KEGG   Homo sapiens (human): 5610Help
Entry
5610              CDS       T01001                                 

Gene name
EIF2AK2, EIF2AK1, PKR, PPP1R83, PRKR
Definition
(RefSeq) eukaryotic translation initiation factor 2 alpha kinase 2
  KO
K16195  eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04217  Necroptosis
hsa05160  Hepatitis C
hsa05162  Measles
hsa05164  Influenza A
hsa05165  Human papillomavirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05168  Herpes simplex virus 1 infection
hsa05169  Epstein-Barr virus infection
hsa05203  Viral carcinogenesis
Network
nt06122  IFN signaling (viruses)
nt06138  PKR-eIF2alpha signaling (viruses)
nt06162  Hepatitis B virus (HBV)
nt06163  Hepatitis C virus (HCV)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165  Epstein-Barr virus (EBV)
nt06166  Human papillomavirus (HPV)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06169  Measles virus (MV)
nt06170  Influenza A virus (IAV)
nt06222  IFN signaling
nt06263  Hepatocellular carcinoma
  Element
N00150  Type I IFN signaling pathway
N00261  KSHV vIRF2 to IFN signaling pathway
N00270  HCV Core to IFN signaling pathway
N00377  HPV E6 to IFN signaling pathway
N00378  HPV E6 to IFN signaling pathway
N00379  HPV E7 to IFN signaling pathway
N00471  EBV LMP2A/2B to IFN signaling pathway
N00472  EBV LMP1 to IFN signaling pathway
N00473  EBV BGLF4 to IFN signaling pathway
N00571  PKR-eIF2alpha signaling pathway
N00573  HSV US11 to PKR-eIF2alpha signaling pathway
N00575  HSV ICP27 to IFN signaling pathway
N00576  HSV UL41/UL13 to IFN signaling pathway
N00577  HSV UL41 to IFN signaling pathway
N00578  HSV UL41 to IFN signaling pathway
N00693  MV V/P to IFN signaling pathway
N00694  MV V/P/C to IFN signaling pathway
N00696  MV C to PKR-eIF2alpha signaling pathway
N00725  IAV NS1 to PKR-eIF2alpha signaling pathway
N00726  IAV NP to PKR-eIF2alpha signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    5610 (EIF2AK2)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    5610 (EIF2AK2)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    5610 (EIF2AK2)
  09172 Infectious disease: viral
   05162 Measles
    5610 (EIF2AK2)
   05164 Influenza A
    5610 (EIF2AK2)
   05160 Hepatitis C
    5610 (EIF2AK2)
   05168 Herpes simplex virus 1 infection
    5610 (EIF2AK2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    5610 (EIF2AK2)
   05169 Epstein-Barr virus infection
    5610 (EIF2AK2)
   05165 Human papillomavirus infection
    5610 (EIF2AK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    5610 (EIF2AK2)
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5610 (EIF2AK2)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    5610 (EIF2AK2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     5610 (EIF2AK2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  PEK family [OT]
   5610 (EIF2AK2)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     5610 (EIF2AK2)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     5610 (EIF2AK2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr dsrm Kinase-like Kdo DND1_DSRM Pkinase_fungal FTA2
Motif
Other DBs
NCBI-GeneID: 5610
NCBI-ProteinID: NP_001129123
OMIM: 176871
HGNC: 9437
Ensembl: ENSG00000055332
Vega: OTTHUMG00000100962
Pharos: P19525(Tbio)
UniProt: P19525 Q8IW76
LinkDB All DBs
Structure
PDB: 

Position
2p22.2
AA seq 551 aa AA seqDB search
MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK
KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ
CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG
SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK
RSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKY
NNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTK
CLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNI
FLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAE
LLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWK
KSPEKNERHTC
NT seq 1656 nt NT seq  +upstreamnt  +downstreamnt
atggctggtgatctttcagcaggtttcttcatggaggaacttaatacataccgtcagaag
cagggagtagtacttaaatatcaagaactgcctaattcaggacctccacatgataggagg
tttacatttcaagttataatagatggaagagaatttccagaaggtgaaggtagatcaaag
aaggaagcaaaaaatgccgcagccaaattagctgttgagatacttaataaggaaaagaag
gcagttagtcctttattattgacaacaacgaattcttcagaaggattatccatggggaat
tacataggccttatcaatagaattgcccagaagaaaagactaactgtaaattatgaacag
tgtgcatcgggggtgcatgggccagaaggatttcattataaatgcaaaatgggacagaaa
gaatatagtattggtacaggttctactaaacaggaagcaaaacaattggccgctaaactt
gcatatcttcagatattatcagaagaaacctcagtgaaatctgactacctgtcctctggt
tcttttgctactacgtgtgagtcccaaagcaactctttagtgaccagcacactcgcttct
gaatcatcatctgaaggtgacttctcagcagatacatcagagataaattctaacagtgac
agtttaaacagttcttcgttgcttatgaatggtctcagaaataatcaaaggaaggcaaaa
agatctttggcacccagatttgaccttcctgacatgaaagaaacaaagtatactgtggac
aagaggtttggcatggattttaaagaaatagaattaattggctcaggtggatttggccaa
gttttcaaagcaaaacacagaattgacggaaagacttacgttattaaacgtgttaaatat
aataacgagaaggcggagcgtgaagtaaaagcattggcaaaacttgatcatgtaaatatt
gttcactacaatggctgttgggatggatttgattatgatcctgagaccagtgatgattct
cttgagagcagtgattatgatcctgagaacagcaaaaatagttcaaggtcaaagactaag
tgccttttcatccaaatggaattctgtgataaagggaccttggaacaatggattgaaaaa
agaagaggcgagaaactagacaaagttttggctttggaactctttgaacaaataacaaaa
ggggtggattatatacattcaaaaaaattaattcatagagatcttaagccaagtaatata
ttcttagtagatacaaaacaagtaaagattggagactttggacttgtaacatctctgaaa
aatgatggaaagcgaacaaggagtaagggaactttgcgatacatgagcccagaacagatt
tcttcgcaagactatggaaaggaagtggacctctacgctttggggctaattcttgctgaa
cttcttcatgtatgtgacactgcttttgaaacatcaaagtttttcacagacctacgggat
ggcatcatctcagatatatttgataaaaaagaaaaaactcttctacagaaattactctca
aagaaacctgaggatcgacctaacacatctgaaatactaaggaccttgactgtgtggaag
aaaagcccagagaaaaatgaacgacacacatgttag

