KEGG   Homo sapiens (human): 115653
Entry
115653            CDS       T01001                                 

Gene name
KIR3DL3, CD158Z, KIR3DL7, KIR44, KIRC1
Definition
(RefSeq) killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
  KO
K07980  killer cell immunoglobulin-like receptor 3DL
Organism
hsa  Homo sapiens (human)
Pathway
hsa04612  Antigen processing and presentation
hsa04650  Natural killer cell mediated cytotoxicity
hsa05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    115653 (KIR3DL3)
   04612 Antigen processing and presentation
    115653 (KIR3DL3)
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    115653 (KIR3DL3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    115653 (KIR3DL3)
CD molecules [BR:hsa04090]
 Proteins
  115653 (KIR3DL3)
SSDB
Motif
Pfam: ig Ig_2 Ig_3
Other DBs
NCBI-GeneID: 115653
NCBI-ProteinID: NP_703144
OMIM: 610095
HGNC: 16312
Ensembl: ENSG00000242019
Vega: OTTHUMG00000065884
UniProt: A0A0B4J1R5
LinkDB
Position
19q13.42
AA seq 410 aa
MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL
SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV
HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY
SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENV
TLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRAL
PHAWSDPSDPLPVSVTGNSRNLHVLIGTSVVIIPFAILLFFLLHRWCANKKNAVVMDQEP
AGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTSV
NT seq 1233 nt   +upstreamnt  +downstreamnt
atgtcgctcatggtcgtcagcatggcgtgtgttgggttcttcttgctggaggggccctgg
ccacatgtgggtggtcaggacaagcccttcctctctgcctggcccggcactgtggtgtct
gaaggacaacatgtgactcttcagtgtcgctctcgtcttgggtttaatgaattcagtctg
tccaaagaagacgggatgcctgtccctgagctctacaacagaatattccggaacagcttt
ctcatgggccctgtgaccccagcacatgcagggacctacagatgttgcagttcacaccca
cactcccccactgggtggtcggcacccagcaaccctgtggtgatcatggtcacaggagtc
cacagaaaaccttccctcctggcccacccaggtcccctggtgaaatcaggagagacggtc
atcctgcaatgttggtcagatgtcaggtttgagcgcttccttctgcacagagaggggatc
actgaggaccccttgcgcctcgttggacagctccacgatgcgggttcccaggtcaactat
tccatgggtcccatgacacctgcccttgcagggacctacagatgctttggttctgtcact
cacttaccctatgagttgtcggctcccagtgaccctctggacatcgtggtcgtaggtcta
tatgggaaaccttctctctcagcccagccgggccccacggttcaggcaggagagaatgtg
accttgtcctgcagctcccggagcttgtttgacatttaccatctatccagggaggcggag
gccggtgaacttaggctcactgcagtgctgagggtcaatggaacattccaggccaacttc
cctctgggccctgtgacccacggagggaactacagatgcttcggctctttccgtgccctg
ccccatgcgtggtcagacccgagtgacccactgcccgtttctgtcacaggtaactccaga
aacctgcacgttctgattgggacctcagtggtcatcatcccctttgctatcctcctcttc
tttctccttcatcgctggtgtgccaacaaaaagaatgctgttgtaatggaccaagagcct
gcagggaacagaacagtgaacagggaggactctgatgaacaagaccctcaggaggtgaca
tacgcacagttgaatcactgcgttttcacacagagaaaaatcactcgcccttctcagagg
cccaagacacccccaacagataccagcgtgtaa

