KEGG   Homo sapiens (human): 163688Help
Entry
163688            CDS       T01001                                 

Gene name
CALML6, CAGLP
Definition
(RefSeq) calmodulin like 6
  KO
K02183  calmodulin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04070  Phosphatidylinositol signaling system
hsa04114  Oocyte meiosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04371  Apelin signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04713  Circadian entrainment
hsa04720  Long-term potentiation
hsa04722  Neurotrophin signaling pathway
hsa04728  Dopaminergic synapse
hsa04740  Olfactory transduction
hsa04744  Phototransduction
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04910  Insulin signaling pathway
hsa04912  GnRH signaling pathway
hsa04915  Estrogen signaling pathway
hsa04916  Melanogenesis
hsa04921  Oxytocin signaling pathway
hsa04922  Glucagon signaling pathway
hsa04924  Renin secretion
hsa04925  Aldosterone synthesis and secretion
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa05010  Alzheimer disease
hsa05031  Amphetamine addiction
hsa05034  Alcoholism
hsa05133  Pertussis
hsa05152  Tuberculosis
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
hsa05214  Glioma
hsa05418  Fluid shear stress and atherosclerosis
Drug target
Lubeluzole: D04789
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    163688 (CALML6)
   04015 Rap1 signaling pathway
    163688 (CALML6)
   04371 Apelin signaling pathway
    163688 (CALML6)
   04020 Calcium signaling pathway
    163688 (CALML6)
   04070 Phosphatidylinositol signaling system
    163688 (CALML6)
   04024 cAMP signaling pathway
    163688 (CALML6)
   04022 cGMP-PKG signaling pathway
    163688 (CALML6)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    163688 (CALML6)
   04218 Cellular senescence
    163688 (CALML6)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    163688 (CALML6)
  09152 Endocrine system
   04910 Insulin signaling pathway
    163688 (CALML6)
   04922 Glucagon signaling pathway
    163688 (CALML6)
   04912 GnRH signaling pathway
    163688 (CALML6)
   04915 Estrogen signaling pathway
    163688 (CALML6)
   04921 Oxytocin signaling pathway
    163688 (CALML6)
   04916 Melanogenesis
    163688 (CALML6)
   04924 Renin secretion
    163688 (CALML6)
   04925 Aldosterone synthesis and secretion
    163688 (CALML6)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    163688 (CALML6)
   04270 Vascular smooth muscle contraction
    163688 (CALML6)
  09154 Digestive system
   04970 Salivary secretion
    163688 (CALML6)
   04971 Gastric acid secretion
    163688 (CALML6)
  09156 Nervous system
   04728 Dopaminergic synapse
    163688 (CALML6)
   04720 Long-term potentiation
    163688 (CALML6)
   04722 Neurotrophin signaling pathway
    163688 (CALML6)
  09157 Sensory system
   04744 Phototransduction
    163688 (CALML6)
   04740 Olfactory transduction
    163688 (CALML6)
   04750 Inflammatory mediator regulation of TRP channels
    163688 (CALML6)
  09159 Environmental adaptation
   04713 Circadian entrainment
    163688 (CALML6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    163688 (CALML6)
  09162 Cancer: specific types
   05214 Glioma
    163688 (CALML6)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    163688 (CALML6)
  09165 Substance dependence
   05031 Amphetamine addiction
    163688 (CALML6)
   05034 Alcoholism
    163688 (CALML6)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    163688 (CALML6)
  09171 Infectious disease: bacterial
   05133 Pertussis
    163688 (CALML6)
   05152 Tuberculosis
    163688 (CALML6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    163688 (CALML6)
   05163 Human cytomegalovirus infection
    163688 (CALML6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    163688 (CALML6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    163688 (CALML6)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    163688 (CALML6)
   03036 Chromosome and associated proteins [BR:hsa03036]
    163688 (CALML6)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    163688 (CALML6)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     163688 (CALML6)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    163688 (CALML6)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Centriole replication proteins
     163688 (CALML6)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   163688 (CALML6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EF-hand_1 EF-hand_7 EF-hand_6 EF-hand_8 EF-hand_9 EF-hand_5 EF-hand_4
Motif
Other DBs
NCBI-GeneID: 163688
NCBI-ProteinID: NP_619650
OMIM: 610171
HGNC: 24193
Ensembl: ENSG00000169885
Vega: OTTHUMG00000000943
Pharos: Q8TD86(Tdark)
UniProt: Q8TD86
LinkDB All DBs
Position
1p36.33
AA seq 181 aa AA seqDB search
MGLQQEISLQPWCHHPAESCQTTTDMTERLSAEQIKEYKGVFEMFDEEGNGEVKTGELEW
LMSLLGINPTKSELASMAKDVDRDNKGFFNCDGFLALMGVYHEKAQNQESELRAAFRVFD
KEGKGYIDWNTLKYVLMNAGEPLNEVEAEQMMKEADKDGDRTIDYEEFVAMMTGESFKLI
Q
NT seq 546 nt NT seq  +upstreamnt  +downstreamnt
atgggtcttcaacaagaaatctcactgcagccctggtgtcaccaccctgcagaatcctgt
cagacaaccaccgacatgacagagcgcctgtcggctgagcagatcaaggagtacaaggga
gtctttgagatgttcgacgaagagggcaacggggaggtgaagacgggggagctggagtgg
ctcatgagcctgctgggtatcaaccccaccaagagtgagctggcctcaatggccaaggat
gtggacagagacaacaaagggttcttcaactgcgatggtttcctggcactaatgggagtt
taccatgagaaggcccagaaccaggagagcgagctgagggcggcattccgtgtctttgac
aaagagggcaagggctacattgactggaacacactcaagtacgtgctaatgaacgcaggg
gagcccctcaacgaggtggaggcggagcagatgatgaaggaggccgacaaggatggggac
aggaccatcgactatgaggagtttgtggccatgatgacgggggagtccttcaagctgatc
cagtag

