KEGG   Homo sapiens (human): 10681Help
Entry
10681             CDS       T01001                                 

Gene name
GNB5, GB5, IDDCA, LADCI
Definition
(RefSeq) G protein subunit beta 5
  KO
K04539  guanine nucleotide-binding protein subunit beta-5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    10681 (GNB5)
   04371 Apelin signaling pathway
    10681 (GNB5)
   04151 PI3K-Akt signaling pathway
    10681 (GNB5)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    10681 (GNB5)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    10681 (GNB5)
  09156 Nervous system
   04724 Glutamatergic synapse
    10681 (GNB5)
   04727 GABAergic synapse
    10681 (GNB5)
   04725 Cholinergic synapse
    10681 (GNB5)
   04728 Dopaminergic synapse
    10681 (GNB5)
   04726 Serotonergic synapse
    10681 (GNB5)
   04723 Retrograde endocannabinoid signaling
    10681 (GNB5)
  09159 Environmental adaptation
   04713 Circadian entrainment
    10681 (GNB5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    10681 (GNB5)
  09165 Substance dependence
   05032 Morphine addiction
    10681 (GNB5)
   05034 Alcoholism
    10681 (GNB5)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    10681 (GNB5)
   05163 Human cytomegalovirus infection
    10681 (GNB5)
   05167 Kaposi sarcoma-associated herpesvirus infection
    10681 (GNB5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    10681 (GNB5)
   04031 GTP-binding proteins [BR:hsa04031]
    10681 (GNB5)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   10681 (GNB5)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Beta Subunits
   Beta [OT]
    10681 (GNB5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: WD40 ANAPC4_WD40 WD40_like Atg14
Motif
Other DBs
NCBI-GeneID: 10681
NCBI-ProteinID: NP_057278
OMIM: 604447
HGNC: 4401
Ensembl: ENSG00000069966
Vega: OTTHUMG00000131892
Pharos: O14775(Tbio)
UniProt: O14775 A0A024R5V3
LinkDB All DBs
Position
15q21.2
AA seq 395 aa AA seqDB search
MCDQTFLVNVFGSCDKCFKQRALRPVFKKSQQLSYCSTCAEIMATEGLHENETLASLKSE
AESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRI
VSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDK
NENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADV
LCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGS
DDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRV
SILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA
NT seq 1188 nt NT seq  +upstreamnt  +downstreamnt
atgtgtgatcagacctttctcgttaatgtatttggctcatgtgacaaatgtttcaaacaa
cgagctctgagaccagttttcaagaagtctcaacaactcagctactgttcaacatgtgca
gaaattatggcaaccgaggggctgcacgagaacgagacgctggcgtcgctgaagagcgag
gccgagagcctcaagggcaagctggaggaggagcgagccaagctgcacgatgtggagctg
caccaggtggcggagcgggtggaggccctggggcagtttgtcatgaagaccagaaggacc
ctcaaaggccacgggaacaaagtcctgtgcatggactggtgcaaagataagaggaggatc
gtgagctcgtcacaggatgggaaggtgatcgtgtgggattccttcaccacaaacaaggag
cacgcggtcaccatgccctgcacgtgggtgatggcatgtgcttatgccccatcgggatgt
gccattgcttgtggtggtttggataataagtgttctgtgtaccccttgacgtttgacaaa
aatgaaaacatggctgccaaaaagaagtctgttgctatgcacaccaactacctgtcggcc
tgcagcttcaccaactctgacatgcagatcctgacagcgagcggcgatggcacatgtgcc
ctgtgggacgtggagagcgggcagctgctgcagagcttccacggacatggggctgacgtc
ctctgcttggacctggccccctcagaaactggaaacaccttcgtgtctgggggatgtgac
aagaaagccatggtgtgggacatgcgctccggccagtgcgtgcaggcctttgaaacacat
gaatctgacatcaacagtgtccggtactaccccagtggagatgcctttgcttcagggtca
gatgacgctacgtgtcgcctctatgacctgcgggcagatagggaggttgccatctattcc
aaagaaagcatcatatttggagcatccagcgtggacttctccctcagtggtcgcctgctg
tttgctggatacaatgattacactatcaacgtctgggatgttctcaaagggtcccgggtc
tccatcctgtttggacatgaaaaccgcgttagcactctacgagtttcccccgatgggact
gctttctgctctggatcatgggatcataccctcagagtctgggcctaa

KEGG   Homo sapiens (human): 2782Help
Entry
2782              CDS       T01001                                 

Gene name
GNB1, MRD42
Definition
(RefSeq) G protein subunit beta 1
  KO
K04536  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04740  Olfactory transduction
hsa04744  Phototransduction
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Disease
H00773  Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    2782 (GNB1)
   04371 Apelin signaling pathway
    2782 (GNB1)
   04151 PI3K-Akt signaling pathway
    2782 (GNB1)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    2782 (GNB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2782 (GNB1)
  09156 Nervous system
   04724 Glutamatergic synapse
    2782 (GNB1)
   04727 GABAergic synapse
    2782 (GNB1)
   04725 Cholinergic synapse
    2782 (GNB1)
   04728 Dopaminergic synapse
    2782 (GNB1)
   04726 Serotonergic synapse
    2782 (GNB1)
   04723 Retrograde endocannabinoid signaling
    2782 (GNB1)
  09157 Sensory system
   04744 Phototransduction
    2782 (GNB1)
   04740 Olfactory transduction
    2782 (GNB1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2782 (GNB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2782 (GNB1)
  09165 Substance dependence
   05032 Morphine addiction
    2782 (GNB1)
   05034 Alcoholism
    2782 (GNB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    2782 (GNB1)
   05163 Human cytomegalovirus infection
    2782 (GNB1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2782 (GNB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2782 (GNB1)
   04031 GTP-binding proteins [BR:hsa04031]
    2782 (GNB1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   2782 (GNB1)
  Exosomal proteins of colorectal cancer cells
   2782 (GNB1)
  Exosomal proteins of melanoma cells
   2782 (GNB1)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Beta Subunits
   Beta [OT]
    2782 (GNB1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: WD40 ANAPC4_WD40 WD40_like eIF2A Myc-LZ PQQ_2 CALM_bind
Motif
Other DBs
NCBI-GeneID: 2782
NCBI-ProteinID: NP_001269468
OMIM: 139380
HGNC: 4396
Ensembl: ENSG00000078369
Vega: OTTHUMG00000000940
Pharos: P62873(Tbio)
UniProt: P62873 A0A024R056
LinkDB All DBs
Structure
PDB: 

