Homo sapiens (human): 2158
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Entry
2158 CDS
T01001
Symbol
F9, F9_p22, FIX, HEMB, P19, PTC, THPH8
Name
(RefSeq) coagulation factor IX
KO
K01321
coagulation factor IX (Christmas factor) [EC:
3.4.21.22
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04610
Complement and coagulation cascades
Network
nt06514
Coagulation cascade
Element
N01508
Intrinsic pathway of coagulation cascade, F9 activation
Disease
H00219
Hemophilia
H00223
Inherited thrombophilia
Drug target
Coagulation factor IX (
DG00171
):
D05201
<JP>
D08794
<JP>
D08797
<JP/US>
D10401
D10522
<JP>
D10538
D10757
<JP>
D10770
<JP>
Denecimig:
D12797
Emicizumab:
D10821
<JP/US>
Etranacogene dezaparvovec:
D12500
<US>
Fidanacogene elaparvovec:
D12908
<US>
Gruticibart:
D12541
Pegnivacogin (
DG01399
):
D10150
D10484
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
2158 (F9)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
2158 (F9)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.22 coagulation factor IXa
2158 (F9)
Peptidases and inhibitors [BR:
hsa01002
]
Serine peptidases
Family S1: chymotrypsin family
2158 (F9)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Trypsin
Gla
FXa_inhibition
EGF
cEGF
DUF1986
Trypsin_2
hEGF
EGF_3
Motif
Other DBs
NCBI-GeneID:
2158
NCBI-ProteinID:
NP_000124
OMIM:
300746
HGNC:
3551
Ensembl:
ENSG00000101981
CPD:
C03259
UniProt:
P00740
Structure
PDB
PDBj
LinkDB
All DBs
Position
X:139530739..139563459
Genome browser
AA seq
461 aa
AA seq
DB search
MQRVNMIMAESPGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGNL
ERECMEEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCP
FGFEGKNCELDVTCNIKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGR
VSVSQTSKLTRAETVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPW
QVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRII
PHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVF
HKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVE
GTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgcagcgcgtgaacatgatcatggcagaatcaccaggcctcatcaccatctgcctttta
ggatatctactcagtgctgaatgtacagtttttcttgatcatgaaaacgccaacaaaatt
ctgaatcggccaaagaggtataattcaggtaaattggaagagtttgttcaagggaacctt
gagagagaatgtatggaagaaaagtgtagttttgaagaagcacgagaagtttttgaaaac
actgaaagaacaactgaattttggaagcagtatgttgatggagatcagtgtgagtccaat
ccatgtttaaatggcggcagttgcaaggatgacattaattcctatgaatgttggtgtccc
tttggatttgaaggaaagaactgtgaattagatgtaacatgtaacattaagaatggcaga
tgcgagcagttttgtaaaaatagtgctgataacaaggtggtttgctcctgtactgaggga
tatcgacttgcagaaaaccagaagtcctgtgaaccagcagtgccatttccatgtggaaga
gtttctgtttcacaaacttctaagctcacccgtgctgagactgtttttcctgatgtggac
tatgtaaattctactgaagctgaaaccattttggataacatcactcaaagcacccaatca
tttaatgacttcactcgggttgttggtggagaagatgccaaaccaggtcaattcccttgg
caggttgttttgaatggtaaagttgatgcattctgtggaggctctatcgttaatgaaaaa
tggattgtaactgctgcccactgtgttgaaactggtgttaaaattacagttgtcgcaggt
gaacataatattgaggagacagaacatacagagcaaaagcgaaatgtgattcgaattatt
cctcaccacaactacaatgcagctattaataagtacaaccatgacattgcccttctggaa
ctggacgaacccttagtgctaaacagctacgttacacctatttgcattgctgacaaggaa
tacacgaacatcttcctcaaatttggatctggctatgtaagtggctggggaagagtcttc
cacaaagggagatcagctttagttcttcagtaccttagagttccacttgttgaccgagcc
acatgtcttcgatctacaaagttcaccatctataacaacatgttctgtgctggcttccat
gaaggaggtagagattcatgtcaaggagatagtgggggaccccatgttactgaagtggaa
gggaccagtttcttaactggaattattagctggggtgaagagtgtgcaatgaaaggcaaa
tatggaatatataccaaggtatcccggtatgtcaactggattaaggaaaaaacaaagctc
acttaa
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