KEGG T01001: 223

Homo sapiens (human): 223

Entry

223               CDS       T01001

Symbol

ALDH9A1, ALDH4, ALDH7, ALDH9, E3, TMABA-DH, TMABADH, TMABALDH

Name

(RefSeq) aldehyde dehydrogenase 9 family member A1

K00149

aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]

Organism

hsa Homo sapiens (human)

Pathway

hsa00010

Glycolysis / Gluconeogenesis

hsa00053

Ascorbate and aldarate metabolism

hsa00071

Fatty acid degradation

hsa00280

Valine, leucine and isoleucine degradation

hsa00310

Lysine degradation

hsa00330

Arginine and proline metabolism

hsa00340

Histidine metabolism

hsa00380

Tryptophan metabolism

hsa00410

beta-Alanine metabolism

hsa00561

Glycerolipid metabolism

hsa00620

Pyruvate metabolism

hsa01100

Metabolic pathways

hsa04936

Alcoholic liver disease

Module

hsa_M00135

GABA biosynthesis, eukaryotes, putrescine => GABA

Brite

KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    223 (ALDH9A1)
   00053 Ascorbate and aldarate metabolism
    223 (ALDH9A1)
   00620 Pyruvate metabolism
    223 (ALDH9A1)
  09103 Lipid metabolism
   00071 Fatty acid degradation
    223 (ALDH9A1)
   00561 Glycerolipid metabolism
    223 (ALDH9A1)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    223 (ALDH9A1)
   00310 Lysine degradation
    223 (ALDH9A1)
   00330 Arginine and proline metabolism
    223 (ALDH9A1)
   00340 Histidine metabolism
    223 (ALDH9A1)
   00380 Tryptophan metabolism
    223 (ALDH9A1)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    223 (ALDH9A1)
09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    223 (ALDH9A1)
Enzymes [BR:hsa01000]
1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.3  aldehyde dehydrogenase (NAD+)
     223 (ALDH9A1)
    1.2.1.47  4-trimethylammoniobutyraldehyde dehydrogenase
     223 (ALDH9A1)

SSDB

Motif

Pfam:

Aldedh DUF1487

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

1:complement(165662216..165698562)

AA seq 518 aa
MFLRAGLAALSPLLRSLRPSPVAAMSTGTFVVSQPLNYRGGARVEPADASGTEKAFEPAT
GRVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERCRILLEAARIIREREDEIATMEC
INNGKSIFEARLDIDISWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAW
NYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLFNVVQGGAATG
QFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIFSDCDMNNAVKGA
LMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHL
ERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPV
MSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQAGTCFINNYNVSPVELP
FGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF

NT seq 1557 nt +upstreamnt +downstreamnt
atgtttctccgagcaggcctggccgcgctctccccgcttcttcgcagtcttcggccctct
cctgtcgccgccatgagcactggcaccttcgtcgtgtcgcagccgctcaattaccgcggc
ggggcccgcgtggagccggcggacgcctccggtaccgagaaagctttcgagccagcaacc
ggccgagtgatagctactttcacatgttcaggagaaaaggaagtaaatttggctgttcaa
aatgcaaaggctgcttttaaaatatggagtcaaaaatctggcatggagcgttgccgaatc
cttttggaggctgccaggataataagggaacgggaggatgaaattgctactatggagtgc
atcaacaatggcaagtccatctttgaggcccgcttggacattgacatttcctggcagtgc
ctggagtattatgcgggcttggctgcatccatggctggtgaacacatccagctcccaggt
ggatcgtttggttataccagaagagaaccacttggggtatgtgtgggaataggagcatgg
aactacccctttcagattgcctcttggaagtcggctccagcattagcctgtggtaatgcc
atggtctttaaaccttctccctttacacctgtttctgcattgctactggctgaaatctac
agtgaggctggtgtacctcctgggctcttcaatgtggtgcagggaggggctgccacaggc
cagtttctgtgtcagcatcccgatgtggccaaagtctccttcactggaagtgtgcccact
ggcatgaagatcatggagatgtcagctaaaggaatcaaacctgttaccttggaacttgga
ggcaaatctccactcatcatcttctcagactgtgatatgaacaatgctgtaaagggggcg
ctgatggccaacttcctcacacaaggccaggtttgctgtaatggcacaagagtatttgtg
cagaaagaaattcttgataaatttacagaggaagtggtgaaacagacccaaaggattaaa
attggagatccccttctggaagatacaaggatgggtccactcatcaaccgaccacacctg
gagcgagtccttgggtttgtcaaagtggcaaaggagcagggtgctaaagtgttatgtggt
ggagatatatatgtacctgaagatcccaaattaaaggatggatattacatgagaccttgt
gtattaactaattgcagagacgacatgacctgtgtgaaggaagagatctttgggcctgtt
atgtccattttatcatttgacactgaagctgaggttctagaaagagccaatgataccact
tttggactagcagctggcgtctttaccagggacatccaacgggctcatagagtggtagct
gagcttcaggctgggacgtgcttcattaacaactataacgtcagcccagtggagttgccc
tttggtggatataagaagtcaggatttggcagagagaacggccgtgtgacaatcgaatat
tattcacagctgaagactgtgtgtgtggagatgggtgatgtggaatctgctttttga

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