Position
1p36.33
AA seq 340 aa AA seqDB search
MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYA
MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNI
CSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTF
TGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL
KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
NT seq 1023 nt NT seq  +upstreamnt  +downstreamnt
atgagtgagcttgaccagttacggcaggaggccgagcaacttaagaaccagattcgagac
gccaggaaagcatgtgcagatgcaactctctctcagatcacaaacaacatcgacccagtg
ggaagaatccaaatgcgcacgaggaggacactgcgggggcacctggccaagatctacgcc
atgcactggggcacagactccaggcttctcgtcagtgcctcgcaggatggtaaacttatc
atctgggacagctacaccaccaacaaggtccacgccatccctctgcgctcctcctgggtc
atgacctgtgcatatgccccttctgggaactatgtggcctgcggtggcctggataacatt
tgctccatttacaatctgaaaactcgtgaggggaacgtgcgcgtgagtcgtgagctggca
ggacacacaggttacctgtcctgctgccgattcctggatgacaatcagatcgtcaccagc
tctggagacaccacgtgtgccctgtgggacatcgagaccggccagcagacgaccacgttt
accggacacactggagatgtcatgagcctttctcttgctcctgacaccagactgttcgtc
tctggtgcttgtgatgcttcagccaaactctgggatgtgcgagaaggcatgtgccggcag
accttcactggccacgagtctgacatcaatgccatttgcttctttccaaatggcaatgca
tttgccactggctcagacgacgccacctgcaggctgtttgaccttcgtgctgaccaggag
ctcatgacttactcccatgacaacatcatctgcgggatcacctctgtctccttctccaag
agcgggcgcctcctccttgctgggtacgacgacttcaactgcaacgtctgggatgcactc
aaagccgaccgggcaggtgtcttggctgggcatgacaaccgcgtcagctgcctgggcgtg
actgacgatggcatggctgtggcgacagggtcctgggatagcttcctcaagatctggaac
taa

KEGG   Homo sapiens (human): 2783Help
Entry
2783              CDS       T01001                                 

Gene name
GNB2
Definition
(RefSeq) G protein subunit beta 2
  KO
K04537  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    2783 (GNB2)
   04371 Apelin signaling pathway
    2783 (GNB2)
   04151 PI3K-Akt signaling pathway
    2783 (GNB2)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    2783 (GNB2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2783 (GNB2)
  09156 Nervous system
   04724 Glutamatergic synapse
    2783 (GNB2)
   04727 GABAergic synapse
    2783 (GNB2)
   04725 Cholinergic synapse
    2783 (GNB2)
   04728 Dopaminergic synapse
    2783 (GNB2)
   04726 Serotonergic synapse
    2783 (GNB2)
   04723 Retrograde endocannabinoid signaling
    2783 (GNB2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2783 (GNB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2783 (GNB2)
  09165 Substance dependence
   05032 Morphine addiction
    2783 (GNB2)
   05034 Alcoholism
    2783 (GNB2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    2783 (GNB2)
   05163 Human cytomegalovirus infection
    2783 (GNB2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2783 (GNB2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2783 (GNB2)
   04031 GTP-binding proteins [BR:hsa04031]
    2783 (GNB2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   2783 (GNB2)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Beta Subunits
   Beta [OT]
    2783 (GNB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: WD40 ANAPC4_WD40 WD40_like CALM_bind
Motif
Other DBs
NCBI-GeneID: 2783
NCBI-ProteinID: NP_005264
OMIM: 139390
HGNC: 4398
Ensembl: ENSG00000172354
Vega: OTTHUMG00000137419
Pharos: P62879(Tbio)
UniProt: P62879 Q6FHM2
LinkDB All DBs
Position
7q22.1
AA seq 340 aa AA seqDB search
MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGRIQMRTRRTLRGHLAKIYA
MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNI
CSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGF
AGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYA
FTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM
KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
NT seq 1023 nt NT seq  +upstreamnt  +downstreamnt
atgagtgagctggagcaactgagacaggaggccgagcagctccggaaccagatccgggat
gcccgaaaagcatgtggggactcaacactgacccagatcacagctgggctggacccagtg
gggagaatccagatgaggacccggaggaccctccgtgggcacctggcaaagatctatgcc
atgcactgggggaccgactcaaggctgctggtcagcgcctcccaggatgggaagctcatc
atctgggacagctacaccaccaacaaggtccacgccatcccgctgcgctcctcctgggta
atgacctgtgcctacgcgccctcagggaactttgtggcctgtggggggttggacaacatc
tgctccatctacagcctcaagacccgcgagggcaacgtcagggtcagccgggagctgcct
ggccacactgggtacctgtcgtgttgccgcttcctggatgacaaccaaatcatcaccagc
tctggggataccacctgtgccctgtgggacattgagacaggccagcagacagtgggtttt
gctggacacagtggggatgtgatgtccctgtccctggcccccgatggccgcacgtttgtg
tcaggcgcctgtgatgcctctatcaagctgtgggacgtgcgggattccatgtgccgacag
accttcatcggccatgaatccgacatcaatgcagtggctttcttccccaacggctacgcc
ttcaccaccggctctgacgacgccacgtgccgcctcttcgacctgcgggccgatcaggag
ctcctcatgtactcccatgacaacatcatctgtggcatcacctctgttgccttctcgcgc
agcggacggctgctgctcgctggctacgacgacttcaactgcaacatctgggatgccatg
aagggcgaccgtgcaggagtcctcgctggccacgacaaccgcgtgagctgcctcggggtc
accgacgatggcatggctgtggccacgggctcctgggactccttcctcaagatctggaac
taa

