KEGG   Homo sapiens (human): 1128Help
Entry
1128              CDS       T01001                                 

Gene name
CHRM1, HM1, M1, M1R
Definition
(RefSeq) cholinergic receptor muscarinic 1
  KO
K04129  muscarinic acetylcholine receptor M1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04151  PI3K-Akt signaling pathway
hsa04725  Cholinergic synapse
hsa04810  Regulation of actin cytoskeleton
Drug target
Aceclidine: D02750
Acetylcholine (DG01133): D00999
Aclatonium (DG01291): D01955
Aclidinium bromide: D08837
Alvameline maleate: D02876
Anisotropine methylbromide: D00232
Atropine (DG00052): D00113 D02069
Atropine oxide (DG01243): D03011 D07477
Batefenterol (DG01627): D10545 D10546
Benapryzine hydrochloride: D03076
Benzatropine (DG00859): D00778 D07511
Benzetimide (DG01301): D03087 D07513
Benzilone: D03088
Bethanechol (DG00991): D01000
Bevonium: D01532
Biperiden (DG00852): D00779 D02246 D02247
Blarcamesine (DG03048): D11383 D11549
Bornaprine: D07302
Butropium bromide: D01491
Butylscopolamine: D01451
Carbachol: D00524
Carpronium (DG01289): D01175 D09752
Chlorpromazine (DG00867): D00270 D00789 D03274 D04034 D09819
Choline alfoscerate: D07349
Cimetropium bromide: D07099
Clidinium bromide: D00716
Cyclopentolate (DG01141): D01002 D07759
Darotropium bromide: D09402
Dexetimide (DG00856): D03711 D07804
Dicycloverine (DG00032): D00717 D07820
Diethazine (DG01921): D02603 D07823
Difemerine: D07079
Dihexyverine (DG00033): D03824 D07821
Diphenidol (DG02880): D01318 D03858 D03859
Diphenylpiperidinomethyldioxolan iodide: D01600
Diponium bromide: D01463
Elantrine: D03970
Elucaine: D03979
Esoxybutynin chloride: D04057
Etomidoline: D01359
Etybenzatropine: D04087
Eucatropine hydrochloride: D04116
Fenpiverinium: D07070
Fentonium: D07951
Flutropium bromide: D02417
Glycopyrronium (DG02467): D10939
Heteronium bromide: D04434
Homatropine (DG01142): D01004 D02070
Hyoscyamine (DG00053): D00147 D00719 D01648 D04479
Imidafenacin: D06273
Ipratropium bromide: D02212
Mazaticol (DG00857): D03264 D08157
Mebeverine (DG00030): D04868 D08160
Mepenzolate (DG00040): D00720
Methacholine (DG01290): D04970
Methantheline (DG00036): D00721
Methscopolamine bromide: D00715
Methylatropine (DG01242): D01077 D03814
Methylbenactyzium bromide: D01315
Methylscopolamine: D01976
Metixene (DG00853): D01871 D08209
Metoquizine: D05012
Milameline hydrochloride: D05035
Otilonium bromide: D07083
Oxapium iodide: D01815
Oxitropium bromide: D01946
Oxybutynin (DG00478): D00465 D00722
Oxyphencyclimine (DG00029): D01006 D08325
Oxyphenonium: D06877
Parapenzolate bromide: D05360
Pentapiperium methylsulfate: D05418
Penthienate: D07081
Phencarbamide: D05452
Phenglutarimide: D07301
Pipenzolate: D07084
Piperidolate (DG00034): D01165 D08382
Pipethanate (DG01255): D01521 D08384
Pipethanate ethobromide: D01987
Pirenzepine (DG00026): D01297 D05276 D08389
Piroheptine (DG01272): D01231 D08395
Poldine: D05535
Pridinol (DG00774): D02064 D08418 D08419
Prifinium bromide: D01377
Procyclidine (DG00854): D00782 D08425
Profenamine (DG00855): D01118 D03276 D08426
Propantheline (DG00035): D00481
Propenzolate hydrochloride: D05628
Propiverine (DG00479): D01007 D08441
Rapacuronium bromide: D05703
Revefenacin: D10978
Rocuronium bromide: D00765
Sabcomeline hydrochloride: D05779
Scopolamine (DG00065): D00138 D02071
Sofpironium bromide: D10989
Talsaclidine fumarate: D06000
Tazomeline citrate: D06015
Telenzepine hydrochloride hydrate: D11098
Tematropium methylsulfate: D06061
Tiemonium (DG01254): D08595
Tiemonium iodide: D01201
Timepidium bromide (DG00041): D02535
Tofenacin hydrochloride: D06175
Toquizine: D06192
Triampyzine sulfate: D06217
Tridihexethyl (DG00037): D00723
Trihexyphenidyl (DG00851): D00787 D08638
Tropatepine (DG00858): D07303 D08653
Tropicamide: D00397
Umeclidinium (DG01253): D10180
Umeclidinium bromide: D10181
Valethamate: D01538
Xanomeline (DG01300): D06330 D06331
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    1128 (CHRM1)
   04024 cAMP signaling pathway
    1128 (CHRM1)
   04151 PI3K-Akt signaling pathway
    1128 (CHRM1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    1128 (CHRM1)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    1128 (CHRM1)
 09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    1128 (CHRM1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    1128 (CHRM1)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Acetylcholine (muscarinic)
    1128 (CHRM1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx 7TM_GPCR_Srbc
Motif
Other DBs
NCBI-GeneID: 1128
NCBI-ProteinID: NP_000729
OMIM: 118510
HGNC: 1950
Ensembl: ENSG00000168539
Vega: OTTHUMG00000167765
Pharos: P11229(Tclin)
UniProt: P11229 Q53XZ3
LinkDB All DBs
Structure
PDB: 

Position
11q12.3
AA seq 460 aa AA seqDB search
MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
NT seq 1383 nt NT seq  +upstreamnt  +downstreamnt
atgaacacttcagccccacctgctgtcagccccaacatcaccgtcctggcaccaggaaag
ggtccctggcaagtggccttcattgggatcaccacgggcctcctgtcgctagccacagtg
acaggcaacctgctggtactcatctctttcaaggtcaacacggagctcaagacagtcaat
aactacttcctgctgagcctggcctgtgctgacctcatcatcggtaccttctccatgaac
ctctataccacgtacctgctcatgggccactgggctctgggcacgctggcttgtgacctc
tggctggccctggactatgtggccagcaatgcctccgtcatgaatctgctgctcatcagc
tttgaccgctacttctccgtgactcggcccctgagctaccgtgccaagcgcacaccccgc
cgggcagctctgatgatcggcctggcctggctggtttcctttgtgctctgggccccagcc
atcctcttctggcagtacctggtaggggagcggacagtgctagctgggcagtgctacatc
cagttcctctcccagcccatcatcacctttggcacagccatggctgccttctacctccct
gtcacagtcatgtgcacgctctactggcgcatctaccgggagacagagaaccgagcacgg
gagctggcagcccttcagggctccgagacgccaggcaaagggggtggcagcagcagcagc
tcagagaggtctcagccaggggctgagggctcaccagagactcctccaggccgctgctgt
cgctgctgccgggcccccaggctgctgcaggcctacagctggaaggaagaagaggaagag
gacgaaggctccatggagtccctcacatcctcagagggagaggagcctggctccgaagtg
gtgatcaagatgccaatggtggaccccgaggcacaggcccccaccaagcagcccccacgg
agctccccaaatacagtcaagaggccgactaagaaagggcgtgatcgagctggcaagggc
cagaagccccgtggaaaggagcagctggccaagcggaagaccttctcgctggtcaaggag
aagaaggcggctcggaccctgagtgccatcctcctggccttcatcctcacctggacaccg
tacaacatcatggtgctggtgtccaccttctgcaaggactgtgttcccgagaccctgtgg
gagctgggctactggctgtgctacgtcaacagcaccatcaaccccatgtgctacgcactc
tgcaacaaagccttccgggacacctttcgcctgctgctgctttgccgctgggacaagaga
cgctggcgcaagatccccaagcgccctggctccgtgcaccgcactccctcccgccaatgc
tga

KEGG   Homo sapiens (human): 1129Help
Entry
1129              CDS       T01001                                 

Gene name
CHRM2, HM2
Definition
(RefSeq) cholinergic receptor muscarinic 2
  KO
K04130  muscarinic acetylcholine receptor M2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04151  PI3K-Akt signaling pathway
hsa04725  Cholinergic synapse
hsa04810  Regulation of actin cytoskeleton
Drug target
Acetylcholine (DG01133): D00999
Aclatonium (DG01291): D01955
Aclidinium bromide: D08837
Alvameline maleate: D02876
Anisotropine methylbromide: D00232
Atropine (DG00052): D00113 D02069
Atropine oxide (DG01243): D03011 D07477
Batefenterol (DG01627): D10545 D10546
Benapryzine hydrochloride: D03076
Benzatropine (DG00859): D00778 D07511
Benzetimide (DG01301): D03087 D07513
Benzilone: D03088
Bethanechol (DG00991): D01000
Bevonium: D01532
Biperiden (DG00852): D00779 D02246 D02247
Blarcamesine (DG03048): D11383 D11549
Bornaprine: D07302
Butropium bromide: D01491
Butylscopolamine: D01451
Carbachol: D00524
Carpronium (DG01289): D01175 D09752
Chlorpromazine (DG00867): D00270 D00789 D03274 D04034 D09819
Choline alfoscerate: D07349
Cimetropium bromide: D07099
Clidinium bromide: D00716
Cyclopentolate (DG01141): D01002 D07759
Darotropium bromide: D09402
Dexetimide (DG00856): D03711 D07804
Dicycloverine (DG00032): D00717 D07820
Diethazine (DG01921): D02603 D07823
Difemerine: D07079
Dihexyverine (DG00033): D03824 D07821
Dimetindene (DG00386): D07853
Diphenidol (DG02880): D01318 D03858 D03859
Diphenylpiperidinomethyldioxolan iodide: D01600
Diponium bromide: D01463
Elantrine: D03970
Elucaine: D03979
Esoxybutynin chloride: D04057
Etomidoline: D01359
Etybenzatropine: D04087
Eucatropine hydrochloride: D04116
Fenpiverinium: D07070
Fentonium: D07951
Fesoterodine (DG00483): D07226 D08923
Flutropium bromide: D02417
Gallamine: D02292
Glycopyrronium (DG02467): D10939
Heteronium bromide: D04434
Homatropine (DG01142): D01004 D02070
Hyoscyamine (DG00053): D00147 D00719 D01648 D04479
Ipratropium bromide: D02212
Mazaticol (DG00857): D03264 D08157
Mebeverine (DG00030): D04868 D08160
Mepenzolate (DG00040): D00720
Methacholine (DG01290): D04970
Methantheline (DG00036): D00721
Methscopolamine bromide: D00715
Methylatropine (DG01242): D01077 D03814
Methylbenactyzium bromide: D01315
Methylscopolamine: D01976
Metixene (DG00853): D01871 D08209
Metoquizine: D05012
Milameline hydrochloride: D05035
Otilonium bromide: D07083
Oxapium iodide: D01815
Oxitropium bromide: D01946
Oxybutynin (DG00478): D00465 D00722
Oxyphencyclimine (DG00029): D01006 D08325
Parapenzolate bromide: D05360
Pentapiperium methylsulfate: D05418
Penthienate: D07081
Phencarbamide: D05452
Phenglutarimide: D07301
Pilocarpine (DG00992): D00525 D02200 D05478 D08376
Pipenzolate: D07084
Piperidolate (DG00034): D01165 D08382
Pipethanate (DG01255): D01521 D08384
Pipethanate ethobromide: D01987
Pirenzepine (DG00026): D01297 D05276 D08389
Piroheptine (DG01272): D01231 D08395
Poldine: D05535
Pridinol (DG00774): D02064 D08418 D08419
Prifinium bromide: D01377
Procyclidine (DG00854): D00782 D08425
Profenamine (DG00855): D01118 D03276 D08426
Propantheline (DG00035): D00481
Propenzolate hydrochloride: D05628
Propiverine (DG00479): D01007 D08441
Rapacuronium bromide: D05703
Revefenacin: D10978
Rocuronium bromide: D00765
Scopolamine (DG00065): D00138 D02071
Sofpironium bromide: D10989
Tazomeline citrate: D06015
Tematropium methylsulfate: D06061
Tiemonium (DG01254): D08595
Tiemonium iodide: D01201
Timepidium bromide (DG00041): D02535
Tofenacin hydrochloride: D06175
Toquizine: D06192
Triampyzine sulfate: D06217
Tridihexethyl (DG00037): D00723
Trihexyphenidyl (DG00851): D00787 D08638
Tropatepine (DG00858): D07303 D08653
Tropicamide: D00397
Trospium: D01103
Umeclidinium (DG01253): D10180
Umeclidinium bromide: D10181
Valethamate: D01538
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    1129 (CHRM2)
   04024 cAMP signaling pathway
    1129 (CHRM2)
   04151 PI3K-Akt signaling pathway
    1129 (CHRM2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    1129 (CHRM2)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    1129 (CHRM2)
 09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    1129 (CHRM2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    1129 (CHRM2)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Acetylcholine (muscarinic)
    1129 (CHRM2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srx 7tm_4
Motif
Other DBs
NCBI-GeneID: 1129
NCBI-ProteinID: NP_000730
OMIM: 118493
HGNC: 1951
Ensembl: ENSG00000181072
Vega: OTTHUMG00000155658
Pharos: P08172(Tclin)
UniProt: P08172 A4D1Q0 Q6SL56 Q86SJ1
LinkDB All DBs
Structure
PDB: 

