Homo sapiens (human): 4629 Entry 4629              CDS       T01001                                  Gene name MYH11, AAT4, FAA4, SMHC, SMMHC Definition (RefSeq) myosin heavy chain 11   KO K10352   myosin heavy chain Organism hsa  Homo sapiens (human) Pathway hsa04270   Vascular smooth muscle contraction hsa04530   Tight junction hsa05130   Pathogenic Escherichia coli infection hsa05132   Salmonella infection Disease H00801   Familial thoracic aortic aneurysm and dissection H01630   Patent ductus arteriosus Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09144 Cellular community - eukaryotes    04530 Tight junction     4629 (MYH11)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     4629 (MYH11)  09160 Human Diseases   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     4629 (MYH11)    05132 Salmonella infection     4629 (MYH11)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:hsa04812]     4629 (MYH11)    04147 Exosome [BR:hsa04147]     4629 (MYH11) Cytoskeleton proteins [BR:hsa04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Myosins      4629 (MYH11) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of bladder cancer cells    4629 (MYH11) SSDB Motif Pfam:  Myosin_tail_1 Myosin_head Myosin_N CC2-LZ IQ ADIP AAA_22 Other DBs NCBI-GeneID:  4629 NCBI-ProteinID:  NP_002465 OMIM:  160745 HGNC:  7569 Ensembl:  ENSG00000133392 Vega:  OTTHUMG00000129935 Pharos:  P35749(Tbio) UniProt:  P35749 A0A024QZJ4 LinkDB Position 16p13.11 AA seq 1972 aa MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE VNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDADFNGTKASE NT seq 5919 nt   +upstreamnt  +downstreamnt atggcgcagaagggccaactcagtgacgatgagaagttcctctttgtggacaaaaacttc atcaacagcccagtggcccaggctgactgggccgccaagagactcgtctgggtcccctcg gagaagcagggcttcgaggcagccagcattaaggaggagaagggggatgaggtggttgtg gagctggtggagaatggcaagaaggtcacggttgggaaagatgacatccagaagatgaac ccacccaagttctccaaggtggaggacatggcggagctgacgtgcctcaacgaagcctcc gtgctacacaacctgagggagcggtacttctcagggctaatatatacgtactctggcctc ttctgcgtggtggtcaacccctataaacacctgcccatctactcggagaagatcgtcgac atgtacaagggcaagaagaggcacgagatgccgcctcacatctacgccatcgcagacacg gcctaccggagcatgcttcaagatcgggaggaccagtccattctatgcacaggcgagtct ggagccgggaaaaccgaaaacaccaagaaggtcattcagtacctggccgtggtggcctcc tcccacaagggcaagaaagacacaagtatcacgggagagctggaaaagcagcttctacaa gcaaacccgattctggaggctttcggcaacgccaaaacagtgaagaacgacaactcctca cgattcggcaaattcatccgcatcaacttcgacgtcacgggttacatcgtgggagccaac attgagacctatctgctagaaaaatcacgggcaattcgccaagccagagacgagaggaca ttccacatcttttactacatgattgctggagccaaggagaagatgagaagtgacttgctt ttggagggcttcaacaactacaccttcctctccaatggctttgtgcccatcccagcagcc caggatgatgagatgttccaggaaaccgtggaggccatggcaatcatgggtttcagcgag gaggagcagctatccatattgaaggtggtatcatcggtcctgcagcttggaaatatcgtc ttcaagaaggaaagaaacacagaccaggcgtccatgccagataacacagctgctcagaaa gtttgccacctcatgggaattaatgtgacagatttcaccagatccatcctcactcctcgt atcaaggttgggcgagatgtggtacagaaagctcagacaaaagaacaggctgactttgct gtagaggctttggccaaggcaacatatgagcgccttttccgctggatactcacccgcgtg aacaaagccctggacaagacccatcggcaaggggcttccttcctggggatcctggatata gctggatttgagatctttgaggtgaactccttcgagcagctgtgcatcaactacaccaac gagaagctgcagcagctcttcaaccacaccatgttcatcctggagcaggaggagtaccag cgcgagggcatcgagtggaacttcatcgactttgggctggacctacagccctgcatcgag ctcatcgagcgaccgaacaaccctccaggtgtgctggccctgctggacgaggaatgctgg ttccccaaagccacggacaagtctttcgtggagaagctgtgcacggagcagggcagccac cccaagttccagaagcccaagcagctcaaggacaagactgagttctccatcatccattat gctgggaaggtggactataatgcgagtgcctggctgaccaagaatatggacccgctgaat gacaacgtgacttccctgctcaatgcctcctccgacaagtttgtggccgacctgtggaag gacgtggaccgcatcgtgggcctggaccagatggccaagatgacggagagctcgctgccc agcgcctccaagaccaagaagggcatgttccgcacagtggggcagctgtacaaggagcag ctgggcaagctgatgaccacgctacgcaacaccacgcccaacttcgtgcgctgcatcatc cccaaccacgagaagaggtccggcaagctggatgcgttcctggtgctggagcagctgcgg tgcaatggggtgctggaaggcattcgcatctgccggcagggcttccccaaccggatcgtc