Homo sapiens (human): 57134
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Entry
57134 CDS
T01001
Symbol
MAN1C1, HMIC, MAN1A3, MAN1C, pp6318
Name
(RefSeq) mannosidase alpha class 1C member 1
KO
K01230
mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:
3.2.1.113
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00510
N-Glycan biosynthesis
hsa00513
Various types of N-glycan biosynthesis
hsa01100
Metabolic pathways
hsa04141
Protein processing in endoplasmic reticulum
Module
hsa_M00073
N-glycan precursor trimming
Network
nt06015
N-Glycan biosynthesis
Element
N00820
N-Glycan biosynthesis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00510 N-Glycan biosynthesis
57134 (MAN1C1)
00513 Various types of N-glycan biosynthesis
57134 (MAN1C1)
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
57134 (MAN1C1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
57134 (MAN1C1)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.113 mannosyl-oligosaccharide 1,2-alpha-mannosidase
57134 (MAN1C1)
Membrane trafficking [BR:
hsa04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
57134 (MAN1C1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glyco_hydro_47
Motif
Other DBs
NCBI-GeneID:
57134
NCBI-ProteinID:
NP_065112
OMIM:
616772
HGNC:
19080
Ensembl:
ENSG00000117643
UniProt:
Q9NR34
Q59G34
LinkDB
All DBs
Position
1:25616791..25784450
Genome browser
AA seq
630 aa
AA seq
DB search
MLMRKVPGFVPASPWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPRTQQ
PGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREE
ATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKE
MMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAK
AWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTG
IPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI
EKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEA
IETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQ
ITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPI
YREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDL
LSLEDWVFNTEAHPLPVNHSDSSGRAWGRH
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgctcatgaggaaagtgcccggcttcgtcccggcctccccgtgggggctgcggctgccg
cagaagttcctcttcctcctcttcctctcgggcctggtcaccctgtgcttcggggccctc
ttcctgctgccccactcctctcgcctcaagcgcctcttcctggccccccggacccagcag
cctggtctggaagtggtggctgaaatcgccggccatgccccggcccgcgagcaggagccg
cctcccaacccggcccccgccgcgccggccccgggcgaggatgaccccagcagctgggcc
agtccccgccgcaggaaaggggggctgcggcgcacccgccccactggaccccgcgaggag
gccacggcggcccggggcaatagcatcccggcctccaggcccggggacgagggcgtccct
ttccgctttgacttcaacgcattccggagccgtctccgccacccggtcctgggaacgagg
gccgatgagagtcaggagccccagagccaagtgcgagcccagcgggagaaaatcaaggag
atgatgcagtttgcttggcagagctataagcgttatgcaatggggaaaaacgaactccgt
ccactaacaaaagatggctacgagggtaacatgttcggaggcctcagcggggcaacagtc
attgactccctcgataccctctacctcatggagctgaaggaggagttccaggaggccaag
gcctgggtgggagagagcttccacctgaacgtgagcggagaagcatccttgtttgaggtg
aacatccgctacatcgggggactcctctcagccttctacctgacaggagaagaggtgttc
cgaataaaggccatcaggctgggagagaagctcctgccggcgttcaacacccccacggga
atcccaaagggcgtggtgagcttcaaaagtgggaactggggctgggccacagccggcagc
agcagcatcttggcggagtttggatccctgcacttggaattcttacacctcactgaactc
tctggcaaccaggtcttcgctgaaaaggtcaggaacatccgcaaggtcctcaggaagatc
gaaaagccctttggcctctaccccaacttcctcagcccagtgagtgggaactgggtgcaa
caccatgtctcagttggaggactcggggacagtttttatgaatatttgatcaaatcctgg
ttgatgtcgggcaagacagatatggaggctaaaaatatgtactacgaagccttggaggcg
atagagacctacttgctgaatgtctctcccggggggctgacctacattgccgagtggcga
ggggggattctggaccacaagatggggcacctggcctgtttctccgggggcatgatcgcc
cttggcgccgaggatgccaaggaagaaaagagggcccactaccgagagctcgcagcccag
atcaccaagacgtgtcacgagtcatacgcccgctcagacaccaaacttgggcctgaggcc
ttctggtttaactccggcagagaggccgtggccacccagctgagcgagagctactacatc
ctccggccagaggtggtggagagctacatgtacctgtggcgacagacccacaaccccatc
tacagggagtggggctgggaggtggtgctggccttggagaaatactgtcggacagaagcc
ggtttctctgggatccaagacgtgtacagtagcacccccaaccacgacaacaagcagcag
agcttctttctagcggagacactaaagtatctctatcttctgttctctgaagatgacttg
ctctccctggaagactgggtgttcaacaccgaggcccacccactcccggtgaaccactca
gacagctccggcagagcctggggcagacactga
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