Position
7q33
AA seq 466 aa AA seqDB search
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
NT seq 1401 nt NT seq  +upstreamnt  +downstreamnt
atgaataactcaacaaactcctctaacaatagcctggctcttacaagtccttataagaca
tttgaagtggtgtttattgtcctggtggctggatccctcagtttggtgaccattatcggg
aacatcctagtcatggtttccattaaagtcaaccgccacctccagaccgtcaacaattac
tttttattcagcttggcctgtgctgaccttatcataggtgttttctccatgaacttgtac
accctctacactgtgattggttactggcctttgggacctgtggtgtgtgacctttggcta
gccctggactatgtggtcagcaatgcctcagttatgaatctgctcatcatcagctttgac
aggtacttctgtgtcacaaaacctctgacctacccagtcaagcggaccacaaaaatggca
ggtatgatgattgcagctgcctgggtcctctctttcatcctctgggctccagccattctc
ttctggcagttcattgtaggggtgagaactgtggaggatggggagtgctacattcagttt
ttttccaatgctgctgtcacctttggtacggctattgcagccttctatttgccagtgatc
atcatgactgtgctatattggcacatatcccgagccagcaagagcaggataaagaaggac
aagaaggagcctgttgccaaccaagaccccgtttctccaagtctggtacaaggaaggata
gtgaagccaaacaataacaacatgcccagcagtgacgatggcctggagcacaacaaaatc
cagaatggcaaagcccccagggatcctgtgactgaaaactgtgttcagggagaggagaag
gagagctccaatgactccacctcagtcagtgctgttgcctctaatatgagagatgatgaa
ataacccaggatgaaaacacagtttccacttccctgggccattccaaagatgagaactct
aagcaaacatgcatcagaattggcaccaagaccccaaaaagtgactcatgtaccccaact
aataccaccgtggaggtagtggggtcttcaggtcagaatggagatgaaaagcagaatatt
gtagcccgcaagattgtgaagatgactaagcagcctgcaaaaaagaagcctcctccttcc
cgggaaaagaaagtcaccaggacaatcttggctattctgttggctttcatcatcacttgg
gccccatacaatgtcatggtgctcattaacaccttttgtgcaccttgcatccccaacact
gtgtggacaattggttactggctttgttacatcaacagcactatcaaccctgcctgctat
gcactttgcaatgccaccttcaagaagacctttaaacaccttctcatgtgtcattataag
aacataggcgctacaaggtaa

KEGG   Homo sapiens (human): 134Help
Entry
134               CDS       T01001                                 

Gene name
ADORA1, RDC7
Definition
(RefSeq) adenosine A1 receptor
  KO
K04265  adenosine receptor A1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04071  Sphingolipid signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04923  Regulation of lipolysis in adipocytes
hsa04924  Renin secretion
hsa05032  Morphine addiction
Drug target
Adenosine (DG00243): D00045 D02300 D02769 D08646 D08647
Aminophylline (DG01062): D00227 D05429 D11630
Apaxifylline: D02964
Bamifylline (DG01064): D03051 D07491
Caffeine (DG00974): D00528 D01453 D07603
Choline theophyllinate: D02017
Diprophylline: D00691
Enprofylline: D04006
Naxifylline: D05125
Proxyphylline: D01771
Rolofylline: D08989
Selodenoson: D05818
Tecadenoson: D06019
Theophylline (DG01061): D00371 D01712 D06103 D06104
Tonapofylline: D09684
Trabodenoson: D10493
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    134 (ADORA1)
   04024 cAMP signaling pathway
    134 (ADORA1)
   04022 cGMP-PKG signaling pathway
    134 (ADORA1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    134 (ADORA1)
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    134 (ADORA1)
   04924 Renin secretion
    134 (ADORA1)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    134 (ADORA1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    134 (ADORA1)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Base and nucleoside
   Adenosine
    134 (ADORA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx CcmH
Motif
Other DBs
NCBI-GeneID: 134
NCBI-ProteinID: NP_000665
OMIM: 102775
HGNC: 262
Ensembl: ENSG00000163485
Vega: OTTHUMG00000042125
Pharos: P30542(Tclin)
UniProt: P30542
LinkDB All DBs
Structure
PDB: 

Position
1q32.1
AA seq 326 aa AA seqDB search
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
NT seq 981 nt NT seq  +upstreamnt  +downstreamnt
atgccgccctccatctcagctttccaggccgcctacatcggcatcgaggtgctcatcgcc
ctggtctctgtgcccgggaacgtgctggtgatctgggcggtgaaggtgaaccaggcgctg
cgggatgccaccttctgcttcatcgtgtcgctggcggtggctgatgtggccgtgggtgcc
ctggtcatccccctcgccatcctcatcaacattgggccacagacctacttccacacctgc
ctcatggttgcctgtccggtcctcatcctcacccagagctccatcctggccctgctggca
attgctgtggaccgctacctccgggtcaagatccctctccggtacaagatggtggtgacc
ccccggagggcggcggtggccatagccggctgctggatcctctccttcgtggtgggactg
acccctatgtttggctggaacaatctgagtgcggtggagcgggcctgggcagccaacggc
agcatgggggagcccgtgatcaagtgcgagttcgagaaggtcatcagcatggagtacatg
gtctacttcaacttctttgtgtgggtgctgcccccgcttctcctcatggtcctcatctac
ctggaggtcttctacctaatccgcaagcagctcaacaagaaggtgtcggcctcctccggc
gacccgcagaagtactatgggaaggagctgaagatcgccaagtcgctggccctcatcctc
ttcctctttgccctcagctggctgcctttgcacatcctcaactgcatcaccctcttctgc
ccgtcctgccacaagcccagcatccttacctacattgccatcttcctcacgcacggcaac
tcggccatgaaccccattgtctatgccttccgcatccagaagttccgcgtcaccttcctt
aagatttggaatgaccatttccgctgccagcctgcacctcccattgacgaggatctccca
gaagagaggcctgatgactag

KEGG   Homo sapiens (human): 154Help
Entry
154               CDS       T01001                                 

Gene name
ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Definition
(RefSeq) adrenoceptor beta 2
  KO
K04142  adrenergic receptor beta-2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04923  Regulation of lipolysis in adipocytes
hsa04924  Renin secretion
hsa04970  Salivary secretion
Disease
H00079  Asthma
H02106  Genetic obesity
Drug target
Abediterol (DG01232): D10219 D10220
Adaprolol maleate: D02765
Alprenolol (DG00303): D01182 D07156
Alprenoxime hydrochloride: D02834
Amosulalol (DG01302): D01469 D07451
Arformoterol (DG01233): D02981 D07463
Arotinolol (DG01303): D01830 D07465
Bambuterol (DG01060): D07377 D07489
Batefenterol (DG01627): D10545 D10546
Bedoradrine sulfate: D06562
Befunolol (DG01138): D01512 D07496
Beradilol monoethyl maleate: D09843
Bitolterol (DG01056): D00684 D07534
Bopindolol (DG00310): D01794 D07537
Bucindolol hydrochloride: D03170
Bucumolol hydrochloride: D01492
Bufetolol hydrochloride: D01504
Bunitrolol hydrochloride: D01444
Bunolol hydrochloride: D03177
Bupranolol (DG00311): D01454 D07590
Butoxamine hydrochloride: D03198
Carazolol: D07608
Carbuterol: D03402
Carteolol (DG00308): D00599 D07624
Carvedilol (DG00321): D00255 D03415
Cimaterol: D03502
Clenbuterol (DG01053): D01360 D07713
Cloranolol: D07183
Clorprenaline hydrochloride: D01835
Colterol mesylate: D03587
Dexpropranolol hydrochloride: D03729
Diacetolol hydrochloride: D03759
Dilevalol hydrochloride: D01906
Dipivefrine (DG01129): D01017 D02349
Dopexamine (DG00222): D03891 D03892
Droxidopa: D01277
Ephedrine (DG00227): D00124 D01386 D04018
Epinephrine (DG00013): D00095 D00996 D02149
Epinephryl borate: D04026
Etafedrine hydrochloride: D04072
Etilefrine (DG00210): D01573 D07931
Exaprolol hydrochloride: D04120
Fenoterol (DG00451): D01428 D04157
Flestolol sulfate: D04190
Formoterol (DG01052): D01373 D05277 D07990
Hexoprenaline (DG01047): D02396 D08039
Indacaterol (DG01057): D09318 D09319 D11009
Indenolol (DG01323): D01958 D08078
Isoetarine (DG01234): D02093 D04625 D04626
Isoprenaline (DG00211): D01390 D02066 D02150 D08090
Isoxsuprine (DG00277): D01748 D08092 D08093
Labetalol (DG00320): D00600 D08106
Levalbuterol  
Levosalbutamol (DG01235): D02281 D04701 D04703 D08124
Levobunolol (DG01136): D01025 D08115
Mabuterol hydrochloride: D01589
Medroxalol (DG01317): D04888 D04889
Mepindolol: D07181
Metalol hydrochloride: D04953
Methoxyphenamine: D01635
Methylephedrine (DG01229): D01952 D02109 D08206 D09842
Metipranolol (DG01137): D02081 D02374
Milveterol hydrochloride: D08945
Nadolol: D00432
Nipradilol: D01691
Norepinephrine (DG00212): D00076 D05206 D08284 D09794
Octodrine: D05228
Olodaterol (DG01058): D10020 D10145
Orciprenaline (DG01044): D00685 D04954 D08300
Oxprenolol (DG00304): D01806 D08318
Pamatolol sulfate: D05345
Penbutolol (DG00312): D00602 D08074
Phenylpropanolamine (DG01041): D01224 D05466 D08368
Picumeterol fumarate: D05476
Pindolol: D00513
Pirbuterol (DG01048): D00686 D01349 D08387
Primidolol: D02389
Procaterol (DG01055): D02404 D05366 D08424
Propranolol (DG00305): D00483 D08443
Pseudoephedrine (DG01042): D00485 D05648 D05649 D08449
Racephedrine Hydrochloride: D08982
Racepinephrine (DG01444): D05688 D05689
Ractopamine hydrochloride: D05691
Reproterol (DG01054): D05718 D08474
Rimiterol: D05730
Ritodrine (DG00450): D01263 D02359
Salbutamol (DG01045): D00683 D02147
Salmeterol (DG01051): D00687 D05792
Sibenadet hydrochloride: D05832
Sotalol (DG00307): D01026 D08525
Soterenol hydrochloride: D05902
Talinolol: D07184
Tazolol hydrochloride: D06014
Terbutaline (DG01046): D00688 D08570
Tertatolol (DG00309): D07182 D08572
Tilisolol (DG01322): D01795 D08598
Timolol (DG00306): D00378 D00603 D08600
Tiprenolol hydrochloride: D06162
Tolamolol: D06176
Tretoquinol (DG01049): D01978 D05037 D08629
Tulobuterol (DG01050): D01362 D02151
Vilanterol (DG01236): D09696 D09697
Zinterol hydrochloride: D06374
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    154 (ADRB2)
   04024 cAMP signaling pathway
    154 (ADRB2)
   04022 cGMP-PKG signaling pathway
    154 (ADRB2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    154 (ADRB2)
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    154 (ADRB2)
   04924 Renin secretion
    154 (ADRB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    154 (ADRB2)
  09154 Digestive system
   04970 Salivary secretion
    154 (ADRB2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    154 (ADRB2)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Adrenaline
    154 (ADRB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7tm_4 7TM_GPCR_Srv
Motif
Other DBs
NCBI-GeneID: 154
NCBI-ProteinID: NP_000015
OMIM: 109690
HGNC: 286
Ensembl: ENSG00000169252
Vega: OTTHUMG00000129933
Pharos: P07550(Tclin)
UniProt: P07550
LinkDB All DBs
Structure
PDB: 

Position
5q32
AA seq 413 aa AA seqDB search
MGQPGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
NT seq 1242 nt NT seq  +upstreamnt  +downstreamnt
atggggcaacccgggaacggcagcgccttcttgctggcacccaatagaagccatgcgccg
gaccacgacgtcacgcagcaaagggacgaggtgtgggtggtgggcatgggcatcgtcatg
tctctcatcgtcctggccatcgtgtttggcaatgtgctggtcatcacagccattgccaag
ttcgagcgtctgcagacggtcaccaactacttcatcacttcactggcctgtgctgatctg
gtcatgggcctggcagtggtgccctttggggccgcccatattcttatgaaaatgtggact
tttggcaacttctggtgcgagttttggacttccattgatgtgctgtgcgtcacggccagc
attgagaccctgtgcgtgatcgcagtggatcgctactttgccattacttcacctttcaag
taccagagcctgctgaccaagaataaggcccgggtgatcattctgatggtgtggattgtg
tcaggccttacctccttcttgcccattcagatgcactggtaccgggccacccaccaggaa
gccatcaactgctatgccaatgagacctgctgtgacttcttcacgaaccaagcctatgcc
attgcctcttccatcgtgtccttctacgttcccctggtgatcatggtcttcgtctactcc
agggtctttcaggaggccaaaaggcagctccagaagattgacaaatctgagggccgcttc
catgtccagaaccttagccaggtggagcaggatgggcggacggggcatggactccgcaga
tcttccaagttctgcttgaaggagcacaaagccctcaagacgttaggcatcatcatgggc
actttcaccctctgctggctgcccttcttcatcgttaacattgtgcatgtgatccaggat
aacctcatccgtaaggaagtttacatcctcctaaattggataggctatgtcaattctggt
ttcaatccccttatctactgccggagcccagatttcaggattgccttccaggagcttctg
tgcctgcgcaggtcttctttgaaggcctatgggaatggctactccagcaacggcaacaca
ggggagcagagtggatatcacgtggaacaggagaaagaaaataaactgctgtgtgaagac
ctcccaggcacggaagactttgtgggccatcaaggtactgtgcctagcgataacattgat
tcacaagggaggaattgtagtacaaatgactcactgctgtaa

