Homo sapiens (human): 3055
Entry
3055 CDS
T01001
Gene name
HCK, JTK9, p59Hck, p61Hck
Definition
(RefSeq) HCK proto-oncogene, Src family tyrosine kinase
KO
K08893
hemopoietic cell kinase [EC:
2.7.10.2
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04062
Chemokine signaling pathway
hsa04666
Fc gamma R-mediated phagocytosis
hsa05130
Pathogenic Escherichia coli infection
hsa05167
Kaposi sarcoma-associated herpesvirus infection
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
3055 (HCK)
04062 Chemokine signaling pathway
3055 (HCK)
09160 Human Diseases
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
3055 (HCK)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
3055 (HCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
3055 (HCK)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
3055 (HCK)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
3055 (HCK)
Protein kinases [BR:
hsa01001
]
Non-receptor tyrosine kinases
SRC family
3055 (HCK)
Membrane trafficking [BR:
hsa04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
3055 (HCK)
SSDB
Motif
Pfam:
Pkinase_Tyr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
Haspin_kinase
Other DBs
NCBI-GeneID:
3055
NCBI-ProteinID:
NP_002101
OMIM:
142370
HGNC:
4840
Ensembl:
ENSG00000101336
Vega:
OTTHUMG00000032204
Pharos:
P08631
(Tclin)
UniProt:
P08631
LinkDB
Structure
PDB:
5H0B
5ZJ6
5H0H
5H0G
4U5W
5H09
2HK5
1QCF
5H0E
2C0T
3VS3
3VRZ
2C0I
3VS6
3VS1
3VRY
1BU1
1AD5
3VS2
3NHN
3VS4
5NUH
4LUD
3VS5
2C0O
3VS0
3VS7
2HCK
4LUE
2OJ2
2OI3
4HCK
5HCK
3HCK
Position
20q11.21
AA seq
526 aa
MGGRSSCEDPGCPRDEERAPRMGCMKSKFLQVGGNTFSKTETSASPHCPVYVPDPTSTIK
PGPNSHNSNTPGIREAGSEDIIVVALYDYEAIHHEDLSFQKGDQMVVLEESGEWWKARSL
ATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSY
SLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVP
CMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE
AFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLID
FSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFP
IKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPE
NCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQYQQQP
NT seq
1581 nt
+upstream
nt +downstream
nt
ctgggggggcgctcaagctgcgaggatccgggctgcccgcgagacgaggagcgggcgccc
aggatggggtgcatgaagtccaagttcctccaggtcggaggcaatacattctcaaaaact
gaaaccagcgccagcccacactgtcctgtgtacgtgccggatcccacatccaccatcaag
ccggggcctaatagccacaacagcaacacaccaggaatcagggaggcaggctctgaggac
atcatcgtggttgccctgtatgattacgaggccattcaccacgaagacctcagcttccag
aagggggaccagatggtggtcctagaggaatccggggagtggtggaaggctcgatccctg
gccacccggaaggagggctacatcccaagcaactatgtcgcccgcgttgactctctggag
acagaggagtggtttttcaagggcatcagccggaaggacgcagagcgccaactgctggct
cccggcaacatgctgggctccttcatgatccgggatagcgagaccactaaaggaagctac
tctttgtccgtgcgagactacgaccctcggcagggagataccgtgaaacattacaagatc
cggaccctggacaacgggggcttctacatatccccccgaagcaccttcagcactctgcag
gagctggtggaccactacaagaaggggaacgacgggctctgccagaaactgtcggtgccc
tgcatgtcttccaagccccagaagccttgggagaaagatgcctgggagatccctcgggaa
tccctcaagctggagaagaaacttggagctgggcagtttggggaagtctggatggccacc
tacaacaagcacaccaaggtggcagtgaagacgatgaagccagggagcatgtcggtggag
gccttcctggcagaggccaacgtgatgaaaactctgcagcatgacaagctggtcaaactt
catgcggtggtcaccaaggagcccatctacatcatcacggagttcatggccaaaggaagc
ttgctggactttctgaaaagtgatgagggcagcaagcagccattgccaaaactcattgac
ttctcagcccagattgcagaaggcatggccttcatcgagcagaggaactacatccaccga
gacctccgagctgccaacatcttggtctctgcatccctggtgtgtaagattgctgacttt
ggcctggcccgggtcattgaggacaacgagtacacggctcgggaaggggccaagttcccc
atcaagtggacagctcctgaagccatcaactttggctccttcaccatcaagtcagacgtc
tggtcctttggtatcctgctgatggagatcgtcacctacggccggatcccttacccaggg
atgtcaaaccctgaagtgatccgagctctggagcgtggataccggatgcctcgcccagag
aactgcccagaggagctctacaacatcatgatgcgctgctggaaaaaccgtccggaggag
cggccgaccttcgaatacatccagagtgtgctggatgacttctacacggccacagagagc
cagtaccaacagcagccatga
DBGET
integrated database retrieval system