KEGG   Homo sapiens (human): 2784Help
Entry
2784              CDS       T01001                                 

Gene name
GNB3, CSNB1H
Definition
(RefSeq) G protein subunit beta 3
  KO
K07825  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04742  Taste transduction
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Disease
H00787  Congenital stationary night blindness
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    2784 (GNB3)
   04371 Apelin signaling pathway
    2784 (GNB3)
   04151 PI3K-Akt signaling pathway
    2784 (GNB3)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    2784 (GNB3)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2784 (GNB3)
  09156 Nervous system
   04724 Glutamatergic synapse
    2784 (GNB3)
   04727 GABAergic synapse
    2784 (GNB3)
   04725 Cholinergic synapse
    2784 (GNB3)
   04728 Dopaminergic synapse
    2784 (GNB3)
   04726 Serotonergic synapse
    2784 (GNB3)
   04723 Retrograde endocannabinoid signaling
    2784 (GNB3)
  09157 Sensory system
   04742 Taste transduction
    2784 (GNB3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2784 (GNB3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2784 (GNB3)
  09165 Substance dependence
   05032 Morphine addiction
    2784 (GNB3)
   05034 Alcoholism
    2784 (GNB3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    2784 (GNB3)
   05163 Human cytomegalovirus infection
    2784 (GNB3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2784 (GNB3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2784 (GNB3)
   04031 GTP-binding proteins [BR:hsa04031]
    2784 (GNB3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   2784 (GNB3)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Beta Subunits
   Beta [OT]
    2784 (GNB3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: WD40 ANAPC4_WD40 eIF2A WD40_like Cytochrom_D1 Myc-LZ
Motif
Other DBs
NCBI-GeneID: 2784
NCBI-ProteinID: NP_002066
OMIM: 139130
HGNC: 4400
Ensembl: ENSG00000111664
Vega: OTTHUMG00000168517
Pharos: P16520(Tbio)
UniProt: P16520 F1T0G5
LinkDB All DBs
Position
12p13.31
AA seq 340 aa AA seqDB search
MGEMEQLRQEAEQLKKQIADARKACADVTLAELVSGLEVVGRVQMRTRRTLRGHLAKIYA
MHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNM
CSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVF
VGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEA
ICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSM
KSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN
NT seq 1023 nt NT seq  +upstreamnt  +downstreamnt
atgggggagatggagcaactgcgtcaggaagcggagcagctcaagaagcagattgcagat
gccaggaaagcctgtgctgacgttactctggcagagctggtgtctggcctagaggtggtg
ggacgagtccagatgcggacgcggcggacgttaaggggacacctggccaagatttacgcc
atgcactgggccactgattctaagctgctggtaagtgcctcgcaagatgggaagctgatc
gtgtgggacagctacaccaccaacaaggtgcacgccatcccactgcgctcctcctgggtc
atgacctgtgcctatgccccatcagggaactttgtggcatgtggggggctggacaacatg
tgttccatctacaacctcaaatcccgtgagggcaatgtcaaggtcagccgggagctttct
gctcacacaggttatctctcctgctgccgcttcctggatgacaacaatattgtgaccagc
tcgggggacaccacgtgtgccttgtgggacattgagactgggcagcagaagactgtattt
gtgggacacacgggtgactgcatgagcctggctgtgtctcctgacttcaatctcttcatt
tcgggggcctgtgatgccagtgccaagctctgggatgtgcgagaggggacctgccgtcag
actttcactggccacgagtcggacatcaacgccatctgtttcttccccaatggagaggcc
atctgcacgggctcggatgacgcttcctgccgcttgtttgacctgcgggcagaccaggag
ctgatctgcttctcccacgagagcatcatctgcggcatcacgtccgtggccttctccctc
agtggccgcctactattcgctggctacgacgacttcaactgcaatgtctgggactccatg
aagtctgagcgtgtgggcatcctctctggccacgataacagggtgagctgcctgggagtc
acagctgacgggatggctgtggccacaggttcctgggacagcttcctcaaaatctggaac
tga

KEGG   Homo sapiens (human): 2785Help
Entry
2785              CDS       T01001                                 

Gene name
GNG3
Definition
(RefSeq) G protein subunit gamma 3
  KO
K04540  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    2785 (GNG3)
   04371 Apelin signaling pathway
    2785 (GNG3)
   04151 PI3K-Akt signaling pathway
    2785 (GNG3)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    2785 (GNG3)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2785 (GNG3)
  09156 Nervous system
   04724 Glutamatergic synapse
    2785 (GNG3)
   04727 GABAergic synapse
    2785 (GNG3)
   04725 Cholinergic synapse
    2785 (GNG3)
   04728 Dopaminergic synapse
    2785 (GNG3)
   04726 Serotonergic synapse
    2785 (GNG3)
   04723 Retrograde endocannabinoid signaling
    2785 (GNG3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2785 (GNG3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2785 (GNG3)
  09165 Substance dependence
   05032 Morphine addiction
    2785 (GNG3)
   05034 Alcoholism
    2785 (GNG3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    2785 (GNG3)
   05163 Human cytomegalovirus infection
    2785 (GNG3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2785 (GNG3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:hsa04031]
    2785 (GNG3)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    2785 (GNG3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma
Motif
Other DBs
NCBI-GeneID: 2785
NCBI-ProteinID: NP_036334
OMIM: 608941
HGNC: 4405
Ensembl: ENSG00000162188
Vega: OTTHUMG00000167560
Pharos: P63215(Tdark)
UniProt: P63215
LinkDB All DBs
Position
11q12.3
AA seq 75 aa AA seqDB search
MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT
SENPFREKKFFCALL
NT seq 228 nt NT seq  +upstreamnt  +downstreamnt
atgaaaggtgagaccccggtgaacagcactatgagtattgggcaagcacgcaagatggtg
gaacagcttaagattgaagccagcttgtgtcggataaaggtgtccaaggcagcagcagac
ctgatgacttactgtgatgcccacgcctgtgaggatcccctcatcacccctgtgcccact
tcggagaaccccttccgggagaagaagttcttctgtgctctcctctga

