058 (THBS2)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    7058 (THBS2)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Phagocytosis
   Opsonins
    7058 (THBS2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   7058 (THBS2)
  Exosomal proteins of colorectal cancer cells
   7058 (THBS2)
  Exosomal proteins of bladder cancer cells
   7058 (THBS2)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   7058 (THBS2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: TSP_C TSP_3 TSP_1 VWC EGF_3 EGF_CA EGF cEGF Laminin_G_2
Motif
Other DBs
NCBI-GeneID: 7058
NCBI-ProteinID: NP_003238
OMIM: 188061
HGNC: 11786
Ensembl: ENSG00000186340
Vega: OTTHUMG00000045408
Pharos: P35442(Tbio)
UniProt: P35442
LinkDB All DBs
Structure
PDB: 

Position
6q27
AA seq 1172 aa AA seqDB search
MVWRLVLLALWVWPSTQAGHQDKDTTFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRF
DYIPPVNADDLSKITKIMRQKEGFFLTAQLKQDGKSRGTLLALEGPGLSQRQFEIVSNGP
ADTLDLTYWIDGTRHVVSLEDVGLADSQWKNVTVQVAGETYSLHVGCDLIDSFALDEPFY
EHLQAEKSRMYVAKGSARESHFRGLLQNVHLVFENSVEDILSKKGCQQGQGAEINAISEN
TETLRLGPHVTTEYVGPSSERRPEVCERSCEELGNMVQELSGLHVLVNQLSENLKRVSND
NQFLWELIGGPPKTRNMSACWQDGRFFAENETWVVDSCTTCTCKKFKTICHQITCPPATC
ASPSFVEGECCPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDVTSNTCLGPSI
QTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSG
RETKACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQER
QMCNKRSCPVDGCLSNPCFPGAQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDI
CFSTSKVPRCVNTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCKDKTHNCH
KHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNLNLVCATNATYHCIKDNC
PHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQLLFNPRQADYDKDEVGDRCDNCP
YVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPL
VHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNANQADHDRDGQGDACDPDD
DNDGVPDDRDNCRLVFNPDQEDLDGDGRGDICKDDFDNDNIPDIDDVCPENNAISETDFR
NFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDR
DDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRN
ALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPI
YDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI
NT seq 3519 nt NT seq  +upstreamnt  +downstreamnt
atggtctggaggctggtcctgctggctctgtgggtgtggcccagcacgcaagctggtcac
caggacaaagacacgaccttcgaccttttcagtatcagcaacatcaaccgcaagaccatt
ggcgccaagcagttccgcgggcccgaccccggcgtgccggcttaccgcttcgtgcgcttt
gactacatcccaccggtgaacgcagatgacctcagcaagatcaccaagatcatgcggcag
aaggagggcttcttcctcacggcccagctcaagcaggacggcaagtccaggggcacgctg
ttggctctggagggccccggtctctcccagaggcagttcgagatcgtctccaacggcccc
gcggacacgctggatctcacctactggattgacggcacccggcatgtggtctccctggag
gacgtcggcctggctgactcgcagtggaagaacgtcaccgtgcaggtggctggcgagacc
tacagcttgcacgtgggctgcgacctcatagacagcttcgctctggacgagcccttctac
gagcacctgcaggcggaaaagagccggatgtacgtggccaaaggctctgccagagagagt
cacttcaggggtttgcttcagaacgtccacctagtgtttgaaaactctgtggaagatatt
ctaagcaagaagggttgccagcaaggccagggagctgagatcaacgccatcagtgagaac
acagagacgctgcgcctgggtccgcatgtcaccaccgagtacgtgggccccagctcggag
aggaggcccgaggtgtgcgaacgctcgtgcgaggagctgggaaacatggtccaggagctc
tcggggctccacgtcctcgtgaaccagctcagcgagaacctcaagagagtgtcgaatgat
aaccagtttctctgggagctcattggtggccctcctaagacaaggaacatgtcagcttgc
tggcaggatggccggttctttgcggaaaatgaaacgtgggtggtggacagctgcaccacg
tgtacctgcaagaaatttaaaaccatttgccaccaaatcacctgcccgcctgcaacctgc
gccagtccatcctttgtggaaggcgaatgctgcccttcctgcctccactcggtggacggt
gaggagggctggtctccgtgggcagagtggacccagtgctccgtgacgtgtggctctggg
acccagcagagaggccggtcctgtgacgtcaccagcaacacctgcttggggccctccatc
cagacacgggcttgcagtctgagcaagtgtgacacccgcatccggcaggacggcggctgg
agccactggtcaccttggtcttcatgctctgtgacctgtggagttggcaatatcacacgc
atccgtctctgcaactccccagtgccccagatggggggcaagaattgcaaagggagtggc
cgggagaccaaagcctgccagggcgccccatgcccaatcgatggccgctggagcccctgg
tccccgtggtcggcctgcactgtcacctgtgccggtgggatccgggagcgcacccgggtc
tgcaacagccctgagcctcagtacggagggaaggcctgcgtgggggatgtgcaggagcgt
cagatgtgcaacaagaggagctgccccgtggatggctgtttatccaacccctgcttcccg
ggagcccagtgcagcagcttccccgatgggtcctggtcatgcggctcctgccctgtgggc
ttcttgggcaatggcacccactgtgaggacctggacgagtgtgccctggtccccgacatc
tgcttctccaccagcaaggtgcctcgctgtgtcaacactcagcctggcttccactgcctg
ccctgcccgccccgatacagagggaaccagcccgtcggggtcggcctggaagcagccaag
acggaaaagcaagtgtgtgagcccgaaaacccatgcaaggacaagacacacaactgccac
aagcacgcggagtgcatctacctgggccacttcagcgaccccatgtacaagtgcgagtgc
cagacaggctacgcgggcgacgggctcatctgcggggaggactcggacctggacggctgg
cccaacctcaatctggtctgcgccaccaacgccacctaccactgcatcaaggataactgc
ccccatctgccaaattctgggcaggaagactttgacaaggacgggattggcgatgcctgt
gatgatgacgatgacaatgacggtgtgaccgatgagaaggacaactgccagctcctcttc
aatccccgccaggctgactatgacaaggatgaggttggggaccgctgtgacaactgccct
tacgtgcacaaccctgcccagatcgacacagacaacaatggagagggtgacgcctgctcc
gtggacattgatggggacgatgtcttcaatgaacgagacaattgtccctacgtctacaac
actgaccagagggacacggatggtgacggtgtgggggatcactgtgacaactgccccctg
gtgcacaaccctgaccagaccgacgtggacaatgaccttgttggggaccagtgtgacaac
aacgaggacatagatgacgacggccaccagaacaaccaggacaactgcccctacatctcc
aacgccaaccaggctgaccatgacagagacggccagggcgacgcctgtgaccctgatgat
gacaacgatggcgtccccgatgacagggacaactgccggcttgtgttcaacccagaccag
gaggacttggacggtgatggacggggtgatatttgtaaagatgattttgacaatgacaac
atcccagatattgatgatgtgtgtcctgaaaacaatgccatcagtgagacagacttcagg
aacttccagatggtccccttggatcccaaagggaccacccaaattgatcccaactgggtc
attcgccatcaaggcaaggagctggttcagacagccaactcggaccccggcatcgctgta
ggttttgacgagtttgggtctgtggacttcagtggcacattctacgtaaacactgaccgg
gacgacgactatgccggcttcgtctttggttaccagtcaagcagccgcttctatgtggtg
atgtggaagcaggtgacgcagacctactgggaggaccagcccacgcgggcctatggctac
tccggcgtgtccctcaaggtggtgaactccaccacggggacgggcgagcacctgaggaac
gcgctgtggcacacggggaacacgccggggcaggtgcgaaccttatggcacgaccccagg
