KEGG   Homo sapiens (human): 3955Help
Entry
3955              CDS       T01001                                 

Gene name
LFNG, SCDO3
Definition
(RefSeq) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  KO
K05948  fringe [EC:2.4.1.222]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00514  Other types of O-glycan biosynthesis
hsa04330  Notch signaling pathway
hsa05165  Human papillomavirus infection
Disease
H00517  Spondylocostal dysostosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00514 Other types of O-glycan biosynthesis
    3955 (LFNG)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    3955 (LFNG)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3955 (LFNG)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    3955 (LFNG)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.222  O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
     3955 (LFNG)
Glycosyltransferases [BR:hsa01003]
 Glycan extension
  O-Glycan
   3955 (LFNG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Fringe Galactosyl_T Fur_reg_FbpA
Motif
Other DBs
NCBI-GeneID: 3955
NCBI-ProteinID: NP_001035257
OMIM: 602576
HGNC: 6560
Ensembl: ENSG00000106003
Vega: OTTHUMG00000152043
Pharos: Q8NES3(Tbio)
UniProt: Q8NES3
LinkDB All DBs
Position
7p22.3
AA seq 379 aa AA seqDB search
MLKRCGRRLLLALAGALLACLLVLTADPPPPPLPAERGRRALRSLAGPAGAAPAPGLGAA
AAAPGALVRDVHSLSEYFSLLTRARRDAGPPPGAAPRPADGHPRPLAEPLAPRDVFIAVK
TTKKFHRARLDLLLETWISRHKEMTFIFTDGEDEALARHTGNVVITNCSAAHSRQALSCK
MAVEYDRFIESGRKWFCHVDDDNYVNLRALLRLLASYPHTRDVYVGKPSLDRPIQAMERV
SENKVRPVHFWFATGGAGFCISRGLALKMSPWASGGHFMNTAERIRLPDDCTIGYIVEAL
LGVPLIRSGLFHSHLENLQQVPTSELHEQVTLSYGMFENKRNAVHVKGPFSVEADPSRFR
SIHCHLYPDTPWCPRTAIF
NT seq 1140 nt NT seq  +upstreamnt  +downstreamnt
atgctcaagcgctgcggccggcgcctgctgctggcgctggcgggcgcgctgctcgcctgc
ctgctggtgctcaccgccgacccgccgccgcctccactgcccgccgagcgcggccggcgc
gcgctgcgcagcctggcgggccccgcgggggctgccccggcgcccgggctgggggcggcg
gcggcggcgcccggggcgctggtccgcgacgtgcacagtctgtccgagtacttcagcctg
ctcacccgcgcgcgcagagatgcgggcccgccgcccggggctgccccccgccccgccgac
ggccacccgcgccccctggccgagccgctcgcgccccgagacgtcttcatcgctgtcaag
accaccaaaaagttccaccgcgcgcgcctcgacctgctgctggagacctggatctcgcgc
cacaaggagatgacgttcatcttcactgacggggaagatgaggccctggccaggcacacg
ggcaacgtggtcatcacaaactgctcggccgcccacagccgccaggcgctgtcctgcaag
atggccgtggagtatgaccgcttcatcgagtccggcaggaagtggttctgccacgtggac
gatgacaactacgtcaacctgcgggccctgctgcggctgctggccagctacccgcacacg
cgggacgtctacgtcggcaagcccagcctggacaggcccatccaggccatggagcgggtc
agcgagaacaaggtgcgtcctgtccacttctggtttgccacgggcggcgctggcttctgc
atcagccgtgggctggctctgaagatgagcccgtgggccagcgggggtcacttcatgaat
acggctgagcggatccggctgcctgatgactgcaccatcggctacatcgtggaggccctg
ctgggtgtgcccctcatccgcagcggcctcttccactcccacctggagaacctgcagcag
gtgcccacctcggagctccacgagcaggtgacgctgagctacggtatgtttgaaaacaag
cggaacgccgtccacgtgaaggggcccttctcggtggaggccgacccatccaggttccgc
tccatccactgccacctgtacccggacacaccctggtgtccccgcactgccatcttctag

