KEGG   Homo sapiens (human): 2243Help
Entry
2243              CDS       T01001                                 

Gene name
FGA, Fib2
Definition
(RefSeq) fibrinogen alpha chain
  KO
K03903  fibrinogen alpha chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04610  Complement and coagulation cascades
hsa04611  Platelet activation
Disease
H00222  Afibrinogenemia
H00223  Inherited thrombophilia
H00845  Familial amyloidosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    2243 (FGA)
   04611 Platelet activation
    2243 (FGA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2243 (FGA)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    2243 (FGA)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   2243 (FGA)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   2243 (FGA)
 Hyaluronan
  Extracellular matrix or blood plasma proteins
   2243 (FGA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Fibrinogen_C Fib_alpha Fibrinogen_aC ORF6C
Motif
Other DBs
NCBI-GeneID: 2243
NCBI-ProteinID: NP_000499
OMIM: 134820
HGNC: 3661
Ensembl: ENSG00000171560
Vega: OTTHUMG00000150330
Pharos: P02671(Tbio)
CPD: C00952
UniProt: P02671
LinkDB All DBs
Structure
PDB: 

Position
4q31.3
AA seq 866 aa AA seqDB search
MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW
NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA
NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC
RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ
LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS
GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW
NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV
SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK
EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF
VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS
YKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFS
VYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQR
GSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSH
NNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENG
VVWVSFRGADYSLRAVRMKIRPLVTQ
NT seq 2601 nt NT seq  +upstreamnt  +downstreamnt
atgttttccatgaggatcgtctgcctggtcctaagtgtggtgggcacagcatggactgca
gatagtggtgaaggtgactttctagctgaaggaggaggcgtgcgtggcccaagggttgtg
gaaagacatcaatctgcctgcaaagattcagactggcccttctgctctgatgaagactgg
aactacaaatgcccttctggctgcaggatgaaagggttgattgatgaagtcaatcaagat
tttacaaacagaataaataagctcaaaaattcactatttgaatatcagaagaacaataag
gattctcattcgttgaccactaatataatggaaattttgagaggcgatttttcctcagcc
aataaccgtgataatacctacaaccgagtgtcagaggatctgagaagcagaattgaagtc
ctgaagcgcaaagtcatagaaaaagtacagcatatccagcttctgcagaaaaatgttaga
gctcagttggttgatatgaaacgactggaggtggacattgatattaagatccgatcttgt
cgagggtcatgcagtagggctttagctcgtgaagtagatctgaaggactatgaagatcag
cagaagcaacttgaacaggtcattgccaaagacttacttccctctagagataggcaacac
ttaccactgataaaaatgaaaccagttccagacttggttcccggaaattttaagagccag
cttcagaaggtacccccagagtggaaggcattaacagacatgccgcagatgagaatggag
ttagagagacctggtggaaatgagattactcgaggaggctccacctcttatggaaccgga
tcagagacggaaagccccaggaaccctagcagtgctggaagctggaactctgggagctct
ggacctggaagtactggaaaccgaaaccctgggagctctgggactggagggactgcaacc
tggaaacctgggagctctggacctggaagtactggaagctggaactctgggagctctgga
actggaagtactggaaaccaaaaccctgggagccctagacctggtagtaccggaacctgg
aatcctggcagctctgaacgcggaagtgctgggcactggacctctgagagctctgtatct
ggtagtactggacaatggcactctgaatctggaagttttaggccagatagcccaggctct
gggaacgcgaggcctaacaacccagactggggcacatttgaagaggtgtcaggaaatgta
agtccagggacaaggagagagtaccacacagaaaaactggtcacttctaaaggagataaa
gagctcaggactggtaaagagaaggtcacctctggtagcacaaccaccacgcgtcgttca
tgctctaaaaccgttactaagactgttattggtcctgatggtcacaaagaagttaccaaa
gaagtggtgacctccgaagatggttctgactgtcccgaggcaatggatttaggcacattg
tctggcataggtactctggatgggttccgccataggcaccctgatgaagctgccttcttc
gacactgcctcaactggaaaaacattcccaggtttcttctcacctatgttaggagagttt
gtcagtgagactgagtctaggggctcagaatctggcatcttcacaaatacaaaggaatcc
agttctcatcaccctgggatagctgaattcccttcccgtggtaaatcttcaagttacagc
aaacaatttactagtagcacgagttacaacagaggagactccacatttgaaagcaagagc
tataaaatggcagatgaggccggaagtgaagccgatcatgaaggaacacatagcaccaag
agaggccatgctaaatctcgccctgtcagagactgtgatgatgtcctccaaacacatcct
tcaggtacccaaagtggcattttcaatatcaagctaccgggatccagtaagattttttct
gtttattgcgatcaagagaccagtttgggaggatggcttttgatccagcaaagaatggat
ggatcactgaattttaaccggacctggcaagactacaagagaggtttcggcagcctgaat
gacgagggggaaggagaattctggctaggcaatgactacctccacttactaacccaaagg
ggctctgttcttagggttgaattagaggactgggctgggaatgaagcttatgcagaatat
cacttccgggtaggctctgaggctgaaggctatgccctccaagtctcctcctatgaaggc
actgcgggtgatgctctgattgagggttccgtagaggaaggggcagagtacacctctcac
aacaacatgcagttcagcacctttgacagggatgcagaccagtgggaagagaactgtgca
gaagtctatgggggaggctggtggtataataactgccaagcagccaatctcaatggaatc
tactaccctgggggctcctatgacccaaggaataacagtccttatgagattgagaatgga
gtggtctgggtttcctttagaggggcagattattccctcagggctgttcgcatgaaaatt
aggccccttgtgacccaatag