KEGG   Homo sapiens (human): 1813Help
Entry
1813              CDS       T01001                                 

Gene name
DRD2, D2DR, D2R
Definition
(RefSeq) dopamine receptor D2
  KO
K04145  dopamine receptor D2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04015  Rap1 signaling pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction
hsa04728  Dopaminergic synapse
hsa05012  Parkinson disease
hsa05030  Cocaine addiction
hsa05034  Alcoholism
Disease
H01611  Alcohol dependence
Drug target
Acepromazine (DG00870): D02604 D07065
Acetophenazine (DG00878): D00788
Alentemol hydrobromide: D02634
Alizapride (DG00058): D07102 D07563
Amisulpride: D07310
Aplindore fumarate: D03214
Apomorphine (DG00486): D02004 D07460
Aripiprazole (DG00906): D01164 D10355 D10364 D10516
Asenapine: D02995
Benperidol: D02627
Bifeprunox (DG01304): D06566 D06567
Blonanserin: D01176
Brexpiprazole: D10309
Bromocriptine (DG00452): D00780 D03165
Bromopride: D07101
Bromperidol (DG00890): D01101 D02626
Buspirone (DG00913): D00702 D07593
Butaclamol hydrochloride: D02641
Cabergoline: D00987
Cariprazine (DG01305): D09876 D09997
Carphenazine maleate: D02644
Carvotroline hydrochloride: D02645
Chlorpromazine (DG00867): D00270 D00789 D03274 D04034 D09819
Chlorprothixene (DG00894): D00790 D02162 D07686 D07687
Ciladopa hydrochloride: D03494
Clebopride (DG00059): D01742 D03534
Clocapramine (DG01313): D02371 D07718
Clopenthixol: D02613
Dexpramipexole (DG01331): D09886 D09887
Dihydroergocryptine (DG01329): D07835
Dihydroergocryptine mesylate: D07836
Domperidone (DG00057): D01745 D07868
Dopamine (DG00213): D00633 D07870
Dopexamine (DG00222): D03891 D03892
Droperidol: D00308
Etilevodopa: D04097
Flupentixol (DG00893): D01044 D02236 D07976
Fluphenazine (DG00874): D00791 D00792 D00793 D02163 D07977
Haloperidol (DG00885): D00136 D01898 D08035
Ibopamine (DG00223): D04488 D08057
Iloperidone: D02666
Itopride (DG01395): D02729 D08094
Lergotrile (DG01319): D04693 D04694
Levodopa: D00059
Levomepromazine (DG00868): D00403 D01520 D02248
Levosulpiride: D07312
Lisuride (DG00453): D01462 D08132
Loxapine (DG00897): D00794 D02340 D08148
Lumateperone (DG02937): D11169 D11170
Lurasidone: D04820
Mazapertine succinate: D02670
Melperone (DG00887): D07309 D08172
Mesoridazine (DG00883): D00795 D02671
Methoxypromazine maleate: D02605
Metoclopramide (DG00055): D00726 D02213 D05008
Metopimazine: D05010
Molindone (DG00891): D00796 D08226
Moperone (DG00888): D01105 D02623
Mosapramine (DG00905): D01548 D08235
Naxagolide hydrochloride: D05124
Nemonapride: D01468
Ocaperidone: D02675
Olanzapine (DG00898): D00454 D06623
Opipramol (DG00930): D01477 D08297
Oxiperomide: D02676
Paliperidone (DG00907): D05339 D05340
Pardoprunox (DG01324): D09366 D09397
Perazine (DG00881): D01412 D01860 D02608
Pergolide (DG00861): D00502 D08339
Periciazine: D01485
Perospirone hydrochloride hydrate: D02372
Perphenazine (DG00875): D00503 D02037 D04038 D04965 D08341 D08342
Pimozide: D00560
Pipamperone (DG00889): D01482 D02622
Pipotiazine (DG00884): D02680 D08385
Piquindone hydrochloride: D02681
Piribedil: D07305
Pramipexole (DG00863): D00559 D05575
Pridopidine (DG01325): D09953 D09954
Prochlorperazine (DG00876): D00479 D00493 D02022 D02609
Promazine (DG00869): D00797 D08430
Quetiapine (DG00899): D00458 D08456
Quinagolide (DG00454): D07217 D08457
Quinelorane hydrochloride: D05677
Quinpirole hydrochloride: D05682
Raclopride C11: D05690
Remoxipride (DG00902): D02682 D02683
Risperidone: D00426
Ropinirole (DG00862): D00784 D08489
Rotigotine: D05768
Sarizotan hydrochloride: D05804
Sertindole: D00561
Sibenadet hydrochloride: D05832
Spiperone: D01051
Sulpiride: D01226
Sultopride (DG00900): D02208 D08549
Talipexole (DG01326): D01505 D08558
Terguride: D01348
Thiethylperazine (DG01102): D01130 D02354 D02610
Thioproperazine (DG00879): D01447 D08585
Thioridazine (DG00882): D00373 D00798
Tiapride (DG00901): D01522 D08590
Timiperone: D02035
Tiospirone hydrochloride: D02688
Tiotixene (DG00895): D00374 D02612
Trifluoperazine (DG00877): D00799 D01448 D08636
Trifluperidol (DG00886): D02625 D08637
Triflupromazine (DG00871): D00390 D00800
Zicronapine (DG01539): D10329 D10495
Ziprasidone (DG00892): D01939 D02100 D08687
Zotepine: D01321
Zuclopenthixol (DG00896): D03556 D08691 D08692 D08693
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    1813 (DRD2)
   04024 cAMP signaling pathway
    1813 (DRD2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    1813 (DRD2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    1813 (DRD2)
 09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    1813 (DRD2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    1813 (DRD2)
  09165 Substance dependence
   05030 Cocaine addiction
    1813 (DRD2)
   05034 Alcoholism
    1813 (DRD2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    1813 (DRD2)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Dopamine
    1813 (DRD2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srv 7tm_4 DUF2207 Stevor RIFIN
Motif
Other DBs
NCBI-GeneID: 1813
NCBI-ProteinID: NP_000786
OMIM: 126450
HGNC: 3023
Ensembl: ENSG00000149295
Vega: OTTHUMG00000167717
Pharos: P14416(Tclin)
UniProt: P14416 A0A024R3C5
LinkDB All DBs
Position
11q23.2
AA seq 443 aa AA seqDB search
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
NT seq 1332 nt NT seq  +upstreamnt  +downstreamnt
atggatccactgaatctgtcctggtatgatgatgatctggagaggcagaactggagccgg
cccttcaacgggtcagacgggaaggcggacagaccccactacaactactatgccacactg
ctcaccctgctcatcgctgtcatcgtcttcggcaacgtgctggtgtgcatggctgtgtcc
cgcgagaaggcgctgcagaccaccaccaactacctgatcgtcagcctcgcagtggccgac
ctcctcgtcgccacactggtcatgccctgggttgtctacctggaggtggtaggtgagtgg
aaattcagcaggattcactgtgacatcttcgtcactctggacgtcatgatgtgcacggcg
agcatcctgaacttgtgtgccatcagcatcgacaggtacacagctgtggccatgcccatg
ctgtacaatacgcgctacagctccaagcgccgggtcaccgtcatgatctccatcgtctgg
gtcctgtccttcaccatctcctgcccactcctcttcggactcaataacgcagaccagaac
gagtgcatcattgccaacccggccttcgtggtctactcctccatcgtctccttctacgtg
cccttcattgtcaccctgctggtctacatcaagatctacattgtcctccgcagacgccgc
aagcgagtcaacaccaaacgcagcagccgagctttcagggcccacctgagggctccacta
aagggcaactgtactcaccccgaggacatgaaactctgcaccgttatcatgaagtctaat
gggagtttcccagtgaacaggcggagagtggaggctgcccggcgagcccaggagctggag
atggagatgctctccagcaccagcccacccgagaggacccggtacagccccatcccaccc
agccaccaccagctgactctccccgacccgtcccaccatggtctccacagcactcccgac
agccccgccaaaccagagaagaatgggcatgccaaagaccaccccaagattgccaagatc
tttgagatccagaccatgcccaatggcaaaacccggacctccctcaagaccatgagccgt
aggaagctctcccagcagaaggagaagaaagccactcagatgctcgccattgttctcggc
gtgttcatcatctgctggctgcccttcttcatcacacacatcctgaacatacactgtgac
tgcaacatcccgcctgtcctgtacagcgccttcacgtggctgggctatgtcaacagcgcc
gtgaaccccatcatctacaccaccttcaacattgagttccgcaaggccttcctgaagatc
ctccactgctga

KEGG   Homo sapiens (human): 1909Help
Entry
1909              CDS       T01001                                 

Gene name
EDNRA, ET-A, ETA, ETA-R, ETAR, ETRA, MFDA, hET-AR
Definition
(RefSeq) endothelin receptor type A
  KO
K04197  endothelin receptor type A
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04924  Renin secretion
hsa05200  Pathways in cancer
Disease
H02126  Mandibulofacial dysostosis with alopecia
Drug target
Ambrisentan: D07077
Aprocitentan: D11441
Atrasentan hydrochloride: D03009
Bosentan (DG00266): D01227 D07538
Clazosentan sodium: D07682
Edonentan: D03953
Fandosentan potassium: D04128
Macitentan: D10135
Sitaxentan (DG00267): D07171 D08517
Zibotentan: D07741
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    1909 (EDNRA)
   04024 cAMP signaling pathway
    1909 (EDNRA)
   04022 cGMP-PKG signaling pathway
    1909 (EDNRA)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    1909 (EDNRA)
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    1909 (EDNRA)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    1909 (EDNRA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1909 (EDNRA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    1909 (EDNRA)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Endothelin
    1909 (EDNRA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx
Motif
Other DBs
NCBI-GeneID: 1909
NCBI-ProteinID: NP_001948
OMIM: 131243
HGNC: 3179
Ensembl: ENSG00000151617
Vega: OTTHUMG00000161354
Pharos: P25101(Tclin)
UniProt: P25101
LinkDB All DBs
Position
4q31.22-q31.23
AA seq 427 aa AA seqDB search
METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP
SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS
VDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCM
LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM
NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS
SHKDSMN
NT seq 1284 nt NT seq  +upstreamnt  +downstreamnt
atggaaaccctttgcctcagggcatccttttggctggcactggttggatgtgtaatcagt
gataatcctgagagatacagcacaaatctaagcaatcatgtggatgatttcaccactttt
cgtggcacagagctcagcttcctggttaccactcatcaacccactaatttggtcctaccc
agcaatggctcaatgcacaactattgcccacagcagactaaaattacttcagctttcaaa
tacattaacactgtgatatcttgtactattttcatcgtgggaatggtggggaatgcaact
ctgctcaggatcatttaccagaacaaatgtatgaggaatggccccaacgcgctgatagcc
agtcttgcccttggagaccttatctatgtggtcattgatctccctatcaatgtatttaag
ctgctggctgggcgctggccttttgatcacaatgactttggcgtatttctttgcaagctg
ttcccctttttgcagaagtcctcggtggggatcaccgtcctcaacctctgcgctcttagt
gttgacaggtacagagcagttgcctcctggagtcgtgttcagggaattgggattcctttg
gtaactgccattgaaattgtctccatctggatcctgtcctttatcctggccattcctgaa
gcgattggcttcgtcatggtaccctttgaatataggggtgaacagcataaaacctgtatg
ctcaatgccacatcaaaattcatggagttctaccaagatgtaaaggactggtggctcttc
gggttctatttctgtatgcccttggtgtgcactgcgatcttctacaccctcatgacttgt
gagatgttgaacagaaggaatggcagcttgagaattgccctcagtgaacatcttaagcag
cgtcgagaagtggcaaaaacagttttctgcttggttgtaatttttgctctttgctggttc
cctcttcatttaagccgtatattgaagaaaactgtgtataacgagatggacaagaaccga
tgtgaattacttagtttcttactgctcatggattacatcggtattaacttggcaaccatg
aattcatgtataaaccccatagctctgtattttgtgagcaagaaatttaaaaattgtttc
cagtcatgcctctgctgctgctgttaccagtccaaaagtctgatgacctcggtccccatg
aacggaacaagcatccagtggaagaaccacgatcaaaacaaccacaacacagaccggagc
agccataaggacagcatgaactga

