KEGG   Homo sapiens (human): 22953
Entry
22953             CDS       T01001                                 

Gene name
P2RX2, DFNA41, P2X2
Definition
(RefSeq) purinergic receptor P2X 2
  KO
K05216  P2X purinoceptor 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04742  Taste transduction
Disease
H00604  Deafness, autosomal dominant
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    22953 (P2RX2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    22953 (P2RX2)
 09150 Organismal Systems
  09157 Sensory system
   04742 Taste transduction
    22953 (P2RX2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    22953 (P2RX2)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   22953 (P2RX2)
SSDB
Motif
Pfam: P2X_receptor WAP
Other DBs
NCBI-GeneID: 22953
NCBI-ProteinID: NP_733782
OMIM: 600844
HGNC: 15459
Ensembl: ENSG00000187848
Vega: OTTHUMG00000168018
Pharos: Q9UBL9(Tbio)
UniProt: Q9UBL9 Q32MC3
LinkDB
Position
12q24.33
AA seq 471 aa
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ
TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD
WILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSG
QEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
NT seq 1416 nt   +upstreamnt  +downstreamnt
atggccgccgcccagcccaagtaccccgccggggcgaccgcccggcgcctggcccggggc
tgctggtccgccctctgggactacgagacgcccaaggtgatcgtggtgaggaaccggcgc
ctgggggtcctgtaccgcgccgtgcagctgctcatcctgctctacttcgtgtggtacgta
ttcatcgtgcagaaaagctaccaggagagcgagacgggccccgagagctccatcatcacc
aaggtcaaggggatcaccacgtccgagcacaaagtgtgggacgtggaggagtacgtgaag
ccccccgaggggggcagcgtgttcagcatcatcaccagggtcgaggccacccactcccag
acccagggaacctgccccgagagcataagggtccacaacgccacctgcctctccgacgcc
gactgcgtggctggggagctggacatgctgggaaacggcctgaggactgggcgctgtgtg
ccctattaccaggggccctccaagacctgcgaggtgttcggctggtgcccggtggaagat
ggggcctctgtcagccaatttctgggtacgatggccccaaatttcaccatcctcatcaag
aacagcatccactaccccaaattccacttctccaagggcaacatcgccgaccgcacagac
gggtacctgaagcgctgcacgttccacgaggcctccgacctctactgccccatcttcaag
ctgggctttatcgtggagaaggctggggagagcttcacagagctcgcacacaagggtggt
gtcatcggggtcattatcaactgggactgtgacctggacctgcctgcatcggagtgcaac
cccaagtactccttccggaggcttgaccccaagcacgtgcctgcctcgtcaggctacaac
ttcaggtttgccaaatactacaagatcaatggcaccaccacccgcacgctcatcaaggcc
tacgggatccgcattgacgtcattgtgcatggacaggccgggaagttcagcctgattccc
accattattaatctggccacagctctgacttccgtcggggtgggctccttcctgtgcgac
tggatcttgctaacattcatgaacaaaaacaaggtctacagccataagaaatttgacaag
gtgtgtacgccgagccacccctcaggtagctggcctgtgacccttgcccgtgtattgggc
caggcccctcccgaacccggccaccgctccgaggaccagcaccccagccctccatcaggc
caggagggccaacaaggggcagagtgtggcccagccttcccgcccctgcggccttgcccc
atctctgccccttctgagcagatggtggacactcctgcctccgagcctgcccaagcctcc
acacccacagaccccaaaggtttggctcaactctga

