KEGG   Homo sapiens (human): 3516Help
Entry
3516              CDS       T01001                                 

Gene name
RBPJ, AOS3, CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl
Definition
(RefSeq) recombination signal binding protein for immunoglobulin kappa J region
  KO
K06053  recombining binding protein suppressor of hairless
Organism
hsa  Homo sapiens (human)
Pathway
hsa04330  Notch signaling pathway
hsa04658  Th1 and Th2 cell differentiation
hsa05017  Spinocerebellar ataxia
hsa05165  Human papillomavirus infection
hsa05169  Epstein-Barr virus infection
hsa05203  Viral carcinogenesis
Network
nt06116  NOTCH signaling (viruses)
nt06165  Epstein-Barr virus (EBV)
nt06166  Human papillomavirus (HPV)
  Element
N00224  EBV EBNALP RBP-Jk-mediated transcription
N00225  EBV EBNA2 to RBP-Jk-mediated transcription
N00226  EBV EBNA3A/3B/3C to RBP-Jk-mediated transcription
N00380  HPV E6 to Notch signaling pathway
N00381  HPV E6 to Notch signaling pathway
N00382  HPV E6 to Notch signaling pathway
Disease
H01413  Adams-Oliver syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    3516 (RBPJ)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    3516 (RBPJ)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    3516 (RBPJ)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    3516 (RBPJ)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    3516 (RBPJ)
   05165 Human papillomavirus infection
    3516 (RBPJ)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    3516 (RBPJ)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Other transcription factors
   Others
    3516 (RBPJ)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: BTD LAG1-DNAbind TIG RHD_dimer
Motif
Other DBs
NCBI-GeneID: 3516
NCBI-ProteinID: NP_005340
OMIM: 147183
HGNC: 5724
Ensembl: ENSG00000168214
Vega: OTTHUMG00000097793
Pharos: Q06330(Tbio)
UniProt: Q06330
LinkDB All DBs
Structure
PDB: 

Position
4p15.2
AA seq 500 aa AA seqDB search
MDHTEGSPAEEPPAHAPSPGKFGERPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSY
GNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGK
NYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLC
IASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFFIHLLDDDESEGEEFTVRDG
YIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCL
SQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESL
QLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQ
PVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPPNESNTNSEGS
YTNASTNSTSVTSSTATVVS
NT seq 1503 nt NT seq  +upstreamnt  +downstreamnt
atggaccacacggagggctcgcccgcggaggagccgcctgcgcatgctccatcgcctggg
aaatttggtgagcggcctccacctaaacgacttactagggaagctatgcgaaattattta
aaagagcgaggggatcaaacagtacttattcttcatgcaaaagttgcacagaagtcatat
ggaaatgaaaaaaggtttttttgcccacctccttgtgtatatcttatgggcagtggatgg
aagaaaaaaaaagaacaaatggaacgcgatggttgttctgaacaagagtctcaaccgtgt
gcatttattgggataggaaatagtgaccaagaaatgcagcagctaaacttggaaggaaag
aactattgcacagccaaaacattgtatatatctgactcagacaagcgaaagcacttcatg
ttgtctgtaaagatgttctatggcaacagtgatgacattggtgtgttcctcagcaagcgg
ataaaagtcatctccaaaccttccaaaaagaagcagtcattgaaaaatgctgacttatgc
