Homo sapiens (human): 3360
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Entry
3360 CDS
T01001
Symbol
HTR4, 5-HT4, 5-HT4R
Name
(RefSeq) 5-hydroxytryptamine receptor 4
KO
K04160
5-hydroxytryptamine receptor 4
Organism
hsa
Homo sapiens (human)
Pathway
hsa04024
cAMP signaling pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04726
Serotonergic synapse
Drug target
Cinitapride (
DG01520
):
D07700
D07701
Cisapride (
DG00056
):
D00274
D02092
Fabesetron hydrochloride:
D01838
Felcisetrag:
D12157
Mosapride (
DG01285
):
D01994
<JP>
D08236
Naronapride (
DG01335
):
D09933
D09934
Piboserod hydrochloride:
D05471
Prucalopride (
DG00080
):
D09205
D10152
<US>
Relenopride (
DG02948
):
D11220
D11221
Renzapride:
D06396
Sulamserod hydrochloride:
D05941
Tegaserod (
DG00081
):
D02730
D06056
Velusetrag (
DG01336
):
D09693
D09694
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
3360 (HTR4)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
3360 (HTR4)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
3360 (HTR4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
3360 (HTR4)
G protein-coupled receptors [BR:
hsa04030
]
Rhodopsin family
Biogenic amine
Serotonin
3360 (HTR4)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_1
DUF6249
zf-LITAF-like
Motif
Other DBs
NCBI-GeneID:
3360
NCBI-ProteinID:
NP_000861
OMIM:
602164
HGNC:
5299
Ensembl:
ENSG00000164270
Pharos:
Q13639
(Tclin)
UniProt:
Q13639
A0A2D3FAF9
Structure
PDB
PDBj
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All DBs
Position
5:complement(148451032..148654527)
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AA seq
388 aa
AA seq
DB search
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
AVECGGQWESQCHPPATSPLVAAQPSDT
NT seq
1167 nt
NT seq
+upstream
nt +downstream
nt
atggacaaacttgatgctaatgtgagttctgaggagggtttcgggtcagtggagaaggtg
gtgctgctcacgtttctctcgacggttatcctgatggccatcttggggaacctgctggtg
atggtggctgtgtgctgggacaggcagctcaggaaaataaaaacaaattatttcattgta
tctcttgcttttgcggatctgctggtttcggtgctggtgatgccctttggtgccattgag
ctggttcaagacatctggatttatggggaggtgttttgtcttgttcggacatctctggac
gtcctgctcacaacggcatcgatttttcacctgtgctgcatttctctggataggtattac
gccatctgctgccagcctttggtctataggaacaagatgacccctctgcgcatcgcatta
atgctgggaggctgctgggtcatccccacgtttatttcttttctccctataatgcaaggc
tggaataacattggcataattgatttgatagaaaagaggaagttcaaccagaactctaac
tctacgtactgtgtcttcatggtcaacaagccctacgccatcacctgctctgtggtggcc
ttctacatcccatttctcctcatggtgctggcctattaccgcatctatgtcacagctaag
gagcatgcccatcagatccagatgttacaacgggcaggagcctcctccgagagcaggcct
cagtcggcagaccagcatagcactcatcgcatgaggacagagaccaaagcagccaagacc
ctgtgcatcatcatgggttgcttctgcctctgctgggcaccattctttgtcaccaatatt
gtggatcctttcatagactacactgtccctgggcaggtgtggactgctttcctctggctc
ggctatatcaattccgggttgaacccttttctctacgccttcttgaataagtcttttaga
cgtgccttcctcatcatcctctgctgtgatgatgagcgctaccgaagaccttccattctg
ggccagactgtcccttgttcaaccacaaccattaatggatccacacatgtactaagggat
gcagtggagtgtggtggccagtgggagagtcagtgtcacccgccagcaacttctcctttg
gtggctgctcagcccagtgacacttag
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