KEGG   Homo sapiens (human): 2550Help
Entry
2550              CDS       T01001                                 

Gene name
GABBR1, GABABR1, GABBR1-3, GB1, GPRC3A
Definition
(RefSeq) gamma-aminobutyric acid type B receptor subunit 1
  KO
K04615  gamma-aminobutyric acid type B receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse
hsa04742  Taste transduction
hsa04915  Estrogen signaling pathway
hsa04929  GnRH secretion
hsa05032  Morphine addiction
Drug target
Aminobutyric acid: D00058
Arbaclofen (DG01354): D08861 D09791
Baclofen: D00241
Progabide: D05621
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    2550 (GABBR1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    2550 (GABBR1)
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    2550 (GABBR1)
   04915 Estrogen signaling pathway
    2550 (GABBR1)
  09156 Nervous system
   04727 GABAergic synapse
    2550 (GABBR1)
  09157 Sensory system
   04742 Taste transduction
    2550 (GABBR1)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    2550 (GABBR1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    2550 (GABBR1)
G protein-coupled receptors [BR:hsa04030]
 Metabotropic glutamate receptor family
  GABA
   2550 (GABBR1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: ANF_receptor 7tm_3 Peripla_BP_6 Sushi UPF0242 DUF3995 PKcGMP_CC COX1
Motif
Other DBs
NCBI-GeneID: 2550
NCBI-ProteinID: NP_001461
OMIM: 603540
HGNC: 4070
Ensembl: ENSG00000204681
Vega: OTTHUMG00000031095
Pharos: Q9UBS5(Tclin)
UniProt: Q9UBS5 A0A1U9X7R0 Q59HG8
LinkDB All DBs
Structure
PDB: 

Position
6p22.1
AA seq 961 aa AA seqDB search
MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD
YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLP
ALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG
GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKI
ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKL
FEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDAR
IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE
GHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALA
LNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIE
QLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSS
LGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFP
FVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGM
DVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLL
LLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLA
IVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEK
IIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLY
K
NT seq 2886 nt NT seq  +upstreamnt  +downstreamnt
atgttgctgctgctgctactggcgccactcttcctccgccccccgggcgcgggcggggcg
cagacccccaacgccacctcagaaggttgccagatcatacacccgccctgggaagggggc
atcaggtaccggggcctgactcgggaccaggtgaaggctatcaacttcctgccagtggac
tatgagattgagtatgtgtgccggggggagcgcgaggtggtggggcccaaggtccgcaag
tgcctggccaacggctcctggacagatatggacacacccagccgctgtgtccgaatctgc
tccaagtcttatttgaccctggaaaatgggaaggttttcctgacgggtggggacctccca
gctctggacggagcccgggtggatttccggtgtgaccccgacttccatctggtgggcagc
tcccggagcatctgtagtcagggccagtggagcacccccaagccccactgccaggtgaat
cgaacgccacactcagaacggcgcgcagtgtacatcggggcactgtttcccatgagcggg
ggctggccagggggccaggcctgccagcccgcggtggagatggcgctggaggacgtgaat
agccgcagggacatcctgccggactatgagctcaagctcatccaccacgacagcaagtgt
gatccaggccaagccaccaagtacctatatgagctgctctacaacgaccctatcaagatc
atccttatgcctggctgcagctctgtctccacgctggtggctgaggctgctaggatgtgg
aacctcattgtgctttcctatggctccagctcaccagccctgtcaaaccggcagcgtttc
cccactttcttccgaacgcacccatcagccacactccacaaccctacccgcgtgaaactc
tttgaaaagtggggctggaagaagattgctaccatccagcagaccactgaggtcttcact
tcgactctggacgacctggaggaacgagtgaaggaggctggaattgagattactttccgc
cagagtttcttctcagatccagctgtgcccgtcaaaaacctgaagcgccaggatgcccga
atcatcgtgggacttttctatgagactgaagcccggaaagttttttgtgaggtgtacaag
gagcgtctctttgggaagaagtacgtctggttcctcattgggtggtatgctgacaattgg
ttcaagatctacgacccttctatcaactgcacagtggatgagatgactgaggcggtggag
ggccacatcacaactgagattgtcatgctgaatcctgccaatacccgcagcatttccaac
atgacatcccaggaatttgtggagaaactaaccaagcgactgaaaagacaccctgaggag
acaggaggcttccaggaggcaccgctggcctatgatgccatctgggccttggcactggcc
ctgaacaagacatctggaggaggcggccgttctggtgtgcgcctggaggacttcaactac
aacaaccagaccattaccgaccaaatctaccgggcaatgaactcttcgtcctttgagggt
gtctctggccatgtggtgtttgatgccagcggctctcggatggcatggacgcttatcgag
cagcttcagggtggcagctacaagaagattggctactatgacagcaccaaggatgatctt
tcctggtccaaaacagataaatggattggagggtcccccccagctgaccagaccctggtc
atcaagacattccgcttcctgtcacagaaactctttatctccgtctcagttctctccagc
ctgggcattgtcctagctgttgtctgtctgtcctttaacatctacaactcacatgtccgt
tatatccagaactcacagcccaacctgaacaacctgactgctgtgggctgctcactggct
ttagctgctgtcttccccctggggctcgatggttaccacattgggaggaaccagtttcct
ttcgtctgccaggcccgcctctggctcctgggcctgggctttagtctgggctacggttcc
atgttcaccaagatttggtgggtccacacggtcttcacaaagaaggaagaaaagaaggag
tggaggaagactctggaaccctggaagctgtatgccacagtgggcctgctggtgggcatg
gatgtcctcactctcgccatctggcagatcgtggaccctctgcaccggaccattgagaca
tttgccaaggaggaacctaaggaagatattgacgtctctattctgccccagctggagcat
tgcagctccaggaagatgaatacatggcttggcattttctatggttacaaggggctgctg
ctgctgctgggaatcttccttgcttatgagaccaagagtgtgtccactgagaagatcaat
gatcaccgggctgtgggcatggctatctacaatgtggcagtcctgtgcctcatcactgct
cctgtcaccatgattctgtccagccagcaggatgcagcctttgcctttgcctctcttgcc
atagttttctcctcctatatcactcttgttgtgctctttgtgcccaagatgcgcaggctg
atcacccgaggggaatggcagtcggaggcgcaggacaccatgaagacagggtcatcgacc
aacaacaacgaggaggagaagtcccggctgttggagaaggagaaccgtgaactggaaaag
atcattgctgagaaagaggagcgtgtctctgaactgcgccatcaactccagtctcggcag
cagctccgctcccggcgccacccaccgacacccccagaaccctctgggggcctgcccagg
ggaccccctgagccccccgaccggcttagctgtgatgggagtcgagtgcatttgctttat
aagtga

KEGG   Homo sapiens (human): 2693Help
Entry
2693              CDS       T01001                                 

Gene name
GHSR, GHDP
Definition
(RefSeq) growth hormone secretagogue receptor
  KO
K04284  growth hormone secretagogue receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04935  Growth hormone synthesis, secretion and action
Drug target
Anamorelin hydrochloride: D08856
Capromorelin tartrate: D03373
Macimorelin (DG01879): D10562 D10563
Pralmorelin dihydrochloride: D02040
Relamorelin: D10660
Rismorelin porcine: D05734
Ulimorelin (DG01338): D09981 D09982
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    2693 (GHSR)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    2693 (GHSR)
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    2693 (GHSR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    2693 (GHSR)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Ghrelin
    2693 (GHSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srw 7TM_GPCR_Srv 7TM_GPCR_Srsx 7TM_GPCR_Srx 7tm_4
Motif
Other DBs
NCBI-GeneID: 2693
NCBI-ProteinID: NP_940799
OMIM: 601898
HGNC: 4267
Ensembl: ENSG00000121853
Vega: OTTHUMG00000156946
Pharos: Q92847(Tclin)
UniProt: Q92847
LinkDB All DBs
Position
3q26.31
AA seq 366 aa AA seqDB search
MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT
ESSINT
NT seq 1101 nt NT seq  +upstreamnt  +downstreamnt
atgtggaacgcgacgcccagcgaagagccggggttcaacctcacactggccgacctggac
tgggatgcttcccccggcaacgactcgctgggcgacgagctgctgcagctcttccccgcg
ccgctgctggcgggcgtcacagccacctgcgtggcactcttcgtggtgggcatcgctggc
aacctgctcaccatgctggtggtgtcgcgcttccgcgagctgcgcaccaccaccaacctc
tacctgtccagcatggccttctccgatctgctcatcttcctctgcatgcccctggacctc
gttcgcctctggcagtaccggccctggaacttcggcgacctcctctgcaaactcttccaa
ttcgtcagtgagagctgcacctacgccacggtgctcaccatcacagcgctgagcgtcgag
cgctacttcgccatctgcttcccactccgggccaaggtggtggtcaccaaggggcgggtg
aagctggtcatcttcgtcatctgggccgtggccttctgcagcgccgggcccatcttcgtg
ctagtcggggtggagcacgagaacggcaccgacccttgggacaccaacgagtgccgcccc
accgagtttgcggtgcgctctggactgctcacggtcatggtgtgggtgtccagcatcttc
ttcttccttcctgtcttctgtctcacggtcctctacagtctcatcggcaggaagctgtgg
cggaggaggcgcggcgatgctgtcgtgggtgcctcgctcagggaccagaaccacaagcaa
accgtgaaaatgctggctgtagtggtgtttgccttcatcctctgctggctccccttccac
gtagggcgatatttattttccaaatcctttgagcctggctccttggagattgctcagatc
agccagtactgcaacctcgtgtcctttgtcctcttctacctcagtgctgccatcaacccc
attctgtacaacatcatgtccaagaagtaccgggtggcagtgttcagacttctgggattc
gaacccttctcccagagaaagctctccactctgaaagatgaaagttctcgggcctggaca
gaatctagtattaatacatga

KEGG   Homo sapiens (human): 27198Help
Entry
27198             CDS       T01001                                 

Gene name
HCAR1, FKSG80, GPR104, GPR81, HCA1, LACR1, TA-GPCR, TAGPCR
Definition
(RefSeq) hydroxycarboxylic acid receptor 1
  KO
K08401  hydroxycarboxylic acid receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    27198 (HCAR1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    27198 (HCAR1)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Others
   Hydroxy-carboxylic acid
    27198 (HCAR1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srv DUF4965
Motif
Other DBs
NCBI-GeneID: 27198
NCBI-ProteinID: NP_115943
OMIM: 606923
HGNC: 4532
Ensembl: ENSG00000196917
Vega: OTTHUMG00000168863
Pharos: Q9BXC0(Tbio)
UniProt: Q9BXC0
LinkDB All DBs
Position
12q24.31
AA seq 346 aa AA seqDB search
MYNGSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVA
DFLLMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHP
HHAVNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIM
FQLEFFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLPSVSAR
LYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKPK
QPGHSKTQRPEEMPISNLGRRSCISVANSFQSQSDGQWDPHIVEWH
NT seq 1041 nt NT seq  +upstreamnt  +downstreamnt
atgtacaacgggtcgtgctgccgcatcgagggggacaccatctcccaggtgatgccgccg
ctgctcattgtggcctttgtgctgggcgcactaggcaatggggtcgccctgtgtggtttc
tgcttccacatgaagacctggaagcccagcactgtttaccttttcaatttggccgtggct
gatttcctccttatgatctgcctgccttttcggacagactattacctcagacgtagacac
tgggcttttggggacattccctgccgagtggggctcttcacgttggccatgaacagggcc
gggagcatcgtgttccttacggtggtggctgcggacaggtatttcaaagtggtccacccc
caccacgcggtgaacactatctccacccgggtggcggctggcatcgtctgcaccctgtgg
gccctggtcatcctgggaacagtgtatcttttgctggagaaccatctctgcgtgcaagag
acggccgtctcctgtgagagcttcatcatggagtcggccaatggctggcatgacatcatg
ttccagctggagttctttatgcccctcggcatcatcttattttgctccttcaagattgtt
tggagcctgaggcggaggcagcagctggccagacaggctcggatgaagaaggcgacccgg
ttcatcatggtggtggcaattgtgttcatcacatgctacctgcccagcgtgtctgctaga
ctctatttcctctggacggtgccctcgagtgcctgcgatccctctgtccatggggccctg
cacataaccctcagcttcacctacatgaacagcatgctggatcccctggtgtattatttt
tcaagcccctcctttcccaaattctacaacaagctcaaaatctgcagtctgaaacccaag
cagccaggacactcaaaaacacaaaggccggaagagatgccaatttcgaacctcggtcgc
aggagttgcatcagtgtggcaaatagtttccaaagccagtctgatgggcaatgggatccc
cacattgttgagtggcactga

KEGG   Homo sapiens (human): 2867Help
Entry
2867              CDS       T01001                                 

Gene name
FFAR2, FFA2R, GPR43
Definition
(RefSeq) free fatty acid receptor 2
  KO
K04328  free fatty acid receptor 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    2867 (FFAR2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    2867 (FFAR2)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Lipid
   Free fatty acid
    2867 (FFAR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srv TAS2R 7TM_GPCR_Srx 7TM_GPCR_Srsx
Motif
Other DBs
NCBI-GeneID: 2867
NCBI-ProteinID: NP_005297
OMIM: 603823
HGNC: 4501
Ensembl: ENSG00000126262
Vega: OTTHUMG00000183303
Pharos: O15552(Tchem)
UniProt: O15552 C6KYL4
LinkDB All DBs
Position
19q13.12
AA seq 330 aa AA seqDB search
MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL
LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS
RRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVR
LELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNV
SHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLG
RRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
NT seq 993 nt NT seq  +upstreamnt  +downstreamnt
atgctgccggactggaagagctccttgatcctcatggcttacatcatcatcttcctcact
ggcctccctgccaacctcctggccctgcgggcctttgtggggcggatccgccagccccag
cctgcacctgtgcacatcctcctgctgagcctgacgctggccgacctcctcctgctgctg
ctgctgcccttcaagatcatcgaggctgcgtcgaacttccgctggtacctgcccaaggtc
gtctgcgccctcacgagttttggcttctacagcagcatctactgcagcacgtggctcctg
gcgggcatcagcatcgagcgctacctgggagtggctttccccgtgcagtacaagctctcc
cgccggcctctgtatggagtgattgcagctctggtggcctgggttatgtcctttggtcac
tgcaccatcgtgatcatcgttcaatacttgaacacgactgagcaggtcagaagtggcaat
gaaattacctgctacgagaacttcaccgataaccagttggacgtggtgctgcccgtgcgg
ctggagctgtgcctggtgctcttcttcatccccatggcagtcaccatcttctgctactgg
cgttttgtgtggatcatgctctcccagccccttgtgggggcccagaggcggcgccgagcc
gtggggctggctgtggtgacgctgctcaatttcctggtgtgcttcggaccttacaacgtg
tcccacctggtggggtatcaccagagaaaaagcccctggtggcggtcaatagccgtggtg
ttcagttcactcaacgccagtctggaccccctgctcttctatttctcttcttcagtggtg
cgcagggcatttgggagagggctgcaggtgctgcggaatcagggctcctccctgttggga
cgcagaggcaaagacacagcagaggggacaaatgaggacaggggtgtgggtcaaggagaa
gggatgccaagttcggacttcactacagagtag