KEGG   Homo sapiens (human): 3802
Entry
3802              CDS       T01001                                 

Gene name
KIR2DL1, CD158A, KIR-K64, KIR221, KIR2DL3, NKAT, NKAT-1, NKAT1, p58.1
Definition
(RefSeq) killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
  KO
K07981  killer cell immunoglobulin-like receptor 2DL1/2/3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04612  Antigen processing and presentation
hsa04650  Natural killer cell mediated cytotoxicity
hsa05332  Graft-versus-host disease
Drug target
Lirilumab: D10444
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    3802 (KIR2DL1)
   04612 Antigen processing and presentation
    3802 (KIR2DL1)
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    3802 (KIR2DL1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    3802 (KIR2DL1)
CD molecules [BR:hsa04090]
 Proteins
  3802 (KIR2DL1)
SSDB
Motif
Pfam: ig Ig_3 Ig_2 DUF5589 SIT
Other DBs
NCBI-GeneID: 3802
NCBI-ProteinID: NP_055033
OMIM: 604936
HGNC: 6329
Ensembl: ENSG00000125498
Vega: OTTHUMG00000065885
Pharos: P43626(Tbio)
UniProt: P43626 Q6H2H3 Q6H2H2
LinkDB
Structure
PDB: 
1NKR 1IM9

Position
19q13.42
AA seq 348 aa
MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL
HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI
VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT
FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN
PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV
TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP
NT seq 1047 nt   +upstreamnt  +downstreamnt
atgtcgctcttggtcgtcagcatggcgtgtgttgggttcttcttgctgcagggggcctgg
ccacatgagggagtccacagaaaaccttccctcctggcccacccaggtcgcctggtgaaa
tcagaagagacagtcatcctgcagtgttggtcagatgtcatgtttgaacacttccttctg
cacagagaggggatgtttaacgacactttgcgcctcattggagaacaccatgatggggtc
tccaaggccaacttctccatcagtcgcatgacgcaagacctggcagggacctacagatgc
tacggttctgttactcactccccctatcaggtgtcagctcccagtgaccctctggacatc
gtgatcataggtctatatgagaaaccttctctctcagcccagctgggccccacggttctg
gcaggagagaatgtgaccttgtcctgcagctcccggagctcctatgacatgtaccatcta
tccagggaaggggaggcccatgaacgtaggctccctgcagggcccaaggtcaacggaaca
ttccaggctgactttcctctgggccctgccacccacggagggacctacagatgcttcggc
tctttccatgactctccatacgagtggtcaaagtcaagtgacccactgcttgtttctgtc
acaggaaacccttcaaatagttggccttcacccactgaaccaagctccaaaaccggtaac
ccccgacacctgcacattctgattgggacctcagtggtcatcatcctcttcatcctcctc
ttctttctccttcatcgctggtgctccaacaaaaaaaatgctgcggtaatggaccaagag
tctgcaggaaacagaacagcgaatagcgaggactctgatgaacaagaccctcaggaggtg
acatacacacagttgaatcactgcgttttcacacagagaaaaatcactcgcccttctcag
aggcccaagacacccccaacagatatcatcgtgtacacggaacttccaaatgctgagtcc
agatccaaagttgtctcctgcccatga

KEGG   Homo sapiens (human): 3803
Entry
3803              CDS       T01001                                 

Gene name
KIR2DL2, CD158B1, CD158b, NKAT-6, NKAT6, p58.2
Definition
(RefSeq) killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2
  KO
K07981  killer cell immunoglobulin-like receptor 2DL1/2/3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04612  Antigen processing and presentation
hsa04650  Natural killer cell mediated cytotoxicity
hsa05332  Graft-versus-host disease
Drug target
Lirilumab: D10444
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    3803 (KIR2DL2)
   04612 Antigen processing and presentation
    3803 (KIR2DL2)
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    3803 (KIR2DL2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    3803 (KIR2DL2)
CD molecules [BR:hsa04090]
 Proteins
  3803 (KIR2DL2)
SSDB
Motif
Pfam: ig Ig_3 Ig_2 DUF5589 SIT
Other DBs
NCBI-GeneID: 3803
NCBI-ProteinID: NP_055034
OMIM: 604937
HGNC: 6330
Pharos: P43627(Tdark)
UniProt: P43627 Q6H2H0 Q8N742
LinkDB
Structure
PDB: 
2DLI 1EFX 2DL2

