Homo sapiens (human): 5585
Entry
5585 CDS
T01001
Gene name
PKN1, DBK, PAK-1, PAK1, PKN, PKN-ALPHA, PRK1, PRKCL1
Definition
(RefSeq) protein kinase N1
KO
K06071
serine/threonine-protein kinase N1 [EC:
2.7.11.13
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04151
PI3K-Akt signaling pathway
hsa04621
NOD-like receptor signaling pathway
hsa05132
Salmonella infection
hsa05135
Yersinia infection
Network
nt06139
NLR signaling (viruses and bacteria)
Element
N00866
Yersinia YopM to Pyrin Inflammasome signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
5585 (PKN1)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
5585 (PKN1)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
5585 (PKN1)
05135 Yersinia infection
5585 (PKN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
5585 (PKN1)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.13 protein kinase C
5585 (PKN1)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: AGC group
PKN family
5585 (PKN1)
SSDB
Motif
Pfam:
Pkinase
HR1
Pkinase_Tyr
Pkinase_C
Kinase-like
PL48
Uds1
Haspin_kinase
C2
Other DBs
NCBI-GeneID:
5585
NCBI-ProteinID:
NP_002732
OMIM:
601032
HGNC:
9405
Ensembl:
ENSG00000123143
Vega:
OTTHUMG00000039611
Pharos:
Q16512
(Tchem)
UniProt:
Q16512
LinkDB
Structure
PDB:
4OTH
4OTI
4OTD
1CXZ
4OTG
4NKG
2RMK
1URF
Position
19p13.12
AA seq
942 aa
MASDAVQSEPRSWSLLEQLGLAGADLAAPGVQQQLELERERLRREIRKELKLKEGAENLR
RATTDLGRSLGPVELLLRGSSRRLDLLHQQLQELHAHVVLPDPAATHDGPQSPGAGGPTC
SATNLSRVAGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLTAQQMLQDSKTKIDII
RMQLRRALQAGQLENQAAPDDTQGSPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLS
AAKAPDRKAVSEAQEKLTESNQKLGLLREALERRLGELPADHPKGRLLREELAAASSAAF
STRLAGPFPATHYSTLCKPAPLTGTLEVRVVGCRDLPETIPWNPTPSMGGPGTPDSRPPF
LSRPARGLYSRSGSLSGRSSLKAEAENTSEVSTVLKLDNTVVGQTSWKPCGPNAWDQSFT
LELERARELELAVFWRDQRGLCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPV
IERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRLIPNATGTGTFSPGASPGS
EARTTGDISVEKLNLGTDSDSSPQKSSRDPPSSPSSLSSPIQESTAPELPSETQETPGPA
LCSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESL
MCEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAIFY
SACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPE
FLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSA
EAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTD
VSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFLDFDFVAGGC
NT seq
2829 nt
+upstream
nt +downstream
nt
atggccagcgacgccgtgcagagtgagcctcgcagctggtccctgctagagcagctgggc
ctggccggggcagacctggcggcccccggggtacagcagcagctggagctggagcgggag
cggctgcggcgggaaatccgcaaggagctgaagctgaaggagggtgctgagaacctgcgg
cgggccaccactgacctgggccgcagcctgggccccgtagagctgctgctgcggggctcc
tcgcgccgcctcgacctgctgcaccagcagctgcaggagctgcacgcccacgtggtgctt
cccgacccggcggccacccacgatggcccccagtcccctggtgcgggtggccccacctgc
tcggccaccaacctgagccgcgtggcgggcctggagaagcagttggccattgagctgaag
gtgaagcagggggcggagaacatgatccagacctacagcaatggcagcaccaaggaccgg
aagctgctgctgacagcccagcagatgttgcaggacagtaagaccaagattgacatcatc
cgcatgcaactccgccgggcgctgcaggccggccagctggagaaccaggcagccccggat
gacacccaagggagtcctgacctgggggctgtggagctgcgcatcgaagagctgcggcac
cacttccgagtggagcacgcggtggccgagggtgccaagaacgtactgcgcctgctcagc
gctgccaaggccccggaccgcaaggcagtcagcgaggcccaggagaaattaacagaatcc
aaccagaagctggggctgctgcgggaggctctggagcggagacttggggagctgcccgcc
gaccaccccaaggggcggctgctgcgagaagagctcgctgcggcctcctccgctgccttc
agcacccgcctggccgggccctttcccgccacgcactacagcaccctgtgcaagcccgcg
ccgctcacagggaccctggaggtacgagtggtgggctgcagagacctcccagagaccatc
ccgtggaaccctaccccctcaatggggggacctgggaccccagacagccgcccccccttc
ctgagccgcccagcccggggcctttacagccgaagcggaagcctcagtggccggagcagc
ctcaaagcagaagccgagaacaccagtgaagtcagcactgtgcttaagctggataacaca
gtggtggggcagacgtcttggaagccatgtggccccaatgcctgggaccagagcttcact
ctggagctggaaagggcacgggaactggagttggctgtgttctggcgggaccagcggggc
ctgtgtgccctcaaattcctgaagttggaggatttcttggacaatgagaggcatgaggtg
cagctggacatggaaccccagggctgcctggtggctgaggtcaccttccgcaaccctgtc
attgagaggattcctcggctccgacggcagaagaaaattttctccaagcagcaagggaag
gcgttccagcgtgctaggcagatgaacatcgatgtcgccacgtgggtgcggctgctccgg
aggctcatccccaatgccacgggcacaggcacctttagccctggggcttctccaggatcc
gaggcccggaccacgggtgacatatcggtggagaagctgaacctcggcactgactcggac
agctcacctcagaagagctcgcgggatcctccttccagcccatcgagcctgagctccccc
atccaggaatccactgctcccgagctgccttcggagacccaggagaccccaggccccgcc
ctgtgcagccctctgaggaagtcacctctgaccctcgaagatttcaagttcctggcggtg
ctgggccggggtcattttgggaaggtgctcctctccgaattccggcccagtggggagctg
ttcgccatcaaggctctgaagaaaggggacattgtggcccgagacgaggtggagagcctg
atgtgtgagaagcggatattggcggcagtgaccagtgcgggacaccccttcctggtgaac
ctcttcggctgtttccagacaccggagcacgtgtgcttcgtgatggagtactcggccggt
ggggacctgatgctgcacatccacagcgacgtgttctctgagccccgtgccatcttttat
tccgcctgcgtggtgctgggcctacagtttcttcacgaacacaagatcgtctacagggac
ctgaagttggacaatttgctcctggacaccgagggctacgtcaagatcgcagactttggc
ctctgcaaggaggggatgggctatggggaccggaccagcacattctgtgggaccccggag
ttcctggcccctgaggtgctgacggacacgtcgtacacgcgagctgtggactggtgggga
ctgggtgtgctgctctacgagatgctggttggcgagtccccattcccaggggatgatgag
gaggaggtcttcgacagcatcgtcaacgacgaggttcgctacccccgcttcctgtcggcc
gaagccatcggcatcatgagaaggctgcttcggaggaacccagagcggaggctgggatct
agcgagagagatgcagaagatgtgaagaaacagcccttcttcaggactctgggctgggaa
gccctgttggcccggcgcctgccaccgccctttgtgcccacgctgtccggccgcaccgac
gtcagcaacttcgacgaggagttcaccggggaggcccccacactgagcccgccccgcgac
gcgcggcccctcacagccgcggagcaggcagccttcctggacttcgacttcgtggccggg
ggctgctag
DBGET
integrated database retrieval system