KEGG   Homo sapiens (human): 51806Help
Entry
51806             CDS       T01001                                 

Gene name
CALML5, CLSP
Definition
(RefSeq) calmodulin like 5
  KO
K02183  calmodulin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04070  Phosphatidylinositol signaling system
hsa04114  Oocyte meiosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04371  Apelin signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04713  Circadian entrainment
hsa04720  Long-term potentiation
hsa04722  Neurotrophin signaling pathway
hsa04728  Dopaminergic synapse
hsa04740  Olfactory transduction
hsa04744  Phototransduction
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04910  Insulin signaling pathway
hsa04912  GnRH signaling pathway
hsa04915  Estrogen signaling pathway
hsa04916  Melanogenesis
hsa04921  Oxytocin signaling pathway
hsa04922  Glucagon signaling pathway
hsa04924  Renin secretion
hsa04925  Aldosterone synthesis and secretion
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa05010  Alzheimer disease
hsa05031  Amphetamine addiction
hsa05034  Alcoholism
hsa05133  Pertussis
hsa05152  Tuberculosis
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
hsa05214  Glioma
hsa05418  Fluid shear stress and atherosclerosis
Drug target
Lubeluzole: D04789
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    51806 (CALML5)
   04015 Rap1 signaling pathway
    51806 (CALML5)
   04371 Apelin signaling pathway
    51806 (CALML5)
   04020 Calcium signaling pathway
    51806 (CALML5)
   04070 Phosphatidylinositol signaling system
    51806 (CALML5)
   04024 cAMP signaling pathway
    51806 (CALML5)
   04022 cGMP-PKG signaling pathway
    51806 (CALML5)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    51806 (CALML5)
   04218 Cellular senescence
    51806 (CALML5)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    51806 (CALML5)
  09152 Endocrine system
   04910 Insulin signaling pathway
    51806 (CALML5)
   04922 Glucagon signaling pathway
    51806 (CALML5)
   04912 GnRH signaling pathway
    51806 (CALML5)
   04915 Estrogen signaling pathway
    51806 (CALML5)
   04921 Oxytocin signaling pathway
    51806 (CALML5)
   04916 Melanogenesis
    51806 (CALML5)
   04924 Renin secretion
    51806 (CALML5)
   04925 Aldosterone synthesis and secretion
    51806 (CALML5)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    51806 (CALML5)
   04270 Vascular smooth muscle contraction
    51806 (CALML5)
  09154 Digestive system
   04970 Salivary secretion
    51806 (CALML5)
   04971 Gastric acid secretion
    51806 (CALML5)
  09156 Nervous system
   04728 Dopaminergic synapse
    51806 (CALML5)
   04720 Long-term potentiation
    51806 (CALML5)
   04722 Neurotrophin signaling pathway
    51806 (CALML5)
  09157 Sensory system
   04744 Phototransduction
    51806 (CALML5)
   04740 Olfactory transduction
    51806 (CALML5)
   04750 Inflammatory mediator regulation of TRP channels
    51806 (CALML5)
  09159 Environmental adaptation
   04713 Circadian entrainment
    51806 (CALML5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    51806 (CALML5)
  09162 Cancer: specific types
   05214 Glioma
    51806 (CALML5)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    51806 (CALML5)
  09165 Substance dependence
   05031 Amphetamine addiction
    51806 (CALML5)
   05034 Alcoholism
    51806 (CALML5)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    51806 (CALML5)
  09171 Infectious disease: bacterial
   05133 Pertussis
    51806 (CALML5)
   05152 Tuberculosis
    51806 (CALML5)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    51806 (CALML5)
   05163 Human cytomegalovirus infection
    51806 (CALML5)
   05167 Kaposi sarcoma-associated herpesvirus infection
    51806 (CALML5)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    51806 (CALML5)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    51806 (CALML5)
   03036 Chromosome and associated proteins [BR:hsa03036]
    51806 (CALML5)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    51806 (CALML5)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     51806 (CALML5)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    51806 (CALML5)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Centriole replication proteins
     51806 (CALML5)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   51806 (CALML5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EF-hand_1 EF-hand_7 EF-hand_8 EF-hand_5 EF-hand_6 EF-hand_9 EF-hand_4 SPARC_Ca_bdg EF-hand_11 Dockerin_1 DUF5580 DUF2184 UPF0154
Motif
Other DBs
NCBI-GeneID: 51806
NCBI-ProteinID: NP_059118
OMIM: 605183
HGNC: 18180
Ensembl: ENSG00000178372
Vega: OTTHUMG00000017598
Pharos: Q9NZT1(Tbio)
UniProt: Q9NZT1 Q53H37
LinkDB All DBs
Structure
PDB: 