Position
19q13.4
AA seq 348 aa
MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL
HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI
VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT
FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN
PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV
TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP
NT seq 1047 nt   +upstreamnt  +downstreamnt
atgtcgctcatggtcgtcagcatggcgtgtgttgggttcttcttgctgcagggggcctgg
ccacatgagggagtccacagaaaaccttccctcctggcccacccaggtcgcctggtgaaa
tcagaagagacagtcatcctgcaatgttggtcagatgtcaggtttgagcacttccttctg
cacagagaagggaagtttaaggacactttgcacctcattggagagcaccatgatggggtc
tccaaagccaacttctccatcggtcccatgatgcaagaccttgcagggacctacagatgc
tacggttctgttactcactccccctatcagttgtcagctcccagtgaccctctggacatc
gtcatcacaggtctatatgagaaaccttctctctcagcccagccgggccccacggttctg
gcaggagagagcgtgaccttgtcctgcagctcccggagctcctatgacatgtaccatcta
tccagggagggggaggcccatgaatgtaggttctctgcagggcccaaggtcaacggaaca
ttccaggccgactttcctctgggccctgccacccacggaggaacctacagatgcttcggc
tctttccgtgactctccatacgagtggtcaaactcgagtgacccactgcttgtttctgtc
acaggaaacccttcaaatagttggccttcacccactgaaccaagctctaaaaccggtaac
ccccgacacctgcacattctgattgggacctcagtggtcatcatcctcttcatcctcctc
ttctttctccttcatcgctggtgctccaacaaaaaaaatgctgcggtaatggaccaagag
tctgcagggaacagaacagcgaatagcgaggactctgatgaacaagaccctcaggaggtg
acatacacacagttgaatcactgcgttttcacacagagaaaaatcactcgcccttctcag
aggcccaagacacccccaacagatatcatcgtgtacacggaacttccaaatgctgagtcc
agatccaaagttgtctcctgcccatga

KEGG   Homo sapiens (human): 3804
Entry
3804              CDS       T01001                                 

Gene name
KIR2DL3, CD158B2, CD158b, GL183, KIR-023GB, KIR-K7b, KIR-K7c, KIR2DL, KIR2DS5, KIRCL23, NKAT, NKAT2, NKAT2A, NKAT2B, p58
Definition
(RefSeq) killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
  KO
K07981  killer cell immunoglobulin-like receptor 2DL1/2/3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04612  Antigen processing and presentation
hsa04650  Natural killer cell mediated cytotoxicity
hsa05332  Graft-versus-host disease
Drug target
Lirilumab: D10444
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    3804 (KIR2DL3)
   04612 Antigen processing and presentation
    3804 (KIR2DL3)
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    3804 (KIR2DL3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    3804 (KIR2DL3)
CD molecules [BR:hsa04090]
 Proteins
  3804 (KIR2DL3)
SSDB
Motif
Pfam: ig Ig_3 Ig_2 SIT
Other DBs
NCBI-GeneID: 3804
NCBI-ProteinID: NP_056952
OMIM: 604938
HGNC: 6331
Ensembl: ENSG00000243772
Vega: OTTHUMG00000065887
Pharos: P43628(Tbio)
UniProt: P43628 E3NZD8
LinkDB
Structure
PDB: 
1B6U

Position
19q13.42
AA seq 341 aa
MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL
HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI
VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT
FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGN
PRHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQE
VTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP
NT seq 1026 nt   +upstreamnt  +downstreamnt
atgtcgctcatggtcgtcagcatggtgtgtgttgggttcttcttgctgcagggggcctgg
ccacatgagggagtccacagaaaaccttccctcctggcccacccaggtcccctggtgaaa
tcagaagagacagtcatcctgcaatgttggtcagatgtcaggtttcagcacttccttctg
cacagagaagggaagtttaaggacactttgcacctcattggagagcaccatgatggggtc
tccaaggccaacttctccatcggtcccatgatgcaagaccttgcagggacctacagatgc
tacggttctgttactcactccccctatcagttgtcagctcccagtgaccctctggacatc
gtcatcacaggtctatatgagaaaccttctctctcagcccagccgggccccacggttctg
gcaggagagagcgtgaccttgtcctgcagctcccggagctcctatgacatgtaccatcta
tccagggagggggaggcccatgaacgtaggttctctgcagggcccaaggtcaacggaaca
ttccaggccgactttcctctgggccctgccacccacggaggaacctacagatgcttcggc
tctttccgtgactctccatacgagtggtcaaactcgagtgacccactgcttgtttctgtc
acaggaaacccttcaaatagttggccttcacccactgaaccaagctccgaaaccggtaac
cccagacacctgcatgttctgattgggacctcagtggtcatcatcctcttcatcctcctc
ctcttctttctccttcatcgctggtgctgcaacaaaaaaaatgctgttgtaatggaccaa
gagcctgcagggaacagaacagtgaacagggaggactctgatgaacaagaccctcaggag
gtgacatatgcacagttgaatcactgcgttttcacacagagaaaaatcactcgcccttct
cagaggcccaagacacccccaacagatatcatcgtgtacacggaacttccaaatgctgag
ccctga

