Homo sapiens (human): 1551
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Entry
1551 CDS
T01001
Gene name
CYP3A7, CP37, CYPIIIA7, P-450(HFL33), P-450111A7, P450-HFLA, P450HLp2
Definition
(RefSeq) cytochrome P450 family 3 subfamily A member 7
KO
K17691
cytochrome P450 family 3 subfamily A polypeptide 7 [EC:
1.14.14.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00140
Steroid hormone biosynthesis
hsa00830
Retinol metabolism
hsa01100
Metabolic pathways
hsa05204
Chemical carcinogenesis
Drug target
Cobicistat:
D09881
<US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
1551 (CYP3A7)
09108 Metabolism of cofactors and vitamins
00830 Retinol metabolism
1551 (CYP3A7)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis
1551 (CYP3A7)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
hsa00199
]
1551 (CYP3A7)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.1 unspecific monooxygenase
1551 (CYP3A7)
Cytochrome P450 [BR:
hsa00199
]
Cytochrome P450, animal type
CYP3 family
1551 (CYP3A7)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
p450
Motif
Other DBs
NCBI-GeneID:
1551
NCBI-ProteinID:
NP_000756
OMIM:
605340
HGNC:
2640
Ensembl:
ENSG00000160870
Vega:
OTTHUMG00000156726
Pharos:
P24462
(Tclin)
UniProt:
P24462
LinkDB
All DBs
Position
7q22.1
AA seq
503 aa
AA seq
DB search
MDLIPNLAVETWLLLAVSLILLYLYGTRTHGLFKKLGIPGPTPLPFLGNALSFRKGYWTF
DMECYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISI
AEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYS
MDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPFLTPILEALNITV
FPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSI
IFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVV
NETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFS
KKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLRFG
GLLLTEKPIVLKAESRDETVSGA
NT seq
1512 nt
NT seq
+upstream
nt +downstream
nt
atggatctcatcccaaacttggccgtggaaacctggcttctcctggctgtcagcctgata
ctcctctatctatatggaacccgtacacatggactttttaagaagcttggaattccaggg
cccacacctctgccttttttgggaaatgctttgtccttccgtaagggctattggacgttt
gacatggaatgttataaaaagtatagaaaagtctggggtatttatgactgtcaacagcct
atgctggctatcacagatcccgacatgatcaaaacagtgctagtgaaagaatgttattct
gtcttcacaaaccggaggcctttcgggccagtgggatttatgaaaaatgccatctctata
gctgaggatgaagaatggaagagaatacgatcattgctgtctccaacattcaccagcgga
aaactcaaggagatggtccctatcattgcccagtatggagatgtgttggtgagaaatctg
aggcgggaagcagagacaggcaagcctgtcaccttgaaacacgtctttggggcctacagc
atggatgtgatcactagcacatcatttggagtgagcatcgactctctcaacaatccacaa
gacccctttgtggaaaacaccaagaagcttttaagatttaatccattagatccattcgtt
ctctcaataaaagtctttccattccttaccccaattcttgaagcattaaatatcactgtg
tttccaagaaaagttataagttttctaacaaaatctgtaaaacagataaaagaaggtcgc
ctcaaagagacacaaaagcaccgagtggatttccttcagctgatgattgactctcagaat
tcaaaagactctgagacccacaaagctctgtctgatctggagctcatggcccaatcaatt
atctttatttttgctggctatgaaaccacgagcagtgttctctccttcattatatatgaa
ctggccactcaccctgatgtccagcagaaagtgcagaaggaaattgatacagttttaccc
aataaggcaccacccacctatgatactgtgctacagttggagtatcttgacatggtggtg
aatgaaacactcagattattcccagttgctatgagacttgagagggtctgcaaaaaagat
gttgaaatcaatgggatgtttattcccaaaggggtggtggtgatgattccaagctatgtt
cttcatcatgacccaaagtactggacagagcctgagaagttcctccctgaaaggttcagt
aaaaagaacaaggacaacatagatccttacatatacacaccctttggaagtggacccaga
aactgcattggcatgaggtttgctctcgtgaacatgaaacttgctctagtcagagtcctt
cagaacttctccttcaaaccttgtaaagaaacacagatccccctgaaattacgctttgga
ggacttcttctaacagaaaaacccattgttctaaaggctgagtcaagggatgagaccgta
agtggagcctga
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