KEGG   Homo sapiens (human): 387332
Entry
387332            CDS       T01001                                 

Gene name
TBPL2, TBP2, TRF3
Definition
(RefSeq) TATA-box binding protein like 2
  KO
K03120  transcription initiation factor TFIID TATA-box-binding protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa03022  Basal transcription factors
hsa05016  Huntington disease
hsa05017  Spinocerebellar ataxia
hsa05165  Human papillomavirus infection
hsa05166  Human T-cell leukemia virus 1 infection
hsa05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03022 Basal transcription factors
    387332 (TBPL2)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    387332 (TBPL2)
  09164 Neurodegenerative disease
   05016 Huntington disease
    387332 (TBPL2)
   05017 Spinocerebellar ataxia
    387332 (TBPL2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    387332 (TBPL2)
   05165 Human papillomavirus infection
    387332 (TBPL2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    387332 (TBPL2)
   03021 Transcription machinery [BR:hsa03021]
    387332 (TBPL2)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   TATA-binding proteins
    387332 (TBPL2)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Basal transcription factors
    TFIID
     387332 (TBPL2)
  RNA polymerase III system
    TFIIIB
     387332 (TBPL2)
  RNA polymerase I system
    SL1/TIF-1B
     387332 (TBPL2)
SSDB
Motif
Pfam: TBP DUF3378
Other DBs
NCBI-GeneID: 387332
NCBI-ProteinID: NP_950248
OMIM: 608964
HGNC: 19841
Ensembl: ENSG00000182521
Vega: OTTHUMG00000140313
Pharos: Q6SJ96(Tbio)
UniProt: Q6SJ96
LinkDB
Position
14q22.3
AA seq 375 aa
MASAPWPERVPRLLAPRLPSYPPPPPTVGLRSMEQEETYLELYLDQCAAQDGLAPPRSPL
FSPVVPYDMYILNASNPDTAFNSNPEVKETSGDFSSVDLSFLPDEVTQENKDQPVISKHE
TEENSESQSPQSRLPSPSEQDVGLGLNSSSLSNSHSQLHPGDTDSVQPSPEKPNSDSLSL
ASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMR
IREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCD
VRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYE
AFENIYPILKGFKKA
NT seq 1128 nt   +upstreamnt  +downstreamnt
atggcctctgcgccctggccggagcgggttccgaggctgctcgctccgcgcttaccctct
tacccgcccccacccccaacagtgggattacggtccatggagcaggaggagacctacctg
gagctctacctggaccagtgcgccgctcaggatggccttgccccacccaggtctcccctg
ttcagcccagttgtaccttatgatatgtacatactgaatgcatccaatccggatactgca
tttaattcgaaccctgaagtcaaagaaacatctggtgatttctcatctgtggatcttagc
ttcctaccagatgaagttacccaggaaaataaagaccagcctgtcattagcaaacacgaa
actgaagaaaattctgaaagccaaagtccacaaagtaggttgccatcacccagcgaacag
gacgttgggctgggcttaaacagcagcagtttgtcaaattcccattcacagctgcaccct
ggtgatactgactcagtccagccctctcctgagaaaccaaactccgactccttgtctctg
gcatccataactcccatgacaccaatgacccctatttcagaatgttgtggaattgtacct
caactacagaatatagtttccactgtaaacctggcctgtaagttggatctgaagaaaata
gctttgcatgcaaaaaatgcagaatataacccaaagaggtttgctgctgtcataatgagg
atccgagagcccaggacaacagcccttatatttagctctgggaagatggtctgcacggga
gccaaaagtgaagagcagtctcgacttgcagcaagaaaatatgctcgtgtggtgcagaag
cttgggttccctgccagattcctcgattttaaaattcagaacatggttggaagctgtgat
gtgagatttcccatcaggctggaaggtttggtgctaacccatcagcagttcagtagttac
gagcctgaactgtttcctggtcttatttatagaatggtaaaaccacgaattgtgttgctt
atctttgtatctggaaaagttgtgttgacaggtgccaaagaacgttctgagatctatgaa
gcatttgaaaacatctatcctattctaaaaggttttaaaaaagcctga

KEGG   Homo sapiens (human): 6908
Entry
6908              CDS       T01001                                 

Gene name
TBP, GTF2D, GTF2D1, HDL4, SCA17, TFIID
Definition
(RefSeq) TATA-box binding protein
  KO
K03120  transcription initiation factor TFIID TATA-box-binding protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa03022  Basal transcription factors
hsa05016  Huntington disease
hsa05017  Spinocerebellar ataxia
hsa05165  Human papillomavirus infection
hsa05166  Human T-cell leukemia virus 1 infection
hsa05203  Viral carcinogenesis
Network
nt06140  Transcription (viruses)
nt06166  Human papillomavirus (HPV)
  Element
N00376  HPV E7 to TBP1-mediated transcription
Disease
H00063  Spinocerebellar ataxia (SCA)
H01243  Huntington disease-like syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03022 Basal transcription factors
    6908 (TBP)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    6908 (TBP)
  09164 Neurodegenerative disease
   05016 Huntington disease
    6908 (TBP)
   05017 Spinocerebellar ataxia
    6908 (TBP)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    6908 (TBP)
   05165 Human papillomavirus infection
    6908 (TBP)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    6908 (TBP)
   03021 Transcription machinery [BR:hsa03021]
    6908 (TBP)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   TATA-binding proteins
    6908 (TBP)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Basal transcription factors
    TFIID
     6908 (TBP)
  RNA polymerase III system
    TFIIIB
     6908 (TBP)
  RNA polymerase I system
    SL1/TIF-1B
     6908 (TBP)
SSDB
Motif
Pfam: TBP EPL1 DDHD Presenilin UPF0565 ABC2_membrane_2 DUF4746 TMEM51 TFIIA SpoIIP BAF1_ABF1 MMR1 Cellulose_synt Otopetrin PAT1 Tim54 FemAB DUF3295 DUF1501 TraV VIT1 DUF4228 Ndc1_Nup
Other DBs
NCBI-GeneID: 6908
NCBI-ProteinID: NP_003185
OMIM: 600075
HGNC: 11588
Ensembl: ENSG00000112592
Vega: OTTHUMG00000016084
Pharos: P20226(Tbio)
UniProt: P20226 Q32MN7
LinkDB
Structure
PDB: 

