KEGG   Homo sapiens (human): 10554
Entry
10554             CDS       T01001                                 

Gene name
AGPAT1, 1-AGPAT1, G15, LPAAT-alpha, LPAATA
Definition
(RefSeq) 1-acylglycerol-3-phosphate O-acyltransferase 1
  KO
K13509  lysophosphatidate acyltransferase [EC:2.3.1.51]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00561  Glycerolipid metabolism
hsa00564  Glycerophospholipid metabolism
hsa01100  Metabolic pathways
hsa04072  Phospholipase D signaling pathway
hsa04975  Fat digestion and absorption
Module
hsa_M00089  Triacylglycerol biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    10554 (AGPAT1)
   00564 Glycerophospholipid metabolism
    10554 (AGPAT1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    10554 (AGPAT1)
 09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    10554 (AGPAT1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:hsa01004]
    10554 (AGPAT1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.51  1-acylglycerol-3-phosphate O-acyltransferase
     10554 (AGPAT1)
Lipid biosynthesis proteins [BR:hsa01004]
 Phospholipid acyltransferase
  LPAAT/LPLAT
   10554 (AGPAT1)
SSDB
Motif
Pfam: Acyltransferase DUF2706
Other DBs
NCBI-GeneID: 10554
NCBI-ProteinID: NP_006402
OMIM: 603099
HGNC: 324
Ensembl: ENSG00000204310
Vega: OTTHUMG00000031210
Pharos: Q99943(Tbio)
UniProt: Q99943 A0A024RCV5
LinkDB
Position
6p21.32
AA seq 283 aa
MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVRG
RNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLPGR
CVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGT
RNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVPTE
GLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGGG
NT seq 852 nt   +upstreamnt  +downstreamnt
atggatttgtggccaggggcatggatgctgctgctgctgctcttcctgctgctgctcttc
ctgctgcccaccctgtggttctgcagccccagtgccaagtacttcttcaagatggccttc
tacaatggctggatcctcttcctggctgtgctcgccatccctgtgtgtgccgtgcgagga
cgcaacgtcgagaacatgaagatcttgcgtctaatgctgctccacatcaaatacctgtac
gggatccgagtggaggtgcgaggggctcaccacttccctccctcgcagccctatgttgtt
gtctccaaccaccagagctctctcgatctgcttgggatgatggaggtactgccaggccgc
tgtgtgcccattgccaagcgcgagctactgtgggctggctctgccgggctggcctgctgg
ctggcaggagtcatcttcatcgaccggaagcgcacgggggatgccatcagtgtcatgtct
gaggtcgcccagaccctgctcacccaggacgtgagggtctgggtgtttcctgagggaacg
agaaaccacaatggctccatgctgcccttcaaacgtggcgccttccatcttgcagtgcag
gcccaggttcccattgtccccatagtcatgtcctcctaccaagacttctactgcaagaag
gagcgtcgcttcacctcgggacaatgtcaggtgcgggtgctgcccccagtgcccacggaa
gggctgacaccagatgacgtcccagctctggctgacagagtccggcactccatgctcact
gttttccgggaaatctccactgatggccggggtggtggtgactatctgaagaagcctggg
ggcggtgggtga