KEGG   Homo sapiens (human): 4938Help
Entry
4938              CDS       T01001                                 

Gene name
OAS1, E18/E16, IFI-4, OIAS, OIASI
Definition
(RefSeq) 2'-5'-oligoadenylate synthetase 1
  KO
K14216  2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
hsa05160  Hepatitis C
hsa05162  Measles
hsa05164  Influenza A
hsa05168  Herpes simplex virus 1 infection
hsa05169  Epstein-Barr virus infection
Network
nt06122  IFN signaling (viruses)
nt06137  OAS/RNase L pathway (viruses)
nt06163  Hepatitis C virus (HCV)
nt06165  Epstein-Barr virus (EBV)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06169  Measles virus (MV)
nt06170  Influenza A virus (IAV)
nt06222  IFN signaling
nt06263  Hepatocellular carcinoma
  Element
N00270  HCV Core to IFN signaling pathway
N00273  HCV NS5A to oligoadenylate synthetase (OAS)/RNase L pathway
N00471  EBV LMP2A/2B to IFN signaling pathway
N00472  EBV LMP1 to IFN signaling pathway
N00473  EBV BGLF4 to IFN signaling pathway
N00515  Oligoadenylate synthetase (OAS)/RNase L pathway
N00574  HSV US11 to oligoadenylate synthetase (OAS)/RNase L pathway
N00575  HSV ICP27 to IFN signaling pathway
N00576  HSV UL41/UL13 to IFN signaling pathway
N00577  HSV UL41 to IFN signaling pathway
N00578  HSV UL41 to IFN signaling pathway
N00693  MV V/P to IFN signaling pathway
N00694  MV V/P/C to IFN signaling pathway
N00724  IAV NS1 to oligoadenylate synthetase (OAS)/RNase L pathway
N00738  IAV NS1 to IFN signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    4938 (OAS1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    4938 (OAS1)
   05164 Influenza A
    4938 (OAS1)
   05160 Hepatitis C
    4938 (OAS1)
   05168 Herpes simplex virus 1 infection
    4938 (OAS1)
   05169 Epstein-Barr virus infection
    4938 (OAS1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.84  2'-5' oligoadenylate synthase
     4938 (OAS1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: OAS1_C NTP_transf_2 SMODS PKcGMP_CC
Motif
Other DBs
NCBI-GeneID: 4938
NCBI-ProteinID: NP_058132
OMIM: 164350
HGNC: 8086
Ensembl: ENSG00000089127
Vega: OTTHUMG00000169792
Pharos: P00973(Tbio)
UniProt: P00973
LinkDB All DBs
Structure
PDB: 

Position
12q24.13
AA seq 400 aa AA seqDB search
MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVK
GGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFE
VQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDL
QKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAW
ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD
PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLAESNSADDETDDPR
RYQKYGYIGTHEYPHFSHRPSTLQAASTPQAEEDWTCTIL
NT seq 1203 nt NT seq  +upstreamnt  +downstreamnt
atgatggatctcagaaataccccagccaaatctctggacaagttcattgaagactatctc
ttgccagacacgtgtttccgcatgcaaatcaaccatgccattgacatcatctgtgggttc
ctgaaggaaaggtgcttccgaggtagctcctaccctgtgtgtgtgtccaaggtggtaaag
ggtggctcctcaggcaagggcaccaccctcagaggccgatctgacgctgacctggttgtc
ttcctcagtcctctcaccacttttcaggatcagttaaatcgccggggagagttcatccag
gaaattaggagacagctggaagcctgtcaaagagagagagcattttccgtgaagtttgag
gtccaggctccacgctggggcaacccccgtgcgctcagcttcgtactgagttcgctccag
ctcggggagggggtggagttcgatgtgctgcctgcctttgatgccctgggtcagttgact
ggcggctataaacctaacccccaaatctatgtcaagctcatcgaggagtgcaccgacctg
cagaaagagggcgagttctccacctgcttcacagaactacagagagacttcctgaagcag
cgccccaccaagctcaagagcctcatccgcctagtcaagcactggtaccaaaattgtaag
aagaagcttgggaagctgccacctcagtatgccctggagctcctgacggtctatgcttgg
gagcgagggagcatgaaaacacatttcaacacagcccagggatttcggacggtcttggaa
ttagtcataaactaccagcaactctgcatctactggacaaagtattatgactttaaaaac
cccattattgaaaagtacctgagaaggcagctcacgaaacccaggcctgtgatcctggac
ccggcggaccctacaggaaacttgggtggtggagacccaaagggttggaggcagctggca
caagaggctgaggcctggctgaattacccatgctttaagaattgggatgggtccccagtg
agctcctggattctgctggctgaaagcaacagtgcagacgatgagaccgacgatcccagg
aggtatcagaaatatggttacattggaacacatgagtaccctcatttctctcatagaccc
agcacactccaggcagcatccaccccacaggcagaagaggactggacctgcaccatcctc
tga