aacattggctggaaggactacacggcctataggtggcacctgactcacaggcccaagact
ggctacatcagagtcttagtgcatgaaggaaaacaggtcatggcagactcaggacctatc
tatgaccaaacctacgctggcgggcggctgggtctatttgtcttctctcaagaaatggtc
tatttctcagacctcaagtacgaatgcagagatatttaa

KEGG   Homo sapiens (human): 7059Help
Entry
7059              CDS       T01001                                 

Gene name
THBS3, TSP3
Definition
(RefSeq) thrombospondin 3
  KO
K04659  thrombospondin 2/3/4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05144  Malaria
hsa05165  Human papillomavirus infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    7059 (THBS3)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    7059 (THBS3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    7059 (THBS3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    7059 (THBS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    7059 (THBS3)
  09174 Infectious disease: parasitic
   05144 Malaria
    7059 (THBS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    7059 (THBS3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    7059 (THBS3)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    7059 (THBS3)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Phagocytosis
   Opsonins
    7059 (THBS3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   7059 (THBS3)
  Exosomal proteins of colorectal cancer cells
   7059 (THBS3)
  Exosomal proteins of bladder cancer cells
   7059 (THBS3)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   7059 (THBS3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: TSP_C TSP_3 COMP EGF_CA cEGF EGF_3 EGF Laminin_G_2
Motif
Other DBs
NCBI-GeneID: 7059
NCBI-ProteinID: NP_009043
OMIM: 188062
HGNC: 11787
Ensembl: ENSG00000169231
Vega: OTTHUMG00000035710
Pharos: P49746(Tbio)
UniProt: P49746
LinkDB All DBs
Position
1q22
AA seq 956 aa AA seqDB search
METQELRGALALLLLCFFTSASQDLQVIDLLTVGESRQMVAVAEKIRTALLTAGDIYLLS
TFRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADG
RTHTVLLRLRGPSRPSPALHLYVDCKLGDQHAGLPALAPIPPAEVDGLEIRTGQKAYLRM
QGFVESMKIILGGSMARVGALSECPFQGDESIHSAVTNALHSILGEQTKALVTQLTLFNQ
ILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRC
GPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDY
ARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHS
PAHSPCHIHAHCLFERNGAVSCQCNVGWAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQ
DNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACD
NCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDS
CPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECD
GDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAE
VTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGT
FHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSG
PGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQL
VADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVPEDFEPFRRQLLQGRV
NT seq 2871 nt NT seq  +upstreamnt  +downstreamnt
atggagacgcaggaacttcggggggccctggctcttctcctcctttgctttttcacatct
gccagtcaggatctgcaggtaattgacctgctgactgtgggcgagtctcggcagatggta
gctgtggcagagaagatccggacagccttgctcactgctggggacatctacctcttatcc
accttccgcctgccccccaagcagggtggtgtcctctttggcctctattctcgccaagac
aacactcgatggctggaggcctctgttgtaggcaagatcaacaaagtactggtgcgatac
cagcgggaggatggcaaagtccacgccgtgaacctacagcaagcgggcctggctgatggg
cgcacacacacagttctcctgcgactccgaggtccctccagacccagccctgccctacat
ctctacgtggactgcaaactgggtgaccaacatgcaggccttccagcactggcccccatt
cctccagcggaggtcgatgggctggagattaggactggacagaaggcgtatttgaggatg
cagggctttgtggaatctatgaaaattattctgggtgggtccatggcccgggtaggagcc
ctgagtgagtgtccattccaaggggacgagtccatccacagtgcagtgaccaatgcactg
cactccattctaggggagcagaccaaggcgctggtcacccaactcaccctcttcaaccag
atcctggtggagctgcgggatgatatacgagaccaggtgaaggaaatgtccctgatccga
aacaccattatggagtgtcaggtgtgcggcttccatgagcagcgttcccactgcagcccc
aatccctgcttccgaggtgtggactgcatggaagtgtacgagtacccaggctaccgctgt
gggccctgcccccctggcctgcagggcaacggcacccactgcagtgacatcaatgagtgt
gctcacgctgacccctgtttcccgggctccagctgcatcaacaccatgcccggcttccac
tgtgaggcctgtcctcgagggtacaagggcacacaggtgtctggtgtgggcattgactat
gcccgggccagcaaacaggtctgcaatgacatcgatgaatgcaacgatggcaacaatggt
ggctgtgacccaaactccatctgcaccaacactgtgggctctttcaagtgtggtccctgc
cgcctgggtttcctgggcaaccagagccagggctgcctcccagcccggacctgccacagc
ccagcccacagcccctgccacatccatgctcactgtctctttgaacgcaatggtgcagtg
tcctgccagtgtaacgtgggctgggctgggaatgggaacgtgtgtgggactgacacagac
atcgatggctacccagaccaagcactgccctgcatggacaacaacaaacactgcaaacag
gacaactgccttttgacacccaactctgggcaggaagatgctgataatgatggtgtgggg
gaccagtgtgatgatgatgctgatggggatgggatcaagaatgttgaggacaactgccgg
ctgttccccaacaaagaccagcagaactcagatacagattcatttggtgatgcctgtgac
aattgccccaacgttcccaacaatgaccagaaggacacagatggcaatggggaaggagat
gcctgtgacaacgacgtggatggggatggcatccccaatggattggacaattgccctaaa
gtccccaacccactacagacagacagggatgaggacggggtgggagatgcttgcgacagc
tgccctgaaatgagcaatcctacccagacagatgcagacagcgacctggtgggggatgtc
tgtgatactaatgaagacagcgatggggatgggcatcaggacaccaaggacaactgccca
cagctgccaaatagctcccagctggactctgataacgatggacttggagatgagtgtgat
ggggatgatgacaatgatggcatcccagattatgtgcctcctggtcccgataactgccgc
ctggtacccaatcccaatcagaaggactcagatggcaatggcgttggtgatgtgtgtgag
gatgactttgacaatgatgctgtggtcgaccccctggatgtgtgtcctgaaagtgcagag
gtaacgcttacggattttcgggcctatcagaccgtcgtcctggatcctgagggtgatgct
cagattgacccaaactgggttgtgctcaaccagggcatggaaatcgttcagaccatgaac
agtgaccctggcttggcagttggatacacggccttcaatggtgtggactttgaaggcacc
ttccatgtgaacacagtgactgatgatgactacgcaggctttctcttcagttatcaagac
agtggccgcttctacgtagtcatgtggaagcagaccgagcagacctactggcaggctaca
cccttccgggcggttgcccagcccgggctgcagctcaaggcagtgacatcagtgtctggc
ccaggtgagcacctccgaaatgccctgtggcatactggccacacccctgatcaggtacga
ctgctgtggacagacccacgaaatgtgggctggcgggacaagacctcctatcgctggcag