Position
10p15.1
AA seq 146 aa AA seqDB search
MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDG
DGEISFQEFLTAAKKARAGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELD
AMIREADVDQDGRVNYEEFARMLAQE
NT seq 441 nt NT seq  +upstreamnt  +downstreamnt
atggccggtgagctgactcctgaggaggaggcccagtacaaaaaggctttctccgcggtt
gacacggatggaaacggcaccatcaatgcccaggagctgggcgcggcgctgaaggccacg
ggcaagaacctctcggaggcccagctaaggaaactcatctccgaggttgacagcgacggc
gacggcgaaatcagcttccaggagttcctgacggcggcgaagaaggccagggccggcctg
gaggacctgcaggtcgccttccgcgccttcgaccaggatggcgacggccacatcaccgtg
gacgagctcaggcgggccatggcggggctggggcagccgctgccgcaggaggagctggac
gccatgatccgcgaggccgacgtggaccaggacgggcgggtgaactacgaggagttcgcg
aggatgctcgcccaggagtga

KEGG   Homo sapiens (human): 801Help
Entry
801               CDS       T01001                                 

Gene name
CALM1, CALML2, CAM2, CAM3, CAMB, CAMC, CAMI, CAMIII, CPVT4, DD132, LQT14, PHKD, caM
Definition
(RefSeq) calmodulin 1
  KO
K02183  calmodulin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04070  Phosphatidylinositol signaling system
hsa04114  Oocyte meiosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04371  Apelin signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04713  Circadian entrainment
hsa04720  Long-term potentiation
hsa04722  Neurotrophin signaling pathway
hsa04728  Dopaminergic synapse
hsa04740  Olfactory transduction
hsa04744  Phototransduction
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04910  Insulin signaling pathway
hsa04912  GnRH signaling pathway
hsa04915  Estrogen signaling pathway
hsa04916  Melanogenesis
hsa04921  Oxytocin signaling pathway
hsa04922  Glucagon signaling pathway
hsa04924  Renin secretion
hsa04925  Aldosterone synthesis and secretion
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa05010  Alzheimer disease
hsa05031  Amphetamine addiction
hsa05034  Alcoholism
hsa05133  Pertussis
hsa05152  Tuberculosis
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
hsa05214  Glioma
hsa05418  Fluid shear stress and atherosclerosis
Network
nt06120  Calcium signaling (virus)
nt06124  Chemokine signaling (virus)
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165  Epstein-Barr virus (EBV)
nt06167  Human cytomegalovirus (HCMV)
nt06220  Calcium signaling
nt06273  Glioma
nt06316  Angiotensin-aldosterone signaling
  Element
N00026  EGF-EGFR-PLCG-CAMK signaling pathway
N00027  Amplified EGFR to PLCG-CAMK signaling pathway
N00028  PDGF-PDGFR-PLCG-CAMK signaling pathway
N00029  Amplified PDGFR to PLCG-CAMK signaling pathway
N00147  EGF-EGFR-PLCG-calcineurin signaling pathway
N00172  KSHV K15 to PLCG-calcineurin signaling pathway
N00180  KSHV K1 to PLCG-calcineurin signaling pathway
N00301  Angiotensin-aldosterone signaling pathway
N00302  Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303  Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304  Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305  Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N00401  CXCR4-GNAQ-PLCB/G-calcineurin signaling pathway
N00402  HCMV US28 to GNAQ-PLCB/G-calcineurin signaling pathway
N00432  HIV gp120 to CXCR4-GNAQ-PLCB/G-calcineurin
N00487  BCR-PLCG-Calcineurin signaling pathway
N00490  HTLV-1 p12 to calcineurin signaling pathway
Disease
H00720  Long QT syndrome
H01019  Catecholaminergic polymorphic ventricular tachycardia
Drug target
Lubeluzole: D04789
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    801 (CALM1)
   04015 Rap1 signaling pathway
    801 (CALM1)
   04371 Apelin signaling pathway
    801 (CALM1)
   04020 Calcium signaling pathway
    801 (CALM1)
   04070 Phosphatidylinositol signaling system
    801 (CALM1)
   04024 cAMP signaling pathway
    801 (CALM1)
   04022 cGMP-PKG signaling pathway
    801 (CALM1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    801 (CALM1)
   04218 Cellular senescence
    801 (CALM1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    801 (CALM1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    801 (CALM1)
   04922 Glucagon signaling pathway
    801 (CALM1)
   04912 GnRH signaling pathway
    801 (CALM1)
   04915 Estrogen signaling pathway
    801 (CALM1)
   04921 Oxytocin signaling pathway
    801 (CALM1)
   04916 Melanogenesis
    801 (CALM1)
   04924 Renin secretion
    801 (CALM1)
   04925 Aldosterone synthesis and secretion
    801 (CALM1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    801 (CALM1)
   04270 Vascular smooth muscle contraction
    801 (CALM1)
  09154 Digestive system
   04970 Salivary secretion
    801 (CALM1)
   04971 Gastric acid secretion
    801 (CALM1)
  09156 Nervous system
   04728 Dopaminergic synapse
    801 (CALM1)
   04720 Long-term potentiation
    801 (CALM1)
   04722 Neurotrophin signaling pathway
    801 (CALM1)
  09157 Sensory system
   04744 Phototransduction
    801 (CALM1)
   04740 Olfactory transduction
    801 (CALM1)
   04750 Inflammatory mediator regulation of TRP channels
    801 (CALM1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    801 (CALM1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    801 (CALM1)
  09162 Cancer: specific types
   05214 Glioma
    801 (CALM1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    801 (CALM1)
  09165 Substance dependence
   05031 Amphetamine addiction
    801 (CALM1)
   05034 Alcoholism
    801 (CALM1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    801 (CALM1)
  09171 Infectious disease: bacterial
   05133 Pertussis
    801 (CALM1)
   05152 Tuberculosis
    801 (CALM1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    801 (CALM1)
   05163 Human cytomegalovirus infection
    801 (CALM1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    801 (CALM1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    801 (CALM1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    801 (CALM1)
   03036 Chromosome and associated proteins [BR:hsa03036]
    801 (CALM1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    801 (CALM1)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     801 (CALM1)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    801 (CALM1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Centriole replication proteins
     801 (CALM1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   801 (CALM1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EF-hand_1 EF-hand_7 EF-hand_8 EF-hand_6 EF-hand_5 EF-hand_9 EF-hand_4 SPARC_Ca_bdg EF-hand_11 UPF0154 EFhand_Ca_insen Dockerin_1 DUF1103 Caleosin DUF4497 TerB DUF5580 SurA_N_2 Poly_export DUF2267 SurA_N_3 Fe_hyd_lg_C MotA_activ
Motif
Other DBs
NCBI-GeneID: 801
NCBI-ProteinID: NP_008819
OMIM: 114180
HGNC: 1442
Ensembl: ENSG00000198668
Vega: OTTHUMG00000171044
UniProt: P0DP23 P0DP24 P0DP25 B4DJ51
LinkDB All DBs
Structure
PDB: 

