KEGG T01001: 1942

Homo sapiens (human): 1942

Entry

1942 CDS T01001

Gene name

EFNA1, B61, ECKLG, EFL1, EPLG1, LERK-1, LERK1, TNFAIP4

Definition

(RefSeq) ephrin A1

K05462

ephrin-A

Organism

hsa Homo sapiens (human)

Pathway

hsa04010

MAPK signaling pathway

hsa04014

Ras signaling pathway

hsa04015

Rap1 signaling pathway

hsa04151

PI3K-Akt signaling pathway

hsa04360

Axon guidance

hsa05206

MicroRNAs in cancer

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    1942 (EFNA1)
   04015 Rap1 signaling pathway
    1942 (EFNA1)
   04010 MAPK signaling pathway
    1942 (EFNA1)
   04151 PI3K-Akt signaling pathway
    1942 (EFNA1)
09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    1942 (EFNA1)
09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    1942 (EFNA1)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:hsa04052]
    1942 (EFNA1)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1942 (EFNA1)
Cytokines and growth factors [BR:hsa04052]
Growth factors
  Growth factors (RTK binding)
   1942 (EFNA1)
Glycosaminoglycan binding proteins [BR:hsa00536]
Heparan sulfate / Haparin
  Axon guidance molecules
   1942 (EFNA1)

SSDB

Motif

Pfam:

Ephrin

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P20827(Tbio)

UniProt:

P20827

LinkDB

Structure

PDB:

3HEI 3CZU 3MBW

Position

1q22

AA seq 205 aa
MEFLWAPLLGLCCSLAAADRHTVFWNSSNPKFRNEDYTIHVQLNDYVDIICPHYEDHSVA
DAAMEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLGKEF
KEGHSYYYISKPIHQHEDRCLRLKVTVSGKITHSPQAHDNPQEKRLAADDPEVRVLHSIG
HSAAPRLFPLAWTVLLLPLLLLQTP

NT seq 618 nt +upstreamnt +downstreamnt
atggagttcctctgggcccctctcttgggtctgtgctgcagtctggccgctgctgatcgc
cacaccgtcttctggaacagttcaaatcccaagttccggaatgaggactacaccatacat
gtgcagctgaatgactacgtggacatcatctgtccgcactatgaagatcactctgtggca
gacgctgccatggagcagtacatactgtacctggtggagcatgaggagtaccagctgtgc
cagccccagtccaaggaccaagtccgctggcagtgcaaccggcccagtgccaagcatggc
ccggagaagctgtctgagaagttccagcgcttcacacctttcaccctgggcaaggagttc
aaagaaggacacagctactactacatctccaaacccatccaccagcatgaagaccgctgc
ttgaggttgaaggtgactgtcagtggcaaaatcactcacagtcctcaggcccatgacaat
ccacaggagaagagacttgcagcagatgacccagaggtgcgggttctacatagcatcggt
cacagtgctgccccacgcctcttcccacttgcctggactgtgctgctccttccacttctg
ctgctgcaaaccccgtga

Homo sapiens (human): 1943

Entry

1943 CDS T01001

Gene name

EFNA2, ELF-1, EPLG6, HEK7-L, LERK-6, LERK6

Definition

(RefSeq) ephrin A2

K05462

ephrin-A

Organism

hsa Homo sapiens (human)

Pathway

hsa04010

MAPK signaling pathway

hsa04014

Ras signaling pathway

hsa04015

Rap1 signaling pathway

hsa04151

PI3K-Akt signaling pathway

hsa04360

Axon guidance

hsa05206

MicroRNAs in cancer

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    1943 (EFNA2)
   04015 Rap1 signaling pathway
    1943 (EFNA2)
   04010 MAPK signaling pathway
    1943 (EFNA2)
   04151 PI3K-Akt signaling pathway
    1943 (EFNA2)
09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    1943 (EFNA2)
09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    1943 (EFNA2)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:hsa04052]
    1943 (EFNA2)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1943 (EFNA2)
Cytokines and growth factors [BR:hsa04052]
Growth factors
  Growth factors (RTK binding)
   1943 (EFNA2)
Glycosaminoglycan binding proteins [BR:hsa00536]
Heparan sulfate / Haparin
  Axon guidance molecules
   1943 (EFNA2)

SSDB

Motif

Pfam:

Ephrin

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

O43921(Tbio)

UniProt:

O43921

LinkDB

Structure

PDB:

2WO3

Position

19p13.3

AA seq 213 aa
MAPAQRPLLPLLLLLLPLPPPPFARAEDAARANSDRYAVYWNRSNPRFHAGAGDDGGGYT
VEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAP
GGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEA
PEPIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS

NT seq 642 nt +upstreamnt +downstreamnt
atggcgcccgcgcagcgcccgctgctcccgctgctgctcctgctgttaccgctgccgccg
ccgcccttcgcgcgcgccgaggacgccgcccgcgccaactcggaccgctacgccgtctac
tggaaccgcagcaaccccaggttccacgcaggcgcgggggacgacggcgggggctacacg
gtggaggtgagcatcaatgactacctggacatctactgcccgcactatggggcgccgctg
ccgccggccgagcgcatggagcactacgtgctgtacatggtcaacggcgagggccacgcc
tcctgcgaccaccgccagcgcggcttcaagcgctgggagtgcaaccggcccgcggcgccc
ggggggccgctcaagttctcggagaagttccagctcttcacgcccttctccctgggcttc
gagttccggcccggccacgagtattactacatctctgccacgcctcccaatgctgtggac
cggccctgcctgcgactgaaggtgtacgtgcggccgaccaacgagaccctgtacgaggct
cctgagcccatcttcaccagcaataactcgtgtagcagcccgggcggctgccgcctcttc
ctcagcaccatccccgtgctctggaccctcctgggttcctag

Homo sapiens (human): 1944

Entry

1944 CDS T01001

Gene name

EFNA3, EFL2, EPLG3, Ehk1-L, LERK3

Definition

(RefSeq) ephrin A3

K05462

ephrin-A

Organism

hsa Homo sapiens (human)

Pathway

hsa04010

MAPK signaling pathway

hsa04014

Ras signaling pathway

hsa04015

Rap1 signaling pathway

hsa04151

PI3K-Akt signaling pathway

hsa04360

Axon guidance

hsa05206

MicroRNAs in cancer

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    1944 (EFNA3)
   04015 Rap1 signaling pathway
    1944 (EFNA3)
   04010 MAPK signaling pathway
    1944 (EFNA3)
   04151 PI3K-Akt signaling pathway
    1944 (EFNA3)
09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    1944 (EFNA3)
09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    1944 (EFNA3)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:hsa04052]
    1944 (EFNA3)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1944 (EFNA3)
Cytokines and growth factors [BR:hsa04052]
Growth factors
  Growth factors (RTK binding)
   1944 (EFNA3)
Glycosaminoglycan binding proteins [BR:hsa00536]
Heparan sulfate / Haparin
  Axon guidance molecules
   1944 (EFNA3)

SSDB

Motif

Pfam:

Ephrin FLYWCH

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P52797(Tbio)

UniProt:

P52797

LinkDB

Position

1q21.3

AA seq 238 aa
MAAAPLLLLLLLVPVPLLPLLAQGPGGALGNRHAVYWNSSNQHLRREGYTVQVNVNDYLD
IYCPHYNSSGVGPGAGPGPGGGAEQYVLYMVSRNGYRTCNASQGFKRWECNRPHAPHSPI
KFSEKFQRYSAFSLGYEFHAGHEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPT
LPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGTSPKREHLPLAVGIAFFLMTFLAS

NT seq 717 nt +upstreamnt +downstreamnt
atggcggcggctccgctgctgctgctgctgctgctcgtgcccgtgccgctgctgccgctg
ctggcccaagggcccggaggggcgctgggaaaccggcatgcggtgtactggaacagctcc
aaccagcacctgcggcgagagggctacaccgtgcaggtgaacgtgaacgactatctggat
atttactgcccgcactacaacagctcgggggtgggccccggggcgggaccggggcccgga
ggcggggcagagcagtacgtgctgtacatggtgagccgcaacggctaccgcacctgcaac
gccagccagggcttcaagcgctgggagtgcaaccggccgcacgccccgcacagccccatc
aagttctcggagaagttccagcgctacagcgccttctctctgggctacgagttccacgcc
ggccacgagtactactacatctccacgcccactcacaacctgcactggaagtgtctgagg
atgaaggtgttcgtctgctgcgcctccacatcgcactccggggagaagccggtccccact
ctcccccagttcaccatgggccccaatgtgaagatcaacgtgctggaagactttgaggga
gagaaccctcaggtgcccaagcttgagaagagcatcagcgggaccagccccaaacgggaa
cacctgcccctggccgtgggcatcgccttcttcctcatgacgttcttggcctcctag

Homo sapiens (human): 1945

Entry

1945 CDS T01001

Gene name

EFNA4, EFL4, EPLG4, LERK4

Definition

(RefSeq) ephrin A4

K05462

ephrin-A

Organism

hsa Homo sapiens (human)

Pathway

hsa04010

MAPK signaling pathway

hsa04014

Ras signaling pathway

hsa04015

Rap1 signaling pathway

hsa04151

PI3K-Akt signaling pathway

hsa04360

Axon guidance

hsa05206

MicroRNAs in cancer

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    1945 (EFNA4)
   04015 Rap1 signaling pathway
    1945 (EFNA4)
   04010 MAPK signaling pathway
    1945 (EFNA4)
   04151 PI3K-Akt signaling pathway
    1945 (EFNA4)
09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    1945 (EFNA4)
09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    1945 (EFNA4)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:hsa04052]
    1945 (EFNA4)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1945 (EFNA4)
Cytokines and growth factors [BR:hsa04052]
Growth factors
  Growth factors (RTK binding)
   1945 (EFNA4)
Glycosaminoglycan binding proteins [BR:hsa00536]
Heparan sulfate / Haparin
  Axon guidance molecules
   1945 (EFNA4)