cttctgcaccggcctcaagttggctacattcgggtgaagctctatgagggaccccagctt
gtggcggattctggggtgatcattgacacatccatgcgaggggggcgtcttggtgtattc
tgcttctcccaagaaaacataatttggtccaatctccagtatcgatgcaatgacacagtg
cctgaggactttgagccattccggaggcagctgctccagggaagggtgtga

KEGG   Homo sapiens (human): 7060Help
Entry
7060              CDS       T01001                                 

Gene name
THBS4, TSP-4, TSP4
Definition
(RefSeq) thrombospondin 4
  KO
K04659  thrombospondin 2/3/4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05144  Malaria
hsa05165  Human papillomavirus infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    7060 (THBS4)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    7060 (THBS4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    7060 (THBS4)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    7060 (THBS4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    7060 (THBS4)
  09174 Infectious disease: parasitic
   05144 Malaria
    7060 (THBS4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    7060 (THBS4)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    7060 (THBS4)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    7060 (THBS4)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Phagocytosis
   Opsonins
    7060 (THBS4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   7060 (THBS4)
  Exosomal proteins of colorectal cancer cells
   7060 (THBS4)
  Exosomal proteins of bladder cancer cells
   7060 (THBS4)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   7060 (THBS4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: TSP_C TSP_3 COMP EGF_CA cEGF EGF_3 EGF
Motif
Other DBs
NCBI-GeneID: 7060
NCBI-ProteinID: NP_003239
OMIM: 600715
HGNC: 11788
Ensembl: ENSG00000113296
Vega: OTTHUMG00000108173
Pharos: P35443(Tbio)
UniProt: P35443
LinkDB All DBs
Position
5q14.1
AA seq 961 aa AA seqDB search
MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYV
ISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLA
DGRRHRILLRLSNLQRGAGSLELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQ
DFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDL
LRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQ
CTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGP
MVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA
ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSAR
NCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFG
DACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGD
ACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIG
DECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCP
ENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVD
FEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK
SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYE
GSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFD
N
NT seq 2886 nt NT seq  +upstreamnt  +downstreamnt
atgctggccccgcgcggagccgccgtcctcctgctgcacctggtcctgcagcggtggcta
gcggcaggcgcccaggccaccccccaggtctttgaccttctcccatcttccagtcagagg
ctaaacccaggcgctctgctgccagtcctgacagaccccgccctgaatgatctctatgtg
atttccaccttcaagctgcagactaaaagttcagccaccatcttcggtctttactcttca
actgacaacagtaaatattttgaatttactgtgatgggacgcttaaacaaagccatcctc
cgttacctgaagaacgatgggaaggtgcatttggtggttttcaacaacctgcagctggca
gacggaaggcggcacaggatcctcctgaggctgagcaatttgcagcgaggggccggctcc
ctagagctctacctggactgcatccaggtggattccgttcacaatctccccagggccttt
gctggcccctcccagaaacctgagaccattgaattgaggactttccagaggaagccacag
gacttcttggaagagctgaagctggtggtgagaggctcactgttccaggtggccagcctg
caagactgcttcctgcagcagagtgagccactggctgccacaggcacaggggactttaac
cggcagttcttgggtcaaatgacacaattaaaccaactcctgggagaggtgaaggacctt
ctgagacagcaggttaaggaaacatcatttttgcgaaacaccatagctgaatgccaggct
tgcggtcctctcaagtttcagtctccgaccccaagcacggtggtgcccccggctccccct
gcaccgccaacacgcccacctcgtcggtgtgactccaacccatgtttccgaggtgtccaa
tgtaccgacagtagagatggcttccagtgtgggccctgccccgagggctacacaggaaac
gggatcacctgtattgatgttgatgagtgcaaataccatccctgctacccgggcgtgcac
tgcataaatttgtctcctggcttcagatgtgacgcctgcccagtgggcttcacagggccc
atggtgcagggtgttgggatcagttttgccaagtcaaacaagcaggtctgcactgacatt
gatgagtgtcgaaatggagcgtgcgttcccaactcgatctgcgttaatactttgggatct
taccgctgtgggccttgtaagccggggtatactggtgatcagataaggggatgcaaagcg
gaaagaaactgcagaaacccagagctgaacccttgcagtgtgaatgcccagtgcattgaa
gagaggcagggggatgtgacatgtgtgtgtggagtcggttgggctggagatggctatatc
tgtggaaaggatgtggacatcgacagttaccccgacgaagaactgccatgctctgccagg
aactgtaaaaaggacaactgcaaatatgtgccaaattctggccaagaagatgcagacaga
gatggcattggcgacgcttgtgacgaggatgctgacggagatgggatcctgaatgagcag
gataactgtgtcctgattcataatgtggaccaaaggaacagcgataaagatatctttggg
gatgcctgtgataactgcctgagtgtcttaaataacgaccagaaagacaccgatggggat
ggaagaggagatgcctgtgatgatgacatggatggagatggaataaaaaacattctggac
aactgcccaaaatttcccaatcgtgaccaacgggacaaggatggtgatggtgtgggggat
gcctgtgacagttgtcctgatgtcagcaaccctaaccagtctgatgtggataatgatctg
gttggggactcctgtgacaccaatcaggacagtgatggagatgggcaccaggacagcaca
gacaactgccccaccgtcattaacagtgcccagctggacaccgataaggatggaattggt
gacgagtgtgatgatgatgatgacaatgatggtatcccagacctggtgccccctggacca
gacaactgccggctggtccccaacccagcccaggaggatagcaacagcgacggagtggga
gacatctgtgagtctgactttgaccaggaccaggtcatcgatcggatcgacgtctgccca
gagaacgcagaggtcaccctgaccgacttcagggcttaccagaccgtggtcctggatcct
gaaggggatgcccagatcgatcccaactgggtggtcctgaaccagggcatggagattgta
cagaccatgaacagtgatcctggcctggcagtggggtacacagcttttaatggagttgac
ttcgaagggaccttccatgtgaatacccagacagatgatgactatgcaggctttatcttt
ggctaccaagatagctccagcttctacgtggtcatgtggaagcagacggagcagacatat
tggcaagccaccccattccgagcagttgcagaacctggcattcagctcaaggctgtgaag
tctaagacaggtccaggggagcatctccggaactccctgtggcacacgggggacaccagt
gaccaggtcaggctgctgtggaaggactccaggaatgtgggctggaaggacaaggtgtcc
