KEGG   Homo sapiens (human): 1770
Entry
1770              CDS       T01001                                 

Gene name
DNAH9, CILD40, DNAH17L, DNEL1, DYH9, Dnahc9, HL-20, HL20
Definition
(RefSeq) dynein axonemal heavy chain 9
  KO
K10408  dynein heavy chain, axonemal
Organism
hsa  Homo sapiens (human)
Pathway
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05022  Pathways of neurodegeneration - multiple diseases
Network
nt06419  Microtubule-based transport
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N01159  Mutation-caused aberrant TUBA4A to retrograde axonal transport
N01160  Mutation-caused aberrant SOD1 to retrograde axonal transport
Disease
H00564  Primary ciliary dyskinesia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    1770 (DNAH9)
   05016 Huntington disease
    1770 (DNAH9)
   05022 Pathways of neurodegeneration - multiple diseases
    1770 (DNAH9)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1770 (DNAH9)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1770 (DNAH9)
SSDB
Motif
Pfam: MT DHC_N1 AAA_6 DHC_N2 AAA_8 Dynein_C AAA_9 AAA_7 AAA_lid_11 AAA_lid_1 Dynein_heavy Dynein_AAA_lid AAA_5 AAA_16 AAA_30 Sigma54_activat AAA_19
Other DBs
NCBI-GeneID: 1770
NCBI-ProteinID: NP_001363
OMIM: 603330
HGNC: 2953
Ensembl: ENSG00000007174
Vega: OTTHUMG00000130383
Pharos: Q9NYC9(Tbio)
UniProt: Q9NYC9
LinkDB
Position
17p12
AA seq 4486 aa
MRLAEERAALAAENADGEPGADRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFL
GRDAAEGPRPLLVVRPGPRGLAIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAV
VCGDLPAAPLEHLAALFSEVVLPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQV
KGKTLLPLPAGSEKMEFADSKSETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPL
LQGENPTPKVELEFWKSRYEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVV
AALAEAQDIHVHLIPLQRHLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTV
LLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFK
ENQEVKEWDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQ
QMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGL
EHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPV
HKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYET
RLYEDWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPE
TAAAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLN
WKTEGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVTPIFKTKDGKRESLLSLD
DRHDRMEKYYNLIKESGLKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIE
CSLKYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIP
SLVPRLSPQNGSPHYQVDLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVED
RKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKV
FDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKG
DFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNN
IKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDA
RHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWE
TTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPA
IRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKEL
QTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQK
KLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKI
PNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGT
APQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWL
NHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEE
GYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDN
AQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSL
HLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC
FDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRT
ELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHY
DWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPA
LDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQV
LRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDG
PKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVS
RAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIP
EQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSK
WWLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRV
CYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVL
EKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLS
LKEITNVQYVSCMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNF
PASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKST
WDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFA
NGIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGN
ALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVF
LMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKF
FIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNT
EGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRK
ELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSR
EKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGS
PPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKA
IRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQ
EKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENV
RWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVT
PALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKY
GEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGD
KECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQ
LKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQE
AKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPD
ESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRS
PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQ
EWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMF
FILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQN
IHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPT
GMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNT
GDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEML
EGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVL
ELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAKVEERTPYIVVAFQECG
RMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAW
FPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDM
TKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQ
DCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQI
NT seq 13461 nt   +upstreamnt  +downstreamnt
atgcggctcgcggaggagcgggccgcgctcgcggcggagaacgcggatggggaacccggc
gccgaccgacgactgcgactcctggggacctacgtggccatgagcctgcggccggctgcg
ggcgcctgggagcgttgcgcggggagtgctgaggcggagcagctgctccaggccttcctg
ggccgcgatgctgccgaggggccgcggccgctgctggtggtgcggcccgggcccaggggc
ctggcaatacgccccgggctggaggtgggacctgagtcgggcctggctggcgctaaggcg
ctttttttccttcgcaccgggcccgagcctccagggcccgacagcttccgcggcgcagtg
gtctgcggggacctgcccgcggcacctctggagcacctagccgcgctgttctcggaggtt
gttctacccgtcctggccaatgagaagaatcgcctaaactggccccacatgatatgtgag
gatgtcaggcggcacgcccacagcctccaatgtgacctctcagttatacttgagcaagtg