attgcctcaggaacaaaggtggctctgtttaatcgactacgatcccagacagttagtacc
agatacttgcatgtagaaggaggtaattttcatgccagttcacagcagtggggagccttt
tttattcatctcttggatgatgatgaatcagaaggagaagaattcacagtccgagatggc
tacatccattatggacaaacagtcaaacttgtgtgctcagttactggcatggcactccca
agattgataattaggaaagttgataagcagaccgcattattggatgcagatgatcctgtg
tcacaactccataaatgtgcattttaccttaaggatacagaaagaatgtatttgtgcctt
tctcaagaaagaataattcaatttcaggccactccatgtccaaaagaaccaaataaagag
atgataaatgatggcgcttcctggacaatcattagcacagataaggcagagtatacattt
tatgagggaatgggccctgtccttgccccagtcactcctgtgcctgtggtagagagcctt
cagttgaatggcggtggggacgtagcaatgcttgaacttacaggacagaatttcactcca
aatttacgagtgtggtttggggatgtagaagctgaaactatgtacaggtgtggagagagt
atgctctgtgtcgtcccagacatttctgcattccgagaaggttggagatgggtccggcaa
ccagtccaggttccagtaactttggtccgaaatgatggaatcatttattccaccagcctt
acctttacctacacaccagaaccagggccgcggccacattgcagtgcagcaggagcaatc
cttcgagccaattcaagccaggtgccccctaacgaatcaaacacaaacagcgagggaagt
tacacaaacgccagcacaaattcaaccagtgtcacatcatctacagccacagtggtatcc
taa

KEGG   Homo sapiens (human): 11317Help
Entry
11317             CDS       T01001                                 

Gene name
RBPJL, RBPL, RBPSUHL, SUHL
Definition
(RefSeq) recombination signal binding protein for immunoglobulin kappa J region like
  KO
K06053  recombining binding protein suppressor of hairless
Organism
hsa  Homo sapiens (human)
Pathway
hsa04330  Notch signaling pathway
hsa04658  Th1 and Th2 cell differentiation
hsa05017  Spinocerebellar ataxia
hsa05165  Human papillomavirus infection
hsa05169  Epstein-Barr virus infection
hsa05203  Viral carcinogenesis
Network
nt06116  NOTCH signaling (viruses)
nt06166  Human papillomavirus (HPV)
  Element
N00380  HPV E6 to Notch signaling pathway
N00381  HPV E6 to Notch signaling pathway
N00382  HPV E6 to Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    11317 (RBPJL)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    11317 (RBPJL)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    11317 (RBPJL)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    11317 (RBPJL)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    11317 (RBPJL)
   05165 Human papillomavirus infection
    11317 (RBPJL)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    11317 (RBPJL)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Other transcription factors
   Others
    11317 (RBPJL)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: BTD LAG1-DNAbind
Motif
Other DBs
NCBI-GeneID: 11317
NCBI-ProteinID: NP_055091
OMIM: 616104
HGNC: 13761
Ensembl: ENSG00000124232
Vega: OTTHUMG00000033055
Pharos: Q9UBG7(Tbio)
UniProt: Q9UBG7
LinkDB All DBs
Position
20q13.12
AA seq 517 aa AA seqDB search
MDPAGAADPSVPPNPLTHLSLQDRSEMQLQSEADRRSLPGTWTRSSPEHTTILRGGVRRC
LQQQCEQTVRILHAKVAQKSYGNEKRFFCPPPCVYLSGPGWRVKPGQDQAHQAGETGPTV
CGYMGLDSASGSATETQKLNFEQQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGRE
LGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVA
SARQWAAFTLHLADGHSAQGDFPPREGYVRYGSLVQLVCTVTGITLPPMIIRKVAKQCAL
LDVDEPISQLHKCAFQFPGSPPGGGGTYLCLATEKVVQFQASPCPKEANRALLNDSSCWT
IIGTESVEFSFSTSLACTLEPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDV
EAETMYRSPRSLVCVVPDVAAFCSDWRWLRAPITIPMSLVRADGLFYPSAFSFTYTPEYS