KEGG   Homo sapiens (human): 5023
Entry
5023              CDS       T01001                                 

Gene name
P2RX1, P2X1
Definition
(RefSeq) purinergic receptor P2X 1
  KO
K05215  P2X purinoceptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04611  Platelet activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    5023 (P2RX1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5023 (P2RX1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    5023 (P2RX1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    5023 (P2RX1)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   5023 (P2RX1)
SSDB
Motif
Pfam: P2X_receptor
Other DBs
NCBI-GeneID: 5023
NCBI-ProteinID: NP_002549
OMIM: 600845
HGNC: 8533
Ensembl: ENSG00000108405
Vega: OTTHUMG00000177673
Pharos: P51575(Tchem)
UniProt: P51575
LinkDB
Position
17p13.2
AA seq 399 aa
MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSG
LISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEH
PEGGICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLR
EAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESG
QNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNLSPGFNFRFARHFVEN
GTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKR
HYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENMRTS
NT seq 1200 nt   +upstreamnt  +downstreamnt
atggcacggcggttccaggaggagctggccgccttcctcttcgagtatgacaccccccgc
atggtgctggtgcgtaataagaaggtgggcgttatcttccgactgatccagctggtggtc
ctggtctacgtcatcgggtgggtgtttctctatgagaagggctaccagacctcgagcggc
ctcatcagcagtgtctctgtgaaactcaagggcctggccgtgacccagctccctggcctc
ggcccccaggtctgggatgtggctgactacgtcttcccagcccagggggacaactccttc
gtggtcatgaccaatttcatcgtgaccccgaagcagactcaaggctactgcgcagagcac
ccagaagggggcatatgcaaggaagacagtggctgtacccctgggaaggccaagaggaag
gcccaaggcatccgcacgggcaagtgtgtggccttcaacgacactgtgaagacgtgtgag
atctttggctggtgccccgtggaggtggatgacgacatcccgcgccctgcccttctccga
gaggccgagaacttcactcttttcatcaagaacagcatcagctttccacgcttcaaggtc
aacaggcgcaacctggtggaggaggtgaatgctgcccacatgaagacctgcctctttcac
aagaccctgcaccccctgtgcccagtcttccagcttggctacgtggtgcaagagtcaggc
cagaacttcagcaccctggctgagaagggtggagtggttggcatcaccatcgactggcac
tgtgacctggactggcacgtacggcactgcagacccatctatgagttccatgggctgtac
gaagagaaaaatctctccccaggcttcaacttcaggtttgccaggcactttgtggagaac
gggaccaactaccgtcacctcttcaaggtgtttgggattcgctttgacatcctggtggac
ggcaaggccgggaagtttgacatcatccctacaatgaccaccatcggctctggaattggc
atctttggggtggccacagttctctgtgacctgctgctgcttcacatcctgcctaagagg
cactactacaagcagaagaagttcaaatacgctgaggacatggggccaggggcggctgag
cgtgacctcgcagctaccagctccaccctgggcctgcaggagaacatgaggacatcctga

KEGG   Homo sapiens (human): 5024
Entry
5024              CDS       T01001                                 

Gene name
P2RX3, P2X3
Definition
(RefSeq) purinergic receptor P2X 3
  KO
K05217  P2X purinoceptor 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04742  Taste transduction
Drug target
Gefapixant (DG03083): D11349 D11693
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    5024 (P2RX3)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5024 (P2RX3)
 09150 Organismal Systems
  09157 Sensory system
   04742 Taste transduction
    5024 (P2RX3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    5024 (P2RX3)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   5024 (P2RX3)
SSDB
Motif
Pfam: P2X_receptor
Other DBs
NCBI-GeneID: 5024
NCBI-ProteinID: NP_002550
OMIM: 600843
HGNC: 8534
Ensembl: ENSG00000109991
Vega: OTTHUMG00000167025
Pharos: P56373(Tchem)
UniProt: P56373
LinkDB
Structure
PDB: 

Position
11q12.1
AA seq 397 aa
MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDS
QCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEE
VNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH
NT seq 1194 nt   +upstreamnt  +downstreamnt
atgaactgcatatccgacttcttcacctatgagaccaccaagtcggtggttgtgaagagc
tggaccatcgggatcatcaaccgagtagttcagcttctgatcatctcctactttgtaggg
tgggttttcttgcacgagaaggcttaccaggtacgggacacagccattgagtcctcggtg
gtaaccaaggtgaagggctccggactctacgccaacagagtcatggatgtgtctgattac
gtgacgccacctcagggcacctcggtctttgtcatcatcaccaagatgattgttactgaa
aatcagatgcaaggattctgcccagagagtgaggagaaataccgctgtgtatcagacagc
cagtgcgggcctgagcgcttgccaggtggggggatcctcactggccgctgcgtgaactac
agctctgtgctccggacctgtgagatccagggctggtgccccacggaggtggacacagtg
gaaacgcccatcatgatggaagctgagaacttcactattttcatcaagaacagcatccgt
ttccccctcttcaactttgagaagggaaacctccttcccaacctgacagccagggacatg
aagacctgccgcttccacccggacaaggaccctttctgccccatcttgcgggtaggggac
gtggtcaagtttgcggggcaggattttgccaaactggcgcgcacggggggagttctgggc
attaagatcggctgggtgtgcgacttggacaaggcctgggaccagtgcatccccaaatac
tccttcacccggctcgacagcgtttctgagaaaagcagcgtgtccccaggctacaacttc
aggtttgccaagtactacaaaatggaaaatggcagtgagtaccgcaccctcctgaaggct
tttggcatccgcttcgacgtgctggtatacgggaatgctggcaagttcaacatcatcccc
accatcatcagctctgtggcggcctttacttctgtgggagtgggaactgttctctgtgac
atcatcctgctcaacttcctcaagggggccgaccagtacaaagccaagaagtttgaggag
gtgaatgagactacgctgaaaatcgcggctttgaccaacccagtgtaccccagcgaccag
accacagcggagaagcagtccaccgattcgggggccttctccataggccactag