aagggaaaaactttgctgcctcttccagcaggctcagaaaaaatggagtttgcggattcc
aaaagtgagacagtcttggattctatagataagtcagtcatctatgccattgagtctgca
gtgatcaaatggagctaccaagtccaggtggtactcaagagagagtcttcccagccactc
ttacaaggggagaatcccacccctaaggtggagttggagttctggaagagcaggtatgaa
gatctgaaatacatctataatcaactgagaacaataacggtgaggggcatggccaagctc
ctggacaagcttcagagtagctactttccagctttcaaagccatgtacagagatgttgtt
gcagctctagcagaggcacaggacatccatgtgcacctgataccgctccagcgccacctg
gaagctctggagaatgcagaatttccggaggtgaagccccagctgcggcccctgctccac
gtggtctgtctgatttgggccacatgcaagtcctaccgctccccgggaaggctgactgtg
ctgctccaggagatttgcaaccttctcatccagcaggcctctaattatctcagcccagaa
gacctgctgagaagtgaggtagaagaaagtcagagaaaactgcaagtggtctcagacact
ttgagcttcttcaagcaagagtttcaggacagaagggagaatctccacacttacttcaaa
gagaaccaggaagtcaaggaatgggatttccagtcttctttggtctttgtgcgattggat
ggcttcctgggacaactgcacgtggtggagggtcttctgaagacggccctggatttccac
aaactgggaaaggtggagttcagcggcgtcagagggaatgctctgagtcagcaggtccag
caaatgcatgaagaatttcaagagatgtacaggcttctctcaggatcctcctccgactgc
ctgtacctccaaagcacggactttgaaaatgacgtctctgaatttaaccagaaagtagaa
gatcttgaccgaagattggggactatctttattcaagcttttgatgatgcacctggcttg
gagcatgcctttaagctgctagacatagcaggaaacctccttgaaagaccgctggtagcg
agggatacatctgataaatacctggtcctcatccaaatgttcaacaaagatctggatgca
gtgaggatgatctacagtcagcacgtccaggaggaagcagaacttgggttctccccggtg
cacaagaacatgcccaccgtggctggcggcctccgctgggcacaggagctgaggcagcgc
atccagggtcctttcagcaactttggacgcatcacacacccttgcatggaatctgcagaa
ggaaagcgaatgcaacaaaaatatgaagatatgctgtcattgctagaaaagtatgagaca
agactttatgaggattggtgccggacagtatcagagaagtcacagtacaatctttcccaa
ccacttctaaaacgtgacccagagacgaaggagatcactatcaactttaacccacagctg
atttcagtgctgaaagaaatgagctatcttgaacccagagagatgaaacacatgcctgag
acagcagcagccatgttctcctccagggatttctatcggcagcttgtggctaatttagag
ttgatggcaaattggtacaacaaggttatgaaaactctgctggaggtggaatttccatta
gtggaggaagagctgcaaaatattgatctccgcctcagagcagcagaggagactttgaac
tggaaaacagaaggcatttgcgattatgtcactgaaatcaccagtagtattcatgatctt
gaacaaagaattcagaaaactaaagacaatgtggaagagatccaaaacatcatgaaaaca
tgggtgactccaatatttaagacaaaagatggaaaaagggaatcccttctttctctggat
gatcggcatgatcgaatggaaaaatattacaatctcatcaaggaatctggccttaagatc
cacgcccttgttcaggaaaacctgggtctattttcagcagacccaacctccaatatctgg
aagacttatgttaactctattgacaatttgttgctgaatggattctttcttgccattgag
tgctccctcaagtatcttctggaaaatactgagtgtaaggcaggacttaccccaatattt
gaagcacaactgagtctagccatcccagagctagttttctatccgtctctggagtctgga
gtgaaggggggtttctgtgacattgttgagggtctcatcaccagcatttttaggatacca
tctctggtgccacggctttccccacaaaatggctctcctcactatcaggtcgacctggac
ggtataccagatttggcaaacatgcggcgcacactcatggagagagtccagagaatgatg
ggcctctgctgtggctatcagagcaccttcagccagtattcgtacctctatgtggaggac
cggaaggaggttctgggtcagtttctgctgtacgggcacatcctcactccggaagaaatt
gaagaccatgtggaagatggcatcccagagaaccctcccctcctttctcagtttaaagtg
caaatcgactcctatgaaacgctctatgaagaggtgtgcaggctggaacccatcaaggtg
tttgacggctggatgaaaattgatattcgaccctttaaggcatctctgctgaatattatt
aagaggtggagcctcctgttcaaacagcatcttgtggaccacgtcactcacagcttggcc
aacctggatgcgtttataaagaagagtgagagcggcttactcaagaaagttgaaaaagga
gatttccaaggcttggttgagatcatgggacaccttatggctgttaaagaacggcagagt
aacactgatgagatgtttgagcccttaaagcagactattgaattgctgaagacctatgaa
caagaattgccagaaacagtgtttaagcagctggaggagctgcctgagaaatggaacaac
ataaaaaaggtggccattactgtgaagcagcaggtggccccactgcaggcaaatgaagtg
acactcctccgccagaggtgcacagccttcgatgcagaacagcagcaattctgggagcaa
ttccacaaagaagccccgttcaggtttgatagcatccaccctcatcaaatgctggatgcc
