KEGG   Homo sapiens (human): 4772Help
Entry
4772              CDS       T01001                                 

Gene name
NFATC1, NF-ATC, NF-ATc1.2, NFAT2, NFATc
Definition
(RefSeq) nuclear factor of activated T cells 1
  KO
K04446  nuclear factor of activated T-cells, cytoplasmic 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04218  Cellular senescence
hsa04310  Wnt signaling pathway
hsa04380  Osteoclast differentiation
hsa04625  C-type lectin receptor signaling pathway
hsa04650  Natural killer cell mediated cytotoxicity
hsa04658  Th1 and Th2 cell differentiation
hsa04659  Th17 cell differentiation
hsa04660  T cell receptor signaling pathway
hsa04662  B cell receptor signaling pathway
hsa04921  Oxytocin signaling pathway
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa05135  Yersinia infection
hsa05161  Hepatitis B
hsa05163  Human cytomegalovirus infection
hsa05166  Human T-cell leukemia virus 1 infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hsa05321  Inflammatory bowel disease (IBD)
Network
nt06120  Calcium signaling (virus)
nt06124  Chemokine signaling (virus)
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165  Epstein-Barr virus (EBV)
nt06167  Human cytomegalovirus (HCMV)
nt06220  Calcium signaling
  Element
N00147  EGF-EGFR-PLCG-calcineurin signaling pathway
N00172  KSHV K15 to PLCG-calcineurin signaling pathway
N00180  KSHV K1 to PLCG-calcineurin signaling pathway
N00401  CXCR4-GNAQ-PLCB/G-calcineurin signaling pathway
N00402  HCMV US28 to GNAQ-PLCB/G-calcineurin signaling pathway
N00432  HIV gp120 to CXCR4-GNAQ-PLCB/G-calcineurin
N00487  BCR-PLCG-Calcineurin signaling pathway
N00490  HTLV-1 p12 to calcineurin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    4772 (NFATC1)
   04310 Wnt signaling pathway
    4772 (NFATC1)
   04024 cAMP signaling pathway
    4772 (NFATC1)
   04022 cGMP-PKG signaling pathway
    4772 (NFATC1)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    4772 (NFATC1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    4772 (NFATC1)
   04650 Natural killer cell mediated cytotoxicity
    4772 (NFATC1)
   04660 T cell receptor signaling pathway
    4772 (NFATC1)
   04658 Th1 and Th2 cell differentiation
    4772 (NFATC1)
   04659 Th17 cell differentiation
    4772 (NFATC1)
   04662 B cell receptor signaling pathway
    4772 (NFATC1)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    4772 (NFATC1)
  09158 Development
   04380 Osteoclast differentiation
    4772 (NFATC1)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    4772 (NFATC1)
  09163 Immune disease
   05321 Inflammatory bowel disease (IBD)
    4772 (NFATC1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    4772 (NFATC1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    4772 (NFATC1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    4772 (NFATC1)
   05170 Human immunodeficiency virus 1 infection
    4772 (NFATC1)
   05161 Hepatitis B
    4772 (NFATC1)
   05163 Human cytomegalovirus infection
    4772 (NFATC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    4772 (NFATC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    4772 (NFATC1)
Transcription factors [BR:hsa03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) NF-AT
    4772 (NFATC1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: RHD_DNA_bind RHD_dimer TIG
Motif
Other DBs
NCBI-GeneID: 4772
NCBI-ProteinID: NP_001265598
OMIM: 600489
HGNC: 7775
Ensembl: ENSG00000131196
Vega: OTTHUMG00000132897
Pharos: O95644(Tbio)
UniProt: O95644
LinkDB All DBs
Structure
PDB: 

Position
18q23
AA seq 943 aa AA seqDB search
MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQ
GLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGV
ASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVSAPPSSSCPPGLEH
SLCPSSPSPPLPPATQEPTCLQPCSPACPPATGRPQHLPSTVRRDESPTAGPRLLPEVHE
DGSPNLAPIPVTVKREPEELDQLYLDDVNEIIRNDLSSTSTHS
NT seq 2832 nt NT seq  +upstreamnt  +downstreamnt
atgccaagcaccagctttccagtcccttccaagtttccacttggccctgcggctgcggtc
ttcgggagaggagaaactttggggcccgcgccgcgcgccggcggcaccatgaagtcagcg
gaggaagaacactatggctatgcatcctccaacgtcagccccgccctgccgctccccacg
gcgcactccaccctgccggccccgtgccacaaccttcagacctccacaccgggcatcatc
ccgccggcggatcacccctcggggtacggagcagctttggacggtgggcccgcgggctac
ttcctctcctccggccacaccaggcctgatggggcccctgccctggagagtcctcgcatc
gagataacctcgtgcttgggcctgtaccacaacaataaccagtttttccacgatgtggag
gtggaagacgtcctccctagctccaaacggtccccctccacggccacgctgagtctgccc
agcctggaggcctacagagacccctcgtgcctgagcccggccagcagcctgtcctcccgg
agctgcaactcagaggcctcctcctacgagtccaactactcgtacccgtacgcgtccccc
cagacgtcgccatggcagtctccctgcgtgtctcccaagaccacggaccccgaggagggc
tttccccgcgggctgggggcctgcacactgctgggttccccgcggcactccccctccacc
tcgccccgcgccagcgtcactgaggagagctggctgggtgcccgctcctccagacccgcg
tccccttgcaacaagaggaagtacagcctcaacggccggcagccgccctactcaccccac
cactcgcccacgccgtccccgcacggctccccgcgggtcagcgtgaccgacgactcgtgg
ttgggcaacaccacccagtacaccagctcggccatcgtggccgccatcaacgcgctgacc
accgacagcagcctggacctgggagatggcgtccctgtcaagtcccgcaagaccaccctg
gagcagccgccctcagtggcgctcaaggtggagcccgtcggggaggacctgggcagcccc
ccgcccccggccgacttcgcgcccgaagactactcctctttccagcacatcaggaagggc
ggcttctgcgaccagtacctggcggtgccgcagcacccctaccagtgggcgaagcccaag
cccctgtcccctacgtcctacatgagcccgaccctgcccgccctggactggcagctgccg
tcccactcaggcccgtatgagcttcggattgaggtgcagcccaagtcccaccaccgagcc
cactacgagacggagggcagccggggggccgtgaaggcgtcggccggaggacaccccatc
gtgcagctgcatggctacttggagaatgagccgctgatgctgcagcttttcattgggacg
gcggacgaccgcctgctgcgcccgcacgccttctaccaggtgcaccgcatcacagggaag
accgtgtccaccaccagccacgaggccatcctctccaacaccaaagtcctggagatccca
ctcctgccggagaacagcatgcgagccgtcattgactgtgccggaatcctgaaactcaga
aactccgacattgaacttcggaaaggagagacggacatcgggaggaagaacacacgggta
cggctggtgttccgcgttcacgtcccgcaacccagcggccgcacgctgtccctgcaggtg
gcctccaaccccatcgaatgctcccagcgctcagctcaggagctgcctctggtggagaag
cagagcacggacagctatccggtcgtgggcgggaagaagatggtcctgtctggccacaac
ttcctgcaggactccaaggtcattttcgtggagaaagccccagatggccaccatgtctgg
gagatggaagcgaaaactgaccgggacctgtgcaagccgaattctctggtggttgagatc
ccgccatttcggaatcagaggataaccagccccgttcacgtcagtttctacgtctgcaac
gggaagagaaagcgaagccagtaccagcgtttcacctaccttcccgccaacgttccaatt
ataaaaacagaacccactgatgattatgagcctgctccaacctgtggaccggtgagccag
gggttaagtcctctcccaagaccatactacagccagcagctcgcgatgccacccgacccc
agctcctgcctcgtggccggcttcccgccctgtccgcagagaagcaccctgatgccagcg
gcccctggcgtgagccccaagctccacgacctttctcccgctgcctacaccaagggcgtt
gccagcccgggccactgtcacctcggactcccgcagccggccggagaggcccccgccgtc
caggacgtgcccaggccagtggccacgcaccccggctcgcccgggcagccacccccggcc
ctgctgccacagcaggtgagtgcgcctccaagcagtagctgcccccctggtctcgaacac
tcgctctgccccagcagcccctctcctccactcccgcctgccacccaagagccgacctgc
ctgcagccctgcagcccagcgtgcccgcccgccacgggccgcccgcagcacctgccgtcc
acggtccgcagggacgagtctccgactgccgggccacggctgctgccagaggtgcatgag
gacggtagtcctaatttggcccctattcctgtaacggtcaagcgagagcctgaagagttg
gaccagttgtacctggatgacgtaaatgaaataatacgaaatgacctctccagcacgagc
acccactcctag

KEGG   Homo sapiens (human): 4773Help
Entry
4773              CDS       T01001                                 

Gene name
NFATC2, NFAT1, NFATP
Definition
(RefSeq) nuclear factor of activated T cells 2
  KO
K17332  nuclear factor of activated T-cells, cytoplasmic 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04218  Cellular senescence