KEGG   Homo sapiens (human): 2786Help
Entry
2786              CDS       T01001                                 

Gene name
GNG4
Definition
(RefSeq) G protein subunit gamma 4
  KO
K04541  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    2786 (GNG4)
   04371 Apelin signaling pathway
    2786 (GNG4)
   04151 PI3K-Akt signaling pathway
    2786 (GNG4)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    2786 (GNG4)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2786 (GNG4)
  09156 Nervous system
   04724 Glutamatergic synapse
    2786 (GNG4)
   04727 GABAergic synapse
    2786 (GNG4)
   04725 Cholinergic synapse
    2786 (GNG4)
   04728 Dopaminergic synapse
    2786 (GNG4)
   04726 Serotonergic synapse
    2786 (GNG4)
   04723 Retrograde endocannabinoid signaling
    2786 (GNG4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2786 (GNG4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2786 (GNG4)
  09165 Substance dependence
   05032 Morphine addiction
    2786 (GNG4)
   05034 Alcoholism
    2786 (GNG4)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    2786 (GNG4)
   05163 Human cytomegalovirus infection
    2786 (GNG4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2786 (GNG4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:hsa04031]
    2786 (GNG4)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    2786 (GNG4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma ATP-synt_F Adeno_PV
Motif
Other DBs
NCBI-GeneID: 2786
NCBI-ProteinID: NP_001092191
OMIM: 604388
HGNC: 4407
Ensembl: ENSG00000168243
Vega: OTTHUMG00000040740
Pharos: P50150(Tdark)
UniProt: P50150 B1APZ0
LinkDB All DBs
Position
1q42.3
AA seq 75 aa AA seqDB search
MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPA
SENPFREKKFFCTIL
NT seq 228 nt NT seq  +upstreamnt  +downstreamnt
atgaaagagggcatgtctaataacagcaccactagcatctcccaagccaggaaagctgtg
gagcagctaaagatggaagcctgtatggacagggtcaaggtctcccaggcagctgcggac
ctcctggcctactgtgaagctcacgtgcgggaagatcctctcatcattccagtgcctgca
tcagaaaacccctttcgcgagaagaagttcttttgtaccattctctaa

KEGG   Homo sapiens (human): 2787Help
Entry
2787              CDS       T01001                                 

Gene name
GNG5
Definition
(RefSeq) G protein subunit gamma 5
  KO
K04542  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    2787 (GNG5)
   04371 Apelin signaling pathway
    2787 (GNG5)
   04151 PI3K-Akt signaling pathway
    2787 (GNG5)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    2787 (GNG5)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2787 (GNG5)
  09156 Nervous system
   04724 Glutamatergic synapse
    2787 (GNG5)
   04727 GABAergic synapse
    2787 (GNG5)
   04725 Cholinergic synapse
    2787 (GNG5)
   04728 Dopaminergic synapse
    2787 (GNG5)
   04726 Serotonergic synapse
    2787 (GNG5)
   04723 Retrograde endocannabinoid signaling
    2787 (GNG5)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2787 (GNG5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2787 (GNG5)
  09165 Substance dependence
   05032 Morphine addiction
    2787 (GNG5)
   05034 Alcoholism
    2787 (GNG5)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    2787 (GNG5)
   05163 Human cytomegalovirus infection
    2787 (GNG5)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2787 (GNG5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2787 (GNG5)
   04031 GTP-binding proteins [BR:hsa04031]
    2787 (GNG5)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   2787 (GNG5)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    2787 (GNG5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma FtsX_ECD DUF3338 Suv3_N
Motif
Other DBs
NCBI-GeneID: 2787
NCBI-ProteinID: NP_005265
OMIM: 600874
HGNC: 4408
Ensembl: ENSG00000174021
Vega: OTTHUMG00000009858
Pharos: P63218(Tbio)
UniProt: P63218
LinkDB All DBs
Position
1p22.3
AA seq 68 aa AA seqDB search
MSGSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSSTNPFR
PQKVCSFL
NT seq 207 nt NT seq  +upstreamnt  +downstreamnt
atgtctggctcctccagcgtcgccgctatgaagaaagtggttcaacagctccggctggag
gccggactcaaccgcgtaaaagtttcccaggcagctgcagacttgaaacagttctgtctg
cagaatgctcaacatgaccctctgctgactggagtatcttcaagtacaaatcccttcaga
ccccagaaagtctgttcctttttgtag

