KEGG   Homo sapiens (human): 2078
Entry
2078              CDS       T01001                                 

Gene name
ERG, erg-3, p55
Definition
(RefSeq) ETS transcription factor ERG
  KO
K09435  transcriptional regulator ERG
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
hsa05215  Prostate cancer
Network
nt06240  Transcription
nt06272  Prostate cancer
  Element
N00128  TMPRSS2-ERG fusion to transcriptional activation
N00129  TMPRSS2-ERG fusion to transcriptional repression
N00135  EWSR1-ERG fusion to transcriptional activation
Disease
H00024  Prostate cancer
H00035  Ewing sarcoma
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    2078 (ERG)
  09162 Cancer: specific types
   05215 Prostate cancer
    2078 (ERG)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    2078 (ERG)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Tryptophan clusters Ets-type
    2078 (ERG)
SSDB
Motif
Pfam: Ets SAM_PNT SAM_3 SAM_1 Arb2
Other DBs
NCBI-GeneID: 2078
NCBI-ProteinID: NP_891548
OMIM: 165080
HGNC: 3446
Ensembl: ENSG00000157554
Vega: OTTHUMG00000090767
Pharos: P11308(Tchem)
UniProt: P11308
LinkDB
Structure
PDB: 

Position
21q22.2
AA seq 479 aa
MASTIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQP
PARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPPNMTT
NERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKMTKDDFQRLT
PSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEA
TQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTS
SRLANPGSGQIQLWQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNM
NYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGS
YHAHPQKMNFVAPHPPALPVTSSSFFAAPNPYWNSPTGGIYPNTRLPTSHMPSHLGTYY
NT seq 1440 nt   +upstreamnt  +downstreamnt
atggccagcactattaaggaagccttatcagttgtgagtgaggaccagtcgttgtttgag
tgtgcctacggaacgccacacctggctaagacagagatgaccgcgtcctcctccagcgac
tatggacagacttccaagatgagcccacgcgtccctcagcaggattggctgtctcaaccc
ccagccagggtcaccatcaaaatggaatgtaaccctagccaggtgaatggctcaaggaac
tctcctgatgaatgcagtgtggccaaaggcgggaagatggtgggcagcccagacaccgtt
gggatgaactacggcagctacatggaggagaagcacatgccacccccaaacatgaccacg
aacgagcgcagagttatcgtgccagcagatcctacgctatggagtacagaccatgtgcgg
cagtggctggagtgggcggtgaaagaatatggccttccagacgtcaacatcttgttattc
cagaacatcgatgggaaggaactgtgcaagatgaccaaggacgacttccagaggctcacc
cccagctacaacgccgacatccttctctcacatctccactacctcagagagactcctctt
ccacatttgacttcagatgatgttgataaagccttacaaaactctccacggttaatgcat
gctagaaacacagggggtgcagcttttattttcccaaatacttcagtatatcctgaagct
acgcaaagaattacaactaggccagatttaccatatgagccccccaggagatcagcctgg
accggtcacggccaccccacgccccagtcgaaagctgctcaaccatctccttccacagtg
cccaaaactgaagaccagcgtcctcagttagatccttatcagattcttggaccaacaagt
agccgccttgcaaatccaggcagtggccagatccagctttggcagttcctcctggagctc
ctgtcggacagctccaactccagctgcatcacctgggaaggcaccaacggggagttcaag
atgacggatcccgacgaggtggcccggcgctggggagagcggaagagcaaacccaacatg
aactacgataagctcagccgcgccctccgttactactatgacaagaacatcatgaccaag
gtccatgggaagcgctacgcctacaagttcgacttccacgggatcgcccaggccctccag
ccccaccccccggagtcatctctgtacaagtacccctcagacctcccgtacatgggctcc
tatcacgcccacccacagaagatgaactttgtggcgccccaccctccagccctccccgtg
acatcttccagtttttttgctgccccaaacccatactggaattcaccaactgggggtata
taccccaacactaggctccccaccagccatatgccttctcatctgggcacttactactaa

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