aggcacatcgagatccagcagatggaatccactatggcctccatttctgagtctgccagc
ttatttgaagtcaatgtccctgactataagcagctgaggcagtgcaggaaggaggtctgc
cagctgaaggagctctgggacaccattggaatggtgacctccagcatccatgcctgggag
accacaccctggaggaatatcaacgtggaagccatggagttggagtgcaaacagtttgcc
cggcatatccgaaacctggacaaggaggtcagggcctgggatgcattcacaggcctggaa
agcactgtgtggaacacgctgagctccctgagggcagtagctgagctgcagaatccagcc
atccgggagcggcactggaggcagctgatgcaggccaccggtgtgagcttcactatggac
caggacaccaccctagcgcacctgctgcagctccagctgcaccactatgaggatgaggtc
cggggcattgtggacaaagctgcaaaagagatgggtatggagaaaaccttaaaggagctg
cagactacctgggctggcatggaattccagtatgagccccacccacggaccaatgtcccc
ctcctgtgctctgatgaggacctcatagaggttctggaggataatcaagttcaacttcag
aacctggtgatgtccaagtatgttgctttcttcttggaggaggtgtcgggctggcagaag
aagctgtccacagtggacgctgtcatctctatctggtttgaagtgcagcgaacatggact
cacctggaaagcatattcactggatctgaagatattcgggcacagctaccccaggattct
aaaaggtttgaaggcatcgacattgactttaaagagctagcttatgatgcccagaaaatt
ccaaatgtagtgcaaaccaccaacaagccaggcctgtatgaaaagctggaggatattcag
ggcagattgtgcctgtgtgagaaggccctggcagagtacctcgacaccaagaggcttgcc
ttcccgcggttttactttctctcctcctccgatctgttagacatcctttccaacggcaca
gctccacaacaggttcaacgtcacctttccaaactctttgacaacatggccaagatgcga
ttccagctagatgccagtggggaaccaaccaagacaagcctcggcatgtacagcaaagaa
gaggagtatgtggctttcagtgagccctgtgactgcagcgggcaggtagaaatatggctg
aaccatgtccttggtcacatgaaggccactgtgaggcatgagatgacagaaggtgtaact
gcctatgaagaaaagccgagggagcagtggctttttgaccacccagctcaggtggccctg
acctgtactcagatctggtggacaacagaagtgggcatggcatttgccaggctggaggaa
ggctatgagagtgccatgaaggactattataagaagcaagtggcccagctcaaaaccctt
atcaccatgctgattggccagctctccaagggagaccggcagaagattatgactatatgc
accatcgatgtgcatgcccgggatgtggtagccaagatgattgctcagaaggtagacaat
gcccaggctttcctctggctgtctcagctgcgccatcgttgggatgacgaggtcaaacac
tgctttgccaacatctgtgatgcccagtttttgtattcctatgagtacctgggaaacaca
cctcgcttggtgatcacacctttgactgacaggtgctacatcaccctcacccagtccctg
cacctgaccatgagtggggctcccgcaggacctgcaggcacaggcaagaccgagaccacc
aaggacctgggccgcgcactgggcatcctggtctatgtgttcaactgctcggagcagatg
gattacaagtcttgtggcaacatctacaaaggccttgctcagactggtgcctggggctgc
tttgatgagtttaatcgaatctccgtggaggtcttgtcagtggtggcagtgcaggtaaaa
agcattcaagatgcgattagagataagaagcagtggttcagcttccttggggaggagatc
agcctgaatccttctgtcggtatcttcatcaccatgaacccaggctatgctggccgcaca
gagctgccagagaatctcaagtctctcttcaggccttgtgcaatggtggttccagacttt
gaattgatctgtgaaatcatgctggtggcagaaggattcattgaagcccagtcattagcc
agaaagttcatcactctttaccagttgtgcaaagagcttctctccaaacaggatcactac
gactggggcctacgggccatcaagtccgtgctggtggtggcaggatccctgaagagagga
gaccctgaccggcctgaggaccaggtcctgatgcgctccttgcgggatttcaacatcccc
aagattgtgactgatgacatgcccatcttcatgggcctgatcggggacctctttcccgcc
ctggatgtcccccggaggagagaccccaacttcgaagctttggttaggaaggcgatagtg
gatctgaagctccaggctgaggacaactttgtgctcaaggtggtccagctggaggagctc
ctggctgtgcggcactctgtatttgtggtgggtggcgctggtaccggcaagtcacaggtg
ctgaggtccttgcacaagacctatcagatcatgaaacggcgccccgtctggactgacctc
aatcccaaagcagtcacaaatgatgagctctttggcatcatcaatccagccacaggagaa
tggaaggatggattgttctcttccatcatgcgggagcttgccaacatcacccatgatggg
cccaagtggattttactggatggcgacatagatccaatgtggattgaatccctgaatact
gtcatggatgataacaaggtgctgacattggccagcaatgagaggattcctctgaacccc
accatgaagctcctctttgagatcagccacctgcgcacagccactccagcaactgtctct
agagcagggatcttgtacatcaacccggcagacttgggatggaaccctccagtgagcagc
tggattgagaagagggaaatccagacagagagagccaacttaaccattttgttcgacaag
tatcttccaacctgcctagacacactcagaaccaggtttaagaagatcattcccatccca