KEGG   Homo sapiens (human): 3350Help
Entry
3350              CDS       T01001                                 

Gene name
HTR1A, 5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD
Definition
(RefSeq) 5-hydroxytryptamine receptor 1A
  KO
K04153  5-hydroxytryptamine receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse
hsa04742  Taste transduction
Drug target
Adatanserin hydrochloride: D02767
Aripiprazole (DG00906): D01164 D10355 D10364 D10516
Asenapine: D02995
Bifeprunox (DG01304): D06566 D06567
Binospirone mesylate: D03121
Brexpiprazole: D10309
Buspirone (DG00913): D00702 D07593
Cariprazine (DG01305): D09876 D09997
Cinitapride (DG01520): D07700 D07701
Eptapirone: D02576
Ergot alkaloids: D07906
Ergotamine (DG00834): D00679
Flesinoxan: D02568
Flibanserin: D02577
Gepirone: D04314
Indorenate hydrochloride: D04533
Ipsapirone hydrochloride: D04611
Lecozotan hydrochloride: D04683
Methysergide (DG00835): D00681 D02357
Naluzotan (DG01279): D09358 D09359
Pardoprunox (DG01324): D09366 D09397
Pipotiazine (DG00884): D02680 D08385
Pizotifen (DG00842): D05523 D08397
Sarizotan hydrochloride: D05804
Sunepitron hydrochloride: D02569
Tandospirone (DG01306): D01992 D08561
Tiospirone hydrochloride: D02688
Vilazodone (DG00964): D09698 D09699
Vortioxetine (DG00965): D10184 D10185
Xaliproden (DG01008): D01537 D06327
Zalospirone hydrochloride: D06354
Zotepine: D01321
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    3350 (HTR1A)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    3350 (HTR1A)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    3350 (HTR1A)
  09157 Sensory system
   04742 Taste transduction
    3350 (HTR1A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    3350 (HTR1A)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Serotonin
    3350 (HTR1A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7tm_4
Motif
Other DBs
NCBI-GeneID: 3350
NCBI-ProteinID: NP_000515
OMIM: 109760
HGNC: 5286
Ensembl: ENSG00000178394
Vega: OTTHUMG00000162279
Pharos: P08908(Tclin)
UniProt: P08908 Q5ZGX3 A8K5W4
LinkDB All DBs
Position
5q12.3
AA seq 422 aa AA seqDB search
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
NT seq 1269 nt NT seq  +upstreamnt  +downstreamnt
atggatgtgctcagccctggtcagggcaacaacaccacatcaccaccggctccctttgag
accggcggcaacactactggtatctccgacgtgaccgtcagctaccaagtgatcacctct
ctgctgctgggcacgctcatcttctgcgcggtgctgggcaatgcgtgcgtggtggctgcc
atcgccttggagcgctccctgcagaacgtggccaattatcttattggctctttggcggtc
accgacctcatggtgtcggtgttggtgctgcccatggccgcgctgtatcaggtgctcaac
aagtggacactgggccaggtaacctgcgacctgttcatcgccctcgacgtgctgtgctgc
acctcatccatcttgcacctgtgcgccatcgcgctggacaggtactgggccatcacggac
cccatcgactacgtgaacaagaggacgccccggcgcgccgctgcgctcatctcgctcact
tggcttattggcttcctcatctctatcccgcccatgctgggctggcgcaccccggaagac
cgctcggaccccgacgcatgcaccattagcaaggatcatggctacactatctattccacc
tttggagctttctacatcccgctgctgctcatgctggttctctatgggcgcatattccga
gctgcgcgcttccgcatccgcaagacggtcaaaaaggtggagaagaccggagcggacacc
cgccatggagcatctcccgccccgcagcccaagaagagtgtgaatggagagtcggggagc
aggaactggaggctgggcgtggagagcaaggctgggggtgctctgtgcgccaatggcgcg
gtgaggcaaggtgacgatggcgccgccctggaggtgatcgaggtgcaccgagtgggcaac
tccaaagagcacttgcctctgcccagcgaggctggtcctaccccttgtgcccccgcctct
ttcgagaggaaaaatgagcgcaacgccgaggcgaagcgcaagatggccctggcccgagag
aggaagacagtgaagacgctgggcatcatcatgggcaccttcatcctctgctggctgccc
ttcttcatcgtggctcttgttctgcccttctgcgagagcagctgccacatgcccaccctg
ttgggcgccataatcaattggctgggctactccaactctctgcttaaccccgtcatttac
gcatacttcaacaaggactttcaaaacgcgtttaagaagatcattaagtgtaagttctgc
cgccagtga

KEGG   Homo sapiens (human): 3351Help
Entry
3351              CDS       T01001                                 

Gene name
HTR1B, 5-HT-1B, 5-HT-1D-beta, 5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
Definition
(RefSeq) 5-hydroxytryptamine receptor 1B
  KO
K04153  5-hydroxytryptamine receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse
hsa04742  Taste transduction
Drug target
Almotriptan (DG00839): D02824 D02825
Alniditan dihydrochloride: D02826
Avitriptan fumarate: D03014
Cinitapride (DG01520): D07700 D07701
Dihydroergotamine (DG00833): D02211 D07837 D07838
Eletriptan (DG00840): D01973 D07887 D11617
Elzasonan (DG01314): D03982 D03983
Ergot alkaloids: D07906
Ergotamine (DG00834): D00679
Frovatriptan (DG00841): D04264 D07997
Indorenate hydrochloride: D04533
Naratriptan (DG00837): D00674 D08255
Pizotifen (DG00842): D05523 D08397
Rizatriptan (DG00838): D00675 D05740 D08485
Sumatriptan (DG00836): D00451 D00676
Zolmitriptan: D00415
Zotepine: D01321
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    3351 (HTR1B)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    3351 (HTR1B)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    3351 (HTR1B)
  09157 Sensory system
   04742 Taste transduction
    3351 (HTR1B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    3351 (HTR1B)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Serotonin
    3351 (HTR1B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7tm_4
Motif
Other DBs
NCBI-GeneID: 3351
NCBI-ProteinID: NP_000854
OMIM: 182131
HGNC: 5287
Ensembl: ENSG00000135312
Vega: OTTHUMG00000015066
Pharos: P28222(Tclin)
UniProt: P28222 X5D7I5 A8K215
LinkDB All DBs
Structure
PDB: 

Position
6q14.1
AA seq 390 aa AA seqDB search
MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALIT
LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLE
KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL
NSLINPIIYTMSNEDFKQAFHKLIRFKCTS
NT seq 1173 nt NT seq  +upstreamnt  +downstreamnt
atggaggaaccgggtgctcagtgcgctccaccgccgcccgcgggctccgagacctgggtt
cctcaagccaacttatcctctgctccctcccaaaactgcagcgccaaggactacatttac
caggactccatctccctaccctggaaagtactgctggttatgctattggcgctcatcacc
ttggccaccacgctctccaatgcctttgtgattgccacagtgtaccggacccggaaactg
cacaccccggctaactacctgatcgcctctctggcggtcaccgacctgcttgtgtccatc
ctggtgatgcccatcagcaccatgtacactgtcaccggccgctggacactgggccaggtg
gtctgtgacttctggctgtcgtcggacatcacttgttgcactgcctccatcctgcacctc
tgtgtcatcgccctggaccgctactgggccatcacggacgccgtggagtactcagctaaa
aggactcccaagagggcggcggtcatgatcgcgctggtgtgggtcttctccatctctatc
tcgctgccgcccttcttctggcgtcaggctaaggccgaagaggaggtgtcggaatgcgtg
gtgaacaccgaccacatcctctacacggtctactccacggtgggtgctttctacttcccc
accctgctcctcatcgccctctatggccgcatctacgtagaagcccgctcccggattttg
aaacagacgcccaacaggaccggcaagcgcttgacccgagcccagctgataaccgactcc
cccgggtccacgtcctcggtcacctctattaactcgcgggttcccgacgtgcccagcgaa
tccggatctcctgtgtatgtgaaccaagtcaaagtgcgagtctccgacgccctgctggaa
aagaagaaactcatggccgctagggagcgcaaagccaccaagaccctagggatcattttg
ggagcctttattgtgtgttggctacccttcttcatcatctccctagtgatgcctatctgc
aaagatgcctgctggttccacctagccatctttgacttcttcacatggctgggctatctc
aactccctcatcaaccccataatctataccatgtccaatgaggactttaaacaagcattc
cataaactgatacgttttaagtgcacaagttga

KEGG   Homo sapiens (human): 3352Help
Entry
3352              CDS       T01001                                 

Gene name
HTR1D, 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4
Definition
(RefSeq) 5-hydroxytryptamine receptor 1D
  KO
K04153  5-hydroxytryptamine receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse
hsa04742  Taste transduction
Disease
H01703  Eating Disorders
Drug target
Almotriptan (DG00839): D02824 D02825
Alniditan dihydrochloride: D02826
Avitriptan fumarate: D03014
Cinitapride (DG01520): D07700 D07701
Dihydroergotamine (DG00833): D02211 D07837 D07838
Eletriptan (DG00840): D01973 D07887 D11617
Elzasonan (DG01314): D03982 D03983
Ergot alkaloids: D07906
Ergotamine (DG00834): D00679
Frovatriptan (DG00841): D04264 D07997
Indorenate hydrochloride: D04533
Naratriptan (DG00837): D00674 D08255
Pizotifen (DG00842): D05523 D08397
Rizatriptan (DG00838): D00675 D05740 D08485
Sumatriptan (DG00836): D00451 D00676
Zolmitriptan: D00415
Zotepine: D01321
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    3352 (HTR1D)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    3352 (HTR1D)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    3352 (HTR1D)
  09157 Sensory system
   04742 Taste transduction
    3352 (HTR1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    3352 (HTR1D)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Serotonin
    3352 (HTR1D)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx
Motif
Other DBs
NCBI-GeneID: 3352
NCBI-ProteinID: NP_000855
OMIM: 182133
HGNC: 5289
Ensembl: ENSG00000179546
Vega: OTTHUMG00000003235
Pharos: P28221(Tclin)
UniProt: P28221
LinkDB All DBs
Position
1p36.12
AA seq 377 aa AA seqDB search
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
NT seq 1134 nt NT seq  +upstreamnt  +downstreamnt
atgtccccactgaaccagtcagcagaaggccttccccaggaggcctccaacagatccctg
aatgccacagaaacctcagaggcttgggatcccaggaccctccaggcgctcaagatctcc
cttgccgtggtcctttccgtcatcacactggccacagtcctctccaatgcctttgtactc
accaccatcttactcaccaggaagctccacacccctgccaactacctgattggctccctg
gccaccaccgacctcttggtttccatcttggtaatgcccatcagcatcgcctataccatc
acccacacctggaactttggccaaatcttgtgtgacatctggctgtcctctgacatcacg
tgctgcacagcctccatcctgcatctctgtgtcattgctctggacaggtactgggcaatc
acagatgccctggaatacagtaaacgcaggacggctggccacgcggccaccatgatcgcc
attgtctgggccatctccatctgcatctccatccccccgctcttctggcggcaggccaag
gcccaggaggagatgtcggactgtctggtgaacacctctcagatctcctacaccatctac
tccacctgtggggccttctacattccctcggtgttgctcatcatcctatatggccggatc
taccgggctgcccggaaccgcatcctgaatccaccctcactctatgggaagcgcttcacc
acggcccacctcatcacaggctctgccgggtcctcgctctgctcgctcaactccagcctc
catgaggggcactcgcactcggctggctcccctctctttttcaaccacgtgaaaatcaag
cttgctgacagtgccctggaacgcaagaggatttctgctgctcgagaaaggaaagccact
aaaatcctgggcatcattctgggggcctttatcatctgctggctgcccttcttcgtggtg
tctctggtcctccccatctgccgggactcctgctggatccacccggcgctctttgacttc
ttcacctggctaggctatttaaactccctcatcaatccaataatctacactgtgtttaat
gaagagtttcggcaagcttttcagaaaattgtccctttccggaaggcctcctag