KEGG   Homo sapiens (human): 5025
Entry
5025              CDS       T01001                                 

Gene name
P2RX4, P2X4, P2X4R
Definition
(RefSeq) purinergic receptor P2X 4
  KO
K05218  P2X purinoceptor 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    5025 (P2RX4)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5025 (P2RX4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    5025 (P2RX4)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   5025 (P2RX4)
SSDB
Motif
Pfam: P2X_receptor DUF3624
Other DBs
NCBI-GeneID: 5025
NCBI-ProteinID: NP_002551
OMIM: 600846
HGNC: 8535
Ensembl: ENSG00000135124
Vega: OTTHUMG00000169155
Pharos: Q99571(Tchem)
UniProt: Q99571
LinkDB
Position
12q24.31
AA seq 388 aa
MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
VSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIP
DATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLK
AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYC
MKKRLYYREKKYKYVEDYEQGLASELDQ
NT seq 1167 nt   +upstreamnt  +downstreamnt
atggcgggctgctgcgccgcgctggcggccttcctgttcgagtacgacacgccgcgcatc
gtgctcatccgcagccgcaaagtggggctcatgaaccgcgccgtgcaactgctcatcctg
gcctacgtcatcgggtgggtgtttgtgtgggaaaagggctaccaggaaactgactccgtg
gtcagctccgttacgaccaaggtcaagggcgtggctgtgaccaacacttctaaacttgga
ttccggatctgggatgtggcggattatgtgataccagctcaggaggaaaactccctcttc
gtcatgaccaacgtgatcctcaccatgaaccagacacagggcctgtgccccgagattcca
gatgcgaccactgtgtgtaaatcagatgccagctgtactgccggctctgccggcacccac
agcaacggagtctcaacaggcaggtgcgtagctttcaacgggtctgtcaagacgtgtgag
gtggcggcctggtgcccggtggaggatgacacacacgtgccacaacctgcttttttaaag
gctgcagaaaacttcactcttttggttaagaacaacatctggtatcccaaatttaatttc
agcaagaggaatatccttcccaacatcaccactacttacctcaagtcgtgcatttatgat
gctaaaacagatcccttctgccccatattccgtcttggcaaaatagtggagaacgcagga
cacagtttccaggacatggccgtggagggaggcatcatgggcatccaggtcaactgggac
tgcaacctggacagagccgcctccctctgcttgcccaggtactccttccgccgcctcgat
acacgggacgttgagcacaacgtatctcctggctacaatttcaggtttgccaagtactac
agagacctggctggcaacgagcagcgcacgctcatcaaggcctatggcatccgcttcgac
atcattgtgtttgggaaggcagggaaatttgacatcatccccactatgatcaacatcggc
tctggcctggcactgctaggcatggcgaccgtgctgtgtgacatcatagtcctctactgc
atgaagaaaagactctactatcgggagaagaaatataaatatgtggaagattacgagcag
ggtcttgctagtgagctggaccagtga