KEGG   Homo sapiens (human): 2788Help
Entry
2788              CDS       T01001                                 

Gene name
GNG7
Definition
(RefSeq) G protein subunit gamma 7
  KO
K04543  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04740  Olfactory transduction
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    2788 (GNG7)
   04371 Apelin signaling pathway
    2788 (GNG7)
   04151 PI3K-Akt signaling pathway
    2788 (GNG7)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    2788 (GNG7)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2788 (GNG7)
  09156 Nervous system
   04724 Glutamatergic synapse
    2788 (GNG7)
   04727 GABAergic synapse
    2788 (GNG7)
   04725 Cholinergic synapse
    2788 (GNG7)
   04728 Dopaminergic synapse
    2788 (GNG7)
   04726 Serotonergic synapse
    2788 (GNG7)
   04723 Retrograde endocannabinoid signaling
    2788 (GNG7)
  09157 Sensory system
   04740 Olfactory transduction
    2788 (GNG7)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2788 (GNG7)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2788 (GNG7)
  09165 Substance dependence
   05032 Morphine addiction
    2788 (GNG7)
   05034 Alcoholism
    2788 (GNG7)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    2788 (GNG7)
   05163 Human cytomegalovirus infection
    2788 (GNG7)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2788 (GNG7)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2788 (GNG7)
   04031 GTP-binding proteins [BR:hsa04031]
    2788 (GNG7)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   2788 (GNG7)
  Exosomal proteins of other body fluids (saliva and urine)
   2788 (GNG7)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    2788 (GNG7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma FtsX_ECD CP12
Motif
Other DBs
NCBI-GeneID: 2788
NCBI-ProteinID: NP_443079
OMIM: 604430
HGNC: 4410
Ensembl: ENSG00000176533
Vega: OTTHUMG00000180435
Pharos: O60262(Tdark)
UniProt: O60262
LinkDB All DBs
Position
19p13.3
AA seq 68 aa AA seqDB search
MSATNNIAQARKLVEQLRIEAGIERIKVSKAASDLMSYCEQHARNDPLLVGVPASENPFK
DKKPCIIL
NT seq 207 nt NT seq  +upstreamnt  +downstreamnt
atgtcagccactaacaacatagcccaggcccggaagctggtggaacagctacgcatagaa
gccgggattgagcgcatcaaggtctccaaagcggcgtctgacctcatgagctactgtgag
caacatgcccggaacgaccccctgctggtcggagtccctgcctcggagaacccctttaag
gacaagaaaccttgtattattttataa

KEGG   Homo sapiens (human): 2790Help
Entry
2790              CDS       T01001                                 

Gene name
GNG10
Definition
(RefSeq) G protein subunit gamma 10
  KO
K04545  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    2790 (GNG10)
   04371 Apelin signaling pathway
    2790 (GNG10)
   04151 PI3K-Akt signaling pathway
    2790 (GNG10)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    2790 (GNG10)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2790 (GNG10)
  09156 Nervous system
   04724 Glutamatergic synapse
    2790 (GNG10)
   04727 GABAergic synapse
    2790 (GNG10)
   04725 Cholinergic synapse
    2790 (GNG10)
   04728 Dopaminergic synapse
    2790 (GNG10)
   04726 Serotonergic synapse
    2790 (GNG10)
   04723 Retrograde endocannabinoid signaling
    2790 (GNG10)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2790 (GNG10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2790 (GNG10)
  09165 Substance dependence
   05032 Morphine addiction
    2790 (GNG10)
   05034 Alcoholism
    2790 (GNG10)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    2790 (GNG10)
   05163 Human cytomegalovirus infection
    2790 (GNG10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2790 (GNG10)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:hsa04031]
    2790 (GNG10)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    2790 (GNG10)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma FtsX_ECD
Motif
Other DBs
NCBI-GeneID: 2790
NCBI-ProteinID: NP_001017998
OMIM: 604389
HGNC: 4402
Ensembl: ENSG00000242616
Vega: OTTHUMG00000157193
Pharos: P50151(Tdark)
UniProt: P50151 A0A024R156
LinkDB All DBs
Position
9q31.3
AA seq 68 aa AA seqDB search
MSSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFR
EPRSCALL
NT seq 207 nt NT seq  +upstreamnt  +downstreamnt
atgtcctccggggctagcgcgagcgccctgcagcgcttggtagagcagctcaagttggag
gctggcgtggagaggatcaaggtctctcaggcagctgcagagcttcaacagtactgtatg
cagaatgcctgcaaggatgccctgctggtgggtgttccagctggaagtaaccccttccgg
gagcctagatcctgtgctttactctga

KEGG   Homo sapiens (human): 2791Help
Entry
2791              CDS       T01001                                 

Gene name
GNG11, GNGT11
Definition
(RefSeq) G protein subunit gamma 11
  KO
K04546  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    2791 (GNG11)
   04371 Apelin signaling pathway
    2791 (GNG11)
   04151 PI3K-Akt signaling pathway
    2791 (GNG11)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    2791 (GNG11)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2791 (GNG11)
  09156 Nervous system
   04724 Glutamatergic synapse
    2791 (GNG11)
   04727 GABAergic synapse
    2791 (GNG11)
   04725 Cholinergic synapse
    2791 (GNG11)
   04728 Dopaminergic synapse
    2791 (GNG11)
   04726 Serotonergic synapse
    2791 (GNG11)
   04723 Retrograde endocannabinoid signaling
    2791 (GNG11)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2791 (GNG11)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2791 (GNG11)
  09165 Substance dependence
   05032 Morphine addiction
    2791 (GNG11)
   05034 Alcoholism
    2791 (GNG11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    2791 (GNG11)
   05163 Human cytomegalovirus infection
    2791 (GNG11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2791 (GNG11)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:hsa04031]
    2791 (GNG11)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    2791 (GNG11)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma HAUS5 DUF2508 COG2 Macoilin Cep57_CLD_2
Motif
Other DBs
NCBI-GeneID: 2791
NCBI-ProteinID: NP_004117
OMIM: 604390
HGNC: 4403
Ensembl: ENSG00000127920
Vega: OTTHUMG00000023411
Pharos: P61952(Tdark)
UniProt: P61952 Q53Y01
LinkDB All DBs
Position
7q21.3
AA seq 73 aa AA seqDB search
MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED
KNPFKEKGSCVIS
NT seq 222 nt NT seq  +upstreamnt  +downstreamnt
atgcctgcccttcacatcgaagatttgccagagaaggaaaaactgaaaatggaagttgag
cagcttcgcaaagaagtgaagttgcagagacaacaagtgtctaaatgttctgaagaaata
aagaactatattgaagaacgttctggagaggatcctctagtaaagggaattccagaagac
aagaacccctttaaagaaaaaggcagctgtgttatttcataa