KEGG   Homo sapiens (human): 3354Help
Entry
3354              CDS       T01001                                 

Gene name
HTR1E, 5-HT1E
Definition
(RefSeq) 5-hydroxytryptamine receptor 1E
  KO
K04153  5-hydroxytryptamine receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse
hsa04742  Taste transduction
Drug target
Cinitapride (DG01520): D07700 D07701
Indorenate hydrochloride: D04533
Pizotifen (DG00842): D05523 D08397
Zotepine: D01321
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    3354 (HTR1E)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    3354 (HTR1E)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    3354 (HTR1E)
  09157 Sensory system
   04742 Taste transduction
    3354 (HTR1E)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    3354 (HTR1E)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Serotonin
    3354 (HTR1E)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srx 7TM_GPCR_Srsx 7tm_4
Motif
Other DBs
NCBI-GeneID: 3354
NCBI-ProteinID: NP_000856
OMIM: 182132
HGNC: 5291
Ensembl: ENSG00000168830
Vega: OTTHUMG00000015154
Pharos: P28566(Tchem)
UniProt: P28566
LinkDB All DBs
Position
6q14.3
AA seq 365 aa AA seqDB search
MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYL
ICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDR
YWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHV
IYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQ
TFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAF
ILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIR
CREHT
NT seq 1098 nt NT seq  +upstreamnt  +downstreamnt
atgaacatcacaaactgtaccacagaggccagcatggctataagacccaagaccatcact
gagaagatgctcatttgcatgactctggtggtcatcaccaccctcaccacgttgctgaac
ttggctgtgatcatggctattggcaccaccaagaagctccaccagcctgccaactaccta
atctgttctctggccgtgacggacctcctggtggcagtgctcgtcatgcccctgagcatc
atctacattgtcatggatcgctggaagcttgggtacttcctctgtgaggtgtggctgagt
gtggacatgacctgctgcacctgctccatcctccacctctgtgtcattgccctggacagg
tactgggccatcaccaatgctattgaatacgccaggaagaggacggccaagagggccgcg
ctgatgatccttaccgtctggaccatctccattttcatctccatgccccctctgttctgg
agaagccaccgccgcctaagccctccccctagtcagtgcaccatccagcacgaccatgtt
atctacaccatttactccacgctgggtgcgttttatatccccttgactttgatactgatt
ctctattaccggatttaccacgcggccaagagcctttaccagaaaaggggatcaagtcgg
cacttaagcaacagaagcacagatagccagaattcttttgcaagttgtaaacttacacag
actttctgtgtgtctgacttctccacctcagaccctaccacagagtttgaaaagttccat
gcctccatcaggatcccccccttcgacaatgatctagatcacccaggagaacgtcagcag
atctctagcaccagggaacggaaggcagcacgcatcctggggctgattctgggtgcattc
attttatcctggctgccatttttcatcaaagagttgattgtgggtctgagcatctacacc
gtgtcctcggaagtggccgactttctgacgtggctcggttatgtgaattctctgatcaac
cctctgctctatacgagttttaatgaagactttaagctggcttttaaaaagctcattaga
tgccgagagcatacttag

KEGG   Homo sapiens (human): 3355Help
Entry
3355              CDS       T01001                                 

Gene name
HTR1F, 5-HT-1F, 5-HT1F, 5HT6, HTR1EL, MR77
Definition
(RefSeq) 5-hydroxytryptamine receptor 1F
  KO
K04153  5-hydroxytryptamine receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse
hsa04742  Taste transduction
Drug target
Cinitapride (DG01520): D07700 D07701
Indorenate hydrochloride: D04533
Lasmiditan (DG01332): D10338 D10424
Pizotifen (DG00842): D05523 D08397
Zotepine: D01321
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    3355 (HTR1F)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    3355 (HTR1F)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    3355 (HTR1F)
  09157 Sensory system
   04742 Taste transduction
    3355 (HTR1F)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    3355 (HTR1F)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Serotonin
    3355 (HTR1F)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srv 7TM_GPCR_Srx Glycoprotein_G
Motif
Other DBs
NCBI-GeneID: 3355
NCBI-ProteinID: NP_000857
OMIM: 182134
HGNC: 5292
Ensembl: ENSG00000179097
Vega: OTTHUMG00000159008
Pharos: P30939(Tchem)
UniProt: P30939
LinkDB All DBs
Position
3p11.2-p11.1
AA seq 366 aa AA seqDB search
MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
LVRCRC
NT seq 1101 nt NT seq  +upstreamnt  +downstreamnt
atggatttcttaaattcatctgatcaaaacttgacctcagaggaactgttaaacagaatg
ccatccaaaattctggtgtccctcactctgtctgggctggcactgatgacaacaactatc
aactcccttgtgatcgctgcaattattgtgacccggaagctgcaccatccagccaattat
ttaatttgttcccttgcagtcacagattttcttgtggctgtcctggtgatgcccttcagc
attgtgtatattgtgagagagagctggattatggggcaagtggtctgtgacatttggctg
agtgttgacattacctgctgcacgtgctccatcttgcatctctcagctatagctttggat
cggtatcgagcaatcacagatgctgttgagtatgccaggaaaaggactccaaagcatgct
ggcattatgattacaatagtttggattatatctgtttttatctctatgcctcctctattc
tggaggcaccaaggaactagcagagatgatgaatgcatcatcaagcacgaccacattgtt
tccaccatttactcaacatttggagctttctacatcccactggcattgattttgatcctt
tactacaaaatatatagagcagcaaagacattataccacaagagacaagcaagtaggatt
gcaaaggaggaggtgaatggccaagtccttttggagagtggtgagaaaagcactaaatca
gtttccacatcctatgtactagaaaagtctttatctgacccatcaacagactttgataaa
attcatagcacagtgagaagtctcaggtctgaattcaagcatgagaaatcttggagaagg
caaaagatctcaggtacaagagaacggaaagcagccactaccctgggattaatcttgggt
gcatttgtaatatgttggcttcctttttttgtaaaagaattagttgttaatgtctgtgac
aaatgtaaaatttctgaagaaatgtccaattttttggcatggcttgggtatctcaattcc
cttataaatccactgatttacacaatctttaatgaagacttcaagaaagcattccaaaag
cttgtgcgatgtcgatgttag

KEGG   Homo sapiens (human): 338442Help
Entry
338442            CDS       T01001                                 

Gene name
HCAR2, GPR109A, HCA2, HM74a, HM74b, NIACR1, PUMAG, Puma-g
Definition
(RefSeq) hydroxycarboxylic acid receptor 2
  KO
K08402  hydroxycarboxylic acid receptor 2/3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    338442 (HCAR2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    338442 (HCAR2)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Others
   Hydroxy-carboxylic acid
    338442 (HCAR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1
Motif
Other DBs
NCBI-GeneID: 338442
NCBI-ProteinID: NP_808219
OMIM: 609163
HGNC: 24827
Ensembl: ENSG00000182782
Vega: OTTHUMG00000162722
Pharos: Q8TDS4(Tclin)
UniProt: Q8TDS4
LinkDB All DBs
Position
12q24.31
AA seq 363 aa AA seqDB search
MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK
SSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTV
VAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSF
SICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF
VICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS
FPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGP
TSP
NT seq 1092 nt NT seq  +upstreamnt  +downstreamnt
atgaatcggcaccatctgcaggatcactttctggaaatagacaagaagaactgctgtgtg
ttccgagatgacttcattgtcaaggtgttgccgccggtgttggggctggagtttatcttc
gggcttctgggcaatggccttgccctgtggattttctgtttccacctcaagtcctggaaa
tccagccggattttcctgttcaacctggcagtggctgactttctactgatcatctgcctg
cccttcctgatggacaactatgtgaggcgttgggactggaagtttggggacatcccttgc
cggctgatgctcttcatgttggctatgaaccgccagggcagcatcatcttcctcacggtg
gtggcggtagacaggtatttccgggtggtccatccccaccacgccctgaacaagatctcc
aatcggacagcagccatcatctcttgccttctgtggggcatcactattggcctgacagtc
cacctcctgaagaagaagatgccgatccagaatggcggtgcaaatttgtgcagcagcttc
agcatctgccataccttccagtggcacgaagccatgttcctcctggagttcttcctgccc
ctgggcatcatcctgttctgctcagccagaattatctggagcctgcggcagagacaaatg
gaccggcatgccaagatcaagagagccatcaccttcatcatggtggtggccatcgtcttt
gtcatctgcttccttcccagcgtggttgtgcggatccgcatcttctggctcctgcacact
tcgggcacgcagaattgtgaagtgtaccgctcggtggacctggcgttctttatcactctc
agcttcacctacatgaacagcatgctggaccccgtggtgtactacttctccagcccatcc
tttcccaacttcttctccactttgatcaaccgctgcctccagaggaagatgacaggtgag
ccagataataaccgcagcacgagcgtcgagctcacaggggaccccaacaaaaccagaggc
gctccagaggcgttaatggccaactccggtgagccatggagcccctcttatctgggccca
acctctccttaa

KEGG   Homo sapiens (human): 4886Help
Entry
4886              CDS       T01001                                 

Gene name
NPY1R, NPY1-R, NPYR
Definition
(RefSeq) neuropeptide Y receptor Y1
  KO
K04204  neuropeptide Y receptor type 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04923  Regulation of lipolysis in adipocytes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    4886 (NPY1R)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    4886 (NPY1R)
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    4886 (NPY1R)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    4886 (NPY1R)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Neuropeptide Y
    4886 (NPY1R)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx Git3 Gaa1
Motif
Other DBs
NCBI-GeneID: 4886
NCBI-ProteinID: NP_000900
OMIM: 162641
HGNC: 7956
Ensembl: ENSG00000164128
Vega: OTTHUMG00000161371
Pharos: P25929(Tchem)
UniProt: P25929
LinkDB All DBs
Position
4q32.2
AA seq 384 aa AA seqDB search
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
NT seq 1155 nt NT seq  +upstreamnt  +downstreamnt
atgaattcaacattattttcccaggttgaaaatcattcagtccactctaatttctcagag
aagaatgcccagcttctggcttttgaaaatgatgattgtcatctgcccttggccatgata
tttaccttagctcttgcttatggagctgtgatcattcttggtgtctctggaaacctggcc
ttgatcataatcatcttgaaacaaaaggagatgagaaatgttaccaacatcctgattgtg
aacctttccttctcagacttgcttgttgccatcatgtgtctcccctttacatttgtctac
acattaatggaccactgggtctttggtgaggcgatgtgtaagttgaatccttttgtgcaa
tgtgtttcaatcactgtgtccattttctctctggttctcattgctgtggaacgacatcag
ctgataatcaaccctcgagggtggagaccaaataatagacatgcttatgtaggtattgct
gtgatttgggtccttgctgtggcttcttctttgcctttcctgatctaccaagtaatgact
gatgagccgttccaaaatgtaacacttgatgcgtacaaagacaaatacgtgtgctttgat
caatttccatcggactctcataggttgtcttataccactctcctcttggtgctgcagtat
tttggtccactttgttttatatttatttgctacttcaagatatatatacgcctaaaaagg
agaaacaacatgatggacaagatgagagacaataagtacaggtccagtgaaaccaaaaga
atcaatatcatgctgctctccattgtggtagcatttgcagtctgctggctccctcttacc
atctttaacactgtgtttgattggaatcatcagatcattgctacctgcaaccacaatctg
ttattcctgctctgccacctcacagcaatgatatccacttgtgtcaaccccatattttat
gggttcctgaacaaaaacttccagagagacttgcagttcttcttcaacttttgtgatttc
cggtctcgggatgatgattatgaaacaatagccatgtccacgatgcacacagatgtttcc
aaaacttctttgaagcaagcaagcccagtcgcatttaaaaaaatcaacaacaatgatgat
aatgaaaaaatctga

KEGG   Homo sapiens (human): 5021Help
Entry
5021              CDS       T01001                                 

Gene name
OXTR, OT-R
Definition
(RefSeq) oxytocin receptor
  KO
K04229  oxytocin receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04921  Oxytocin signaling pathway
Drug target
Atosiban (DG02835): D03008 D07475
Carbetocin: D07229
Cargutocin: D09797
Demoxytocin: D07228
Epelsiban (DG01543): D10117 D10118
Oxytocin: D00089
Retosiban: D08986
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    5021 (OXTR)
   04024 cAMP signaling pathway
    5021 (OXTR)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5021 (OXTR)
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    5021 (OXTR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    5021 (OXTR)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Oxytocin
    5021 (OXTR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srv 7tm_4 7TM_GPCR_Srsx
Motif
Other DBs
NCBI-GeneID: 5021
NCBI-ProteinID: NP_000907
OMIM: 167055
HGNC: 8529
Ensembl: ENSG00000180914
Vega: OTTHUMG00000090537
Pharos: P30559(Tclin)
UniProt: P30559 B2R9L7
LinkDB All DBs
Position
3p25.3
AA seq 389 aa AA seqDB search
MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
SASKKSNSSSFVLSHRSSSQRSCSQPSTA
NT seq 1170 nt NT seq  +upstreamnt  +downstreamnt
atggagggcgcgctcgcagccaactggagcgccgaggcagccaacgccagcgccgcgccg
ccgggggccgagggcaaccgcaccgccggacccccgcggcgcaacgaggccctggcgcgc
gtggaggtggcggtgctgtgtctcatcctgctcctggcgctgagcgggaacgcgtgtgtg
ctgctggcgctgcgcaccacacgccagaagcactcgcgcctcttcttcttcatgaagcac
ctaagcatcgccgacctggtggtggcagtgtttcaggtgctgccgcagttgctgtgggac
atcaccttccgcttctacgggcccgacctgctgtgccgcctggtcaagtacttgcaggtg
gtgggcatgttcgcctccacctacctgctgctgctcatgtccctggaccgctgcctggcc
atctgccagccgctgcgctcgctgcgccgccgcaccgaccgcctggcagtgctcgccacg
tggctcggctgcctggtggccagcgcgccgcaggtgcacatcttctctctgcgcgaggtg
gctgacggcgtcttcgactgctgggccgtcttcatccagccctggggacccaaggcctac
atcacatggatcacgctagctgtctacatcgtgccggtcatcgtgctcgctgcctgctac
ggccttatcagcttcaagatctggcagaacttgcggctcaagaccgctgcagcggcggcg
gccgaggcgccagagggcgcggcggctggcgatggggggcgcgtggccctggcgcgtgtc
agcagcgtcaagctcatctccaaggccaagatccgcacggtcaagatgactttcatcatc
gtgctggccttcatcgtgtgctggacgcctttcttcttcgtgcagatgtggagcgtctgg
gatgccaacgcgcccaaggaagcctcggccttcatcatcgtcatgctcctggccagcctc
aacagctgctgcaacccctggatctacatgctgttcacgggccacctcttccacgaactc
gtgcagcgcttcctgtgctgctccgccagctacctgaagggcagacgcctgggagagacg
agtgccagcaaaaagagcaactcgtcctcctttgtcctgagccatcgcagctccagccag
aggagctgctcccagccatccacggcgtga