Position
14q32.11
AA seq 149 aa AA seqDB search
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
EVDEMIREADIDGDGQVNYEEFVQMMTAK
NT seq 450 nt NT seq  +upstreamnt  +downstreamnt
atggctgatcagctgaccgaagaacagattgctgaattcaaggaagccttctccctattt
gataaagatggcgatggcaccatcacaacaaaggaacttggaactgtcatgaggtcactg
ggtcagaacccaacagaagctgaattgcaggatatgatcaatgaagtggatgctgatggt
aatggcaccattgacttccccgaatttttgactatgatggctagaaaaatgaaagataca
gatagtgaagaagaaatccgtgaggcattccgagtctttgacaaggatggcaatggttat
atcagtgcagcagaactacgtcacgtcatgacaaacttaggagaaaaactaacagatgaa
gaagtagatgaaatgatcagagaagcagatattgatggagacggacaagtcaactatgaa
gaattcgtacagatgatgactgcaaaatga

KEGG   Homo sapiens (human): 805Help
Entry
805               CDS       T01001                                 

Gene name
CALM2, CALM, CALML2, CAM1, CAM3, CAMC, CAMII, CAMIII, LQT15, PHKD, PHKD2, caM
Definition
(RefSeq) calmodulin 2
  KO
K02183  calmodulin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04070  Phosphatidylinositol signaling system
hsa04114  Oocyte meiosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04371  Apelin signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04713  Circadian entrainment
hsa04720  Long-term potentiation
hsa04722  Neurotrophin signaling pathway
hsa04728  Dopaminergic synapse
hsa04740  Olfactory transduction
hsa04744  Phototransduction
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04910  Insulin signaling pathway
hsa04912  GnRH signaling pathway
hsa04915  Estrogen signaling pathway
hsa04916  Melanogenesis
hsa04921  Oxytocin signaling pathway
hsa04922  Glucagon signaling pathway
hsa04924  Renin secretion
hsa04925  Aldosterone synthesis and secretion
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa05010  Alzheimer disease
hsa05031  Amphetamine addiction
hsa05034  Alcoholism
hsa05133  Pertussis
hsa05152  Tuberculosis
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
hsa05214  Glioma
hsa05418  Fluid shear stress and atherosclerosis
Network
nt06120  Calcium signaling (virus)
nt06124  Chemokine signaling (virus)
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165  Epstein-Barr virus (EBV)
nt06167  Human cytomegalovirus (HCMV)
nt06220  Calcium signaling
nt06273  Glioma
nt06316  Angiotensin-aldosterone signaling
  Element
N00026  EGF-EGFR-PLCG-CAMK signaling pathway
N00027  Amplified EGFR to PLCG-CAMK signaling pathway
N00028  PDGF-PDGFR-PLCG-CAMK signaling pathway
N00029  Amplified PDGFR to PLCG-CAMK signaling pathway
N00147  EGF-EGFR-PLCG-calcineurin signaling pathway
N00172  KSHV K15 to PLCG-calcineurin signaling pathway
N00180  KSHV K1 to PLCG-calcineurin signaling pathway
N00301  Angiotensin-aldosterone signaling pathway
N00302  Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303  Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304  Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305  Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N00401  CXCR4-GNAQ-PLCB/G-calcineurin signaling pathway
N00402  HCMV US28 to GNAQ-PLCB/G-calcineurin signaling pathway
N00432  HIV gp120 to CXCR4-GNAQ-PLCB/G-calcineurin
N00487  BCR-PLCG-Calcineurin signaling pathway
N00490  HTLV-1 p12 to calcineurin signaling pathway
Disease
H00720  Long QT syndrome
Drug target
Lubeluzole: D04789
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    805 (CALM2)
   04015 Rap1 signaling pathway
    805 (CALM2)
   04371 Apelin signaling pathway
    805 (CALM2)
   04020 Calcium signaling pathway
    805 (CALM2)
   04070 Phosphatidylinositol signaling system
    805 (CALM2)
   04024 cAMP signaling pathway
    805 (CALM2)
   04022 cGMP-PKG signaling pathway
    805 (CALM2)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    805 (CALM2)
   04218 Cellular senescence
    805 (CALM2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    805 (CALM2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    805 (CALM2)
   04922 Glucagon signaling pathway
    805 (CALM2)
   04912 GnRH signaling pathway
    805 (CALM2)
   04915 Estrogen signaling pathway
    805 (CALM2)
   04921 Oxytocin signaling pathway
    805 (CALM2)
   04916 Melanogenesis
    805 (CALM2)
   04924 Renin secretion
    805 (CALM2)
   04925 Aldosterone synthesis and secretion
    805 (CALM2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    805 (CALM2)
   04270 Vascular smooth muscle contraction
    805 (CALM2)
  09154 Digestive system
   04970 Salivary secretion
    805 (CALM2)
   04971 Gastric acid secretion
    805 (CALM2)
  09156 Nervous system
   04728 Dopaminergic synapse
    805 (CALM2)
   04720 Long-term potentiation
    805 (CALM2)
   04722 Neurotrophin signaling pathway
    805 (CALM2)
  09157 Sensory system
   04744 Phototransduction
    805 (CALM2)
   04740 Olfactory transduction
    805 (CALM2)
   04750 Inflammatory mediator regulation of TRP channels
    805 (CALM2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    805 (CALM2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    805 (CALM2)
  09162 Cancer: specific types
   05214 Glioma
    805 (CALM2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    805 (CALM2)
  09165 Substance dependence
   05031 Amphetamine addiction
    805 (CALM2)
   05034 Alcoholism
    805 (CALM2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    805 (CALM2)
  09171 Infectious disease: bacterial
   05133 Pertussis
    805 (CALM2)
   05152 Tuberculosis
    805 (CALM2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    805 (CALM2)
   05163 Human cytomegalovirus infection
    805 (CALM2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    805 (CALM2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    805 (CALM2)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    805 (CALM2)
   03036 Chromosome and associated proteins [BR:hsa03036]
    805 (CALM2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    805 (CALM2)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     805 (CALM2)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    805 (CALM2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Centriole replication proteins
     805 (CALM2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   805 (CALM2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EF-hand_1 EF-hand_7 EF-hand_8 EF-hand_6 EF-hand_5 EF-hand_9 EF-hand_4 SPARC_Ca_bdg EF-hand_11 UPF0154 EFhand_Ca_insen Dockerin_1 DUF1103 Caleosin DUF4497 TerB DUF5580 SurA_N_2 Poly_export DUF2267 SurA_N_3 Fe_hyd_lg_C MotA_activ
Motif
Other DBs
NCBI-GeneID: 805
NCBI-ProteinID: NP_001734
OMIM: 114182
HGNC: 1445
Ensembl: ENSG00000143933
Vega: OTTHUMG00000128850
UniProt: P0DP23 P0DP24 P0DP25 B4DJ51
LinkDB All DBs
Structure
PDB: 