KEGG   Homo sapiens (human): 4939Help
Entry
4939              CDS       T01001                                 

Gene name
OAS2
Definition
(RefSeq) 2'-5'-oligoadenylate synthetase 2
  KO
K14216  2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
hsa05160  Hepatitis C
hsa05162  Measles
hsa05164  Influenza A
hsa05168  Herpes simplex virus 1 infection
hsa05169  Epstein-Barr virus infection
Network
nt06122  IFN signaling (viruses)
nt06137  OAS/RNase L pathway (viruses)
nt06163  Hepatitis C virus (HCV)
nt06165  Epstein-Barr virus (EBV)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06169  Measles virus (MV)
nt06170  Influenza A virus (IAV)
nt06222  IFN signaling
nt06263  Hepatocellular carcinoma
  Element
N00270  HCV Core to IFN signaling pathway
N00273  HCV NS5A to oligoadenylate synthetase (OAS)/RNase L pathway
N00471  EBV LMP2A/2B to IFN signaling pathway
N00472  EBV LMP1 to IFN signaling pathway
N00473  EBV BGLF4 to IFN signaling pathway
N00515  Oligoadenylate synthetase (OAS)/RNase L pathway
N00574  HSV US11 to oligoadenylate synthetase (OAS)/RNase L pathway
N00575  HSV ICP27 to IFN signaling pathway
N00576  HSV UL41/UL13 to IFN signaling pathway
N00577  HSV UL41 to IFN signaling pathway
N00578  HSV UL41 to IFN signaling pathway
N00693  MV V/P to IFN signaling pathway
N00694  MV V/P/C to IFN signaling pathway
N00724  IAV NS1 to oligoadenylate synthetase (OAS)/RNase L pathway
N00738  IAV NS1 to IFN signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    4939 (OAS2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    4939 (OAS2)
   05164 Influenza A
    4939 (OAS2)
   05160 Hepatitis C
    4939 (OAS2)
   05168 Herpes simplex virus 1 infection
    4939 (OAS2)
   05169 Epstein-Barr virus infection
    4939 (OAS2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.84  2'-5' oligoadenylate synthase
     4939 (OAS2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: OAS1_C NTP_transf_2 SMODS
Motif
Other DBs
NCBI-GeneID: 4939
NCBI-ProteinID: NP_058197
OMIM: 603350
HGNC: 8087
Ensembl: ENSG00000111335
Vega: OTTHUMG00000169802
Pharos: P29728(Tbio)
UniProt: P29728
LinkDB All DBs
Position
12q24.13
AA seq 719 aa AA seqDB search
MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG
GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI
QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC
FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD
NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN
VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK
CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS
YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF
DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK
DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT
QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA
KEWLSSPCFKDGTGNPIPPWKVPTMQTPGSCGARIHPIVNEMFSSRSHRILNNNSKRNF
NT seq 2160 nt NT seq  +upstreamnt  +downstreamnt
atgggaaatggggagtcccagctgtcctcggtgcctgctcagaagctgggttggtttatc
caggaatacctgaagccctacgaagaatgtcagacactgatcgacgagatggtgaacacc
atctgtgacgtcctgcaggaacccgaacagttccccctggtgcagggagtggccataggt
ggctcctatggacggaaaacagtcttaagaggcaactccgatggtacccttgtcctcttc
ttcagtgacttaaaacaattccaggatcagaagagaagccaacgtgacatcctcgataaa
actggggataagctgaagttctgtctgttcacgaagtggttgaaaaacaatttcgagatc
cagaagtcccttgatgggttcaccatccaggtgttcacaaaaaatcagagaatctctttc
gaggtgctggccgccttcaacgctctgagcttaaatgataatcccagcccctggatctat
cgagagctcaaaagatccttggataagacaaatgccagtcctggtgagtttgcagtctgc
ttcactgaactccagcagaagttttttgacaaccgtcctggaaaactaaaggatttgatc
ctcttgataaagcactggcatcaacagtgccagaaaaaaatcaaggatttaccctcgctg
tctccgtatgccctggagctgcttacggtgtatgcctgggaacaggggtgcagaaaagac
aactttgacattgctgaaggcgtcagaaccgtactggagctgatcaaatgccaggagaag
ctgtgtatctattggatggtcaactacaactttgaagatgagaccatcaggaacatcctg
ctgcaccagctccaatcagcgaggccagtaatcttggatccagttgacccaaccaataat
gtgagtggagataaaatatgctggcaatggctgaaaaaagaagctcaaacctggttgact
tctcccaacctggataatgagttacctgcaccatcttggaatgttctgcctgcaccactc
ttcacgaccccaggccaccttctggataagttcatcaaggagtttctccagcccaacaaa
tgcttcctagagcagattgacagtgctgttaacatcatccgtacattccttaaagaaaac
tgcttccgacaatcaacagccaagatccagattgtccggggaggatcaaccgccaaaggc
acagctctgaagactggctctgatgccgatctcgtcgtgttccataactcacttaaaagc
tacacctcccaaaaaaacgagcggcacaaaatcgtcaaggaaatccatgaacagctgaaa
gccttttggagggagaaggaggaggagcttgaagtcagctttgagcctcccaagtggaag
gctcccagggtgctgagcttctctctgaaatccaaagtcctcaacgaaagtgtcagcttt
gatgtgcttcctgcctttaatgcactgggtcagctgagttctggctccacacccagcccc
gaggtttatgcagggctcattgatctgtataaatcctcggacctcccgggaggagagttt
tctacctgtttcacagtcctgcagcgaaacttcattcgctcccggcccaccaaactaaag
gatttaattcgcctggtgaagcactggtacaaagagtgtgaaaggaaactgaagccaaag
gggtctttgcccccaaagtatgccttggagctgctcaccatctatgcctgggagcagggg
agtggagtgccggattttgacactgcagaaggtttccggacagtcctggagctggtcaca
caatatcagcagctctgcatcttctggaaggtcaattacaactttgaagatgagaccgtg
aggaagtttctactgagccagttgcagaaaaccaggcctgtgatcttggacccagccgaa
cccacaggtgacgtgggtggaggggaccgttggtgttggcatcttctggcaaaagaagca
aaggaatggttatcctctccctgcttcaaggatgggactggaaacccaataccaccttgg
aaagtgccgacaatgcagacaccaggaagttgtggagctaggatccatcctattgtcaat
gagatgttctcatccagaagccatagaatcctgaataataattctaaaagaaacttctag

