Homo sapiens (human): 3696
Entry
3696 CDS
T01001
Gene name
ITGB8
Definition
(RefSeq) integrin subunit beta 8
KO
K06591
integrin beta 8
Organism
hsa
Homo sapiens (human)
Pathway
hsa04151
PI3K-Akt signaling pathway
hsa04510
Focal adhesion
hsa04512
ECM-receptor interaction
hsa04514
Cell adhesion molecules (CAMs)
hsa04810
Regulation of actin cytoskeleton
hsa05165
Human papillomavirus infection
hsa05410
Hypertrophic cardiomyopathy (HCM)
hsa05412
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
hsa05414
Dilated cardiomyopathy (DCM)
Network
nt06135
Cytoskeletal regulation (viruses)
nt06167
Human cytomegalovirus (HCMV)
Element
N00393
ITGA/B-RhoA signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
3696 (ITGB8)
09133 Signaling molecules and interaction
04512 ECM-receptor interaction
3696 (ITGB8)
04514 Cell adhesion molecules (CAMs)
3696 (ITGB8)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
3696 (ITGB8)
09142 Cell motility
04810 Regulation of actin cytoskeleton
3696 (ITGB8)
09160 Human Diseases
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy (HCM)
3696 (ITGB8)
05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
3696 (ITGB8)
05414 Dilated cardiomyopathy (DCM)
3696 (ITGB8)
09172 Infectious disease: viral
05165 Human papillomavirus infection
3696 (ITGB8)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
3696 (ITGB8)
04515 Cell adhesion molecules [BR:
hsa04515
]
3696 (ITGB8)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
3696 (ITGB8)
Cell adhesion molecules [BR:
hsa04515
]
Integrins
Integrin beta subunits
3696 (ITGB8)
SSDB
Motif
Pfam:
Integrin_beta
PSI_integrin
EGF_2
Sigma_reg_N
Other DBs
NCBI-GeneID:
3696
NCBI-ProteinID:
NP_002205
OMIM:
604160
HGNC:
6163
Ensembl:
ENSG00000105855
Vega:
OTTHUMG00000023594
Pharos:
P26012
(Tbio)
UniProt:
P26012
Q9BUG9
LinkDB
Structure
PDB:
6DJP
Position
7p21.1
AA seq
769 aa
MCGSALAFFTAAFVCLQNDRRGPASFLWAAWVFSLVLGLGQGEDNRCASSNAASCARCLA
LGPECGWCVQEDFISGGSRSERCDIVSNLISKGCSVDSIEYPSVHVIIPTENEINTQVTP
GEVSIQLRPGAEANFMLKVHPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAFF
SRDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFEKA
VHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIV
VPNDGNCHLKNNVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPG
TIAGEIESKAANLNNLVVEAYQKLISEVKVQVENQVQGIYFNITAICPDGSRKPGMEGCR
NVTSNDEVLFNVTVTMKKCDVTGGKNYAIIKPIGFNETAKIHIHRNCSCQCEDNRGPKGK
CVDETFLDSKCFQCDENKCHFDEDQFSSESCKSHKDQPVCSGRGVCVCGKCSCHKIKLGK
VYGKYCEKDDFSCPYHHGNLCAGHGECEAGRCQCFSGWEGDRCQCPSAAAQHCVNSKGQV
CSGRGTCVCGRCECTDPRSIGRFCEHCPTCYTACKENWNCMQCLHPHNLSQAILDQCKTS
