Homo sapiens (human): 53637
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Entry
53637 CDS
T01001
Symbol
S1PR5, EDG8, Edg-8, S1P5, SPPR-1, SPPR-2
Name
(RefSeq) sphingosine-1-phosphate receptor 5
KO
K04295
sphingosine 1-phosphate receptor 5
Organism
hsa
Homo sapiens (human)
Pathway
hsa04071
Sphingolipid signaling pathway
hsa04080
Neuroactive ligand-receptor interaction
Drug target
Amiselimod (
DG02399
):
D10904
D10905
Etrasimod (
DG02444
):
D10930
D10931
<US>
Ozanimod (
DG02827
):
D10967
<JP/US>
D10968
Siponimod (
DG03018
):
D11072
<JP/US>
D11460
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04071 Sphingolipid signaling pathway
53637 (S1PR5)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
53637 (S1PR5)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
53637 (S1PR5)
G protein-coupled receptors [BR:
hsa04030
]
Rhodopsin family
Lipid
Sphingolipid
53637 (S1PR5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_1
7TM_GPCR_Srsx
Motif
Other DBs
NCBI-GeneID:
53637
NCBI-ProteinID:
NP_001159687
OMIM:
605146
HGNC:
14299
Ensembl:
ENSG00000180739
UniProt:
Q9H228
Structure
PDB
PDBj
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All DBs
Position
19:complement(10512742..10517965)
Genome browser
AA seq
398 aa
AA seq
DB search
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
NT seq
1197 nt
NT seq
+upstream
nt +downstream
nt
atggagtcggggctgctgcggccggcgccggtgagcgaggtcatcgtcctgcattacaac
tacaccggcaagctccgcggtgcgcgctaccagccgggtgccggcctgcgcgccgacgcc
gtggtgtgcctggcggtgtgcgccttcatcgtgctagagaatctagccgtgttgttggtg
ctcggacgccacccgcgcttccacgctcccatgttcctgctcctgggcagcctcacgttg
tcggatctgctggcaggcgccgcctacgccgccaacatcctactgtcggggccgctcacg
ctgaaactgtcccccgcgctctggttcgcacgggagggaggcgtcttcgtggcactcact
gcgtccgtgctgagcctcctggccatcgcgctggagcgcagcctcaccatggcgcgcagg
gggcccgcgcccgtctccagtcgggggcgcacgctggcgatggcagccgcggcctggggc
gtgtcgctgctcctcgggctcctgccagcgctgggctggaattgcctgggtcgcctggac
gcttgctccactgtcttgccgctctacgccaaggcctacgtgctcttctgcgtgctcgcc
ttcgtgggcatcctggccgctatctgtgcactctacgcgcgcatctactgccaggtacgc
gccaacgcgcggcgcctgccggcacggcccgggactgcggggaccacctcgacccgggcg
cgtcgcaagccgcgctcgctggccttgctgcgcacgctcagcgtggtgctcctggccttt
gtggcatgttggggccccctcttcctgctgctgttgctcgacgtggcgtgcccggcgcgc
acctgtcctgtactcctgcaggccgatcccttcctgggactggccatggccaactcactt
ctgaaccccatcatctacacgctcaccaaccgcgacctgcgccacgcgctcctgcgcctg
gtctgctgcggacgccactcctgcggcagagacccgagtggctcccagcagtcggcgagc
gcggctgaggcttccgggggcctgcgccgctgcctgcccccgggccttgatgggagcttc
agcggctcggagcgctcatcgccccagcgcgacgggctggacaccagcggctccacaggc
agccccggtgcacccacagccgcccggactctggtatcagaaccggctgcagactga
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