KEGG   Homo sapiens (human): 2099Help
Entry
2099              CDS       T01001                                 

Gene name
ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1
Definition
(RefSeq) estrogen receptor 1
  KO
K08550  estrogen receptor alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa01522  Endocrine resistance
hsa04915  Estrogen signaling pathway
hsa04917  Prolactin signaling pathway
hsa04919  Thyroid hormone signaling pathway
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa05200  Pathways in cancer
hsa05205  Proteoglycans in cancer
hsa05224  Breast cancer
Network
nt06227  NR signaling
nt06270  Breast cancer
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00286  Nuclear-initiated estrogen signaling pathway
N00287  ESR1-positive to nuclear-initiated estrogen signaling pathway
N00887  Mutation-inactivated ESR1 to nuclear-initiated estrogen signaling pathway
Disease
H00031  Breast cancer
H02061  Estrogen resistance syndrome
Drug target
Acolbifene hydrochloride: D02758
Afimoxifene: D06551
Alfatradiol: D07121
Arzoxifene hydrochloride: D02993
Bazedoxifene: D03062
Brilanestrant: D11264
Chlorotrianisene: D00269
Clometherone: D03551
Clomifene (DG00474): D00962 D07726
Danazol: D00289
Delmadinone (DG02935): D03675 D07783
Desogestrel: D02367
Dienestrol: D00898
Diethylstilbestrol (DG00466): D00577 D00946 D07826
Droloxifene (DG01265): D03911 D03912
Elacestrant (DG03078): D11671 D11672
Enclomiphene (DG01992): D08910 D10876
Epitiostanol: D01265
Equilin: D04041
Estetrol (DG03027): D11513 D11514
Estradiol (DG00462): D00105 D01413 D01617 D01953 D04061 D04063 D04064 D04065 D07918 D07919
Estriol (DG00463): D00185 D01986 D01989 D07920 D07921
Estrogens, esterified: D04071
Estrone (DG00464): D00067 D00312 D00948
Ethinylestradiol (DG00461): D00554 D07928
Etonogestrel: D04104
Etynodiol (DG00470): D01294 D07939
Fispemifene: D10008
Fulvestrant: D01161
Hexestrol (DG02847): D01641 D02018
Idoxifene: D04496
Lasofoxifene: D04672
Levormeloxifene fumarate: D09834
Mepitiostane: D01602
Mestranol: D00575
Miproxifene phosphate: D01853
Nafoxidine hydrochloride: D05106
Nitromifene citrate: D05192
Ormeloxifen: D08301
Ospemifene: D08958
Polyestradiol phosphate: D07434
Prasterone (DG00141): D01616 D08409
Promestriene: D07221
Quinestrol: D00576
Raloxifene (DG00476): D02217 D08465 D10606
Tamoxifen (DG00734): D00966 D08559
Tibolone: D01639
Toremifene (DG00735): D00967 D08620
Trioxifene mesylate: D06245
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    2099 (ESR1)
   04917 Prolactin signaling pathway
    2099 (ESR1)
   04919 Thyroid hormone signaling pathway
    2099 (ESR1)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    2099 (ESR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2099 (ESR1)
   05205 Proteoglycans in cancer
    2099 (ESR1)
  09162 Cancer: specific types
   05224 Breast cancer
    2099 (ESR1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    2099 (ESR1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    2099 (ESR1)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:hsa03310]
    2099 (ESR1)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Zinc finger
   Cys4 estrogen-like
    2099 (ESR1)
Nuclear receptors [BR:hsa03310]
 3. Estrogen like
  3A. Estrogen receptor
   2099 (ESR1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Oest_recep Hormone_recep zf-C4 ESR1_C
Motif
Other DBs
NCBI-GeneID: 2099
NCBI-ProteinID: NP_000116
OMIM: 133430
HGNC: 3467
Ensembl: ENSG00000091831
Vega: OTTHUMG00000016103
Pharos: P03372(Tclin)
UniProt: P03372 G4XH65
LinkDB All DBs
Structure
PDB: 
