Homo sapiens (human): 50618 Help Entry 50618             CDS       T01001                                  Symbol ITSN2, PRO2015, SH3D1B, SH3P18, SWA, SWAP Name (RefSeq) intersectin 2   KO K20045   intersectin Organism hsa  Homo sapiens (human) Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     50618 (ITSN2) Membrane trafficking [BR:hsa04131]  Endocytosis   Clathrin-mediated endocytosis    Other core components     50618 (ITSN2)   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     50618 (ITSN2)  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     50618 (ITSN2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PH_13 SH3_1 SH3_9 SH3_2 RhoGEF EF-hand_4 C2 EF-hand_1 EF-hand_7 PH EF-hand_8 INTAP Motif Other DBs NCBI-GeneID:  50618 NCBI-ProteinID:  NP_006268 OMIM:  604464 HGNC:  6184 Ensembl:  ENSG00000198399 UniProt:  Q9NZM3 A6H8W8 Structure PDB LinkDB All DBs Position 2:complement(24202864..24361368) Genome browser AA seq 1697 aa AA seqDB search MMAQFPTAMNGGPNMWAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLA EIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPLISARFGMG SMPNLSIPQPLPPAAPITSLSSATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQPLPI PYSSSTLPHGSSYSLMMGGFGGASIQKAQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAV PQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAE EFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLP VTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQL ELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEE IVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQL QQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLD ALEKETASKLSEMDSFNNQLKCGNMDDSVLQCLLSLLSCLNNLFLLLKELRETYNTQQLA LEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQ EEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNS GDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPKKALLPPTVSLSA TSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVEN LKAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWFGEVHGGRGWFPKSYVKIIPGSEVK REEPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTG SIGDRSGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLI LILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSERATPAFHPVCQVIAMYDYAA NNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVKMTTDSDPSQQWCADLQTL DTMQPIERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESGFLTEGEMALIFVNWKEL IMSNTKLLKALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGAALLQQKTD EDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKL ALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGK LYKTKSNKELHGFLFNDFLLLTYMVKQFAVSSGSEKLFSSKSNAQFKMYKTPIFLNEVLV KLPTDPSSDEPVFHISHIDRVYTLRTDNINERTAWVQKIKAASEQYIDTEKKKREKAYQA RSQKTSGIGRLMVHVIEATELKACKPNGKSNPYCEISMGSQSYTTRTIQDTLNPKWNFNC QFFIKDLYQDVLCLTLFDRDQFSPDDFLGRTEIPVAKIRTEQESKGPMTRRLLLHEVPTG EVWVRFDLQLFEQKTLL NT seq 5094 nt NT seq  +upstreamnt  +downstreamnt atgatggctcagtttcccacagctatgaatggagggccaaacatgtgggctattacctct gaagaacgtactaagcatgacaggcagtttgataacctcaaaccttcaggaggttacata acaggtgatcaagcacgtaattttttcctacaatcaggtctgccggcccctgttttagct gaaatatgggctttatcagacctaaacaaggatgggaagatggatcagcaagagttctcc atagctatgaaactcatcaaactgaagcttcaaggccaacagttgcctgtggttctccct cctattatgaagcaaccccctatgttttctccattaatttctgctcgttttggaatggga agcatgcccaatctgtccattcctcagccattgcctccagctgcacctataacatcattg tcttctgcgacttcagggaccaaccttcctcccttaatgatgcccactcccctagtgcct tctgttagcacatcatcattaccaaatggaaccgccagtctcattcagcctttacccatt ccttattcttcttcaacattgcctcatgggtcatcttatagtctgatgatgggaggattt ggaggtgctagtatacagaaagcgcagtctctgattgatttaggatctagtagctcaact tcctcgactgcttcactctcagggaactcacccaagactgggacctcagagtgggcagtt cctcagcctacaagattaaaatatcggcaaaaatttaatactcttgacaaaagtatgagt ggatatctctcaggttttcaagctagaaatgcccttcttcagtcaaatctttctcaaact cagctggctactatttggactctggctgacgttgatggtgatggacagctaaaagcagaa gagtttattcttgcaatgcaccttactgacatggccaaagctggacagccattaccactg actttacctcctgagcttgttcctccatctttcagaggaggaaagcaaattgattccatt aatggaactctgccttcatatcagaaaatgcaagaagaggagcctcagaagaaattacca gttacttttgaggacaaacggaaagccaactatgagcgagggaacatggagctggaaaag