KEGG   Homo sapiens (human): 3811
Entry
3811              CDS       T01001                                 

Gene name
KIR3DL1, CD158E1, KIR, KIR2DL5B, KIR3DL1/S1, NKAT-3, NKAT3, NKB1, NKB1B
Definition
(RefSeq) killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
  KO
K07980  killer cell immunoglobulin-like receptor 3DL
Organism
hsa  Homo sapiens (human)
Pathway
hsa04612  Antigen processing and presentation
hsa04650  Natural killer cell mediated cytotoxicity
hsa05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    3811 (KIR3DL1)
   04612 Antigen processing and presentation
    3811 (KIR3DL1)
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    3811 (KIR3DL1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    3811 (KIR3DL1)
CD molecules [BR:hsa04090]
 Proteins
  3811 (KIR3DL1)
SSDB
Motif
Pfam: ig Ig_2 Ig_3 SIT MAP17 DUF5589
Other DBs
NCBI-GeneID: 3811
NCBI-ProteinID: NP_001309097
OMIM: 604946
HGNC: 6338
Ensembl: ENSG00000167633
Vega: OTTHUMG00000065933
Pharos: P43629(Tbio)
UniProt: P43629 Q6H2G3 Q8N6C9
LinkDB
Structure
PDB: 

Position
19q13.42
AA seq 444 aa
MLLMVVSMACVGFFLVQRAGPHVGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML
YKEDRIHVPIFHGRLFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN
HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF
SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESV
TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS
PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLL
HLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKT
PPTDTILYTELPNAKPRSKVVSCP
NT seq 1335 nt   +upstreamnt  +downstreamnt
atgttgctcatggtcgtcagcatggcgtgtgttgggttcttcttggtccagagggccggt
ccacacgtgggtggtcaggacaagcccttcctgtctgcctggcccagcgctgtggtgcct
cgaggaggacacgtgactcttcggtgtcactatcgtcataggtttaacaatttcatgcta
tacaaagaagacagaatccacgttcccatcttccatggcagattattccaggagagcttc
aacatgagccctgtgaccacagcacatgcagggaactacacatgtcggggttcacaccca
cactcccccactgggtggtcggcacccagcaaccccgtggtgatcatggtcacaggaaac
cacagaaaaccttccctcctggcccacccaggtcccctggtgaaatcaggagagagagtc
atcctgcaatgttggtcagatatcatgtttgagcacttctttctgcacaaagaggggatc
tctaaggacccctcacgcctcgttggacagatccatgatggggtctccaaggccaatttc
tccatcggtcccatgatgcttgcccttgcagggacctacagatgctacggttctgttact
cacaccccctatcagttgtcagctcccagtgatcccctggacatcgtggtcacaggtcca
tatgagaaaccttctctctcagcccagccgggccccaaggttcaggcaggagagagcgtg
accttgtcctgcagctcccggagctcctatgacatgtaccatctatccagggagggggga
gcccatgaacgtaggctccctgcagtgcgcaaggtcaacagaacattccaggcagatttc
cctctgggccctgccacccacggagggacctacagatgcttcggctctttccgtcactct
ccctacgagtggtcagacccgagtgacccactgcttgtttctgtcacaggaaacccttca
agtagttggccttcacccacagaaccaagctccaaatctggtaaccccagacacctgcac
attctgattgggacctcagtggtcatcatcctcttcatcctcctcctcttctttctcctt
catctctggtgctccaacaaaaaaaatgctgctgtaatggaccaagagcctgcagggaac
agaacagccaacagcgaggactctgatgaacaagaccctgaggaggtgacatacgcacag
ttggatcactgcgttttcacacagagaaaaatcactcgcccttctcagaggcccaagaca
ccccctacagataccatcttgtacacggaacttccaaatgctaagcccagatccaaagtt
gtctcctgcccatga