5DXE 5UFX 5UFW 5KCT 3UUD 2IOG 1XPC 6CBZ 5W9D 6CHZ 2QXS 1XP6 2QZO 6SUO 5FQV 6SQ0 4ZNV 5KD9 2B1Z 5WGD 5W9C 4MGA 2B1V 1XP9 1XP1 5KCD 2YJA 6IAR 2POG 6OWC 5KCE 4TV1 4MG8 4MGB 2QSE 2QA8 5U2D 5TN4 5DXG 4ZNS 5FQP 5FQR 5ACC 6CHW 5TN5 2QAB 5TLT 5DZI 5AAU 4ZNT 4TUZ 4PXM 4MGD 3L03 2AYR 1YIM 1SJ0 3ERT 5KCW 5DWE 4ZN7 4ZNH 4PPS 4IWF 5FQS 2P15 5AAV 4IVY 2Q70 1L2I 5E1C 4IW6 5TM8 5FQT 6C42 5E0W 5DWJ 4MG9 2R6W 2R6Y 2QR9 2OUZ 2BJ4 1X7R 5E0X 5KCU 5DY8 3OS8 3ERD 4IW8 5TMT 4MG5 3UUA 3Q95 1XQC 5TN1 4IVW 5KCF 5DRJ 5TNB 5TLP 5DXB 5TN6 5DX3 5DUE 6DFN 5TLX 5T1Z 5KRO 5JMM 5E15 5DL4 4MG6 3UUC 2JF9 2FAI 2B23 5DZH 5TLY 4IV2 5DZ3 5DKG 4MG7 4MGC 2QGT 5TMO 5TM3 5KRF 5AK2 6PET 5TMM 5TLF 5DZ1 5DXP 5DU5 4PP6 3UU7 1YIN 5TMZ 5U2B 5TLU 5T92 5E14 4ZN9 5TM1 5TLG 5DXK 5TMQ 5TMS 5TN7 5TM5 5KRH 5KRM 5E19 5DZ0 5DUH 5DRM 5DIG 5DI7 5DID 5DIE 4Q13 4IWC 6PIT 5TML 5TN9 5TM4 5KR9 5KRI 5DUG 1ZKY 5DLR 5HYR 5DYB 5TLO 5DXR 5DVS 5DK9 1UOM 5TMW 4IU7 5WGQ 5TMR 5DWG 5DTV 4IV4 4IUI 4DMA 3OS9 3OSA 2QXM 2G5O 4ZNW 5TLV 3HM1 5DXM 5TMV 5TLD 5DP0 5KRK 5KCC 2QGW 5TM7 5GS4 5KRA 5KRC 5KRL 5EI1 5DXQ 5DMC 5DMF 5DKB 4ZNU 3DT3 2QE4 2IOK 1GWR 1HCQ 5TLL 5TMU 5DWI 1GWQ 5DYD 4XI3 6DF6 6D0F 6CZN 5TM9 5TLM 5EHJ 5DVV 5TN3 5TM6 2JFA 5TM2 5DKE 5DKS 4AA6 2YAT 2QA6 1ERR 5TN8 2G44 5EIT 4PPP 5KRJ 2QH6 2Q6J 1R5K 1PCG 5GTR 1X7E 1A52 6PFM 6B0F 5EGV 2I0J 1G50 2OCF 5T97 3HLV 4Q50 1ERE 1QKU 1QKT 1HCP
Thumbnails

Position
6q25.1-q25.2
AA seq 595 aa AA seqDB search
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
NT seq 1788 nt NT seq  +upstreamnt  +downstreamnt
atgaccatgaccctccacaccaaagcatctgggatggccctactgcatcagatccaaggg
aacgagctggagcccctgaaccgtccgcagctcaagatccccctggagcggcccctgggc
gaggtgtacctggacagcagcaagcccgccgtgtacaactaccccgagggcgccgcctac
gagttcaacgccgcggccgccgccaacgcgcaggtctacggtcagaccggcctcccctac
ggccccgggtctgaggctgcggcgttcggctccaacggcctggggggtttccccccactc
aacagcgtgtctccgagcccgctgatgctactgcacccgccgccgcagctgtcgcctttc
ctgcagccccacggccagcaggtgccctactacctggagaacgagcccagcggctacacg
gtgcgcgaggccggcccgccggcattctacaggccaaattcagataatcgacgccagggt
ggcagagaaagattggccagtaccaatgacaagggaagtatggctatggaatctgccaag
gagactcgctactgtgcagtgtgcaatgactatgcttcaggctaccattatggagtctgg
tcctgtgagggctgcaaggccttcttcaagagaagtattcaaggacataacgactatatg
tgtccagccaccaaccagtgcaccattgataaaaacaggaggaagagctgccaggcctgc
cggctccgtaaatgctacgaagtgggaatgatgaaaggtgggatacgaaaagaccgaaga
ggagggagaatgttgaaacacaagcgccagagagatgatggggagggcaggggtgaagtg
gggtctgctggagacatgagagctgccaacctttggccaagcccgctcatgatcaaacgc
tctaagaagaacagcctggccttgtccctgacggccgaccagatggtcagtgccttgttg
gatgctgagcccccgatactctattccgagtatgatcctaccagacccttcagtgaagct
tcgatgatgggcttactgaccaacctggcagacagggagctggttcacatgatcaactgg
gcgaagagggtgccaggctttgtggatttgaccctccatgatcaggtccaccttctagaa
tgtgcctggctagagatcctgatgattggtctcgtctggcgctccatggagcacccaggg
aagctactgtttgctcctaacttgctcttggacaggaaccagggaaaatgtgtagagggc
atggtggagatcttcgacatgctgctggctacatcatctcggttccgcatgatgaatctg
cagggagaggagtttgtgtgcctcaaatctattattttgcttaattctggagtgtacaca
tttctgtccagcaccctgaagtctctggaagagaaggaccatatccaccgagtcctggac
aagatcacagacactttgatccacctgatggccaaggcaggcctgaccctgcagcagcag
caccagcggctggcccagctcctcctcatcctctcccacatcaggcacatgagtaacaaa
ggcatggagcatctgtacagcatgaagtgcaagaacgtggtgcccctctatgacctgctg
ctggagatgctggacgcccaccgcctacatgcgcccactagccgtggaggggcatccgtg
gaggagacggaccaaagccacttggccactgcgggctctacttcatcgcattccttgcaa
aagtattacatcacgggggaggcagagggtttccctgccacggtctga

KEGG   Homo sapiens (human): 2100Help
Entry
2100              CDS       T01001                                 

Gene name
ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2, ODG8
Definition
(RefSeq) estrogen receptor 2
  KO
K08551  estrogen receptor beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa01522  Endocrine resistance
hsa04915  Estrogen signaling pathway
hsa04917  Prolactin signaling pathway
hsa04929  GnRH secretion
hsa05200  Pathways in cancer
hsa05224  Breast cancer
Network
nt06227  NR signaling
nt06270  Breast cancer
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00286  Nuclear-initiated estrogen signaling pathway
Drug target
Acolbifene hydrochloride: D02758
Afimoxifene: D06551
Alfatradiol: D07121
Arzoxifene hydrochloride: D02993
Bazedoxifene: D03062
Brilanestrant: D11264
Chlorotrianisene: D00269
Clometherone: D03551
Clomifene (DG00474): D00962 D07726
Delmadinone (DG02935): D03675 D07783
Dienestrol: D00898
Diethylstilbestrol (DG00466): D00577 D00946 D07826
Droloxifene (DG01265): D03911 D03912
Enclomiphene (DG01992): D08910 D10876
Epitiostanol: D01265
Equilin: D04041
Erteberel: D09899
Estetrol (DG03027): D11513 D11514
Estradiol (DG00462): D00105 D01413 D01617 D01953 D04061 D04063 D04064 D04065 D07918 D07919
