| Entry |
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| Gene name |
IL10, CSIF, GVHDS, IL-10, IL10A, TGIF
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| Definition |
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| KO |
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| Organism |
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| Pathway |
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa04061 | Viral protein interaction with cytokine and cytokine receptor |
| hsa04625 | C-type lectin receptor signaling pathway |
| hsa04660 | T cell receptor signaling pathway |
| hsa04672 | Intestinal immune network for IgA production |
| hsa05150 | Staphylococcus aureus infection |
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| Network |
nt06119 JAK-STAT signaling (viruses) nt06150 Cytokine-cytokine receptor interaction (viruses) nt06167 Human cytomegalovirus (HCMV) |
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| Element |
| N00415 | IL10-Jak-STAT signaling pathway |
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| Disease |
| H00084 | Graft-versus-host disease |
| H01227 | Inflammatory bowel disease (IBD) |
| H01468 | Eosinophilic granulomatosis with polyangiitis |
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| Drug target |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
3586 (IL10)
04068 FoxO signaling pathway
3586 (IL10)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
3586 (IL10)
04061 Viral protein interaction with cytokine and cytokine receptor
3586 (IL10)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
3586 (IL10)
04660 T cell receptor signaling pathway
3586 (IL10)
04672 Intestinal immune network for IgA production
3586 (IL10)
09160 Human Diseases
09171 Infectious disease: bacterial
05135 Yersinia infection
3586 (IL10)
05133 Pertussis
3586 (IL10)
05150 Staphylococcus aureus infection
3586 (IL10)
05152 Tuberculosis
3586 (IL10)
09174 Infectious disease: parasitic
05146 Amoebiasis
3586 (IL10)
05144 Malaria
3586 (IL10)
05145 Toxoplasmosis
3586 (IL10)
05140 Leishmaniasis
3586 (IL10)
05142 Chagas disease
3586 (IL10)
05143 African trypanosomiasis
3586 (IL10)
09163 Immune disease
05310 Asthma
3586 (IL10)
05322 Systemic lupus erythematosus
3586 (IL10)
05320 Autoimmune thyroid disease
3586 (IL10)
05321 Inflammatory bowel disease
3586 (IL10)
05330 Allograft rejection
3586 (IL10)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and growth factors [BR:hsa04052]
3586 (IL10)
00536 Glycosaminoglycan binding proteins [BR:hsa00536]
3586 (IL10)
Cytokines and growth factors [BR:hsa04052]
Cytokines
Interleukins
3586 (IL10)
Glycosaminoglycan binding proteins [BR:hsa00536]
Heparan sulfate / Heparin
Cytokines
3586 (IL10)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Structure |
PDB: |
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| Position |
1q32.1
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| AA seq |
178 aa
MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQ
LDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKTLR
LRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN |
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| NT seq |
537 nt +upstreamnt +downstreamnt
atgcacagctcagcactgctctgttgcctggtcctcctgactggggtgagggccagccca
ggccagggcacccagtctgagaacagctgcacccacttcccaggcaacctgcctaacatg
cttcgagatctccgagatgccttcagcagagtgaagactttctttcaaatgaaggatcag
ctggacaacttgttgttaaaggagtccttgctggaggactttaagggttacctgggttgc
caagccttgtctgagatgatccagttttacctggaggaggtgatgccccaagctgagaac
caagacccagacatcaaggcgcatgtgaactccctgggggagaacctgaagaccctcagg
ctgaggctacggcgctgtcatcgatttcttccctgtgaaaacaagagcaaggccgtggag
caggtgaagaatgcctttaataagctccaagagaaaggcatctacaaagccatgagtgag
tttgacatcttcatcaactacatagaagcctacatgacaatgaagatacgaaactga |
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