Position
2p21
AA seq 149 aa AA seqDB search
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
EVDEMIREADIDGDGQVNYEEFVQMMTAK
NT seq 450 nt NT seq  +upstreamnt  +downstreamnt
atggctgaccaactgactgaagagcagattgcagaattcaaagaagctttttcactattt
gacaaagatggtgatggaactataacaacaaaggaattgggaactgtaatgagatctctt
gggcagaatcccacagaagcagagttacaggacatgattaatgaagtagatgctgatggt
aatggcacaattgacttccctgaatttctgacaatgatggcaagaaaaatgaaagacaca
gacagtgaagaagaaattagagaagcattccgtgtgtttgataaggatggcaatggctat
attagtgctgcagaacttcgccatgtgatgacaaaccttggagagaagttaacagatgaa
gaagttgatgaaatgatcagggaagcagatattgatggtgatggtcaagtaaactatgaa
gagtttgtacaaatgatgacagcaaagtga

KEGG   Homo sapiens (human): 808Help
Entry
808               CDS       T01001                                 

Gene name
CALM3, CALM, CAM1, CAM2, CAMB, CaM, CaMIII, HEL-S-72, PHKD, PHKD3
Definition
(RefSeq) calmodulin 3
  KO
K02183  calmodulin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04070  Phosphatidylinositol signaling system
hsa04114  Oocyte meiosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04371  Apelin signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04713  Circadian entrainment
hsa04720  Long-term potentiation
hsa04722  Neurotrophin signaling pathway
hsa04728  Dopaminergic synapse
hsa04740  Olfactory transduction
hsa04744  Phototransduction
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04910  Insulin signaling pathway
hsa04912  GnRH signaling pathway
hsa04915  Estrogen signaling pathway
hsa04916  Melanogenesis
hsa04921  Oxytocin signaling pathway
hsa04922  Glucagon signaling pathway
hsa04924  Renin secretion
hsa04925  Aldosterone synthesis and secretion
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa05010  Alzheimer disease
hsa05031  Amphetamine addiction
hsa05034  Alcoholism
hsa05133  Pertussis
hsa05152  Tuberculosis
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
hsa05214  Glioma
hsa05418  Fluid shear stress and atherosclerosis
Network
nt06120  Calcium signaling (virus)
nt06124  Chemokine signaling (virus)
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165  Epstein-Barr virus (EBV)
nt06167  Human cytomegalovirus (HCMV)
nt06220  Calcium signaling
nt06273  Glioma
nt06316  Angiotensin-aldosterone signaling
  Element
N00026  EGF-EGFR-PLCG-CAMK signaling pathway
N00027  Amplified EGFR to PLCG-CAMK signaling pathway
N00028  PDGF-PDGFR-PLCG-CAMK signaling pathway
N00029  Amplified PDGFR to PLCG-CAMK signaling pathway
N00147  EGF-EGFR-PLCG-calcineurin signaling pathway
N00172  KSHV K15 to PLCG-calcineurin signaling pathway
N00180  KSHV K1 to PLCG-calcineurin signaling pathway
N00301  Angiotensin-aldosterone signaling pathway
N00302  Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303  Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304  Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305  Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N00401  CXCR4-GNAQ-PLCB/G-calcineurin signaling pathway
N00402  HCMV US28 to GNAQ-PLCB/G-calcineurin signaling pathway
N00432  HIV gp120 to CXCR4-GNAQ-PLCB/G-calcineurin
N00487  BCR-PLCG-Calcineurin signaling pathway
N00490  HTLV-1 p12 to calcineurin signaling pathway
Drug target
Lubeluzole: D04789
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    808 (CALM3)
   04015 Rap1 signaling pathway
    808 (CALM3)
   04371 Apelin signaling pathway
    808 (CALM3)
   04020 Calcium signaling pathway
    808 (CALM3)
   04070 Phosphatidylinositol signaling system
    808 (CALM3)
   04024 cAMP signaling pathway
    808 (CALM3)
   04022 cGMP-PKG signaling pathway
    808 (CALM3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    808 (CALM3)
