KEGG   Homo sapiens (human): 5645Help
Entry
5645              CDS       T01001                                 

Gene name
PRSS2, TRY2, TRY8, TRYP2
Definition
(RefSeq) serine protease 2
  KO
K01312  trypsin [EC:3.4.21.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04972  Pancreatic secretion
hsa04974  Protein digestion and absorption
hsa05164  Influenza A
Disease
H00933  Hereditary pancreatitis
Drug target
Ulinastatin: D05183
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5645 (PRSS2)
 09150 Organismal Systems
  09154 Digestive system
   04972 Pancreatic secretion
    5645 (PRSS2)
   04974 Protein digestion and absorption
    5645 (PRSS2)
 09160 Human Diseases
  09167 Infectious diseases
   05164 Influenza A
    5645 (PRSS2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases [BR:hsa01002]
    5645 (PRSS2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5645 (PRSS2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.4  trypsin
     5645 (PRSS2)
Peptidases [BR:hsa01002]
 Serine Peptidases
  Family S1: chymotrypsin family
   5645 (PRSS2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   5645 (PRSS2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Trypsin Trypsin_2 DUF1986
Motif
Other DBs
NCBI-GeneID: 5645
NCBI-ProteinID: NP_002761
OMIM: 601564
HGNC: 9483
Ensembl: ENSG00000275896
Vega: OTTHUMG00000158904
Pharos: P07478(Tchem)
UniProt: P07478 Q5NV56 Q6PK75
LinkDB All DBs
Position
7q34
AA seq 247 aa AA seqDB search
MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVIN
SRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKIT
NNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK
DTIAANS
NT seq 744 nt NT seq  +upstreamnt  +downstreamnt
atgaatctacttctgatccttacctttgttgcagctgctgttgctgccccctttgatgat
gatgacaagatcgttgggggctacatctgtgaggagaattctgtcccctaccaggtgtcc
ttgaattctggctaccacttctgcggtggctccctcatcagcgaacagtgggtggtgtca
gcaggtcactgctacaagtcccgcatccaggtgagactgggagagcacaacatcgaagtc
ctggaggggaatgaacagttcatcaatgcggccaagatcatccgccaccccaaatacaac
agccggactctggacaatgacatcctgctgatcaagctctcctcacctgccgtcatcaat
tcccgcgtgtccgccatctctctgcccactgcccctccagctgctggcaccgagtccctc
atctccggctggggcaacactctgagttctggtgccgactacccagacgagctgcagtgc
ctggatgctcctgtgctgagccaggctgagtgtgaagcctcctaccctggaaagattacc
aacaacatgttctgtgtgggcttcctcgagggaggcaaggattcctgccagggtgattct
ggtggccctgtggtctccaatggagagctccaaggaattgtctcctggggctatggctgt
gcccagaagaacaggcctggagtctacaccaaggtctacaactatgtggactggattaag
gacaccatagctgccaacagctaa

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