Entry |
|
Gene name |
CFL1, CFL, HEL-S-15, cofilin
|
Definition |
|
KO |
|
Organism |
|
Pathway |
hsa04666 | Fc gamma R-mediated phagocytosis |
hsa04810 | Regulation of actin cytoskeleton |
hsa05170 | Human immunodeficiency virus 1 infection |
|
Network |
nt06124 Chemokine signaling (viruses) nt06150 Cytokine-cytokine receptor interaction (viruses) nt06161 Human immunodeficiency virus type 1 (HIV-1) |
Element |
N00433 | CXCR4-GNB/G-RAC signaling pathway |
N00434 | HIV gp120 to CXCR4-GNB/G-RAC signaling pathway |
|
Brite |
KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
1072 (CFL1)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
1072 (CFL1)
09158 Development and regeneration
04360 Axon guidance
1072 (CFL1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
1072 (CFL1)
09171 Infectious disease: bacterial
05133 Pertussis
1072 (CFL1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:hsa04131]
1072 (CFL1)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:hsa04812]
1072 (CFL1)
04147 Exosome [BR:hsa04147]
1072 (CFL1)
Membrane trafficking [BR:hsa04131]
Others
Actin-binding proteins
Others
1072 (CFL1)
Cytoskeleton proteins [BR:hsa04812]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
ADF / Cofilin
1072 (CFL1)
Exosome [BR:hsa04147]
Exosomal proteins
Proteins found in most exosomes
1072 (CFL1)
|
SSDB |
|
Motif |
|
Other DBs |
|
LinkDB |
|
Structure |
PDB: |
Position |
11q13.1
|
AA seq |
166 aa
MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDV
GQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASS
KDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL |
NT seq |
501 nt +upstreamnt +downstreamnt
atggcctccggtgtggctgtctctgatggtgtcatcaaggtgttcaacgacatgaaggtg
cgtaagtcttcaacgccagaggaggtgaagaagcgcaagaaggcggtgctcttctgcctg
agtgaggacaagaagaacatcatcctggaggagggcaaggagatcctggtgggcgatgtg
ggccagactgtcgacgacccctacgccacctttgtcaagatgctgccagataaggactgc
cgctatgccctctatgatgcaacctatgagaccaaggagagcaagaaggaggatctggtg
tttatcttctgggcccccgagtctgcgccccttaagagcaaaatgatttatgccagctcc
aaggacgccatcaagaagaagctgacagggatcaagcatgaattgcaagcaaactgctac
gaggaggtcaaggaccgctgcaccctggcagagaagctggggggcagtgccgtcatctcc
ctggagggcaagcctttgtga |