KEGG   Homo sapiens (human): 3812
Entry
3812              CDS       T01001                                 

Gene name
KIR3DL2, 3DL2, CD158K, KIR-3DL2, NKAT-4, NKAT4, NKAT4B, p140
Definition
(RefSeq) killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2
  KO
K07980  killer cell immunoglobulin-like receptor 3DL
Organism
hsa  Homo sapiens (human)
Pathway
hsa04612  Antigen processing and presentation
hsa04650  Natural killer cell mediated cytotoxicity
hsa05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    3812 (KIR3DL2)
   04612 Antigen processing and presentation
    3812 (KIR3DL2)
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    3812 (KIR3DL2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    3812 (KIR3DL2)
CD molecules [BR:hsa04090]
 Proteins
  3812 (KIR3DL2)
SSDB
Motif
Pfam: ig Ig_2 Ig_3 MAP17 SIT
Other DBs
NCBI-GeneID: 3812
NCBI-ProteinID: NP_006728
OMIM: 604947
HGNC: 6339
Ensembl: ENSG00000240403
Vega: OTTHUMG00000065935
Pharos: P43630(Tbio)
UniProt: P43630 A0A0U1WNF3 Q8NHK6
LinkDB
Position
19q13.42
AA seq 455 aa
MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML
YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN
HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF
SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENV
TLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRAL
PCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLL
YRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKT
PLTDTSVYTELPNAEPRSKVVSCPRAPQSGLEGVF
NT seq 1368 nt   +upstreamnt  +downstreamnt
atgtcgctcacggtcgtcagcatggcgtgcgttgggttcttcttgctgcagggggcctgg
ccactcatgggtggtcaggacaaacccttcctgtctgcccggcccagcactgtggtgcct
cgaggaggacacgtggctcttcagtgtcactatcgtcgtgggtttaacaatttcatgctg
tacaaagaagacagaagccacgttcccatcttccacggcagaatattccaggagagcttc
atcatgggccctgtgaccccagcacatgcagggacctacagatgtcggggttcacgccca
cactccctcactgggtggtcggcacccagcaaccccctggtgatcatggtcacaggaaac
cacagaaaaccttccctcctggcccacccagggcccctgctgaaatcaggagagacagtc
atcctgcaatgttggtcagatgtcatgtttgagcacttctttctgcacagagaggggatc
tctgaggacccctcacgcctcgttggacagatccatgatggggtctccaaggccaacttc
tccatcggtcccttgatgcctgtccttgcaggaacctacagatgttatggttctgttcct
cactccccctatcagttgtcagctcccagtgaccccctggacatcgtgatcacaggtcta
tatgagaaaccttctctctcagcccagccgggccccacggttcaggcaggagagaacgtg
accttgtcctgtagctcctggagctcctatgacatctaccatctgtccagggaaggggag
gcccatgaacgtaggctccgtgcagtgcccaaggtcaacagaacattccaggcagacttt
cctctgggccctgccacccacggagggacctacagatgcttcggctctttccgtgccctg
ccctgcgtgtggtcaaactcaagtgacccactgcttgtttctgtcacaggaaacccttca
agtagttggccttcacccacagaaccaagctccaaatctggtatctgcagacacctgcat
gttctgattgggacctcagtggtcatcttcctcttcatcctcctcctcttctttctcctt
tatcgctggtgctccaacaaaaagaatgctgctgtaatggaccaagagcctgcgggggac
agaacagtgaataggcaggactctgatgaacaagaccctcaggaggtgacgtacgcacag
ttggatcactgcgttttcatacagagaaaaatcagtcgcccttctcagaggcccaagaca
cccctaacagataccagcgtgtacacggaacttccaaatgctgagcccagatccaaagtt
gtctcctgcccacgagcaccacagtcaggtcttgagggggttttctag