Estriol (DG00463): D00185 D01986 D01989 D07920 D07921
Estrogens, esterified: D04071
Estrone (DG00464): D00067 D00312 D00948
Fispemifene: D10008
Fulvestrant: D01161
Hexestrol (DG02847): D01641 D02018
Idoxifene: D04496
Lasofoxifene: D04672
Levormeloxifene fumarate: D09834
Mepitiostane: D01602
Mestranol: D00575
Miproxifene phosphate: D01853
Nafoxidine hydrochloride: D05106
Nitromifene citrate: D05192
Ormeloxifen: D08301
Prasterone (DG00141): D01616 D08409
Prinaberel: D06631
Promestriene: D07221
Raloxifene (DG00476): D02217 D08465 D10606
Tamoxifen (DG00734): D00966 D08559
Toremifene (DG00735): D00967 D08620
Trioxifene mesylate: D06245
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    2100 (ESR2)
   04915 Estrogen signaling pathway
    2100 (ESR2)
   04917 Prolactin signaling pathway
    2100 (ESR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2100 (ESR2)
  09162 Cancer: specific types
   05224 Breast cancer
    2100 (ESR2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    2100 (ESR2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    2100 (ESR2)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:hsa03310]
    2100 (ESR2)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Zinc finger
   Cys4 estrogen-like
    2100 (ESR2)
Nuclear receptors [BR:hsa03310]
 3. Estrogen like
  3A. Estrogen receptor
   2100 (ESR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: ERbeta_N Hormone_recep zf-C4
Motif
Other DBs
NCBI-GeneID: 2100
NCBI-ProteinID: NP_001428
OMIM: 601663
HGNC: 3468
Ensembl: ENSG00000140009
Vega: OTTHUMG00000141306
Pharos: Q92731(Tclin)
UniProt: Q92731 Q7LCB3
LinkDB All DBs
Structure
PDB: 

Position
14q23.2-q23.3
AA seq 530 aa AA seqDB search
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK
CKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
NT seq 1593 nt NT seq  +upstreamnt  +downstreamnt
atggatataaaaaactcaccatctagccttaattctccttcctcctacaactgcagtcaa
tccatcttacccctggagcacggctccatatacataccttcctcctatgtagacagccac
catgaatatccagccatgacattctatagccctgctgtgatgaattacagcattcccagc
aatgtcactaacttggaaggtgggcctggtcggcagaccacaagcccaaatgtgttgtgg
ccaacacctgggcacctttctcctttagtggtccatcgccagttatcacatctgtatgcg
gaacctcaaaagagtccctggtgtgaagcaagatcgctagaacacaccttacctgtaaac
agagagacactgaaaaggaaggttagtgggaaccgttgcgccagccctgttactggtcca
ggttcaaagagggatgctcacttctgcgctgtctgcagcgattacgcatcgggatatcac
tatggagtctggtcgtgtgaaggatgtaaggccttttttaaaagaagcattcaaggacat
aatgattatatttgtccagctacaaatcagtgtacaatcgataaaaaccggcgcaagagc
tgccaggcctgccgacttcggaagtgttacgaagtgggaatggtgaagtgtggctcccgg
agagagagatgtgggtaccgccttgtgcggagacagagaagtgccgacgagcagctgcac
tgtgccggcaaggccaagagaagtggcggccacgcgccccgagtgcgggagctgctgctg
gacgccctgagccccgagcagctagtgctcaccctcctggaggctgagccgccccatgtg
ctgatcagccgccccagtgcgcccttcaccgaggcctccatgatgatgtccctgaccaag
ttggccgacaaggagttggtacacatgatcagctgggccaagaagattcccggctttgtg
gagctcagcctgttcgaccaagtgcggctcttggagagctgttggatggaggtgttaatg
atggggctgatgtggcgctcaattgaccaccccggcaagctcatctttgctccagatctt
gttctggacagggatgaggggaaatgcgtagaaggaattctggaaatctttgacatgctc
ctggcaactacttcaaggtttcgagagttaaaactccaacacaaagaatatctctgtgtc
aaggccatgatcctgctcaattccagtatgtaccctctggtcacagcgacccaggatgct
gacagcagccggaagctggctcacttgctgaacgccgtgaccgatgctttggtttgggtg
attgccaagagcggcatctcctcccagcagcaatccatgcgcctggctaacctcctgatg
ctcctgtcccacgtcaggcatgcgagtaacaagggcatggaacatctgctcaacatgaag
tgcaaaaatgtggtcccagtgtatgacctgctgctggagatgctgaatgcccacgtgctt
cgcgggtgcaagtcctccatcacggggtccgagtgcagcccggcagaggacagtaaaagc
aaagagggctcccagaacccacagtctcagtga

KEGG   Homo sapiens (human): 8648Help
Entry
8648              CDS       T01001                                 

Gene name
NCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74
Definition
(RefSeq) nuclear receptor coactivator 1
  KO
K09101  nuclear receptor coactivator 1 [EC:2.3.1.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04915  Estrogen signaling pathway
hsa04919  Thyroid hormone signaling pathway
hsa05200  Pathways in cancer
hsa05224  Breast cancer
Network
nt06227  NR signaling
nt06270  Breast cancer