KEGG   Homo sapiens (human): 5026
Entry
5026              CDS       T01001                                 

Gene name
P2RX5, LRH-1, P2X5, P2X5R
Definition
(RefSeq) purinergic receptor P2X 5
  KO
K05219  P2X purinoceptor 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    5026 (P2RX5)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5026 (P2RX5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    5026 (P2RX5)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   5026 (P2RX5)
SSDB
Motif
Pfam: P2X_receptor
Other DBs
NCBI-GeneID: 5026
NCBI-ProteinID: NP_002552
OMIM: 602836
HGNC: 8536
Ensembl: ENSG00000083454
Vega: OTTHUMG00000090700
Pharos: Q93086(Tbio)
UniProt: Q93086
LinkDB
Position
17p13.2
AA seq 422 aa
MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE
NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
ST
NT seq 1269 nt   +upstreamnt  +downstreamnt
atggggcaggcgggctgcaaggggctctgcctgtcgctgttcgactacaagaccgagaag
tatgtcatcgccaagaacaagaaggtgggcctgctgtaccggctgctgcaggcctccatc
ctggcgtacctggtcgtatgggtgttcctgataaagaagggttaccaagacgtcgacacc
tccctgcagagtgctgtcatcaccaaagtcaagggcgtggccttcaccaacacctcggat
cttgggcagcggatctgggatgtcgccgactacgtcattccagcccagggagagaacgtc
ttttttgtggtcaccaacctgattgtgacccccaaccagcggcagaacgtctgtgctgag
aatgaaggcattcctgatggcgcgtgctccaaggacagcgactgccacgctggggaagcg
gttacagctggaaacggagtgaagaccggccgctgcctgcggagagagaacttggccagg
ggcacctgtgagatctttgcctggtgcccgttggagacaagctccaggccggaggagcca
ttcctgaaggaggccgaagacttcaccattttcataaagaaccacatccgtttccccaaa
ttcaacttctccaaaagcaatgtgatggacgtcaaggacagatctttcctgaaatcatgc
cactttggccccaagaaccactactgccccatcttccgactgggctccgtgatccgctgg
gccgggagcgacttccaggatatagccctggagggtggcgtgataggaattaatattgaa
tggaactgtgatcttgataaagctgcctctgagtgccaccctcactattcttttagccgt
ctggacaataaactttcaaagtctgtctcctccgggtacaacttcagatttgccagatat
taccgagacgcagccggggtggagttccgcaccctgatgaaagcctacgggatccgcttt
gacgtgatggtgaacggcaagggtgctttcttctgcgacctggtactcatctacctcatc
aaaaagagagagttttaccgtgacaagaagtacgaggaagtgaggggcctagaagacagt
tcccaggaggccgaggacgaggcatcggggctggggctatctgagcagctcacatctggg
ccagggctgctggggatgccggagcagcaggagctgcaggagccacccgaggcgaagcgt
ggaagcagcagtcagaaggggaacggatctgtgtgcccacagctcctggagccccacagg
agcacgtga

KEGG   Homo sapiens (human): 5027
Entry
5027              CDS       T01001                                 

Gene name
P2RX7, P2X7
Definition
(RefSeq) purinergic receptor P2X 7
  KO
K05220  P2X purinoceptor 7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04621  NOD-like receptor signaling pathway
Drug target
Brilliant blue G: D10799<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    5027 (P2RX7)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5027 (P2RX7)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    5027 (P2RX7)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    5027 (P2RX7)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   5027 (P2RX7)
SSDB
Motif
Pfam: P2X_receptor Keratin_matx Ribosomal_L5_C
Other DBs
NCBI-GeneID: 5027
NCBI-ProteinID: NP_002553
OMIM: 602566
HGNC: 8537
Ensembl: ENSG00000089041
Vega: OTTHUMG00000169153
Pharos: Q99572(Tchem)
UniProt: Q99572
LinkDB
Position
12q24.31
AA seq 595 aa
MPACCSCSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVCFALVSDKLYQRKEPVISS
VHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCP
EYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEAPRPA
LLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIFRETGD
NFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYK
ENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTYSS
NCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRS
LQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCG
SCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDS
TNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
NT seq 1788 nt   +upstreamnt  +downstreamnt
atgccggcctgctgcagctgcagtgatgttttccagtatgagacgaacaaagtcactcgg
atccagagcatgaattatggcaccattaagtggttcttccacgtgatcatcttttcctac
gtttgctttgctctggtgagtgacaagctgtaccagcggaaagagcctgtcatcagttct
gtgcacaccaaggtgaaggggatagcagaggtgaaagaggagatcgtggagaatggagtg
aagaagttggtgcacagtgtctttgacaccgcagactacaccttccctttgcaggggaac
tctttcttcgtgatgacaaactttctcaaaacagaaggccaagagcagcggttgtgtccc
gagtatcccacccgcaggacgctctgttcctctgaccgaggttgtaaaaagggatggatg
gacccgcagagcaaaggaattcagaccggaaggtgtgtagtgtatgaagggaaccagaag
acctgtgaagtctctgcctggtgccccatcgaggcagtggaagaggccccccggcctgct
ctcttgaacagtgccgaaaacttcactgtgctcatcaagaacaatatcgacttccccggc
cacaactacaccacgagaaacatcctgccaggtttaaacatcacttgtaccttccacaag
actcagaatccacagtgtcccattttccgactaggagacatcttccgagaaacaggcgat
aatttttcagatgtggcaattcagggcggaataatgggcattgagatctactgggactgc
aacctagaccgttggttccatcactgccgtcccaaatacagtttccgtcgccttgacgac
aagaccaccaacgtgtccttgtaccctggctacaacttcagatacgccaagtactacaag
gaaaacaatgttgagaaacggactctgataaaagtcttcgggatccgttttgacatcctg
gtttttggcaccggaggaaaatttgacattatccagctggttgtgtacatcggctcaacc
ctctcctacttcggtctggccgctgtgttcatcgacttcctcatcgacacttactccagt
aactgctgtcgctcccatatttatccctggtgcaagtgctgtcagccctgtgtggtcaac
gaatactactacaggaagaagtgcgagtccattgtggagccaaagccgacattaaagtat
gtgtcctttgtggatgaatcccacattaggatggtgaaccagcagctactagggagaagt
ctgcaagatgtcaagggccaagaagtcccaagacctgcgatggacttcacagatttgtcc
aggctgcccctggccctccatgacacacccccgattcctggacaaccagaggagatacag
ctgcttagaaaggaggcgactcctagatccagggatagccccgtctggtgccagtgtgga
agctgcctcccatctcaactccctgagagccacaggtgcctggaggagctgtgctgccgg
aaaaagccgggggcctgcatcaccacctcagagctgttcaggaagctggtcctgtccaga
cacgtcctgcagttcctcctgctctaccaggagcccttgctggcgctggatgtggattcc
accaacagccggctgcggcactgtgcctacaggtgctacgccacctggcgcttcggctcc
caggacatggctgactttgccatcctgcccagctgctgccgctggaggatccggaaagag
tttccgaagagtgaagggcagtacagtggcttcaagagtccttactga