KEGG   Homo sapiens (human): 4940Help
Entry
4940              CDS       T01001                                 

Gene name
OAS3, p100, p100OAS
Definition
(RefSeq) 2'-5'-oligoadenylate synthetase 3
  KO
K14216  2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
hsa05160  Hepatitis C
hsa05162  Measles
hsa05164  Influenza A
hsa05168  Herpes simplex virus 1 infection
hsa05169  Epstein-Barr virus infection
Network
nt06122  IFN signaling (viruses)
nt06137  OAS/RNase L pathway (viruses)
nt06163  Hepatitis C virus (HCV)
nt06165  Epstein-Barr virus (EBV)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06169  Measles virus (MV)
nt06170  Influenza A virus (IAV)
nt06222  IFN signaling
nt06263  Hepatocellular carcinoma
  Element
N00270  HCV Core to IFN signaling pathway
N00273  HCV NS5A to oligoadenylate synthetase (OAS)/RNase L pathway
N00471  EBV LMP2A/2B to IFN signaling pathway
N00472  EBV LMP1 to IFN signaling pathway
N00473  EBV BGLF4 to IFN signaling pathway
N00515  Oligoadenylate synthetase (OAS)/RNase L pathway
N00574  HSV US11 to oligoadenylate synthetase (OAS)/RNase L pathway
N00575  HSV ICP27 to IFN signaling pathway
N00576  HSV UL41/UL13 to IFN signaling pathway
N00577  HSV UL41 to IFN signaling pathway
N00578  HSV UL41 to IFN signaling pathway
N00693  MV V/P to IFN signaling pathway
N00694  MV V/P/C to IFN signaling pathway
N00724  IAV NS1 to oligoadenylate synthetase (OAS)/RNase L pathway
N00738  IAV NS1 to IFN signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    4940 (OAS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    4940 (OAS3)
   05164 Influenza A
    4940 (OAS3)
   05160 Hepatitis C
    4940 (OAS3)
   05168 Herpes simplex virus 1 infection
    4940 (OAS3)
   05169 Epstein-Barr virus infection
    4940 (OAS3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.84  2'-5' oligoadenylate synthase
     4940 (OAS3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: OAS1_C NTP_transf_2 SMODS Polbeta
Motif
Other DBs
NCBI-GeneID: 4940
NCBI-ProteinID: NP_006178
OMIM: 603351
HGNC: 8088
Ensembl: ENSG00000111331
Vega: OTTHUMG00000169795
Pharos: Q9Y6K5(Tbio)
UniProt: Q9Y6K5
LinkDB All DBs
Structure
PDB: 