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00286  Nuclear-initiated estrogen signaling pathway
N00287  ESR1-positive to nuclear-initiated estrogen signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    8648 (NCOA1)
   04919 Thyroid hormone signaling pathway
    8648 (NCOA1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    8648 (NCOA1)
  09162 Cancer: specific types
   05224 Breast cancer
    8648 (NCOA1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    8648 (NCOA1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     8648 (NCOA1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    8648 (NCOA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PAS_11 NCOA_u2 DUF1518 SRC-1 Nuc_rec_co-act PAS PAS_3 DUF4927 PAS_9 HLH PAS_12 PAS_4
Motif
Other DBs
NCBI-GeneID: 8648
NCBI-ProteinID: NP_003734
OMIM: 602691
HGNC: 7668
Ensembl: ENSG00000084676
Vega: OTTHUMG00000125523
Pharos: Q15788(Tchem)
UniProt: Q15788
LinkDB All DBs
Structure
PDB: 

Position
2p23.3
AA seq 1441 aa AA seqDB search
MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSL
SVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEAL
DGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNG
VPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQ
SCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFF
QPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMG
IHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINR
QQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGTG
ISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS
LQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDN
SSSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSC
TGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDSASTSVS
VTGQVQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVKVEKKEQ
MDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQFDQLLPTLEKAAQLPGLCETDRMDGAV
TSVTIKSEILPASLQSATARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAIN
QSKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKL
VQGGGLDVLSERFPPQQATPPLIMEERPNLYSQPYSSPSPTANLPSPFQGMVRQKPSLGT
MPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILNQF
AATAPVGINMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAMLMRQQSF
GNNLPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLAN
RNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPI
PPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVS
MAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSSTDLLKTE
ADGTQQVQQVQVFADVQCTVNLVGGDPYLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLT
E
NT seq 4326 nt NT seq  +upstreamnt  +downstreamnt
atgagtggcctcggggacagttcatccgaccctgctaacccagactcacataagaggaaa
ggatcgccatgtgacacactggcatcaagcacggaaaagaggcgcagggagcaagaaaat
aaatatttagaagaactagctgagttactgtctgccaacattagtgacattgacagcttg
agtgtaaaaccagacaaatgcaagattttgaagaaaacagtcgatcagatacagctaatg
aagagaatggaacaagagaaatcaacaactgatgacgatgtacagaaatcagacatctca
tcaagtagtcaaggagtgatagaaaaggaatccttgggacctcttcttttggaggctttg
gatggatttttctttgttgtgaactgtgaagggagaattgtatttgtgtcagagaatgta
accagctacttaggttacaatcaggaggaattaatgaatacgagcgtctacagcatactg
cacgtgggggatcatgcagaatttgtgaagaatctgctaccaaaatcactagtaaatgga
gttccttggcctcaagaggcaacacgacgaaatagccatacctttaactgcaggatgcta
attcaccctccagatgagccagggaccgagaaccaagaagcttgccagcgttatgaagta
atgcagtgtttcactgtgtcacagccaaaatcaattcaagaggatggagaagatttccag
tcatgtctgatttgtattgcacggcgattacctcggcctccagctattacgggtgtagaa
tcctttatgaccaagcaagatactacaggtaaaatcatctctattgatactagttccctg
agagctgctggcagaactggttgggaagatttagtgaggaagtgcatttatgcttttttc
caacctcagggcagagaaccatcttatgccagacagctgttccaagaagtgatgactcgt
ggcactgcctccagcccctcctatagattcatattgaatgatgggacaatgcttagcgcc
cacaccaagtgtaaactttgctaccctcaaagtccagacatgcaacctttcatcatggga
attcatatcatcgacagggagcacagtgggctttctcctcaagatgacactaattctgga
atgtcaattccccgagtaaatccctcggtcaatcctagtatctctccagctcatggtgtg
gctcgttcatccacattgccaccatccaacagcaacatggtatccaccagaataaaccgc
cagcagagctcagaccttcatagcagcagtcatagtaattctagcaacagccaaggaagt
ttcggatgctcacccggaagtcagattgtagccaatgttgccttaaaccaaggacaggcc
agttcacagagcagtaatccctctttaaacctcaataattctcctatggaaggtacagga
atatccctagcacagttcatgtctccaaggagacaggttacttctggattggcaacaagg
