Homo sapiens (human): 3586 Entry 3586              CDS       T01001                                  Gene name IL10, CSIF, GVHDS, IL-10, IL10A, TGIF Definition (RefSeq) interleukin 10   KO K05443   interleukin 10 Organism hsa  Homo sapiens (human) Pathway hsa04060   Cytokine-cytokine receptor interaction hsa04068   FoxO signaling pathway hsa04625   C-type lectin receptor signaling pathway hsa04630   Jak-STAT signaling pathway hsa04660   T cell receptor signaling pathway hsa04672   Intestinal immune network for IgA production hsa05133   Pertussis hsa05140   Leishmaniasis hsa05142   Chagas disease (American trypanosomiasis) hsa05143   African trypanosomiasis hsa05144   Malaria hsa05145   Toxoplasmosis hsa05146   Amoebiasis hsa05150   Staphylococcus aureus infection hsa05152   Tuberculosis hsa05310   Asthma hsa05320   Autoimmune thyroid disease hsa05321   Inflammatory bowel disease (IBD) hsa05322   Systemic lupus erythematosus hsa05330   Allograft rejection Network N00415   IL10-Jak-STAT signaling pathway Disease H00083   Allograft rejection H00084   Graft-versus-host disease H01227   Inflammatory bowel disease (IBD) H01359   Anaphylaxis H01466   Ulcerative colitis H01468   Eosinophilic granulomatosis with polyangiitis H01476   Behcet disease Drug target Pirfenidone:  D01583 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 Jak-STAT signaling pathway     3586 (IL10)    04068 FoxO signaling pathway     3586 (IL10)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     3586 (IL10)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     3586 (IL10)    04660 T cell receptor signaling pathway     3586 (IL10)    04672 Intestinal immune network for IgA production     3586 (IL10)  09160 Human Diseases   09163 Immune diseases    05310 Asthma     3586 (IL10)    05322 Systemic lupus erythematosus     3586 (IL10)    05320 Autoimmune thyroid disease     3586 (IL10)    05321 Inflammatory bowel disease (IBD)     3586 (IL10)    05330 Allograft rejection     3586 (IL10)   09171 Infectious diseases: Bacterial    05133 Pertussis     3586 (IL10)    05150 Staphylococcus aureus infection     3586 (IL10)    05152 Tuberculosis     3586 (IL10)   09174 Infectious diseases: Parasitic    05146 Amoebiasis     3586 (IL10)    05144 Malaria     3586 (IL10)    05145 Toxoplasmosis     3586 (IL10)    05140 Leishmaniasis     3586 (IL10)    05142 Chagas disease (American trypanosomiasis)     3586 (IL10)    05143 African trypanosomiasis     3586 (IL10)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hsa04052]     3586 (IL10)    00536 Glycosaminoglycan binding proteins [BR:hsa00536]     3586 (IL10) Cytokines and growth factors [BR:hsa04052]  Cytokines   Interleukins    3586 (IL10) Glycosaminoglycan binding proteins [BR:hsa00536]  Heparan sulfate/Haparin   Cytokines    3586 (IL10) SSDB Motif Pfam:  IL10 IL22 TSA Other DBs NCBI-GeneID:  3586 NCBI-ProteinID:  NP_000563 OMIM:  124092 HGNC:  5962 Ensembl:  ENSG00000136634 Vega:  OTTHUMG00000036386 Pharos:  P22301(Tbio) UniProt:  P22301 Q6FGW4 LinkDB Structure PDB:  2ILK 1ILK 1LK3 2H24 1INR 1Y6K 1J7V Position 1q32.1 AA seq 178 aa MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQ LDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKTLR LRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN NT seq 537 nt   +upstreamnt  +downstreamnt atgcacagctcagcactgctctgttgcctggtcctcctgactggggtgagggccagccca ggccagggcacccagtctgagaacagctgcacccacttcccaggcaacctgcctaacatg cttcgagatctccgagatgccttcagcagagtgaagactttctttcaaatgaaggatcag ctggacaacttgttgttaaaggagtccttgctggaggactttaagggttacctgggttgc caagccttgtctgagatgatccagttttacctggaggaggtgatgccccaagctgagaac caagacccagacatcaaggcgcatgtgaactccctgggggagaacctgaagaccctcagg ctgaggctacggcgctgtcatcgatttcttccctgtgaaaacaagagcaaggccgtggag caggtgaagaatgcctttaataagctccaagagaaaggcatctacaaagccatgagtgag tttgacatcttcatcaactacatagaagcctacatgacaatgaagatacgaaactga

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