VRPGHPGVPEPATDADALLESIHQEFTRTNFHLFIQT
NT seq 1554 nt NT seq  +upstreamnt  +downstreamnt
atggaccccgcaggggcagcagacccctcagtgcctcccaatcctttgactcacctgagc
ctgcaggacagatcagagatgcagctgcagagcgaagccgacaggcggagcctcccgggc
acttggaccaggtcatccccagagcacaccaccattctgaggggaggcgtgcgcaggtgc
ctgcagcaacagtgtgaacagactgtgcggatcctgcatgccaaggtggcccagaaatca
tacggaaatgagaagcggttcttctgccccccgccctgtgtctacctctcggggcctggc
tggagggtgaagccagggcaggatcaagctcaccaggcgggggaaacggggcccacggtc
tgcggttacatgggactggacagcgcgtccggcagcgccactgagacgcagaagctgaat
ttcgagcagcagccggactccagggaattcggctgcgccaagaccctgtacatctcagat
gcagacaagaggaagcactttcggctggtgctgcggctggtgctgcgcgggggccgggag
ctgggtaccttccacagccgccttatcaaggtcatctcgaagccctcgcagaagaagcag
tcgctgaaaaacaccgatctgtgcatatcctccggctcaaaggtctccctcttcaaccgc
ctgcgctctcagacggtctccacacgctacctctctgtggaggatggggcctttgtggcc
agtgcacgacagtgggctgccttcacgctccacctggctgatgggcactctgcccaagga
gacttcccaccgcgagagggctacgttcgctatggctccctggtgcagctcgtctgcacg
gtcaccggcatcacactacctcccatgatcatccgtaaagtagcaaaacagtgtgcgctc
cttgatgtggatgagcccatctcccagctgcacaagtgtgcattccagtttccaggcagt
cccccaggagggggtggcacctacttatgccttgccacagagaaggtggtgcaatttcag
gcctctccctgccccaaggaggcgaacagggctctgcttaacgacagctcttgctggacc
atcatcggcaccgagtcggtggaattttccttcagcaccagcctggcgtgtaccctggag
ccggtcactccggtgcctctcatcagcaccctagagctgagcggcgggggcgacgtggcc
acgctggagctccacggagagaacttccacgcggggctcaaggtgtggtttggggacgtg
gaggcagaaaccatgtacaggagcccgcggtccctggtgtgcgtggtgccggacgtggcg
gccttctgcagcgactggcgctggctgcgcgctcccatcacaatccccatgagcctggtg
cgcgccgacgggctcttctaccctagtgccttctccttcacctacaccccggaatacagc
gtgcggccgggtcaccccggcgtccccgagcccgccaccgacgccgacgcgctcctggag
agcatccatcaggagttcacgcgcaccaacttccacctcttcatccagacttag

KEGG   Homo sapiens (human): 9794Help
Entry
9794              CDS       T01001                                 

Gene name
MAML1, Mam-1, Mam1
Definition
(RefSeq) mastermind like transcriptional coactivator 1
  KO
K06061  mastermind
Organism
hsa  Homo sapiens (human)
Pathway
hsa04330  Notch signaling pathway
hsa04658  Th1 and Th2 cell differentiation
hsa05165  Human papillomavirus infection
Network
nt06116  NOTCH signaling (viruses)
nt06166  Human papillomavirus (HPV)
  Element
N00380  HPV E6 to Notch signaling pathway
N00381  HPV E6 to Notch signaling pathway
N00382  HPV E6 to Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    9794 (MAML1)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    9794 (MAML1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    9794 (MAML1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MamL-1 Kri1
Motif
Other DBs
NCBI-GeneID: 9794
NCBI-ProteinID: NP_055572
OMIM: 605424
HGNC: 13632
Ensembl: ENSG00000161021
Vega: OTTHUMG00000163237
Pharos: Q92585(Tbio)
UniProt: Q92585
LinkDB All DBs
Structure
PDB: 

Position
5q35.3
AA seq 1016 aa AA seqDB search
MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALH
QRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATS
PQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHS
LGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNL
MPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKT
EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS
PNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP
APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP
YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALM
AYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAV
SVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQ
QFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMP
MGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAH
IPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQ
HQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVG
SLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQA
YPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ
NT seq 3051 nt NT seq  +upstreamnt  +downstreamnt
atggtgctgcccacctgccccatggcggagttcgcgctgccgcggcacagcgcggtcatg
gagcgccttcgccggcgcatcgagctgtgccggcgccaccacagcacctgcgaggcccgc
tacgaggccgtgtcgcccgagcgcctggagctggagcgccaacacaccttcgccctgcac
cagcgctgcatccaggccaaggccaagcgcgccgggaagcacaggcagccgcccgccgcc
acggccccggcgcccgccgccccggccccgcgcctggacgccgctgacggccccgagcac
ggccgcccggccacgcatcttcatgatacagttaagaggaatcttgacagcgccacttcc
cctcagaatggcgatcaacagaatggctacggggacctctttcctgggcataagaagact
cgccgggaggcccctctgggagttgccatctcttccaatggactgcctccagcctccccc
ctcggtcagtctgacaagccttctggagccgacgccctgcagtccagtgggaagcactct
ctggggctagactctctcaacaaaaagcgtctggctgactccagccttcacttgaatgga
ggcagtaaccccagtgagtcatttcctctgagcctgaataaagaactgaagcaggagcct
gtcgaagacctgccttgcatgatcactgggactgtcggctccatatcgcaaagcaacctc
atgccagacctcaaccttaacgagcaggagtggaaggagctcatcgaggagctgaacagg
tcggtgcccgatgaagacatgaaggacctgtttaatgaggacttcgaggagaagaaggac
ccagagtcttctggctctgccacacaaacccccttggcacaggacattaatattaagacg
gaattctctccagcagcctttgagcaagaacagttaggctctccacaagtgagggccggg
tctgcagggcagacctttctggggccttcctctgcccctgtgagtacagattcccccagc
ctagggggctcccaaaccttattccacacctctggtcagccccgggcggacaatcccagt
ccaaacctgatgccggcatcagcccaggcccagaacgcacaaagagcccttgcaggtgtg
gtattgcccagtcagggcccaggaggggcctcagagctgtcctctgcccaccagctccag
cagatcgctgccaagcagaagcgcgagcagatgctccagaacccacagcaggccaccccg
gcaccagccccgggccagatgtccacatggcagcagacggggccctcccacagttcctta
gatgtcccttaccccatggagaagcctgccagcccttccagctacaagcaagacttcact
aactccaaactgctcatgatgcctagtgtgaataagagttcccctcggcccggaggcccc
tacctccagcccagccatgtgaacctgctgagtcaccagccaccgagtaacttgaatcag
aactccgcgaataaccaggggtctgtgctggactacggcaatacaaaacccctttctcat
tacaaagcggactgtgggcaaggcagcccggggtctggccagagcaagccagccctgatg
gcttatcttccccagcagctgtcccatataagtcacgagcagaactccctgtttctgatg
aagccaaagccaggaaatatgcctttccgatcactggttccacctggccaggagcagaac
ccttccagtgtccctgtgcaagcccaggctaccagtgttgggacccagccgcctgccgtg
tccgtggccagctcccacaacagctccccctatctcagcagccagcaacaggccgctgta
atgaagcagcatcagttgcttttggaccaacagaaacaaagggagcagcagcaaaagcat
ttacagcaacagcagttccttcagaggcaacagcaccttctcgcggaacaggagaagcaa
cagtttcagcgccatctgacccgcccaccaccccagtaccaagacccgacacaaggcagc
ttcccacagcaggttggacagttcacagggtcctctgctgccgtgcccggcatgaacacc
ttgggtccatccaactccagctgtcctcgagtgttccctcaggctgggaatctgatgcca
atgggccctggacatgcttcagtttcctctctccccacaaactcaggccaacaggaccgg
ggtgtggctcagttccctggctcccaaaacatgcctcagagcagcctctatggcatggct
tctggcataacccagatagttgcccagcccccgccacaggccaccaatggacatgcccac