Position
6q27
AA seq 339 aa
MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQ
QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ
LFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDL
KTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARV
VQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRI
VLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT
NT seq 1020 nt   +upstreamnt  +downstreamnt
atggatcagaacaacagcctgccaccttacgctcagggcttggcctcccctcagggtgcc
atgactcccggaatccctatctttagtccaatgatgccttatggcactggactgacccca
cagcctattcagaacaccaatagtctgtctattttggaagagcaacaaaggcagcagcag
caacaacaacagcagcagcagcagcagcagcagcaacagcaacagcagcagcagcagcag
cagcagcagcagcagcagcagcagcagcagcagcagcagcaacaggcagtggcagctgca
gccgttcagcagtcaacgtcccagcaggcaacacagggaacctcaggccaggcaccacag
ctcttccactcacagactctcacaactgcacccttgccgggcaccactccactgtatccc
tcccccatgactcccatgacccccatcactcctgccacgccagcttcggagagttctggg
attgtaccgcagctgcaaaatattgtatccacagtgaatcttggttgtaaacttgaccta
aagaccattgcacttcgtgcccgaaacgccgaatataatcccaagcggtttgctgcggta
atcatgaggataagagagccacgaaccacggcactgattttcagttctgggaaaatggtg
tgcacaggagccaagagtgaagaacagtccagactggcagcaagaaaatatgctagagtt
gtacagaagttgggttttccagctaagttcttggacttcaagattcagaatatggtgggg
agctgtgatgtgaagtttcctataaggttagaaggccttgtgctcacccaccaacaattt
agtagttatgagccagagttatttcctggtttaatctacagaatgatcaaacccagaatt
gttctccttatttttgtttctggaaaagttgtattaacaggtgctaaagtcagagcagaa
atttatgaagcatttgaaaacatctaccctattctaaagggattcaggaagacgacgtaa

KEGG   Homo sapiens (human): 9519
Entry
9519              CDS       T01001                                 

Gene name
TBPL1, MGC:8389, MGC:9620, STUD, TLF, TLP, TRF2
Definition
(RefSeq) TATA-box binding protein like 1
  KO
K03120  transcription initiation factor TFIID TATA-box-binding protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa03022  Basal transcription factors
hsa05016  Huntington disease
hsa05017  Spinocerebellar ataxia
hsa05165  Human papillomavirus infection
hsa05166  Human T-cell leukemia virus 1 infection
hsa05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03022 Basal transcription factors
    9519 (TBPL1)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    9519 (TBPL1)
  09164 Neurodegenerative disease
   05016 Huntington disease
    9519 (TBPL1)
   05017 Spinocerebellar ataxia
    9519 (TBPL1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    9519 (TBPL1)
   05165 Human papillomavirus infection
    9519 (TBPL1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    9519 (TBPL1)
   03021 Transcription machinery [BR:hsa03021]
    9519 (TBPL1)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   TATA-binding proteins
    9519 (TBPL1)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Basal transcription factors
    TFIID
     9519 (TBPL1)
  RNA polymerase III system
    TFIIIB
     9519 (TBPL1)
  RNA polymerase I system
    SL1/TIF-1B
     9519 (TBPL1)
SSDB
Motif
Pfam: TBP DUF3378
Other DBs
NCBI-GeneID: 9519
NCBI-ProteinID: NP_001240605
OMIM: 605521
HGNC: 11589
Ensembl: ENSG00000028839
Vega: OTTHUMG00000015609
Pharos: P62380(Tbio)
UniProt: P62380
LinkDB
Position
6q23.2
AA seq 186 aa
MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATI
WSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEF
TKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFE
SRKEIL
NT seq 561 nt   +upstreamnt  +downstreamnt
atggatgcagacagtgatgttgcattggacattctaattacaaatgtagtctgtgttttt
agaacaagatgtcatttaaacttaaggaagattgctttggaaggagcaaatgtaatttat
aaacgtgatgttggaaaagtattaatgaagcttagaaaacctagaattacagctacaatt
tggtcctcaggaaaaattatttgcactggagcaacaagtgaagaagaagctaaatttggt
gccagacgcttagcccgtagtctgcagaaactaggttttcaggtaatatttacagatttt
aaggttgttaacgttctggcagtgtgtaacatgccatttgaaatccgtttgccagaattc
acaaagaacaatagacctcatgccagttacgaacctgaacttcatcctgctgtgtgctat
cggataaaatctctaagagctacattacagattttttcaacaggaagtatcacagtaaca
gggcccaatgtaaaggctgttgctactgctgtggaacagatttacccatttgtgtttgaa
agcaggaaagaaattttataa

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