taccgctggttcctacagcacaggccccaggtgggctacatcagggtacgattttatgaa
ggctctgagttggtggctgactctggcgtcaccatagacaccacaatgcgtggaggccga
cttggcgttttctgcttctctcaagaaaacatcatctggtccaacctcaagtatcgctgc
aatgacaccatccctgaggacttccaagagtttcaaacccagaatttcgaccgcttcgat
aattaa

KEGG   Homo sapiens (human): 7143Help
Entry
7143              CDS       T01001                                 

Gene name
TNR, TN-R
Definition
(RefSeq) tenascin R
  KO
K06252  tenascin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05165  Human papillomavirus infection
hsa05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    7143 (TNR)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    7143 (TNR)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    7143 (TNR)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    7143 (TNR)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    7143 (TNR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    7143 (TNR)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   7143 (TNR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: fn3 Fibrinogen_C EGF_Tenascin EGF_2 Pur_ac_phosph_N Uroplakin_II EGF
Motif
Other DBs
NCBI-GeneID: 7143
NCBI-ProteinID: NP_003276
OMIM: 601995
HGNC: 11953
Ensembl: ENSG00000116147
Vega: OTTHUMG00000034876
Pharos: Q92752(Tbio)
UniProt: Q92752 A1L306
LinkDB All DBs
Position
1q25.1
AA seq 1358 aa AA seqDB search
MGADGETVVLKNMLIGINLILLGSMIKPSECQLEVTTERVQRQSVEEEGGIANYNTSSKE
QPVVFNHVYNINVPLDNLCSSGLEASAEQEVSAEDETLAEYMGQTSDHESQVTFTHRINF
PKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNANCCQESAATGQLDYIPHCSGHGN
FSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCS
SRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNA
CSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQ
PTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQG
LQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEY
IVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGL
VGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNL
RVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGT
EYGVGISAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF
TPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL
HFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEY
IVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRP
TQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLI
ATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTAT
MYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDG
SRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFPHPQDCAQ
HLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVG
FGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQEAAFASYDRFSVEDSRNLYKLRIGSY
NGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQG
INWYHWKGHEFSIPFVEMKMRPYNHRLMAGRKRQSLQF
NT seq 4077 nt NT seq  +upstreamnt  +downstreamnt
atgggggcagatggggaaacagtggttctgaagaacatgctcattggcatcaacctgatc
cttctgggctccatgatcaagccttcagagtgtcagctggaggtcaccacagaaagggtc
cagagacagtcagtggaggaggagggaggcattgccaactacaacacatccagcaaagag
cagcctgtggtcttcaaccacgtgtacaacattaacgtgcccttggacaacctctgctcc
tcagggctagaggcctctgctgagcaggaggtgagtgcagaagacgagactctggcagag
tacatgggccagacctcagaccacgagagccaggtcacctttacacacaggatcaacttc
cccaaaaaggcctgtccatgtgccagttcagcccaggtgctgcaggagctgctgagccgg
atcgagatgctggagagggaggtgtcggtgctgcgagaccagtgcaacgccaactgctgc
caagaaagtgctgccacaggacaactggactatatccctcactgcagtggccacggcaac
tttagctttgagtcctgtggctgcatctgcaacgaaggctggtttggcaagaattgctcg
gagccctactgcccgctgggttgctccagccggggggtgtgtgtggatggccagtgcatc
tgtgacagcgagtacagcggggatgactgttccgaactccggtgcccaacagactgcagc
tcccgggggctctgcgtggacggggagtgtgtctgtgaagagccctacactggcgaggac
tgcagggaactgaggtgccctggggactgttcggggaaggggagatgtgccaacggtacc
tgtttatgcgaggagggctacgttggtgaggactgcggccagcggcagtgtctgaatgcc
tgcagtgggcgaggacaatgtgaggaggggctctgcgtctgtgaagagggctaccagggc
cctgactgctcagcagttgcccctccagaggacttgcgagtggctggtatcagcgacagg
tccattgagctggaatgggacgggccgatggcagtgacggaatatgtgatctcttaccag
ccgacggccctggggggcctccagctccagcagcgggtgcctggagattggagtggtgtc
accatcacggagctggagccaggtctcacctacaacatcagcgtctacgctgtcattagc
aacatcctcagccttcccatcactgccaaggtggccacccatctctccactcctcaaggg
ctacaatttaagacgatcacagagaccaccgtggaggtgcagtgggagcccttctcattt
tccttcgatgggtgggaaatcagcttcattccaaagaacaatgaagggggagtgattgct
caggtccccagcgatgttacgtcctttaaccagacaggactaaagcctggggaggaatac
attgtcaatgtggtggctctgaaagaacaggcccgcagcccccctacctcggccagcgtc
tccacagtcattgacggccccacgcagatcctggttcgcgatgtctcggacactgtggct
tttgtggagtggattccccctcgagccaaagtcgatttcattcttttgaaatatggcctg
gtgggcggggaaggtgggaggaccaccttccggctgcagcctcccctgagccaatactca
gtgcaggccctgcggcctggctcccgatacgaggtgtcagtcagtgccgtccgagggacc
aacgagagcgattctgccaccactcagttcacaacagagatcgatgcccccaagaacttg
cgagttggttctcgcacagcaaccagccttgacctcgagtgggataacagtgaagccgaa
gttcaggagtacaaggttgtgtacagcaccctggcgggtgagcaatatcatgaggtactg
gtccccaggggcattggtccaaccaccagggccaccctgacagatctggtacctggcact
gagtatggagttggaatatctgccgtcatgaactcacagcaaagcgtgccagccaccatg
aatgccaggactgaacttgacagtccccgagacctcatggtgacagcctcctcggagacc
tccatctccctcatctggaccaaggccagtggccccattgaccactaccgaattaccttt
accccatcctctgggattgcctcagaagtcaccgtacccaaggacaggacctcatacaca
ctaacagatctagagcctggggcagagtacatcatttccgtcactgctgagaggggtcgg
cagcagagcttggagtccactgtggatgctttcacaggcttccgtcccatctctcatctg
cacttttctcatgtgacctcctccagtgtgaacatcacttggagtgatccatctccccca
gcagacagactcattcttaactacagccccagggatgaggaggaagagatgatggaggtc
tccctggatgccaccaagaggcatgctgtcctgatgggcctgcaaccagccacagagtat
attgtgaaccttgtggctgtccatggcacagtgacctctgagcccattgtgggctccatc
accacaggaattgatcccccaaaagacatcacaattagcaatgtgaccaaggactcagtg
atggtctcctggagccctcctgttgcatctttcgattactaccgagtatcatatcgaccc
