Homo sapiens (human): 5165
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Entry
5165 CDS
T01001
Symbol
PDK3, CMTX6, GS1-358P8.4
Name
(RefSeq) pyruvate dehydrogenase kinase 3
KO
K00898
pyruvate dehydrogenase kinase 2/3/4 [EC:
2.7.11.2
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa05415
Diabetic cardiomyopathy
Disease
H00264
Charcot-Marie-Tooth disease
Drug target
Sodium dichloroacetate:
D05857
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
5165 (PDK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
5165 (PDK3)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.2 [pyruvate dehydrogenase (acetyl-transferring)] kinase
5165 (PDK3)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: Other
PDHK family [OT]
5165 (PDK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BCDHK_Adom3
HATPase_c
CRM1_C
Motif
Other DBs
NCBI-GeneID:
5165
NCBI-ProteinID:
NP_005382
OMIM:
300906
HGNC:
8811
Ensembl:
ENSG00000067992
UniProt:
Q15120
Structure
PDB
PDBj
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All DBs
Position
X:24465286..24550466
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AA seq
406 aa
AA seq
DB search
MRLFRWLLKQPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANT
MREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPQVLDNFLQVLIKVRNRHN
DVVPTMAQGVIEYKEKFGFDPFISTNIQYFLDRFYTNRISFRMLINQHTLLFGGDTNPVH
PKHIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKAPDKPIQVVYVPSH
LFHMLFELFKNSMRATVELYEDRKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRL
FNYMYSTAPRPSLEPTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKA
LSSESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKAKQ
NT seq
1221 nt
NT seq
+upstream
nt +downstream
nt
atgcggctgttccggtggctgctgaagcagccggtgcccaagcagatcgagcgctactcg
cgcttttcgccgtcgccgctctccatcaaacaattcctggacttcgggagagataatgca
tgtgagaaaacttcatatatgtttctacgaaaggaacttcctgtgcggctggctaacaca
atgagagaagttaatcttctgccggataatttacttaaccgcccttcagtgggattggtt
cagagttggtatatgcagagttttcttgaacttttagaatatgaaaataagagccctgag
gatccacaggtcttggataactttctacaagttctgattaaagtcagaaatagacacaat
gatgtggttcctacaatggcacaaggagtgattgaatacaaggagaagtttgggtttgat
cctttcattagcactaacatccaatattttctggatcggttttataccaaccgcatctct
ttccgcatgcttattaatcagcacacacttctgtttgggggtgacactaatcctgttcat
cctaaacacataggaagtatcgatcccacctgtaacgtggcggatgtggtgaaagatgca
tatgaaacagccaagatgctgtgtgaacagtattacctggtagctccagagctggaagtt
gaagaattcaatgccaaagcgccagacaaacctattcaggtggtttatgtgccctcacat
ctgtttcatatgctatttgagttgttcaagaactcaatgagagcgacagttgaactctat
gaagacagaaaagagggctaccctgctgttaaaaccctcgttactttgggtaaagaagac
ttatccattaagatcagtgacctaggtggtggtgtcccacttcgaaaaatagatcgtctt
tttaactacatgtattctactgctcctagacccagcctggagcctaccagagctgcccct
ttggctggatttggttatggtttgccaatttcccgtctgtatgctagatattttcaagga
gatctgaaactgtattccatggaaggagtgggtactgatgctgtcatttatttgaaggct
ctttcaagtgagtcatttgagagacttccagtttttaataagtccgcatggcgccattac
aagaccacgcctgaagccgatgattggagcaatcccagcagtgaacccagggatgcttca
aaatacaaagcaaaacagtaa
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integrated database retrieval system
