Homo sapiens (human): 5617 Help Entry 5617              CDS       T01001                                  Gene name PRL, GHA1 Definition (RefSeq) prolactin   KO K05439   prolactin Organism hsa  Homo sapiens (human) Pathway hsa04060   Cytokine-cytokine receptor interaction hsa04080   Neuroactive ligand-receptor interaction hsa04151   PI3K-Akt signaling pathway hsa04630   JAK-STAT signaling pathway hsa04917   Prolactin signaling pathway Network nt06325  PRL signaling   Element N00920   PRL-JAK-STAT signaling pathway N00921   Mutation-inactivated PRLR to PRL-JAK-STAT signaling pathway Drug target Bromocriptine (DG00452):  D00780<JP/US> D03165 Cabergoline:  D00987<JP/US> Terguride:  D01348 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     5617 (PRL)    04151 PI3K-Akt signaling pathway     5617 (PRL)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     5617 (PRL)    04060 Cytokine-cytokine receptor interaction     5617 (PRL)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     5617 (PRL)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hsa04052]     5617 (PRL) Cytokines and growth factors [BR:hsa04052]  Cytokines   CSF and other factors    5617 (PRL) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hormone_1 Motif Other DBs NCBI-GeneID:  5617 NCBI-ProteinID:  NP_000939 OMIM:  176760 HGNC:  9445 Ensembl:  ENSG00000172179 Vega:  OTTHUMG00000016111 Pharos:  P01236(Tbio) CPD:  C18201 UniProt:  P01236 Q5THQ0 LinkDB All DBs Structure PDB:  3NCE 3N06 3NCB 3N0P 3MZG 3NCC 3D48 2Q98 3NCF 3NPZ 3EW3 1RW5 Thumbnails Position 6p22.3 AA seq 227 aa AA seqDB search MNIKGSPWKGSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNL SSEMFSEFDKRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWN EPLYHLVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSG LPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNNNC NT seq 684 nt NT seq  +upstreamnt  +downstreamnt atgaacatcaaaggatcgccatggaaagggtccctcctgctgctgctggtgtcaaacctg ctcctgtgccagagcgtggcccccttgcccatctgtcccggcggggctgcccgatgccag gtgacccttcgagacctgtttgaccgcgccgtcgtcctgtcccactacatccataacctc tcctcagaaatgttcagcgaattcgataaacggtatacccatggccgggggttcattacc aaggccatcaacagctgccacacttcttcccttgccacccccgaagacaaggagcaagcc caacagatgaatcaaaaagactttctgagcctgatagtcagcatattgcgatcctggaat gagcctctgtatcatctggtcacggaagtacgtggtatgcaagaagccccggaggctatc ctatccaaagctgtagagattgaggagcaaaccaaacggcttctagagggcatggagctg atagtcagccaggttcatcctgaaaccaaagaaaatgagatctaccctgtctggtcggga cttccatccctgcagatggctgatgaagagtctcgcctttctgcttattataacctgctc cactgcctacgcagggattcacataaaatcgacaattatctcaagctcctgaagtgccga atcatccacaacaacaactgctaa

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