cccaggatgccaaacaattcctttcctcctaatatttcgacattaagctctcccgttggc
atgacaagtagtgcctgtaataataataaccgatcttattcaaacatcccagtaacatct
ttacagggtatgaatgaaggacccaataactccgttggcttctctgccagttctccagtc
ctcaggcagatgagctcacagaattcacctagcagattaaatatacaaccagcaaaagct
gagtccaaagataacaaagagattgcctcaattttaaatgaaatgattcaatctgacaac
agctctagtgatggcaaacctctggattcagggcttctgcataacaatgacagactttca
gatggagacagtaaatactctcaaaccagtcacaaactagtgcagcttttgacaacaact
gccgaacagcagttacggcatgctgatatagacacaagctgcaaagatgtcctgtcttgc
acaggcacttccaactctgcctctgctaactcttcaggaggttcttgtccctcttctcat
agctcattgacagaacggcataaaattctacaccggctcttacaggagggtagcccctca
gatatcaccactttgtctgtcgagcctgataaaaaggacagtgcatctacttctgtgtca
gtgactggacaggtacaaggaaactccagtataaaactagaactggatgcttcaaagaaa
aaagaatcaaaagaccatcagctcctacgctatcttttagataaagatgagaaagattta
agatcaactccaaacctgagcctggatgatgtaaaggtgaaagtggaaaagaaagaacag
atggatccatgtaatacaaacccaaccccaatgaccaaacccactcctgaggaaataaaa
ctggaggcccagagccagtttacagctgaccttgaccagtttgatcagttactgcccacg
ctggagaaggcagcacagttgccaggcttatgtgagacagacaggatggatggtgcggtc
accagtgtaaccatcaaatcggagatcctgccagcttcacttcagtccgccactgccaga
cccacttccaggctaaatagattacctgagctggaattggaagcaattgataaccaattt
ggacaaccaggaacaggcgatcagattccatggacaaataatacagtgacagctataaat
cagagtaaatcagaagaccagtgtattagctcacaattagatgagcttctctgtccaccc
acaacagtagaagggagaaatgatgagaaggctcttcttgaacagctggtatccttcctt
agtggcaaagatgaaactgagctagctgaactagacagagctctgggaattgacaaactt
gttcaggggggtggattagatgtattatcagagagatttccaccacaacaagcaacgcca
cctttgatcatggaagaaagacccaacctttattcccagccttactcttctccttctcct
actgccaatctccctagccctttccaaggcatggtcaggcaaaaaccttcactggggacg
atgcctgttcaagtaacacctccccgaggtgctttttcacctggcatgggcatgcagccc
aggcaaactctaaacagacctccggctgcacctaaccagcttcgacttcaactacagcag
cgattacagggacaacagcagttgatacaccaaaatcggcaagctatcttaaaccagttt
gcagcaactgctcctgttggcatcaatatgagatcaggcatgcaacagcaaattacacct
cagccacccctgaatgctcaaatgttggcacaacgtcagcgggaactgtacagtcaacag
caccgacagaggcagctaatacagcagcaaagagccatgcttatgaggcagcaaagcttt
gggaacaacctccctccctcatctggactaccagttcaaatggggaacccccgtcttcct
cagggtgctccacagcaattcccctatccaccaaactatggtacaaatccaggaacccca
cctgcttctaccagcccgttttcacaactagcagcaaatcctgaagcatccttggccaac
cgcaacagcatggtgagcagaggcatgacaggaaacataggaggacagtttggcactgga
atcaatcctcagatgcagcagaatgtcttccagtatccaggagcaggaatggttccccaa
ggtgaggccaactttgctccatctctaagccctgggagctccatggtgccgatgccaatc
cctcctcctcagagttctcttctccagcaaactccacctgcctccgggtatcagtcacca
gacatgaaggcctggcagcaaggagcgataggaaacaacaatgtgttcagtcaagctgtc
cagaaccagcccacgcctgcacagccaggagtatacaacaacatgagcatcaccgtttcc
atggcaggtggaaatacgaatgttcagaacatgaacccaatgatggcccagatgcagatg
agctctttgcagatgccaggaatgaacactgtgtgccctgagcagataaatgatcccgca
ctgagacacacaggcctctactgcaaccagctctcatccactgaccttctcaaaacagaa
gcagatggaacccagcaggtgcaacaggttcaggtgtttgctgacgtccagtgtacagtg
aatctggtaggcggggacccttacctgaaccagcctggtccactgggaactcaaaagccc
acgtcaggaccacagaccccccaggcccagcagaagagcctccttcagcagctactgact
gaataa

KEGG   Homo sapiens (human): 10499Help
Entry
10499             CDS       T01001                                 

Gene name
NCOA2, GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75
Definition
(RefSeq) nuclear receptor coactivator 2
  KO
K11255  nuclear receptor coactivator 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04915  Estrogen signaling pathway
hsa04919  Thyroid hormone signaling pathway
Network
nt06227  NR signaling
nt06270  Breast cancer
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00286  Nuclear-initiated estrogen signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    10499 (NCOA2)
   04919 Thyroid hormone signaling pathway
    10499 (NCOA2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    10499 (NCOA2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    10499 (NCOA2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: NCOA_u2 PAS_11 DUF4927 DUF1518 Nuc_rec_co-act SRC-1 PAS PAS_3 PAS_9 HLH
Motif
Other DBs
NCBI-GeneID: 10499
NCBI-ProteinID: NP_001308632
OMIM: 601993
HGNC: 7669
Ensembl: ENSG00000140396
Vega: OTTHUMG00000164671
Pharos: Q15596(Tbio)
UniProt: Q15596
LinkDB All DBs
Position
8q13.3