   04218 Cellular senescence
    808 (CALM3)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    808 (CALM3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    808 (CALM3)
   04922 Glucagon signaling pathway
    808 (CALM3)
   04912 GnRH signaling pathway
    808 (CALM3)
   04915 Estrogen signaling pathway
    808 (CALM3)
   04921 Oxytocin signaling pathway
    808 (CALM3)
   04916 Melanogenesis
    808 (CALM3)
   04924 Renin secretion
    808 (CALM3)
   04925 Aldosterone synthesis and secretion
    808 (CALM3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    808 (CALM3)
   04270 Vascular smooth muscle contraction
    808 (CALM3)
  09154 Digestive system
   04970 Salivary secretion
    808 (CALM3)
   04971 Gastric acid secretion
    808 (CALM3)
  09156 Nervous system
   04728 Dopaminergic synapse
    808 (CALM3)
   04720 Long-term potentiation
    808 (CALM3)
   04722 Neurotrophin signaling pathway
    808 (CALM3)
  09157 Sensory system
   04744 Phototransduction
    808 (CALM3)
   04740 Olfactory transduction
    808 (CALM3)
   04750 Inflammatory mediator regulation of TRP channels
    808 (CALM3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    808 (CALM3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    808 (CALM3)
  09162 Cancer: specific types
   05214 Glioma
    808 (CALM3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    808 (CALM3)
  09165 Substance dependence
   05031 Amphetamine addiction
    808 (CALM3)
   05034 Alcoholism
    808 (CALM3)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    808 (CALM3)
  09171 Infectious disease: bacterial
   05133 Pertussis
    808 (CALM3)
   05152 Tuberculosis
    808 (CALM3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    808 (CALM3)
   05163 Human cytomegalovirus infection
    808 (CALM3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    808 (CALM3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    808 (CALM3)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    808 (CALM3)
   03036 Chromosome and associated proteins [BR:hsa03036]
    808 (CALM3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    808 (CALM3)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     808 (CALM3)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    808 (CALM3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Centriole replication proteins
     808 (CALM3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   808 (CALM3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EF-hand_1 EF-hand_7 EF-hand_8 EF-hand_6 EF-hand_5 EF-hand_9 EF-hand_4 SPARC_Ca_bdg EF-hand_11 UPF0154 EFhand_Ca_insen Dockerin_1 DUF1103 Caleosin DUF4497 TerB DUF5580 SurA_N_2 Poly_export DUF2267 SurA_N_3 Fe_hyd_lg_C MotA_activ
Motif
Other DBs
NCBI-GeneID: 808
NCBI-ProteinID: NP_001316851
OMIM: 114183
HGNC: 1449
Ensembl: ENSG00000160014
Vega: OTTHUMG00000133517
Pharos: P62158(Tclin)
UniProt: P0DP23 P0DP24 P0DP25 B4DJ51
LinkDB All DBs
Structure
PDB: 

Position
19q13.32
AA seq 149 aa AA seqDB search
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
EVDEMIREADIDGDGQVNYEEFVQMMTAK
NT seq 450 nt NT seq  +upstreamnt  +downstreamnt
atggctgaccagctgactgaggagcagattgcagagttcaaggaggccttctccctcttt
gacaaggatggagatggcactatcaccaccaaggagttggggacagtgatgagatccctg
ggacagaaccccactgaagcagagctgcaggatatgatcaatgaggtggatgcagatggg
aacgggaccattgacttcccggagttcctgaccatgatggccagaaagatgaaggacaca
gacagtgaggaggagatccgagaggcgttccgtgtctttgacaaggatgggaatggctac
atcagcgccgcagagctgcgtcacgtaatgacgaacctgggggagaagctgaccgatgag
gaggtggatgagatgatcagggaggctgacatcgatggagatggccaggtcaattatgaa
gagtttgtacagatgatgactgcaaagtga