Position
12q24.13
AA seq 1087 aa AA seqDB search
MDLYSTPAAALDRFVARRLQPRKEFVEKARRALGALAAALRERGGRLGAAAPRVLKTVKG
GSSGRGTALKGGCDSELVIFLDCFKSYVDQRARRAEILSEMRASLESWWQNPVPGLRLTF
PEQSVPGALQFRLTSVDLEDWMDVSLVPAFNVLGQAGSGVKPKPQVYSTLLNSGCQGGEH
AACFTELRRNFVNIRPAKLKNLILLVKHWYHQVCLQGLWKETLPPVYALELLTIFAWEQG
CKKDAFSLAEGLRTVLGLIQQHQHLCVFWTVNYGFEDPAVGQFLQRQLKRPRPVILDPAD
PTWDLGNGAAWHWDLLAQEAASCYDHPCFLRGMGDPVQSWKGPGLPRAGCSGLGHPIQLD
PNQKTPENSKSLNAVYPRAGSKPPSCPAPGPTGAASIVPSVPGMALDLSQIPTKELDRFI
QDHLKPSPQFQEQVKKAIDIILRCLHENCVHKASRVSKGGSFGRGTDLRDGCDVELIIFL
NCFTDYKDQGPRRAEILDEMRAQLESWWQDQVPSLSLQFPEQNVPEALQFQLVSTALKSW
TDVSLLPAFDAVGQLSSGTKPNPQVYSRLLTSGCQEGEHKACFAELRRNFMNIRPVKLKN
LILLVKHWYRQVAAQNKGKGPAPASLPPAYALELLTIFAWEQGCRQDCFNMAQGFRTVLG
LVQQHQQLCVYWTVNYSTEDPAMRMHLLGQLRKPRPLVLDPADPTWNVGHGSWELLAQEA
AALGMQACFLSRDGTSVQPWDVMPALLYQTPAGDLDKFISEFLQPNRQFLAQVNKAVDTI
CSFLKENCFRNSPIKVIKVVKGGSSAKGTALRGRSDADLVVFLSCFSQFTEQGNKRAEII
SEIRAQLEACQQERQFEVKFEVSKWENPRVLSFSLTSQTMLDQSVDFDVLPAFDALGQLV
SGSRPSSQVYVDLIHSYSNAGEYSTCFTELQRDFIISRPTKLKSLIRLVKHWYQQCTKIS
KGRGSLPPQHGLELLTVYAWEQGGKDSQFNMAEGFRTVLELVTQYRQLCIYWTINYNAKD
KTVGDFLKQQLQKPRPIILDPADPTGNLGHNARWDLLAKEAAACTSALCCMGRNGIPIQP
WPVKAAV
NT seq 3264 nt NT seq  +upstreamnt  +downstreamnt
atggacttgtacagcaccccggccgctgcgctggacaggttcgtggccagaaggctgcag
ccgcggaaggagttcgtagagaaggcgcggcgcgctctgggcgccctggccgctgccctg
agggagcgcgggggccgcctcggtgctgctgccccgcgggtgctgaaaactgtcaaggga
ggctcctcgggccggggcacagctctcaagggtggctgtgattctgaacttgtcatcttc
ctcgactgcttcaagagctatgtggaccagagggcccgccgtgcagagatcctcagtgag
atgcgggcatcgctggaatcctggtggcagaacccagtccctggtctgagactcacgttt
cctgagcagagcgtgcctggggccctgcagttccgcctgacatccgtagatcttgaggac
tggatggatgttagcctggtgcctgccttcaatgtcctgggtcaggccggctccggcgtc
aaacccaagccacaagtctactctaccctcctcaacagtggctgccaagggggcgagcat
gcggcctgcttcacagagctgcggaggaactttgtgaacattcgcccagccaagttgaag
aacctaatcttgctggtgaagcactggtaccaccaggtgtgcctacaggggttgtggaag
gagacgctgcccccggtctatgccctggaattgctgaccatcttcgcctgggagcagggc
tgtaagaaggatgctttcagcctagccgaaggcctccgaactgtcctgggcctgatccaa
cagcatcagcacctgtgtgttttctggactgtcaactatggcttcgaggaccctgcagtt
gggcagttcttgcagcggcagcttaagagacccaggcctgtgatcctggacccagctgac
cccacatgggacctggggaatggggcagcctggcactgggatttgctagcccaggaggca
gcatcctgctatgaccacccatgctttctgagggggatgggggacccagtgcagtcttgg