AA seq 1464 aa AA seqDB search
MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT
PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN
TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG
NLFPNQLPGMDMIKQEGDTTRKYC
NT seq 4395 nt NT seq  +upstreamnt  +downstreamnt
atgagtgggatgggagaaaatacctctgacccctccagggcagagacaagaaagcgcaag
gaatgtcctgaccaacttggacccagccccaaaaggaacactgaaaaacgtaatcgtgaa
caggaaaataaatatatagaagaacttgcagagttgatttttgcaaattttaatgatata
gacaactttaacttcaaacctgacaaatgtgcaatcttaaaagaaactgtgaagcaaatt
cgtcagatcaaagaacaagagaaagcagcagctgccaacatagatgaagtgcagaagtca
gatgtatcctctacagggcagggtgtcatcgacaaggatgcgctggggcctatgatgctt
gaggcccttgatgggttcttctttgtagtgaacctggaaggcaacgttgtgtttgtgtca
gagaatgtgacacagtatctaaggtataaccaagaagagctgatgaacaaaagtgtatat
agcatcttgcatgttggggaccacacggaatttgtcaaaaacctgctgccaaagtctata
gtaaatgggggatcttggtctggcgaacctccgaggcggaacagccataccttcaattgt
cggatgctggtaaaacctttacctgattcagaagaggagggtcatgataaccaggaagct
catcagaaatatgaaactatgcagtgcttcgctgtctctcaaccaaagtccatcaaagaa
gaaggagaagatttgcagtcctgcttgatttgcgtggcaagaagagttcccatgaaggaa
agaccagttcttccctcatcagaaagttttactactcgccaggatctccaaggcaagatc
acgtctctggataccagcaccatgagagcagccatgaaaccaggctgggaggacctggta
agaaggtgtattcagaagttccatgcgcagcatgaaggagaatctgtgtcctatgctaag
aggcatcatcatgaagtactgagacaaggattggcattcagtcaaatctatcgtttttcc
ttgtctgatggcactcttgttgctgcacaaacgaagagcaaactcatccgttctcagact
actaatgaacctcaacttgtaatatctttacatatgcttcacagagagcagaatgtgtgt
gtgatgaatccggatctgactggacaaacgatggggaagccactgaatccaattagctct
aacagccctgcccatcaggccctgtgcagtgggaacccaggtcaggacatgaccctcagt
agcaatataaattttcccataaatggcccaaaggaacaaatgggcatgcccatgggcagg
tttggtggttctgggggaatgaaccatgtgtcaggcatgcaagcaaccactcctcagggt
agtaactatgcactcaaaatgaacagcccctcacaaagcagccctggcatgaatccagga
cagcccacctccatgctttcaccaaggcatcgcatgagccctggagtggctggcagccct
cgaatcccacccagtcagttttcccctgcaggaagcttgcattcccctgtgggagtttgc
agcagcacaggaaatagccatagttataccaacagctccctcaatgcacttcaggccctc
agcgaggggcacggggtctcattagggtcatcgttggcttcaccagacctaaaaatgggc
aatttgcaaaactccccagttaatatgaatcctcccccactcagcaagatgggaagcttg
gactcaaaagactgttttggactatatggggagccctctgaaggtacaactggacaagca
gagagcagctgccatcctggagagcaaaaggaaacaaatgaccccaacctgcccccggcc
gtgagcagtgagagagctgacgggcagagcagactgcatgacagcaaagggcagaccaaa
ctcctgcagctgctgaccaccaaatctgatcagatggagccctcgcccttagccagctct
ttgtcggatacaaacaaagactccacaggtagcttgcctggttctgggtctacacatgga
acctcgctcaaggagaagcataaaattttgcacagactcttgcaggacagcagttcccct
gtggacttggccaagttaacagcagaagccacaggcaaagacctgagccaggagtccagc
agcacagctcctggatcagaagtgactattaaacaagagccggtgagccccaagaagaaa
gagaatgcactacttcgctatttgctagataaagatgatactaaagatattggtttacca
gaaataacccccaaacttgagagactggacagtaagacagatcctgccagtaacacaaaa
ttaatagcaatgaaaactgagaaggaggagatgagctttgagcctggtgaccagcctggc
agtgagctggacaacttggaggagattttggatgatttgcagaatagtcaattaccacag
cttttcccagacacgaggccaggcgcccctgctggatcagttgacaagcaagccatcatc
aatgacctcatgcaactcacagctgaaaacagccctgtcacacctgttggagcccagaaa
acagcactgcgaatttcacagagcacttttaataacccacgaccagggcaactgggcagg
ttattgccaaaccagaatttaccacttgacatcacattgcaaagcccaactggtgctgga
cctttcccaccaatcagaaacagtagtccctactcagtgatacctcagccaggaatgatg
ggtaatcaagggatgataggaaaccaaggaaatttagggaacagtagcacaggaatgatt
ggtaacagtgcttctcggcctactatgccatctggagaatgggcaccgcagagttcggct
gtgagagtcacctgtgctgctaccaccagtgccatgaaccggccagtccaaggaggtatg
attcggaacccagcagccagcatccccatgaggcccagcagccagcctggccaaagacag
acgcttcagtctcaggtcatgaatatagggccatctgaattagagatgaacatgggggga
cctcagtatagccaacaacaagctcctccaaatcagactgccccatggcctgaaagcatc
ctgcctatagaccaggcgtcttttgccagccaaaacaggcagccatttggcagttctcca
gatgacttgctatgtccacatcctgcagctgagtctccgagtgatgagggagctctcctg
gaccagctgtatctggccttgcggaattttgatggcctggaggagattgatagagcctta
ggaatacccgaactggtcagccagagccaagcagtagatccagaacagttctcaagtcag
gattccaacatcatgctggagcagaaggcgcccgttttcccacagcagtatgcatctcag
gcacaaatggcccagggtagctattctcccatgcaagatccaaactttcacaccatggga
cagcggcctagttatgccacactccgtatgcagcccagaccgggcctcaggcccacgggc
ctagtgcagaaccagccaaatcaactaagacttcaacttcagcatcgcctccaagcacag
cagaatcgccagccacttatgaatcaaatcagcaatgtttccaatgtgaacttgactctg
aggcctggagtaccaacacaggcacctattaatgcacagatgctggcccagagacagagg