KEGG   Homo sapiens (human): 810Help
Entry
810               CDS       T01001                                 

Gene name
CALML3, CLP
Definition
(RefSeq) calmodulin like 3
  KO
K02183  calmodulin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04070  Phosphatidylinositol signaling system
hsa04114  Oocyte meiosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04371  Apelin signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04713  Circadian entrainment
hsa04720  Long-term potentiation
hsa04722  Neurotrophin signaling pathway
hsa04728  Dopaminergic synapse
hsa04740  Olfactory transduction
hsa04744  Phototransduction
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04910  Insulin signaling pathway
hsa04912  GnRH signaling pathway
hsa04915  Estrogen signaling pathway
hsa04916  Melanogenesis
hsa04921  Oxytocin signaling pathway
hsa04922  Glucagon signaling pathway
hsa04924  Renin secretion
hsa04925  Aldosterone synthesis and secretion
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa05010  Alzheimer disease
hsa05031  Amphetamine addiction
hsa05034  Alcoholism
hsa05133  Pertussis
hsa05152  Tuberculosis
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
hsa05214  Glioma
hsa05418  Fluid shear stress and atherosclerosis
Drug target
Lubeluzole: D04789
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    810 (CALML3)
   04015 Rap1 signaling pathway
    810 (CALML3)
   04371 Apelin signaling pathway
    810 (CALML3)
   04020 Calcium signaling pathway
    810 (CALML3)
   04070 Phosphatidylinositol signaling system
    810 (CALML3)
   04024 cAMP signaling pathway
    810 (CALML3)
   04022 cGMP-PKG signaling pathway
    810 (CALML3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    810 (CALML3)
   04218 Cellular senescence
    810 (CALML3)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    810 (CALML3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    810 (CALML3)
   04922 Glucagon signaling pathway
    810 (CALML3)
   04912 GnRH signaling pathway
    810 (CALML3)
   04915 Estrogen signaling pathway
    810 (CALML3)
   04921 Oxytocin signaling pathway
    810 (CALML3)
   04916 Melanogenesis
    810 (CALML3)
   04924 Renin secretion
    810 (CALML3)
   04925 Aldosterone synthesis and secretion
    810 (CALML3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    810 (CALML3)
   04270 Vascular smooth muscle contraction
    810 (CALML3)
  09154 Digestive system
   04970 Salivary secretion
    810 (CALML3)
   04971 Gastric acid secretion
    810 (CALML3)
  09156 Nervous system
   04728 Dopaminergic synapse
    810 (CALML3)
   04720 Long-term potentiation
    810 (CALML3)
   04722 Neurotrophin signaling pathway
    810 (CALML3)
  09157 Sensory system
   04744 Phototransduction
    810 (CALML3)
   04740 Olfactory transduction
    810 (CALML3)
   04750 Inflammatory mediator regulation of TRP channels
    810 (CALML3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    810 (CALML3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    810 (CALML3)
  09162 Cancer: specific types
   05214 Glioma
    810 (CALML3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    810 (CALML3)
  09165 Substance dependence
   05031 Amphetamine addiction
    810 (CALML3)
   05034 Alcoholism
    810 (CALML3)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    810 (CALML3)
  09171 Infectious disease: bacterial
   05133 Pertussis
    810 (CALML3)
   05152 Tuberculosis
    810 (CALML3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    810 (CALML3)
   05163 Human cytomegalovirus infection
    810 (CALML3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    810 (CALML3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    810 (CALML3)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    810 (CALML3)
   03036 Chromosome and associated proteins [BR:hsa03036]
    810 (CALML3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    810 (CALML3)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     810 (CALML3)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    810 (CALML3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Centriole replication proteins
     810 (CALML3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   810 (CALML3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EF-hand_1 EF-hand_7 EF-hand_8 EF-hand_6 EF-hand_5 EF-hand_9 EF-hand_4 SPARC_Ca_bdg UPF0154 EFhand_Ca_insen TerB Dockerin_1 EF-hand_11 Caleosin dCache_2 DUF5580 DUF1103 SurA_N_2 Spore_III_AB Fe_hyd_lg_C SurA_N_3 sCache_2
Motif
Other DBs
NCBI-GeneID: 810
NCBI-ProteinID: NP_005176
OMIM: 114184
HGNC: 1452
Ensembl: ENSG00000178363
Vega: OTTHUMG00000017597
Pharos: P27482(Tbio)
UniProt: P27482
LinkDB All DBs
Structure
PDB: 

Position
10p15.1
AA seq 149 aa AA seqDB search
MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDG
NGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDE
EVDEMIRAADTDGDGQVNYEEFVRVLVSK
NT seq 450 nt NT seq  +upstreamnt  +downstreamnt
atggccgaccagctgactgaggagcaggtcacagaattcaaggaggccttctccctgttt
gacaaggatggggacggctgcatcaccacccgcgagctgggcacggtcatgcggtccctg
ggccagaaccccacggaggccgagctgcgggacatgatgagtgagatcgaccgggacggc
aacggcaccgtggacttccccgagttcctgggcatgatggccaggaagatgaaggacacg
gacaacgaggaggagatccgcgaggccttccgcgtgttcgacaaggacggcaacggcttc
gtcagcgccgccgagctgcgacacgtcatgacccggctgggggagaagctgagtgacgag
gaggtggacgagatgatccgggccgcggacacggacggagacggacaggtgaactacgag
gagtttgtccgtgtgctggtgtccaagtga