KEGG   Homo sapiens (human): 4242Help
Entry
4242              CDS       T01001                                 

Gene name
MFNG
Definition
(RefSeq) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  KO
K05948  fringe [EC:2.4.1.222]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00514  Other types of O-glycan biosynthesis
hsa04330  Notch signaling pathway
hsa05165  Human papillomavirus infection
Network
nt06116  NOTCH signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00381  HPV E6 to Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00514 Other types of O-glycan biosynthesis
    4242 (MFNG)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    4242 (MFNG)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    4242 (MFNG)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    4242 (MFNG)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.222  O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
     4242 (MFNG)
Glycosyltransferases [BR:hsa01003]
 Glycan extension
  O-Glycan
   4242 (MFNG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Fringe Galactosyl_T
Motif
Other DBs
NCBI-GeneID: 4242
NCBI-ProteinID: NP_002396
OMIM: 602577
HGNC: 7038
Ensembl: ENSG00000100060
Vega: OTTHUMG00000150560
Pharos: O00587(Tbio)
UniProt: O00587
LinkDB All DBs
Position
22q13.1
AA seq 321 aa AA seqDB search
MQCRLPRGLAGALLTLLCMGLLCLRYHLNLSPQRVQGTPELSQPNPGPPKLQLHDVFIAV
KTTRAFHRLRLELLLDTWVSRTREQTFVFTDSPDKGLQERLGSHLVVTNCSAEHSHPALS
CKMAAEFDTFLASGLRWFCHVDDDNYVNPRALLQLLRAFPLARDVYVGRPSLNRPIHASE
PQPHNRTRLVQFWFATGGAGFCINRKLALKMAPWASGSRFMDTSALIRLPDDCTMGYIIE
CKLGGRLQPSPLFHSHLETLQLLRTAQLPEQVTLSYGVFEGKLNVIKLQGPFSPEEDPSR
FRSLHCLLYPDTPWCPQLGAR
NT seq 966 nt NT seq  +upstreamnt  +downstreamnt
atgcagtgccggctcccgcggggcctggctggagccctcctcaccctcctgtgcatgggg
ctcctgtgtctgcggtaccacttgaacctgtccccgcagcgggtacaagggacccccgag
ctgagccagccgaacccggggccccctaagctacagctacacgatgtcttcattgcagtg
aagacgacccgggctttccaccgcttgcgcctggagctgctgcttgacacgtgggtttcc
aggaccagggaacagacatttgtcttcaccgacagcccagacaaaggcctccaggagaga
ctggggtcccaccttgtggtcaccaactgctccgcggaacacagccacccagctctgtcc
tgcaagatggctgctgagttcgacaccttcttggccagtgggcttaggtggttctgccat
gtggacgatgacaactatgtgaacccaagggcgctgctgcagcttctgagagccttcccg
ctggcccgcgacgtctatgtgggaaggcccagcctgaaccggcccatccatgcctcagag
ccacagccccacaaccgcacgaggctggtacagttctggtttgccactgggggtgctggc
ttctgcatcaatcgcaaactggctttgaagatggctccgtgggccagtggctcccgtttc
atggacacatctgctctcatccggctgcctgatgactgcaccatgggctatatcattgag
tgcaagctgggcggccgcctgcagcccagccccctctttcactcccacctggagaccctg
cagctgctgaggactgcacagctcccagaacaggtcaccctcagctacggtgtctttgag
gggaaactcaacgtcattaagctacagggccccttctccccggaggaggacccctccaga
tttcgctccctccattgtctgctctatccagatacaccctggtgtccccagctgggtgcc
cgatga

KEGG   Homo sapiens (human): 5986Help
Entry
5986              CDS       T01001                                 

Gene name
RFNG
Definition
(RefSeq) RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  KO
K05948  fringe [EC:2.4.1.222]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00514  Other types of O-glycan biosynthesis
hsa04330  Notch signaling pathway
hsa05165  Human papillomavirus infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00514 Other types of O-glycan biosynthesis
    5986 (RFNG)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    5986 (RFNG)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    5986 (RFNG)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    5986 (RFNG)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.222  O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
     5986 (RFNG)
Glycosyltransferases [BR:hsa01003]
 Glycan extension
  O-Glycan
   5986 (RFNG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Fringe
Motif
Other DBs
NCBI-GeneID: 5986
NCBI-ProteinID: NP_002908
OMIM: 602578
HGNC: 9974
Ensembl: ENSG00000169733
Vega: OTTHUMG00000178512
Pharos: Q9Y644(Tdark)
UniProt: Q9Y644 Q8N9R1
LinkDB All DBs
Position
17q25.3
AA seq 331 aa AA seqDB search
MSRARGALCRACLALAAALAALLLLPLPLPRAPAPARTPAPAPRAPPSRPAAPSLRPDDV
FIAVKTTRKNHGPRLRLLLRTWISRARQQTFIFTDGDDPELELQGGDRVINTNCSAVRTR
QALCCKMSVEYDKFIESGRKWFCHVDDDNYVNARSLLHLLSSFSPSQDVYLGRPSLDHPI
EATERVQGGRTVTTVKFWFATGGAGFCLSRGLALKMSPWASLGSFMSTAEQVRLPDDCTV
GYIVEGLLGARLLHSPLFHSHLENLQRLPPDTLLQQVTLSHGGPENPHNVVNVAGGFSLH
QDPTRFKSIHCLLYPDTDWCPRQKQGAPTSR
NT seq 996 nt NT seq  +upstreamnt  +downstreamnt
atgagccgcgcgcgtggggcgctgtgccgggcctgcctcgcgctggccgcggccctggcc
gcgctgctgttactgccgctgccgctgccccgcgcgcccgccccggcccggacccccgcc
ccggccccgcgcgcgcccccgtcccggcccgctgcccccagcctgcggcctgacgacgtc
ttcatcgccgtcaagaccacccggaagaaccacgggccgcgcctgcggctgctgctgcgc
acctggatctcccgggcccgccagcagacgtttatcttcaccgacggggacgaccctgag
ctcgagctccagggcggcgaccgtgtcatcaacaccaactgctcggcggtgcgcactcgt
caggccctctgctgcaagatgtccgtggagtatgacaagttcattgagtccgggcgcaag
tggttttgccacgtggatgatgacaattatgtgaacgccaggagcctcctgcacctgctc
tccagcttctcacccagccaggacgtctacctggggcggcccagcctggaccaccccatt
gaggccaccgagagggtccagggtggcagaactgtgaccacggtcaagttctggtttgct
actggtggggccgggttctgcctcagcagaggccttgccctcaagatgagcccatgggcc
agcctgggcagcttcatgagcacagctgagcaggtgcggctgccggatgactgcacagtt
ggctacatcgtggaggggctcctgggcgcccgcctgctgcacagccccctcttccactct
cacctggagaacctgcagaggctgccgcccgacaccctgctccagcaggttaccttgagc
catgggggtcctgagaacccacataacgtggtgaacgtggctggaggcttcagcctgcat
caagaccccacacggtttaagtctatccattgtcttctgtacccagacacggactggtgt
cccaggcagaaacagggcgccccgacctctcggtga

DBGET integrated database retrieval system