KEGG   Homo sapiens (human): 9127
Entry
9127              CDS       T01001                                 

Gene name
P2RX6, P2RXL1, P2X6, P2XM
Definition
(RefSeq) purinergic receptor P2X 6
  KO
K05221  P2X purinoceptor 6
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    9127 (P2RX6)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    9127 (P2RX6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    9127 (P2RX6)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   9127 (P2RX6)
SSDB
Motif
Pfam: P2X_receptor
Other DBs
NCBI-GeneID: 9127
NCBI-ProteinID: NP_005437
OMIM: 608077
HGNC: 8538
Ensembl: ENSG00000099957
Vega: OTTHUMG00000150689
Pharos: O15547(Tbio)
UniProt: O15547
LinkDB
Position
22q11.21
AA seq 441 aa
MCPQLAGAGSMGSPGATTGWGLLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLA
KKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTP
AQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHRTCEIWSWCPVE
SGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPV
FRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQEKSYNFRTAT
HWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVVTFFCDLLLL
YVDREAHFYWRTKYEEAKAPKATANSVWRELALASQARLAECLRRSSAPAPTATAAGSQT
QTPGWPCPSSDTHLPTHSGSL
NT seq 1326 nt   +upstreamnt  +downstreamnt
atgtgcccgcagctagcaggagctggcagcatgggctccccaggggctacgacaggctgg
gggcttctggattataagacggagaagtatgtgatgaccaggaactggcgggtgggcgcc
ctgcagaggctgctgcagtttgggatcgtggtctatgtggtagggtgggctctcctcgcc
aaaaaaggctaccaggagcgggacctggaaccccagttttccatcatcaccaaactcaaa
ggggtttccgtcactcagatcaaggagcttggaaaccggctgtgggatgtggccgacttc
gtgaagccacctcagggagagaacgtgttcttcttggtgaccaacttccttgtgacgcca
gcccaagttcagggcagatgcccagagcacccgtccgtcccactggctaactgctgggtc
gacgaggactgccccgaaggggagggaggcacacacagccacggtgtaaaaacaggccag
tgtgtggtgttcaatgggacccacaggacctgtgagatctggagttggtgccccgtggag
agtggcgttgtgccctcgaggcccctgctggcccaggcccagaacttcacactgttcatc
aaaaacacagtcaccttcagcaagttcaacttctctaagtccaatgccttggagacctgg
gaccccacctattttaagcactgccgctatgaaccacaattcagcccctactgtcccgtg
ttccgcattggggacctcgtggccaaggctggagggaccttcgaggacctggcgttgctg
ggtggctctgtaggcatcagagttcactgggattgtgacctggacaccggggactctggc
tgctggcctcactactccttccagctgcaggagaagagctacaacttcaggacagccact
cactggtgggagcaaccgggtgtggaggcccgcaccctgctcaagctctatggaatccgc
ttcgacatcctcgtcaccgggcaggcagggaagttcgggctcatccccacggccgtcaca
ctgggcaccggggcagcttggctgggcgtggtcacctttttctgtgacctgctactgctg
tatgtggatagagaagcccatttctactggaggacaaagtatgaggaggccaaggccccg
aaagcaaccgccaactctgtgtggagggagctggcccttgcatcccaagcccgactggcc
gagtgcctcagacggagctcagcacctgcacccacggccactgctgctgggagtcagaca
cagacaccaggatggccctgtccaagttctgacacccacttgccaacccattccgggagc
ctgtag

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