SSDB

Motif

Pfam:

Ephrin

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P52798(Tbio)

UniProt:

P52798

LinkDB

Position

1q21.3

AA seq 201 aa
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPH
YEGPGPPEGPETFALYMVDWPGYESCQAEGPRAYKRWVCSLPFGHVQFSEKIQRFTPFSL
GFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERKSESAHPVGSPGESGTSGWRGGDT
PSPLCLLLLLLLLILRLLRIL

NT seq 606 nt +upstreamnt +downstreamnt
atgcggctgctgcccctgctgcggactgtcctctgggccgcgttcctcggctcccctctg
cgcgggggctccagcctccgccacgtagtctactggaactccagtaaccccaggttgctt
cgaggagacgccgtggtggagctgggcctcaacgattacctagacattgtctgcccccac
tacgaaggcccagggccccctgagggccccgagacgtttgctttgtacatggtggactgg
ccaggctatgagtcctgccaggcagagggcccccgggcctacaagcgctgggtgtgctcc
ctgccctttggccatgttcaattctcagagaagattcagcgcttcacacccttctccctc
ggctttgagttcttacctggagagacttactactacatctcggtgcccactccagagagt
tctggccagtgcttgaggctccaggtgtctgtctgctgcaaggagaggaagtctgagtca
gcccatcctgttgggagccctggagagagtggcacatcagggtggcgagggggggacact
cccagccccctctgtctcttgctattactgctgcttctgattcttcgtcttctgcgaatt
ctgtga

Homo sapiens (human): 1946

Entry

1946 CDS T01001

Gene name

EFNA5, AF1, EFL5, EPLG7, GLC1M, LERK7, RAGS

Definition

(RefSeq) ephrin A5

K05462

ephrin-A

Organism

hsa Homo sapiens (human)

Pathway

hsa04010

MAPK signaling pathway

hsa04014

Ras signaling pathway

hsa04015

Rap1 signaling pathway

hsa04151

PI3K-Akt signaling pathway

hsa04360

Axon guidance

hsa05206

MicroRNAs in cancer

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    1946 (EFNA5)
   04015 Rap1 signaling pathway
    1946 (EFNA5)
   04010 MAPK signaling pathway
    1946 (EFNA5)
   04151 PI3K-Akt signaling pathway
    1946 (EFNA5)
09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    1946 (EFNA5)
09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    1946 (EFNA5)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:hsa04052]
    1946 (EFNA5)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    1946 (EFNA5)
Cytokines and growth factors [BR:hsa04052]
Growth factors
  Growth factors (RTK binding)
   1946 (EFNA5)
Glycosaminoglycan binding proteins [BR:hsa00536]
Heparan sulfate / Haparin
  Axon guidance molecules
   1946 (EFNA5)

SSDB

Motif

Pfam:

Ephrin

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P52803(Tbio)

UniProt:

P52803

LinkDB

Structure

PDB:

4L0P 4M4R 3MX0 4BK5 2X11 4BKA

Position

5q21.3

AA seq 228 aa
MLHVEMLTLVFLVLWMCVFSQDPGSKAVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDV
FCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQL
FTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDK
VENSLEPADDTVHESAEPSRGENAAQTPRIPSRLLAILLFLLAMLLTL

NT seq 687 nt +upstreamnt +downstreamnt
atgttgcacgtggagatgttgacgctggtgtttctggtgctctggatgtgtgtgttcagc
caggacccgggctccaaggccgtcgccgaccgctacgctgtctactggaacagcagcaac
cccagattccagaggggtgactaccatattgatgtctgtatcaatgactacctggatgtt
ttctgccctcactatgaggactccgtcccagaagataagactgagcgctatgtcctctac
atggtgaactttgatggctacagtgcctgcgaccacacttccaaagggttcaagagatgg
gaatgtaaccggcctcactctccaaatggaccgctgaagttctctgaaaaattccagctc
ttcactcccttttctctaggatttgaattcaggccaggccgagaatatttctacatctcc
tctgcaatcccagataatggaagaaggtcctgtctaaagctcaaagtctttgtgagacca
acaaatagctgtatgaaaactataggtgttcatgatcgtgttttcgatgttaacgacaaa
gtagaaaattcattagaaccagcagatgacaccgtacatgagtcagccgagccatcccgc
ggcgagaacgcggcacaaacaccaaggatacccagccgccttttggcaatcctactgttc
ctcctggcgatgcttttgacattatag

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