gaaatcctgaaccagcatcttcgacagagacaaatgcatcagcaacagcaagttcagcaa
cgaactttgatgatgagaggacaagggttgaatatgacaccaagcatggtggctcctagt
ggtatgccagcaactatgagcaaccctcggattccccaggcaaatgcacagcagtttcca
tttcctccaaactacggaataagtcagcaacctgatccaggctttactggggctacgact
ccccagagcccacttatgtcaccccgaatggcacatacacagagtcccatgatgcaacag
tctcaggccaacccagcctatcaggccccctccgacataaatggatgggcgcaggggaac
atgggcggaaacagcatgttttcccagcagtccccaccacactttgggcagcaagcaaac
accagcatgtacagtaacaacatgaacatcaatgtgtccatggcgaccaacacaggtggc
atgagcagcatgaaccagatgacaggacagatcagcatgacctcagtgacctccgtgcct
acgtcagggctgtcctccatgggtcccgagcaggttaatgatcctgctctgaggggaggc
aacctgttcccaaaccagctgcctggaatggatatgattaagcaggagggagacacaaca
cggaaatattgctga

KEGG   Homo sapiens (human): 8202Help
Entry
8202              CDS       T01001                                 

Gene name
NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP
Definition
(RefSeq) nuclear receptor coactivator 3
  KO
K11256  nuclear receptor coactivator 3 [EC:2.3.1.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa01522  Endocrine resistance
hsa04915  Estrogen signaling pathway
hsa04919  Thyroid hormone signaling pathway
hsa05200  Pathways in cancer
hsa05224  Breast cancer
Network
nt06227  NR signaling
nt06270  Breast cancer
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00286  Nuclear-initiated estrogen signaling pathway
N00287  ESR1-positive to nuclear-initiated estrogen signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    8202 (NCOA3)
   04919 Thyroid hormone signaling pathway
    8202 (NCOA3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    8202 (NCOA3)
  09162 Cancer: specific types
   05224 Breast cancer
    8202 (NCOA3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    8202 (NCOA3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    8202 (NCOA3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     8202 (NCOA3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    8202 (NCOA3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: NCOA_u2 PAS_11 DUF4927 SRC-1 Nuc_rec_co-act DUF1518 PAS PAS_3 PAS_9 HLH AIM3 PAS_4 TERB2
Motif
Other DBs
NCBI-GeneID: 8202
NCBI-ProteinID: NP_858045
OMIM: 601937
HGNC: 7670
Ensembl: ENSG00000124151
Vega: OTTHUMG00000033061
Pharos: Q9Y6Q9(Tbio)
UniProt: Q9Y6Q9
LinkDB All DBs
Structure
PDB: 

Position
20q13.12
AA seq 1424 aa AA seqDB search
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDID
NFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQA
LDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGE
DLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRC
IQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR
HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLA
DPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNI
MISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST
LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKE
SSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVS
SSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN
VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQE
KDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLK
SSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS
SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPT
LPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQV
SHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE
LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMN
QMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTA
GGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ
QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQ
PDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQ
FAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC
NT seq 4275 nt NT seq  +upstreamnt  +downstreamnt
atgagtggattaggagaaaacttggatccactggccagtgattcacgaaaacgcaaattg
ccatgtgatactccaggacaaggtcttacctgcagtggtgaaaaacggagacgggagcag
gaaagtaaatatattgaagaattggctgagctgatatctgccaatcttagtgatattgac
aatttcaatgtcaaaccagataaatgtgcgattttaaaggaaacagtaagacagatacgt
caaataaaagagcaaggaaaaactatttccaatgatgatgatgttcaaaaagccgatgta
tcttctacagggcagggagttattgataaagactccttaggaccgcttttacttcaggca