hsa04310  Wnt signaling pathway
hsa04360  Axon guidance
hsa04370  VEGF signaling pathway
hsa04380  Osteoclast differentiation
hsa04625  C-type lectin receptor signaling pathway
hsa04650  Natural killer cell mediated cytotoxicity
hsa04658  Th1 and Th2 cell differentiation
hsa04659  Th17 cell differentiation
hsa04660  T cell receptor signaling pathway
hsa04662  B cell receptor signaling pathway
hsa04921  Oxytocin signaling pathway
hsa05135  Yersinia infection
hsa05161  Hepatitis B
hsa05163  Human cytomegalovirus infection
hsa05166  Human T-cell leukemia virus 1 infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Network
nt06120  Calcium signaling (virus)
nt06124  Chemokine signaling (virus)
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165  Epstein-Barr virus (EBV)
nt06167  Human cytomegalovirus (HCMV)
nt06220  Calcium signaling
  Element
N00147  EGF-EGFR-PLCG-calcineurin signaling pathway
N00172  KSHV K15 to PLCG-calcineurin signaling pathway
N00180  KSHV K1 to PLCG-calcineurin signaling pathway
N00401  CXCR4-GNAQ-PLCB/G-calcineurin signaling pathway
N00402  HCMV US28 to GNAQ-PLCB/G-calcineurin signaling pathway
N00432  HIV gp120 to CXCR4-GNAQ-PLCB/G-calcineurin
N00487  BCR-PLCG-Calcineurin signaling pathway
N00490  HTLV-1 p12 to calcineurin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    4773 (NFATC2)
   04370 VEGF signaling pathway
    4773 (NFATC2)
   04022 cGMP-PKG signaling pathway
    4773 (NFATC2)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    4773 (NFATC2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    4773 (NFATC2)
   04650 Natural killer cell mediated cytotoxicity
    4773 (NFATC2)
   04660 T cell receptor signaling pathway
    4773 (NFATC2)
   04658 Th1 and Th2 cell differentiation
    4773 (NFATC2)
   04659 Th17 cell differentiation
    4773 (NFATC2)
   04662 B cell receptor signaling pathway
    4773 (NFATC2)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    4773 (NFATC2)
  09158 Development
   04360 Axon guidance
    4773 (NFATC2)
   04380 Osteoclast differentiation
    4773 (NFATC2)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    4773 (NFATC2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    4773 (NFATC2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    4773 (NFATC2)
   05170 Human immunodeficiency virus 1 infection
    4773 (NFATC2)
   05161 Hepatitis B
    4773 (NFATC2)
   05163 Human cytomegalovirus infection
    4773 (NFATC2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    4773 (NFATC2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    4773 (NFATC2)
Transcription factors [BR:hsa03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) NF-AT
    4773 (NFATC2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: RHD_dimer RHD_DNA_bind TIG
Motif
Other DBs
NCBI-GeneID: 4773
NCBI-ProteinID: NP_775114
OMIM: 600490
HGNC: 7776
Ensembl: ENSG00000101096
Vega: OTTHUMG00000032747
Pharos: Q13469(Tbio)
UniProt: Q13469
LinkDB All DBs
Structure
PDB: 

Position
20q13.2
AA seq 925 aa AA seqDB search
MNAPERQPQPDGGDAPGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAY
PDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHE
LIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFIS
DTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPR
PASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGS
AVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGER
RNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHH
RAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRIT
GKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNT
RVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTG
QNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYV
INGKRKRSQPQHFTYHPVPAIKTEPTDEYDPTLICSPTHGGLGSQPYYPQHPMVAESPSC
LVATMAPCQQFRTGLSSPDARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADA
HRSVLVHAGSQGQSSALLHPSPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFAPG
TTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNL
DQTYLDDVNEIIRKEFSGPPARNQT
NT seq 2778 nt NT seq  +upstreamnt  +downstreamnt
atgaacgcccccgagcggcagccccaacccgacggcggggacgccccaggccacgagcct
gggggcagcccccaagacgagcttgacttctccatcctcttcgactatgagtatttgaat
ccgaacgaagaagagccgaatgcacataaggtcgccagcccaccctccggacccgcatac
cccgatgatgtcctggactatggcctcaagccatacagcccccttgctagtctctctggc
gagccccccggccgattcggagagccggatagggtagggccgcagaagtttctgagcgcg
gccaagccagcaggggcctcgggcctgagccctcggatcgagatcactccgtcccacgaa
ctgatccaggcagtggggcccctccgcatgagagacgcgggcctcctggtggagcagccg
cccctggccggggtggccgccagcccgaggttcaccctgcccgtgcccggcttcgagggc
taccgcgagccgctttgcttgagccccgctagcagcggctcctctgccagcttcatttct
gacaccttctccccctacacctcgccctgcgtctcgcccaataacggcgggcccgacgac
ctgtgtccgcagtttcaaaacatccctgctcattattcccccagaacctcgccaataatg
tcacctcgaaccagcctcgccgaggacagctgcctgggccgccactcgcccgtgccccgt
ccggcctcccgctcctcatcgcctggtgccaagcggaggcattcgtgcgccgaggccttg
gttgccctgccgcccggagcctcaccccagcgctcccggagcccctcgccgcagccctca
tctcacgtggcaccccaggaccacggctccccggctgggtacccccctgtggctggctct
gccgtgatcatggatgccctgaacagcctcgccacggactcgccttgtgggatccccccc
aagatgtggaagaccagccctgacccctcgccggtgtctgccgccccatccaaggccggc
ctgcctcgccacatctacccggccgtggagttcctggggccctgcgagcagggcgagagg
agaaactcggctccagaatccatcctgctggttccgcccacttggcccaagccgctggtg
cctgccattcccatctgcagcatcccagtgactgcatccctccctccacttgagtggccg
ctgtccagtcagtcaggctcttacgagctgcggatcgaggtgcagcccaagccacatcac
cgggcccactatgagacagaaggcagccgaggggctgtcaaagctccaactggaggccac
cctgtggttcagctccatggctacatggaaaacaagcctctgggacttcagatcttcatt
gggacagctgatgagcggatccttaagccgcacgccttctaccaggtgcaccgaatcacg
gggaaaactgtcaccaccaccagctatgagaagatagtgggcaacaccaaagtcctggag
atacccttggagcccaaaaacaacatgagggcaaccatcgactgtgcggggatcttgaag
cttagaaacgccgacattgagctgcggaaaggcgagacggacattggaagaaagaacacg
cgggtgagactggttttccgagttcacatcccagagtccagtggcagaatcgtctcttta
cagactgcatctaaccccatcgagtgctcccagcgatctgctcacgagctgcccatggtt
gaaagacaagacacagacagctgcctggtctatggcggccagcaaatgatcctcacgggg
cagaactttacatccgagtccaaagttgtgtttactgagaagaccacagatggacagcaa
atttgggagatggaagccacggtggataaggacaagagccagcccaacatgctttttgtt
gagatccctgaatatcggaacaagcatatccgcacacctgtaaaagtgaacttctacgtc
atcaatgggaagagaaaacgaagtcagcctcagcactttacctaccacccagtcccagcc
atcaagacggagcccacggatgaatatgaccccactctgatctgcagccccacccatgga
ggcctggggagccagccttactacccccagcacccgatggtggccgagtccccctcctgc
ctcgtggccaccatggctccctgccagcagttccgcacggggctctcatcccctgacgcc
cgctaccagcaacagaacccagcggccgtactctaccagcggagcaagagcctgagcccc
agcctgctgggctatcagcagccggccctcatggccgccccgctgtcccttgcggacgct
caccgctctgtgctggtgcacgccggctcccagggccagagctcagccctgctccacccc
tctccgaccaaccagcaggcctcgcctgtgatccactactcacccaccaaccagcagctg
cgctgcggaagccaccaggagttccagcacatcatgtactgcgagaatttcgcaccaggc
accaccagacctggcccgcccccggtcagtcaaggtcagaggctgagcccgggttcctac
cccacagtcattcagcagcagaatgccacgagccaaagagccgccaaaaacggacccccg
gtcagtgaccaaaaggaagtattacctgcgggggtgaccattaaacaggagcagaacttg
gaccagacctacttggatgatgttaatgaaattatcaggaaggagttttcaggacctcct
gccagaaatcagacgtaa

KEGG   Homo sapiens (human): 4775Help
Entry
4775              CDS       T01001                                 

Gene name
NFATC3, NF-AT4c, NFAT4, NFATX
Definition
(RefSeq) nuclear factor of activated T cells 3
  KO
K17333  nuclear factor of activated T-cells, cytoplasmic 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04218  Cellular senescence