attccacggcagaccaacgtgggccagaacacctccgtctcagctgcctatgggcagaac
tctctgggaagctctggcctctcccagcagcacaataaggggaccctgaaccctggttta
acaaagccaccggtcccaagggtgtcaccagccatgggaggccagaattcctcctggcag
catcagggaatgccgaacctcagtggccagaccccagggaacagcaacgtgagtcccttc
actgcagcctccagtttccacatgcagcagcaggcccacctgaaaatgtctagcccgcaa
ttctcccaggcagtgcccaacaggcccatggctcccatgagctcagcagctgccgtgggg
tccttgctacccccagtgagtgcacagcagaggaccagcgcccctgccccagcaccaccc
ccaacagcccctcagcagggcttgcctggcctgagcccagcagggcctgagctgggggcc
ttcagccagagccctgcctcacagatgggcggtcgggcggggctgcactgcacccaggcc
taccctgtgcggaccgcgggccaggagctgccttttgcctatagcgggcagccaggtggc
agtgggctctctagtgtggctggacacaccgatctgatcgactccctgctgaagaacagg
acttcagaggagtggatgagtgatttggacgacctgttagggtctcagtaa

KEGG   Homo sapiens (human): 84441Help
Entry
84441             CDS       T01001                                 

Gene name
MAML2, MAM-3, MAM2, MAM3, MLL-MAML2
Definition
(RefSeq) mastermind like transcriptional coactivator 2
  KO
K06061  mastermind
Organism
hsa  Homo sapiens (human)
Pathway
hsa04330  Notch signaling pathway
hsa04658  Th1 and Th2 cell differentiation
hsa05165  Human papillomavirus infection
Network
nt06116  NOTCH signaling (viruses)
nt06166  Human papillomavirus (HPV)
  Element
N00380  HPV E6 to Notch signaling pathway
N00381  HPV E6 to Notch signaling pathway
N00382  HPV E6 to Notch signaling pathway
Disease
H01508  Salivary gland cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    84441 (MAML2)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    84441 (MAML2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    84441 (MAML2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MamL-1
Motif
Other DBs
NCBI-GeneID: 84441
NCBI-ProteinID: NP_115803
OMIM: 607537
HGNC: 16259
Ensembl: ENSG00000184384
Vega: OTTHUMG00000167677
Pharos: Q8IZL2(Tbio)
UniProt: Q8IZL2
LinkDB All DBs
Position
11q21
AA seq 1156 aa AA seqDB search
MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYER
GRAESSDRERESTLQLLSLVQHGQGARKAGKHTKATATAATTTAPPPPPAAPPAASQAAA
TAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKRKQ
VVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPL
RKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQ
LMDPELQELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPME
KIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGA
SRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKI
PSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRS
FINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQ
QQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQ
QQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVG
QNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLAD
AEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHT
ILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLL
ANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSN
TTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQL
TPAVQMRPMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPP
SLTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDNMGPALNSDADFIDSLLKTEPGND
DWMKDINLDEILGNNS
NT seq 3471 nt NT seq  +upstreamnt  +downstreamnt
atgggggacacagcgcccccgcaggcccccgcaggagggctagggggggcctctggggcg