aaggggccgggccttccacgtgctggatgctcaggtttgggccaccccatccagctagac
cctaaccagaagacccctgaaaacagcaagagcctcaatgctgtgtacccaagagcaggg
agcaaacctccctcatgcccagctcctggccccactggggcagccagcatcgtcccctct
gtgccgggaatggccttggacctgtctcagatccccaccaaggagctggaccgcttcatc
caggaccacctgaagccgagcccccagttccaggagcaggtgaaaaaggccattgacatc
atcttgcgctgcctccatgagaactgtgttcacaaggcctcaagagtcagtaaagggggc
tcatttggccggggcacagacctaagggatggctgtgatgttgaactcatcatcttcctc
aactgcttcacggactacaaggaccaggggccccgccgcgcagagatccttgatgagatg
cgagcgcagctagaatcctggtggcaggaccaggtgcccagcctgagccttcagtttcct
gagcagaatgtgcctgaggctctgcagttccagctggtgtccacagccctgaagagctgg
acggatgttagcctgctgcctgccttcgatgctgtggggcagctcagttctggcaccaaa
ccaaatccccaggtctactcgaggctcctcaccagtggctgccaggagggcgagcataag
gcctgcttcgcagagctgcggaggaacttcatgaacattcgccctgtcaagctgaagaac
ctgattctgctggtgaagcactggtaccgccaggttgcggctcagaacaaaggaaaagga
ccagcccctgcctctctgcccccagcctatgccctggagctcctcaccatctttgcctgg
gagcagggctgcaggcaggattgtttcaacatggcccaaggcttccggacggtgctgggg
ctcgtgcaacagcatcagcagctctgtgtctactggacggtcaactatagcactgaggac
ccagccatgagaatgcaccttcttggccagcttcgaaaacccagacccctggtcctggac
cccgctgatcccacctggaacgtgggccacggtagctgggagctgttggcccaggaagca
gcagcgctggggatgcaggcctgctttctgagtagagacgggacatctgtgcagccctgg
gatgtgatgccagccctcctttaccaaaccccagctggggaccttgacaagttcatcagt
gaatttctccagcccaaccgccagttcctggcccaggtgaacaaggccgttgataccatc
tgttcatttttgaaggaaaactgcttccggaattctcccatcaaagtgatcaaggtggtc
aagggtggctcttcagccaaaggcacagctctgcgaggccgctcagatgccgacctcgtg
gtgttcctcagctgcttcagccagttcactgagcagggcaacaagcgggccgagatcatc
tccgagatccgagcccagctggaggcatgtcaacaggagcggcagttcgaggtcaagttt
gaagtctccaaatgggagaatccccgcgtgctgagcttctcactgacatcccagacgatg
ctggaccagagtgtggactttgatgtgctgccagcctttgacgccctaggccagctggtc
tctggctccaggcccagctctcaagtctacgtcgacctcatccacagctacagcaatgcg
ggcgagtactccacctgcttcacagagctacaacgggacttcatcatctctcgccctacc
aagctgaagagcctgatccggctggtgaagcactggtaccagcagtgtaccaagatctcc
aaggggagaggctccctacccccacagcacgggctggaactcctgactgtgtatgcctgg
gagcagggcgggaaggactcccagttcaacatggctgagggcttccgcacggtcctggag
ctggtcacccagtaccgccagctctgtatctactggaccatcaactacaacgccaaggac
aagactgttggagacttcctgaaacagcagcttcagaagcccaggcctatcatcctggat
ccggctgacccgacaggcaacctgggccacaatgcccgctgggacctgctggccaaggaa
gctgcagcctgcacatctgccctgtgctgcatgggacggaatggcatccccatccagcca
tggccagtgaaggctgctgtgtga

