Homo sapiens (human): 5205
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Entry
5205 CDS
T01001
Gene name
ATP8B1, ATPIC, BRIC, FIC1, ICP1, PFIC, PFIC1
Definition
(RefSeq) ATPase phospholipid transporting 8B1
KO
K01530
phospholipid-translocating ATPase [EC:
7.6.2.1
]
Organism
hsa
Homo sapiens (human)
Disease
H00624
Progressive familial intrahepatic cholestasis
H02192
Benign recurrent intrahepatic cholestasis
H02193
Intrahepatic cholestasis of pregnancy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09190 Not Included in Pathway or Brite
09191 Unclassified: metabolism
99980 Enzymes with EC numbers
5205 (ATP8B1)
Enzymes [BR:
hsa01000
]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.1 P-type phospholipid transporter
5205 (ATP8B1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PhoLip_ATPase_C
PhoLip_ATPase_N
Cation_ATPase
Hydrolase
E1-E2_ATPase
Hydrolase_3
MAP17
Motif
Other DBs
NCBI-GeneID:
5205
NCBI-ProteinID:
NP_005594
OMIM:
602397
HGNC:
3706
Ensembl:
ENSG00000081923
Vega:
OTTHUMG00000180255
Pharos:
O43520
(Tbio)
UniProt:
O43520
LinkDB
All DBs
Position
18q21.31
AA seq
1251 aa
AA seq
DB search
MSTERDSETTFDEDSQPNDEVVPYSDDETEDELDDQGSAVEPEQNRVNREAEENREPFRK
ECTWQVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAA
NLYFLALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEV
IKDGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFK
MSLEITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVI
RNTDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHA
YWEAQVGNSSWYLYDGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFIN
WDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHR
DASQHNHNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVD
RTDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDR
KRMSIIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLCYKE
IEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISK
LAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGGVYA
KFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQSKR
RLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNM
IKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFA
FTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYI
VGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIASAL
VITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNAL
RQPYIWLTIILAVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEEQWQRRQQVFRR
GVSTRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIVADGTAEYRRTGDS
NT seq
3756 nt
NT seq
+upstream
nt +downstream
nt
atgagtacagaaagagactcagaaacgacatttgacgaggattctcagcctaatgacgaa
gtggttccctacagtgatgatgaaacagaagatgaacttgatgaccaggggtctgctgtt
gaaccagaacaaaaccgagtcaacagggaagcagaggagaaccgggagccattcagaaaa
gaatgtacatggcaagtcaaagcaaacgatcgcaagtaccacgaacaacctcactttatg
aacacaaaattcttgtgtattaaggagagtaaatatgcgaataatgcaattaaaacatac
aagtacaacgcatttacctttataccaatgaatctgtttgagcagtttaagagagcagcc
aatttatatttcctggctcttcttatcttacaggcagttcctcaaatctctaccctggct
tggtacaccacactagtgcccctgcttgtggtgctgggcgtcactgcaatcaaagacctg
gtggacgatgtggctcgccataaaatggataaggaaatcaacaataggacgtgtgaagtc
attaaggatggcaggttcaaagttgctaagtggaaagaaattcaagttggagacgtcatt
cgtctgaaaaaaaatgattttgttccagctgacattctcctgctgtctagctctgagcct
aacagcctctgctatgtggaaacagcagaactggatggagaaaccaatttaaaatttaag