gggctccttggagggggctcagtcaccccgagagtgcacagtgctatcgtggagcgcctc
cgggctcggatcgctgtctgccgccaacaccacctgagctgtgaaggacgatatgaacga
ggtagggccgagagctcagaccgggaaagagaaagcaccttgcagctcctgagccttgta
cagcatggccagggggcaaggaaagctggcaaacacaccaaggccaccgccactgctgcc
accactacagcccctccaccgccccctgctgcccctcctgcggcctcccaagcagcagca
acagcagccccaccgcccccaccagactatcaccatcaccaccagcagcacctgctgaac
agtagcaataatggtggcagtggtgggataaacggagagcagcagccgcccgcttcaacc
ccaggggaccagaggaactcagccctgattgcgctccagggttccttgaaaagaaaacag
gtagttaacctatctcctgccaacagcaagcgacccaatggctttgtggacaactcattt
cttgatatcaaaagaattcgtgttggggagaatctctctgcaggacaaggtggcctccaa
ataaacaatggacaaagtcagattatgtcagggaccttgcctatgagccaagcacccctg
cgaaagactaacactctgccatcccatacacattctcctggcaatggcctgtttaacatg
ggcttaaaggaggtaaagaaggagccaggagagactctgtcttgcagtaagcacatggat
ggccaaatgacccaagagaatatttttcctaataggtacggagacgaccctggagaacaa
ctgatggatcctgagctgcaggaactgttcaatgaactgaccaacatatctgtgcctccc
atgagtgaccttgaactggagaacatgatcaatgccaccataaagcaggatgacccattt
aacattgacttgggtcagcaaagccagaggagcacacctaggccctccttacccatggag
aaaatagtgatcaaaagtgaatactcaccgggcttgactcagggcccctcaggctctcct
cagctgaggcccccatcagctggccccgcattctccatggccaactctgccctctccact
tcgtctccaatcccttcagtccctcagagccaggctcagcctcagacaggctccggagca
agccgggccttgccaagctggcaggaagtatcccatgcccagcagctcaaacagatagct
gctaatcgtcagcagcatgcccggatgcagcagcaccagcagcagcaccagcctaccaac
tggtcagccttgccctcttctgctggaccatcaccaggtccatttgggcaggagaaaatc
cccagcccttcttttggtcagcagacattcagcccacagagctcccccatgcctggggta
gctggcggcagcggccagtcgaaagtaatggctaactacatgtacaaggccggcccctca
gcccagggtgggcacctagatgtcctcatgcagcaaaagcctcaggatctcagtcgaagt
tttattaacaacccgcacccagccatggagccccgtcagggcaacaccaagcctttgttt
cattttaactcagatcaagcgaaccagcagatgccttctgttttgccttcccagaacaag
ccttctctcctacactacacccaacagcaacagcagcaacagcagcagcagcagcagcag
cagcagcagcagcagcagcaacagcagcagcagcagcaacagcaacagcaacagcaacag
cagagttcaatttcagctcaacaacagcaacagcagcagagctcaatttcagcccaacag
cagcagcagcagcaacaacagcagcagcagcagcaacaacaacagcaacaacagcagcag
cagcagcagcaacaaccatcttctcagcctgcccaatctctaccaagccagcctttgcta
aggtcacctttgccacttcagcaaaagctcctacttcagcaaatgcagaatcagcccatt
gcaggaatgggataccaagtctcccaacaacagagacaggatcaacactctgtggtaggc
cagaacacaggccccagtccaagtcctaacccctgctcaaatccaaacactggaagtggt
tacatgaactcccagcaatcactgttgaatcagcaattgatgggaaagaagcagactcta
cagaggcagatcatggagcagaaacagcaacttcttctccagcagcagatgctggctgac
gcggagaaaattgctccacaagatcagataaaccgacatttgtcaaggccacctccagat
tataaagaccaaagaagaaatgtgggcaatatgcaaccaactgctcagtattctggtggc
tcatccacaataagcttaaactctaaccaggctttggcaaacccagtttcaacacacacc
attttaactcccaattccagcctcctgtctacttctcacgggacaagaatgccatcatta
tctacagcagttcagaatatggggatgtatggaaatctgccttgtaatcaacctaacaca
tacagtgtcacttcaggaatgaatcaattgacccaacagagaaacccaaagcaattgtta
gcaaatcaaaacaaccctatgatgccacggccacctaccttagggccaagtaataataac
aatgtagccacttttggagctggatctgttggtaattcacaacaattgagaccaaattta
acccatagtatggcaagcatgccaccacagagaacatcaaacgtaatgatcacatccaac
acaactgcaccaaactgggcctctcaagaaggaacaagcaaacagcaagaagccctgacg
tctgcaggagtccgcttccccacaggtacacctgcagcctataccccaaatcagtcactg
caacaggcagtaggtagccagcaattttcccagagggcagtggctcctcctaaccagtta
acaccagcagtgcaaatgagacccatgaaccaaatgagccaaacactaaatgggcaaacc