KEGG   Homo sapiens (human): 2244Help
Entry
2244              CDS       T01001                                 

Gene name
FGB, HEL-S-78p
Definition
(RefSeq) fibrinogen beta chain
  KO
K03904  fibrinogen beta chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04610  Complement and coagulation cascades
hsa04611  Platelet activation
Disease
H00222  Afibrinogenemia
H00223  Inherited thrombophilia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    2244 (FGB)
   04611 Platelet activation
    2244 (FGB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2244 (FGB)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    2244 (FGB)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   2244 (FGB)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   2244 (FGB)
 Hyaluronan
  Extracellular matrix or blood plasma proteins
   2244 (FGB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Fibrinogen_C Fib_alpha UPF0242 CALCOCO1 DUF745 SF-assemblin
Motif
Other DBs
NCBI-GeneID: 2244
NCBI-ProteinID: NP_005132
OMIM: 134830
HGNC: 3662
Ensembl: ENSG00000171564
Vega: OTTHUMG00000150331
Pharos: P02675(Tbio)
CPD: C02404
UniProt: P02675 V9HVY1
LinkDB All DBs
Structure
PDB: 

Position
4q31.3
AA seq 491 aa AA seqDB search
MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLR
PAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQE
RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ
LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE
CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK
QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT
VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP
RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM
SMKIRPFFPQQ
NT seq 1476 nt NT seq  +upstreamnt  +downstreamnt
atgaaaaggatggtttcttggagcttccacaaacttaaaaccatgaaacatctattattg
ctactattgtgtgtttttctagttaagtcccaaggtgtcaacgacaatgaggagggtttc
ttcagtgcccgtggtcatcgaccccttgacaagaagagagaagaggctcccagcctgagg
cctgccccaccgcccatcagtggaggtggctatcgggctcgtccagccaaagcagctgcc
actcaaaagaaagtagaaagaaaagcccctgatgctggaggctgtcttcacgctgaccca
gacctgggggtgttgtgtcctacaggatgtcagttgcaagaggctttgctacaacaggaa
aggccaatcagaaatagtgttgatgagttaaataacaatgtggaagctgtttcccagacc
tcctcttcttcctttcagtacatgtatttgctgaaagacctgtggcaaaagaggcagaag
caagtaaaagataatgaaaatgtagtcaatgagtactcctcagaactggaaaagcaccaa
ttatatatagatgagactgtgaatagcaatatcccaactaaccttcgtgtgcttcgttca
atcctggaaaacctgagaagcaaaatacaaaagttagaatctgatgtctcagctcaaatg
gaatattgtcgcaccccatgcactgtcagttgcaatattcctgtggtgtctggcaaagaa
tgtgaggaaattatcaggaaaggaggtgaaacatctgaaatgtatctcattcaacctgac
agttctgtcaaaccgtatagagtatactgtgacatgaatacagaaaatggaggatggaca
gtgattcagaaccgtcaagacggtagtgttgactttggcaggaaatgggatccatataaa
cagggatttggaaatgttgcaaccaacacagatgggaagaattactgtggcctaccaggt
gaatattggcttggaaatgataaaattagccagcttaccaggatgggacccacagaactt
ttgatagaaatggaggactggaaaggagacaaagtaaaggctcactatggaggattcact
gtacagaatgaagccaacaaataccagatctcagtgaacaaatacagaggaacagccggt
aatgccctcatggatggagcatctcagctgatgggagaaaacaggaccatgaccattcac
aacggcatgttcttcagcacgtatgacagagacaatgacggctggttaacatcagatccc
agaaaacagtgttctaaagaagacggtggtggatggtggtataatagatgtcatgcagcc
aatccaaacggcagatactactggggtggacagtacacctgggacatggcaaagcatggc
acagatgatggtgtagtatggatgaattggaaggggtcatggtactcaatgaggaagatg
agtatgaagatcaggcccttcttcccacagcaatag

