Homo sapiens (human): 5164
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Entry
5164 CDS
T01001
Symbol
PDK2, PDHK2, PDKII
Name
(RefSeq) pyruvate dehydrogenase kinase, isozyme 2 isoform 1 precursor
KO
K00898
pyruvate dehydrogenase kinase 2/3/4 [EC:
2.7.11.2
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa05415
Diabetic cardiomyopathy
Drug target
Sodium dichloroacetate:
D05857
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
5164 (PDK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
5164 (PDK2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.2 [pyruvate dehydrogenase (acetyl-transferring)] kinase
5164 (PDK2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: Other
PDHK family [OT]
5164 (PDK2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BCDHK_Adom3
HATPase_c
Motif
Other DBs
NCBI-GeneID:
5164
NCBI-ProteinID:
NP_002602
OMIM:
602525
HGNC:
8810
Ensembl:
ENSP00000420927.1
UniProt:
Q15119
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:50094737..50112152
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AA seq
407 aa
AA seq
DB search
MRWVWALLKNASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVR
LANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIR
NRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGST
NPAHPKHIGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVY
VPSHLYHMLFELFKNAMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKI
ERLFSYMYSTAPTPQPGTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYL
KALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS
NT seq
1224 nt
NT seq
+upstream
nt +downstream
nt
atgcgctgggtgtgggcgctgctgaagaatgcgtccctggcaggggcgcccaagtacata
gagcacttcagcaagttctccccgtccccgctgtccatgaagcagtttctggacttcgga
tccagcaatgcctgtgagaaaacctccttcaccttcctcaggcaggagctgcctgtgcgc
ctggccaacatcatgaaagagatcaacctgcttcccgaccgagtgctgagcacaccctcc
gtgcagctggtgcagagctggtatgtccagagcctcctggacatcatggagttcctggac
aaggatcccgaggaccatcgcaccctgagccagttcactgacgccctggtcaccatccgg
aaccggcacaacgacgtggtgcccaccatggcacaaggcgtgcttgagtacaaggacacc
tacggcgatgaccccgtctccaaccagaacatccagtacttcctggaccgcttctacctc
agccgcatctccatccgcatgctcatcaaccagcacaccctcatctttgatggcagcacc
aacccagcccatcccaaacacatcggcagcatcgaccccaactgcaacgtctctgaggtg
gtcaaagatgcctacgacatggctaagctcctgtgtgacaagtattacatggcctcacct
gacctggagatccaggagatcaatgcagccaactccaaacagccgattcacatggtctac
gtcccctcccacctctaccacatgctctttgagctcttcaagaatgccatgagggcgact
gtggaaagccatgagtccagcctcattctcccacccatcaaggtcatggtggccttgggt
gaggaagatctgtccatcaagatgagtgaccgaggtgggggtgttcccttgaggaagatt
gagcgactcttcagctacatgtactccacagcacccaccccccagcctggcaccggggga
acgccgctggctggctttggttatgggctccccatttcccgcctctacgccaagtacttc
cagggagacctgcagctcttctccatggaaggctttgggaccgatgctgtcatctatctc
aaggccctgtccacggactcggtggagcgcctgcctgtctacaacaagtcagcctggcgc
cactaccagaccatccaggaggccggcgactggtgtgtgcccagcacggagcccaagaac
acgtccacgtaccgcgtcagctaa
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