Entry |
|
Gene name |
CALM1, CALML2, CAM2, CAM3, CAMB, CAMC, CAMI, CAMIII, CPVT4, DD132, LQT14, PHKD, caM
|
Definition |
|
KO |
|
Organism |
|
Pathway |
hsa04070 | Phosphatidylinositol signaling system |
hsa04261 | Adrenergic signaling in cardiomyocytes |
hsa04270 | Vascular smooth muscle contraction |
hsa04625 | C-type lectin receptor signaling pathway |
hsa04750 | Inflammatory mediator regulation of TRP channels |
hsa04925 | Aldosterone synthesis and secretion |
hsa05022 | Pathways of neurodegeneration - multiple diseases |
hsa05163 | Human cytomegalovirus infection |
hsa05167 | Kaposi sarcoma-associated herpesvirus infection |
hsa05170 | Human immunodeficiency virus 1 infection |
hsa05418 | Fluid shear stress and atherosclerosis |
|
Network |
nt06120 Calcium signaling (viruses and bacteria) nt06124 Chemokine signaling (viruses) nt06150 Cytokine-cytokine receptor interaction (viruses) nt06160 Human T-cell leukemia virus 1 (HTLV-1) nt06161 Human immunodeficiency virus type 1 (HIV-1) nt06164 Kaposi sarcoma-associated herpesvirus (KSHV) nt06165 Epstein-Barr virus (EBV) nt06167 Human cytomegalovirus (HCMV) nt06220 Calcium signaling nt06273 Glioma nt06316 Angiotensin-aldosterone signaling |
Element |
N00026 | EGF-EGFR-PLCG-CAMK signaling pathway |
N00027 | Amplified EGFR to PLCG-CAMK signaling pathway |
N00028 | PDGF-PDGFR-PLCG-CAMK signaling pathway |
N00029 | Amplified PDGFR to PLCG-CAMK signaling pathway |
N00147 | EGF-EGFR-PLCG-calcineurin signaling pathway |
N00172 | KSHV K15 to PLCG-calcineurin signaling pathway |
N00180 | KSHV K1 to PLCG-calcineurin signaling pathway |
N00301 | Angiotensin-aldosterone signaling pathway |
N00302 | Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway |
N00303 | Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway |
N00304 | Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway |
N00305 | Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway |
N00401 | CXCR4-GNAQ-PLCB/G-calcineurin signaling pathway |
N00402 | HCMV US28 to GNAQ-PLCB/G-calcineurin signaling pathway |
N00432 | HIV gp120 to CXCR4-GNAQ-PLCB/G-calcineurin |
N00487 | BCR-PLCG-Calcineurin signaling pathway |
N00490 | HTLV-1 p12 to calcineurin signaling pathway |
N01106 | TCR-NFAT signaling pathway |
|
Disease |
H01019 | Catecholaminergic polymorphic ventricular tachycardia |
|
Drug target |
|
Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
801 (CALM1)
04015 Rap1 signaling pathway
801 (CALM1)
04371 Apelin signaling pathway
801 (CALM1)
04020 Calcium signaling pathway
801 (CALM1)
04070 Phosphatidylinositol signaling system
801 (CALM1)
04024 cAMP signaling pathway
801 (CALM1)
04022 cGMP-PKG signaling pathway
801 (CALM1)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
801 (CALM1)
04218 Cellular senescence
801 (CALM1)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
801 (CALM1)
09152 Endocrine system
04910 Insulin signaling pathway
801 (CALM1)
04922 Glucagon signaling pathway
801 (CALM1)
04912 GnRH signaling pathway
801 (CALM1)
04915 Estrogen signaling pathway
801 (CALM1)
04921 Oxytocin signaling pathway
801 (CALM1)
04916 Melanogenesis
801 (CALM1)
04924 Renin secretion
801 (CALM1)
04925 Aldosterone synthesis and secretion
801 (CALM1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
801 (CALM1)
04270 Vascular smooth muscle contraction
801 (CALM1)
09154 Digestive system
04970 Salivary secretion
801 (CALM1)
04971 Gastric acid secretion
801 (CALM1)
09156 Nervous system
04728 Dopaminergic synapse
801 (CALM1)
04720 Long-term potentiation
801 (CALM1)
04722 Neurotrophin signaling pathway
801 (CALM1)
09157 Sensory system
04744 Phototransduction
801 (CALM1)
04740 Olfactory transduction
801 (CALM1)
04750 Inflammatory mediator regulation of TRP channels
801 (CALM1)
09159 Environmental adaptation
04713 Circadian entrainment
801 (CALM1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
801 (CALM1)
09162 Cancer: specific types
05214 Glioma
801 (CALM1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
801 (CALM1)
05163 Human cytomegalovirus infection
801 (CALM1)
05167 Kaposi sarcoma-associated herpesvirus infection
801 (CALM1)
09171 Infectious disease: bacterial
05133 Pertussis
801 (CALM1)
05152 Tuberculosis
801 (CALM1)
09164 Neurodegenerative disease
05010 Alzheimer disease
801 (CALM1)
05012 Parkinson disease
801 (CALM1)
05022 Pathways of neurodegeneration - multiple diseases
801 (CALM1)
09165 Substance dependence
05031 Amphetamine addiction
801 (CALM1)
05034 Alcoholism
801 (CALM1)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
801 (CALM1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:hsa01009]
801 (CALM1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:hsa04131]
801 (CALM1)
03036 Chromosome and associated proteins [BR:hsa03036]
801 (CALM1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
801 (CALM1)
Protein phosphatases and associated proteins [BR:hsa01009]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Calcineurin (PPP3/ PP2B)
Regulatory subunits
801 (CALM1)
Membrane trafficking [BR:hsa04131]
Exocytosis
Small GTPases and associated proteins
Rab associated proteins
801 (CALM1)
Chromosome and associated proteins [BR:hsa03036]
Eukaryotic type
Centrosome formation and ciliogenesis proteins
Centrosome duplication proteins
Centriole replication proteins
801 (CALM1)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
801 (CALM1)
|
SSDB |
|
Motif |
|
Other DBs |
|
LinkDB |
|
Structure |
PDB: |
Position |
14q32.11
|
AA seq |
149 aa
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
EVDEMIREADIDGDGQVNYEEFVQMMTAK |
NT seq |
450 nt +upstreamnt +downstreamnt
atggctgatcagctgaccgaagaacagattgctgaattcaaggaagccttctccctattt
gataaagatggcgatggcaccatcacaacaaaggaacttggaactgtcatgaggtcactg
ggtcagaacccaacagaagctgaattgcaggatatgatcaatgaagtggatgctgatggt
aatggcaccattgacttccccgaatttttgactatgatggctagaaaaatgaaagataca
gatagtgaagaagaaatccgtgaggcattccgagtctttgacaaggatggcaatggttat
atcagtgcagcagaactacgtcacgtcatgacaaacttaggagaaaaactaacagatgaa
gaagtagatgaaatgatcagagaagcagatattgatggagacggacaagtcaactatgaa
gaattcgtacagatgatgactgcaaaatga |