KEGG   Homo sapiens (human): 2327
Entry
2327              CDS       T01001                                 

Gene name
FMO2, FMO1B1
Definition
(RefSeq) flavin containing dimethylaniline monoxygenase 2
  KO
K00485  dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00982  Drug metabolism - cytochrome P450
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00982 Drug metabolism - cytochrome P450
    2327 (FMO2)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.8  flavin-containing monooxygenase
     2327 (FMO2)
SSDB
Motif
Pfam: FMO-like Pyr_redox_3 Pyr_redox_2 K_oxygenase NAD_binding_8 DAO Pyr_redox IlvN Shikimate_DH 2-Hacid_dh_C DUF3146 ApbA
Other DBs
NCBI-GeneID: 2327
NCBI-ProteinID: NP_001451
OMIM: 603955
HGNC: 3770
Ensembl: ENSG00000094963
Vega: OTTHUMG00000035504
Pharos: Q99518(Tbio)
UniProt: Q99518 Q5JPC7
LinkDB
Position
1q24.3
AA seq 535 aa
MAKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVT
NTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDFS
SSGQWKVVTQSNGKEQSAVFDAVMVCSGHHILPHIPLKSFPGMERFKGQYFHSRQYKHPD
GFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFR
SMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLCGAIKVK
STVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPFLEDSLVKVENNMVSLYKYIFPAH
LDKSTLACIGLIQPLGSIFPTAELQARWVTRVFKGLCSLPSERTMMMDIIKRNEKRIDLF
GESQSQTLQTNYVDYLDELALEIGAKPDFCSLLFKDPKLAVRLYFGPCNSYQYRLVGPGQ
WEGARNAIFTQKQRILKPLKTRALKDSSNFSVSFLLKILGLLAVVVAFFCQLQWS
NT seq 1608 nt   +upstreamnt  +downstreamnt
atggcaaagaaggtagctgtgattggagctggggtcagtggcctaatttctctgaagtgc
tgtgtggatgagggacttgagcccacttgctttgagagaactgaagatattggaggagtg
tggaggttcaaagagaatgtggaagatggccgagcaagtatctatcaatctgtcgttacc
aacaccagcaaagaaatgtcctgtttcagtgactttccaatgcctgaagattttccaaac
ttcctgcataattctaaacttctggaatatttcaggatttttgctaaaaaatttgatctg
ctaaaatatattcagttccagacaactgtccttagtgtgagaaaatgtccagatttctca
tcctctggccaatggaaggttgtcactcagagcaacggcaaggagcagagtgctgtcttt
gacgcagttatggtttgcagtggccaccacattctacctcatatcccactgaagtcattt
ccaggtatggagaggttcaaaggccaatatttccatagccgccaatacaagcatccagat
ggatttgagggaaaacgcatcctggtgattggaatgggaaactcaggctcagatattgct
gttgagctgagtaagaatgctgctcaggtttttatcagcaccaggcatggcacctgggtc
atgagccgtatctctgaagatggctatccttgggactcagtgttccacacccggtttcgt
tctatgctccgcaatgtactgccacgaacagctgtaaaatggatgatagaacaacagatg
aatcggtggttcaaccatgaaaattatggccttgagcctcaaaacaaatacattatgaag
gaacctgtactaaatgatgatgtcccaagtcgtctactctgtggagccatcaaggtgaaa
tctacagtgaaagagctcacagaaacttctgccatctttgaggatggaacagtggaggag
aacattgatgtcatcatttttgcaacaggatatagtttctcttttcccttccttgaagat
tcactcgttaaagtagagaataatatggtctcactgtataaatacatattccccgctcac
ctggacaagtcaaccctcgcgtgcattggtctcatccagcccctaggttccattttccca
actgctgaacttcaagctcgttgggtgacaagagttttcaaaggcttgtgtagcctgccc
tcagagagaactatgatgatggacattatcaaaaggaatgaaaaaagaattgacctgttt
ggagaaagccagagccagacgttgcagaccaattatgttgactacttggacgagctcgcc
ttagagataggtgcgaagccagatttctgctctctcttgttcaaagatcctaaactggct
gtgagactctatttcggaccctgcaactcctatcagtatcgcctggttgggcctgggcaa
tgggaaggagccagaaatgccatcttcacccagaaacaaagaatactgaagccactcaag
actcgggccctgaaggattcatctaatttctcagtttcttttctgttgaaaatcctgggc
cttcttgctgttgttgtggcctttttttgccaacttcaatggtcctag

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