Homo sapiens (human): 29126
Entry
29126 CDS
T01001
Gene name
CD274, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1
Definition
(RefSeq) CD274 molecule
KO
K06745
programmed cell death 1 ligand 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04514
Cell adhesion molecules (CAMs)
hsa05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Drug target
Atezolizumab:
D10773
Avelumab:
D10817
Durvalumab:
D10808
Inbakicept:
D11747
Lodapolimab:
D11532
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04514 Cell adhesion molecules (CAMs)
29126 (CD274)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
29126 (CD274)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hsa04090
]
29126 (CD274)
CD molecules [BR:
hsa04090
]
Proteins
29126 (CD274)
SSDB
Motif
Pfam:
Ig_3
I-set
C2-set_2
ig
V-set
Ig_2
C1-set
Ig_6
V-set_CD47
Herpes_gE
Izumo-Ig
Other DBs
NCBI-GeneID:
29126
NCBI-ProteinID:
NP_054862
OMIM:
605402
HGNC:
17635
Ensembl:
ENSG00000120217
Vega:
OTTHUMG00000019503
Pharos:
Q9NZQ7
(Tclin)
UniProt:
Q9NZQ7
LinkDB
Structure
PDB:
5O45
6NP9
5N2F
5JDS
5C3T
6NNV
4Z18
5NIU
6R3K
5J89
3SBW
5O4Y
5XJ4
5J8O
6NOJ
5N2D
6NM7
4ZQK
3BIS
3BIK
5X8M
6RPG
6NOS
5JDR
3FN3
6NM8
5GGT
5IUS
5XXY
5X8L
5GRJ
Position
9p24.1
AA seq
290 aa
MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEME
DKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGG
ADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTT
TTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTH
LVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET
NT seq
873 nt
+upstream
nt +downstream
nt
atgaggatatttgctgtctttatattcatgacctactggcatttgctgaacgcatttact
gtcacggttcccaaggacctatatgtggtagagtatggtagcaatatgacaattgaatgc
aaattcccagtagaaaaacaattagacctggctgcactaattgtctattgggaaatggag
gataagaacattattcaatttgtgcatggagaggaagacctgaaggttcagcatagtagc
tacagacagagggcccggctgttgaaggaccagctctccctgggaaatgctgcacttcag
atcacagatgtgaaattgcaggatgcaggggtgtaccgctgcatgatcagctatggtggt
gccgactacaagcgaattactgtgaaagtcaatgccccatacaacaaaatcaaccaaaga
attttggttgtggatccagtcacctctgaacatgaactgacatgtcaggctgagggctac
cccaaggccgaagtcatctggacaagcagtgaccatcaagtcctgagtggtaagaccacc
accaccaattccaagagagaggagaagcttttcaatgtgaccagcacactgagaatcaac
acaacaactaatgagattttctactgcacttttaggagattagatcctgaggaaaaccat
acagctgaattggtcatcccagaactacctctggcacatcctccaaatgaaaggactcac
ttggtaattctgggagccatcttattatgccttggtgtagcactgacattcatcttccgt
ttaagaaaagggagaatgatggatgtgaaaaaatgtggcatccaagatacaaactcaaag
aagcaaagtgatacacatttggaggagacgtaa
DBGET
integrated database retrieval system