ttccaggagttccgccaacgctacgagatcctggcggcgaatgccatccccaaaggcttc atggacgggaagcaggcctgcattctcatgatcaaagccctggaacttgaccccaactta tacaggatagggcagagcaaaatcttcttccgaactggcgtcctggcccacctagaggag gagcgagatttgaagatcaccgatgtcatcatggccttccaggcgatgtgtcgtggctac ttggccagaaaggcttttgccaagaggcagcagcagctgaccgccatgaaggtgattcag aggaactgcgccgcctacctcaagctgcggaactggcagtggtggaggcttttcaccaaa gtgaagccactgctgcaggtgacacggcaggaggaggagatgcaggccaaggaggatgaa ctgcagaagaccaaggagcggcagcagaaggcagagaatgagcttaaggagctggaacag aagcactcgcagctgaccgaggagaagaacctgctacaggaacagctgcaggcagagaca gagctgtatgcagaggctgaggagatgcgggtgcggctggcggccaagaagcaggagctg gaggagatactgcatgagatggaggcccgcctggaggaggaggaagacaggggccagcag ctacaggctgaaaggaagaagatggcccagcagatgctggaccttgaagaacagctggag gaggaggaagctgccaggcagaagctgcaacttgagaaggtcacggctgaggccaagatc aagaaactggaggatgagatcctggtcatggatgatcagaacaataaactatcaaaagaa cgaaaactccttgaggagaggattagtgacttaacgacaaatcttgcagaagaggaagaa aaggccaagaatcttaccaagctgaaaaacaagcatgaatctatgatttcagaactggaa gtgcggctaaagaaggaagagaagagccgacaggagctggagaagctgaaacggaagctg gagggtgatgccagcgacttccacgagcagatcgctgacctccaggcgcagatcgcagag ctcaagatgcagctggccaagaaggaggaggagctgcaggcggccctggccaggcttgac gatgaaatcgctcagaagaacaatgccctgaagaagatccgggagctggagggccacatc tcagacctccaggaggacctggactcagagcgggccgccaggaacaaggctgaaaagcag aagcgagacctcggcgaggagctggaggccctaaagacagagctggaagacacactggac agcacagccactcagcaggagctcagggccaagagggagcaggaggtgacggtgctgaag aaggccctggatgaagagacgcggtcccatgaggctcaggtccaggagatgaggcagaaa cacgcacaggcggtggaggagctcacagagcagcttgagcagttcaagagggccaaggcg aacctagacaagaataagcagacgctggagaaagagaacgcagacctggccggggagctg cgggtcctgggccaggccaagcaggaggtggaacataagaagaagaagctggaggcgcag gtgcaggagctgcagtccaagtgcagcgatggggagcgggcccgggcggagctcaatgac aaagtccacaagctgcagaatgaagttgagagcgtcacagggatgcttaacgaggccgag gggaaggccattaagctggccaaggacgtggcgtccctcagttcccagctccaggacacc caggagctgcttcaagaagaaacccggcagaagctcaacgtgtctacgaagctgcgccag ctggaggaggagcggaacagcctgcaagaccagctggacgaggagatggaggccaagcag aacctggagcgccacatctccactctcaacatccagctctccgactcgaagaagaagctg caggactttgccagcaccgtggaagctctggaagaggggaagaagaggttccagaaggag atcgagaacctcacccagcagtacgaggagaaggcggccgcttatgataaactggaaaag accaagaacaggcttcagcaggagctggacgacctggttgttgatttggacaaccagcgg caactcgtgtccaacctggaaaagaagcagaggaaatttgatcagttgttagccgaggag aaaaacatctcttccaaatacgcggatgagagggacagagctgaggcagaagccagggag aaggaaaccaaggccctgtccctggctcgggcccttgaagaggccttggaagccaaagag gaactcgagcggaccaacaaaatgctcaaagccgaaatggaagacctggtcagctccaag gatgacgtgggcaagaacgtccatgagctggagaagtccaagcgggccctggagacccag atggaggagatgaagacgcagctggaagagctggaggacgagctgcaagccacggaggac gccaaactgcggctggaagtcaacatgcaggcgctcaagggccagttcgaaagggatctc caagcccgggacgagcagaatgaggagaagaggaggcaactgcagagacagcttcacgag tatgagacggaactggaagacgagcgaaagcaacgtgccctggcagctgcagcaaagaag aagctggaaggggacctgaaagacctggagcttcaggccgactctgccatcaaggggagg gaggaagccatcaagcagctacgcaaactgcaggctcagatgaaggactttcaaagagag ctggaagatgcccgtgcctccagagatgagatctttgccacagccaaagagaatgagaag aaagccaagagcttggaagcagacctcatgcagctacaagaggacctcgccgccgctgag agggctcgcaaacaagcggacctcgagaaggaggaactggcagaggagctggccagtagc ctgtcgggaaggaacgcactccaggacgagaagcgccgcctggaggcccggatcgcccag ctggaggaggagctggaggaggagcagggcaacatggaggccatgagcgaccgggtccgc aaagccacacagcaggccgagcagctcagcaacgagctggccacagagcgcagcacggcc cagaagaatgagagtgcccggcagcagctcgagcggcagaacaaggagctccggagcaag ctccacgagatggagggggccgtcaagtccaagttcaagtccaccatcgcggcgctggag gccaagattgcacagctggaggagcaggtcgagcaggaggccagagagaaacaggcggcc accaagtcgctgaagcagaaagacaagaagctgaaggaaatcttgctgcaggtggaggac gagcgcaagatggccgagcagtacaaggagcaggcagagaaaggcaatgccagggtcaag cagctcaagaggcagctggaggaggcagaggaggagtcccagcgcatcaacgccaaccgc aggaagctgcagcgggagctggatgaggccacggagagcaacgaggccatgggccgcgag gtgaacgcactcaagagcaagctcaggcgaggaaacgagacctctttcgttccttctaga aggtctggaggacgtagagttattgaaaatgcagatggttctgaggaggaaacggacact cgagacgcagacttcaatggaaccaaggccagtgaataa

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