KEGG   Homo sapiens (human): 10555
Entry
10555             CDS       T01001                                 

Gene name
AGPAT2, 1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta
Definition
(RefSeq) 1-acylglycerol-3-phosphate O-acyltransferase 2
  KO
K13509  lysophosphatidate acyltransferase [EC:2.3.1.51]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00561  Glycerolipid metabolism
hsa00564  Glycerophospholipid metabolism
hsa01100  Metabolic pathways
hsa04072  Phospholipase D signaling pathway
hsa04975  Fat digestion and absorption
Module
hsa_M00089  Triacylglycerol biosynthesis
Disease
H00419  Congenital generalized lipodystrophy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    10555 (AGPAT2)
   00564 Glycerophospholipid metabolism
    10555 (AGPAT2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    10555 (AGPAT2)
 09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    10555 (AGPAT2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:hsa01004]
    10555 (AGPAT2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.51  1-acylglycerol-3-phosphate O-acyltransferase
     10555 (AGPAT2)
Lipid biosynthesis proteins [BR:hsa01004]
 Phospholipid acyltransferase
  LPAAT/LPLAT
   10555 (AGPAT2)
SSDB
Motif
Pfam: Acyltransferase
Other DBs
NCBI-GeneID: 10555
NCBI-ProteinID: NP_006403
OMIM: 603100
HGNC: 325
Ensembl: ENSG00000169692
Vega: OTTHUMG00000020936
Pharos: O15120(Tchem)
UniProt: O15120 A0A024R8I7
LinkDB
Position
9q34.3
AA seq 278 aa
MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM
SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK
RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGD
LLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD
VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
NT seq 837 nt   +upstreamnt  +downstreamnt
atggagctgtggccgtgtctggccgcggcgctgctgttgctgctgctgctggtgcagctg
agccgcgcggccgagttctacgccaaggtcgccctgtactgcgcgctgtgcttcacggtg
tccgccgtggcctcgctcgtctgcctgctgcgccacggcggccggacggtggagaacatg
agcatcatcggctggttcgtgcgaagcttcaagtacttttacgggctccgcttcgaggtg
cgggacccgcgcaggctgcaggaggcccgtccctgtgtcatcgtctccaaccaccagagc
atcctggacatgatgggcctcatggaggtccttccggagcgctgcgtgcagatcgccaag
cgggagctgctcttcctggggcccgtgggcctcatcatgtacctcgggggcgtcttcttc
atcaaccggcagcgctctagcactgccatgacagtgatggccgacctgggcgagcgcatg
gtcagggagaacctcaaagtgtggatctatcccgagggtactcgcaacgacaatggggac
ctgctgccttttaagaagggcgccttctacctggcagtccaggcacaggtgcccatcgtc
cccgtggtgtactcttccttctcctccttctacaacaccaagaagaagttcttcacttca
ggaacagtcacagtgcaggtgctggaagccatccccaccagcggcctcactgcggcggac
gtccctgcgctcgtggacacctgccaccgggccatgaggaccaccttcctccacatctcc
aagaccccccaggagaacggggccactgcggggtctggcgtgcagccggcccagtag

KEGG   Homo sapiens (human): 55326
Entry
55326             CDS       T01001                                 

Gene name
AGPAT5, 1AGPAT5, LPAATE
Definition
(RefSeq) 1-acylglycerol-3-phosphate O-acyltransferase 5
  KO
K19007  lysophosphatidiate acyltransferase [EC:2.3.1.51]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00561  Glycerolipid metabolism
hsa00564  Glycerophospholipid metabolism
hsa01100  Metabolic pathways
hsa04072  Phospholipase D signaling pathway
Module
hsa_M00089  Triacylglycerol biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    55326 (AGPAT5)
   00564 Glycerophospholipid metabolism
    55326 (AGPAT5)
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    55326 (AGPAT5)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.51  1-acylglycerol-3-phosphate O-acyltransferase
     55326 (AGPAT5)
SSDB
Motif
Pfam: Acyltransferase Acyltransf_C
Other DBs
NCBI-GeneID: 55326
NCBI-ProteinID: NP_060831
OMIM: 614796
HGNC: 20886
Ensembl: ENSG00000155189
Vega: OTTHUMG00000163656
Pharos: Q9NUQ2(Tbio)
UniProt: Q9NUQ2 A0A024R640
LinkDB
Position
8p23.1
AA seq 364 aa
MLLSLVLHTYSMRYLLPSVVLLGTAPTYVLAWGVWRLLSAFLPARFYQALDDRLYCVYQS
MVLFFFENYTGVQILLYGDLPKNKENIIYLANHQSTVDWIVADILAIRQNALGHVRYVLK
EGLKWLPLYGCYFAQHGGIYVKRSAKFNEKEMRNKLQSYVDAGTPMYLVIFPEGTRYNPE
QTKVLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDCMKNYLDAIYDVTVVYEGKDDGGQ
RRESPTMTEFLCKECPKIHIHIDRIDKKDVPEEQEHMRRWLHERFEIKDKMLIEFYESPD
PERRKRFPGKSVNSKLSIKKTLPSMLILSGLTAGMLMTDAGRKLYVNTWIYGTLLGCLWV
TIKA
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgctgctgtccctggtgctccacacgtactccatgcgctacctgctgcccagcgtcgtg
ctcctgggcacggcgcccacctacgtgttggcctggggggtctggcggctgctctccgcc
ttcctgcccgcccgcttctaccaagcgctggacgaccggctctactgcgtctaccagagc
atggtgctcttcttcttcgagaattacaccggggtccagatattgctatatggagatttg
ccaaaaaataaagaaaatataatatatttagcaaatcatcaaagcacagttgactggatt
gttgctgacatcttggccatcaggcagaatgcgctaggacatgtgcgctacgtgctgaaa
gaagggttaaaatggctgccattgtatgggtgttactttgctcagcatggaggaatctat
gtaaagcgcagtgccaaatttaacgagaaagagatgcgaaacaagttgcagagctacgtg
gacgcaggaactccaatgtatcttgtgatttttccagaaggtacaaggtataatccagag
caaacaaaagtcctttcagctagtcaggcatttgctgcccaacgtggccttgcagtatta
aaacatgtgctaacaccacgaataaaggcaactcacgttgcttttgattgcatgaagaat
tatttagatgcaatttatgatgttacggtggtttatgaagggaaagacgatggagggcag
cgaagagagtcaccgaccatgacggaatttctctgcaaagaatgtccaaaaattcatatt
cacattgatcgtatcgacaaaaaagatgtcccagaagaacaagaacatatgagaagatgg
ctgcatgaacgtttcgaaatcaaagataagatgcttatagaattttatgagtcaccagat
ccagaaagaagaaaaagatttcctgggaaaagtgttaattccaaattaagtatcaagaag
actttaccatcaatgttgatcttaagtggtttgactgcaggcatgcttatgaccgatgct
ggaaggaagctgtatgtgaacacctggatatatggaaccctacttggctgcctgtgggtt
actattaaagcatag