acccaagtgggacgactagacagctcagtggtgcccaacactgtgacagaattcaccatc
accagactgaacccagctaccgaatacgaaatcagcctcaacagcgtgcggggcagggag
gaaagcgagcgcatctgtactcttgtgcacacagccatggacaaccctgtggatctgatt
gctaccaatatcactccaacagaagccctgctgcagtggaaggcaccagtgggtgaggtg
gagaactacgtcattgttcttacacactttgcagtcgctggagagaccatccttgttgac
ggagtcagtgaggaatttcggcttgttgacctgcttcctagcacccactatactgccacc
atgtatgccaccaatggacctctcaccagtggcaccatcagcaccaacttttctactctc
ctggaccctccggcaaacctgacagccagtgaagtcaccagacaaagtgccctgatctcc
tggcagcctcccagggcagagattgaaaattatgtcttgacctacaaatccaccgatgga
agccgcaaggagctgattgtggatgcagaagacacctggattcgactggagggcctgttg
gagaacacagactacacggtgctcctgcaggcagcacaggacaccacgtggagcagcatc
acctccaccgctttcaccacaggaggccgggtgttccctcatccccaagactgtgcccag
catttgatgaatggagacactttgagtggggtttaccccatcttcctcaatggggagctg
agccagaaattacaagtgtactgtgatatgaccaccgacgggggcggctggattgtattc
cagaggcggcagaatggccaaactgattttttccggaaatgggctgattaccgtgttggc
ttcgggaacgtggaggatgagttctggctggggctggacaatatacacaggatcacatcc
cagggccgctatgagctgcgcgtggacatgcgggatggccaagaggccgccttcgcctcc
tacgacaggttctctgtcgaggacagcagaaacctgtacaaactccgcataggaagctac
aacggcactgcgggggactccctcagctatcatcaaggacgccctttctccacagaggat
agagacaatgatgttgcagtgactaactgtgccatgtcgtacaagggagcatggtggtat
aagaactgccaccggaccaacctcaatgggaagtacggggagtccaggcacagtcagggc
atcaactggtaccattggaaaggccatgagttctccatcccctttgtggaaatgaagatg
cgcccctacaaccaccgtctcatggcagggagaaaacggcagtccttacagttctga

KEGG   Homo sapiens (human): 7148Help
Entry
7148              CDS       T01001                                 

Gene name
TNXB, EDS3, EDSCLL, EDSCLL1, HXBL, TENX, TN-X, TNX, TNXB1, TNXB2, TNXBS, VUR8, XB, XBS
Definition
(RefSeq) tenascin XB
  KO
K06252  tenascin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05165  Human papillomavirus infection
hsa05206  MicroRNAs in cancer
Disease
H00802  Ehlers-Danlos syndrome
H01037  Vesicoureteral reflux
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    7148 (TNXB)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    7148 (TNXB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    7148 (TNXB)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    7148 (TNXB)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    7148 (TNXB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    7148 (TNXB)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   7148 (TNXB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: fn3 Fibrinogen_C EGF_2 EGF_Tenascin DUF2369 hEGF
Motif
Other DBs
NCBI-GeneID: 7148
NCBI-ProteinID: NP_061978
OMIM: 600985
HGNC: 11976
Ensembl: ENSG00000168477
Vega: OTTHUMG00000031088
Pharos: P22105(Tbio)
UniProt: P22105 Q9Y464 O95680 O95681
LinkDB All DBs
Structure
PDB: 

Position
6p21.33-p21.32
AA seq 4242 aa AA seqDB search
MMPAQYALTSSLVLLVLLSTARAGPFSSRSNVTLPAPRPPPQPGGHTVGAGVGSPSSQLY
EHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQ
CTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSP
PSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFS
GPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPG
YTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCW
PGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCV
CWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGR
CMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCED
GVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVC
QDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRG
RCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCP
GDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYE
IQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMI
DGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMP
GVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRP
QELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPP
PPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLL
RWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHG
PLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRP
QVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLE
QPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLD
PDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTV
TGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHL
YGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQ
FDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVT
APLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQV
VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGEL
WVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFL
LYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPE
GQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVA
ITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDG
QLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTA
TPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGV
TISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGE
LTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYK
MHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQ
FDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLT
APGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNG
DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTE
PSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGE
ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP
EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGL
EPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDAT
PDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFH
GGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQ
GHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVG
VTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGD
GQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEP
STEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEE
SEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPR
LGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDH
KYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSL
SLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQR
VGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQ
PQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELT
VTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFL
LYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQ
YRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTP
APELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLV
DGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLS
VTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRD
LRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSR
ADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLT
TVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHD
LVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAG
YLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGL
RIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDF
WRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAA
EYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNG
LYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG
NT seq 12729 nt NT seq  +upstreamnt  +downstreamnt
atgatgccagcccagtatgctctaacctccagcctggttctcctggtgctgctgagcaca
gccagagcaggccccttctcttcacggtccaatgtgacactgccagccccccggccccct
ccccagccagggggccacacagtgggggctggagtgggaagcccctcttctcagctttac
gagcacacagtggaaggaggggagaagcaggtggtattcacccaccgcattaacctgccc
ccttccactggctgtggctgtcccccaggcaccgagcccccagtccttgcttcagaggta
caggccctgagggtccgtctagagatcctggaggagttggtgaaggggctcaaggaacag
tgcactgggggatgttgtcctgcctctgcccaagctggcacaggtcagacagatgtgcgg
accctctgcagtctccatggtgtgtttgatctgagccgctgcacctgttcctgtgagcca
ggctggggtgggcccacctgctcagaccccacagatgctgagatccctccctcttcccca
ccctcagcctcggggtcctgcccagatgactgcaatgatcagggtcgctgtgtccgtggt
cgttgcgtgtgctttcccggctacactggccccagctgtggctggccatcctgtcccggg
gactgccaaggccgtgggcgctgcgtgcagggcgtgtgtgtgtgccgggcaggcttctca
ggccccgactgcagccagcgctcctgccctcgaggttgcagccagaggggacgctgtgag
ggtgggcgctgcgtgtgtgacccaggctacactggtgacgactgtggcatgaggagctgc
cctcgcggttgcagtcagagggggcgctgtgagaatgggcgctgcgtgtgtaaccccggc
tacactggcgaggactgtggggtgaggagctgccctcggggctgcagccagcggggacgc
tgcaaggacgggcgctgcgtgtgtgaccccggctacactggcgaggactgtggtacgcgg
agctgcccctgggactgtggcgagggcgggcgctgcgtggacggccgctgcgtgtgctgg
cccgggtacacaggcgaggactgcagcacgcggacatgtccgagggactgccggggccgc
gggcgctgcgaggacggcgaatgcatttgcgacacgggctacagcggggacgactgcggc
gtgcgcagctgccctggcgactgcaaccaaaggggccgctgcgaggacggccgctgcgtg
tgctggccggggtacactggaaccgattgcggctcgcgcgcctgcccacgcgactgtaga
ggtcgcgggcgctgcgagaacggcgtgtgtgtttgcaatgcgggctacagcggcgaggac
tgcggtgtgcgcagctgtcctggggactgtcgtggccggggccgctgtgagagtggccgc
tgcatgtgttggccggggtacacaggccgggactgcggcacgcgcgcctgtcctggcgac
tgtcgcgggcgcgggcgctgcgtggatggccgctgcgtgtgcaacccgggcttcaccggt
gaggactgtgggagccgtcgctgtcccggggactgccgtgggcacggcctttgcgaggat
ggcgtgtgcgtgtgtgacgcaggctactcaggggaagactgcagcacgcgcagctgcccc
gggggctgccgaggccgcggccagtgcctagatgggcggtgtgtgtgcgaggacggctac
tctggcgaggattgcggtgtgaggcagtgcccgaatgactgcagccagcacggcgtgtgc
caggacggtgtgtgcatctgttgggaaggctacgtgagtgaggactgcagcatccgcacc
tgcccctccaactgccacgggaggggccgctgtgaggaagggcgctgcctgtgcgaccca
ggctacaccggccctacctgtgccacccgcatgtgcccggctgactgccggggacgtggg
cggtgtgtgcaaggagtgtgcctgtgccacgtgggctatggcggtgaggactgcgggcag
gaagagcctccagccagcgcctgccctggaggctgcgggccccgggaactgtgccgggca
ggccagtgtgtgtgtgtagagggcttccgaggccctgactgtgccatccagacatgccca
ggggactgccgtggccgaggagagtgtcacgatggcagctgtgtctgcaaagatgggtat
gctggcgaagactgcggagaagaggtgccaaccattgagggcatgaggatgcatctcttg
gaggagacaacagttcggacagagtggaccccggctcctggccccgtggatgcctatgaa
attcagttcatccccacgacagagggggcgagccccccattcacagcacgggttccaagc
tctgcctcagcctatgaccagagaggactggcccctggacaggagtaccaggtcactgtc
cgagcccttcgagggaccagctggggccttcctgcctccaagaccatcaccaccatgatc
gatgggccccaggacctccgagtggtggctgtgacaccgacaacactggagcttggctgg
ctgcgtccccaggctgaggtggaccgatttgtggtgtcctacgtcagtgccggcaaccag
agggtgaggctggaagtgccccctgaagcagacgggacgctgctgactgacctgatgcca
ggcgtagaatatgtggtgactgtcacagcggagcggggccgggcagtcagctacccagct
tctgtcagggccaacacagggtcctcacccttgggcctcttggggactaccgatgagcct
cctccctcaggcccctcgacgacgcaaggggcccaggctcctctcctgcagcagcgcccc
caggagctgggagagttgagggtgctgggcagagatgagacagggcgcctccgtgtggtc
tggaccgcccagcctgacacctttgcctacttccaactgcgcatgcgggtgcccgagggg
ccgggggcacatgaggaagtgctgccaggggacgtccgccaggctctggtgcctccaccc
cctcctggaaccccgtatgagctgtcacttcatggggtccctcctgggggcaagccctct
gaccccatcatctaccaaggcattatggacaaggatgaggagaagcctgggaagtcctca
ggcccaccacgcctgggtgagctgacggtgacagacaggacctccgactccttgctcctg
cgctggacggtccccgagggcgagtttgactccttcgtgatccagtacaaagacagggac
gggcagccccaggtggtgcccgtggaaggaccccagcgctcggccgtcatcacctccctg
gatcctggccgcaagtacaaatttgtcctgtatgggtttgttggcaagaagaggcatggt
ccgctggtggctgaagccaagatcttgcctcagagtgacccaagtccagggactccaccc
cacctgggaaacctgtgggtgacagaccctaccccagattcactgcacctctcctggact
gtccctgagggccagtttgacaccttcatggtccagtacagggacagggatggacggccc
caggtggtacctgtggaagggcccgagcgttcatttgttgtctcctcactggaccctgac
cacaagtacagattcactctgtttggaattgcgaacaagaagcggtatggccccctcacg
gccgatggcaccactgctccagagaggaaagaggagcccccccgccctgagttcctggag
cagcccctcctgggggaactgacagtgaccggcgtgaccccagactccttgcgtctctca
tggacagtggcccagggccccttcgactcattcatggtccagtacaaggatgcacagggg
cagccccaggcagtgcctgttgcgggggatgagaatgaggttactgtccccggcctggat
cccgaccggaagtataagatgaacctctacgggcttcgtggcaggcagcgtgtggggccc
gagtctgtggtggccaagactgctcctcaggaggatgtggacgagacccccagccccaca
gaactgggcacggaggccccggagtcccccgaggagccgctcctgggggagctgacagtg
