Homo sapiens (human): 23035
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Entry
23035 CDS
T01001
Symbol
PHLPP2, PHLPPL, PPM3B
Name
(RefSeq) PH domain and leucine rich repeat protein phosphatase 2
KO
K16340
PH domain and leucine-rich repeat-containing protein phosphatase [EC:
3.1.3.16
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04151
PI3K-Akt signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
23035 (PHLPP2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
23035 (PHLPP2)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
23035 (PHLPP2)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein serine/threonine phosphatases
Mg2+- or Mn2+- dependent protein phosphatases (PPMs)
PPM1 phosphatases (PP2C)
23035 (PHLPP2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
LRR_8
LRR_4
PP2C
LRR_1
LRR_6
PH
Motif
Other DBs
NCBI-GeneID:
23035
NCBI-ProteinID:
NP_055835
OMIM:
611066
HGNC:
29149
Ensembl:
ENSG00000040199
UniProt:
Q6ZVD8
LinkDB
All DBs
Position
16:complement(71644924..71724701)
Genome browser
AA seq
1323 aa
AA seq
DB search
MKRNGSRNCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTTTSSSSSSSSSSS
DLHLVLCTVETPASEICAGEGRESLYLQLHGDLVRRLEPTERPLQIVYDYLSRLGFDDPV
RIQEEATNPDLGCMIRFYGEKPCHMDRLDRILLSGIYNVRKGKTQLHKWAERLVVLCGTC
LIVSSVKDCQTGKMHILPLVGGKIEEVKRRQYSLAFSSAGAQAQTYHVSFETLAEYQRWQ
RQASKVVSQRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQ
LKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTL
PEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHV
DLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQLHCGRNQLRELTLSGF
SLRTLYASSNRLTAVNVYPVPSLLTFLDLSRNLLECVPDWACEAKKIEVLDVSYNLLTEV
PVRILSSLSLRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLN
ASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLHLRILHLANNQLQTFP
ASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPEILQLPQIQFVDL
SCNDLTEILIPEALPATLQDLDLTGNTNLVLEHKTLDIFSHITTLKIDQKPLPTTDSTVT
STFWSHGLAEMAGQRNKLCVSALAMDSFAEGVGAVYGMFDGDRNEELPRLLQCTMADVLL
EEVQQSTNDTVFMANTFLVSHRKLGMAGQKLGSSALLCYIRPDTADPASSFSLTVANVGT
CQAVLCRGGKPVPLSKVFSLEQDPEEAQRVKDQKAIITEDNKVNGVTCCTRMLGCTYLYP
WILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQDPLAAAKKLCTLAQSY
GCQDNVGAMVVYLNIGEEGCTCEMNGLTLPGPVGFASTTTIKDAPKPATPSSSSGIASEF
SSEMSTSEVSSEVGSTASDEHNAGGLDTALLPRPERRCSLHPTPTSGLFQRQPSSATFSS
NQSDNGLDSDDDQPVEGVITNGSKVEVEVDIHCCRGRDLENSPPLIESSPTLCSEEHARG
SCFGIRRQNSVNSGMLLPMSKDRMELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATE
VPKRKTGYFAAPTQMEPEDQFVVPHDLEEEVKEQMKQHQDSRLEPEPHEEDRTEPPEEFD
TAL
NT seq
3972 nt
NT seq
+upstream
nt +downstream
nt
atgaaacgcaatgggagcagaaattgtttgaataggagaagtaggtttggttctcgagaa
agagactggctaagagaagatgtaaagagaggctgtgtttacctttatggagcagacact
accactgccactacaaccaccaccacctcctcttcctcttcctcctcctcctcttcctct
gacttacatctcgtcctttgcactgtagagacaccagcatcagaaatatgtgctggagag
ggaagagaaagtctttatttacagcttcatggagacctggtcaggagactggaacctact
gaacgacctcttcagatcgtttatgattacttatccaggctgggatttgatgatcctgtg
cgcatacaggaggaggctacaaatcctgacctcggctgtatgattcgattttatggtgaa
aaaccatgccacatggatcgtttggatcgaatcctattgtctggcatctataatgtacgc
aagggaaagacccagctgcataagtgggctgagcgcctagttgtcctctgtggtacctgc
cttatcgtttcctcagtgaaggattgtcaaactggaaagatgcacattttgcctctggtt
ggtggaaagatagaagaagtgaagcgacggcaatactcccttgctttcagctcagcagga
gcccaagctcagacctatcatgtcagcttcgagactttggccgagtaccagcgatggcaa
cggcaagcatccaaggtggtgtcccagcgaatcagtaccgtggatctctcgtgttacagc