KEGG   Homo sapiens (human): 56894
Entry
56894             CDS       T01001                                 

Gene name
AGPAT3, 1-AGPAT_3, LPAAT-GAMMA1, LPAAT3
Definition
(RefSeq) 1-acylglycerol-3-phosphate O-acyltransferase 3
  KO
K13523  lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00561  Glycerolipid metabolism
hsa00564  Glycerophospholipid metabolism
hsa01100  Metabolic pathways
hsa04072  Phospholipase D signaling pathway
Module
hsa_M00089  Triacylglycerol biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    56894 (AGPAT3)
   00564 Glycerophospholipid metabolism
    56894 (AGPAT3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    56894 (AGPAT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:hsa01004]
    56894 (AGPAT3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.51  1-acylglycerol-3-phosphate O-acyltransferase
     56894 (AGPAT3)
    2.3.1.-  
     56894 (AGPAT3)
Lipid biosynthesis proteins [BR:hsa01004]
 Phospholipid acyltransferase
  LPAAT/LPLAT
   56894 (AGPAT3)
SSDB
Motif
Pfam: Acyltransf_C Acyltransferase
Other DBs
NCBI-GeneID: 56894
NCBI-ProteinID: NP_001032642
OMIM: 614794
HGNC: 326
Ensembl: ENSG00000160216
Vega: OTTHUMG00000086892
Pharos: Q9NRZ7(Tbio)
UniProt: Q9NRZ7
LinkDB
Position
21q22.3
AA seq 376 aa
MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQ
LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV
LAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRF
TETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSL
LGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFK
PARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTE
IEKGSSYGNQEFKKKE
NT seq 1131 nt   +upstreamnt  +downstreamnt
atgggcctgctggccttcctgaagacccagttcgtgctgcacctgctggtcggctttgtc
ttcgtggtgagtggtctggtcatcaacttcgtccagctgtgcacgctggcgctctggccg
gtcagcaagcagctctaccgccgcctcaactgccgcctcgcctactcactctggagccaa
ctggtcatgctgctggagtggtggtcctgcacggagtgtacactgttcacggaccaggcc
acggtagagcgctttgggaaggagcacgcagtcatcatcctcaaccacaacttcgagatc
gacttcctctgtgggtggaccatgtgtgagcgcttcggagtgctggggagctccaaggtc
ctcgctaagaaggagctgctctacgtgcccctcatcggctggacgtggtactttctggag
attgtgttctgcaagcggaagtgggaggaggaccgggacaccgtggtcgaagggctgagg
cgcctgtcggactaccccgagtacatgtggtttctcctgtactgcgaggggacgcgcttc
acggagaccaagcaccgcgttagcatggaggtggcggctgctaaggggcttcctgtcctc
aagtaccacctgctgccgcggaccaagggcttcaccaccgcagtcaagtgcctccggggg
acagtcgcagctgtctatgatgtaaccctgaacttcagaggaaacaagaacccgtccctg
ctggggatcctctacgggaagaagtacgaggcggacatgtgcgtgaggagatttcctctg
gaagacatcccgctggatgaaaaggaagcagctcagtggcttcataaactgtaccaggag
aaggacgcgctccaggagatatataatcagaagggcatgtttccaggggagcagtttaag
cctgcccggaggccgtggaccctcctgaacttcctgtcctgggccaccattctcctgtct
cccctcttcagttttgtcttgggcgtctttgccagcggatcacctctcctgatcctgact
ttcttggggtttgtgggagcagcttcctttggagttcgcagactgataggagtaactgag
atagaaaaaggctccagctacggaaaccaagagtttaagaaaaaggaataa