cgacgccaagccttgatggagcagcaacaaagggaggcagaacgtaaagcccagaaagaa aaggaagagtgggaacgaaaacagagagaattacaagaacaagaatggaagaaacaactt gaattagaaaaacgcttagagaagcaacgggaattggagagacaacgagaggaagaaagg agaaaagacatagaaagacgagaggcagcaaaacaggaacttgaacgacaacgtcgctta gaatgggagagaattcggcgacaggagcttctcaatcaaaagaatagagaacaagaagaa attgtcaggttaaactctaaaaagaagaatcttcatcttgagttggaagcactgaatggc aaacatcagcagatctcaggcagacttcaggatgtccgactcaaaaagcaaactcaaaag actgagctggaagttctggataagcagtgtgacttggaaattatggaaatcaagcaactt caacaggaacttcaggaatatcagaataagcttatctatctggtacctgagaagcaatta ttaaatgaaagaattaaaaacatgcagttcagtaacacacctgattcaggggtcagttta cttcataaaaaatcattagaaaaggaagaattatgccaaagacttaaagaacagttagat gctcttgaaaaagaaactgcatctaagctgtcagaaatggattcttttaacaatcaacta aagtgtgggaatatggatgactctgttcttcagtgccttttgtctctgctaagctgtctc aacaacctcttcctcttacttaaggaactgagagaaacctacaacacacagcagttagcc cttgaacagctttataagatcaaacgtgacaagttgaaggaaattgaaaggaaaagatta gaactaatgcagaaaaagaaactagaagatgaggctgcaaggaaagcaaagcaaggaaaa gaaaacttatggaaagaaaatcttagaaaggaggaagaagaaaaacaaaagcgactccag gaagaaaaaacacaagaaaaaattcaagaagaggaacggaaagctgaggagaaacaacgt aaggataaggatactttgaaagctgaggagaaaaaacgtgagacagctagtgttttggtg aattatagagcattatacccctttgaagcaaggaaccatgatgagatgagttttaattct ggagatataattcaggttgatgaaaaaaccgtaggagaacctggttggctttatggtagt tttcaaggaaattttggctggtttccatgcaattatgtagaaaaaatgccatcaagtgaa aatgaaaaagctgtatctccaaagaaggccttacttcctcctacagtttctttatctgct acctcaacttcctctgaaccactttcttcaaatcaaccagcatcagtgactgattatcaa aatgtatctttttcaaacctaactgtaaatacatcatggcagaaaaaatcagccttcact cgaactgtgtcccctggatctgtatcacctattcatggacagggacaagtggtagaaaac ttaaaagcacaggccctttgttcctggactgcaaagaaagataaccacttgaacttctca aaacatgacattattactgtcttggagcagcaagaaaattggtggtttggggaggtgcat ggaggaagaggatggtttcccaaatcttatgtcaagatcattcctgggagtgaagtaaaa cgggaagaaccagaagctttgtatgcagctgtaaataagaaacctacctcggcagcctat tcagttggagaagaatatattgcactttatccatattcaagtgtggaacctggagatttg actttcacagaaggtgaagaaatattggtgacccagaaagatggagagtggtggacagga agtattggagatagaagtggaatttttccatcaaactatgtcaaaccaaaggatcaagag agttttgggagtgctagcaagtctggagcatcaaataaaaaacctgagattgctcaggta acttcagcatatgttgcttctggttctgaacaacttagccttgcaccaggacagttaata ttaattctaaagaaaaatacaagtgggtggtggcaaggagagttacaggccagaggaaaa aagcgacagaaaggatggtttcctgccagtcatgttaaacttttgggtccaagtagtgaa agagccacacctgcctttcatcctgtatgtcaggtgattgctatgtatgactatgcagca aataatgaagatgagctcagtttctccaagggacaactcattaatgttatgaacaaagat gatcctgattggtggcaaggagagatcaacggggtgactggtctctttccttcaaactac gttaagatgacgacagactcagatccaagtcaacagtggtgtgctgatctgcaaaccctg gacacaatgcagccaattgagaggaaaagacagggctatattcatgagctgattcagacc gaagagcggtacatggctgaccttcagctcgtcgtcgaggtttttcagaaacgcatggca gagtcaggctttctcactgaaggggagatggccctgatttttgttaactggaaggagctc atcatgtccaacacaaagctgctgaaggctttgcgggtgcggaagaagaccgggggcgag aagatgccggtgcagatgattggggacatcctggccgctgagctgtcccacatgcaggct tacatcaggttctgcagctgccagcttaatggagcagctctgttacagcagaagacagat gaagacacagatttcaaagaatttttaaagaagctggcatctgacccgcggtgtaaagga atgcccctctccagcttcctgctgaaacccatgcagaggatcacccgctacccactgctc atcagaagtattctggagaacaccccggagagccatgcagaccattcctccctaaagctg gccctcgagcgggcagaggagctgtgctctcaagtgaatgagggagttcgggagaaggaa aactcggaccgactggagtggatccaggcgcacgtgcagtgtgaaggcctcgcggagcaa cttattttcaactctctcaccaactgcctggggccccggaagctcttacacagtgggaaa ttatacaagaccaagagcaacaaggaactgcacggattcctcttcaatgacttcctgctt cttacctacatggtcaagcagtttgctgtttcctctggctctgagaaacttttcagctcg aagtccaatgctcaattcaaaatgtataaaacgcccattttcctgaatgaagtcttggtg aaactgcccacagacccttccagcgatgagcctgtcttccacatttcccacattgatcgg gtctacaccctccgaacagacaacattaatgagaggaccgcctgggtgcagaagatcaag gcggcgtctgagcagtacatcgacaccgagaagaagaagcgtgagaaagcttaccaagcc cgctcccaaaagacttcaggcattgggcgcctgatggtgcatgtcattgaagctacagaa ttaaaagcctgcaaaccaaatggaaagagcaacccatactgtgaaatcagcatgggctcc cagagctacaccaccaggaccatccaggacacactcaatcccaagtggaattttaactgc cagttctttattaaggatctctaccaagacgtgctgtgtctcaccctgtttgacagagac cagttttcaccagatgatttcctgggtcgtactgaaattccagtggcaaaaattcgaaca gaacaggaaagcaaaggccctatgacccgccgactgctgctgcatgaggtccccaccggg gaggtctgggtccgttttgacctgcagctttttgagcaaaaaactctcctgtag

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