acaggatcctcccctgattcgctgagcctcttctggaccgtcccccagggcagcttcgac
tctttcaccgtgcagtacaaggacagggatgggcggccccgggcggtgcgtgttgggggc
aaggagagtgaggtcaccgtgggaggcctagagcccgggcacaagtacaagatgcacctg
tacggcctccacgaggggcagcgcgtgggcccggtgtccgccgtgggcgtgacagcccca
caacaagaagagacccctccagccactgagtccccgctggagccacgcctaggagagctg
acagtgacagatgtgacccccaactctgtgggcctctcctggacagtccccgagggccag
tttgactccttcatagtccagtacaaggacaaggacgggcagccccaggtggtgccggtg
gcggcagaccagcgagaggtcacagtctacaacctggagcctgagagaaaatataagatg
aacatgtatggactacatgatgggcaacgcatgggccccctgtctgtggtcatcgtgacg
gctcccctcccaccagccccagccacagaggcctccaagcctcccctggagccacgccta
ggggagctgacagtgacggatataacccctgactctgtgggcctctcatggacagtccct
gagggtgaattcgactcctttgtggttcagtacaaggacagggacgggcagccccaggtg
gtgcccgtggctgcagatcagcgggaggtcactatccctgacctggaaccctcccgcaag
tacaagttcctgctctttgggatccaggatgggaaacgacgcagcccagtctctgtggag
gcaaagacggttgcccgaggtgacgccagcccaggggccccaccccgccttggggagctg
tgggtgacagaccccaccccagactcactgcgcctctcctggacggttcctgagggccag
ttcgactcttttgtggtccagttcaaggacaaagacgggccccaggtggtgcccgtggag
ggccatgagcgctctgtcactgtcacccctctggatgccggccgcaagtacagattcctc
ctctatggcctcctgggcaagaagcgccatggccctctcactgccgacggcaccacggaa
gcccggagtgctatggatgatactggaacaaagcgtcccccaaaaccccgtctgggggag
gagctgcaggtgaccaccgtgacccagaactccgtgggcctctcctggacagtccctgag
ggccagtttgactcctttgtggtccagtacaaagacagggacgggcagccccaggtggtg
cccgtggagggcagcctcagggaggtcagcgtgccgggcctggaccctgcccacaggtac
aagctgctgctctacgggctgcaccacggcaagcgtgtgggccccatctcggccgtcgcc
attactgccggcagggaagaaacggaaactgagaccacggccccgacccctccagcgcct
gagccccacctcggggagttgacagtggaggaggccacgtcacacaccctgcatctctcc
tggatggtgactgagggagaatttgactccttcgaaatccagtacacagatagagacggg
caactccaaatggtccgcataggaggtgaccggaatgacatcaccctctctggcctggaa
tccgaccacagatacctggtgaccctgtatggtttcagtgatgggaagcatgtaggtcct
gtccatgtcgaggccctgacagtcccggaggaggagaagccttcagaacctcccaccgca
acccccgagccccccatcaagcctcgcctgggggagctgaccgtgacagatgccacccct
gactccctcagcctgtcctggacagttcccgagggacagtttgaccacttcctggtccag
tacaggaatggagatgggcagcccaaggcagtgagggtgccagggcacgaggaaggggtc
accatctcgggcctggagccagaccataaatacaagatgaacctgtacggcttccacggt
ggccagcgcatgggccctgtgtctgtcgtcggggtgacagctgcagaggaagagaccccc
agccccacagaacccagcatggaggccccggagcccgctgaggagccgctcctgggggag
ctaacagtgacaggatcctcccctgactcgctgagcctctcctggaccgtcccccagggc
cgcttcgactccttcaccgtgcagtacaaggacagggacgggcggccccaggtggtgcgt
gttgggggcgaggagagtgaagtcaccgtggggggcctggagcctgggcgcaagtacaag
atgcacctgtacggcctccacgaggggcggcgcgtgggcccagtgtctgctgtgggcgtc
acggcccccgaagaggagtcccctgatgctcctcttgcaaagctgcgcctagggcagatg
acagtgagagacatcacctccgactccctcagcctctcctggacagtccccgagggccag
tttgaccatttcttggtccagtttaagaatggggacgggcagcccaaggcggtgcgggtg
ccgggacacgaggatggggtcaccatctcgggcctggagccagaccacaagtacaagatg
aacctgtacggcttccacggtggccagcgcgtgggccccgtgtctgctgttggtttaact
gccccaggaaaggatgaagaaatggccccagcctcgacagaacctcccacccctgaaccc
cccatcaagcctcgcctggaggagctgaccgtgacagatgcgacccctgactccctcagc
ctgtcctggacggttcccgagggacagtttgaccacttcctggtccagtacaagaatggg
gatgggcagcccaaggcaacacgggtgccaggacatgaggacagggtcaccatctccggc
ctggagccagacaacaagtacaagatgaacctgtacggcttccacggtggccagcgtgtg
ggccccgtgtctgccatcggggtgacagctgcagaggaagagacccccagccccacagaa
cccagcatggaggccccggagccccctgaggagccgctcctgggggagctaacagtgaca
ggatcctcccctgactcgctgagcctctcctggaccgtcccccagggccgcttcgactcc
ttcaccgtgcagtacaaggacagggacgggcggccccaggtggtgcgtgttgggggcgag
gagagcgaggtcaccgtggggggcctggagcctgggcgcaaatacaagatgcacctgtat
ggcctccacgaggggcggcgcgtgggcccggtgtccaccgtgggcgtgactgccccacaa
gaggatgtggacgagacccccagccctacagaaccaggcacagaggccccagggcccccc
gaggagcctctcctgggggagctgacagtgacaggatcctcccctgactcgctgagcctt
tcctggaccgtcccccagggccgctttgactccttcaccgtgcagtacaaggacagggac
gggcggccccaggcggtgcgtgttgggggccaggagagcaaggtcactgtgaggggcctg
gagcctgggcgcaagtacaagatgcacctgtacggcctccacgaggggcggcgcctgggc
ccggtgtctgccgtgggcgtcacagaggatgaagccgagaccacccaagcagtgcctacc
atgacccctgagccccccatcaagcctcgcctgggggagctgaccatgacagatgccacc
cctgactccctcagcctgtcctggacggttcccgagggccagtttgaccacttcctggtc
cagtacaggaatggggatgggcagcccaaggcggtgcgggtgccggggcacgaggacggg
gtcaccatctcaggcctggagccagaccataaatacaagatgaacctgtacggcttccac
ggtggccagcgcgtgggccccatctctgtcattggggtgacggctgcagaggaagagacc
cccagccccacggaactcagcactgaggccccggagccccctgaggagccgctcctgggg
gagctgacagtgacaggatcctcccctgactcgctgagcctctcctggaccatcccccag
ggccacttcgactccttcaccgtgcagtacaaggacagggacgggcggccccaggtgatg
cgtgtcaggggcgaggagagcgaggtcaccgtggggggcctggagcccgggcgcaaatac
aagatgcacctgtacggcctccacgaggggcggcgtgtgggcccggtgtccaccgtgggt
gtgacagaggatgaagcagagaccacccaagcagtgcccaccacaacccctgagcccccc
aacaagcctcgcctcggggagctgaccgtgacagatgccacccctgactccctcagcctg
tcctggatggtccccgagggccagtttgaccacttcctggtccagtacaggaatggggat
gggcagcccaaggtggtgcgggtgccggggcacgaggacggggtcaccatctcaggcctg
gagccagaccacaagtacaagatgaacctgtacggcttccacggtggccagcgcgtgggc
cccatctctgtcattggggtgacagctgcagaggaagaaactcccgcccccacagaaccc
agcacggaggccccggagccccctgaggagccgctcctgggggagctgacagtgacagga
tcctcccctgactcgctgagcctctcctggaccatcccccagggccgcttcgactccttc
actgtgcagtacaaggacagggacgggcggccccaggtggtgcgtgtcaggggcgaggag
agcgaggtcaccgtggggggcctggagcccgggtgcaaatacaagatgcacctgtacggc
ctccacgaggggcagcgcgtgggcccagtgtccgctgtgggtgtgacagctccaaaggat
gaagccgagaccacccaagcagtgcctaccatgacccctgagccccccatcaagcctcgc
ctgggggagctgaccgtgacagatgccacccccgactccctcagcctgtcctggatggtt
cccgagggccagtttgaccacttcctggtccagtacaggaatggggatgggcagcccaag
gcggtgcgggtgccggggcacgaggacggggtcaccatctcaggcctggagccagaccat
aaatacaagatgaacctgtacggcttccacggtggccagcgcgtaggccctgtgtctgcc
attggggtgacggaggaagagacccccagccccacagaacccagcactgaggccccggag
gcccctgaggagccgctcctgggggagttgacagtgacaggatcctcccctgactcgctg
agcctctcctggaccgtcccccagggccgcttcgactccttcaccgtgcagtacaaggac
