KEGG   Homo sapiens (human): 22808
Entry
22808             CDS       T01001                                 
Symbol
MRAS, M-RAs, NS11, R-RAS3, RRAS3
Name
(RefSeq) muscle RAS oncogene homolog
  KO
K07831  Ras-related protein M-Ras
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04072  Phospholipase D signaling pathway
hsa04137  Mitophagy - animal
hsa04140  Autophagy - animal
hsa04218  Cellular senescence
hsa04371  Apelin signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04810  Regulation of actin cytoskeleton
hsa05205  Proteoglycans in cancer
Network
nt06526  MAPK signaling
  Element
N01598  Regulation of GF-RTK-RAS-ERK signaling, MRAS-SHOC2-PP1 holophosphatase
Disease
H01738  Noonan syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    22808 (MRAS)
   04014 Ras signaling pathway
    22808 (MRAS)
   04015 Rap1 signaling pathway
    22808 (MRAS)
   04371 Apelin signaling pathway
    22808 (MRAS)
   04072 Phospholipase D signaling pathway
    22808 (MRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    22808 (MRAS)
   04137 Mitophagy - animal
    22808 (MRAS)
  09143 Cell growth and death
   04218 Cellular senescence
    22808 (MRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    22808 (MRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    22808 (MRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    22808 (MRAS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:hsa04031]
    22808 (MRAS)
GTP-binding proteins [BR:hsa04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    22808 (MRAS)
SSDB
Motif
Pfam: Ras Roc GTP_EFTU Arf RsgA_GTPase MMR_HSR1 ATP_bind_1 AAA_16 MMR_HSR1_Xtn
Other DBs
NCBI-GeneID: 22808
NCBI-ProteinID: NP_001078518
OMIM: 608435
HGNC: 7227
Ensembl: ENSG00000158186
UniProt: O14807 Q6FGP0 Q8WVM9
Structure
LinkDB
Position
3:138347648..138405535
AA seq 208 aa
MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQW
AILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFP
MILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQIP
EKSQKKKKKTKWRGDRATGTHKLQCVIL
NT seq 627 nt   +upstreamnt  +downstreamnt
atggcaaccagcgccgtccccagtgacaacctccccacatacaagctggtggtggtgggg
gatgggggtgtgggcaaaagtgccctcaccatccagtttttccagaagatctttgtgcct
gactatgaccccaccattgaagactcctacctgaaacatacggagattgacaatcaatgg
gccatcttggacgttctggacacagctgggcaggaggaattcagcgccatgcgggagcaa
tacatgcgcacgggggatggcttcctcatcgtctactccgtcactgacaaggccagcttt
gagcacgtggaccgcttccaccagcttatcctgcgcgtcaaagacagggagtcattcccg
atgatcctcgtggccaacaaggtcgatttgatgcacttgaggaagatcaccagggagcaa
ggaaaagaaatggcgaccaaacacaatattccgtacatagaaaccagtgccaaggaccca
cctctcaatgtcgacaaagccttccatgacctcgttagagtaattaggcaacagattccg
gaaaaaagccagaagaagaagaagaaaaccaaatggcggggagaccgggccacaggcacc
cacaaactgcaatgtgtgatcttgtga

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