KEGG   Homo sapiens (human): 2266Help
Entry
2266              CDS       T01001                                 

Gene name
FGG
Definition
(RefSeq) fibrinogen gamma chain
  KO
K03905  fibrinogen gamma chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04610  Complement and coagulation cascades
hsa04611  Platelet activation
hsa05150  Staphylococcus aureus infection
Disease
H00222  Afibrinogenemia
H00223  Inherited thrombophilia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    2266 (FGG)
   04611 Platelet activation
    2266 (FGG)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    2266 (FGG)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2266 (FGG)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    2266 (FGG)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   2266 (FGG)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   2266 (FGG)
 Hyaluronan
  Extracellular matrix or blood plasma proteins
   2266 (FGG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Fibrinogen_C Fib_alpha Syntaxin Spc7 CEP209_CC5 TMF_DNA_bd
Motif
Other DBs
NCBI-GeneID: 2266
NCBI-ProteinID: NP_068656
OMIM: 134850
HGNC: 3694
Ensembl: ENSG00000171557
Vega: OTTHUMG00000150329
Pharos: P02679(Tbio)
UniProt: P02679
LinkDB All DBs
Structure
PDB: 

Position
4q32.1
AA seq 453 aa AA seqDB search
MSWSLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQT
KVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIM
KYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQ
DIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEG
FGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKY
RLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGW
WMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
GEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
NT seq 1362 nt NT seq  +upstreamnt  +downstreamnt
atgagttggtccttgcacccccggaatttaattctctacttctatgctcttttatttctc
tcttcaacatgtgtagcatatgttgctaccagagacaactgctgcatcttagatgaaaga
ttcggtagttattgtccaactacctgtggcattgcagatttcctgtctacttatcaaacc
aaagtagacaaggatctacagtctttggaagacatcttacatcaagttgaaaacaaaaca
tcagaagtcaaacagctgataaaagcaatccaactcacttataatcctgatgaatcatca
aaaccaaatatgatagacgctgctactttgaagtccaggaaaatgttagaagaaattatg
aaatatgaagcatcgattttaacacatgactcaagtattcgatatttgcaggaaatatat
aattcaaataatcaaaagattgttaacctgaaagagaaggtagcccagcttgaagcacag
tgccaggaaccttgcaaagacacggtgcaaatccatgatatcactgggaaagattgtcaa
gacattgccaataagggagctaaacagagcgggctttactttattaaacctctgaaagct
aaccagcaattcttagtctactgtgaaatcgatgggtctggaaatggatggactgtgttt
cagaagagacttgatggcagtgtagatttcaagaaaaactggattcaatataaagaagga
tttggacatctgtctcctactggcacaacagaattttggctgggaaatgagaagattcat
ttgataagcacacagtctgccatcccatatgcattaagagtggaactggaagactggaat
ggcagaaccagtactgcagactatgccatgttcaaggtgggacctgaagctgacaagtac
cgcctaacatatgcctacttcgctggtggggatgctggagatgcctttgatggctttgat
tttggcgatgatcctagtgacaagtttttcacatcccataatggcatgcagttcagtacc
tgggacaatgacaatgataagtttgaaggcaactgtgctgaacaggatggatctggttgg
tggatgaacaagtgtcacgctggccatctcaatggagtttattaccaaggtggcacttac
tcaaaagcatctactcctaatggttatgataatggcattatttgggccacttggaaaacc
cggtggtattccatgaagaaaaccactatgaagataatcccattcaacagactcacaatt
ggagaaggacagcaacaccacctggggggagccaaacaggtcagaccagagcaccctgcg
gaaacagaatatgactcactttaccctgaggatgatttgtag

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