KEGG   Homo sapiens (human): 2277
Entry
2277              CDS       T01001                                 

Gene name
VEGFD, FIGF, VEGF-D
Definition
(RefSeq) vascular endothelial growth factor D
  KO
K05449  vascular endothelial growth factor C/D
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04020  Calcium signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04668  TNF signaling pathway
hsa04926  Relaxin signaling pathway
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    2277 (VEGFD)
   04014 Ras signaling pathway
    2277 (VEGFD)
   04015 Rap1 signaling pathway
    2277 (VEGFD)
   04668 TNF signaling pathway
    2277 (VEGFD)
   04020 Calcium signaling pathway
    2277 (VEGFD)
   04151 PI3K-Akt signaling pathway
    2277 (VEGFD)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    2277 (VEGFD)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    2277 (VEGFD)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2277 (VEGFD)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    2277 (VEGFD)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:hsa04052]
    2277 (VEGFD)
Cytokines and growth factors [BR:hsa04052]
 Growth factors
  Growth factors (RTK binding)
   2277 (VEGFD)
SSDB
Motif
Pfam: PDGF CXCXC
Other DBs
NCBI-GeneID: 2277
NCBI-ProteinID: NP_004460
OMIM: 300091
HGNC: 3708
Ensembl: ENSG00000165197
Vega: OTTHUMG00000021175
Pharos: O43915(Tbio)
UniProt: O43915
LinkDB
Structure
PDB: 
2XV7

Position
Xp22.2
AA seq 354 aa
MYREWVVVNVFMMLYVQLVQGSSNEHGPVKRSSQSTLERSEQQIRAASSLEELLRITHSE
DWKLWRCRLRLKSFTSMDSRSASHRSTRFAATFYDIETLKVIDEEWQRTQCSPRETCVEV
ASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPELVP
VKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCSHSKKLCPIDMLWDSNKCKCVLQEE
NPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNCSCFECKESLETC
CQKHKLFHPDTCSCEDRCPFHTRPCASGKTACAKHCRFPKEKRAAQGPHSRKNP
NT seq 1065 nt   +upstreamnt  +downstreamnt
atgtacagagagtgggtagtggtgaatgttttcatgatgttgtacgtccagctggtgcag
ggctccagtaatgaacatggaccagtgaagcgatcatctcagtccacattggaacgatct
gaacagcagatcagggctgcttctagtttggaggaactacttcgaattactcactctgag
gactggaagctgtggagatgcaggctgaggctcaaaagttttaccagtatggactctcgc
tcagcatcccatcggtccactaggtttgcggcaactttctatgacattgaaacactaaaa
gttatagatgaagaatggcaaagaactcagtgcagccctagagaaacgtgcgtggaggtg
gccagtgagctggggaagagtaccaacacattcttcaagcccccttgtgtgaacgtgttc
cgatgtggtggctgttgcaatgaagagagccttatctgtatgaacaccagcacctcgtac
atttccaaacagctctttgagatatcagtgcctttgacatcagtacctgaattagtgcct
gttaaagttgccaatcatacaggttgtaagtgcttgccaacagccccccgccatccatac
tcaattatcagaagatccatccagatccctgaagaagatcgctgttcccattccaagaaa
ctctgtcctattgacatgctatgggatagcaacaaatgtaaatgtgttttgcaggaggaa
aatccacttgctggaacagaagaccactctcatctccaggaaccagctctctgtgggcca
cacatgatgtttgacgaagatcgttgcgagtgtgtctgtaaaacaccatgtcccaaagat
ctaatccagcaccccaaaaactgcagttgctttgagtgcaaagaaagtctggagacctgc
tgccagaagcacaagctatttcacccagacacctgcagctgtgaggacagatgccccttt
cataccagaccatgtgcaagtggcaaaacagcatgtgcaaagcattgccgctttccaaag
gagaaaagggctgcccaggggccccacagccgaaagaatccttga