atgggtcccctcaggggtctgaatctcagacccaatcagctaagcacacagattttgcct
aatttgaatcagtcaggaacagggttgaatcagtcgaggacgggcatcaaccagccacca
tccctgacgcccagcaattttccttcacccaaccaaagttccagggcttttcaaggaact
gaccacagcagtgacttagcttttgacttcctcagccaacaaaatgataacatgggccct
gccctaaacagtgatgctgatttcattgattctttattgaagacagagcctggtaatgat
gactggatgaaagacatcaatcttgatgaaatcttggggaacaattcctaa

KEGG   Homo sapiens (human): 55534Help
Entry
55534             CDS       T01001                                 

Gene name
MAML3, CAGH3, ERDA3, GDN, MAM-2, MAM2, TNRC3, mam-3
Definition
(RefSeq) mastermind like transcriptional coactivator 3
  KO
K06061  mastermind
Organism
hsa  Homo sapiens (human)
Pathway
hsa04330  Notch signaling pathway
hsa04658  Th1 and Th2 cell differentiation
hsa05165  Human papillomavirus infection
Network
nt06116  NOTCH signaling (viruses)
nt06166  Human papillomavirus (HPV)
  Element
N00380  HPV E6 to Notch signaling pathway
N00381  HPV E6 to Notch signaling pathway
N00382  HPV E6 to Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    55534 (MAML3)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    55534 (MAML3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    55534 (MAML3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MamL-1 Kin17_mid
Motif
Other DBs
NCBI-GeneID: 55534
NCBI-ProteinID: NP_061187
OMIM: 608991
HGNC: 16272
Ensembl: ENSG00000196782
Vega: OTTHUMG00000161441
Pharos: Q96JK9(Tbio)
UniProt: Q96JK9 Q9NPV6
LinkDB All DBs
Position
4q31.1
AA seq 1138 aa AA seqDB search
MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGP
GGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQ
RAKKSGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGA
CDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLL
EDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFS
DINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKSD
PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQT
PNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAK
LMQQKQQQQQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSP
MMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYG
NTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPR
AHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVS
GASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQQILAEQQLQ
QSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGP
SQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGP
RQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGA
QSWQQRSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRT
LNPAAMGRQMMPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQ
SQAYERNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
NT seq 3417 nt NT seq  +upstreamnt  +downstreamnt
atgggggatttcgcagcccccgctgctgccgcgaatggcagtagtatttgcatcaacagt
agcctgaacagcagcctcggcggggccgggatcggtgtgaataatactcccaatagtact
cccgctgctccgagtagcaatcacccggcagccggtggatgcggcggctccgggggcccc
ggcggcggttcggcggccgttcccaagcacagcaccgtggtggagcggctccgccagcgc
atcgagggctgccgtcggcaccacgtcaactgcgagaacaggtaccagcaggctcaggtg
gagcagctggagctggagcgccgggacaccgtgagcctctaccagcggaccctggagcag
agggccaagaaatcgggcgccggcaccggcaaacagcagcacccgagcaaaccccagcaa