gagcagagcatggttcagatggtgtgtcaccttctggaatgtctcctgaccacggaggac
atccctgcagactgccctaaggaaatttatgagcattattttgtgtttgctgccatctgg
gctttcggcggagcaatggtccaagatcagcttgtggactaccgggcagagttcagcaaa
tggtggctgactgagttcaaaacagtcaagtttccttcccaaggaaccatctttgactat
tacatcgacccagagaccaagaaattcgagccttggtccaagctcgtcccccagttcgaa
tttgaccccgagatgcccttgcaggcgtgtttggtgcacacgagtgagaccatccgtgtg
tgctacttcatggagcggttgatggcgcggcagcggcctgtcatgctggtgggcacggct
ggcactggcaagtcggtgctggtgggagctaagctggccagccttgaccccgaggcatac
ctggtgaaaaacgtgccattcaactactacaccacgtcagcaatgctgcaggctgtcctg
gagaagcctctggaaaagaaggctggcagaaactatggccctccagggaacaagaaactc
atctatttcattgatgacatgaacatgcctgaggtggatgcctacgggacggtgcagccc
cacaccatcatccggcagcatctggactatggccactggtatgatcggagcaagctgtcc
ctaaaggagatcacaaatgtacagtatgtttcctgtatgaaccccacggcaggcagcttc
accatcaacccccggcttcagcgtcacttcagcgtgtttgtcctctccttcccgggggca
gatgccctgtcctctatctacagcatcatcctcactcagcatctgaagctcggaaacttc
ccggcgtccctgcagaaatccatccccccactgatcgatctggccctcgccttccaccag
aaaattgctaccaccttcctacccacaggaatcaaattccactacatcttcaacctcaga
gattttgccaacattttccagggcattctcttctcctcagtggaatgtgtgaaatccaca
tgggatcttataaggctctatctgcatgaatcaaatcgagtttatcgggataagatggta
gaagaaaaggactttgatctttttgataaaatccagacagaagtgctcaagaaaactttt
gatgatattgaagaccctgtggagcagacccaaagcccgaacctgtattgtcactttgca
aatggtattggggagcccaaatacatgcctgtacagtcttgggaacttttgacccagact
ctggtggaggccttggagaaccacaatgaagtcaacacagtgatggacctagttctcttt
gaggatgccatgcgccatgtctgccatatcaatcgcatcttggagtccccgcggggaaat
gctctgctggttggtgtaggtgggagcggcaagcagagcctgacaaggctggcagctttc
atcagctccatggatgtcttccagatcacactgcgcaaaggctaccagatccaggacttc
aagatggacctggccagcctgtgtctgaaagctggagtgaagaatctcaacacagtgttt
ctcatgactgatgcccaagtggctgatgagaggttccttgtgctcatcaatgatcttttg
gcatctggggagatcccagatctctactctgatgatgaagttgaaaacatcataagcaat
gtgaggaatgaagtcaagagccagggtctggttgacaacagagagaactgttggaagttc
tttatagatcggatccggcgacagctgaaggtgactctctgtttctcccctgtgggaaac
aagctaagagtccgcagcaggaagttcccagccattgtgaactgcacagccatccactgg
ttccacgagtggcctcagcaagcattggagtctgtcagcctccgcttcttgcagaacaca
gagggcattgagcccacagtaaagcagtcgattagcaaattcatggcctttgtccacaca
agtgtcaaccaaacatcccagtcttatctgagcaatgaacagcgctacaactatacaact
cccaagtcctttctggagttcatcagactctaccagagcttgttgcacaggcacagaaaa
gagctcaagtgcaagacagagcggttggagaacgggctgctgaagctgcatagcacctct
gcccaggtggatgatctgaaagcaaagctggctgcccaggaagtagagctgaagcagaaa
aatgaagatgcagacaaactgattcaggtcgtgggtgtggagactgacaaagtgagcaga
gagaaagccatggcagatgaagaggagcagaaggtggccgtcatcatgctagaggtgaaa
cagaagcagaaggactgtgaggaggacctggcaaaggctgagccagcactcacagcagcg
caggcagctctcaacaccctgaacaagaccaacctgacagagctgaagtcatttggctct
ccgcctctggccgtcagcaatgtcagcgctgcggtgatggtactgatggctcccaggggt
agggtgcccaaggaccggagctggaaggctgctaaggtcaccatggccaaagtggatggc
ttcctggactcgctaataaacttcaacaaagagaacattcacgagaactgcctcaaagcc
atcaggccgtatctgcaagaccccgagttcaatcctgagtttgtggccaccaaatcctat
gcggctgcaggcctctgctcctgggtcatcaatattgtgagattttatgaggtgttctgt
gatgtggaacccaagcgccaggcactgaacaaagccaccgcggacctcacagctgcccag
gagaagctggctgccatcaaagccaagatcgctcaccttaatgaaaacctggcaaagctc
acagccaggtttgagaaagcaacagcagacaaactcaaatgtcagcaagaagccgaagtg
accgcagtcaccatctcccttgccaaccgcctggttggaggactcgcttctgaaaacgtg
aggtgggcagatgccgtgcagaacttcaaacagcaggaaaggacgttatgtggagacatt
ttacttataacggctttcatttcctaccttggcttcttcacaaagaaataccggcagagc
ctcctggacagaacttggaggccctacctgagccagctgaaaactcccattccagtcacc