KEGG   Homo sapiens (human): 7424
Entry
7424              CDS       T01001                                 

Gene name
VEGFC, Flt4-L, LMPH1D, LMPHM4, VRP
Definition
(RefSeq) vascular endothelial growth factor C
  KO
K05449  vascular endothelial growth factor C/D
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04020  Calcium signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04668  TNF signaling pathway
hsa04926  Relaxin signaling pathway
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa05200  Pathways in cancer
Disease
H00535  Hereditary lymphedema
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    7424 (VEGFC)
   04014 Ras signaling pathway
    7424 (VEGFC)
   04015 Rap1 signaling pathway
    7424 (VEGFC)
   04668 TNF signaling pathway
    7424 (VEGFC)
   04020 Calcium signaling pathway
    7424 (VEGFC)
   04151 PI3K-Akt signaling pathway
    7424 (VEGFC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    7424 (VEGFC)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    7424 (VEGFC)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    7424 (VEGFC)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    7424 (VEGFC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:hsa04052]
    7424 (VEGFC)
Cytokines and growth factors [BR:hsa04052]
 Growth factors
  Growth factors (RTK binding)
   7424 (VEGFC)
SSDB
Motif
Pfam: PDGF CXCXC
Other DBs
NCBI-GeneID: 7424
NCBI-ProteinID: NP_005420
OMIM: 601528
HGNC: 12682
Ensembl: ENSG00000150630
Vega: OTTHUMG00000160734
Pharos: P49767(Tbio)
UniProt: P49767
LinkDB
Structure
PDB: 
2X1W 2X1X 4BSK

Position
4q34.3
AA seq 419 aa
MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATAYASKDLEEQL
RSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLNSRTEETIKFAAAHYNTEILK
SIDNEWRKTQCMPREVCIDVGKEFGVATNTFFKPPCVSVYRCGGCCNSEGLQCMNTSTSY
LSKTLFEITVPLSQGPKPVTISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAAN
KTCPTNYMWNNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLR
PASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRNQPLNPGKCAC
ECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGFSYSEEVCRCVPSYWKRPQMS
NT seq 1260 nt   +upstreamnt  +downstreamnt
atgcacttgctgggcttcttctctgtggcgtgttctctgctcgccgctgcgctgctcccg
ggtcctcgcgaggcgcccgccgccgccgccgccttcgagtccggactcgacctctcggac
gcggagcccgacgcgggcgaggccacggcttatgcaagcaaagatctggaggagcagtta
cggtctgtgtccagtgtagatgaactcatgactgtactctacccagaatattggaaaatg
tacaagtgtcagctaaggaaaggaggctggcaacataacagagaacaggccaacctcaac
tcaaggacagaagagactataaaatttgctgcagcacattataatacagagatcttgaaa
agtattgataatgagtggagaaagactcaatgcatgccacgggaggtgtgtatagatgtg
gggaaggagtttggagtcgcgacaaacaccttctttaaacctccatgtgtgtccgtctac
agatgtgggggttgctgcaatagtgaggggctgcagtgcatgaacaccagcacgagctac
ctcagcaagacgttatttgaaattacagtgcctctctctcaaggccccaaaccagtaaca
atcagttttgccaatcacacttcctgccgatgcatgtctaaactggatgtttacagacaa
gttcattccattattagacgttccctgccagcaacactaccacagtgtcaggcagcgaac
aagacctgccccaccaattacatgtggaataatcacatctgcagatgcctggctcaggaa
gattttatgttttcctcggatgctggagatgactcaacagatggattccatgacatctgt
ggaccaaacaaggagctggatgaagagacctgtcagtgtgtctgcagagcggggcttcgg
cctgccagctgtggaccccacaaagaactagacagaaactcatgccagtgtgtctgtaaa
aacaaactcttccccagccaatgtggggccaaccgagaatttgatgaaaacacatgccag
tgtgtatgtaaaagaacctgccccagaaatcaacccctaaatcctggaaaatgtgcctgt
gaatgtacagaaagtccacagaaatgcttgttaaaaggaaagaagttccaccaccaaaca
tgcagctgttacagacggccatgtacgaaccgccagaaggcttgtgagccaggattttca
tatagtgaagaagtgtgtcgttgtgtcccttcatattggaaaagaccacaaatgagctaa

DBGET integrated database retrieval system