CALMEQQHYVDQTSECFSSPSYLRIFFIIFIVTFLIGLLKVLIIRQVILQWNSNKIKSSS
DYRVSASKKDKLILQSVCTRAVTYRREKPEEIKMDISKLNAHETFRCNF
NT seq
2310 nt
+upstream
nt +downstream
nt
atgtgcggctcggccctggctttttttaccgctgcatttgtctgcctgcaaaacgaccgg
cgaggtcccgcctcgttcctctgggcagcctgggtgttttcacttgttcttggactgggc
caaggtgaagacaatagatgtgcatcttcaaatgcagcatcctgtgccaggtgccttgcg
ctgggtccagaatgtggatggtgtgttcaagaggatttcatttcaggtggatcaagaagt
gaacgttgtgatattgtttccaatttaataagcaaaggctgctcagttgattcaatagaa
tacccatctgtgcatgttataatacccactgaaaatgaaattaatacccaggtgacacca
ggagaagtgtctatccagctgcgtccaggagccgaagctaattttatgctgaaagttcat
cctctgaagaaatatcctgtggatctttattatcttgttgatgtctcagcatcaatgcac
aataatatagaaaaattaaattccgttggaaacgatttatctagaaaaatggcatttttc
tcccgtgactttcgtcttggatttggctcatacgttgataaaacagtttcaccatacatt
agcatccaccccgaaaggattcataatcaatgcagtgactacaatttagactgcatgcct
ccccatggatacatccatgtgctgtctttgacagagaacatcactgagtttgagaaagca
gttcatagacagaagatctctggaaacatagatacaccagaaggaggttttgacgccatg
cttcaggcagctgtctgtgaaagtcatatcggatggcgaaaagaggctaaaagattgctg
ctggtgatgacagatcagacgtctcatctcgctcttgatagcaaattggcaggcatagtg
gtgcccaatgacggaaactgtcatctgaaaaacaacgtctatgtcaaatcgacaaccatg
gaacacccctcactaggccaactttcagagaaattaatagacaacaacattaatgtcatc
tttgcagttcaaggaaaacaatttcattggtataaggatcttctacccctcttgccaggc
accattgctggtgaaatagaatcaaaggctgcaaacctcaataatttggtagtggaagcc
tatcagaagctcatttcagaagtgaaagttcaggtggaaaaccaggtacaaggcatctat
tttaacattaccgccatctgtccagatgggtccagaaagccaggcatggaaggatgcaga
aacgtgacgagcaatgatgaagttcttttcaatgtaacagttacaatgaaaaaatgtgat
gtcacaggaggaaaaaactatgcaataatcaaacctattggttttaatgaaaccgctaaa
attcatatacacagaaactgcagctgtcagtgtgaggacaacagaggacctaaaggaaag
tgtgtagatgaaacttttctagattccaagtgtttccagtgtgatgagaataaatgtcat
tttgatgaagatcagttttcttctgagagttgcaagtcacacaaggatcagcctgtttgc
agtggtcgaggagtttgtgtttgtgggaaatgttcatgtcacaaaattaagcttggaaaa
gtgtatggaaaatactgtgaaaaggatgacttttcttgtccatatcaccatggaaatctg
tgtgctgggcatggagagtgtgaagcaggcagatgccaatgcttcagtggctgggaaggt
gatcgatgccagtgcccttcagcagcagcccagcactgtgtcaattcaaagggccaagtg
tgcagtggaagaggcacgtgtgtgtgtggaaggtgtgagtgcaccgatcccaggagcatc
ggccgcttctgtgaacactgccccacctgttatacagcctgcaaggaaaactggaattgt
atgcaatgccttcaccctcacaatttgtctcaggctatacttgatcagtgcaaaacctca
tgtgctctcatggaacaacagcattatgtcgaccaaacttcagaatgtttctccagccca
agctacttgagaatatttttcatcattttcatagttacattcttgattgggttgcttaaa
gtcctgatcattagacaggtgatactacaatggaatagtaataaaattaagtcctcatca
gattacagagtgtcagcctcaaaaaaggataagttgattctgcaaagtgtttgcacaaga
gcagtcacctaccgacgtgagaagcctgaagaaataaaaatggatatcagcaaattaaat
gctcatgaaactttcaggtgcaacttctaa
DBGET
integrated database retrieval system
