Homo sapiens (human): 3768
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Entry
3768 CDS
T01001
Symbol
KCNJ12, IRK-2, IRK2, KCNJN1, Kir2.2, hIRK, hIRK1, hkir2.2x, kcnj12x
Name
(RefSeq) potassium inwardly rectifying channel subfamily J member 12
KO
K05005
potassium inwardly-rectifying channel subfamily J member 12/18
Organism
hsa
Homo sapiens (human)
Pathway
hsa04725
Cholinergic synapse
hsa04921
Oxytocin signaling pathway
Drug target
Amiodarone (
DG00204
):
D00636
<JP/US>
D02910
Bepridil (
DG00333
):
D00631
<JP>
D07520
Nifekalant hydrochloride:
D01856
<JP>
Terikalant:
D09757
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04921 Oxytocin signaling pathway
3768 (KCNJ12)
09156 Nervous system
04725 Cholinergic synapse
3768 (KCNJ12)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
3768 (KCNJ12)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Potassium channel, inwardly-rectifying (Kir)
3768 (KCNJ12)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
IRK_C
IRK
IRK_N
Ion_trans_2
DUF92
Motif
Other DBs
NCBI-GeneID:
3768
NCBI-ProteinID:
NP_066292
OMIM:
602323
HGNC:
6258
Ensembl:
ENSG00000184185
Pharos:
Q14500
(Tbio)
UniProt:
Q14500
LinkDB
All DBs
Position
17:21376357..21419870
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AA seq
433 aa
AA seq
DB search
MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
VLEQRPYRRESEI
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcggccagccgggccaacccctacagcatcgtgtcatcggaggaggacgggctg
cacctggtcaccatgtcgggcgccaacggcttcggcaacggcaaggtgcacacgcggcgc
aggtgccgcaaccgcttcgtcaagaagaatggccagtgcaacattgagttcgccaacatg
gacgagaagtcacagcgctacctggctgacatgttcaccacctgtgtggacatccgctgg
cggtacatgctgctcatcttctcgctggccttccttgcctcctggctgctgttcggcatc
atcttctgggtcatcgcggtggcacacggtgacctggagccggctgagggccggggccgc
acaccctgtgtgatgcaggtgcacggcttcatggcggccttcctcttctccatcgagacg
cagaccaccatcggctacgggctgcgctgtgtgacggaggagtgcccggtggccgtcttc
atggtggtggcccagtccatcgtgggctgcatcatcgactccttcatgattggtgccatc
atggccaagatggcaaggcccaagaagcgggcacagacgctgctgttcagccacaacgcc
gtggtggccctgcgtgacggcaagctctgcctcatgtggcgtgtgggtaacctgcgcaag
agccacattgtggaggcccatgtgcgcgcgcagctcatcaagccgcgggtcaccgaggag
ggcgagtacatcccgctggaccagatcgacatcgatgtgggcttcgacaagggcctggac
cgcatctttctggtgtcgcccatcaccatcttgcatgagattgacgaggccagcccgctc
ttcggcatcagccggcaggacctggagacggacgactttgagatcgtggtcatcctggaa
ggcatggtggaggccacagccatgaccacccaggcccgcagctcctacctggccaatgag
atcctgtggggtcaccgctttgagcccgtgctcttcgaggagaagaaccagtacaagatt
gactactcgcacttccacaagacctatgaggtgccctctacgccccgctgcagtgcgaag
gatctggtagagaacaagttcctgctgcccagcgccaactccttctgctacgagaacgag
ctggccttcctgagccgtgacgaggaggatgaggcggacggagaccaggacggccgaagc
cgggacggcctcagcccccaggccaggcatgactttgacagactccaggctggcggcggg
gtcctggagcagcggccctacagacgggagtcagagatctga
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