ctcgaggaggttcctgagcatctcttctatagtcaagatattacctacctcaacttgcga
cacaacttcatgcagttagaaagacccggaggcctcgatacactctacaaattttctcaa
ctgaagggcctgaacttgtcccataataaacttgggttgtttcctatattgttatgcgag
atctctaccctgactgagctcaacctttcctgtaatggatttcatgacctaccaagtcaa
attggcaatctgctaaatcttcaaaccctctgtcttgatggcaactttctgactacttta
cctgaagaattgggaaatctacaacagctttcctccttgggaatttccttcaacaacttt
agtcaaattcctgaggtttatgagaaactcactatgttagatagagtggttatggcagga
aattgcctggaagtcctgaacttaggggtgctgaataggatgaaccatatcaagcatgtg
gatttaaggatgaaccatttgaaaaccatggttattgaaaatctggagggaaataaacac
atcacccacgtggatctgcgggacaaccgactgactgacttggatcttagctccttatgc
agcttggaacagctgcactgtgggcggaatcagctgagggagctaacactcagtggcttt
tcccttcggaccctctatgccagttccaacaggctgacagcagtgaacgtctatccagta
cccagcctgctcactttcttggatctctcccgaaacctgctagagtgtgtccctgactgg
gcctgtgaagcaaagaagatagaagtattagatgtgagctataatcttctcacagaggtt
cccgtgagaattctgagtagcttgagtcttagaaaactgatgctgggacacaatcatgtg
caaaaccttccaacactggtagagcacatccccctcgaggtgctggatcttcagcataat
gcactcacgaggctgccagacaccctcttctccaaggccttaaatctcagatacttgaat
gcatctgcaaatagtctggagtctttaccatccgcctgcactggagaggagagtttgagt
atgctgcagctgctttatctgaccaacaatctcctgacggatcagtgcatacctgtcctg
gtagggcacctgcacctgcgaatcttgcaccttgcaaacaatcagttacagacctttcct
gcaagcaaactaaataaattggagcaattggaggaactgaacctaagtggcaacaagctt
aaaaccattcccacaaccatagcaaactgtaaaaggctgcacacccttgttgcacactcc
aacaacatcagcattttcccagaaatactgcagttgcctcagatccagtttgtagaccta
agttgcaacgacttgacagaaatcctgattccagaggctttgcctgctacattacaagac
cttgacctgactggaaatacaaatctggttctggaacacaagacactggacatatttagc
catatcacaaccctgaaaattgatcagaaacctttgccaaccacagattctacagttacg
tcaaccttctggagccatggactggctgagatggcagggcagagaaataagctgtgtgtc
tcagcacttgctatggatagctttgcagagggggtgggagctgtgtatggcatgtttgat
ggagaccgaaatgaggagctcccgcgcctgctgcagtgtacgatggcagatgtgctttta
gaagaggtacagcagtcaactaatgacacagttttcatggctaacaccttcttggtatct
cacaggaaattaggaatggctggccagaagttgggctcctccgctctcctgtgctacatc
cgccctgacactgccgatccagcaagtagctttagcttgactgtagccaatgttggcacg
tgccaagcagtcctgtgccgaggtgggaagccagtgcccctctctaaagtcttcagcctg
gagcaggacccagaggaggctcaaagggtgaaggaccaaaaagccatcatcacagaggac
aacaaagtgaatggggtaacctgctgtacccggatgctgggctgtacatacctctaccct
tggatcctccccaagccccacatatcttccactccgctgaccattcaagatgagttgctg
attctgggaaacaaagcattgtgggaacacttgtcctacacagaagctgtcaatgctgta
cgtcacgtacaagacccattagcagctgctaagaagctgtgcacattagcgcagagctat
ggctgtcaggacaatgtaggggcgatggtagtttatttgaatattggtgaggaaggctgc
acttgtgaaatgaatgggctcaccctcccaggtcctgtgggatttgcttcaaccaccact
atcaaggatgcccctaagccagccactccatcctctagcagtgggattgcctctgagttc
agcagtgagatgtccacctcagaggtgagcagtgaagtggggtccactgcttctgatgag
cataatgctgggggcctggacactgccttgcttccgaggccagagcggcgctgcagcctc
cacccaacacccacctctgggctgtttcagcgccagccttcttctgctaccttctccagt
aaccagtctgacaacggcctggacagtgatgatgaccagcccgttgagggggtcataacc
aatggcagcaaggtagaggtggaagtagacatccactgctgcagggggagggatctggag
aactcaccccctctcatagagagttctcctaccctgtgttctgaggaacatgctagaggg
tcgtgttttgggatccgaagacagaacagtgtgaatagtggcatgctcctgccaatgagc
aaggacaggatggagttacagaagtctccctccacctcctgcctctatgggaagaaactc
tccaatggctctattgtgcccctagaggacagcctgaacctcattgaagtggccacagaa
gtgcccaagaggaaaactggctattttgctgcccccactcagatggaaccagaggaccag
tttgttgtgcctcatgacctggaagaagaagtgaaggaacaaatgaaacagcaccaggac
agccggctcgagcctgagccccatgaagaggatcggaccgagcccccggaggagttcgac
acagcactatga
DBGET
integrated database retrieval system