KEGG   Homo sapiens (human): 3665Help
Entry
3665              CDS       T01001                                 

Gene name
IRF7, IMD39, IRF-7, IRF-7H, IRF7A, IRF7B, IRF7C, IRF7H
Definition
(RefSeq) interferon regulatory factor 7
  KO
K09447  interferon regulatory factor 7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04620  Toll-like receptor signaling pathway
hsa04621  NOD-like receptor signaling pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa04623  Cytosolic DNA-sensing pathway
hsa05160  Hepatitis C
hsa05161  Hepatitis B
hsa05162  Measles
hsa05164  Influenza A
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05168  Herpes simplex virus 1 infection
hsa05169  Epstein-Barr virus infection
hsa05203  Viral carcinogenesis
Network
nt06121  TLR signaling (viruses and bacteria)
nt06122  IFN signaling (viruses)
nt06133  RIG-I signaling (viruses)
nt06162  Hepatitis B virus (HBV)
nt06163  Hepatitis C virus (HCV)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165  Epstein-Barr virus (EBV)
nt06166  Human papillomavirus (HPV)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06169  Measles virus (MV)
nt06170  Influenza A virus (IAV)
nt06221  TLR signaling
nt06222  IFN signaling
nt06263  Hepatocellular carcinoma
  Element
N00148  TLR3-IRF7 signaling pathway
N00150  Type I IFN signaling pathway
N00162  KSHV vIRF3 to TLR3-IRF7 signaling pathway
N00163  KSHV KIE1/2 to TLR3-IRF7 signaling pathway
N00261  KSHV vIRF2 to IFN signaling pathway
N00268  HBV HBx to RIG-I-like receptor signaling pathway
N00271  HCV NS3/4A to RIG-I-like receptor signaling pathway
N00469  RIG-I-IRF7/3 signaling pathway
N00471  EBV LMP2A/2B to IFN signaling pathway
N00472  EBV LMP1 to IFN signaling pathway
N00473  EBV BGLF4 to IFN signaling pathway
N00516  HCV NS3/4A to TLR3-IRF3 signaling pathway
N00553  TLR4-IRF3/7 signaling pathway
N00554  HBV HBe to TLR4-IRF3/7 signaling pathway
N00555  HBV HBe to TLR4-IRF3/7 signaling pathway
N00565  HSV US11 to RIG-I-like receptor signaling pathway
N00566  HSV UL36USP to RIG-I-like receptor signaling pathway
N00567  HSV ICP34.5 to TBK1 signaling pathway
N00685  MV V to RIG-I-IRF7/3 signaling pathway
N00690  TLR7/9-IRF7 signaling pathway
N00691  MV V to TLR7/9-IRF7 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    3665 (IRF7)
   04621 NOD-like receptor signaling pathway
    3665 (IRF7)
   04622 RIG-I-like receptor signaling pathway
    3665 (IRF7)
   04623 Cytosolic DNA-sensing pathway
    3665 (IRF7)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    3665 (IRF7)
  09172 Infectious disease: viral
   05162 Measles
    3665 (IRF7)
   05164 Influenza A
    3665 (IRF7)
   05161 Hepatitis B
    3665 (IRF7)
   05160 Hepatitis C
    3665 (IRF7)
   05168 Herpes simplex virus 1 infection
    3665 (IRF7)
   05167 Kaposi sarcoma-associated herpesvirus infection
    3665 (IRF7)
   05169 Epstein-Barr virus infection
    3665 (IRF7)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    3665 (IRF7)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Tryptophan clusters interferon-regulating factors
    3665 (IRF7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: IRF-3 IRF
Motif
Other DBs
NCBI-GeneID: 3665
NCBI-ProteinID: NP_001563
OMIM: 605047
HGNC: 6122
Ensembl: ENSG00000185507
Vega: OTTHUMG00000132019
Pharos: Q92985(Tbio)
UniProt: Q92985
LinkDB All DBs
Position
11p15.5
AA seq 503 aa AA seqDB search
MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIF
KAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHK
VYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKG
DLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAV
ETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTV
LQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLE
LRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRAR
QRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSL
CLSSANSLYDDIECFLMELEQPA
NT seq 1512 nt NT seq  +upstreamnt  +downstreamnt
atggccttggctcctgagagggcagccccacgcgtgctgttcggagagtggctccttgga
gagatcagcagcggctgctatgaggggctgcagtggctggacgaggcccgcacctgtttc
cgcgtgccctggaagcacttcgcgcgcaaggacctgagcgaggccgacgcgcgcatcttc
aaggcctgggctgtggcccgcggcaggtggccgcctagcagcaggggaggtggcccgccc
cccgaggctgagactgcggagcgcgccggctggaaaaccaacttccgctgcgcactgcgc
agcacgcgtcgcttcgtgatgctgcgggataactcgggggacccggccgacccgcacaag
gtgtacgcgctcagccgggagctgtgctggcgagaaggcccaggcacggaccagactgag
gcagaggcccccgcagctgtcccaccaccacagggtgggcccccagggccattcctggca
cacacacatgctggactccaagccccaggccccctccctgccccagctggtgacaagggg
gacctcctgctccaggcagtgcaacagagctgcctggcagaccatctgctgacagcgtca
tggggggcagatccagtcccaaccaaggctcctggagagggacaagaagggcttcccctg
actggggcctgtgctggaggcccagggctccctgctggggagctgtacgggtgggcagta
gagacgacccccagccccgggccccagcccgcggcactaacgacaggcgaggccgcggcc
ccagagtccccgcaccaggcagagccgtacctgtcaccctccccaagcgcctgcaccgcg
gtgcaagagcccagcccaggggcgctggacgtgaccatcatgtacaagggccgcacggtg
ctgcagaaggtggtgggacacccgagctgcacgttcctatacggccccccagacccagct
gtccgggccacagacccccagcaggtagcattccccagccctgccgagctcccggaccag
aagcagctgcgctacacggaggaactgctgcggcacgtggcccctgggttgcacctggag
cttcgggggccacagctgtgggcccggcgcatgggcaagtgcaaggtgtactgggaggtg
ggcggacccccaggctccgccagcccctccaccccagcctgcctgctgcctcggaactgt
gacacccccatcttcgacttcagagtcttcttccaagagctggtggaattccgggcacgg
cagcgccgtggctccccacgctataccatctacctgggcttcgggcaggacctgtcagct
gggaggcccaaggagaagagcctggtcctggtgaagctggaaccctggctgtgccgagtg
cacctagagggcacgcagcgtgagggtgtgtcttccctggatagcagcagcctcagcctc
tgcctgtccagcgccaacagcctctatgacgacatcgagtgcttccttatggagctggag
cagcccgcctag

