Homo sapiens (human): 3665
Entry
3665 CDS
T01001
Gene name
IRF7, IMD39, IRF-7, IRF-7H, IRF7A, IRF7B, IRF7C, IRF7H
Definition
(RefSeq) interferon regulatory factor 7
KO
K09447
interferon regulatory factor 7
Organism
hsa
Homo sapiens (human)
Pathway
hsa04620
Toll-like receptor signaling pathway
hsa04621
NOD-like receptor signaling pathway
hsa04622
RIG-I-like receptor signaling pathway
hsa04623
Cytosolic DNA-sensing pathway
hsa05160
Hepatitis C
hsa05161
Hepatitis B
hsa05162
Measles
hsa05164
Influenza A
hsa05167
Kaposi sarcoma-associated herpesvirus infection
hsa05168
Herpes simplex virus 1 infection
hsa05169
Epstein-Barr virus infection
hsa05203
Viral carcinogenesis
Network
nt06121
TLR signaling (viruses and bacteria)
nt06122
IFN signaling (viruses)
nt06133
RIG-I signaling (viruses)
nt06162
Hepatitis B virus (HBV)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06166
Human papillomavirus (HPV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06169
Measles virus (MV)
nt06170
Influenza A virus (IAV)
nt06221
TLR signaling
nt06222
IFN signaling
nt06263
Hepatocellular carcinoma
Element
N00148
TLR3-IRF7 signaling pathway
N00150
Type I IFN signaling pathway
N00162
KSHV vIRF3 to TLR3-IRF7 signaling pathway
N00163
KSHV KIE1/2 to TLR3-IRF7 signaling pathway
N00261
KSHV vIRF2 to IFN signaling pathway
N00268
HBV HBx to RIG-I-like receptor signaling pathway
N00271
HCV NS3/4A to RIG-I-like receptor signaling pathway
N00469
RIG-I-IRF7/3 signaling pathway
N00471
EBV LMP2A/2B to IFN signaling pathway
N00472
EBV LMP1 to IFN signaling pathway
N00473
EBV BGLF4 to IFN signaling pathway
N00516
HCV NS3/4A to TLR3-IRF3 signaling pathway
N00553
TLR4-IRF3/7 signaling pathway
N00554
HBV HBe to TLR4-IRF3/7 signaling pathway
N00555
HBV HBe to TLR4-IRF3/7 signaling pathway
N00565
HSV US11 to RIG-I-like receptor signaling pathway
N00566
HSV UL36USP to RIG-I-like receptor signaling pathway
N00567
HSV ICP34.5 to TBK1 signaling pathway
N00685
MV V to RIG-I-IRF7/3 signaling pathway
N00690
TLR7/9-IRF7 signaling pathway
N00691
MV V to TLR7/9-IRF7 signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
3665 (IRF7)
04621 NOD-like receptor signaling pathway
3665 (IRF7)
04622 RIG-I-like receptor signaling pathway
3665 (IRF7)
04623 Cytosolic DNA-sensing pathway
3665 (IRF7)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
3665 (IRF7)
09172 Infectious disease: viral
05162 Measles
3665 (IRF7)
05164 Influenza A
3665 (IRF7)
05161 Hepatitis B
3665 (IRF7)
05160 Hepatitis C
3665 (IRF7)
05168 Herpes simplex virus 1 infection
3665 (IRF7)
05167 Kaposi sarcoma-associated herpesvirus infection
3665 (IRF7)
05169 Epstein-Barr virus infection
3665 (IRF7)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
3665 (IRF7)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Helix-turn-helix
Tryptophan clusters interferon-regulating factors
3665 (IRF7)
SSDB
Motif
Pfam:
IRF-3
IRF
Other DBs
NCBI-GeneID:
3665
NCBI-ProteinID:
NP_001563
OMIM:
605047
HGNC:
6122
Ensembl:
ENSG00000185507
Vega:
OTTHUMG00000132019
Pharos:
Q92985
(Tbio)
UniProt:
Q92985
LinkDB
Position
11p15.5
AA seq
503 aa
MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIF
KAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHK
VYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKG
DLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAV
ETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTV
LQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLE
LRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRAR
QRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSL
CLSSANSLYDDIECFLMELEQPA
NT seq
1512 nt
+upstream
nt +downstream
nt
atggccttggctcctgagagggcagccccacgcgtgctgttcggagagtggctccttgga
gagatcagcagcggctgctatgaggggctgcagtggctggacgaggcccgcacctgtttc
cgcgtgccctggaagcacttcgcgcgcaaggacctgagcgaggccgacgcgcgcatcttc