ttggatggtttcctatttgtggtgaatcgagacggaaacattgtatttgtatcagaaaat
gtcacacaatacctgcaatataagcaagaggacctggttaacacaagtgtttacaatatc
ttacatgaagaagacagaaaggattttcttaagaatttaccaaaatctacagttaatgga
gtttcctggacaaatgagacccaaagacaaaaaagccatacatttaattgccgtatgttg
atgaaaacaccacatgatattctggaagacataaacgccagtcctgaaatgcgccagaga
tatgaaacaatgcagtgctttgccctgtctcagccacgagctatgatggaggaaggggaa
gatttgcaatcttgtatgatctgtgtggcacgccgcattactacaggagaaagaacattt
ccatcaaaccctgagagctttattaccagacatgatctttcaggaaaggttgtcaatata
gatacaaattcactgagatcctccatgaggcctggctttgaagatataatccgaaggtgt
attcagagattttttagtctaaatgatgggcagtcatggtcccagaaacgtcactatcaa
gaagcttatcttaatggccatgcagaaaccccagtatatcgattctcgttggctgatgga
actatagtgactgcacagacaaaaagcaaactcttccgaaatcctgtaacaaatgatcga
catggctttgtctcaacccacttccttcagagagaacagaatggatatagaccaaaccca
aatcctgttggacaagggattagaccacctatggctggatgcaacagttcggtaggcggc
atgagtatgtcgccaaaccaaggcttacagatgccgagcagcagggcctatggcttggca
gaccctagcaccacagggcagatgagtggagctaggtatgggggttccagtaacatagct
tcattgacccctgggccaggcatgcaatcaccatcttcctaccagaacaacaactatggg
ctcaacatgagtagccccccacatgggagtcctggtcttgccccaaaccagcagaatatc
atgatttctcctcgtaatcgtgggagtccaaagatagcctcacatcagttttctcctgtt
gcaggtgtgcactctcccatggcatcttctggcaatactgggaaccacagcttttccagc
agctctctcagtgccctgcaagccatcagtgaaggtgtggggacttcccttttatctact
ctgtcatcaccaggccccaaattggataactctcccaatatgaatattacccaaccaagt
aaagtaagcaatcaggattccaagagtcctctgggcttttattgcgaccaaaatccagtg
gagagttcaatgtgtcagtcaaatagcagagatcacctcagtgacaaagaaagtaaggag
agcagtgttgagggggcagagaatcaaaggggtcctttggaaagcaaaggtcataaaaaa
ttactgcagttacttacctgttcttctgatgaccggggtcattcctccttgaccaactcc
cccctagattcaagttgtaaagaatcttctgttagtgtcaccagcccctctggagtctcc
tcctctacatctggaggagtatcctctacatccaatatgcatgggtcactgttacaagag
aagcaccggattttgcacaagttgctgcagaatgggaattcaccagctgaggtagccaag
attactgcagaagccactgggaaagacaccagcagtataacttcttgtggggacggaaat
gttgtcaagcaggagcagctaagtcctaagaagaaggagaataatgcacttcttagatac
ctgctggacagggatgatcctagtgatgcactctctaaagaactacagccccaagtggaa
ggagtggataataaaatgagtcagtgcaccagctccaccattcctagctcaagtcaagag
aaagaccctaaaattaagacagagacaagtgaagagggatctggagacttggataatcta
gatgctattcttggtgatctgactagttctgacttttacaataattccatatcctcaaat
ggtagtcatctggggactaagcaacaggtgtttcaaggaactaattctctgggtttgaaa
agttcacagtctgtgcagtctattcgtcctccatataaccgagcagtgtctctggatagc
cctgtttctgttggctcaagtcctccagtaaaaaatatcagtgctttccccatgttacca
aagcaacccatgttgggtgggaatccaagaatgatggatagtcaggaaaattatggctca
agtatgggtgggccaaaccgaaatgtgactgtgactcagactccttcctcaggagactgg
ggcttaccaaactcaaaggccggcagaatggaacctatgaattcaaactccatgggaaga
ccaggaggagattataatacttctttacccagacctgcactgggtggctctattcccaca
ttgcctcttcggtctaatagcataccaggtgcgagaccagtattgcaacagcagcagcag
atgcttcaaatgaggcctggtgaaatccccatgggaatgggggctaatccctatggccaa
gcagcagcatctaaccaactgggttcctggcccgatggcatgttgtccatggaacaagtt
tctcatggcactcaaaataggcctcttcttaggaattccctggatgatcttgttgggcca
ccttccaacctggaaggccagagtgacgaaagagcattattggaccagctgcacactctt
ctcagcaacacagatgccacaggcctggaagaaattgacagagctttgggcattcctgaa
cttgtcaatcagggacaggcattagagcccaaacaggatgctttccaaggccaagaagca
gcagtaatgatggatcagaaggcaggattatatggacagacatacccagcacaggggcct
ccaatgcaaggaggctttcatcttcagggacaatcaccatcttttaactctatgatgaat
cagatgaaccagcaaggcaattttcctctccaaggaatgcacccacgagccaacatcatg
agaccccggacaaacacccccaagcaacttagaatgcagcttcagcagaggctgcagggc
cagcagtttttgaatcagagccgacaggcacttgaattgaaaatggaaaaccctactgct
ggtggtgctgcggtgatgaggcctatgatgcagccccaggtgagctcccagcagggtttt
cttaatgctcaaatggtcgcccaacgcagcagagagctgctaagtcatcacttccgacaa
cagagggtggctatgatgatgcagcagcagcagcagcagcaacagcagcagcagcagcag
cagcagcagcaacagcaacagcaacagcaacagcagcaacagcagcaaacccaggccttc
agcccacctcctaatgtgactgcttcccccagcatggatgggcttttggcaggacccaca
atgccacaagctcctccgcaacagtttccatatcaaccaaattatggaatgggacaacaa
ccagatccagcctttggtcgagtgtctagtcctcccaatgcaatgatgtcgtcaagaatg
ggtccctcccagaatcccatgatgcaacacccgcaggctgcatccatctatcagtcctca
gaaatgaagggctggccatcaggaaatttggccaggaacagctccttttcccagcagcag
tttgcccaccaggggaatcctgcagtgtatagtatggtgcacatgaatggcagcagtggt
cacatgggacagatgaacatgaaccccatgcccatgtctggcatgcctatgggtcctgat
cagaaatactgctga

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