KEGG   Homo sapiens (human): 3627Help
Entry
3627              CDS       T01001                                 

Gene name
CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1
Definition
(RefSeq) C-X-C motif chemokine ligand 10
  KO
K12671  C-X-C motif chemokine 10
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04061  Viral protein interaction with cytokine and cytokine receptor
hsa04062  Chemokine signaling pathway
hsa04620  Toll-like receptor signaling pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa04623  Cytosolic DNA-sensing pathway
hsa04657  IL-17 signaling pathway
hsa04668  TNF signaling pathway
hsa05160  Hepatitis C
hsa05164  Influenza A
hsa05169  Epstein-Barr virus infection
Network
nt06122  IFN signaling (viruses)
nt06165  Epstein-Barr virus (EBV)
  Element
N00471  EBV LMP2A/2B to IFN signaling pathway
N00472  EBV LMP1 to IFN signaling pathway
N00473  EBV BGLF4 to IFN signaling pathway
Disease
H01360  Allergic rhinitis
Drug target
Eldelumab: D10404
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    3627 (CXCL10)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    3627 (CXCL10)
   04061 Viral protein interaction with cytokine and cytokine receptor
    3627 (CXCL10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    3627 (CXCL10)
   04622 RIG-I-like receptor signaling pathway
    3627 (CXCL10)
   04623 Cytosolic DNA-sensing pathway
    3627 (CXCL10)
   04657 IL-17 signaling pathway
    3627 (CXCL10)
   04062 Chemokine signaling pathway
    3627 (CXCL10)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    3627 (CXCL10)
   05160 Hepatitis C
    3627 (CXCL10)
   05169 Epstein-Barr virus infection
    3627 (CXCL10)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:hsa04052]
    3627 (CXCL10)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    3627 (CXCL10)
Cytokines and growth factors [BR:hsa04052]
 Cytokines
  Chemokines
   3627 (CXCL10)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Haparin
  Chemokines
   3627 (CXCL10)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: IL8
Motif
Other DBs
NCBI-GeneID: 3627
NCBI-ProteinID: NP_001556
OMIM: 147310
HGNC: 10637
Ensembl: ENSG00000169245
Vega: OTTHUMG00000160887
Pharos: P02778(Tbio)
UniProt: P02778
LinkDB All DBs
Structure
PDB: 

Position
4q21.1
AA seq 98 aa AA seqDB search
MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRV
EIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP
NT seq 297 nt NT seq  +upstreamnt  +downstreamnt
atgaatcaaactgccattctgatttgctgccttatctttctgactctaagtggcattcaa
ggagtacctctctctagaactgtacgctgtacctgcatcagcattagtaatcaacctgtt
aatccaaggtctttagaaaaacttgaaattattcctgcaagccaattttgtccacgtgtt
gagatcattgctacaatgaaaaagaagggtgagaagagatgtctgaatccagaatcgaag
gccatcaagaatttactgaaagcagttagcaaggaaaggtctaaaagatctccttaa

KEGG   Homo sapiens (human): 9636Help
Entry
9636              CDS       T01001                                 

Gene name
ISG15, G1P2, IFI15, IMD38, IP17, UCRP, hUCRP
Definition
(RefSeq) ISG15 ubiquitin like modifier
  KO
K12159  ubiquitin cross-reactive protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa05165  Human papillomavirus infection
hsa05169  Epstein-Barr virus infection
Network
nt06122  IFN signaling (viruses)
nt06165  Epstein-Barr virus (EBV)
nt06166  Human papillomavirus (HPV)
  Element
N00377  HPV E6 to IFN signaling pathway
N00378  HPV E6 to IFN signaling pathway
N00379  HPV E7 to IFN signaling pathway
N00471  EBV LMP2A/2B to IFN signaling pathway
N00472  EBV LMP1 to IFN signaling pathway
N00473  EBV BGLF4 to IFN signaling pathway
Disease
H00089  IFN-gamma/IL-12 axis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    9636 (ISG15)
 09160 Human Diseases
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    9636 (ISG15)
   05165 Human papillomavirus infection
    9636 (ISG15)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    9636 (ISG15)
Ubiquitin system [BR:hsa04121]
 Ubiquitins and ubiquitin-like proteins
  Ubiquitin-like proteins (UBLs)
   9636 (ISG15)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: ubiquitin Rad60-SLD Ubiquitin_2 Ubiquitin_5 DUF2407
Motif
Other DBs
NCBI-GeneID: 9636
NCBI-ProteinID: NP_005092
OMIM: 147571
HGNC: 4053
Ensembl: ENSG00000187608
Vega: OTTHUMG00000040777
Pharos: P05161(Tbio)
UniProt: P05161
LinkDB All DBs
Structure
PDB: 

Position
1p36.33
AA seq 165 aa AA seqDB search
MGWDLTVKMLAGNEFQVSLSSSMSVSELKAQITQKIGVHAFQQRLAVHPSGVALQDRVPL
ASQGLGPGSTVLLVVDKCDEPLSILVRNNKGRSSTYEVRLTQTVAHLKQQVSGLEGVQDD
LFWLTFEGKPLEDQLPLGEYGLKPLSTVFMNLRLRGGGTEPGGRS
NT seq 498 nt NT seq  +upstreamnt  +downstreamnt
atgggctgggacctgacggtgaagatgctggcgggcaacgaattccaggtgtccctgagc
agctccatgtcggtgtcagagctgaaggcgcagatcacccagaagatcggcgtgcacgcc
ttccagcagcgtctggctgtccacccgagcggtgtggcgctgcaggacagggtccccctt
gccagccagggcctgggccccggcagcacggtcctgctggtggtggacaaatgcgacgaa
cctctgagcatcctggtgaggaataacaagggccgcagcagcacctacgaggtacggctg
acgcagaccgtggcccacctgaagcagcaagtgagcgggctggagggtgtgcaggacgac
ctgttctggctgaccttcgaggggaagcccctggaggaccagctcccgctgggggagtac
ggcctcaagcccctgagcaccgtgttcatgaatctgcgcctgcggggaggcggcacagag
cctggcgggcggagctaa

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