KEGG   Homo sapiens (human): 91860Help
Entry
91860             CDS       T01001                                 

Gene name
CALML4, NY-BR-20
Definition
(RefSeq) calmodulin like 4
  KO
K02183  calmodulin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04070  Phosphatidylinositol signaling system
hsa04114  Oocyte meiosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04371  Apelin signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04713  Circadian entrainment
hsa04720  Long-term potentiation
hsa04722  Neurotrophin signaling pathway
hsa04728  Dopaminergic synapse
hsa04740  Olfactory transduction
hsa04744  Phototransduction
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04910  Insulin signaling pathway
hsa04912  GnRH signaling pathway
hsa04915  Estrogen signaling pathway
hsa04916  Melanogenesis
hsa04921  Oxytocin signaling pathway
hsa04922  Glucagon signaling pathway
hsa04924  Renin secretion
hsa04925  Aldosterone synthesis and secretion
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa05010  Alzheimer disease
hsa05031  Amphetamine addiction
hsa05034  Alcoholism
hsa05133  Pertussis
hsa05152  Tuberculosis
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
hsa05214  Glioma
hsa05418  Fluid shear stress and atherosclerosis
Drug target
Lubeluzole: D04789
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    91860 (CALML4)
   04015 Rap1 signaling pathway
    91860 (CALML4)
   04371 Apelin signaling pathway
    91860 (CALML4)
   04020 Calcium signaling pathway
    91860 (CALML4)
   04070 Phosphatidylinositol signaling system
    91860 (CALML4)
   04024 cAMP signaling pathway
    91860 (CALML4)
   04022 cGMP-PKG signaling pathway
    91860 (CALML4)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    91860 (CALML4)
   04218 Cellular senescence
    91860 (CALML4)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    91860 (CALML4)
  09152 Endocrine system
   04910 Insulin signaling pathway
    91860 (CALML4)
   04922 Glucagon signaling pathway
    91860 (CALML4)
   04912 GnRH signaling pathway
    91860 (CALML4)
   04915 Estrogen signaling pathway
    91860 (CALML4)
   04921 Oxytocin signaling pathway
    91860 (CALML4)
   04916 Melanogenesis
    91860 (CALML4)
   04924 Renin secretion
    91860 (CALML4)
   04925 Aldosterone synthesis and secretion
    91860 (CALML4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    91860 (CALML4)
   04270 Vascular smooth muscle contraction
    91860 (CALML4)
  09154 Digestive system
   04970 Salivary secretion
    91860 (CALML4)
   04971 Gastric acid secretion
    91860 (CALML4)
  09156 Nervous system
   04728 Dopaminergic synapse
    91860 (CALML4)
   04720 Long-term potentiation
    91860 (CALML4)
   04722 Neurotrophin signaling pathway
    91860 (CALML4)
  09157 Sensory system
   04744 Phototransduction
    91860 (CALML4)
   04740 Olfactory transduction
    91860 (CALML4)
   04750 Inflammatory mediator regulation of TRP channels
    91860 (CALML4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    91860 (CALML4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    91860 (CALML4)
  09162 Cancer: specific types
   05214 Glioma
    91860 (CALML4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    91860 (CALML4)
  09165 Substance dependence
   05031 Amphetamine addiction
    91860 (CALML4)
   05034 Alcoholism
    91860 (CALML4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    91860 (CALML4)
  09171 Infectious disease: bacterial
   05133 Pertussis
    91860 (CALML4)
   05152 Tuberculosis
    91860 (CALML4)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    91860 (CALML4)
   05163 Human cytomegalovirus infection
    91860 (CALML4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    91860 (CALML4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    91860 (CALML4)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    91860 (CALML4)
   03036 Chromosome and associated proteins [BR:hsa03036]
    91860 (CALML4)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    91860 (CALML4)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     91860 (CALML4)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    91860 (CALML4)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Centriole replication proteins
     91860 (CALML4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   91860 (CALML4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EF-hand_7 EF-hand_8 EF-hand_1 EF-hand_6 EF-hand_9 EF-hand_4 EF-hand_11 FlgD
Motif
Other DBs
NCBI-GeneID: 91860
NCBI-ProteinID: NP_219501
HGNC: 18445
Ensembl: ENSG00000129007
Vega: OTTHUMG00000133287
Pharos: Q96GE6(Tdark)
UniProt: Q96GE6
LinkDB All DBs
Position
15q23
AA seq 196 aa AA seqDB search
MAAEHLLPGPPPSLADFRLEAGGKGTERGSGSSKPTGSSRGPRMAKFLSQDQINEYKECF
SLYDKQQRGKIKATDLMVAMRCLGASPTPGEVQRHLQTHGIDGNGELDFSTFLTIMHMQI
KQEDPKKEILLAMLMVDKEKKGYVMASDLRSKLTSLGEKLTHKEVDDLFREADIEPNGKV
KYDEFIHKITLPGRDY
NT seq 591 nt NT seq  +upstreamnt  +downstreamnt
atggcagccgagcatttattacccgggcctccacccagcttggcagactttagacttgag
gctggaggaaagggaactgaacgcggttctgggagcagcaagcccacgggtagcagccga
ggccccagaatggccaagtttctttcccaagaccaaattaatgagtacaaggaatgcttc
tccctgtatgacaagcagcagagggggaagataaaagccaccgacctcatggtggccatg
aggtgcctgggggccagcccgacgccaggggaggtgcagcggcacctgcagacccacggg
atagacggaaatggagagctggatttctccacttttctgaccattatgcacatgcaaata
aaacaagaagacccaaagaaagaaattcttctagccatgttgatggtggacaaggagaag
aaaggttacgtcatggcgtccgacctgcggtcaaaactcacgagtctgggggagaagctc
acccacaaggaagtggatgatctcttcagggaagcagatatcgaacccaatggcaaagtg
aagtatgatgaatttatccacaagatcacccttcctggacgggactattga

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