Homo sapiens (human): 1072
Entry
1072 CDS
T01001
Gene name
CFL1, CFL, HEL-S-15, cofilin
Definition
(RefSeq) cofilin 1
KO
K05765
cofilin
Organism
hsa
Homo sapiens (human)
Pathway
hsa04360
Axon guidance
hsa04666
Fc gamma R-mediated phagocytosis
hsa04810
Regulation of actin cytoskeleton
hsa05133
Pertussis
hsa05170
Human immunodeficiency virus 1 infection
Network
nt06124
Chemokine signaling (viruses)
nt06161
Human immunodeficiency virus type 1 (HIV-1)
Element
N00433
CXCR4-GNB/G-RAC signaling pathway
N00434
HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
1072 (CFL1)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
1072 (CFL1)
09158 Development and regeneration
04360 Axon guidance
1072 (CFL1)
09160 Human Diseases
09171 Infectious disease: bacterial
05133 Pertussis
1072 (CFL1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
1072 (CFL1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
1072 (CFL1)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
1072 (CFL1)
04147 Exosome [BR:
hsa04147
]
1072 (CFL1)
Membrane trafficking [BR:
hsa04131
]
Others
Actin-binding proteins
Others
1072 (CFL1)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
ADF / Cofilin
1072 (CFL1)
Exosome [BR:
hsa04147
]
Exosomal proteins
Proteins found in most exosomes
1072 (CFL1)
SSDB
Motif
Pfam:
Cofilin_ADF
Other DBs
NCBI-GeneID:
1072
NCBI-ProteinID:
NP_005498
OMIM:
601442
HGNC:
1874
Ensembl:
ENSG00000172757
Vega:
OTTHUMG00000166602
Pharos:
P23528
(Tbio)
UniProt:
P23528
V9HWI5
LinkDB
Structure
PDB:
5L6W
4BEX
5HVK
3J0S
1Q8X
1Q8G
Position
11q13.1
AA seq
166 aa
MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDV
GQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASS
KDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL
NT seq
501 nt
+upstream
nt +downstream
nt
atggcctccggtgtggctgtctctgatggtgtcatcaaggtgttcaacgacatgaaggtg
cgtaagtcttcaacgccagaggaggtgaagaagcgcaagaaggcggtgctcttctgcctg
agtgaggacaagaagaacatcatcctggaggagggcaaggagatcctggtgggcgatgtg
ggccagactgtcgacgacccctacgccacctttgtcaagatgctgccagataaggactgc
cgctatgccctctatgatgcaacctatgagaccaaggagagcaagaaggaggatctggtg
tttatcttctgggcccccgagtctgcgccccttaagagcaaaatgatttatgccagctcc
aaggacgccatcaagaagaagctgacagggatcaagcatgaattgcaagcaaactgctac
gaggaggtcaaggaccgctgcaccctggcagagaagctggggggcagtgccgtcatctcc
ctggagggcaagcctttgtga
Homo sapiens (human): 1073
Entry
1073 CDS
T01001
Gene name
CFL2, NEM7
Definition
(RefSeq) cofilin 2
KO
K05765
cofilin
Organism
hsa
Homo sapiens (human)
Pathway
hsa04360
Axon guidance
hsa04666
Fc gamma R-mediated phagocytosis
hsa04810
Regulation of actin cytoskeleton
hsa05133
Pertussis
hsa05170
Human immunodeficiency virus 1 infection
Network
nt06124
Chemokine signaling (viruses)
nt06161
Human immunodeficiency virus type 1 (HIV-1)
Element
N00433
CXCR4-GNB/G-RAC signaling pathway
N00434
HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
Disease
H00698
Nemaline myopathy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
1073 (CFL2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
1073 (CFL2)
09158 Development and regeneration
04360 Axon guidance
1073 (CFL2)
09160 Human Diseases
09171 Infectious disease: bacterial
05133 Pertussis
1073 (CFL2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
1073 (CFL2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
1073 (CFL2)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
1073 (CFL2)
04147 Exosome [BR:
hsa04147
]
1073 (CFL2)
Membrane trafficking [BR:
hsa04131
]
Others
Actin-binding proteins
Others
1073 (CFL2)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
ADF / Cofilin
1073 (CFL2)
Exosome [BR:
hsa04147
]
Exosomal proteins
Proteins found in most exosomes
1073 (CFL2)
SSDB
Motif
Pfam:
Cofilin_ADF
Other DBs
NCBI-GeneID:
1073
NCBI-ProteinID:
NP_068733
OMIM:
601443
HGNC:
1875
Ensembl:
ENSG00000165410
Vega:
OTTHUMG00000029536
Pharos:
Q9Y281
(Tbio)
UniProt:
Q9Y281
Q549N0
LinkDB
Position
14q13.1
AA seq
166 aa
MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDI
GDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASS
KDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL
NT seq
501 nt
+upstream
nt +downstream
nt
atggcttctggagttacagtgaatgatgaagtcatcaaagtttttaatgatatgaaagta
aggaaatcttctacacaagaggagatcaaaaagagaaagaaagcagttctcttctgttta
agcgatgacaaaagacaaataattgtagaggaagcaaagcagatcttggtgggtgacatt
ggtgatactgtagaggacccctacacatcttttgtgaagttgctacctctgaatgattgc
cgatatgctttgtacgatgccacatacgaaacaaaagagtctaagaaagaagacctagta
tttatattctgggctcctgaaagtgcacctttaaaaagcaagatgatttatgctagctct
aaagatgccattaaaaagaaatttacaggtattaaacatgagtggcaagtaaatggcttg
gatgatattaaggaccgttcgacacttggagagaaattgggaggcaatgtagtagtttca
cttgaaggaaaaccattataa
DBGET
integrated database retrieval system
