KEGG   Homo sapiens (human): 5230Help
Entry
5230              CDS       T01001                                 

Gene name
PGK1, HEL-S-68p, MIG10, PGKA
Definition
(RefSeq) phosphoglycerate kinase 1
  KO
K00927  phosphoglycerate kinase [EC:2.7.2.3]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00010  Glycolysis / Gluconeogenesis
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01230  Biosynthesis of amino acids
hsa04066  HIF-1 signaling pathway
Module
hsa_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
hsa_M00002  Glycolysis, core module involving three-carbon compounds
hsa_M00003  Gluconeogenesis, oxaloacetate => fructose-6P
Network
nt06017  Glycogen metabolism
  Element
N00731  Glycolysis
N00733  LDHA deficiency in glycolysis
N00735  ENO3 deficiency in glycolysis
N00737  PGAM2 deficiency in glycolysis
Disease
H00664  Anemia due to disorders of glycolytic enzymes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    5230 (PGK1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    5230 (PGK1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5230 (PGK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.3  phosphoglycerate kinase
     5230 (PGK1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   5230 (PGK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PGK DUF3172
Motif
Other DBs
NCBI-GeneID: 5230
NCBI-ProteinID: NP_000282
OMIM: 311800
HGNC: 8896
Ensembl: ENSG00000102144
Vega: OTTHUMG00000021888
Pharos: P00558(Tbio)
UniProt: P00558 V9HWF4
LinkDB All DBs
Structure
PDB: 

Position
Xq21.1
AA seq 417 aa AA seqDB search
MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL
MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE
NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN
LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM
AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ
ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV
KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI
NT seq 1254 nt NT seq  +upstreamnt  +downstreamnt
atgtcgctttctaacaagctgacgctggacaagctggacgttaaagggaagcgggtcgtt
atgagagtcgacttcaatgttcctatgaagaacaaccagataacaaacaaccagaggatt
aaggctgctgtcccaagcatcaaattctgcttggacaatggagccaagtcggtagtcctt
atgagccacctaggccggcctgatggtgtgcccatgcctgacaagtactccttagagcca
gttgctgtagaactcaaatctctgctgggcaaggatgttctgttcttgaaggactgtgta
ggcccagaagtggagaaagcctgtgccaacccagctgctgggtctgtcatcctgctggag
aacctccgctttcatgtggaggaagaagggaagggaaaagatgcttctgggaacaaggtt
aaagccgagccagccaaaatagaagctttccgagcttcactttccaagctaggggatgtc
tatgtcaatgatgcttttggcactgctcacagagcccacagctccatggtaggagtcaat
ctgccacagaaggctggtgggtttttgatgaagaaggagctgaactactttgcaaaggcc
ttggagagcccagagcgacccttcctggccatcctgggcggagctaaagttgcagacaag
atccagctcatcaataatatgctggacaaagtcaatgagatgattattggtggtggaatg
gcttttaccttccttaaggtgctcaacaacatggagattggcacttctctgtttgatgaa
gagggagccaagattgtcaaagacctaatgtccaaagctgagaagaatggtgtgaagatt
accttgcctgttgactttgtcactgctgacaagtttgatgagaatgccaagactggccaa
gccactgtggcttctggcatacctgctggctggatgggcttggactgtggtcctgaaagc
agcaagaagtatgctgaggctgtcactcgggctaagcagattgtgtggaatggtcctgtg
ggggtatttgaatgggaagcttttgcccggggaaccaaagctctcatggatgaggtggtg
aaagccacttctaggggctgcatcaccatcataggtggtggagacactgccacttgctgt
gccaaatggaacacggaggataaagtcagccatgtgagcactgggggtggtgccagtttg
gagctcctggaaggtaaagtccttcctggggtggatgctctcagcaatatttag

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