agggacgggcagccccaggtggtgcgtgtcaggggcgaggagagcgaggtcaccgtgggg
ggcctggagcccgggcgcaaatacaagatgcatctgtacggcctccacgaggggcagcgc
gtgggcccagtgtccaccgtgggcatcacggcgcccctgcccacaccactgccggtggag
ccccgcctgggggagctggcggtggcggccgtgacctcggactcagtgggcctctcatgg
acggtggcccagggcccctttgactccttcctggtacagtacagggacgcgcaggggcag
ccccaggcagtgcctgtgagcggagacctccgagcggtcgccgtctcggggctggacccg
gcccgcaagtacaagttcctgctctttggactccagaatgggaaacgccacggcccagtc
cctgtggaggccaggaccgccccagacaccaaaccgtctccccgcctgggggagctgact
gtgacagatgcgacccctgactccgtgggcctctcgtggacggtccctgagggcgaattc
gactccttcgtggtccagtacaaggataaggatggtcggctccaggtggtgccggtggca
gccaaccagcgggaggtcacagtccagggcctggagcccagtaggaaatacaggttcctg
ctctatggtctgtcaggcaggaaacgactgggccccatctctgctgacagcaccacagct
cccctggagaaggagctacctccccacctgggggaactgaccgtggctgaggagacctcc
agctctctgcgcctgtcctggacggtagcccagggcccctttgactccttcgtggtccag
tacagggacacggacgggcagcccagggcagtgcctgtggccgcagaccagcgcacagtc
accgtagaggacctggagcctggcaagaaatacaagtttctgctctacgggctccttggg
ggaaagcgcctgggcccggtctctgccctgggaatgacagccccagaagaggacacacca
gccccagagttagccccagaggcccctgagcctcctgaagagccccgcctaggagtgctg
accgtgaccgacacaaccccagactccatgcgcctctcgtggagcgtggcccagggcccc
tttgattccttcgtggtccagtatgaggacacgaacgggcagccccaggccttgctcgtg
gacggcgaccagagcaagatcctcatctcaggcctggagcccagcaccccctacaggttc
ctcctctatggcctccatgaagggaagcgcctggggcccctctcagctgagggcaccaca
gggctggctcctgctggtcagacctcagaggagtcaaggccccgcctgtcccagctgtct
gtgactgacgtgaccaccagttcactgaggctcaactgggaggccccaccgggggccttc
gactccttcctgctccgctttggggttccatcaccaagcactctggagccgcatccgcgt
ccactgctgcagcgcgagctgatggtgccggggacgcggcactcggccgtgctccgggac
ctgcgttccgggactctgtacagcctgacactgtatgggctgcgaggaccccacaaggcc
gacagcatccagggaaccgcccgcaccctcagcccagttctggagagcccccgtgacctc
caattcagtgaaatcagggagacctcagccaaggtcaactggatgcccccaccatcccgg
gcggacagcttcaaagtctcctaccagctggcggacggaggggagcctcagagtgtgcag
gtggatggccaggcccggacccagaaactccaggggctgatcccaggcgctcgctatgag
gtgaccgtggtctcggtccgaggctttgaggagagtgagcctctcacaggcttcctcacc
acggttcctgacggtcccacacagttgcgtgcactgaacttgaccgagggattcgccgtg
ctgcactggaagcccccccagaatcctgtggacacctatgacgtccaggtcacagcccct
ggggccccgcctctgcaggcggagaccccaggcagcgcggtggactaccccctgcatgac
cttgtcctccacaccaactacaccgccacagtgcgtggcctgcggggccccaacctcact
tccccagccagcatcaccttcaccacagggctagaggcccctcgggacttggaggccaag
gaagtgaccccccgcaccgccctgctcacttggactgagcccccagtccggcccgcaggc
tacctgctcagcttccacacccctggtggacagaaccaggagatcctgctcccaggaggg
atcacatctcaccagctccttggcctctttccctccacctcctacaatgcacggctccag
gccatgtggggccagagcctcctgccgcccgtgtccacctctttcaccacgggtgggctg
cggatccccttccccagggactgcggggaggagatgcagaacggagccggtgcctccagg
accagcaccatcttcctcaacggcaaccgcgagcggcccctgaacgtgttttgcgacatg
gagactgatgggggcggctggctggtgttccagcgccgcatggatggacagacagacttc
tggagggactgggaggactatgcccatggttttgggaacatctctggagagttctggctg
ggcaatgaggccctgcacagcctgacacaggcaggtgactactccatgcgcgtggacctg
cgggctggggacgaggctgtgttcgcccagtacgactccttccacgtagactcggctgcg
gagtactaccgcctccacttggagggctaccacggcaccgcaggggactccatgagctac
cacagcggcagtgtcttctctgcccgtgatcgggaccccaacagcttgctcatctcctgc
gctgtctcctaccgaggggcctggtggtacaggaactgccactacgccaacctcaacggg
ctctacgggagcacagtggaccatcagggagtgagctggtaccactggaagggcttcgag
ttctcggtgcccttcacggaaatgaagctgagaccaagaaactttcgctccccagcgggg
ggaggctga

KEGG   Homo sapiens (human): 7448Help
Entry
7448              CDS       T01001                                 

Gene name
VTN, V75, VN, VNT
Definition
(RefSeq) vitronectin
  KO
K06251  vitronectin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04610  Complement and coagulation cascades
hsa05165  Human papillomavirus infection
hsa05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    7448 (VTN)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    7448 (VTN)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    7448 (VTN)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    7448 (VTN)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    7448 (VTN)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    7448 (VTN)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    7448 (VTN)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    7448 (VTN)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   7448 (VTN)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   7448 (VTN)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hemopexin Somatomedin_B
Motif
Other DBs
NCBI-GeneID: 7448
NCBI-ProteinID: NP_000629
OMIM: 193190
HGNC: 12724
Ensembl: ENSG00000109072
Vega: OTTHUMG00000132500
Pharos: P04004(Tbio)
UniProt: P04004 D9ZGG2
LinkDB All DBs
Structure
PDB: 

Position
17q11.2
AA seq 478 aa AA seqDB search
MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKP
QVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEE
EAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYC
YELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYP
RNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSA
VFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMA
PRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY
RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL
NT seq 1437 nt NT seq  +upstreamnt  +downstreamnt
atggcacccctgagaccccttctcatactggccctgctggcatgggttgctctggctgac
caagagtcatgcaagggccgctgcactgagggcttcaacgtggacaagaagtgccagtgt
gacgagctctgctcttactaccagagctgctgcacagactatacggctgagtgcaagccc
caagtgactcgcggggatgtgttcactatgccggaggatgagtacacggtctatgacgat
ggcgaggagaaaaacaatgccactgtccatgaacaggtggggggcccctccctgacctct
gacctccaggcccagtccaaagggaatcctgagcagacacctgttctgaaacctgaggaa
gaggcccctgcgcctgaggtgggcgcctctaagcctgaggggatagactcaaggcctgag
acccttcatccagggagacctcagcccccagcagaggaggagctgtgcagtgggaagccc
ttcgacgccttcaccg