KEGG   Homo sapiens (human): 56670Help
Entry
56670             CDS       T01001                                 

Gene name
SUCNR1, GPR91
Definition
(RefSeq) succinate receptor 1
  KO
K10042  succinate receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    56670 (SUCNR1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    56670 (SUCNR1)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Base and nucleoside
   Purine / pyrimidine
    56670 (SUCNR1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1
Motif
Other DBs
NCBI-GeneID: 56670
NCBI-ProteinID: NP_149039
OMIM: 606381
HGNC: 4542
Ensembl: ENSG00000198829
Vega: OTTHUMG00000159880
Pharos: Q9BXA5(Tbio)
UniProt: Q9BXA5
LinkDB All DBs
Position
3q25.1
AA seq 334 aa AA seqDB search
MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNI
YLFNLSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDR
YLIIKYPFREHLLQKKEFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGD
PNYNLIYSMCLTLLGFLIPLFVMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVI
FSVLFTPYHVMRNVRIASRLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGD
HFRDMLMNQLRHNFKSLTSFSRWAHELLLSFREK
NT seq 1005 nt NT seq  +upstreamnt  +downstreamnt
atgctggggatcatggcatggaatgcaacttgcaaaaactggctggcagcagaggctgcc
ctggaaaagtactacctttccattttttatgggattgagttcgttgtgggagtccttgga
aataccattgttgtttacggctacatcttctctctgaagaactggaacagcagtaatatt
tatctctttaacctctctgtctctgacttagcttttctgtgcaccctccccatgctgata
aggagttatgccaatggaaactggatatatggagacgtgctctgcataagcaaccgatat
gtgcttcatgccaacctctataccagcattctctttctcacttttatcagcatagatcga
tacttgataattaagtatcctttccgagaacaccttctgcaaaagaaagagtttgctatt
ttaatctccttggccatttgggttttagtaaccttagagttactacccatacttcccctt
ataaatcctgttataactgacaatggcaccacctgtaatgattttgcaagttctggagac
cccaactacaacctcatttacagcatgtgtctaacactgttggggttccttattcctctt
tttgtgatgtgtttcttttattacaagattgctctcttcctaaagcagaggaataggcag
gttgctactgctctgccccttgaaaagcctctcaacttggtcatcatggcagtggtaatc
ttctctgtgctttttacaccctatcacgtcatgcggaatgtgaggatcgcttcacgcctg
gggagttggaagcagtatcagtgcactcaggtcgtcatcaactccttttacattgtgaca
cggcctttggcctttctgaacagtgtcatcaaccctgtcttctattttcttttgggagat
cacttcagggacatgctgatgaatcaactgagacacaacttcaaatcccttacatccttt
agcagatgggctcatgaactcctactttcattcagagaaaagtga

KEGG   Homo sapiens (human): 5733Help
Entry
5733              CDS       T01001                                 

Gene name
PTGER3, EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3-VI, EP3e, PGE2-R
Definition
(RefSeq) prostaglandin E receptor 3
  KO
K04260  prostaglandin E receptor 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04923  Regulation of lipolysis in adipocytes
hsa05163  Human cytomegalovirus infection
hsa05200  Pathways in cancer
Drug target
Enprostil: D01891
Misoprostol: D00419
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    5733 (PTGER3)
   04024 cAMP signaling pathway
    5733 (PTGER3)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5733 (PTGER3)
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    5733 (PTGER3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    5733 (PTGER3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    5733 (PTGER3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    5733 (PTGER3)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Lipid
   Prostaglandin
    5733 (PTGER3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srx 7TM_GPCR_Srbc
Motif
Other DBs
NCBI-GeneID: 5733
NCBI-ProteinID: NP_001119516
OMIM: 176806
HGNC: 9595
Ensembl: ENSG00000050628
Vega: OTTHUMG00000009399
Pharos: P43115(Tclin)
UniProt: P43115
LinkDB All DBs
Position
1p31.1
AA seq 390 aa AA seqDB search
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
RYHTNNYASSSTSLPCQCSSTLMWSDHLER
NT seq 1173 nt NT seq  +upstreamnt  +downstreamnt
atgaaggagacccggggctacggaggggatgcccccttctgcacccgcctcaaccactcc
tacacaggcatgtgggcgcccgagcgttccgccgaggcgcggggcaacctcacgcgccct
ccagggtctggcgaggattgcggatcggtgtccgtggccttcccgatcaccatgctgctc
actggtttcgtgggcaacgcactggccatgctgctcgtgtcgcgcagctaccggcgccgg
gagagcaagcgcaagaagtccttcctgctgtgcatcggctggctggcgctcaccgacctg
gtcgggcagcttctcaccaccccggtcgtcatcgtcgtgtacctgtccaagcagcgttgg
gagcacatcgacccgtcggggcggctctgcacctttttcgggctgaccatgactgttttc
gggctctcctcgttgttcatcgccagcgccatggccgtcgagcgggcgctggccatcagg
gcgccgcactggtatgcgagccacatgaagacgcgtgccacccgcgctgtgctgctcggc
gtgtggctggccgtgctcgccttcgccctgctgccggtgctgggcgtgggccagtacacc
gtccagtggcccgggacgtggtgcttcatcagcaccgggcgagggggcaacgggactagc
tcttcgcataactggggcaaccttttcttcgcctctgcctttgccttcctggggctcttg
gcgctgacagtcaccttttcctgcaacctggccaccattaaggccctggtgtcccgctgc
cgggccaaggccacggcatctcagtccagtgcccagtggggccgcatcacgaccgagacg
gccattcagcttatggggatcatgtgcgtgctgtcggtctgctggtctccgctcctgata
atgatgttgaaaatgatcttcaatcagacatcagttgagcactgcaagacacacacggag
aagcagaaagaatgcaacttcttcttaatagctgttcgcctggcttcactgaaccagatc
ttggatccttgggtttacctgctgttaagaaagatccttcttcgaaagttttgccagatc
aggtaccacacaaacaactatgcatccagctccacctccttaccctgccagtgttcctca
accttgatgtggagcgaccatttggaaagatga

KEGG   Homo sapiens (human): 6751Help
Entry
6751              CDS       T01001                                 

Gene name
SSTR1, SRIF-2, SS-1-R, SS1-R, SS1R
Definition
(RefSeq) somatostatin receptor 1
  KO
K04217  somatostatin receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04935  Growth hormone synthesis, secretion and action
Drug target
Pasireotide (DG00503): D10147 D10497 D10566
Seglitide acetate: D05812
Somatostatin: D07431
Veldoreotide: D11192
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    6751 (SSTR1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    6751 (SSTR1)
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    6751 (SSTR1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    6751 (SSTR1)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Somatostatin
    6751 (SSTR1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv 7tm_4 T2SSM Piezo_RRas_bdg
Motif
Other DBs
NCBI-GeneID: 6751
NCBI-ProteinID: NP_001040
OMIM: 182451
HGNC: 11330
Ensembl: ENSG00000139874
Vega: OTTHUMG00000140249
Pharos: P30872(Tclin)
UniProt: P30872 Q86SW9
LinkDB All DBs
Position
14q21.1
AA seq 391 aa AA seqDB search
MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAIL
ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL
RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG
VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC
LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD
DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS
RAYSVEDFQPENLESGGVFRNGTCTSRITTL
NT seq 1176 nt NT seq  +upstreamnt  +downstreamnt
atgttccccaatggcaccgcctcctctccttcctcctctcctagccccagcccgggcagc
tgcggcgaaggcggcggcagcaggggccccggggccggcgctgcggacggcatggaggag
ccagggcgaaatgcgtcccagaacgggaccttgagcgagggccagggcagcgccatcctg
atctctttcatctactccgtggtgtgcctggtggggctgtgtgggaactctatggtcatc
tacgtgatcctgcgctatgccaagatgaagacggccaccaacatctacatcctaaatctg
gccattgctgatgagctgctcatgctcagcgtgcccttcctagtcacctccacgttgttg
cgccactggcccttcggtgcgctgctctgccgcctcgtgctcagcgtggacgcggtcaac
atgttcaccagcatctactgtctgactgtgctcagcgtggaccgctacgtggccgtggtg
catcccatcaaggcggcccgctaccgccggcccaccgtggccaaggtagtaaacctgggc
gtgtgggtgctatcgctgctcgtcatcctgcccatcgtggtcttctctcgcaccgcggcc
aacagcgacggcacggtggcttgcaacatgctcatgccagagcccgctcaacgctggctg
gtgggcttcgtgttgtacacatttctcatgggcttcctgctgcccgtgggggctatctgc
ctgtgctacgtgctcatcattgctaagatgcgcatggtggccctcaaggccggctggcag
cagcgcaagcgctcggagcgcaagatcaccttaatggtgatgatggtggtgatggtgttt
gtcatctgctggatgcctttctacgtggtgcagctggtcaacgtgtttgctgagcaggac
gacgccacggtgagtcagctgtcggtcatcctcggctatgccaacagctgcgccaacccc
atcctctatggctttctctcagacaacttcaagcgctctttccaacgcatcctatgcctc
agctggatggacaacgccgcggaggagccggttgactattacgccaccgcgctcaagagc
cgtgcctacagtgtggaagacttccaacctgagaacctggagtccggcggcgtcttccgt
aatggcacctgcacgtcccggatcacgacgctctga

KEGG   Homo sapiens (human): 6752Help
Entry
6752              CDS       T01001                                 

Gene name
SSTR2
Definition
(RefSeq) somatostatin receptor 2
  KO
K04218  somatostatin receptor 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04935  Growth hormone synthesis, secretion and action
hsa04971  Gastric acid secretion
Drug target
Indium (111In) pentetreotide: D02108
Lanreotide: D04666
Lutetium (177Lu) oxodotreotide: D11033
Octreotide (DG00501): D00442 D02250 D05230 D06495 D11204
Pasireotide (DG00503): D10147 D10497 D10566
Seglitide acetate: D05812
Somatostatin: D07431
Vapreotide (DG00502): D06281 D09988
Veldoreotide: D11192
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    6752 (SSTR2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    6752 (SSTR2)
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    6752 (SSTR2)
  09154 Digestive system
   04971 Gastric acid secretion
    6752 (SSTR2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    6752 (SSTR2)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Somatostatin
    6752 (SSTR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv FtsK_4TM
Motif
Other DBs
NCBI-GeneID: 6752
NCBI-ProteinID: NP_001041
OMIM: 182452
HGNC: 11331
Ensembl: ENSG00000180616
Vega: OTTHUMG00000178343
Pharos: P30874(Tclin)
UniProt: P30874
LinkDB All DBs
Position
17q25.1
AA seq 369 aa AA seqDB search
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG
NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT
VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY
AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI
RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL
TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL
LNGDLQTSI
NT seq 1110 nt NT seq  +upstreamnt  +downstreamnt
atggacatggcggatgagccactcaatggaagccacacatggctatccattccatttgac
ctcaatggctctgtggtgtcaaccaacacctcaaaccagacagagccgtactatgacctg
acaagcaatgcagtcctcacattcatctattttgtggtctgcatcattgggttgtgtggc
aacacacttgtcatttatgtcatcctccgctatgccaagatgaagaccatcaccaacatt
tacatcctcaacctggccatcgcagatgagctcttcatgctgggtctgcctttcttggct
atgcaggtggctctggtccactggccctttggcaaggccatttgccgggtggtcatgact
gtggatggcatcaatcagttcaccagcatcttctgcctgacagtcatgagcatcgaccga
tacctggctgtggtccaccccatcaagtcggccaagtggaggagaccccggacggccaag
atgatcaccatggctgtgtggggagtctctctgctggtcatcttgcccatcatgatatat
gctgggctccggagcaaccagtgggggagaagcagctgcaccatcaactggccaggtgaa
tctggggcttggtacacagggttcatcatctacactttcattctggggttcctggtaccc
ctcaccatcatctgtctttgctacctgttcattatcatcaaggtgaagtcctctggaatc
cgagtgggctcctctaagaggaagaagtctgagaagaaggtcacccgaatggtgtccatc
gtggtggctgtcttcatcttctgctggcttcccttctacatattcaacgtttcttccgtc
tccatggccatcagccccaccccagcccttaaaggcatgtttgactttgtggtggtcctc
acctatgctaacagctgtgccaaccctatcctatatgccttcttgtctgacaacttcaag
aagagcttccagaatgtcctctgcttggtcaaggtgagcggcacagatgatggggagcgg
agtgacagtaagcaggacaaatcccggctgaatgagaccacggagacccagaggaccctc
ctcaatggagacctccaaaccagtatctga