KEGG   Homo sapiens (human): 2792Help
Entry
2792              CDS       T01001                                 

Gene name
GNGT1, GNG1
Definition
(RefSeq) G protein subunit gamma transducin 1
  KO
K04548  guanine nucleotide-binding protein G(T) subunit gamma-T1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04744  Phototransduction
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    2792 (GNGT1)
   04371 Apelin signaling pathway
    2792 (GNGT1)
   04151 PI3K-Akt signaling pathway
    2792 (GNGT1)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    2792 (GNGT1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2792 (GNGT1)
  09156 Nervous system
   04724 Glutamatergic synapse
    2792 (GNGT1)
   04727 GABAergic synapse
    2792 (GNGT1)
   04725 Cholinergic synapse
    2792 (GNGT1)
   04728 Dopaminergic synapse
    2792 (GNGT1)
   04726 Serotonergic synapse
    2792 (GNGT1)
   04723 Retrograde endocannabinoid signaling
    2792 (GNGT1)
  09157 Sensory system
   04744 Phototransduction
    2792 (GNGT1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2792 (GNGT1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2792 (GNGT1)
  09165 Substance dependence
   05032 Morphine addiction
    2792 (GNGT1)
   05034 Alcoholism
    2792 (GNGT1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    2792 (GNGT1)
   05163 Human cytomegalovirus infection
    2792 (GNGT1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2792 (GNGT1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:hsa04031]
    2792 (GNGT1)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    2792 (GNGT1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma DUF2508
Motif
Other DBs
NCBI-GeneID: 2792
NCBI-ProteinID: NP_001316355
OMIM: 189970
HGNC: 4411
Ensembl: ENSG00000127928
Vega: OTTHUMG00000022908
Pharos: P63211(Tbio)
UniProt: P63211
LinkDB All DBs
Position
7q21.3
AA seq 74 aa AA seqDB search
MPVINIEDLTEKDKLKMEVDQLKKEVTLERMLVSKCCEEVRDYVEERSGEDPLVKGIPED
KNPFKELKGGCVIS
NT seq 225 nt NT seq  +upstreamnt  +downstreamnt
atgccagtaatcaatattgaggacctgacagaaaaggacaaattgaagatggaagttgac
cagctcaagaaagaagtgacactggaaagaatgctagtttccaaatgttgtgaagaagta
agagattacgttgaagaacgatctggcgaggatccactggtaaagggcatcccagaggac
aaaaatcccttcaaggagctcaaaggaggctgtgtgatttcataa

KEGG   Homo sapiens (human): 2793Help
Entry
2793              CDS       T01001                                 

Gene name
GNGT2, G-GAMMA-8, G-GAMMA-C, GNG8, GNG9, GNGT8
Definition
(RefSeq) G protein subunit gamma transducin 2
  KO
K04549  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    2793 (GNGT2)
   04371 Apelin signaling pathway
    2793 (GNGT2)
   04151 PI3K-Akt signaling pathway
    2793 (GNGT2)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    2793 (GNGT2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2793 (GNGT2)
  09156 Nervous system
   04724 Glutamatergic synapse
    2793 (GNGT2)
   04727 GABAergic synapse
    2793 (GNGT2)
   04725 Cholinergic synapse
    2793 (GNGT2)
   04728 Dopaminergic synapse
    2793 (GNGT2)
   04726 Serotonergic synapse
    2793 (GNGT2)
   04723 Retrograde endocannabinoid signaling
    2793 (GNGT2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2793 (GNGT2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2793 (GNGT2)
  09165 Substance dependence
   05032 Morphine addiction
    2793 (GNGT2)
   05034 Alcoholism
    2793 (GNGT2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    2793 (GNGT2)
   05163 Human cytomegalovirus infection
    2793 (GNGT2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2793 (GNGT2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:hsa04031]
    2793 (GNGT2)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    2793 (GNGT2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma Myc-LZ
Motif
Other DBs
NCBI-GeneID: 2793
NCBI-ProteinID: NP_001185683
OMIM: 139391
HGNC: 4412
Ensembl: ENSG00000167083
Vega: OTTHUMG00000161308
Pharos: O14610(Tdark)
UniProt: O14610
LinkDB All DBs
Position
17q21.32
AA seq 69 aa AA seqDB search
MAQDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPF
KEKGGCLIS
NT seq 210 nt NT seq  +upstreamnt  +downstreamnt
atggcccaggatctcagcgagaaggacctgttgaagatggaggtggagcagctgaagaaa
gaagtgaaaaacacaagaattccgatttccaaagcgggaaaggaaatcaaggagtacgtg
gaggcccaagcaggaaacgatccttttctcaaaggcatccctgaggacaagaatcccttc
aaggagaaaggtggctgtctgataagctga

KEGG   Homo sapiens (human): 51764Help
Entry
51764             CDS       T01001                                 

Gene name
GNG13, G(gamma)13, h2-35
Definition
(RefSeq) G protein subunit gamma 13
  KO
K04547  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04740  Olfactory transduction
hsa04742  Taste transduction
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    51764 (GNG13)
   04371 Apelin signaling pathway
    51764 (GNG13)
   04151 PI3K-Akt signaling pathway
    51764 (GNG13)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    51764 (GNG13)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    51764 (GNG13)
  09156 Nervous system
   04724 Glutamatergic synapse
    51764 (GNG13)
   04727 GABAergic synapse
    51764 (GNG13)
   04725 Cholinergic synapse
    51764 (GNG13)
   04728 Dopaminergic synapse
    51764 (GNG13)
   04726 Serotonergic synapse
    51764 (GNG13)
   04723 Retrograde endocannabinoid signaling
    51764 (GNG13)
  09157 Sensory system
   04740 Olfactory transduction
    51764 (GNG13)
   04742 Taste transduction
    51764 (GNG13)
  09159 Environmental adaptation
   04713 Circadian entrainment
    51764 (GNG13)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    51764 (GNG13)
  09165 Substance dependence
   05032 Morphine addiction
    51764 (GNG13)
   05034 Alcoholism
    51764 (GNG13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    51764 (GNG13)
   05163 Human cytomegalovirus infection
    51764 (GNG13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    51764 (GNG13)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:hsa04031]
    51764 (GNG13)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    51764 (GNG13)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma
Motif
Other DBs
NCBI-GeneID: 51764
NCBI-ProteinID: NP_057625
OMIM: 607298
HGNC: 14131
Ensembl: ENSG00000127588
Vega: OTTHUMG00000047839
Pharos: Q9P2W3(Tbio)
UniProt: Q9P2W3
LinkDB All DBs
Position
16p13.3
AA seq 67 aa AA seqDB search
MEEWDVPQMKKEVESLKYQLAFQREMASKTIPELLKWIEDGIPKDPFLNPDLMKNNPWVE
KGKCTIL
NT seq 204 nt NT seq  +upstreamnt  +downstreamnt
atggaggagtgggacgtgccacagatgaagaaagaggtggagagcctcaagtaccagctg
gccttccagcgggagatggcgtccaagaccatccccgagctgctgaagtggatcgaggac
gggatccccaaggaccccttcctgaaccccgacctgatgaagaacaacccatgggtggaa
aagggcaaatgcaccatcctgtga