KEGG   Homo sapiens (human): 3821
Entry
3821              CDS       T01001                                 

Gene name
KLRC1, CD159A, NKG2, NKG2A
Definition
(RefSeq) killer cell lectin like receptor C1
  KO
K06541  killer cell lectin-like receptor subfamily C1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04612  Antigen processing and presentation
hsa04650  Natural killer cell mediated cytotoxicity
hsa05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    3821 (KLRC1)
   04612 Antigen processing and presentation
    3821 (KLRC1)
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    3821 (KLRC1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    3821 (KLRC1)
   04091 Lectins [BR:hsa04091]
    3821 (KLRC1)
CD molecules [BR:hsa04090]
 Proteins
  3821 (KLRC1)
Lectins [BR:hsa04091]
 C-Type lectins
  Gropu 5: NK-cell receptors
   3821 (KLRC1)
SSDB
Motif
Pfam: Lectin_C UL45 Chordopox_A33R
Other DBs
NCBI-GeneID: 3821
NCBI-ProteinID: NP_002250
OMIM: 161555
HGNC: 6374
Ensembl: ENSG00000134545
Vega: OTTHUMG00000168584
Pharos: P26715(Tbio)
UniProt: P26715
LinkDB
Structure
PDB: 
3BDW 3CDG 3CII

Position
12p13.2
AA seq 233 aa
MDNQGVIYSDLNLPPNPKRQQRKPKGNKNSILATEQEITYAELNLQKASQDFQGNDKTYH
CKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSTLIQRHNNSSLNTRTQKARHCGHCP
EEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRN
SSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL
NT seq 702 nt   +upstreamnt  +downstreamnt
atggataaccaaggagtaatctactcagacctgaatctgcccccaaacccaaagaggcag
caacgaaaacctaaaggcaataaaaactccattttagcaactgaacaggaaataacctat
gcggaattaaaccttcaaaaagcttctcaggattttcaagggaatgacaaaacctatcac
tgcaaagatttaccatcagctccagagaagctcattgttgggatcctgggaattatctgt
cttatcttaatggcctctgtggtaacgatagttgttattccctctacattaatacagagg
cacaacaattcttccctgaatacaagaactcagaaagcacgtcattgtggccattgtcct
gaggagtggattacatattccaacagttgttactacattggtaaggaaagaagaacttgg
gaagagagtttgctggcctgtacttcgaagaactccagtctgctttctatagataatgaa
gaagaaatgaaatttctgtccatcatttcaccatcctcatggattggtgtgtttcgtaac
agcagtcatcatccatgggtgacaatgaatggtttggctttcaaacatgagataaaagac
tcagataatgctgaacttaactgtgcagtgctacaagtaaatcgacttaaatcagcccag
tgtggatcttcaataatatatcattgtaagcataagctttag

KEGG   Homo sapiens (human): 3824
Entry
3824              CDS       T01001                                 

Gene name
KLRD1, CD94
Definition
(RefSeq) killer cell lectin like receptor D1
  KO
K06516  killer cell lectin-like receptor subfamily D member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04612  Antigen processing and presentation
hsa04650  Natural killer cell mediated cytotoxicity
hsa05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    3824 (KLRD1)
   04612 Antigen processing and presentation
    3824 (KLRD1)
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    3824 (KLRD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    3824 (KLRD1)
   04091 Lectins [BR:hsa04091]
    3824 (KLRD1)
CD molecules [BR:hsa04090]
 Proteins
  3824 (KLRD1)
Lectins [BR:hsa04091]
 C-Type lectins
  Gropu 5: NK-cell receptors
   3824 (KLRD1)
SSDB
Motif
Pfam: Lectin_C Chordopox_A33R Ly49
Other DBs
NCBI-GeneID: 3824
NCBI-ProteinID: NP_001107868
OMIM: 602894
HGNC: 6378
Ensembl: ENSG00000134539
Vega: OTTHUMG00000168419
Pharos: Q13241(Tbio)
UniProt: Q53ZY6
LinkDB
Structure
PDB: 
3BDW 1B6E 3CDG 3CII