atgtcacttgaaatcacagaccagtacctccaaagagaagatacattggctacatttgat
ggttttattgaatgtgaagaacccaataacagactagataagtttacaggaacactattt
tggagaaacacaagttttcctttggatgctgataaaattttgttacgtggctgtgtaatt
aggaacaccgatttctgccacggcttagtcatttttgcaggtgctgacactaaaataatg
aagaatagtgggaaaaccagatttaaaagaactaaaattgattacttgatgaactacatg
gtttacacgatctttgttgttcttattctgctttctgctggtcttgccatcggccatgct
tattgggaagcacaggtgggcaattcctcttggtacctctatgatggagaagacgataca
ccctcctaccgtggattcctcattttctggggctatatcattgttctcaacaccatggta
cccatctctctctatgtcagcgtggaagtgattcgtcttggacagagtcacttcatcaac
tgggacctgcaaatgtactatgctgagaaggacacacccgcaaaagctagaaccaccaca
ctcaatgaacagctcgggcagatccattatatcttctctgataagacggggacactcaca
caaaatatcatgacctttaaaaagtgctgtatcaacgggcagatatatggggaccatcgg
gatgcctctcaacacaaccacaacaaaatagagcaagttgattttagctggaatacatat
gctgatgggaagcttgcattttatgaccactatcttattgagcaaatccagtcagggaaa
gagccagaagtacgacagttcttcttcttgctcgcagtttgccacacagtcatggtggat
aggactgatggtcagctcaactaccaggcagcctctcccgatgaaggtgccctggtaaac
gctgccaggaactttggctttgccttcctcgccaggacccagaacaccatcaccatcagt
gaactgggcactgaaaggacttacaatgttcttgccattttggacttcaacagtgaccgg
aagcgaatgtctatcattgtaagaaccccagaaggcaatatcaagctttactgtaaaggt
gctgacactgttatttatgaacggttacatcgaatgaatcctactaagcaagaaacacag
gatgccctggatatctttgcaaatgaaactcttagaaccctatgcctttgctacaaggaa
attgaagaaaaagaatttacagaatggaataaaaagtttatggctgccagtgtggcctcc
accaaccgggacgaagctctggataaagtatatgaggagattgaaaaagacttaattctc
ctgggagctacagctattgaagacaagctacaggatggagttccagaaaccatttcaaaa
cttgcaaaagctgacattaagatctgggtgcttactggagacaaaaaggaaactgctgaa
aatataggatttgcttgtgaacttctgactgaagacaccaccatctgctatggggaggat
attaattctcttcttcatgcaaggatggaaaaccagaggaatagaggtggcgtctacgca
aagtttgcacctcctgtgcaggaatctttttttccacccggtggaaaccgtgccttaatc
atcactggttcttggttgaatgaaattcttctcgagaaaaagaccaagagaaataagatt
ctgaagctgaagttcccaagaacagaagaagaaagacggatgcggacccaaagtaaaagg
aggctagaagctaagaaagagcagcggcagaaaaactttgtggacctggcctgcgagtgc
agcgcagtcatctgctgccgcgtcacccccaagcagaaggccatggtggtggacctggtg
aagaggtacaagaaagccatcacgctggccatcggagatggggccaatgacgtgaacatg
atcaaaactgcccacattggcgttggaataagtggacaagaaggaatgcaagctgtcatg
tcgagtgactattcctttgctcagttccgatatctgcagaggctactgctggtgcatggc
cgatggtcttacataaggatgtgcaagttcctacgatacttcttttacaaaaactttgcc
tttactttggttcatttctggtactccttcttcaatggctactctgcgcagactgcatac
gaggattggttcatcaccctctacaacgtgctgtacaccagcctgcccgtgctcctcatg
gggctgctcgaccaggatgtgagtgacaaactgagcctccgattccctgggttatacata
gtgggacaaagagacttactattcaactataagagattctttgtaagcttgttgcatggg
gtcctaacatcgatgatcctcttcttcatacctcttggagcttatctgcaaaccgtaggg
caggatggagaggcaccttccgactaccagtcttttgccgtcaccattgcctctgctctt
gtaataacagtcaatttccagattggcttggatacttcttattggacttttgtgaatgct
ttttcaatttttggaagcattgcactttattttggcatcatgtttgactttcatagtgct
ggaatacatgttctctttccatctgcatttcaatttacaggcacagcttcaaacgctctg
agacagccatacatttggttaactatcatcctggctgttgctgtgtgcttactacccgtc
gttgccattcgattcctgtcaatgaccatctggccatcagaaagtgataagatccagaag
catcgcaagcggttgaaggcggaggagcagtggcagcgacggcagcaggtgttccgccgg
ggcgtgtcaacgcggcgctcggcctacgccttctcgcaccagcggggctacgcggacctc
atctcctccgggcgcagcatccgcaagaagcgctcgccgcttgatgccatcgtggcggat
ggcaccgcggagtacaggcgcaccggggacagctga
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integrated database retrieval system
