Homo sapiens (human): 130399
Entry
130399 CDS
T01001
Gene name
ACVR1C, ACVRLK7, ALK7
Definition
(RefSeq) activin A receptor type 1C
KO
K13568
activin receptor type-1C [EC:
2.7.11.30
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04350
TGF-beta signaling pathway
hsa04550
Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
130399 (ACVR1C)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
130399 (ACVR1C)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
130399 (ACVR1C)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
130399 (ACVR1C)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
130399 (ACVR1C)
Protein kinases [BR:
hsa01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR1 family [OT]
130399 (ACVR1C)
SSDB
Motif
Pfam:
Pkinase_Tyr
Pkinase
TGF_beta_GS
Pkinase_fungal
Other DBs
NCBI-GeneID:
130399
NCBI-ProteinID:
NP_660302
OMIM:
608981
HGNC:
18123
Ensembl:
ENSG00000123612
Vega:
OTTHUMG00000131964
Pharos:
Q8NER5
(Tbio)
UniProt:
Q8NER5
LinkDB
Position
2q24.1
AA seq
493 aa
MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVI
KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPMELAIIITV
PVCLLSIAAMLTVWACQGRQCSYRKKKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSG
SGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQ
TVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIA
SGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQN
PKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYD
MVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKK
TISQLCVKEDCKA
NT seq
1482 nt
+upstream
nt +downstream
nt
atgacccgggcgctctgctcagcgctccgccaggctctcctgctgctcgcagcggccgcc
gagctctcgccaggactgaagtgtgtatgtcttttgtgtgattcttcaaacttcacctgc
caaacagaaggagcatgttgggcatcagtcatgctaaccaatggaaaagagcaggtgatc
aaatcctgtgtctcccttccagaactgaatgctcaagtcttctgtcatagttccaacaat
gttaccaaaaccgaatgctgcttcacagatttttgcaacaacataacactgcaccttcca
acagcatcaccaaatgccccaaaacttggacccatggagctggccatcattattactgtg
cctgtttgcctcctgtccatagctgcgatgctgacagtatgggcatgccagggtcgacag
tgctcctacaggaagaaaaagagaccaaatgtggaggaaccactctctgagtgcaatctg
gtaaatgctggaaaaactctgaaagatctgatttatgatgtgaccgcctctggatctggc
tctggtctacctctgttggttcaaaggacaattgcaaggacgattgtgcttcaggaaata
gtaggaaaaggtagatttggtgaggtgtggcatggaagatggtgtggggaagatgtggct
gtgaaaatattctcctccagagatgaaagatcttggtttcgtgaggcagaaatttaccag
acggtcatgctgcgacatgaaaacatccttggtttcattgctgctgacaacaaagataat
ggaacttggactcaactttggctggtatctgaatatcatgaacagggctccttatatgac
tatttgaatagaaatatagtgaccgtggctggaatgatcaagctggcgctctcaattgct
agtggtctggcacaccttcatatggagattgttggtacacaaggtaaacctgctattgct
catcgagacataaaatcaaagaatatcttagtgaaaaagtgtgaaacttgtgccatagcg
gacttagggttggctgtgaagcatgattcaatactgaacactatcgacatacctcagaat
cctaaagtgggaaccaagaggtatatggctcctgaaatgcttgatgatacaatgaatgtg
aatatctttgagtccttcaaacgagctgacatctattctgttggtctggtttactgggaa
atagcccggaggtgttcagtcggaggaattgttgaggagtaccaattgccttattatgac
atggtgccttcagatccctcgatagaggaaatgagaaaggttgtttgtgaccagaagttt
cgaccaagtatcccaaaccagtggcaaagttgtgaagcactccgagtcatggggagaata
atgcgtgagtgttggtatgccaacggagcggcccgcctaactgctcttcgtattaagaag
actatatctcaactttgtgtcaaagaagactgcaaagcctaa
DBGET
integrated database retrieval system