Position
12p13.2
AA seq 179 aa
MAVFKTTLWRLISGTLGIICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS
CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLS
YSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI
NT seq 540 nt   +upstreamnt  +downstreamnt
atggcagtgtttaagaccactctgtggaggttaatttctgggaccttagggataatatgc
ctttcgttgatgtctacgttgggaattttgttgaaaaattcttttactaaactgagtatt
gagccagcatttactccaggacccaacatagaactccagaaagactctgactgctgttct
tgccaagaaaaatgggttgggtaccggtgcaactgttacttcatttccagtgaacagaaa
acttggaacgaaagtcggcatctctgtgcttctcagaaatccagcctgcttcagcttcaa
aacacagatgaactggattttatgagctccagtcaacaattttactggattggactctct
tacagtgaggagcacaccgcctggttgtgggagaatggctctgcactctcccagtatcta
tttccatcatttgaaacttttaatacaaagaactgcatagcgtataatccaaatggaaat
gctttagatgaatcctgtgaagataaaaatcgttatatctgtaagcaacagctcatttaa

KEGG   Homo sapiens (human): 57292
Entry
57292             CDS       T01001                                 

Gene name
KIR2DL5A, CD158F, KIR2DL5, KIR2DL5.1, KIR2DL5.3
Definition
(RefSeq) killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A
  KO
K24232  killer cell immunoglobulin-like receptor 2DL5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04612  Antigen processing and presentation
hsa04650  Natural killer cell mediated cytotoxicity
hsa05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    57292 (KIR2DL5A)
   04612 Antigen processing and presentation
    57292 (KIR2DL5A)
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    57292 (KIR2DL5A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    57292 (KIR2DL5A)
CD molecules [BR:hsa04090]
 Proteins
  57292 (KIR2DL5A)
SSDB
Motif
Pfam: ig Ig_2 Ig_3 V-set Shisa SIT WBP-1 Tweety
Other DBs
NCBI-GeneID: 57292
NCBI-ProteinID: NP_065396
OMIM: 605305
HGNC: 16345
Pharos: Q8N109(Tdark)
UniProt: Q8N109 A0A191URI1
LinkDB
Position
19p13.3
AA seq 375 aa
MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL
YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL
FGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQADF
PLGPATHGGTYTCFGSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLH
ILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQEVTYAQ
LDHCVFTQTKITSPSQRPKTPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETTAL
SQNRVASSHVPAAGI
NT seq 1128 nt   +upstreamnt  +downstreamnt
atgtcgctcatggtcatcagcatggcgtgtgttgggttcttcttgctgcagggggcctgg
acacatgagggtggtcaggacaagcccttgctgtctgcctggcccagcgctgtggtgcct
cgaggaggacatgtgactcttctgtgtcgctctcgtcttgggtttaccatcttcagtctg
tacaaagaagatggggtgcctgtccctgagctctacaacaaaatattctggaagagcatc
ctcatgggccctgtgacccctgcacacgcagggacctacagatgtcggggttcacaccca
cgctcccccattgagtggtcagcacccagcaaccccctggtgatcgtggtcacaggtcta
tttgggaaaccttcactctcagcccagccgggccccacggttcgcacaggagagaacgtg
accttgtcctgcagctccaggagctcatttgacatgtaccatctatccagggaggggagg
gcccatgaacctaggctccctgcagtgcccagcgtcaatggaacattccaggctgacttt
cctctgggccctgccacccacggagggacctacacatgcttcggctctctccatgactca
ccctatgagtggtcagacccgagtgacccactgcttgtttctgtcacaggaaactcttca
agtagttcatcttcacccactgaaccaagctccaaaactggtatccgcagacacctgcac
attctgattgggacctcagtggctatcatcctcttcatcatcctcttcttctttctcctt
cattgctgctgctccaacaaaaagaatgctgctgtaatggaccaagagcctgccggggac
agaacagtgaacagggaggactctgatgatcaagaccctcaggaggtgacatatgcacag
ttggatcactgcgttttcacacagacaaaaatcacttccccttctcagaggcccaagaca
cctccaacagataccaccatgtacatggaacttccaaatgctaagccaagatcattgtct
cctgcccataagcaccacagtcaggccttgaggggatcttctagggagacaacagccctg
tctcaaaaccgggttgctagctcccatgtaccagcagctggaatctga

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