KEGG   Homo sapiens (human): 54331Help
Entry
54331             CDS       T01001                                 

Gene name
GNG2
Definition
(RefSeq) G protein subunit gamma 2
  KO
K07826  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    54331 (GNG2)
   04371 Apelin signaling pathway
    54331 (GNG2)
   04151 PI3K-Akt signaling pathway
    54331 (GNG2)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    54331 (GNG2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    54331 (GNG2)
  09156 Nervous system
   04724 Glutamatergic synapse
    54331 (GNG2)
   04727 GABAergic synapse
    54331 (GNG2)
   04725 Cholinergic synapse
    54331 (GNG2)
   04728 Dopaminergic synapse
    54331 (GNG2)
   04726 Serotonergic synapse
    54331 (GNG2)
   04723 Retrograde endocannabinoid signaling
    54331 (GNG2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    54331 (GNG2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    54331 (GNG2)
  09165 Substance dependence
   05032 Morphine addiction
    54331 (GNG2)
   05034 Alcoholism
    54331 (GNG2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    54331 (GNG2)
   05163 Human cytomegalovirus infection
    54331 (GNG2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    54331 (GNG2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    54331 (GNG2)
   04031 GTP-binding proteins [BR:hsa04031]
    54331 (GNG2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   54331 (GNG2)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    54331 (GNG2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma FtsX_ECD CP12 CHASE8
Motif
Other DBs
NCBI-GeneID: 54331
NCBI-ProteinID: NP_001230702
OMIM: 606981
HGNC: 4404
Ensembl: ENSG00000186469
Vega: OTTHUMG00000171083
Pharos: P59768(Tbio)
UniProt: P59768
LinkDB All DBs
Structure
PDB: 

Position
14q22.1
AA seq 71 aa AA seqDB search
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENP
FREKKFFCAIL
NT seq 216 nt NT seq  +upstreamnt  +downstreamnt
atggccagcaacaacaccgccagcatagcacaagccaggaagctggtagagcagcttaag
atggaagccaatatcgacaggataaaggtgtccaaggcagctgcagatttgatggcctac
tgtgaagcacatgccaaggaagaccccctcctgacccctgttccggcttcagaaaacccg
tttagggagaagaagtttttctgtgccatcctttaa

KEGG   Homo sapiens (human): 55970Help
Entry
55970             CDS       T01001                                 

Gene name
GNG12
Definition
(RefSeq) G protein subunit gamma 12
  KO
K04347  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04810  Regulation of actin cytoskeleton
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    55970 (GNG12)
   04010 MAPK signaling pathway
    55970 (GNG12)
   04371 Apelin signaling pathway
    55970 (GNG12)
   04151 PI3K-Akt signaling pathway
    55970 (GNG12)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    55970 (GNG12)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    55970 (GNG12)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    55970 (GNG12)
  09156 Nervous system
   04724 Glutamatergic synapse
    55970 (GNG12)
   04727 GABAergic synapse
    55970 (GNG12)
   04725 Cholinergic synapse
    55970 (GNG12)
   04728 Dopaminergic synapse
    55970 (GNG12)
   04726 Serotonergic synapse
    55970 (GNG12)
   04723 Retrograde endocannabinoid signaling
    55970 (GNG12)
  09159 Environmental adaptation
   04713 Circadian entrainment
    55970 (GNG12)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    55970 (GNG12)
  09165 Substance dependence
   05032 Morphine addiction
    55970 (GNG12)
   05034 Alcoholism
    55970 (GNG12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    55970 (GNG12)
   05163 Human cytomegalovirus infection
    55970 (GNG12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    55970 (GNG12)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    55970 (GNG12)
   04031 GTP-binding proteins [BR:hsa04031]
    55970 (GNG12)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   55970 (GNG12)
  Exosomal proteins of colorectal cancer cells
   55970 (GNG12)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    55970 (GNG12)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma CP12
Motif
Other DBs
NCBI-GeneID: 55970
NCBI-ProteinID: NP_061329
OMIM: 615405
HGNC: 19663
Ensembl: ENSG00000172380
Vega: OTTHUMG00000009545
Pharos: Q9UBI6(Tbio)
UniProt: Q9UBI6
LinkDB All DBs
Position
1p31.3
AA seq 72 aa AA seqDB search
MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSE
NPFKDKKTCIIL
NT seq 219 nt NT seq  +upstreamnt  +downstreamnt
atgtccagcaaaacagcaagcaccaacaatatagcccaggcaaggagaactgtgcagcag
ttaagattagaagcctccattgaaagaataaaggtttcgaaggcatcagcggacctcatg
tcctactgtgaggaacatgccaggagtgaccctttgctgataggaataccaacttcagaa
aaccctttcaaggataaaaaaacttgcatcatcttatag

