KEGG   Homo sapiens (human): 375Help
Entry
375               CDS       T01001                                 

Gene name
ARF1, PVNH8
Definition
(RefSeq) ADP ribosylation factor 1
  KO
K07937  ADP-ribosylation factor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04072  Phospholipase D signaling pathway
hsa04144  Endocytosis
hsa05110  Vibrio cholerae infection
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05134  Legionellosis
Network
nt06134  CGAS-STING signaling (viruses and bacteria)
  Element
N00946  Shigella IpaJ to cGAS-STING signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    375 (ARF1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    375 (ARF1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    375 (ARF1)
   05130 Pathogenic Escherichia coli infection
    375 (ARF1)
   05132 Salmonella infection
    375 (ARF1)
   05131 Shigellosis
    375 (ARF1)
   05134 Legionellosis
    375 (ARF1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    375 (ARF1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    375 (ARF1)
   04031 GTP-binding proteins [BR:hsa04031]
    375 (ARF1)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Lipid raft mediated endocytosis
   GRAF1-dependent endocytosis
    375 (ARF1)
  Arf GTPases and associated proteins
   Arf GTPases
    375 (ARF1)
 Endosome - Golgi transport
    375 (ARF1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   375 (ARF1)
GTP-binding proteins [BR:hsa04031]
 Small (monomeric) G-proteins
  Arf/Sar Family
   Arf [OT]
    375 (ARF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Arf SRPRB Roc Ras G-alpha Gtr1_RagA MMR_HSR1 6PF2K
Motif
Other DBs
NCBI-GeneID: 375
NCBI-ProteinID: NP_001019397
OMIM: 103180
HGNC: 652
Ensembl: ENSG00000143761
Vega: OTTHUMG00000037595
Pharos: P84077(Tchem)
UniProt: P84077 A0A024R3Q0
LinkDB All DBs
Structure
PDB: 

Position
1q42.13
AA seq 181 aa AA seqDB search
MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN
ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV
LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ
K
NT seq 546 nt NT seq  +upstreamnt  +downstreamnt
atggggaacatcttcgccaacctcttcaagggcctttttggcaaaaaagaaatgcgcatc
ctcatggtgggcctggatgctgcagggaagaccacgatcctctacaagcttaagctgggt
gagatcgtgaccaccattcccaccataggcttcaacgtggaaaccgtggagtacaagaac
atcagcttcactgtgtgggacgtgggtggccaggacaagatccggcccctgtggcgccac
tacttccagaacacacaaggcctgatcttcgtggtggacagcaatgacagagagcgtgtg
aacgaggcccgtgaggagctcatgaggatgctggccgaggacgagctccgggatgctgtc
ctcctggtgttcgccaacaagcaggacctccccaacgccatgaatgcggccgagatcaca
gacaagctggggctgcactcactacgccacaggaactggtacattcaggccacctgcgcc
accagcggcgacgggctctatgaaggactggactggctgtccaatcagctccggaaccag
aagtga

KEGG   Homo sapiens (human): 382Help
Entry
382               CDS       T01001                                 

Gene name
ARF6
Definition
(RefSeq) ADP ribosylation factor 6
  KO
K07941  ADP-ribosylation factor 6
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04072  Phospholipase D signaling pathway
hsa04144  Endocytosis
hsa04666  Fc gamma R-mediated phagocytosis
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    382 (ARF6)
   04072 Phospholipase D signaling pathway
    382 (ARF6)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    382 (ARF6)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    382 (ARF6)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    382 (ARF6)
   05132 Salmonella infection
    382 (ARF6)
   05135 Yersinia infection
    382 (ARF6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    382 (ARF6)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    382 (ARF6)
   04031 GTP-binding proteins [BR:hsa04031]
    382 (ARF6)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    382 (ARF6)
  Arf GTPases and associated proteins
   Arf GTPases
    382 (ARF6)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   382 (ARF6)
  Exosomal proteins of colorectal cancer cells
   382 (ARF6)
GTP-binding proteins [BR:hsa04031]
 Small (monomeric) G-proteins
  Arf/Sar Family
   Arf [OT]
    382 (ARF6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Arf Roc Ras SRPRB G-alpha Gtr1_RagA MMR_HSR1 6PF2K SpoOE-like CRISPR_Cas2
Motif
Other DBs
NCBI-GeneID: 382
NCBI-ProteinID: NP_001654
OMIM: 600464
HGNC: 659
Ensembl: ENSG00000165527
Vega: OTTHUMG00000140296
Pharos: P62330(Tbio)
UniProt: P62330
LinkDB All DBs
Structure
PDB: 

Position
14q21.3
AA seq 175 aa AA seqDB search
MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFN
VWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIF
ANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS
NT seq 528 nt NT seq  +upstreamnt  +downstreamnt
atggggaaggtgctatccaaaatcttcgggaacaaggaaatgcggatcctcatgttgggc
ctggacgcggccggcaagacaacaatcctgtacaagttgaagctgggccagtcggtgacc
accattcccactgtgggtttcaacgtggagacggtgacttacaaaaatgtcaagttcaac
gtatgggatgtgggcggccaggacaagatccggccgctctggcggcattactacactggg
acccaaggtctcatcttcgtagtggactgcgccgaccgcgaccgcatcgatgaggctcgc
caggagctgcaccgcattatcaatgaccgggagatgagggacgccataatcctcatcttc
gccaacaagcaggacctgcccgatgccatgaaaccccacgagatccaggagaaactgggc
ctgacccggattcgggacaggaactggtatgtgcagccctcctgtgccacctcaggggac
ggactctatgaggggctcacatggttaacctctaactacaaatcttaa

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