Homo sapiens (human): 4907
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Entry
4907 CDS
T01001
Gene name
NT5E, CALJA, CD73, E5NT, NT, NT5, NTE, eN, eNT
Definition
(RefSeq) 5'-nucleotidase ecto
KO
K19970
5'-nucleotidase [EC:
3.1.3.5
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00230
Purine metabolism
hsa00240
Pyrimidine metabolism
hsa00760
Nicotinate and nicotinamide metabolism
hsa01100
Metabolic pathways
Disease
H00824
Calcification of joints and arteries
Drug target
Oleclumab:
D10963
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
4907 (NT5E)
00240 Pyrimidine metabolism
4907 (NT5E)
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
4907 (NT5E)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hsa04090
]
4907 (NT5E)
00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:
hsa00537
]
4907 (NT5E)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.5 5'-nucleotidase
4907 (NT5E)
CD molecules [BR:
hsa04090
]
Proteins
4907 (NT5E)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:
hsa00537
]
Enzymes
4907 (NT5E)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
5_nucleotid_C
Metallophos
PGA_cap
Motif
Other DBs
NCBI-GeneID:
4907
NCBI-ProteinID:
NP_002517
OMIM:
129190
HGNC:
8021
Ensembl:
ENSG00000135318
Vega:
OTTHUMG00000015139
Pharos:
P21589
(Tbio)
UniProt:
P21589
Q6NZX3
LinkDB
All DBs
Structure
PDB:
4H2G
4H1Y
4H2B
4H2F
4H2I
4H1S
6HXW
Thumbnails
Position
6q14.3
AA seq
574 aa
AA seq
DB search
MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGG
VARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEF
DNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKE
TPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVV
GGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNV
ISSHGNPILLNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNM
GNLICDAMINNNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGT
FDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCR
VPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYP
AVEGRIKFSTGSHCHGSFSLIFLSLWAVIFVLYQ
NT seq
1725 nt
NT seq
+upstream
nt +downstream
nt
atgtgtccccgagccgcgcgggcgcccgcgacgctactcctcgccctgggcgcggtgctg
tggcctgcggctggcgcctgggagcttacgattttgcacaccaacgacgtgcacagccgg
ctggagcagaccagcgaggactccagcaagtgcgtcaacgccagccgctgcatgggtggc
gtggctcggctcttcaccaaggttcagcagatccgccgcgccgaacccaacgtgctgctg
ctggacgccggcgaccagtaccagggcactatctggttcaccgtgtacaagggcgccgag
gtggcgcacttcatgaacgccctgcgctacgatgccatggcactgggaaatcatgaattt
gataatggtgtggaaggactgatcgagccactcctcaaagaggccaaatttccaattctg
agtgcaaacattaaagcaaaggggccactagcatctcaaatatcaggactttatttgcca
tataaagttcttcctgttggtgatgaagttgtgggaatcgttggatacacttccaaagaa
accccttttctctcaaatccagggacaaatttagtgtttgaagatgaaatcactgcatta
caacctgaagtagataagttaaaaactctaaatgtgaacaaaattattgcactgggacat
tcgggttttgaaatggataaactcatcgctcagaaagtgaggggtgtggacgtcgtggtg
ggaggacactccaacacatttctttacacaggcaatccaccttccaaagaggtgcctgct
gggaagtacccattcatagtcacttctgatgatgggcggaaggttcctgtagtccaggcc
tatgcttttggcaaatacctaggctatctgaagatcgagtttgatgaaagaggaaacgtc
atctcttcccatggaaatcccattcttctaaacagcagcattcctgaagatccaagcata
aaagcagacattaacaaatggaggataaaattggataattattctacccaggaattaggg
aaaacaattgtctatctggatggctcctctcaatcatgccgctttagagaatgcaacatg
ggcaacctgatttgtgatgcaatgattaacaacaacctgagacacacggatgaaatgttc
tggaaccacgtatccatgtgcattttaaatggaggtggtatccggtcgcccattgatgaa
cgcaacaatggcacaattacctgggagaacctggctgctgtattgccctttggaggcaca
tttgacctagtccagttaaaaggttccaccctgaagaaggcctttgagcatagcgtgcac
cgctacggccagtccactggagagttcctgcaggtgggcggaatccatgtggtgtatgat
ctttcccgaaaacctggagacagagtagtcaaattagatgttctttgcaccaagtgtcga
gtgcccagttatgaccctctcaaaatggacgaggtatataaggtgatcctcccaaacttc
ctggccaatggtggagatgggttccagatgataaaagatgaattattaagacatgactct
ggtgaccaagatatcaacgtggtttctacatatatctccaaaatgaaagtaatttatcca
gcagttgaaggtcggatcaagttttccacaggaagtcactgccatggaagcttttcttta
atatttctttcactttgggcagtgatctttgttttataccaatag
DBGET
integrated database retrieval system