gatgcggaggctgcctcggcggagcagaggaaccacacgctgatcatgctacaagagact
gtgaaaaggaagttggaaggagctcgatcaccacttaatggagaccagcagaatggtgct
tgtgatgggaatttttctccgactagcaaacgaattcgaaaggacatttctgcggggatg
gaagccatcaacaatttgcccagtaacatgccactgccttcagcttctcctcttcaccaa
cttgacctgaaaccttctttgcccttgcagaacagtggaactcacactcctgggcttcta
gaagatctaagtaagaatggtaggctccctgagattaaacttcctgtcaacggttgcagt
gacctggaggatagcttcaccatcttgcagagcaaagacctcaaacaagaacctctcgat
gaccctacttgcatagacacatcagaaacatctctttcaaatcagaacaagctgttctca
gacattaatctgaatgatcaggagtggcaagaattaatagatgaattggccaacacggtt
cctgaggatgacatacaggacctgttcaacgaagactttgaagagaagaaggagccagaa
ttctcgcagccagcaactgagacccctctctcccaggagagtgcgagcgtgaagagcgac
ccctctcactctcccttcgcacatgtctccatgggatctccccaggcgaggccttcttct
tctggtcctcccttttctactgtctccacggccactagtttaccttctgttgccagcact
cccgcagctccaaaccctgcaagctcaccagcaaactgtgctgtccagtcccctcaaact
ccaaaccaagcccacactccaggccaagctccacctcggcctggaaatggttatctcctg
aatccggcagcagtgacagtggccggttcagcgtcagggcctgtggctgtgcccagctct
gacatgtctccagcagaacagctcaaacagatggctgcacagcagcaacaaagggccaaa
ctcatgcagcagaaacagcaacagcaacagcagcagcagcagcagcagcagcagcagcag
cagcagcagcagcagcagcagcagcaacagcactcaaatcagacttcaaattggtctccc
ttaggacctccctctagtccatatggagcagcttttactgcagaaaaaccaaatagccca
atgatgtacccccaagcctttaacaaccaaaaccctatagtgcctccaatggcaaacaac
ctgcagaagacaacaatgaataactacctccctcagaatcacatgaatatgatcaatcag
cagccaaataacttgggtacaaactccttaaacaaacagcacaatattctgacttatggc
aacactaaacccctgacccacttcaatgcagacctgagtcagaggatgacaccaccagtg
gccaaccccaacaaaaaccccttgatgccgtatatccagcagcagcaacagcagcagcaa
cagcaacagcagcagcagcagcagcagcagccgccacctccacagctccaggcccccagg
gcacacctgagcgaagaccagaaacgcctgcttctcatgaagcagaaaggagtgatgaat
cagcccatggcttacgctgcacttccatcccacggtcaggagcagcatccagttggactt
ccccgaaccacaggccccatgcagtcctccgtgcccccaggctcaggtggcatggtctca
ggagccagtcccgcaggccccggcttcctgggcagccagccccaagcagccatcatgaag
cagatgctcattgatcagcgggcccagttgatagagcagcagaagcaacagttcctgcgg
gagcaaaggcagcagcagcagcagcagcagcagcagattttggcggaacagcagttgcag
caatcacatctaccccggcagcacctccagccacagcggaatccatacccagtgcagcag
gtcaatcagtttcaaggttctccccaggatatagcagccgtaagaagccaagcagccctc
cagagcatgcgaacgtcacggctgatggcacagaacgcaggcatgatgggaataggaccc
tcccagaaccctgggacgatggccaccgcagctgcgcagtcggagatgggactggcccct
tatagcaccacgcctaccagccaaccaggaatgtacaatatgagcacaggcatgacccaa
atgttgcagcatccaaaccaaagtggcatgagcatcacacataaccaagcccagggaccg
aggcaacctgcctctgggcagggggttggaatggtgagtggctttggtcagagcatgctg
gtgaactcagccattacccagcaacatccacagatgaaagggccagtaggccaggccttg
cctaggccccaagcccctccaaggctgcagagccttatgggaacagtccagcaaggagca
caaagctggcaacagaggagcttgcagggcatgcctgggaggactagtggagaattggga
ccattcaacaatggcgccagctaccctcttcaagctgggcagccgagactgaccaagcag
cacttcccacagggactgagccagtcagtcgtggatgctaacacgggcacagtgaggacc
ctcaacccagctgccatgggtcggcagatgatgccatcgctcccggggcagcaaggcacc
agccaggcgaggccaatggtcatgtctggcctgagccagggagtcccaggcatgccagcg
ttcagccagcccccagcacagcagcagatacccagtggcagctttgctccaagcagccag
agccaagcctatgagcggaatgcccctcaggacgtgtcatacaattacagtggcgacgga
gctgggggttccttccctggcctcccggacggtgcagaccttgtggactccatcatcaaa
ggcgggccaggggacgagtggatgcaggagcttgatgaattgtttggtaacccctaa

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