KEGG   Homo sapiens (human): 56895
Entry
56895             CDS       T01001                                 

Gene name
AGPAT4, 1-AGPAT4, LPAAT-delta, dJ473J16.2
Definition
(RefSeq) 1-acylglycerol-3-phosphate O-acyltransferase 4
  KO
K13523  lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00561  Glycerolipid metabolism
hsa00564  Glycerophospholipid metabolism
hsa01100  Metabolic pathways
hsa04072  Phospholipase D signaling pathway
Module
hsa_M00089  Triacylglycerol biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    56895 (AGPAT4)
   00564 Glycerophospholipid metabolism
    56895 (AGPAT4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    56895 (AGPAT4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:hsa01004]
    56895 (AGPAT4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.51  1-acylglycerol-3-phosphate O-acyltransferase
     56895 (AGPAT4)
    2.3.1.-  
     56895 (AGPAT4)
Lipid biosynthesis proteins [BR:hsa01004]
 Phospholipid acyltransferase
  LPAAT/LPLAT
   56895 (AGPAT4)
SSDB
Motif
Pfam: Acyltransf_C Acyltransferase
Other DBs
NCBI-GeneID: 56895
NCBI-ProteinID: NP_064518
OMIM: 614795
HGNC: 20885
Ensembl: ENSG00000026652
Vega: OTTHUMG00000015966
Pharos: Q9NRZ5(Tbio)
UniProt: Q9NRZ5
LinkDB
Position
6q26
AA seq 378 aa
MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQ
LVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKV
LAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRF
TEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTL
LGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMV
PPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTE
IDKGSAYGNSDSKQKLND
NT seq 1137 nt   +upstreamnt  +downstreamnt
atggacctcgcgggactgctgaagtctcagttcctgtgccacctggtcttctgctacgtc
tttattgcctcagggctaatcatcaacaccattcagctcttcactctcctcctctggccc
attaacaagcagctcttccggaagatcaactgcagactgtcctattgcatctcaagccag
ctggtgatgctgctggagtggtggtcgggcacggaatgcaccatcttcacggacccgcgc
gcctacctcaagtatgggaaggaaaatgccatcgtggttctcaaccacaagtttgaaatt
gactttctgtgtggctggagcctgtccgaacgctttgggctgttagggggctccaaggtc
ctggccaagaaagagctggcctatgtcccaattatcggctggatgtggtacttcaccgag
atggtcttctgttcgcgcaagtgggagcaggatcgcaagacggttgccaccagtttgcag
cacctccgggactaccccgagaagtattttttcctgattcactgtgagggcacacggttc
acggagaagaagcatgagatcagcatgcaggtggcccgggccaaggggctgcctcgcctc
aagcatcacctgttgccacgaaccaagggcttcgccatcaccgtgaggagcttgagaaat
gtagtttcagctgtatatgactgtacactcaatttcagaaataatgaaaatccaacactg
ctgggagtcctaaacggaaagaaataccatgcagatttgtatgttaggaggatcccactg
gaagacatccctgaagacgatgacgagtgctcggcctggctgcacaagctctaccaggag
aaggatgcctttcaggaggagtactacaggacgggcaccttcccagagacgcccatggtg
cccccccggcggccctggaccctcgtgaactggctgttttgggcctcgctggtgctctac
cctttcttccagttcctggtcagcatgatcaggagcgggtcttccctgacgctggccagc
ttcatcctcgtcttctttgtggcctccgtgggagttcgatggatgattggtgtgacggaa
attgacaagggctctgcctacggcaactctgacagcaagcagaaactgaatgactga

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