aaggcctgggctgtggcccgcggcaggtggccgcctagcagcaggggaggtggcccgccc
cccgaggctgagactgcggagcgcgccggctggaaaaccaacttccgctgcgcactgcgc
agcacgcgtcgcttcgtgatgctgcgggataactcgggggacccggccgacccgcacaag
gtgtacgcgctcagccgggagctgtgctggcgagaaggcccaggcacggaccagactgag
gcagaggcccccgcagctgtcccaccaccacagggtgggcccccagggccattcctggca
cacacacatgctggactccaagccccaggccccctccctgccccagctggtgacaagggg
gacctcctgctccaggcagtgcaacagagctgcctggcagaccatctgctgacagcgtca
tggggggcagatccagtcccaaccaaggctcctggagagggacaagaagggcttcccctg
actggggcctgtgctggaggcccagggctccctgctggggagctgtacgggtgggcagta
gagacgacccccagccccgggccccagcccgcggcactaacgacaggcgaggccgcggcc
ccagagtccccgcaccaggcagagccgtacctgtcaccctccccaagcgcctgcaccgcg
gtgcaagagcccagcccaggggcgctggacgtgaccatcatgtacaagggccgcacggtg
ctgcagaaggtggtgggacacccgagctgcacgttcctatacggccccccagacccagct
gtccgggccacagacccccagcaggtagcattccccagccctgccgagctcccggaccag
aagcagctgcgctacacggaggaactgctgcggcacgtggcccctgggttgcacctggag
cttcgggggccacagctgtgggcccggcgcatgggcaagtgcaaggtgtactgggaggtg
ggcggacccccaggctccgccagcccctccaccccagcctgcctgctgcctcggaactgt
gacacccccatcttcgacttcagagtcttcttccaagagctggtggaattccgggcacgg
cagcgccgtggctccccacgctataccatctacctgggcttcgggcaggacctgtcagct
gggaggcccaaggagaagagcctggtcctggtgaagctggaaccctggctgtgccgagtg
cacctagagggcacgcagcgtgagggtgtgtcttccctggatagcagcagcctcagcctc
tgcctgtccagcgccaacagcctctatgacgacatcgagtgcttccttatggagctggag
cagcccgcctag
Homo sapiens (human): 3661
Entry
3661 CDS
T01001
Gene name
IRF3, IIAE7
Definition
(RefSeq) interferon regulatory factor 3
KO
K05411
interferon regulatory factor 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04620
Toll-like receptor signaling pathway
hsa04621
NOD-like receptor signaling pathway
hsa04622
RIG-I-like receptor signaling pathway
hsa04623
Cytosolic DNA-sensing pathway
hsa05131
Shigellosis
hsa05133
Pertussis
hsa05135
Yersinia infection
hsa05160
Hepatitis C
hsa05161
Hepatitis B
hsa05162
Measles
hsa05163
Human cytomegalovirus infection
hsa05164
Influenza A
hsa05165
Human papillomavirus infection
hsa05167
Kaposi sarcoma-associated herpesvirus infection
hsa05168
Herpes simplex virus 1 infection
hsa05169
Epstein-Barr virus infection
hsa05170
Human immunodeficiency virus 1 infection
hsa05203
Viral carcinogenesis
Network
nt06121
TLR signaling (viruses and bacteria)
nt06133
RIG-I signaling (viruses)
nt06134
CGAS-STING signaling (viruses and bacteria)
nt06161
Human immunodeficiency virus type 1 (HIV-1)
nt06162
Hepatitis B virus (HBV)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06166
Human papillomavirus (HPV)
nt06167
Human cytomegalovirus (HCMV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06169
Measles virus (MV)
nt06170
Influenza A virus (IAV)
nt06221
TLR signaling
nt06263
Hepatocellular carcinoma
Element
N00149
TLR3-IRF3 signaling pathway
N00161
KSHV vIRF1/2 to TLR3-IRF3 signaling pathway
N00268
HBV HBx to RIG-I-like receptor signaling pathway
N00271
HCV NS3/4A to RIG-I-like receptor signaling pathway
N00346
HPV E6 to TLR-IRF3 signaling pathway
N00395
cGAS-STING signaling pathway
N00396
HCMV UL82 to cGAS-STING signaling pathway
N00440
HIV Vpu/Vif/Vpr to cGAS-STING signaling pathway
N00469
RIG-I-IRF7/3 signaling pathway
N00470
EBV BGLF4 to RIG-I-like receptor signaling pathway
N00516
HCV NS3/4A to TLR3-IRF3 signaling pathway
N00517
HCV NS3/4A to TLR3-IRF3 signaling pathway
N00552
HBV pol to TLR3-IRF3 signaling pathway
N00553
TLR4-IRF3/7 signaling pathway
N00554
HBV HBe to TLR4-IRF3/7 signaling pathway
N00555
HBV HBe to TLR4-IRF3/7 signaling pathway
N00565
HSV US11 to RIG-I-like receptor signaling pathway
N00566
HSV UL36USP to RIG-I-like receptor signaling pathway
N00567
HSV ICP34.5 to TBK1 signaling pathway
N00568
HSV US3 to IRF3 signaling pathway
N00569
HSV UL41 to cGAS-STING signaling pathway
N00570
HSV ICP0 to cGAS-STING signaling pathway
N00685
MV V to RIG-I-IRF7/3 signaling pathway
N00686