ccagccctggatcccctgaggatgctgatggatgatgctgacgtggctgcctggcagaac
gagggcctcccagccgaccgcatgtccgtggagaatgccaccattctcatcaactgtgag
cgctggccactcatggttgaccctcagctacaaggcatcaaatggatcaagaataaatat
ggtgaagatctccgggtcacgcagattggtcagaaaggctaccttcaaatcatagagcag
gccctggaagctggagctgtggtgctgattgaaaatctagaggagtccattgatcctgtt
ctgggacccctgcttgggagagaagtcattaaaaaaggacgattcattaaaattggagac
aaagaatgtgaatacaatcccaagttccggctcatcctccacaccaagctggctaatcct
cactaccagcctgagctgcaggctcaggccaccctgatcaacttcaccgtgaccagggat
ggcctggaggaccagttgctggccgctgtggtcagcatggagaggccagacttggagcag
ctgaagtccgatctcacaaagcagcagaatggattcaaaattaccctgaaaacgttggaa
gacagtcttctctctcgcctctcctccgcctctgggaacttcctgggagaaacagtgctg
gtggaaaacctagagatcaccaagcagactgctgccgaagttgagaaaaaggtccaggag
gccaaggtgactgaagtgaaaatcaacgaggcccgagagcactaccggccagcagctgcc
agggcctcactgctctacttcatcatgaacgacctcagcaagatccatccaatgtaccag
ttttctctcaaggccttcagtatcgtcttccagaaggctgtggagagggctgctcctgac
gaaagcctcagggagcgggtggccaacctaatagacagcataaccttctctgtgtaccag
tacaccatccgcgggctctttgagtgtgataagctgacctaccttgcccagctcaccttt
cagattctcctcatgaaccgagaagtcaatgcagtggagttggatttcctgcttcgatct
ccagtgcagacgggcaccgccagccccgtggagttcctctcccatcaggcgtggggagct
gtcaaggtactttcatcaatggaagaattctctaatctggatcgggacatagagggatct
gctaagagctggaaaaagtttgtggagtccgaatgtcctgagaaagagaagctcccacag
gagtggaagaacaagacagccctgcagcgcctctgcatgctgagagccatgcggcccgac
cggatgacctatgctttgcgagattttgttgaagagaagttaggaagcaaatacgtggtg
ggaagagccctagattttgcaacctcatttgaagaatcgggaccagccactcctatgttt
ttcatcctgtctccaggggtggacccactgaaggatgtagaaagtcaaggaagaaaactt
ggatacaccttcaacaatcagaactttcacaacgtgtctttggggcaaggacaggaagtg
gtggctgaggctgcgctggacctcgctgccaagaaaggtcactgggttattttgcagaac
attcacctggtggccaagtggctcagcaccctggagaagaagctggaggagcacagtgag
aacagccacccagagttcagggtcttcatgagtgcagagccagcaccctcccctgagggc
cacatcatcccccagggcatcctggagaactccattaagatcaccaatgagccccccacg
ggcatgcatgccaacctgcacaaggccctggacaacttcactcaggacactctggagatg
tgttctcgggagacggagtttaagagcatcctctttgctctttgttacttccatgcggtg
gtggcagaaagacgaaaatttgggccccagggatggaatcgctcatacccctttaacact
ggagacctcactatctctgtgaatgtcctctacaacttcctggaggccaacgcaaaggtc
ccctatgatgatttgcgctacctgtttggagagatcatgtatggaggccatatcacagat
gactgggacagaagactctgcagaacctacctgggggaattcattcgaccagaaatgtta
gaaggagaactgtctttggccccagggttcccactcccaggcaacatggactacaatggt
tatcatcagtacatcgatgctgagctgcccccagaatccccctacctctatggcctccac
ccgaacgcagagattggcttcctgacccaaacctcagaaaagctcttccgcactgtgctg
gagctgcagcctcgggacagccaggccagagacggagcgggcgccacaagagaagaaaag
gtcaaggcacttctggaagaaatattggagcgggtgacagacgagtttaacatcccagaa
ctgatggccaaagtggaggagcgcaccccttacattgtagttgccttccaggagtgtggc
cggatgaatatcctcaccagagagattcagcgctcactgagggagctggagctcggctta
aagggggagctgactatgaccagccacatggagaacttacagaatgccctgtacttcgat
atggtgccagagtcctgggctagacgagcctacccttccacagcaggcctggcagcctgg
tttccagacctcctcaacagaatcaaggagctagaggcttggacgggtgactttacaatg
ccctccactgtgtggctgacaggcttcttcaacccccagtcgttcctgactgccatcatg
cagtccacggctcgcaagaatgagtggccactggaccagatggccctgcaatgtgacatg
acgaagaagaacagagaagagtttaggagtcctcctcgggaaggggcctacatccatggc
ctcttcatggaaggtgcctgctgggacacacaggctgggatcattacagaggcaaagctg
aaggatctgacaccccctatgcctgtgatgttcatcaaggccattcctgcagataagcag
gactgccgcagtgtctattcctgtcctgtgtacaagactagtcagcggggacccacctac
gtgtggactttcaacctgaagactaaggaaaacccatccaagtgggttctggctggagta
gccttgcttctccagatttag

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