hsa04310  Wnt signaling pathway
hsa04360  Axon guidance
hsa04625  C-type lectin receptor signaling pathway
hsa04658  Th1 and Th2 cell differentiation
hsa04659  Th17 cell differentiation
hsa04660  T cell receptor signaling pathway
hsa04662  B cell receptor signaling pathway
hsa04921  Oxytocin signaling pathway
hsa05135  Yersinia infection
hsa05161  Hepatitis B
hsa05163  Human cytomegalovirus infection
hsa05166  Human T-cell leukemia virus 1 infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Network
nt06120  Calcium signaling (virus)
nt06124  Chemokine signaling (virus)
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165  Epstein-Barr virus (EBV)
nt06167  Human cytomegalovirus (HCMV)
nt06220  Calcium signaling
  Element
N00147  EGF-EGFR-PLCG-calcineurin signaling pathway
N00172  KSHV K15 to PLCG-calcineurin signaling pathway
N00180  KSHV K1 to PLCG-calcineurin signaling pathway
N00401  CXCR4-GNAQ-PLCB/G-calcineurin signaling pathway
N00402  HCMV US28 to GNAQ-PLCB/G-calcineurin signaling pathway
N00432  HIV gp120 to CXCR4-GNAQ-PLCB/G-calcineurin
N00487  BCR-PLCG-Calcineurin signaling pathway
N00490  HTLV-1 p12 to calcineurin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    4775 (NFATC3)
   04310 Wnt signaling pathway
    4775 (NFATC3)
   04022 cGMP-PKG signaling pathway
    4775 (NFATC3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    4775 (NFATC3)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    4775 (NFATC3)
   04660 T cell receptor signaling pathway
    4775 (NFATC3)
   04658 Th1 and Th2 cell differentiation
    4775 (NFATC3)
   04659 Th17 cell differentiation
    4775 (NFATC3)
   04662 B cell receptor signaling pathway
    4775 (NFATC3)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    4775 (NFATC3)
  09158 Development
   04360 Axon guidance
    4775 (NFATC3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    4775 (NFATC3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    4775 (NFATC3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    4775 (NFATC3)
   05170 Human immunodeficiency virus 1 infection
    4775 (NFATC3)
   05161 Hepatitis B
    4775 (NFATC3)
   05163 Human cytomegalovirus infection
    4775 (NFATC3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    4775 (NFATC3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    4775 (NFATC3)
Transcription factors [BR:hsa03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) NF-AT
    4775 (NFATC3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: RHD_dimer RHD_DNA_bind TIG
Motif
Other DBs
NCBI-GeneID: 4775
NCBI-ProteinID: NP_775188
OMIM: 602698
HGNC: 7777
Ensembl: ENSG00000072736
Vega: OTTHUMG00000137555
Pharos: Q12968(Tbio)
UniProt: Q12968 B5B2S1
LinkDB All DBs
Position
16q22.1
AA seq 1075 aa AA seqDB search
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL
CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC
HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS
SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS
PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS
PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD
DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL
DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM
FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP
HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI
VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV
PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM
IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG
LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD
QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA
SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE
PNFATIGLQDITLDDVNEIIGRDMSQISVSQGAGVSRQAPLPSPESLDLGRSDGL
NT seq 3228 nt NT seq  +upstreamnt  +downstreamnt
atgactactgcaaactgtggcgcccacgacgagctcgacttcaaactcgtctttggcgag
gacggggcgccggcgccgccgcccccgggctcgcggcctgcagatcttgagccagatgat
tgtgcatccatttacatctttaatgtagatccacctccatctactttaaccacaccactt
tgcttaccacatcatggattaccgtctcactcttctgttttgtcaccatcgtttcagctc
caaagtcacaaaaactatgaaggaacttgtgagattcctgaatctaaatatagcccatta
ggtggtcccaaaccctttgagtgcccaagtattcaaattacatctatctctcctaactgt
catcaagaattagatgcacatgaagatgacctacagataaatgacccagaacgggaattt
ttggaaaggccttctagagatcatctctatcttcctcttgagccatcctaccgggagtct
tctcttagtcctagtcctgccagcagcatctcttctaggagttggttctctgatgcatct
tcttgtgaatcgctttcacatatttatgatgatgtggactcagagttgaatgaagctgca
gcccgatttacccttggatcccctctgacttctcctggtggctctccagggggctgccct
ggagaagaaacttggcatcaacagtatggacttggacactcattatcacccaggcaatct
ccttgccactctcctagatccagtgtcactgatgagaattggctgagccccaggccagcc
tcaggaccctcatcaaggcccacatccccctgtgggaaacggaggcactccagtgctgaa
gtttgttatgctgggtccctttcaccccatcactcacctgttccttcacctggtcactcc
cccaggggaagtgtgacagaagatacgtggctcaatgcttctgtccatggtgggtcaggc
cttggccctgcagtttttccatttcagtactgtgtagagactgacatccctctcaaaaca
aggaaaacttctgaagatcaagctgccatactaccaggaaaattagagctgtgttcagat
gaccaagggagtttatcaccagcccgggagacttcaatagatgatggccttggatctcag
tatcctttaaagaaagattcatgtggtgatcagtttctttcagttccttcaccctttacc
tggagcaaaccaaagcctggccacacccctatatttcgcacatcttcattacctccacta
gactggcctttaccagctcattttggacaatgtgaactgaaaatagaagtgcaacctaaa
actcatcatcgagcccattatgaaactgaaggtagccgaggggcagtaaaagcatctact
gggggacatcctgttgtgaagctcctgggctataacgaaaagccaataaatctacaaatg
tttattgggacagcagatgatcgatatttacgacctcatgcattttaccaggtgcatcga
atcactgggaagacagtcgctactgcaagccaagagataataattgccagtacaaaagtt
ctggaaattccacttcttcctgaaaataatatgtcagccagtattgattgtgcaggtatt
ttgaaactccgcaattcagatatagaacttcgaaaaggagaaactgatattggcagaaag
aatactagagtacgacttgtgtttcgtgtacacatcccacagcccagtggaaaagtcctt
tctctgcagatagcctctatacccgttgagtgctcccagcggtctgctcaagaacttcct
catattgagaagtacagtatcaacagttgttctgtaaatggaggtcatgaaatggttgtg
actggatctaattttcttccagaatccaaaatcatttttcttgaaaaaggacaagatgga
cgacctcagtgggaggtagaagggaagataatcagggaaaaatgtcaaggggctcacatt
gtccttgaagttcctccatatcataacccagcagttacagctgcagtgcaggtgcacttt
tatctttgcaatggcaagaggaaaaaaagccagtctcaacgttttacttatacaccagtt
ttgatgaagcaagaacacagagaagagattgatttgtcttcagttccatctttgcctgtg
cctcatcctgctcagacccagaggccttcctctgattcagggtgttcacatgacagtgta
ctgtcaggacagagaagtttgatttgctccatcccacaaacatatgcatccatggtgacc
tcatcccatctgccacagttgcagtgtagagatgagagtgttagtaaagaacagcatatg
attccttctccaattgtacaccagccttttcaagtcacaccaacacctcctgtggggtct
tcctatcagcctatgcaaactaatgttgtgtacaatggaccaacttgtcttcctattaat
gctgcctctagtcaagaatttgattcagttttgtttcagcaggatgcaactctttctggt
ttagtgaatcttggctgtcaaccactgtcatccataccatttcattcttcaaattcaggc
tcaacaggacatctcttagcccatacacctcattctgtgcataccctgcctcatctgcaa
tcaatgggatatcattgttcaaatacaggacaaagatctctttcttctccagtggctgac
cagattacaggtcagccttcgtctcagttacaacctattacatatggtccttcacattca
gggtctgctacaacagcttccccagcagcttctcatcccttggctagttcaccgctttct
gggccaccatctcctcagcttcagcctatgccttaccaatctcctagctcaggaactgcc
tcatcaccgtctccagccaccagaatgcattctggacagcactcaactcaagcacaaagt
acgggccaggggggtctttctgcaccttcatccttaatatgtcacagtttgtgtgatcca
gcgtcatttccacctgatggggcaactgtgagcattaaacctgaaccagaagatcgagag
cctaactttgcaaccattggtctgcaggacatcactttagatgatgtgaacgagataatt
gggagagacatgtcccagatttctgtttcccaaggagcaggggtgagcaggcaggctccc
ctcccgagtcctgagtccctggatttaggaagatctgatgggctctaa

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