MV N to RIG-I-IRF7/3 signaling pathway
N00687
MV V/C to RIG-I-IRF7/3 signaling pathway
N00727
IAV NS1 to RIG-I-like receptor signaling pathway
N00728
IAV NS1 to RIG-I-like receptor signaling pathway
N00729
IAV NS1 to RIG-I-like receptor signaling pathway
N00732
IAV PB1-F2/PB2 to RIG-I-like receptor signaling pathway
N00734
IAV PB1-F2/PB2 to RIG-I-like receptor signaling pathway
N00946
Shigella IpaJ to cGAS-STING signaling pathway
N00947
Shigella Ipa4.5 to cGAS-STING signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
3661 (IRF3)
04621 NOD-like receptor signaling pathway
3661 (IRF3)
04622 RIG-I-like receptor signaling pathway
3661 (IRF3)
04623 Cytosolic DNA-sensing pathway
3661 (IRF3)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
3661 (IRF3)
09171 Infectious disease: bacterial
05131 Shigellosis
3661 (IRF3)
05135 Yersinia infection
3661 (IRF3)
05133 Pertussis
3661 (IRF3)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
3661 (IRF3)
05162 Measles
3661 (IRF3)
05164 Influenza A
3661 (IRF3)
05161 Hepatitis B
3661 (IRF3)
05160 Hepatitis C
3661 (IRF3)
05168 Herpes simplex virus 1 infection
3661 (IRF3)
05163 Human cytomegalovirus infection
3661 (IRF3)
05167 Kaposi sarcoma-associated herpesvirus infection
3661 (IRF3)
05169 Epstein-Barr virus infection
3661 (IRF3)
05165 Human papillomavirus infection
3661 (IRF3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
3661 (IRF3)
04131 Membrane trafficking [BR:
hsa04131
]
3661 (IRF3)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Helix-turn-helix
Tryptophan clusters interferon-regulating factors
3661 (IRF3)
Membrane trafficking [BR:
hsa04131
]
Autophagy
Other autophagy associated proteins
TRIM-directed selective autophagy
3661 (IRF3)
SSDB
Motif
Pfam:
IRF-3
IRF
Other DBs
NCBI-GeneID:
3661
NCBI-ProteinID:
NP_001562
OMIM:
603734
HGNC:
6118
Ensembl:
ENSG00000126456
Vega:
OTTHUMG00000183287
Pharos:
Q14653
(Tbio)
UniProt:
Q14653
LinkDB
Structure
PDB:
5JEL
5JEO
3A77
5JEJ
1QWT
3QU6
1J2F
2PI0
1ZOQ
5JEK
5JEM
5JER
1T2K
2O6G
Position
19q13.33
AA seq
427 aa
MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA
TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP
DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT
PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG
WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL
PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK
RLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMD
FQGPGES
NT seq
1284 nt
+upstream
nt +downstream
nt
atgggaaccccaaagccacggatcctgccctggctggtgtcgcagctggacctggggcaa
ctggagggcgtggcctgggtgaacaagagccgcacgcgcttccgcatcccttggaagcac
ggcctacggcaggatgcacagcaggaggatttcggaatcttccaggcctgggccgaggcc
actggtgcatatgttcccgggagggataagccagacctgccaacctggaagaggaatttc
cgctctgccctcaaccgcaaagaagggttgcgtttagcagaggaccggagcaaggaccct
cacgacccacataaaatctacgagtttgtgaactcaggagttggggacttttcccagcca
gacacctctccggacaccaatggtggaggcagtacttctgatacccaggaagacattctg
gatgagttactgggtaacatggtgttggccccactcccagatccgggacccccaagcctg
gctgtagcccctgagccctgccctcagcccctgcggagccccagcttggacaatcccact
cccttcccaaacctggggccctctgagaacccactgaagcggctgttggtgccgggggaa
gagtgggagttcgaggtgacagccttctaccggggccgccaagtcttccagcagaccatc
tcctgcccggagggcctgcggctggtggggtccgaagtgggagacaggacgctgcctgga
tggccagtcacactgccagaccctggcatgtccctgacagacaggggagtgatgagctac
gtgaggcatgtgctgagctgcctgggtgggggactggctctctggcgggccgggcagtgg
ctctgggcccagcggctggggcactgccacacatactgggcagtgagcgaggagctgctc
cccaacagcgggcatgggcctgatggcgaggtccccaaggacaaggaaggaggcgtgttt
gacctggggcccttcattgtagatctgattaccttcacggaaggaagcggacgctcacca
cgctatgccctctggttctgtgtgggggagtcatggccccaggaccagccgtggaccaag
aggctcgtgatggtcaaggttgtgcccacgtgcctcagggccttggtagaaatggcccgg
gtagggggtgcctcctccctggagaatactgtggacctgcacatttccaacagccaccca
ctctccctcacctccgaccagtacaaggcctacctgcaggacttggtggagggcatggat
ttccagggccctggggagagctga
DBGET
integrated database retrieval system