KEGG   Homo sapiens (human): 59345Help
Entry
59345             CDS       T01001                                 

Gene name
GNB4, CMTD1F
Definition
(RefSeq) G protein subunit beta 4
  KO
K04538  guanine nucleotide-binding protein subunit beta-4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Disease
H00264  Charcot-Marie-Tooth disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    59345 (GNB4)
   04371 Apelin signaling pathway
    59345 (GNB4)
   04151 PI3K-Akt signaling pathway
    59345 (GNB4)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    59345 (GNB4)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    59345 (GNB4)
  09156 Nervous system
   04724 Glutamatergic synapse
    59345 (GNB4)
   04727 GABAergic synapse
    59345 (GNB4)
   04725 Cholinergic synapse
    59345 (GNB4)
   04728 Dopaminergic synapse
    59345 (GNB4)
   04726 Serotonergic synapse
    59345 (GNB4)
   04723 Retrograde endocannabinoid signaling
    59345 (GNB4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    59345 (GNB4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    59345 (GNB4)
  09165 Substance dependence
   05032 Morphine addiction
    59345 (GNB4)
   05034 Alcoholism
    59345 (GNB4)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    59345 (GNB4)
   05163 Human cytomegalovirus infection
    59345 (GNB4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    59345 (GNB4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    59345 (GNB4)
   04031 GTP-binding proteins [BR:hsa04031]
    59345 (GNB4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   59345 (GNB4)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Beta Subunits
   Beta [OT]
    59345 (GNB4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: WD40 ANAPC4_WD40 WD40_like eIF2A
Motif
Other DBs
NCBI-GeneID: 59345
NCBI-ProteinID: NP_067642
OMIM: 610863
HGNC: 20731
Ensembl: ENSG00000114450
Vega: OTTHUMG00000157440
Pharos: Q9HAV0(Tbio)
UniProt: Q9HAV0
LinkDB All DBs
Position
3q26.33
AA seq 340 aa AA seqDB search
MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGRIQMRTRRTLRGHLAKIYA
MHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNI
CSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTF
TGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYA
FATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL
KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN
NT seq 1023 nt NT seq  +upstreamnt  +downstreamnt
atgagcgaactggaacagttgaggcaagaagcagaacaactgcggaatcagattcaggat
gctcggaaagcatgtaatgatgcaacgcttgttcagattacatcaaatatggactctgtg
ggtcgaatacaaatgcgaacaagacgtacactgaggggccacctagctaaaatctatgct
atgcattggggatacgattccaggctgctagtcagtgcttctcaagatggaaaattaatt
atttgggatagctatacaacaaataagatgcatgctattcctttgaggtcctcctgggtg
atgacctgtgcttatgctccctctggtaattatgttgcctgtggaggcttggacaacatc
tgctctatatataacttaaagaccagagagggaaatgtgagagtaagccgagagttgcca
ggtcacacagggtacttgtcctgctgtcgttttttagatgacagccaaattgttacaagt
tcaggagatacaacttgtgctttatgggacatcgaaactgcccagcagaccaccacattc
actgggcattctggagatgtgatgagtctttctttgagtcctgacatgaggacttttgtt
tctggtgcttgtgatgcctcttccaaattatgggatattcgagatggaatgtgtagacag
tctttcacgggacatgtctcagatatcaatgctgtcagttttttcccaaatggatatgcc
ttcgccactggctctgatgatgccacttgccggctctttgaccttcgtgcagatcaagag
ttattattgtattctcatgacaatatcatctgtggaatcacttctgtagccttctcaaaa
agtgggcgtctcttgttggctggttacgatgactttaattgtaatgtatgggacacgcta
aaaggagatcgtgcaggtgtccttgctggtcatgacaaccgtgtgagctgcttaggtgta
actgatgatggcatggctgtggcaacaggctcttgggacagttttcttagaatctggaat
taa

KEGG   Homo sapiens (human): 94235Help
Entry
94235             CDS       T01001                                 

Gene name
GNG8
Definition
(RefSeq) G protein subunit gamma 8
  KO
K04544  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06124  Chemokine signaling (virus)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    94235 (GNG8)
   04371 Apelin signaling pathway
    94235 (GNG8)
   04151 PI3K-Akt signaling pathway
    94235 (GNG8)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    94235 (GNG8)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    94235 (GNG8)
  09156 Nervous system
   04724 Glutamatergic synapse
    94235 (GNG8)
   04727 GABAergic synapse
    94235 (GNG8)
   04725 Cholinergic synapse
    94235 (GNG8)
   04728 Dopaminergic synapse
    94235 (GNG8)
   04726 Serotonergic synapse
    94235 (GNG8)
   04723 Retrograde endocannabinoid signaling
    94235 (GNG8)
  09159 Environmental adaptation
   04713 Circadian entrainment
    94235 (GNG8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    94235 (GNG8)
  09165 Substance dependence
   05032 Morphine addiction
    94235 (GNG8)
   05034 Alcoholism
    94235 (GNG8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    94235 (GNG8)
   05163 Human cytomegalovirus infection
    94235 (GNG8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    94235 (GNG8)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:hsa04031]
    94235 (GNG8)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    94235 (GNG8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma Flexi_CP
Motif
Other DBs
NCBI-GeneID: 94235
NCBI-ProteinID: NP_150283
HGNC: 19664
Ensembl: ENSG00000167414
Vega: OTTHUMG00000183430
Pharos: Q9UK08(Tdark)
UniProt: Q9UK08
LinkDB All DBs
Position
19q13.32
AA seq 70 aa AA seqDB search
MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPF
RDKRLFCVLL
NT seq 213 nt NT seq  +upstreamnt  +downstreamnt
atgtccaacaacatggccaagattgccgaggcccgcaagacggtggaacagctgaagctg
gaggtgaacatcgaccgcatgaaggtgtcgcaggcagcagcggaactcctggctttctgc
gagacgcatgccaaagatgacccgctggtgacgccagtacccgccgcggagaaccccttc
cgcgacaagcgcctcttttgtgttctgctctga

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