KEGG   Homo sapiens (human): 6755Help
Entry
6755              CDS       T01001                                 

Gene name
SSTR5, SS-5-R
Definition
(RefSeq) somatostatin receptor 5
  KO
K04221  somatostatin receptor 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04935  Growth hormone synthesis, secretion and action
Drug target
Indium (111In) pentetreotide: D02108
Lanreotide: D04666
Pasireotide (DG00503): D10147 D10497 D10566
Seglitide acetate: D05812
Somatostatin: D07431
Vapreotide (DG00502): D06281 D09988
Veldoreotide: D11192
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    6755 (SSTR5)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    6755 (SSTR5)
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    6755 (SSTR5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    6755 (SSTR5)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Somatostatin
    6755 (SSTR5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv 7TM_GPCR_Srw
Motif
Other DBs
NCBI-GeneID: 6755
NCBI-ProteinID: NP_001044
OMIM: 182455
HGNC: 11334
Ensembl: ENSG00000162009
Vega: OTTHUMG00000047842
Pharos: P35346(Tclin)
UniProt: P35346
LinkDB All DBs
Position
16p13.3
AA seq 364 aa AA seqDB search
MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL
VIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDG
VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV
QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR
RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCAN
PVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQ
TSKL
NT seq 1095 nt NT seq  +upstreamnt  +downstreamnt
atggagcccctgttcccagcctccacgcccagctggaacgcctcctccccgggggctgcc
tctggaggcggtgacaacaggacgctggtggggccggcgccctcggcaggggcccgggcg
gtgctggtgcccgtgctgtacctgctggtgtgtgcggccgggctgggcgggaacacgctg
gtcatctacgtggtgctgcgcttcgccaagatgaagaccgtcaccaacatctacattctc
aacctggcagtggccgacgtcctgtacatgctggggctgcctttcctggccacgcagaac
gccgcgtccttctggcccttcggccccgtcctgtgccgcctggtcatgacgctggacggc
gtcaaccagttcaccagtgtcttctgcctgacagtcatgagcgtggaccgctacctggca
gtggtgcacccgctgagctcggcccgctggcgccgcccgcgtgtggccaagctggcgagc
gccgcggcctgggtcctgtctctgtgcatgtcgctgccgctcctggtgttcgcggacgtg
caggagggcggtacctgcaacgccagctggccggagcccgtggggctgtggggcgccgtc
ttcatcatctacacggccgtgctgggcttcttcgcgccgctgctggtcatctgcctgtgc
tacctgctcatcgtggtgaaggtgagggcggcgggcgtgcgcgtgggctgcgtgcggcgg
cgctcggagcggaaggtgacgcgcatggtgttggtggtggtgctggtgtttgcgggatgt
tggctgcccttcttcaccgtcaacatcgtcaacctggccgtggcgctgccccaggagccc
gcctccgccggcctctacttcttcgtggtcatcctctcctacgccaacagctgtgccaac
cccgtcctctacggcttcctctctgacaacttccgccagagcttccagaaggttctgtgc
ctccgcaagggctctggtgccaaggacgctgacgccacggagccgcgtccagacaggatc
cggcagcagcaggaggccacgccacccgcgcaccgcgccgcagccaacgggcttatgcag
accagcaagctgtga

KEGG   Homo sapiens (human): 8843Help
Entry
8843              CDS       T01001                                 

Gene name
HCAR3, GPR109B, HCA3, HM74, PUMAG, Puma-g
Definition
(RefSeq) hydroxycarboxylic acid receptor 3
  KO
K08402  hydroxycarboxylic acid receptor 2/3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    8843 (HCAR3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    8843 (HCAR3)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Others
   Hydroxy-carboxylic acid
    8843 (HCAR3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1
Motif
Other DBs
NCBI-GeneID: 8843
NCBI-ProteinID: NP_006009
OMIM: 606039
HGNC: 16824
Ensembl: ENSG00000255398
Vega: OTTHUMG00000166034
Pharos: P49019(Tbio)
UniProt: P49019
LinkDB All DBs
Position
12q24.31
AA seq 387 aa AA seqDB search
MNRHHLQDHFLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK
SSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTV
VAVDRYFRVVHPHHALNKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISF
SICHTFRWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF
VICFLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS
FPNFFSTLINRCLQRKITGEPDNNRSTSVELTGDPNKTRGAPEALIANSGEPWSPSYLGP
TSNNHSKKGHCHQEPASLEKQLGCCIE
NT seq 1164 nt NT seq  +upstreamnt  +downstreamnt
atgaatcggcaccatctgcaggatcactttctggaaatagacaagaagaactgctgtgtg
ttccgagatgacttcattgccaaggtgttgccgccggtgttggggctggagtttatcttt
gggcttctgggcaatggccttgccctgtggattttctgtttccacctcaagtcctggaaa
tccagccggattttcctgttcaacctggcagtagctgactttctactgatcatctgcctg
ccgttcgtgatggactactatgtgcggcgttcagactggaagtttggggacatcccttgc
cggctggtgctcttcatgtttgccatgaaccgccagggcagcatcatattcctcacggtg
gtggcggtagacaggtatttccgggtggtccatccccaccacgccctgaacaagatctcc
aattggacagcagccatcatctcttgccttctgtggggcatcactgttggcctaacagtc
cacctcctgaagaagaagttgctgatccagaatggcactgcaaatgtgtgcatcagcttc
agcatctgccataccttccggtggcacgaagctatgttcctcctggagttcttcctgccc
ctgggcatcatcctgttctgctcagccagaattatctggagcctgcggcagagacaaatg
gaccggcatgccaagatcaagagagccatcaccttcatcatggtggtggccatcgtcttt
gtcatctgcttccttcccagcgtggttgtgcggatccacatcttctggctcctgcacact
tcgggcacgcagaattgtgaagtgtaccgctcggtggacctggcgttctttatcactctc
agcttcacctacatgaacagcatgctggaccccgtggtgtactacttctccagcccatcc
tttcccaacttcttctccactttgatcaaccgctgcctccagaggaagataacaggtgag
ccagataataaccgcagcacgagcgtcgagctcacaggggaccccaacaaaaccagaggc
gctccagaggcgttaatcgccaactccggtgagccatggagcccctcttatctgggccca
acctcaaataaccattccaagaagggacattgtcaccaagaaccagcatctctggagaaa
cagttgggctgttgcatcgagtaa

KEGG   Homo sapiens (human): 9568Help
Entry
9568              CDS       T01001                                 

Gene name
GABBR2, EIEE59, GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099, NDPLHS
Definition
(RefSeq) gamma-aminobutyric acid type B receptor subunit 2
  KO
K04615  gamma-aminobutyric acid type B receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse
hsa04742  Taste transduction
hsa04915  Estrogen signaling pathway
hsa04929  GnRH secretion
hsa05032  Morphine addiction
Drug target
Aminobutyric acid: D00058
Arbaclofen (DG01354): D08861 D09791
Baclofen: D00241
Progabide: D05621
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    9568 (GABBR2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    9568 (GABBR2)
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    9568 (GABBR2)
   04915 Estrogen signaling pathway
    9568 (GABBR2)
  09156 Nervous system
   04727 GABAergic synapse
    9568 (GABBR2)
  09157 Sensory system
   04742 Taste transduction
    9568 (GABBR2)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    9568 (GABBR2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    9568 (GABBR2)
G protein-coupled receptors [BR:hsa04030]
 Metabotropic glutamate receptor family
  GABA
   9568 (GABBR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_3 ANF_receptor GBR2_CC Peripla_BP_6 Cation_ATPase_C UPF0242 GAPT HOOK
Motif
Other DBs
NCBI-GeneID: 9568
NCBI-ProteinID: NP_005449
OMIM: 607340
HGNC: 4507
Ensembl: ENSG00000136928
Vega: OTTHUMG00000020345
Pharos: O75899(Tclin)
UniProt: O75899 H9NIL8
LinkDB All DBs
Structure
PDB: 

Position
9q22.33
AA seq 941 aa AA seqDB search
MASPRSSGQPGPPPPPPPPPARLLLLLLLPLLLPLAPGAWGWARGAPRPPPSSPPLSIMG
LMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDA
IKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDN
AVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSV
KKLKGNDVRIILGQFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSWWEQVHTEANSS
RCLRKNLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHGYAYD
GIWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTGQVVFRNG
ERMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLP
LYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLD
GSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVI
VGGMLLIDLCILICWQAVDPLRRTVEKYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIV
YAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQ
FCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSV
NQASTSRLEGLQSENHRLRMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILNL
GNFTESTDGGKAILKNHLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILH
HAYLPSIGGVDASCVSPCVSPTASPRHRHVPPSFRVMVSGL
NT seq 2826 nt NT seq  +upstreamnt  +downstreamnt
atggcttccccgcggagctccgggcagcccgggccgccgccgccgccgccaccgccgccc
gcgcgcctgctactgctactgctgctgccgctgctgctgcctctggcgcccggggcctgg
ggctgggcgcggggcgccccccggccgccgcccagcagcccgccgctctccatcatgggc
ctcatgccgctcaccaaggaggtggccaagggcagcatcgggcgcggtgtgctccccgcc
gtggaactggccatcgagcagatccgcaacgagtcactcctgcgcccctacttcctcgac
ctgcggctctatgacacggagtgcgacaacgcaaaagggttgaaagccttctacgatgca
ataaaatacgggcctaaccacttgatggtgtttggaggcgtctgtccatccgtcacatcc
atcattgcagagtccctccaaggctggaatctggtgcagctttcttttgctgcaaccacg
cctgttctagccgataagaaaaaatacccttatttctttcggaccgtcccatcagacaat
gcggtgaatccagccattctgaagttgctcaagcactaccagtggaagcgcgtgggcacg
ctgacgcaagacgttcagaggttctctgaggtgcggaatgacctgactggagttctgtat
ggcgaggacattgagatttcagacaccgagagcttctccaacgatccctgtaccagtgtc
aaaaagctgaaggggaatgatgtgcggatcatccttggccagtttgaccagaatatggca
gcaaaagtgttctgttgtgcatacgaggagaacatgtatggtagtaaatatcagtggatc
attccgggctggtacgagccttcttggtgggagcaggtgcacacggaagccaactcatcc
cgctgcctccggaagaatctgcttgctgccatggagggctacattggcgtggatttcgag
cccctgagctccaagcagatcaagaccatctcaggaaagactccacagcagtatgagaga
gagtacaacaacaagcggtcaggcgtggggcccagcaagttccacgggtacgcctacgat
ggcatctgggtcatcgccaagacactgcagagggccatggagacactgcatgccagcagc
cggcaccagcggatccaggacttcaactacacggaccacacgctgggcaggatcatcctc
aatgccatgaacgagaccaacttcttcggggtcacgggtcaagttgtattccggaatggg
gagagaatggggaccattaaatttactcaatttcaagacagcagggaggtgaaggtggga
gagtacaacgctgtggccgacacactggagatcatcaatgacaccatcaggttccaagga
tccgaaccaccaaaagacaagaccatcatcctggagcagctgcggaagatctccctacct
ctctacagcatcctctctgccctcaccatcctcgggatgatcatggccagtgcttttctc
ttcttcaacatcaagaaccggaatcagaagctcataaagatgtcgagtccatacatgaac
aaccttatcatccttggagggatgctctcctatgcttccatatttctctttggccttgat
ggatcctttgtctctgaaaagacctttgaaacactttgcaccgtcaggacctggattctc
accgtgggctacacgaccgcttttggggccatgtttgcaaagacctggagagtccacgcc
atcttcaaaaatgtgaaaatgaagaagaagatcatcaaggaccagaaactgcttgtgatc
gtggggggcatgctgctgatcgacctgtgtatcctgatctgctggcaggctgtggacccc
ctgcgaaggacagtggagaagtacagcatggagccggacccagcaggacgggatatctcc
atccgccctctcctggagcactgtgagaacacccatatgaccatctggcttggcatcgtc
tatgcctacaagggacttctcatgttgttcggttgtttcttagcttgggagacccgcaac
gtcagcatccccgcactcaacgacagcaagtacatcgggatgagtgtctacaacgtgggg
atcatgtgcatcatcggggccgctgtctccttcctgacccgggaccagcccaatgtgcag
ttctgcatcgtggctctggtcatcatcttctgcagcaccatcaccctctgcctggtattc
gtgccgaagctcatcaccctgagaacaaacccagatgcagcaacgcagaacaggcgattc
cagttcactcagaatcagaagaaagaagattctaaaacgtccacctcggtcaccagtgtg
aaccaagccagcacatcccgcctggagggcctacagtcagaaaaccatcgcctgcgaatg
aagatcacagagctggataaagacttggaagaggtcaccatgcagctgcaggacacacca
gaaaagaccacctacattaaacagaaccactaccaagagctcaatgacatcctcaacctg
ggaaacttcactgagagcacagatggaggaaaggccattttaaaaaatcacctcgatcaa
aatccccagctacagtggaacacaacagagccctctcgaacatgcaaagatcctatagaa
gatataaactctccagaacacatccagcgtcggctgtccctccagctccccatcctccac
cacgcctacctcccatccatcggaggcgtggacgccagctgtgtcagcccctgcgtcagc
cccaccgccagcccccgccacagacatgtgccaccctccttccgagtcatggtctcgggc
ctgtaa

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